#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P96115 uniprotkb:O83554 intact:EBI-1198311|uniprotkb:O83197|intact:EBI-1581520|ensemblbacteria:AAC65150 intact:EBI-1581524|ensemblbacteria:AAC65527 psi-mi:ruvb_trepa(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:TP_0162(locus name) psi-mi:ruva_trepa(display_long)|uniprotkb:TP_0543(locus name)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581528|imex:IM-9152-3018 author score:0.965988396 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|refseq:WP_010881609.1|ensemblbacteria:AAC65150(transcript)|ensemblbacteria:TP_0162(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445 interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65527(transcript)|ensemblbacteria:TP_0543(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881990.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0162; PREY protein TP_0543|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pKRvyji0nd7AkF5U2AAlQB988W0243276 rogid:aHLNgq+EWuZ/1f/E7uW14i1IMBI243276 intact-crc:C7C8717F2B5F3ABC|rigid:A4+YPMpROAE2rEjp88/+9B/aHKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96115 uniprotkb:P16055 intact:EBI-1198311|uniprotkb:O83197|intact:EBI-1581520|ensemblbacteria:AAC65150 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:ruvb_trepa(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:TP_0162(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581534|imex:IM-9152-3019 author score:0.733139527 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|refseq:WP_010881609.1|ensemblbacteria:AAC65150(transcript)|ensemblbacteria:TP_0162(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0162; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pKRvyji0nd7AkF5U2AAlQB988W0243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:E0F25702B7A18AE5|rigid:c/Ydk3RMDsyqXuv4YJPdAZ7njpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83416 uniprotkb:O83070 intact:EBI-1198429|intact:EBI-1581548|ensemblbacteria:AAC65389 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:flih_trepa(display_long)|uniprotkb:fliH(gene name)|psi-mi:fliH(display_short)|uniprotkb:TP_0401(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581552|imex:IM-9152-3020 author score:0.961392351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018035|refseq:WP_010881849.1|ensemblbacteria:AAC65389(transcript)|ensemblbacteria:TP_0401(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0401; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWyoMcP8oPNRsisYyc4bOUwb92k243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:3EBE03ECC688A891|rigid:wBi/XORD0yz5maFRE36W9y0qAWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74932 uniprotkb:O07886 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 intact:EBI-1198695|intact:EBI-1581566|ensemblbacteria:AAC65690 psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:mota_trepa(display_long)|uniprotkb:motA(gene name)|psi-mi:motA(display_short)|uniprotkb:TP_0725(locus name)|uniprotkb:Chemotaxis protein MotA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581562|imex:IM-9152-3021 author score:0.960181386 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR000540(Flagellar motor protein MotA, conserved site)|interpro:IPR002898(MotA/TolQ/ExbB proton channel)|refseq:WP_010882170.1|ensemblbacteria:AAC65690(transcript)|ensemblbacteria:TP_0725(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0716; PREY protein TP_0725|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 rogid:3OvXOYAVlqo9vkKtIsx96P+QdcY243276 intact-crc:F4745CABBCBEF040|rigid:Reii6W2Uyr6n4t0bNwqBgdD9/2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74932 uniprotkb:O83753 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 intact:EBI-1198702|intact:EBI-1581572|ensemblbacteria:AAC65743|ensemblbacteria:AGN75947 psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:o83753_trepa(display_long)|uniprotkb:TP_0774(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581575|imex:IM-9152-3022 author score:0.784001225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR003416(MgtC/SapB transporter)|refseq:WP_010882219.1|ensemblbacteria:AAC65743(transcript)|ensemblbacteria:AGN75947(transcript)|ensemblbacteria:TP_0774(gene)|ensemblbacteria:TPANIC_0774(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0716; PREY protein TP_0774|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 rogid:CRl5LIl/mN17Ny93fonb20RY68c243276 intact-crc:9212E7354E090A4A|rigid:p6Xf+ktU77WOC2gjDS6AKRTqzt0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74932 uniprotkb:O83572 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581584|imex:IM-9152-3023 author score:0.636096308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0716; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:824CE21CE2CE55B7|rigid:jX/XoqFdtOJJiCza2Hw6xu2z0FI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74932 uniprotkb:O83887 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581593|imex:IM-9152-3024 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0716; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:989E9AB4A9745344|rigid:WuykoTOKbCN0Y4W6Fwn6gkEiaBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83414 uniprotkb:O83070 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581599|imex:IM-9152-3126 author score:0.953945377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0399; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:0483D33764F6D5C4|rigid:YRqCPT7kVun5UndNYC8CNUd2sOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O83414 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581609|imex:IM-9152-3127 author score:0.729678219 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0399; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 intact-crc:26B47F06DC272185|rigid:tAOoQ/kIGlRj+2spaiMPRhPjlOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83414 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581618|imex:IM-9152-3128 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0399; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 intact-crc:F17A013CF344A697|rigid:7H2Xsd7lBhdbgEC77MCIAzyVdxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83414 uniprotkb:O83887 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581624|imex:IM-9152-3129 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0399; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:C33557B586AA7725|rigid:BtCm8+bXuneymrYI0vNvD7LwzOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83070 uniprotkb:P74927 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 intact:EBI-1198781|intact:EBI-1581634|ensemblbacteria:AAC65687 psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:flim_trepa(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:TP_0721(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581630|imex:IM-9152-3277 author score:0.953945377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882166.1|interpro:IPR001689(Flagellar motor switch protein FliM)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|ensemblbacteria:AAC65687(transcript)|ensemblbacteria:TP_0721(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0721; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 rogid:fNFvMuPXadT39yPyTgBLAxubE1A243276 intact-crc:BE2199E7FF1DDD4D|rigid:rl4viNpbvA51tp2JcHuHM/bJf1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:P74927 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1198781|intact:EBI-1581634|ensemblbacteria:AAC65687 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:flim_trepa(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:TP_0721(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581643|imex:IM-9152-3278 author score:0.802411005 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 refseq:WP_010882166.1|interpro:IPR001689(Flagellar motor switch protein FliM)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|ensemblbacteria:AAC65687(transcript)|ensemblbacteria:TP_0721(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0721; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:fNFvMuPXadT39yPyTgBLAxubE1A243276 intact-crc:F968F8657FF7D80D|rigid:CthKh7FzPli+SVlaHRpm+Jtfyn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74927 uniprotkb:O83105 intact:EBI-1198781|intact:EBI-1581634|ensemblbacteria:AAC65687 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:flim_trepa(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:TP_0721(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581652|imex:IM-9152-3279 author score:0.740166777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882166.1|interpro:IPR001689(Flagellar motor switch protein FliM)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|ensemblbacteria:AAC65687(transcript)|ensemblbacteria:TP_0721(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0721; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fNFvMuPXadT39yPyTgBLAxubE1A243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:09726F1C3A3439A4|rigid:KA+7oUjxmVkYZJF5Px7w/5avRQ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P74927 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198781|intact:EBI-1581634|ensemblbacteria:AAC65687 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:flim_trepa(display_long)|uniprotkb:fliM(gene name)|psi-mi:fliM(display_short)|uniprotkb:TP_0721(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581661|imex:IM-9152-3130 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010882166.1|interpro:IPR001689(Flagellar motor switch protein FliM)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|ensemblbacteria:AAC65687(transcript)|ensemblbacteria:TP_0721(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0721; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:fNFvMuPXadT39yPyTgBLAxubE1A243276 intact-crc:334AD4F96166A355|rigid:kgQ0w4n7swxebY/63UUOs4IcwqQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21990 uniprotkb:O83664 intact:EBI-1198468|intact:EBI-1581671|ensemblbacteria:AAC65834 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:flab1_trepa(display_long)|uniprotkb:flaB1(gene name)|psi-mi:flaB1(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 34.5 kDa core protein(gene name synonym)|uniprotkb:TP_0868(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581675|imex:IM-9152-3131 author score:0.950325176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882311.1|ensemblbacteria:AAC65834(transcript)|ensemblbacteria:TP_0868(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0868; PREY protein TP_0658|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ldLjWSBOrd9orF0djko0NkaH4QM243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:4E5B2240693FC34B|rigid:XpPjRfOrHI7C9AaIkuAJtJlvAEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:P21990 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1198468|intact:EBI-1581671|ensemblbacteria:AAC65834 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:flab1_trepa(display_long)|uniprotkb:flaB1(gene name)|psi-mi:flaB1(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 34.5 kDa core protein(gene name synonym)|uniprotkb:TP_0868(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581681|imex:IM-9152-3132 author score:0.757020403 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882311.1|ensemblbacteria:AAC65834(transcript)|ensemblbacteria:TP_0868(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0868; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:ldLjWSBOrd9orF0djko0NkaH4QM243276 intact-crc:7D1F8C452C37FF51|rigid:H4BaxvRbL1rN3XtTxRMCxxbko0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:P21990 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198468|intact:EBI-1581671|ensemblbacteria:AAC65834 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:flab1_trepa(display_long)|uniprotkb:flaB1(gene name)|psi-mi:flaB1(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 34.5 kDa core protein(gene name synonym)|uniprotkb:TP_0868(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581693|imex:IM-9152-3133 author score:0.600969391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882311.1|ensemblbacteria:AAC65834(transcript)|ensemblbacteria:TP_0868(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0868; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:ldLjWSBOrd9orF0djko0NkaH4QM243276 intact-crc:89F2FD72CE34B1BC|rigid:1WSZ/IBYyy7kctZat2QWXgkY5qw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83527 uniprotkb:O83364 intact:EBI-1581703|ensemblbacteria:AAC65502 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581699|imex:IM-9152-3134 author score:0.941491474 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 intact-crc:0987949AA3827323|rigid:pk+DniQHYqp6H/xbeBogl4c8V2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83364 uniprotkb:O83518 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 intact:EBI-1581717|ensemblbacteria:AAC65489|ensemblbacteria:AGN75694 psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:o83518_trepa(display_long)|uniprotkb:TP_0505(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581713|imex:IM-9152-3135 author score:0.755487397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR022672|ensemblbacteria:AAC65489(transcript)|ensemblbacteria:AGN75694(transcript)|ensemblbacteria:TP_0505(gene)|ensemblbacteria:TPANIC_0505(gene)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0006096"(glycolytic process)|refseq:WP_010881954.1|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0505|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 rogid:LAsIHHUGP2Wi9tX/xsn5LeL/gyw243276 intact-crc:F057A458DF6554C4|rigid:vRD+SdPiTOul+4H5o2zkE3iAQmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83364 uniprotkb:P45685 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581722|imex:IM-9152-3136 author score:0.66159589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:1FDBBDC7649E9DB5|rigid:VpJp9ZfeLM1Gm+1KrQ1AoLiWO7I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83364 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581741|imex:IM-9152-3138 author score:0.539638423 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 intact-crc:00DBFDB948D96875|rigid:mQHMefLLepyRFNCnKyU1R+Ldn3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83364 uniprotkb:O83805 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581735|imex:IM-9152-3137 author score:0.559628514 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:A0DE2CB436027188|rigid:SORZGgB939r/FntRwlo2Kzm9hpE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83364 uniprotkb:O83574 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581750|imex:IM-9152-3139 author score:0.206071282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:6A4F596CB53D0D33|rigid:PgcYjmvz8TRyyPapb0EpICu2fpg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83364 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1581707|ensemblbacteria:AAC65332|ensemblbacteria:AGN75542 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83364_trepa(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:TP_0344(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581756|imex:IM-9152-3140 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003711(Transcription factor CarD)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|ensemblbacteria:AAC65332(transcript)|ensemblbacteria:AGN75542(transcript)|ensemblbacteria:TP_0344(gene)|ensemblbacteria:TPANIC_0344(gene)|go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881792.1|interpro:IPR027417|interpro:IPR041471|interpro:IPR036101|interpro:IPR037235 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0344; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ThGWFjx0ornntPq8yFylKhK35ak243276 intact-crc:A52E4AAD48B976BF|rigid:czosIOVCqFhF9h9ixascBsu4P0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21991 uniprotkb:O83664 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581766|imex:IM-9152-3141 author score:0.940662443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0658|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:2E9AF87AC629366A|rigid:TZs6tKQMzLNXkwFI38C1SW3DVUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:P21991 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581775|imex:IM-9152-3142 author score:0.73150929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 intact-crc:B8BE4C617BB47F30|rigid:dS7Jqjm/zSjlPNtWfUUPuqEgGPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21991 uniprotkb:O83927 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581781|imex:IM-9152-3143 author score:0.700932099 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:3EE91BC99DDE4115|rigid:cAklb3/pBsfDeO4tPbZVI8Pnpg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21991 uniprotkb:O83195 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581794|imex:IM-9152-3144 author score:0.692926388 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:E063104D7A7AD8D0|rigid:UvfoqX/exa0WZuhUT44VQz3xV1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21991 uniprotkb:O83804 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581800|imex:IM-9152-3145 author score:0.555160027 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:FE625B6BEC539F7C|rigid:AxRl6/sCv22CbGBjqhv6O8THLc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:P21991 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198834|intact:EBI-1581762|ensemblbacteria:AAC65757 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:flab2_trepa(display_long)|uniprotkb:flaB2(gene name)|psi-mi:flaB2(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 33 kDa core protein(gene name synonym)|uniprotkb:TP_0792(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581806|imex:IM-9152-3146 author score:0.172201353 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882237.1|ensemblbacteria:AAC65757(transcript)|ensemblbacteria:TP_0792(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0792; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:1Yx6JC5Png++D+Nz7GGwP/lUF1o243276 intact-crc:740451C300E3AE4F|rigid:fZKlPquGGddD2CTDO5CpCyWeYgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83418 uniprotkb:P21990 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 intact:EBI-1198468|intact:EBI-1581671|ensemblbacteria:AAC65834 psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:flab1_trepa(display_long)|uniprotkb:flaB1(gene name)|psi-mi:flaB1(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 34.5 kDa core protein(gene name synonym)|uniprotkb:TP_0868(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581818|imex:IM-9152-3147 author score:0.932150362 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882311.1|ensemblbacteria:AAC65834(transcript)|ensemblbacteria:TP_0868(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0868|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 rogid:ldLjWSBOrd9orF0djko0NkaH4QM243276 intact-crc:869B92BE90311DF1|rigid:xMbkzIfzzMVAfQwKk9fLKtf0oRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83418 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581828|imex:IM-9152-3148 author score:0.645415983 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 intact-crc:C94ADEFFAF48A5C0|rigid:368CKh6QINZX50Ko4WxLxw3aTU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83418 uniprotkb:O83804 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581834|imex:IM-9152-3149 author score:0.508393644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:4EF7E4EA2833357D|rigid:Ab6WMrP+IwDFh59u1qb8437xziA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83418 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581840|imex:IM-9152-3150 author score:0.465963361 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 intact-crc:7A9C5FD1C522B44A|rigid:A0xqmijhPyAujPVSY91NLlse3QQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83418 uniprotkb:O83969 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581846|imex:IM-9152-3151 author score:0.276367157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:FC93A5508F48B104|rigid:P95knO4RUz8wKL9IrdKXEffRbwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83418 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581859|imex:IM-9152-3152 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 intact-crc:29866FE82F02CBDD|rigid:Gsw5Nc0hUUfTBuFR9+blsZvNWW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83418 uniprotkb:O83574 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581865|imex:IM-9152-3153 author score:0.186323126 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:A4589D912E888808|rigid:sch6LydTdm6HKIbbSaitvIlN0DI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83418 uniprotkb:O83745 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581871|imex:IM-9152-3154 author score:0.062238911 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:8E907AE97954ECA1|rigid:1ovnI/nFnpVkYxQmBvgXlKiMyPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83418 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198232|intact:EBI-1581815|ensemblbacteria:AAC65391|ensemblbacteria:AGN75597 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83418_trepa(display_long)|uniprotkb:TP_0403(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581877|imex:IM-9152-3155 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR012823(Flagellar export FliJ)|refseq:WP_010881851.1|ensemblbacteria:AAC65391(transcript)|ensemblbacteria:AGN75597(transcript)|ensemblbacteria:TP_0403(gene)|ensemblbacteria:TPANIC_0403(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0015031"(protein transport)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0403; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:l++1ACAqX/WzMy/J1tfXK7egrkc243276 intact-crc:EAB54DBBD5726D24|rigid:+Im+v8URM9T/PBdZ3Wo0OxRPcbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83929 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581889|imex:IM-9152-3156 author score:0.93032812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 intact-crc:4B55137F97EDCB51|rigid:tjKHPCT4p57cK5ZPFmxpB8/u50Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83929 uniprotkb:O83398 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581895|imex:IM-9152-3157 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:19F31AF9DE484F62|rigid:1A59dXrcjYshoENWn01GlhekN0Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83929 uniprotkb:O83927 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581905|imex:IM-9152-3158 author score:0.318288202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:6B8D4A7855DF635D|rigid:ipWq3lTt1F9lTBjuaco6yeu8CzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83929 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581915|imex:IM-9152-3159 author score:0.274510541 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 intact-crc:C5B2576255743D1A|rigid:yPDkgjRRoOLnYTVneza8A5Etm7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83929 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581921|imex:IM-9152-3160 author score:0.171913133 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 intact-crc:5A2F851612699B10|rigid:oXvWgotXWFkT1u3RGo7x35Y6Y3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83929 uniprotkb:O83954 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581931|imex:IM-9152-3161 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1CD2EEA4C18E46AE|rigid:FsU+2l5jkWOvGJPSj4vziiRWYHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83929 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1581883|ensemblbacteria:AAC65918|ensemblbacteria:AGN76128 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83929_trepa(display_long)|uniprotkb:TP_0963(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581940|imex:IM-9152-3162 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65918(transcript)|ensemblbacteria:AGN76128(transcript)|ensemblbacteria:TP_0963(gene)|ensemblbacteria:TPANIC_0963(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882407.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0963; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:vKg5J0ZRcByQ7svHqnQcrVUeBow243276 intact-crc:69C09D312343F76A|rigid:K2jQVzGzgcRLAhg1mLvFQQG2c+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83414 uniprotkb:O83415 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581949|imex:IM-9152-3163 author score:0.91986077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0399|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 intact-crc:CCACD597AC14A113|rigid:5ntICGqyV9nBJBmrpTZKVv8vXKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83457 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581955|imex:IM-9152-3164 author score:0.703882489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:E08BC0E6508DE342|rigid:xQCP76H/QhrhNbYpXp3AdsykhWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83654 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581964|imex:IM-9152-3165 author score:0.69805076 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0648|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:7E38453912430D3B|rigid:Y17EruAoMjoCx0bX/9zo7Mma2uY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83261 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581976|imex:IM-9152-3166 author score:0.687787839 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:E5000A7FAD62E615|rigid:H3QNfD0FmmeyUZt3Mi6Wsq9JQxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83130 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581982|imex:IM-9152-3167 author score:0.643046839 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:FF0DBE5E693CD365|rigid:mtoSZ0EhBWlobmr9iVrriFjesio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83129 uniprotkb:O83415 intact:EBI-1198400|intact:EBI-1581992|ensemblbacteria:AAC65085 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 psi-mi:syc_trepa(display_long)|uniprotkb:cysS(gene name)|psi-mi:cysS(display_short)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0091(locus name) psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581988|imex:IM-9152-3168 author score:0.637424712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015273(Cysteinyl-tRNA synthetase, class Ia, DALR)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR024909|interpro:IPR032678|refseq:WP_010881540.1|ensemblbacteria:AAC65085(transcript)|ensemblbacteria:TP_0091(gene)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0091|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Y8gQoNQyNd0xMGf9/d1szovwMFA243276 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 intact-crc:9C1E4B0C64C91C46|rigid:86G97f1sbpEtMQvs/+tm3tw0xSY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83671 uniprotkb:O83415 intact:EBI-1198419|intact:EBI-1582002|ensemblbacteria:AAC65641 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 psi-mi:y665_trepa(display_long)|uniprotkb:TP_0665(locus name) psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1581998|imex:IM-9152-3169 author score:0.637424712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882110.1|ensemblbacteria:AAC65641(transcript)|ensemblbacteria:TP_0665(gene) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0665|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZuRPCYMUky+oJ45TgY0T6UCnjz8243276 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 intact-crc:D2BD668F16DA0F0D|rigid:JJIXQPypZyabIskU7hZUPgI0jgU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83058 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198380|intact:EBI-1582007|ensemblbacteria:AAC65014 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:y014_trepa(display_long)|uniprotkb:TP_0014(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582010|imex:IM-9152-3170 author score:0.631179811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR024258|ensemblbacteria:AAC65014(transcript)|ensemblbacteria:TP_0014(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0014|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:7rMeCmvee8WGRi8XmRFI64EGDm4243276 intact-crc:7801E1680DF3FE92|rigid:SgEdlScpq+5rAXnVVV17tXo7LzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83725 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198423|intact:EBI-1582016|ensemblbacteria:AAC65717 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:rl27_trepa(display_long)|uniprotkb:rpmA(gene name)|psi-mi:rpmA(display_short)|uniprotkb:TP_0743(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582020|imex:IM-9152-3171 author score:0.631179811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001684(Ribosomal protein L27)|interpro:IPR018261|refseq:WP_010882188.1|ensemblbacteria:AAC65717(transcript)|ensemblbacteria:TP_0743(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0743|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:GQ/6oHmhMagaYddfIwAckdCCmUA243276 intact-crc:5819C0235FD3715F|rigid:k6ZDhflDfMYWOi1oyQ2EECfBBQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83070 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582026|imex:IM-9152-3172 author score:0.59284685 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:EA2018F6462E4FA4|rigid:tnyJgYiceXjhdpqG2icfJCs+sHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83415 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582042|imex:IM-9152-3174 author score:0.466106969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 intact-crc:6A22DC4957AF7C1A|rigid:higMwgHNIErLQuGiz1i76a39Z+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83105 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582032|imex:IM-9152-3173 author score:0.573214701 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:75562FBD58BD38F0|rigid:QmmQCNOsnXWcjuzqGxGayeG96p4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83099 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582048|imex:IM-9152-3175 author score:0.181112753 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:CF58A74AC5570ABF|rigid:D2S577NpeuxFPfaZf8dBXUlUPdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83415 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582058|imex:IM-9152-3176 author score:0.128681888 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 intact-crc:24583A4DA4A517E6|rigid:BOxEj6YKqhfXmMTdFooicSEO6oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83745 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582064|imex:IM-9152-3177 author score:0.082124033 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:04B1705A10D74186|rigid:9ZlSg98U1CZPNjhi+eKq6SFseDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83415 uniprotkb:O83958 intact:EBI-1198370|intact:EBI-1581946|ensemblbacteria:AAC65388|ensemblbacteria:AGN75594 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83415_trepa(display_long)|uniprotkb:TP_0400(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582070|imex:IM-9152-3178 author score:0.001707213 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881848.1|ensemblbacteria:AAC65388(transcript)|ensemblbacteria:AGN75594(transcript)|ensemblbacteria:TP_0400(gene)|ensemblbacteria:TPANIC_0400(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0400; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9BzkM57znx4AiBfvUGMvgPxz7XA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1A6B86A1C4401C69|rigid:9RgLdglVJxvRdUobcJQUbDDQrIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:O83417 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1198435|intact:EBI-1582076|ensemblbacteria:AAC65390 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:flii_trepa(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:TP_0402(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582084|imex:IM-9152-3179 author score:0.918053672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR022426|interpro:IPR040627|interpro:IPR027417|refseq:WP_010881850.1|ensemblbacteria:AAC65390(transcript)|ensemblbacteria:TP_0402(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0402; PREY protein TP_0640|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:VXESSRWLEbW5T1/cifXEb1WuQHs243276 intact-crc:B2F11FB53B4B4719|rigid:Kamd/pwBm5lCTLNtuxQj4M23C68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83417 uniprotkb:O83428 intact:EBI-1198435|intact:EBI-1582076|ensemblbacteria:AAC65390 intact:EBI-1198445|intact:EBI-1582090|ensemblbacteria:AAC65401|ensemblbacteria:AGN75608 psi-mi:flii_trepa(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:TP_0402(locus name) psi-mi:o83428_trepa(display_long)|uniprotkb:TP_0413(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582093|imex:IM-9152-3180 author score:0.784001225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR022426|interpro:IPR040627|interpro:IPR027417|refseq:WP_010881850.1|ensemblbacteria:AAC65390(transcript)|ensemblbacteria:TP_0402(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|refseq:WP_010881861.1|ensemblbacteria:AAC65401(transcript)|ensemblbacteria:AGN75608(transcript)|ensemblbacteria:TP_0413(gene)|ensemblbacteria:TPANIC_0413(gene)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016868"(intramolecular transferase activity, phosphotransferases)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0402; PREY protein TP_0413|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXESSRWLEbW5T1/cifXEb1WuQHs243276 rogid:xdf7iMFGW04XcnA65OQGOvw/VAE243276 intact-crc:CC2D03A46E241902|rigid:7hw/5MeQNAQOIkV3YJFnQbII/aw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83417 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1198435|intact:EBI-1582076|ensemblbacteria:AAC65390 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:flii_trepa(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:TP_0402(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582099|imex:IM-9152-3181 author score:0.605304872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR022426|interpro:IPR040627|interpro:IPR027417|refseq:WP_010881850.1|ensemblbacteria:AAC65390(transcript)|ensemblbacteria:TP_0402(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0402; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:VXESSRWLEbW5T1/cifXEb1WuQHs243276 intact-crc:B6C280057D1974C6|rigid:qOYrbu46zTfZJdKJKz5pN+vHqKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83519 uniprotkb:O83614 intact:EBI-1582119|ensemblbacteria:AAC65494 intact:EBI-1582115|ensemblbacteria:AAC65578 psi-mi:tig_trepa(display_long)|uniprotkb:PPIase(gene name synonym)|uniprotkb:TP_0506(locus name)|uniprotkb:tig(gene name)|psi-mi:tig(display_short) psi-mi:efts_trepa(display_long)|uniprotkb:tsf(gene name)|psi-mi:tsf(display_short)|uniprotkb:TP_0605(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582111|imex:IM-9152-3183 author score:0.910021421 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027304|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|ensemblbacteria:AAC65494(transcript)|ensemblbacteria:TP_0506(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0051301"(cell division)|refseq:WP_010881955.1|interpro:IPR036611|interpro:IPR037041 interpro:IPR001816(Translation elongation factor EFTs/EF1B)|interpro:IPR014039(Translation elongation factor EFTs/EF1B, dimerisation)|interpro:IPR018101|interpro:IPR009060(UBA-like)|ensemblbacteria:AAC65578(transcript)|ensemblbacteria:TP_0605(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005737"(cytoplasm)|refseq:WP_010882051.1|interpro:IPR036402 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0506; PREY protein TP_0605|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:woVkgqeQdmN/cNT5tUTecpn4gUs243276 rogid:Fr/T7iu1e/3iQch3j8alPGZ/2Go243276 intact-crc:73AFC31B6DC7D9EA|rigid:E/Rg2zTQha9lmOpx9OglSx7yTtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83417 uniprotkb:O83958 intact:EBI-1198435|intact:EBI-1582076|ensemblbacteria:AAC65390 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:flii_trepa(display_long)|uniprotkb:fliI(gene name)|psi-mi:fliI(display_short)|uniprotkb:TP_0402(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582105|imex:IM-9152-3182 author score:0.002277805 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005714(Type III secretion system ATPase, FliI/YscN)|interpro:IPR022426|interpro:IPR040627|interpro:IPR027417|refseq:WP_010881850.1|ensemblbacteria:AAC65390(transcript)|ensemblbacteria:TP_0402(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009288"(bacterial-type flagellum)|go:"GO:0030254"(protein secretion by the type III secretion system)|go:"GO:0030257"(type III protein secretion system complex)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0402; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXESSRWLEbW5T1/cifXEb1WuQHs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D742FC8F79C6E41B|rigid:3vY5dCK0xZRfOtM5L5K+a/GoCek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83519 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1582119|ensemblbacteria:AAC65494 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:tig_trepa(display_long)|uniprotkb:PPIase(gene name synonym)|uniprotkb:TP_0506(locus name)|uniprotkb:tig(gene name)|psi-mi:tig(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582128|imex:IM-9152-3184 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR027304|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|ensemblbacteria:AAC65494(transcript)|ensemblbacteria:TP_0506(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0051301"(cell division)|refseq:WP_010881955.1|interpro:IPR036611|interpro:IPR037041 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0506; PREY protein TP_0086|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:woVkgqeQdmN/cNT5tUTecpn4gUs243276 intact-crc:41262571ECE9D80E|rigid:Pvj8aXgcDNNd8Vw7aS2kpMTbTjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83845 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1582138|ensemblbacteria:AAC65838 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582134|imex:IM-9152-3185 author score:0.907003657 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 intact-crc:CB71DFB38F67342B|rigid:LaEkV8z6Y2jgOu90sfQ/HTHNndk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83845 uniprotkb:O83268 intact:EBI-1582138|ensemblbacteria:AAC65838 intact:EBI-1582146|ensemblbacteria:AAC65228 psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:rl7_trepa(display_long)|uniprotkb:rplL(gene name)|psi-mi:rplL(display_short)|uniprotkb:TP_0240(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582150|imex:IM-9152-3186 author score:0.848143253 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|ensemblbacteria:AAC65228(transcript)|ensemblbacteria:TP_0240(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881688.1|interpro:IPR036235 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0240|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 rogid:z8V8m1op++Un5wCNg5xzxqKCGQI243276 intact-crc:72BE409C80A577A5|rigid:mZG66epkjWVCr4JlbmUFENMHADE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83845 uniprotkb:P45685 intact:EBI-1582138|ensemblbacteria:AAC65838 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582156|imex:IM-9152-3187 author score:0.675478348 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:828283BADA28D2D0|rigid:fzuhdEiAhteWSlDLJOsN0LyHQIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83845 uniprotkb:O83282 intact:EBI-1582138|ensemblbacteria:AAC65838 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582168|imex:IM-9152-3189 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9C674A73380288AD|rigid:BVY3nqzmNZ9ZWBFKwV/Q0DHWrNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83845 uniprotkb:O83099 intact:EBI-1582138|ensemblbacteria:AAC65838 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582162|imex:IM-9152-3188 author score:0.479950535 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:EB31B3BD950DA00F|rigid:OCP05azGtZvTHn+j8pVqjQQ8DSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83845 uniprotkb:O83958 intact:EBI-1582138|ensemblbacteria:AAC65838 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:tsae_trepa(display_long)|uniprotkb:tsaE(gene name)|psi-mi:tsaE(display_short)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE"(gene name synonym)|uniprotkb:TP_0875(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582177|imex:IM-9152-3190 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003442(Protein of unknown function UPF0079, ATPase bacteria)|ensemblbacteria:AAC65838(transcript)|ensemblbacteria:TP_0875(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882318.1|interpro:IPR027417 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0875; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o+Ikoiupw/gBeYoKn32aHUmPcrs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:524EFD6BCD23A6D7|rigid:TFZU/EPYDqwYHAykEyi1WDiKnqc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:O83913 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582183|imex:IM-9152-3191 author score:0.906090256 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0660|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:33CD12E84FB5E705|rigid:PuluoOPaiglr6bULKbpe4hVQvE0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83913 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582195|imex:IM-9152-3192 author score:0.575143082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:2AE7ECD890A9A1A3|rigid:ZeoiugihZVGzYqFVIM4nHPKQRdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O66107 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582201|imex:IM-9152-3193 author score:0.573117951 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:3065BD554DCC8817|rigid:2b24ph2E2gCQCumuGkGBHnFT5+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83913 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582221|imex:IM-9152-3195 author score:0.531118397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:56D795327E351841|rigid:lW/F6DPSKQI4N0b9Ty60oof1uhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83227 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582215|imex:IM-9152-3194 author score:0.531118397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:E2C64A7FC2DD3DD8|rigid:UpcGkjfZYAVbJLPPaYLxU0bPa9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83927 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582227|imex:IM-9152-3196 author score:0.485391523 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:91D587F9BD9D15E7|rigid:vs42ogRm3zoJeZ6QXAA4E7gcS6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83913 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582233|imex:IM-9152-3197 author score:0.477329271 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:81715E58C3FC5C0F|rigid:UTkAWtzhqFfsTXYSZlcGLz4lYvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83913 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582242|imex:IM-9152-3198 author score:0.450553387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:AB5638D7ADA8FC92|rigid:8W4SVTp18Dtw2tPQNxV/KzLj+Qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83913 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582252|imex:IM-9152-3199 author score:0.323752596 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:255326887786B737|rigid:iYvWBKpRLPHvVCBaGVAHiZoMluU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83398 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582258|imex:IM-9152-3200 author score:0.227674498 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:11CDAAE41C7D9198|rigid:L54vKQR7oqJeh59Kc4RFh1G4ASA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83913 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582264|imex:IM-9152-3201 author score:0.172005321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:CA0A46F64432876B|rigid:GbEaj4494+MV+MpsUAACPs0HGgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83913 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582279|imex:IM-9152-3203 author score:0.067770131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:50FEA9937439F72C|rigid:v5+WAU3XM4d+kgXcV7EssRu7rnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83877 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582270|imex:IM-9152-3202 author score:0.101769179 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:511743CF3F603A84|rigid:Ig9T7tKrOED8CmUEuFp/9eAwVgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83767 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582285|imex:IM-9152-3204 author score:0.046296122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E04F8F53ED9081DD|rigid:8DlxvbQAZOc2yIxPofUbyh+cMQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83913 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582294|imex:IM-9152-3205 author score:0.015842082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:FE15773C8F6EB34B|rigid:EsomyNlLrPNVpeTznLJeNA3Ojpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83913 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582300|imex:IM-9152-3206 author score:0.013156781 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:94D4D8491D3AEC97|rigid:bK0EdAQIjhFm/eE3mE6rRQj7Pcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83958 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582306|imex:IM-9152-3207 author score:0.000788623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0943; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6E387FF0A1F91985|rigid:ItfEErzpT6Hza2ZZhwiL3R02R2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83047 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1582316|ensemblbacteria:AAC64999 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582312|imex:IM-9152-3208 author score:0.901342824 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0001|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 intact-crc:FDAB55D8BFA95B12|rigid:tLjbjk5ofFR1L5XW0Wpy3FkF8MY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83140 uniprotkb:O83097 intact:EBI-1582330|ensemblbacteria:AAC65097|ensemblbacteria:AGN75321 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83140_trepa(display_long)|uniprotkb:TP_0102(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582326|imex:IM-9152-3209 author score:0.884286097 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|ensemblbacteria:AAC65097(transcript)|ensemblbacteria:AGN75321(transcript)|ensemblbacteria:TP_0102(gene)|ensemblbacteria:TPANIC_0102(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881551.1|interpro:IPR027417|interpro:IPR013986(DNA helicase, DEXX box type) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0102|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BIUEEI05QFRVR+0/dfLypthlBR0243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:BD81A05425379DB4|rigid:VW1z9ECqM5XvH4jBb1PLYEVbfxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83097 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582335|imex:IM-9152-3210 author score:0.740828917 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:992EBC038E5B61E8|rigid:VeCEe/WAxKh21feFNrtIpJ7ZhX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83051 uniprotkb:O83097 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582341|imex:IM-9152-3211 author score:0.733123073 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:750C3568E7E865FD|rigid:pcLNMKjOAdZ08HDu5FBOcY7lElo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83866 uniprotkb:O83097 intact:EBI-1582364|ensemblbacteria:AAC65866 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:y896_trepa(display_long)|uniprotkb:TP_0896(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582360|imex:IM-9152-3213 author score:0.592965907 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65866(transcript)|ensemblbacteria:TP_0896(gene) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0896|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:eaoIVijCat8PdDxAr4wmCfeAnnM243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:782318178D20C237|rigid:EeFTcd8JK3jtdvYoDZ81rvNt6NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83097 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582354|imex:IM-9152-3212 author score:0.713058446 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:6B2A82E9CB8A410F|rigid:4RCspZHyl/mfkN07OLrdhQB5u6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83097 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582379|imex:IM-9152-3215 author score:0.54680819 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:980D09345E4FB270|rigid:4n5ufor6yeC4e1/QCM5gp55hsLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83867 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1582373|uniprotkb:Q9L8S8|ensemblbacteria:AAC65852 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83867_trepa(display_long)|uniprotkb:TP_0897(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582369|imex:IM-9152-3214 author score:0.592965907 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65852(transcript)|ensemblbacteria:TP_0897(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0897|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:y95b2chNjqHprky4Hz7Mtv4aFCg243276 intact-crc:98375DE33DD48668|rigid:Ar5dITRDEVp1S7WD1v8qoVT8nEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83105 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582391|imex:IM-9152-3217 author score:0.526728296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:2F6B0BD07E525C5C|rigid:irfF/JqWESgjSdpYVYNS/58gbTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83097 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582385|imex:IM-9152-3216 author score:0.53343445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:2F9CCF992BB65AB4|rigid:dq2QAe1ZspIQ2LaJ0woCRiqx9ns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83097 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582403|imex:IM-9152-3219 author score:0.355953877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:E836931DD002C1D2|rigid:bUTXKLm6+YrY3XDmy3DsQdIAfb8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83097 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582397|imex:IM-9152-3218 author score:0.479650712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:477CE9B3469D9C19|rigid:bwBhreoaOJOvxTAtFPqbovIzv9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83097 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582415|imex:IM-9152-3221 author score:0.158441749 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:193A159596ABE3A0|rigid:Y/RAVnE1UOVR8V5fGz3AcGqp43c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83927 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582409|imex:IM-9152-3220 author score:0.17023058 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:786365D09B75B401|rigid:2IOLmsSjsIxaZ7iwJZLTFbrXbgY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83097 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582433|imex:IM-9152-3224 author score:0.01400239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:874A35E9E581C822|rigid:wMgb63jWSTdORPmDvRgv8P12dBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83574 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582427|imex:IM-9152-3223 author score:0.109035814 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C8AF6F7F23B7FCD3|rigid:ddbKGOt7QwWYR8aqmqKtlndpy3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83877 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582421|imex:IM-9152-3222 author score:0.127637249 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:DFD60A925083737A|rigid:KJy9ml54uMH+Rh4y4He+ORqlpVk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83097 uniprotkb:O83954 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582439|imex:IM-9152-3225 author score:0.011625241 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:2F89D919B560631E|rigid:ZBp4piJpaw+74Y9t+t1dYW/FPIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83097 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582445|imex:IM-9152-3226 author score:0.000916981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0058; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:8EBF72E2F6F5B1DB|rigid:i1XfUVPh018LsvSLzquSSluqjY0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38369 uniprotkb:O07884 intact:EBI-1198806|intact:EBI-1582459|uniprotkb:Q56358|ensemblbacteria:AAC65272 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 psi-mi:tpn50_trepa(display_long)|uniprotkb:tpn50(gene name)|psi-mi:tpn50(display_short)|uniprotkb:Antigen Tpp57(gene name synonym)|uniprotkb:TP_0292(locus name) psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582451|imex:IM-9152-3227 author score:0.891876435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006664(Outer membrane protein, bacterial)|interpro:IPR006690(Outer membrane protein, OmpA-like, conserved site)|interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|refseq:WP_010881741.1|ensemblbacteria:AAC65272(transcript)|ensemblbacteria:TP_0292(gene)|go:"GO:0006811"(ion transport)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|interpro:IPR036737 refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0727; PREY protein TP_0292|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2FH8ZU+fsAWURSKzaV950ycccF0243276 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 intact-crc:A69B09425BDD3115|rigid:fOw10hJuzlEm7zofOOLXMixh3i8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83240 uniprotkb:O83090 intact:EBI-1582475|ensemblbacteria:AAC65199 intact:EBI-1582471|ensemblbacteria:AAC65047 psi-mi:rs13_trepa(display_long)|uniprotkb:rpsM(gene name)|psi-mi:rpsM(display_short)|uniprotkb:TP_0210(locus name) psi-mi:rf1_trepa(display_long)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)|uniprotkb:TP_0051(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582479|imex:IM-9152-3229 author score:0.877534823 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR019980|interpro:IPR018269|ensemblbacteria:AAC65199(transcript)|ensemblbacteria:TP_0210(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881658.1|interpro:IPR027437 interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|ensemblbacteria:AAC65047(transcript)|ensemblbacteria:TP_0051(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0016149"(translation release factor activity, codon specific)|refseq:WP_010881500.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0051; PREY protein TP_0210|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:lpIJO6TLBl77jH2jY17vj/fgxOc243276 rogid:6nEFSVmRO/qZG6FkfbFPLLdSQIg243276 intact-crc:CD8FDC83BCB44E81|rigid:XaHBF5gBxK3uxis+5vbejx4DZ44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07884 uniprotkb:O83239 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582465|imex:IM-9152-3228 author score:0.677298715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0727; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:70054136EAB8A99D|rigid:X1/HD+A3FFxrPIaosOn30H6E6co false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83090 uniprotkb:P16055 intact:EBI-1582471|ensemblbacteria:AAC65047 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:rf1_trepa(display_long)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)|uniprotkb:TP_0051(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582485|imex:IM-9152-3230 author score:0.720703806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|ensemblbacteria:AAC65047(transcript)|ensemblbacteria:TP_0051(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0016149"(translation release factor activity, codon specific)|refseq:WP_010881500.1 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0051; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6nEFSVmRO/qZG6FkfbFPLLdSQIg243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:17E0BE4BA2244DD0|rigid:xx/7N0BBHo7SAh9wsKtpNURAk8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83317 uniprotkb:O83814 intact:EBI-1582508|ensemblbacteria:AAC65273|ensemblbacteria:AGN75499 intact:EBI-1582504|ensemblbacteria:AAC65810 psi-mi:o83317_trepa(display_long)|uniprotkb:TP_0294(locus name) psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582500|imex:IM-9152-3232 author score:0.876269697 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|ensemblbacteria:AAC65273(transcript)|ensemblbacteria:AGN75499(transcript)|ensemblbacteria:TP_0294(gene)|ensemblbacteria:TPANIC_0294(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009165"(nucleotide biosynthetic process)|refseq:WP_010881743.1|interpro:IPR029057|interpro:IPR029099 interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0842; PREY protein TP_0294|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:F8ONQ46scJ3Eu+h6lG8Ga5wZo/4243276 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 intact-crc:D25E46D287A7225A|rigid:L8hWkoryMYym00UXovsh0YmGzOM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83090 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1582471|ensemblbacteria:AAC65047 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:rf1_trepa(display_long)|uniprotkb:prfA(gene name)|psi-mi:prfA(display_short)|uniprotkb:TP_0051(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582494|imex:IM-9152-3231 author score:0.709737695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004373(Peptide chain release factor 1)|ensemblbacteria:AAC65047(transcript)|ensemblbacteria:TP_0051(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0016149"(translation release factor activity, codon specific)|refseq:WP_010881500.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0051; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:6nEFSVmRO/qZG6FkfbFPLLdSQIg243276 intact-crc:B9902534D93F0975|rigid:wzagOwh/K1IbQU5nLZGwdohiIMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83814 uniprotkb:O83282 intact:EBI-1582504|ensemblbacteria:AAC65810 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582523|imex:IM-9152-3234 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0842; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:E8BE38A38B772876|rigid:MGDAWW9v2zHcceFJFOEaknxaTOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83814 uniprotkb:O83373 intact:EBI-1582504|ensemblbacteria:AAC65810 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582517|imex:IM-9152-3233 author score:0.809637503 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0842; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:4B0124BF1FB5159E|rigid:nl8Jcvj7d18H/UJC8sUYMoQh6WM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83861 uniprotkb:O83350 intact:EBI-1582542|ensemblbacteria:AAC26581 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 psi-mi:if2_trepa(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:TP_0891(locus name) psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582535|imex:IM-9152-3236 author score:0.875173105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR044145|ensemblbacteria:AAC26581(transcript)|ensemblbacteria:TP_0891(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR036925 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0891|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WX9JOC/Dy+FEJolWvf7M4MEWMwI243276 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 intact-crc:C51990EDBFB97FE9|rigid:ka5ZmCyIG7aa4e/tDeA5Ia8U4hk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83814 uniprotkb:O83958 intact:EBI-1582504|ensemblbacteria:AAC65810 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582529|imex:IM-9152-3235 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0842; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:A981A5FB411951B8|rigid:KtBLAHqctstGa5QFGHE7zIKlfhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83350 uniprotkb:O83402 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582551|imex:IM-9152-3237 author score:0.801695565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0387|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:2CC3A6CDCBE9E106|rigid:0RSNOWkm43hggtnBAPxZxBFYcB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83350 uniprotkb:O83164 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 intact:EBI-1582567|ensemblbacteria:AAC65119 psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:y127_trepa(display_long)|uniprotkb:TP_0127(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582570|imex:IM-9152-3239 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) interpro:IPR024471|ensemblbacteria:AAC65119(transcript)|ensemblbacteria:TP_0127(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0127|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 rogid:3kc0i0bsYM+aljfxtBk1MWLd8CA243276 intact-crc:31913C62FC72BBC9|rigid:IBDFFtMTW+srW9rNM+L5aeRcMgQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83350 uniprotkb:O83647 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582561|imex:IM-9152-3238 author score:0.763165847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:5D26AEB209A6C5B7|rigid:FvGIbtNvqDb5TDN+Kp4odeCxCtY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83512 uniprotkb:O83350 intact:EBI-1582576|ensemblbacteria:AAC65486|ensemblbacteria:AGN75689 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 psi-mi:o83512_trepa(display_long)|uniprotkb:TP_0499(locus name) psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582579|imex:IM-9152-3240 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017225(Cell shape-determining protein MreD, predicted)|interpro:IPR007227(Cell shape-determining protein MreD)|ensemblbacteria:AAC65486(transcript)|ensemblbacteria:AGN75689(transcript)|ensemblbacteria:TP_0499(gene)|ensemblbacteria:TPANIC_0499(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881948.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0499|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gsifFJ+3XwpDmrTw4ngHj7sGTDI243276 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 intact-crc:CC0BAF5B65E78F5E|rigid:skDYTIEjFlkhmAOdPGVRWUNZsGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83350 uniprotkb:P21992 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582591|imex:IM-9152-3242 author score:0.469068758 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:E48DFF794B228835|rigid:rddIouez2i0wTZ9XhlOgMMrpgaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83350 uniprotkb:O83350 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582585|imex:IM-9152-3241 author score:0.738564161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0330|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 intact-crc:5BC96DC59DC4D15F|rigid:Lf3sbgJQlGrTVGwlxr3kML225Xo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83527 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1581703|ensemblbacteria:AAC65502 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582603|imex:IM-9152-3244 author score:0.873635248 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0965; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 intact-crc:2378446BD790A564|rigid:+p+gtvmUrF6DK+/jSwFAitDyGj8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83350 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582597|imex:IM-9152-3243 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0330; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 intact-crc:F56C715488DCA3EF|rigid:Fbkctu8eNoDEJv1dRNMiYFcJjTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83958 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582615|imex:IM-9152-3246 author score:0.004079814 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0965; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1D2371AF09365036|rigid:rUSCnHRTiEU5uWrgVuAgzXDjsBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83574 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582609|imex:IM-9152-3245 author score:0.250086168 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0965; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:2B035E5851CD71E3|rigid:ke9qFFEWa0+HKM1vyVrxxHH9bDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83056 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582634|imex:IM-9152-3248 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0012|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:D8D92A18A99DCF40|rigid:cNfLyOcImYhq79tDhp74gtgtTC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83513 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582621|imex:IM-9152-3247 author score:0.87159185 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0252|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 intact-crc:6A0C1FEF50CB9709|rigid:dsEcCANd81Hyx4oSWHBg16CwV78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83513 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582653|imex:IM-9152-3250 author score:0.436439494 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 intact-crc:B8B0F944229DECC6|rigid:ffDQTvx7/UjlFs0Kad5vivJwXB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83970 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582643|imex:IM-9152-3249 author score:0.655462037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:CB308D09185A50DB|rigid:CA5jOX4PXvOoVqQ6yVRayVlkzAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83877 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582665|imex:IM-9152-3252 author score:0.238937521 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:59E0923012574B17|rigid:M1IRt59kTZppBnZajpy7wbO/gIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83927 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582659|imex:IM-9152-3251 author score:0.307684079 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:4E7B5B58840EC595|rigid:j/3dKHzpLgZwh6FzKsK+OXevV58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83954 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582671|imex:IM-9152-3253 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F58DC8DB5B92D2F3|rigid:fV/qCZ/2A9mXP1FbjQEI2jOWQik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83725 uniprotkb:O83987 intact:EBI-1198423|intact:EBI-1582016|ensemblbacteria:AAC65717 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:rl27_trepa(display_long)|uniprotkb:rpmA(gene name)|psi-mi:rpmA(display_short)|uniprotkb:TP_0743(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582687|imex:IM-9152-3255 author score:0.871398048 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001684(Ribosomal protein L27)|interpro:IPR018261|refseq:WP_010882188.1|ensemblbacteria:AAC65717(transcript)|ensemblbacteria:TP_0743(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0743|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GQ/6oHmhMagaYddfIwAckdCCmUA243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:62D420721B87344F|rigid:aW/bEaCFW6fw6EiplyI+RggR2RM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83513 uniprotkb:O83958 intact:EBI-1582629|ensemblbacteria:AAC65487|ensemblbacteria:AGN75690 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83513_trepa(display_long)|uniprotkb:TP_0500(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582677|imex:IM-9152-3254 author score:0.006929366 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR017790(Penicillin-binding protein 2)|ensemblbacteria:AAC65487(transcript)|ensemblbacteria:AGN75690(transcript)|ensemblbacteria:TP_0500(gene)|ensemblbacteria:TPANIC_0500(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016020"(membrane)|refseq:WP_010881949.1|interpro:IPR036138 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0500; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:psdm23uq2PUyCM623FAgZSSEZfA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9CED0FAECC05B361|rigid:wdxsdCt8J6k5Y0h+K858JP7gGEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83987 uniprotkb:O83098 intact:EBI-1582683|ensemblbacteria:AAC65981 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582705|imex:IM-9152-3257 author score:0.599091869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:1662B39EF11E5371|rigid:HnaSOVDw4LzTbU0O81GFq0oANtM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83987 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582693|imex:IM-9152-3256 author score:0.649550157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:F7B8561FD1B157B3|rigid:uzT2HPlPEIuBYXZRaGjwUwWmk0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83987 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582711|imex:IM-9152-3258 author score:0.264014076 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:F89D2B893B54BD1A|rigid:+/8ZJEovawo6FxyMo90rUhEm0yc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83987 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582723|imex:IM-9152-3260 author score:0.108892141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:56FD68B1239BDCFB|rigid:cAiQcJZMHANyOdxzxax/RQyUdgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83987 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582717|imex:IM-9152-3259 author score:0.243626594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:7E166074377F7D9B|rigid:Q9lHQDXG84GeW1474L74G8QcN9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83987 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1582683|ensemblbacteria:AAC65981 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582729|imex:IM-9152-3261 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 intact-crc:7D59C4D722E58937|rigid:1VwbKYzTs9XHMDZiuWXuF+0OyrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83987 uniprotkb:O83954 intact:EBI-1582683|ensemblbacteria:AAC65981 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582741|imex:IM-9152-3263 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:15D0824C1E4CF67D|rigid:7XvRAwxxxmdcAdRQLyRZucvZVsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83987 uniprotkb:O83282 intact:EBI-1582683|ensemblbacteria:AAC65981 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582735|imex:IM-9152-3262 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:6696BEE537065C82|rigid:JgCTXmqdQP9Atku4TUUEMri74Aw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83987 uniprotkb:O83958 intact:EBI-1582683|ensemblbacteria:AAC65981 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rs9_trepa(display_long)|uniprotkb:rpsI(gene name)|psi-mi:rpsI(display_short)|uniprotkb:TP_1024(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582747|imex:IM-9152-3264 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR023035|interpro:IPR020574|ensemblbacteria:AAC65981(transcript)|ensemblbacteria:TP_1024(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882468.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1024; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e2datCmR6eCUAXovL02dWKP7w3E243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:09474B0BF8C53756|rigid:dBezghiQlHBdZGItLC8kdvEJV1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83643 uniprotkb:O83667 intact:EBI-1582760|ensemblbacteria:AAC65610|ensemblbacteria:AGN75816 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83643_trepa(display_long)|uniprotkb:TP_0636(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582765|imex:IM-9152-3266 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65610(transcript)|ensemblbacteria:AGN75816(transcript)|ensemblbacteria:TP_0636(gene)|ensemblbacteria:TPANIC_0636(gene)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|refseq:WP_010882081.1|interpro:IPR003717(Recombination protein O, RecO)|interpro:IPR037278 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0636; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QpYP986ifvnFDLDe9ulYEElGHfY243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:7DD79696A405C712|rigid:cEssq0X/Df3VKEjB1RQsoSJUuAs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83643 uniprotkb:O83752 intact:EBI-1582760|ensemblbacteria:AAC65610|ensemblbacteria:AGN75816 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83643_trepa(display_long)|uniprotkb:TP_0636(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582756|imex:IM-9152-3265 author score:0.870008981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65610(transcript)|ensemblbacteria:AGN75816(transcript)|ensemblbacteria:TP_0636(gene)|ensemblbacteria:TPANIC_0636(gene)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|refseq:WP_010882081.1|interpro:IPR003717(Recombination protein O, RecO)|interpro:IPR037278 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0636; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QpYP986ifvnFDLDe9ulYEElGHfY243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:AAF96DCB1E9FBD5A|rigid:rFucmZcBfoRLaIkb8+W+FDff7uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83482 uniprotkb:O83077 intact:EBI-1582780|ensemblbacteria:AAC65450 intact:EBI-1582777|ensemblbacteria:AAC65029 psi-mi:o83482_trepa(display_long)|uniprotkb:TP_0469(locus name) psi-mi:y034_trepa(display_long)|uniprotkb:TP_0034(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582783|imex:IM-9152-3268 author score:0.869107075 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65450(transcript)|ensemblbacteria:TP_0469(gene) ensemblbacteria:AAC65029(transcript)|ensemblbacteria:TP_0034(gene)|go:"GO:0007155"(cell adhesion)|go:"GO:0030001"(metal ion transport)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|interpro:IPR006128(Adhesion lipoprotein) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0034; PREY protein TP_0469|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nAw1P0S86smynE/4ogE1RDNgE24243276 rogid:KWhPDsTIcnWUpEkgiin3aHXNfo0243276 intact-crc:F157D7094EE6ECD2|rigid:bHck6MAN6+p4Num68Nain20Ik5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83643 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582760|ensemblbacteria:AAC65610|ensemblbacteria:AGN75816 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83643_trepa(display_long)|uniprotkb:TP_0636(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582771|imex:IM-9152-3267 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65610(transcript)|ensemblbacteria:AGN75816(transcript)|ensemblbacteria:TP_0636(gene)|ensemblbacteria:TPANIC_0636(gene)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|refseq:WP_010882081.1|interpro:IPR003717(Recombination protein O, RecO)|interpro:IPR037278 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0636; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:QpYP986ifvnFDLDe9ulYEElGHfY243276 intact-crc:7B816FDCF3FFA499|rigid:0+RrZoa2DSDoRiamQnuj63XoGhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83077 uniprotkb:O83767 intact:EBI-1582777|ensemblbacteria:AAC65029 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y034_trepa(display_long)|uniprotkb:TP_0034(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582798|imex:IM-9152-3270 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65029(transcript)|ensemblbacteria:TP_0034(gene)|go:"GO:0007155"(cell adhesion)|go:"GO:0030001"(metal ion transport)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|interpro:IPR006128(Adhesion lipoprotein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0034; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KWhPDsTIcnWUpEkgiin3aHXNfo0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:1CF55AA1B0CB378D|rigid:geTiAilnhGT5pmrjnNTTqeEfl/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83077 uniprotkb:O83777 intact:EBI-1582777|ensemblbacteria:AAC65029 intact:EBI-1582789|ensemblbacteria:AAC65768 psi-mi:y034_trepa(display_long)|uniprotkb:TP_0034(locus name) psi-mi:y799_trepa(display_long)|uniprotkb:TP_0799(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582792|imex:IM-9152-3269 author score:0.794422532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65029(transcript)|ensemblbacteria:TP_0034(gene)|go:"GO:0007155"(cell adhesion)|go:"GO:0030001"(metal ion transport)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|interpro:IPR006128(Adhesion lipoprotein) ensemblbacteria:AAC65768(transcript)|ensemblbacteria:TP_0799(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0034; PREY protein TP_0799|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KWhPDsTIcnWUpEkgiin3aHXNfo0243276 rogid:jY5xnPna4k8h37+WC4al4IEHqTQ243276 intact-crc:162373C709519795|rigid:w5/WUDFDReS9KFE2BRhjZfjvZdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66076 uniprotkb:O83706 intact:EBI-1582812|ensemblbacteria:AAC65245 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:pgsa_trepa(display_long)|uniprotkb:pgsA(gene name)|psi-mi:pgsA(display_short)|uniprotkb:pgs(gene name synonym)|uniprotkb:Phosphatidylglycerophosphate synthase(gene name synonym)|uniprotkb:TP_0256(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582818|imex:IM-9152-3272 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65245(transcript)|ensemblbacteria:TP_0256(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0008444"(CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR004570(CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase)|refseq:WP_010881705.1|interpro:IPR043130 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0256; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AiOd7L6RN1DBMAAmQeslbqrTQR8243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:58E010031F1C68AB|rigid:nzAmB04BWo2xlSJL69ZYICqIql0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66076 uniprotkb:O83746 intact:EBI-1582812|ensemblbacteria:AAC65245 intact:EBI-1582804|ensemblbacteria:AAC65728 psi-mi:pgsa_trepa(display_long)|uniprotkb:pgsA(gene name)|psi-mi:pgsA(display_short)|uniprotkb:pgs(gene name synonym)|uniprotkb:Phosphatidylglycerophosphate synthase(gene name synonym)|uniprotkb:TP_0256(locus name) psi-mi:ftsh_trepa(display_long)|uniprotkb:ftsH(gene name)|psi-mi:ftsH(display_short)|uniprotkb:TP_0765(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582808|imex:IM-9152-3271 author score:0.865349273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65245(transcript)|ensemblbacteria:TP_0256(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0008444"(CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR004570(CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase)|refseq:WP_010881705.1|interpro:IPR043130 ensemblbacteria:AAC65728(transcript)|ensemblbacteria:TP_0765(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0005524"(ATP binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR000642(Peptidase M41)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0256; PREY protein TP_0765|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AiOd7L6RN1DBMAAmQeslbqrTQR8243276 rogid:zWGHvScW/wuy/c/u+Jp7mBjrhHQ243276 intact-crc:1EDACC97E8C58836|rigid:FOwSvbh/KkSfLyOZM2tiHaofnU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83812 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582833|imex:IM-9152-3274 author score:0.865320405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:B686F20414742F4E|rigid:FEX2JygTUBYPwc7M00xlvgG277s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66076 uniprotkb:O83887 intact:EBI-1582812|ensemblbacteria:AAC65245 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:pgsa_trepa(display_long)|uniprotkb:pgsA(gene name)|psi-mi:pgsA(display_short)|uniprotkb:pgs(gene name synonym)|uniprotkb:Phosphatidylglycerophosphate synthase(gene name synonym)|uniprotkb:TP_0256(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582824|imex:IM-9152-3273 author score:0.600702906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65245(transcript)|ensemblbacteria:TP_0256(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0008444"(CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR004570(CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase)|refseq:WP_010881705.1|interpro:IPR043130 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0256; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AiOd7L6RN1DBMAAmQeslbqrTQR8243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:18EC7D8002B4EED3|rigid:lqKtfCrTl97ChAr74kJy8TiCVpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83812 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582839|imex:IM-9152-3275 author score:0.559993165 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:F868CA20A43DFCDE|rigid:DyGSUP9S+7gjAZSP/+d7SYrdxL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83412 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582845|imex:IM-9152-3276 author score:0.479527603 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:DB6DB62A858723E7|rigid:ygMfyNTaAJ4w0rZ4PVRUkd3kpQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83812 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582854|imex:IM-9152-3280 author score:0.462674887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:1AA3EC213EC5AF79|rigid:93a+rbDIQfGF8zZrQCG1zp+PFy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83812 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582866|imex:IM-9152-3282 author score:0.322233386 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:B0621AEA6E91AC20|rigid:PeHyqicBwH2ZjGNNB8Inhobx4O4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83812 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582860|imex:IM-9152-3281 author score:0.348617728 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:B776E17A760CCF89|rigid:T0+gfVGu3egTjeh19/s5hQ0iUvU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83463 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582875|imex:IM-9152-3283 author score:0.313906279 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:ACC39986AC535AAC|rigid:Wq4cL280X2D9hKIsq8bidIY95DQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83812 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582881|imex:IM-9152-3284 author score:0.253301082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:DFAE31FE332A31D4|rigid:dVb717JSeA8KMTO3zpR0rnetvXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83305 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582890|imex:IM-9152-3285 author score:0.243808428 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:D560D96A5EB30606|rigid:dA9rfiEoRNQ7pJtpmmsfQ7cpobM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83574 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582896|imex:IM-9152-3286 author score:0.128681888 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:A2E090F924CFF23C|rigid:SZTSQn/UEpKegDTebRcnpcWuVqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83812 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582908|imex:IM-9152-3288 author score:0.077412371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 intact-crc:4D2FC21686C8B8E4|rigid:2258fMspshw66W6qozROb2A5Q0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83877 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582902|imex:IM-9152-3287 author score:0.085462104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C957709550E0AFB5|rigid:14B65w4c7Mv/Sd03/hNkB8ynsMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83282 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582920|imex:IM-9152-3290 author score:0.016849158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:1332DE686CF1A524|rigid:DEii/JKNdJ7oKw8uz5zCcluMSV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83767 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582914|imex:IM-9152-3289 author score:0.049142483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:C3364BE09C22C84A|rigid:id6b34CPHeh0W1iOlRTTWo4ZsGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83954 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582926|imex:IM-9152-3291 author score:0.013995581 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:2522B6896B67EC1B|rigid:NscKMTys1im73KVvTx9jl+2gd6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O07884 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582938|imex:IM-9152-3293 author score:0.865116398 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0727|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 intact-crc:0781FA99D1302CC9|rigid:2HE3LHIRqI+4s9vIAzu9xCVmrKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83812 uniprotkb:O83958 intact:EBI-1582830|ensemblbacteria:AAC65806|ensemblbacteria:AGN76010 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83812_trepa(display_long)|uniprotkb:TP_0840(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582932|imex:IM-9152-3292 author score:0.001377016 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblbacteria:AAC65806(transcript)|ensemblbacteria:AGN76010(transcript)|ensemblbacteria:TP_0840(gene)|ensemblbacteria:TPANIC_0840(gene)|refseq:WP_010882284.1|interpro:IPR036259 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0840; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:slL0Pvq687N/HofReSLC3XFfXxM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:CA516BBC48632D96|rigid:Gu1Jprw9mLWheFoj+5aIZR//iX8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07885 uniprotkb:O07893 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582961|imex:IM-9152-3295 author score:0.754468476 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:618683362DE31097|rigid:IbanyXJWZWMVS9aeUsaa0C+4364 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O07893 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582951|imex:IM-9152-3294 author score:0.830507335 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:C26B195F973F1282|rigid:8VXGg0yu5Kd4RRtQzbp13+qmXjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83138 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582967|imex:IM-9152-3296 author score:0.58155864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0100|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 intact-crc:B1C7EFED11691789|rigid:S6wB0DvBtITARbA2ntgcJhYvQLU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83588 uniprotkb:O07893 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582982|imex:IM-9152-3298 author score:0.488821012 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0579|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:472A243C9AA64FB4|rigid:C8A64gE+y0iK+3vJTsOSHvL/zJM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83195 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582976|imex:IM-9152-3297 author score:0.501526329 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:78CB878AF934D482|rigid:c+mXUy6lV/rm00R7IdMYs8N7kJs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83051 uniprotkb:O07893 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583006|imex:IM-9152-3301 author score:0.461970263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:86E539E074F62CB7|rigid:am1MQxsA2dbdkjnVGkiRPnCLnRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:P21992 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583000|imex:IM-9152-3300 author score:0.464700901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:4E4BAE3081075D54|rigid:O+CrGJ74uMjnOElSTZN6D7RBnt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83637 uniprotkb:O07893 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1582994|imex:IM-9152-3299 author score:0.482096188 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:86B819ED10B5DD25|rigid:vAMc6u4I00w7qjZoe04zz1lwVw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83927 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583018|imex:IM-9152-3303 author score:0.432826372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:33B9203F6264F763|rigid:2B5WxrWx9rbf39nPM1qivVuKKOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O07893 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583012|imex:IM-9152-3302 author score:0.455285829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:ADC4C0506465C18D|rigid:zbsnRqoV1tXjzGdgzeqb7JLBzos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83565 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583036|imex:IM-9152-3306 author score:0.310335189 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:D807ACAA5B8806F1|rigid:/jraetCW/tY7ol+W2nUNZhNq+i4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:P45685 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583030|imex:IM-9152-3305 author score:0.402582635 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:774A472C187D6523|rigid:RAaahUzgJHP2VWv4cTb2n9lzpV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83595 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583024|imex:IM-9152-3304 author score:0.415598004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:35647B4C727048B8|rigid:Fy5s/dMtFRqv5luuNEZDmND4bh0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O07893 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583051|imex:IM-9152-3308 author score:0.250649962 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:CAA7967427A04CF5|rigid:xj8DBLY7etC4vxEbI+gVKXQJaHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83804 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583045|imex:IM-9152-3307 author score:0.287769325 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:840EB4FFAF476AF5|rigid:v8SdA7sSUXKngcUroPoejutVyTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O07893 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583063|imex:IM-9152-3310 author score:0.06894771 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:509AF45EF65D2DE1|rigid:Lkfu0vjkC9/Iw5Lr8LtUBtY5o58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83574 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583057|imex:IM-9152-3309 author score:0.082118777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:907C340890C792E1|rigid:v1IGsoziXUZFwzVL+m5zQmAoF8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83667 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583075|imex:IM-9152-3312 author score:0.044785961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:BACE54EDDFF26C00|rigid:Syn43nfoIk+PO6pwwvZDJOBKbMA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O07893 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583069|imex:IM-9152-3311 author score:0.059695483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:D641C992F4E0175D|rigid:Jy6P4ftmDuTvsxEXsy9ottCls20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O07893 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583087|imex:IM-9152-3314 author score:0.010275142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:FDF573992BEA95AD|rigid:7IwRYrD9Mnk35s/axywn8dsaoNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83767 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583081|imex:IM-9152-3313 author score:0.030357676 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:F666305E4EEA2ECF|rigid:TSzeWF1EW5oJu0/Vb89ghabUv1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O07893 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583099|imex:IM-9152-3316 author score:0.000662908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 intact-crc:8F7592FC48E69D05|rigid:Zk/cqRY8Hg3+6n1NB68nYOeo1B4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83954 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583093|imex:IM-9152-3315 author score:0.008525287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0728; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:CE7E5774F5AB5751|rigid:6KRhvW0RL630nPZIdf1TG252a1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83712 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1583119|ensemblbacteria:AAC65698|ensemblbacteria:AGN75904 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83712_trepa(display_long)|uniprotkb:TP_0730(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583122|imex:IM-9152-3318 author score:0.860969259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|ensemblbacteria:AAC65698(transcript)|ensemblbacteria:AGN75904(transcript)|ensemblbacteria:TP_0730(gene)|ensemblbacteria:TPANIC_0730(gene)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016780"(phosphotransferase activity, for other substituted phosphate groups)|refseq:WP_010882175.1|interpro:IPR043130 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0730; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:QIxXTddxqwNSC6ws8Jk8KE2zPJw243276 intact-crc:69EBC3CF0D3C2790|rigid:oh/KByQ3a5nhNDwYpcgJASPAs40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83222 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1583109|ensemblbacteria:AAC65177 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:rl2_trepa(display_long)|uniprotkb:rplB(gene name)|psi-mi:rplB(display_short)|uniprotkb:TP_0192(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583113|imex:IM-9152-3317 author score:0.861054723 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022666|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR005880(Ribosomal protein L2, bacterial-type)|interpro:IPR022669|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|ensemblbacteria:AAC65177(transcript)|ensemblbacteria:TP_0192(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016740"(transferase activity)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881639.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0192; PREY protein TP_0756|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:VUjnMNW+BLMsT1Qxilv1N/DaIV8243276 intact-crc:023C2841F5D60E7A|rigid:8XX+H5lEkgdQ4TGuoD7fUfjIfAc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83484 uniprotkb:O83436 intact:EBI-1583128|ensemblbacteria:AAC65460|ensemblbacteria:AGN75663 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:o83484_trepa(display_long)|uniprotkb:TP_0471(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583131|imex:IM-9152-3319 author score:0.860787327 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881920.1|ensemblbacteria:AAC65460(transcript)|ensemblbacteria:AGN75663(transcript)|ensemblbacteria:TP_0471(gene)|ensemblbacteria:TPANIC_0471(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0471; PREY protein TP_0421|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G9TAE5qEwO7P/X2TsrCx62myjY4243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:2E78E20DAB0845D7|rigid:RuXhQqFqHSsnLQZthOM8i1HvmIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83484 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1583128|ensemblbacteria:AAC65460|ensemblbacteria:AGN75663 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83484_trepa(display_long)|uniprotkb:TP_0471(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583146|imex:IM-9152-3321 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 refseq:WP_010881920.1|ensemblbacteria:AAC65460(transcript)|ensemblbacteria:AGN75663(transcript)|ensemblbacteria:TP_0471(gene)|ensemblbacteria:TPANIC_0471(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0471; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:G9TAE5qEwO7P/X2TsrCx62myjY4243276 intact-crc:ABD7F6DB6CC4A991|rigid:gk7ic/Tw6dmzb6EprQp4VTNhR/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83484 uniprotkb:O83413 intact:EBI-1583128|ensemblbacteria:AAC65460|ensemblbacteria:AGN75663 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83484_trepa(display_long)|uniprotkb:TP_0471(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583140|imex:IM-9152-3320 author score:0.24273874 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881920.1|ensemblbacteria:AAC65460(transcript)|ensemblbacteria:AGN75663(transcript)|ensemblbacteria:TP_0471(gene)|ensemblbacteria:TPANIC_0471(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0471; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G9TAE5qEwO7P/X2TsrCx62myjY4243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:5E23842B55401BA4|rigid:f6a4NwasOEkdA9vJUqlCSEwW1P0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O52778 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583152|imex:IM-9152-3322 author score:0.856992742 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 intact-crc:995296339C70D6B9|rigid:NXQ81RCI4mcguh+lT8Y08UUEoeo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:O83103 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583158|imex:IM-9152-3323 author score:0.73150929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 intact-crc:A641F7FE5FCDC35A|rigid:Gpw8EO3E9xzrUlLbY046RhzDwyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O52778 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583173|imex:IM-9152-3325 author score:0.555160027 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 intact-crc:08520D7368C4E1A8|rigid:S5LwlA3lccc/Rn8O6DZjy1W6kuw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:O83126 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583167|imex:IM-9152-3324 author score:0.73150929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:E95B8C641B77653F|rigid:Y5h3z7Nh8BI7RzHRJ7mincTZ8p8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O52778 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583185|imex:IM-9152-3327 author score:0.320205837 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 intact-crc:2B9C2E28930F41CD|rigid:uCKhbUHy4bWEZUbRWc68I6AY5mA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:O83312 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583179|imex:IM-9152-3326 author score:0.42020431 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0640; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:5AFA9D6514E5AE35|rigid:JPKPXvZLRokLD344z6fwe3DAhFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83195 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583201|imex:IM-9152-3329 author score:0.651552908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:C95553C93CB314CE|rigid:6i/XPMZ7vf8F5U3wySX6GmqBwQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83527 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1581703|ensemblbacteria:AAC65502 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583191|imex:IM-9152-3328 author score:0.856925073 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 intact-crc:758F4D85FFFBCA5E|rigid:TkI/c6iiNJw3w+RUgIzUCsspFYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83927 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583207|imex:IM-9152-3330 author score:0.406536344 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:77DD0B9AE5B91B1B|rigid:vbfnwNk13jP9nIoaUEVkuHB4GUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83667 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583225|imex:IM-9152-3333 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C180283B29F4B55C|rigid:hz7x7Xf0vBo2u+QnEAmrAWd0LYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83312 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583219|imex:IM-9152-3332 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:5EC6801D90663594|rigid:tEdi+cNU9sZEiFLJ84Ap6YhuYjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O66106 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583213|imex:IM-9152-3331 author score:0.302743978 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:13B5486BC647B9FF|rigid:gthBiS+gM3yepED1Fh11upmzioM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83282 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583231|imex:IM-9152-3334 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9F488C0108F63BE9|rigid:M8ZOR/i6iF9JSPLJ6V895rOc/N0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83958 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583243|imex:IM-9152-3336 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:96B76A70DF096A35|rigid:w1zXs12Kql7Ts6UGWMAlmNzqleo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83954 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583237|imex:IM-9152-3335 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0946; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:DF9BA30034D56396|rigid:/yUVoPE0dGz0WVUcS7ej2nFZI8s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:P19478 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1583249|ensemblbacteria:AAC65921 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:ta34_trepa(display_long)|uniprotkb:tpd(gene name)|psi-mi:tpd(display_short)|uniprotkb:Pathogen-specific membrane antigen(gene name synonym)|uniprotkb:TP_0971(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583253|imex:IM-9152-3337 author score:0.856875161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) ensemblbacteria:AAC65921(transcript)|ensemblbacteria:TP_0971(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR018470|rcsb pdb:2O6C|rcsb pdb:2O6D|rcsb pdb:2O6E|rcsb pdb:2O6F|rcsb pdb:3PJL|rcsb pdb:3PJN|refseq:WP_010882415.1|interpro:IPR038482 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0971; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:/paPIJaAH4qWKa1oNsKiHu2j2gE243276 intact-crc:2E5EF1E2D9508B1A|rigid:PmApOrlC4cKIFwpuDeLYfzxFawk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83084 uniprotkb:O83920 intact:EBI-1583278|ensemblbacteria:AAC65038 intact:EBI-1583271|ensemblbacteria:AAC65909|ensemblbacteria:AGN76119 psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:o83920_trepa(display_long)|uniprotkb:TP_0954(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583274|imex:IM-9152-3339 author score:0.85495975 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 ensemblbacteria:AAC65909(transcript)|ensemblbacteria:AGN76119(transcript)|ensemblbacteria:TP_0954(gene)|ensemblbacteria:TPANIC_0954(gene)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882398.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0954; PREY protein TP_0044|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 rogid:7E6WFoEXL4K6NndeG3HUG5gdzMA243276 intact-crc:6F96EC7BB6B7EDAD|rigid:tPdiCFgICsVJQw8SNnnFL4umPaU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83137 uniprotkb:O83589 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 intact:EBI-1583262|ensemblbacteria:AAC65554|ensemblbacteria:AGN75766 psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:o83589_trepa(display_long)|uniprotkb:TP_0580(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583265|imex:IM-9152-3338 author score:0.856136945 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 ensemblbacteria:AAC65554(transcript)|ensemblbacteria:AGN75766(transcript)|ensemblbacteria:TP_0580(gene)|ensemblbacteria:TPANIC_0580(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|refseq:WP_010882026.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0580; PREY protein TP_0099|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 rogid:xvraa/HrL33uUwTCJI8PxmuSwu8243276 intact-crc:E931581C0161CF0E|rigid:BUTLXsWHWa81uSkwEpUA+/5E24k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83359 uniprotkb:O83640 intact:EBI-1583288|ensemblbacteria:AAC65324|ensemblbacteria:AGN75537 intact:EBI-1583301|ensemblbacteria:AAC65607 psi-mi:o83359_trepa(display_long)|uniprotkb:TP_0339(locus name) psi-mi:syw_trepa(display_long)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:trpS(gene name)|psi-mi:trpS(display_short)|uniprotkb:trsA(gene name synonym)|uniprotkb:TP_0632(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583297|imex:IM-9152-3341 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65324(transcript)|ensemblbacteria:AGN75537(transcript)|ensemblbacteria:TP_0339(gene)|ensemblbacteria:TPANIC_0339(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|refseq:WP_010881787.1 ensemblbacteria:AAC65607(transcript)|ensemblbacteria:TP_0632(gene)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|interpro:IPR024109|refseq:WP_010882078.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0339; PREY protein TP_0632|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wZXcssM2lJreuLWZY57Fo6OASr0243276 rogid:i+LUDNbkZaxwLqc2AQr1bAEBBZQ243276 intact-crc:D7663E4E286194AE|rigid:dhfpBFhGBw2ZzSFhlw4IUdChBqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83359 uniprotkb:P96130 intact:EBI-1583288|ensemblbacteria:AAC65324|ensemblbacteria:AGN75537 intact:EBI-1583291|ensemblbacteria:AAC65656 psi-mi:o83359_trepa(display_long)|uniprotkb:TP_0339(locus name) psi-mi:recg_trepa(display_long)|uniprotkb:recG(gene name)|psi-mi:recG(display_short)|uniprotkb:TP_0687(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583284|imex:IM-9152-3340 author score:0.85149274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65324(transcript)|ensemblbacteria:AGN75537(transcript)|ensemblbacteria:TP_0339(gene)|ensemblbacteria:TPANIC_0339(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|refseq:WP_010881787.1 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR004609(DNA helicase, ATP-dependent, RecG)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR033454|ensemblbacteria:AAC65656(transcript)|ensemblbacteria:TP_0687(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417|refseq:WP_010882132.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0339; PREY protein TP_0687|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wZXcssM2lJreuLWZY57Fo6OASr0243276 rogid:QdgShP2vokjN3ZEytcn1OFR+oR0243276 intact-crc:FD3A82221C475B87|rigid:WugB5la5XkfT3ApQPDFxU+TFvdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83839 uniprotkb:O83359 intact:EBI-1583317|ensemblbacteria:AAC65845 intact:EBI-1583288|ensemblbacteria:AAC65324|ensemblbacteria:AGN75537 psi-mi:y869_trepa(display_long)|uniprotkb:TP_0869(locus name) psi-mi:o83359_trepa(display_long)|uniprotkb:TP_0339(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583313|imex:IM-9152-3343 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65845(transcript)|ensemblbacteria:TP_0869(gene)|refseq:WP_010882312.1 interpro:IPR020103|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65324(transcript)|ensemblbacteria:AGN75537(transcript)|ensemblbacteria:TP_0339(gene)|ensemblbacteria:TPANIC_0339(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|refseq:WP_010881787.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0339; PREY protein TP_0869|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GgRpxAbLBOBoLmeVcfxuPlg6cVo243276 rogid:wZXcssM2lJreuLWZY57Fo6OASr0243276 intact-crc:53488242AA72D78E|rigid:6XOmqgBVZPMqBsCMhyAtySF1NVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07893 uniprotkb:O83359 intact:EBI-1198815|intact:EBI-1582942|uniprotkb:Q7DFN7 intact:EBI-1583288|ensemblbacteria:AAC65324|ensemblbacteria:AGN75537 psi-mi:o07893_trepl(display_long)|uniprotkb:flgD(gene name)|psi-mi:flgD(display_short)|uniprotkb:FA889_03765(orf name) psi-mi:o83359_trepa(display_long)|uniprotkb:TP_0339(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583307|imex:IM-9152-3342 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005648(Flagellar hook capping protein)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882173.1 interpro:IPR020103|interpro:IPR006225(Pseudouridine synthase, RluD)|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65324(transcript)|ensemblbacteria:AGN75537(transcript)|ensemblbacteria:TP_0339(gene)|ensemblbacteria:TPANIC_0339(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|refseq:WP_010881787.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0339; PREY protein TP_0728|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jkKyM2jX2k6BQBpGyMhjjAdAUN8160 rogid:wZXcssM2lJreuLWZY57Fo6OASr0243276 intact-crc:EDAC934C2A6F251B|rigid:MkE4LG4thCnsSEwfhKdBaIQBcJg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83077 uniprotkb:O83256 intact:EBI-1582777|ensemblbacteria:AAC65029 intact:EBI-1583322|ensemblbacteria:AAC65216 psi-mi:y034_trepa(display_long)|uniprotkb:TP_0034(locus name) psi-mi:bioy_trepa(display_long)|uniprotkb:bioY(gene name)|psi-mi:bioY(display_short)|uniprotkb:TP_0228(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583325|imex:IM-9152-3344 author score:0.851443729 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65029(transcript)|ensemblbacteria:TP_0034(gene)|go:"GO:0007155"(cell adhesion)|go:"GO:0030001"(metal ion transport)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006129(Adhesin B)|interpro:IPR006128(Adhesion lipoprotein) interpro:IPR003784(BioY protein)|ensemblbacteria:TP_0228(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65216(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0228; PREY protein TP_0034|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KWhPDsTIcnWUpEkgiin3aHXNfo0243276 rogid:jLHmSiq6VFf0CvIsdtgcoe/yiPI243276 intact-crc:6853A2F3C73DA9FD|rigid:ZoS6EHVbtDntxKaL8grMJaR1EuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83147 uniprotkb:O83403 intact:EBI-1583331|ensemblbacteria:AAC65100|ensemblbacteria:AGN75328 intact:EBI-1583334|ensemblbacteria:AAC65372|ensemblbacteria:AGN75582 psi-mi:o83147_trepa(display_long)|uniprotkb:TP_0109(locus name) psi-mi:o83403_trepa(display_long)|uniprotkb:TP_0388(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583337|imex:IM-9152-3345 author score:0.851202599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004441(RNA methyltransferase TrmH, group 3)|interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|ensemblbacteria:AAC65100(transcript)|ensemblbacteria:AGN75328(transcript)|ensemblbacteria:TP_0109(gene)|ensemblbacteria:TPANIC_0109(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|refseq:WP_010881558.1|interpro:IPR029026|interpro:IPR029028 interpro:IPR013685(Polypeptide-transport-associated, FtsQ-type)|ensemblbacteria:AAC65372(transcript)|ensemblbacteria:AGN75582(transcript)|ensemblbacteria:TP_0388(gene)|ensemblbacteria:TPANIC_0388(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881836.1|interpro:IPR034746 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0388; PREY protein TP_0109|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4jhzBh20lX2enqR2C4ChM06aahI243276 rogid:nJIb1viIpWJEouXiymvdtYHvQDk243276 intact-crc:8E6A6299F2666A6A|rigid:ENzl9z/uHWzm5Hli+A6jWGLqWzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83847 uniprotkb:O83946 intact:EBI-1198567|intact:EBI-1583350|ensemblbacteria:AAC65840|ensemblbacteria:AGN76046 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:o83847_trepa(display_long)|uniprotkb:TP_0877(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583343|imex:IM-9152-3346 author score:0.849818837 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR037522|refseq:WP_010882320.1|ensemblbacteria:AAC65840(transcript)|ensemblbacteria:AGN76046(transcript)|ensemblbacteria:TP_0877(gene)|ensemblbacteria:TPANIC_0877(gene) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0877|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+QpyFXrHDZlRcsvImMZ76wZft48243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:505D1C2BC32E5278|rigid:QKQwWVwGElqBwV5gtYtGDwyLjxA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83127 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583364|imex:IM-9152-3348 author score:0.613784014 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0089|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 intact-crc:C81E56A68E1748A9|rigid:uOR+JFkWCCoI9RYeMAwToryUeLU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83130 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583355|imex:IM-9152-3347 author score:0.722763303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:4DBEBFF65FD7ED91|rigid:LpyHSVtRsHECr0s/RX5dt51MaBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83946 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583374|imex:IM-9152-3349 author score:0.611070882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0061|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:C8C0FD52398502CE|rigid:136NemHMgEYHGJV7tHLE1rSxZ44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83815 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198773|intact:EBI-1583380|ensemblbacteria:AAC65811|ensemblbacteria:AGN76013 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83815_trepa(display_long)|uniprotkb:TP_0843(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583383|imex:IM-9152-3350 author score:0.571844663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|refseq:WP_010882287.1|ensemblbacteria:AAC65811(transcript)|ensemblbacteria:AGN76013(transcript)|ensemblbacteria:TP_0843(gene)|ensemblbacteria:TPANIC_0843(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0843|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:h3WpgPV9/A/O8FQT3fN+2+aJjDo243276 intact-crc:9B5FE0EC0087FD05|rigid:emXJt9GV+ZBNltnDd63BKxyP54o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83411 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583395|imex:IM-9152-3352 author score:0.532016991 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 intact-crc:B91505B9082F0C65|rigid:BXawHXfEUZDAQjBTeW9QWzJoIwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83051 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583389|imex:IM-9152-3351 author score:0.551778666 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 intact-crc:990BAC874712F7D1|rigid:i5VvViRdUUPcD/AgspL/D36lbzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83195 uniprotkb:O83946 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583407|imex:IM-9152-3354 author score:0.406946508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:C327413D9AE88B79|rigid:xIEMf2993lm3rHCEJTFltk9YKyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83946 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583401|imex:IM-9152-3353 author score:0.453101882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:00A84F25EF8271AF|rigid:9GZSQMP7nAdfOUYXF+migDwkZHA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83542 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583419|imex:IM-9152-3356 author score:0.381238966 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:3B69371722126459|rigid:kfv2mBFcL/HsSQjXu3Iml4K+t7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83946 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583413|imex:IM-9152-3355 author score:0.387609851 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:EAC635C055E8A7E1|rigid:sbxyONt5CjhF5une8SyfDH3zH44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83804 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583428|imex:IM-9152-3357 author score:0.275100343 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:F01EA95E59E98FF3|rigid:eoDHTftA0cYp3AfRcmsK9ueT2cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:P21992 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583434|imex:IM-9152-3358 author score:0.242065998 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:B55F3CD0209E79AB|rigid:j8cFUbERdihK9iyTNJ1WtJoQ3Is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83946 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583446|imex:IM-9152-3360 author score:0.155433899 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:D024A8335C199D17|rigid:hSstiTUnewa77BxylNR0LyQSdF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83970 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583440|imex:IM-9152-3359 author score:0.23914829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:EF21BB40C7171840|rigid:J3mZYkEFvbZK7JSjeG9UF2eodDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83946 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583458|imex:IM-9152-3362 author score:0.14466971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:97E142D6E4ECDF6F|rigid:7nkTZgZjTcJtr0xM3FVyqUzy/WA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83946 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583452|imex:IM-9152-3361 author score:0.151520287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:384DF5FED04F0E47|rigid:QslKOjar0dULWyfKHWibjEQpEng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83946 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583470|imex:IM-9152-3364 author score:0.114477825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:21B0C9E97EDEB897|rigid:vSqSFqYoaoaAybAP690f8Mp9OmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83745 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583464|imex:IM-9152-3363 author score:0.129955374 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:99D98DBF8CA0C2BE|rigid:ARU6xXNnDJehF5BNLBmZIZ1t4hw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83574 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583476|imex:IM-9152-3365 author score:0.077518122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:7AA71BCE5FA73DD9|rigid:ZKqanU794oJPv8MNU0RF7Nuf1Vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83877 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583482|imex:IM-9152-3366 author score:0.067149073 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B213212DB3551A2A|rigid:yxteQxLGnmsFw2v+5s9OWlsdZqI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83282 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583494|imex:IM-9152-3368 author score:0.009657136 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:CFA1C912D7EF02A0|rigid:+ErxmHObxfFWA9tg82sCe8x5MfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83667 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583488|imex:IM-9152-3367 author score:0.042180739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:0E6102813F27BE11|rigid:l+wA/fuEKgwf2bK1ZdOmJkiCRhA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83946 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583500|imex:IM-9152-3369 author score:0.008011676 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:15BF31BF7E866F0D|rigid:aueE+/CjV5D5CNGRbsP1k54Y62U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83700 uniprotkb:O83293 intact:EBI-1198870|intact:EBI-1583519|ensemblbacteria:AAC65671 intact:EBI-1583512|ensemblbacteria:AAC65257 psi-mi:o83700_trepa(display_long)|uniprotkb:TP_0702(locus name) psi-mi:mtab_trepa(display_long)|uniprotkb:mtaB(gene name)|psi-mi:mtaB(display_short)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0269(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583515|imex:IM-9152-3371 author score:0.847509348 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|ensemblbacteria:AAC65671(transcript)|ensemblbacteria:TP_0702(gene) ensemblbacteria:AAC65257(transcript)|ensemblbacteria:TP_0269(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006467(MiaB-like tRNA modifying enzyme)|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR038135|refseq:WP_010881718.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0702; PREY protein TP_0269|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m+L0PIYpz1pXrbGDyvQbpbjJ9S4243276 rogid:R0+pKSsUrwJUTiyWqcbZFpkqooY243276 intact-crc:358DB52046F742F3|rigid:UnxGfwmVVXSxzkEDVDXyGUXSAYM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83946 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583506|imex:IM-9152-3370 author score:0.000688783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0981; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:A93281E2309B13B2|rigid:+xSbktsvequ4DJtmTlRoedAz4BY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83700 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198870|intact:EBI-1583519|ensemblbacteria:AAC65671 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83700_trepa(display_long)|uniprotkb:TP_0702(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583524|imex:IM-9152-3372 author score:0.003431943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|ensemblbacteria:AAC65671(transcript)|ensemblbacteria:TP_0702(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0702; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:m+L0PIYpz1pXrbGDyvQbpbjJ9S4243276 intact-crc:B4A5B87ABB6496DC|rigid:Mw2TpLcu4/o71RqYP10NY7LuKWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:P96130 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1583291|ensemblbacteria:AAC65656 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:recg_trepa(display_long)|uniprotkb:recG(gene name)|psi-mi:recG(display_short)|uniprotkb:TP_0687(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583530|imex:IM-9152-3373 author score:0.845941951 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR004609(DNA helicase, ATP-dependent, RecG)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR033454|ensemblbacteria:AAC65656(transcript)|ensemblbacteria:TP_0687(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417|refseq:WP_010882132.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0687; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:QdgShP2vokjN3ZEytcn1OFR+oR0243276 intact-crc:16453BB8E6F0BA94|rigid:OiH02Q0rSPGNMpwseyGifuK5P1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96130 uniprotkb:P16055 intact:EBI-1583291|ensemblbacteria:AAC65656 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:recg_trepa(display_long)|uniprotkb:recG(gene name)|psi-mi:recG(display_short)|uniprotkb:TP_0687(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583540|imex:IM-9152-3374 author score:0.720703806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR004609(DNA helicase, ATP-dependent, RecG)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR033454|ensemblbacteria:AAC65656(transcript)|ensemblbacteria:TP_0687(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417|refseq:WP_010882132.1 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0687; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QdgShP2vokjN3ZEytcn1OFR+oR0243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:1E0E49445DCB427F|rigid:i2H1d1EpOVLRoU4SWOFusj+917o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P96130 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583291|ensemblbacteria:AAC65656 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:recg_trepa(display_long)|uniprotkb:recG(gene name)|psi-mi:recG(display_short)|uniprotkb:TP_0687(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583546|imex:IM-9152-3375 author score:0.002420126 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR004609(DNA helicase, ATP-dependent, RecG)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR033454|ensemblbacteria:AAC65656(transcript)|ensemblbacteria:TP_0687(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417|refseq:WP_010882132.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0687; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:QdgShP2vokjN3ZEytcn1OFR+oR0243276 intact-crc:F903ACD2ECDE469C|rigid:KTWbds5GcKwGZsEBYcS9aKuiI+4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83327 uniprotkb:O83529 intact:EBI-1198543|intact:EBI-1583552|ensemblbacteria:AAC65292 intact:EBI-1583556|ensemblbacteria:AAC65504 psi-mi:pyrg_trepa(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:TP_0305(locus name)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym) psi-mi:murj_trepa(display_long)|uniprotkb:murJ(gene name)|psi-mi:murJ(display_short)|uniprotkb:mviN(gene name synonym)|uniprotkb:TP_0516(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583560|imex:IM-9152-3376 author score:0.842991347 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033828|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|refseq:WP_010881754.1|ensemblbacteria:AAC65292(transcript)|ensemblbacteria:TP_0305(gene)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0046872"(metal ion binding) ensemblbacteria:AAC65504(transcript)|ensemblbacteria:TP_0516(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015648"(lipid-linked peptidoglycan transporter activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0071555"(cell wall organization)|interpro:IPR004268(Virulence factor MVIN-like)|refseq:WP_010881965.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0516; PREY protein TP_0305|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:APACO59bBWxloqEuy3KSnF0gPp8243276 rogid:nis346XLPIX2bLxS6EIZ3KYYXTQ243276 intact-crc:E2A2A2DBAA2B21C6|rigid:QMA3xjMULGKvt3r3DRynFccO3vI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:O83318 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1583572|ensemblbacteria:AAC65274|ensemblbacteria:AGN75500 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:o83318_trepa(display_long)|uniprotkb:TP_0295(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583575|imex:IM-9152-3378 author score:0.842958076 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 ensemblbacteria:AAC65274(transcript)|ensemblbacteria:AGN75500(transcript)|ensemblbacteria:TP_0295(gene)|ensemblbacteria:TPANIC_0295(gene)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|interpro:IPR018485|refseq:WP_010881744.1|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0295; PREY protein TP_0640|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:RzfraT7mtIUw4msQ6qbTKlm6lTg243276 intact-crc:4E57328D3811ECB9|rigid:p+oZ3BHLoE14KhM2W5aHSOisgy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83529 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1583556|ensemblbacteria:AAC65504 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:murj_trepa(display_long)|uniprotkb:murJ(gene name)|psi-mi:murJ(display_short)|uniprotkb:mviN(gene name synonym)|uniprotkb:TP_0516(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583566|imex:IM-9152-3377 author score:0.733139527 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) ensemblbacteria:AAC65504(transcript)|ensemblbacteria:TP_0516(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015648"(lipid-linked peptidoglycan transporter activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0071555"(cell wall organization)|interpro:IPR004268(Virulence factor MVIN-like)|refseq:WP_010881965.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0516; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:nis346XLPIX2bLxS6EIZ3KYYXTQ243276 intact-crc:EA374ACD12A26EF2|rigid:N8848iE126y4B0her/xf8JGlYm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83711 uniprotkb:O83318 intact:EBI-1583585|ensemblbacteria:AAC65696 intact:EBI-1583572|ensemblbacteria:AAC65274|ensemblbacteria:AGN75500 psi-mi:y723_trepa(display_long)|uniprotkb:TP_0723(locus name) psi-mi:o83318_trepa(display_long)|uniprotkb:TP_0295(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583581|imex:IM-9152-3379 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65696(transcript)|ensemblbacteria:TP_0723(gene) ensemblbacteria:AAC65274(transcript)|ensemblbacteria:AGN75500(transcript)|ensemblbacteria:TP_0295(gene)|ensemblbacteria:TPANIC_0295(gene)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|interpro:IPR018485|refseq:WP_010881744.1|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0295; PREY protein TP_0723|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:zLNqGFiopfGtTqCzMXaUGR4NREg243276 rogid:RzfraT7mtIUw4msQ6qbTKlm6lTg243276 intact-crc:B72A982444FEFF45|rigid:17SpNOKshEejNzXhaUPJamgTZ3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83772 uniprotkb:O83048 intact:EBI-1583598|ensemblbacteria:AAC65758 intact:EBI-1198595|intact:EBI-1583590|ensemblbacteria:AAC65000 psi-mi:metk_trepa(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:TP_0794(locus name) psi-mi:dpo3b_trepa(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:DNA polymerase III subunit beta(gene name synonym)|uniprotkb:TP_0002(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583594|imex:IM-9152-3380 author score:0.841275091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65758(transcript)|ensemblbacteria:TP_0794(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|refseq:WP_010882239.1 interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022635|interpro:IPR022637|interpro:IPR022634|refseq:WP_010881452.1|ensemblbacteria:AAC65000(transcript)|ensemblbacteria:TP_0002(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0794; PREY protein TP_0002|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:q6ol4hEkalhVnwEicfLRE0iaSgU243276 rogid:4FZeat7yhkrv79CgJ0/2soG7qD4243276 intact-crc:29BEC3D79F952E55|rigid:K9+ZLc5SkL1e/scIsAnJcCYMlmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83772 uniprotkb:O83921 intact:EBI-1583598|ensemblbacteria:AAC65758 intact:EBI-1583604|ensemblbacteria:AAC65911 psi-mi:metk_trepa(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:TP_0794(locus name) psi-mi:y955_trepa(display_long)|uniprotkb:TP_0955(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583607|imex:IM-9152-3381 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65758(transcript)|ensemblbacteria:TP_0794(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|refseq:WP_010882239.1 ensemblbacteria:AAC65911(transcript)|ensemblbacteria:TP_0955(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0794; PREY protein TP_0955|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:q6ol4hEkalhVnwEicfLRE0iaSgU243276 rogid:5ro7xIDRkIgt0LXivsIFqg2MYso243276 intact-crc:C402D6EC2CFFE813|rigid:CanpjrgiAMtXLdZ7eWYQExjR9FA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83772 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1583598|ensemblbacteria:AAC65758 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:metk_trepa(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:TP_0794(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583613|imex:IM-9152-3382 author score:0.702321709 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) ensemblbacteria:AAC65758(transcript)|ensemblbacteria:TP_0794(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|refseq:WP_010882239.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0794; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:q6ol4hEkalhVnwEicfLRE0iaSgU243276 intact-crc:FF74FAF368613587|rigid:WjFpEKc24CqDfu0w80wFZO442wM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83373 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583629|imex:IM-9152-3384 author score:0.838203774 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0354; PREY protein TP_0097|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:89643F6F7532FC0F|rigid:5l5epVcSIR6t7vJ7DSlWOdVG8cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83772 uniprotkb:O83927 intact:EBI-1583598|ensemblbacteria:AAC65758 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:metk_trepa(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:TP_0794(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583619|imex:IM-9152-3383 author score:0.285262571 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65758(transcript)|ensemblbacteria:TP_0794(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|refseq:WP_010882239.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0794; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:q6ol4hEkalhVnwEicfLRE0iaSgU243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:519C1D3F297EDAC5|rigid:LuAnqEG8YjYbrMXotpuXkXOGx14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83373 uniprotkb:P21992 intact:EBI-1582513|ensemblbacteria:AAC65341 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583635|imex:IM-9152-3385 author score:0.401485451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0354; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:1814D815AE1CB29C|rigid:FsIxqtU4gcgasE7t3cb0AcUrsnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:O83854 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1583647|ensemblbacteria:AAC26574|ensemblbacteria:AGN76053 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:o83854_trepa(display_long)|uniprotkb:TP_0884(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583650|imex:IM-9152-3387 author score:0.837410218 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 interpro:IPR005495(Predicted permease YjgP/YjgQ)|ensemblbacteria:AAC26574(transcript)|ensemblbacteria:AGN76053(transcript)|ensemblbacteria:TP_0884(gene)|ensemblbacteria:TPANIC_0884(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0884|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:0NJ4SPoxnLNgc6nou7DoPdZDgLw243276 intact-crc:1B33C3DF03773629|rigid:Y0Ul4t/79PYya3b9NIxk/r8ZTBo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83373 uniprotkb:O83954 intact:EBI-1582513|ensemblbacteria:AAC65341 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583641|imex:IM-9152-3386 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0354; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:9A144CB368F12DD3|rigid:RkOq/gF7LDDpEZNYGhfqNQWKJFQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:O83486 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1583663|ensemblbacteria:AAC65467 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:y473_trepa(display_long)|uniprotkb:TP_0473(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583659|imex:IM-9152-3388 author score:0.731606157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 ensemblbacteria:AAC65467(transcript)|ensemblbacteria:TP_0473(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881922.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0473|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:Xo9b8/eVrjrXZxeEcrbobakqDg8243276 intact-crc:29133E78536646D9|rigid:8Mgi4WR9vAPaCP0QbDjP9MkBZkE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:P21992 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583674|imex:IM-9152-3390 author score:0.297143763 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:DA414EED11AFFF97|rigid:mAT7GtQsnFgzbDUhLK488Ak2GcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83511 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583668|imex:IM-9152-3389 author score:0.588228633 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 intact-crc:5FAF4A87323A24A4|rigid:sSKpbNih1MiDNnn1n4YYpuSZLM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83511 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583686|imex:IM-9152-3392 author score:0.225870273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 intact-crc:4464356668F160ED|rigid:jBs9Rp2EJs4kk+vy6uom1lnGu3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83511 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583680|imex:IM-9152-3391 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 intact-crc:6C0E00B856A21873|rigid:g83yupQ4dQrFpchITRYuPFy+5L8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:O83877 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583692|imex:IM-9152-3393 author score:0.162945204 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C9C721090159B613|rigid:KwwAJXZL8sksrwxAjGawJxzqNi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:O83954 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583704|imex:IM-9152-3395 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:87894D50C08A2FEF|rigid:VCWy2NjMzQssYZWcRPZz4C8rTN0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83511 uniprotkb:O83282 intact:EBI-1583654|ensemblbacteria:AAC65485|ensemblbacteria:AGN75688 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83511_trepa(display_long)|uniprotkb:TP_0498(locus name)|uniprotkb:Cell shape protein MreC(gene name synonym) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583698|imex:IM-9152-3394 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007221(Rod shape-determining protein MreC)|interpro:IPR042175|interpro:IPR042177|ensemblbacteria:AAC65485(transcript)|ensemblbacteria:AGN75688(transcript)|ensemblbacteria:TPANIC_0498(gene)|go:"GO:0008360"(regulation of cell shape)|ensemblbacteria:TP_0498(gene)|refseq:WP_010881947.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0498; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0UHsgI1ZY+qMVL2ifeKiKJOLsXo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:572E4F9A5AFB8A67|rigid:vXTyuy/vqqFUCcScaUxSnaRCG5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83890 uniprotkb:O83572 intact:EBI-1583720|ensemblbacteria:AAC65878 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583723|imex:IM-9152-3397 author score:0.760336541 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0561; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:37B02F39FE0FABA0|rigid:3hxcNZZ61y+qY+hYoVHkoXCljbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83950 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583710|imex:IM-9152-3396 author score:0.835405448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0561; PREY protein TP_0985|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:34D619EA5C237A99|rigid:3BJe3tps8lY1tS1qlTeQAXO3L/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83572 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583729|imex:IM-9152-3398 author score:0.596176028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0561; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:F0963EC2679AA4F3|rigid:GHNuyf6nvsTEXvAL5Uy5ncRcb28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83317 uniprotkb:O83790 intact:EBI-1582508|ensemblbacteria:AAC65273|ensemblbacteria:AGN75499 intact:EBI-1583741|ensemblbacteria:AAC65780 psi-mi:o83317_trepa(display_long)|uniprotkb:TP_0294(locus name) psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583745|imex:IM-9152-3400 author score:0.832351385 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|ensemblbacteria:AAC65273(transcript)|ensemblbacteria:AGN75499(transcript)|ensemblbacteria:TP_0294(gene)|ensemblbacteria:TPANIC_0294(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009165"(nucleotide biosynthetic process)|refseq:WP_010881743.1|interpro:IPR029057|interpro:IPR029099 interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0294|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:F8ONQ46scJ3Eu+h6lG8Ga5wZo/4243276 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 intact-crc:EA27BF563A60D40E|rigid:SNV+Moxilorx/6ZC8fFuQU5g7gM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83572 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583735|imex:IM-9152-3399 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0561; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:D316C1FE05DB0C43|rigid:3dYe6HFIaR+4x78yhSXg3zDpxRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83790 uniprotkb:P96131 intact:EBI-1583741|ensemblbacteria:AAC65780 intact:EBI-1583755|ensemblbacteria:AAC65347 psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:rl28_trepa(display_long)|uniprotkb:rpmB(gene name)|psi-mi:rpmB(display_short)|uniprotkb:rpl28(gene name synonym)|uniprotkb:TP_0362(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583751|imex:IM-9152-3401 author score:0.801083012 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 interpro:IPR001383(Ribosomal protein L28)|interpro:IPR034704|interpro:IPR026569|ensemblbacteria:AAC65347(transcript)|ensemblbacteria:TP_0362(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881810.1|interpro:IPR037147 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0362|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 rogid:77S9butCz8qvXZGwBHz17pmfbNk243276 intact-crc:EC9E03AA71446C8F|rigid:Kcv4lvHU2+eg/WUrCb9TOe2UOys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83790 uniprotkb:O83789 intact:EBI-1583741|ensemblbacteria:AAC65780 intact:EBI-1583765|ensemblbacteria:AAC65785 psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:y813_trepa(display_long)|uniprotkb:TP_0813(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583761|imex:IM-9152-3402 author score:0.720902339 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 ensemblbacteria:AAC65785(transcript)|ensemblbacteria:TP_0813(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0813|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 rogid:wL71DWwNtjOq2v6Bj7n8xyMImTI243276 intact-crc:A62AE8C0D7DAF43C|rigid:pWWtiaWDVzfc/lfFD89b5gIejO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83790 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1583741|ensemblbacteria:AAC65780 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583776|imex:IM-9152-3404 author score:0.376887301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 intact-crc:47E43D89CAC93D93|rigid:O406neTcep5+JUtaUtDrVBOUG5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83790 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1583741|ensemblbacteria:AAC65780 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583770|imex:IM-9152-3403 author score:0.692665394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 intact-crc:3BDF891AF8922904|rigid:kAB8V4U6e20iy7CbNUSugo5mciA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83790 uniprotkb:O83927 intact:EBI-1583741|ensemblbacteria:AAC65780 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583782|imex:IM-9152-3405 author score:0.225870273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:792381153D972669|rigid:BqeX4tMw8/94WfaVHoqyYQehNCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83790 uniprotkb:O83667 intact:EBI-1583741|ensemblbacteria:AAC65780 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583788|imex:IM-9152-3406 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:8D9649496EA794C4|rigid:EsGG27VsA4pInIm3FEX0SjJmIgo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83790 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583741|ensemblbacteria:AAC65780 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583800|imex:IM-9152-3408 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 intact-crc:E69A1617249670FE|rigid:m+AzlmqZRfhgo0w4x4zZ5erMdCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83790 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583741|ensemblbacteria:AAC65780 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:trxb_trepa(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:TP_0814(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583794|imex:IM-9152-3407 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR005982(Thioredoxin reductase)|ensemblbacteria:AAC65780(transcript)|ensemblbacteria:TP_0814(gene)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019430"(removal of superoxide radicals)|refseq:WP_010882258.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0814; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:+4m6GPQXnxPQ6Qh1TuBWi6affxE243276 intact-crc:8030B549AECCAFC7|rigid:7X3yXl2qwR8Pt2WDwAMfFZSDZu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83127 uniprotkb:O83868 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 intact:EBI-1583820|ensemblbacteria:AAC65853|ensemblbacteria:AGN76067 psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:o83868_trepa(display_long)|uniprotkb:TP_0898(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583816|imex:IM-9152-3410 author score:0.830433092 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 interpro:IPR014017(DNA helicase, UvrD-like, C terminal)|interpro:IPR000212(DNA helicase, UvrD/REP type)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR014016(Helicase, superfamily 1, UvrD-related)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|ensemblbacteria:AAC65853(transcript)|ensemblbacteria:AGN76067(transcript)|ensemblbacteria:TP_0898(gene)|ensemblbacteria:TPANIC_0898(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010882341.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0089; PREY protein TP_0898|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 rogid:cG68MihqYc9ysJ+MCzP9KUMBaRA243276 intact-crc:ADFB48124A14713A|rigid:Ky/9xSVrKQXhaTRa5ODTmDagJBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83401 uniprotkb:O83398 intact:EBI-1583806|ensemblbacteria:AAC65370 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:murf_trepa(display_long)|uniprotkb:murF(gene name)|psi-mi:murF(display_short)|uniprotkb:UDP-MurNAc-pentapeptide synthetase(gene name synonym)|uniprotkb:D-alanyl-D-alanine-adding enzyme(gene name synonym)|uniprotkb:TP_0386(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583810|imex:IM-9152-3409 author score:0.831532496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005863(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase)|ensemblbacteria:AAC65370(transcript)|ensemblbacteria:TP_0386(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008766"(UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0047480"(UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881834.1|interpro:IPR035911|interpro:IPR036565|interpro:IPR036615 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0386; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rfxEumOrxj37ygR4+vCjBl7k75c243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:86DC0CDD26A873AB|rigid:GgkNnDi+wSj6JRuvaNYenY9yDU0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83127 uniprotkb:O83969 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583826|imex:IM-9152-3411 author score:0.329171391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0089; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:E18FA6E58FCBD20D|rigid:KvBZ+m98hdgw3MGvuYGwQyYIfws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83127 uniprotkb:O83282 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583838|imex:IM-9152-3413 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0089; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:68F0123BB11912F0|rigid:Elyf+V51twFmvuWo3begQ7orARQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83127 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583832|imex:IM-9152-3412 author score:0.143215719 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0089; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 intact-crc:FC1ADB8D9F1B7FA6|rigid:oJzvCVnCCaXV8owZICC3bHy/MHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83127 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583361|ensemblbacteria:AAC65084|ensemblbacteria:AGN75308 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83127_trepa(display_long)|uniprotkb:TP_0089(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583844|imex:IM-9152-3414 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC65084(transcript)|ensemblbacteria:AGN75308(transcript)|ensemblbacteria:TP_0089(gene)|ensemblbacteria:TPANIC_0089(gene)|refseq:WP_010881538.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0089; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ZGQPwr2tMj1v2zRLa0dzcqkmKgk243276 intact-crc:0DC23AAC3F16DAE2|rigid:AwV1I+Kvq6B08xeLmXvTHpTVCQQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83738 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583850|imex:IM-9152-3415 author score:0.830030332 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:8271777A9DFF31E7|rigid:37U5T0cBE5ofhXEPeLfLasioOow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83960 uniprotkb:O83737 intact:EBI-1583870|ensemblbacteria:AAC26583 intact:EBI-1583105|ensemblbacteria:AAC65723 psi-mi:o83960_trepa(display_long)|uniprotkb:TP_0995(locus name) psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583873|imex:IM-9152-3417 author score:0.691028253 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC26583(transcript)|ensemblbacteria:TP_0995(gene)|interpro:IPR036890 interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0995|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e/7IeUNCDYEoLFDH9to3t6L3g3E243276 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 intact-crc:7019525CDE251CB1|rigid:PqFiKuXkpY0dqP7WF5fQcxyXjmE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83663 uniprotkb:O83737 intact:EBI-1583860|ensemblbacteria:AAC65631 intact:EBI-1583105|ensemblbacteria:AAC65723 psi-mi:csra_trepa(display_long)|uniprotkb:csrA(gene name)|psi-mi:csrA(display_short)|uniprotkb:TP_0657(locus name) psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583864|imex:IM-9152-3416 author score:0.723552637 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65631(transcript)|ensemblbacteria:TP_0657(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|interpro:IPR003751(Carbon storage regulator)|go:"GO:1902208"(regulation of bacterial-type flagellum assembly)|refseq:WP_010882102.1|interpro:IPR036107 interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0657|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xgEY9t+7VT0qj3fvWe/VSG+P/MA243276 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 intact-crc:B7012836E24E9E30|rigid:mr0GlEVmYuJt+LiBPtRWTu4DpYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83737 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1583105|ensemblbacteria:AAC65723 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583885|imex:IM-9152-3419 author score:0.508640202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 intact-crc:5B3631E3A1575876|rigid:Md3/6jqLv27MXZWMntLY7R8Qrgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83977 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1583534|ensemblbacteria:AAC65964 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583879|imex:IM-9152-3418 author score:0.64276713 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 intact-crc:53C74965710A9E63|rigid:JQt8/mhYfZNjH/z9leD8HKV9KkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83805 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583891|imex:IM-9152-3420 author score:0.434974615 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:55910B433C2DC042|rigid:dOFB/31PSFXc0iBJnwqfBLow16U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83982 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583903|imex:IM-9152-3422 author score:0.250456379 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:0E3272F71405519B|rigid:it1PXpfSvFtsHrJZcVE5G0bK/i0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83398 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583897|imex:IM-9152-3421 author score:0.250456379 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:D05E486E3A4794B8|rigid:jWcEp4Igi/ksDrAmrLtUlZY11ho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83099 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583909|imex:IM-9152-3423 author score:0.240327567 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:507197C673B6ABAC|rigid:fqm2YO956/Iwbqz8eq0VDpQ7enw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83767 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583921|imex:IM-9152-3425 author score:0.052154273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:A8505780F77D9E0F|rigid:WaUG2JZ1r/To9N3BefrPFX9wwV4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83413 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583915|imex:IM-9152-3424 author score:0.082007308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:07C067B7BBD1DD2C|rigid:plwVwMA2FpNEac3Z2jZoO0paCm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83282 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583933|imex:IM-9152-3427 author score:0.017919089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:B4F11298AA3C2011|rigid:zZ1gpWJD7IQn0dLMvoOiMJ6GUko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83737 uniprotkb:O83745 intact:EBI-1583105|ensemblbacteria:AAC65723 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583927|imex:IM-9152-3426 author score:0.043586496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:4DB035DE1E94D1BA|rigid:/xwaZLnrqv2SFGo8LrpfPJCkTDM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83737 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583105|ensemblbacteria:AAC65723 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583945|imex:IM-9152-3429 author score:0.001144704 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 intact-crc:5D1A7174DAEF93A9|rigid:9M3EHXF7UfJqIBp1rwIYfnomrfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83737 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583105|ensemblbacteria:AAC65723 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:fmt_trepa(display_long)|uniprotkb:fmt(gene name)|psi-mi:fmt(display_short)|uniprotkb:TP_0756(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583939|imex:IM-9152-3428 author score:0.014887052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005794(Methionyl-tRNA formyltransferase)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR044135|ensemblbacteria:AAC65723(transcript)|ensemblbacteria:TP_0756(gene)|go:"GO:0004479"(methionyl-tRNA formyltransferase activity)|refseq:WP_010882201.1|interpro:IPR036477|interpro:IPR037022|interpro:IPR041711 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0756; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:WXbtvhftJRnLZWUWGS+gCUp+uW8243276 intact-crc:53915AD7A4614D27|rigid:92g37e3E+ANzQErazipdNLywjbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83951 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1583959|ensemblbacteria:AAC65943|ensemblbacteria:AGN76150 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83951_trepa(display_long)|uniprotkb:TP_0986(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583964|imex:IM-9152-3431 author score:0.490282919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|ensemblbacteria:AAC65943(transcript)|ensemblbacteria:AGN76150(transcript)|ensemblbacteria:TP_0986(gene)|ensemblbacteria:TPANIC_0986(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882430.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0986; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:+oImbpfvCsrBVFWdzSyvOKeZpCU243276 intact-crc:C40351D6C1286B83|rigid:KpY89dnhTNgOz7H8ihZm2bJCa08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83895 uniprotkb:O83951 intact:EBI-1583951|ensemblbacteria:AAC65882 intact:EBI-1583959|ensemblbacteria:AAC65943|ensemblbacteria:AGN76150 psi-mi:flav_trepa(display_long)|uniprotkb:fldA(gene name)|psi-mi:fldA(display_short)|uniprotkb:TP_0925(locus name) psi-mi:o83951_trepa(display_long)|uniprotkb:TP_0986(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583955|imex:IM-9152-3430 author score:0.828817435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010087(Flavodoxin, short chain)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|ensemblbacteria:AAC65882(transcript)|ensemblbacteria:TP_0925(gene)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|refseq:WP_010882368.1|interpro:IPR029039 interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|ensemblbacteria:AAC65943(transcript)|ensemblbacteria:AGN76150(transcript)|ensemblbacteria:TP_0986(gene)|ensemblbacteria:TPANIC_0986(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882430.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0986; PREY protein TP_0925|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sjn5lih40bMPlilJS+bcmuaqFls243276 rogid:+oImbpfvCsrBVFWdzSyvOKeZpCU243276 intact-crc:55EC280ED5641D98|rigid:zJXUmCmHAYLtBhuIk8nRTmnLDy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83951 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1583959|ensemblbacteria:AAC65943|ensemblbacteria:AGN76150 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83951_trepa(display_long)|uniprotkb:TP_0986(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583976|imex:IM-9152-3433 author score:0.3001576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|ensemblbacteria:AAC65943(transcript)|ensemblbacteria:AGN76150(transcript)|ensemblbacteria:TP_0986(gene)|ensemblbacteria:TPANIC_0986(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882430.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0986; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:+oImbpfvCsrBVFWdzSyvOKeZpCU243276 intact-crc:19962803501A5E04|rigid:dzzlpTdVoEz9eXdl1PNbXTXPExY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83951 uniprotkb:O83969 intact:EBI-1583959|ensemblbacteria:AAC65943|ensemblbacteria:AGN76150 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83951_trepa(display_long)|uniprotkb:TP_0986(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583970|imex:IM-9152-3432 author score:0.329171391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|ensemblbacteria:AAC65943(transcript)|ensemblbacteria:AGN76150(transcript)|ensemblbacteria:TP_0986(gene)|ensemblbacteria:TPANIC_0986(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882430.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0986; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+oImbpfvCsrBVFWdzSyvOKeZpCU243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:BA73401FD1832DF4|rigid:9efYHcrC3my0OLeev6AzUyDyeIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83836 uniprotkb:O83487 intact:EBI-1583992|ensemblbacteria:AAC65827|ensemblbacteria:AGN76033 intact:EBI-1583995|ensemblbacteria:AAC65461 psi-mi:o83836_trepa(display_long)|uniprotkb:TP_0864(locus name) psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583988|imex:IM-9152-3435 author score:0.823498519 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|ensemblbacteria:AAC65827(transcript)|ensemblbacteria:AGN76033(transcript)|ensemblbacteria:TP_0864(gene)|ensemblbacteria:TPANIC_0864(gene)|refseq:WP_010882308.1|interpro:IPR036779 interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0864|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:U5uJqBTWMZMzPVYqM8Opx1Vsplg243276 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 intact-crc:124DF98F6BDF6D64|rigid:VUeEnkbYZ0twZNpy81AW7XJsUOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83951 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583959|ensemblbacteria:AAC65943|ensemblbacteria:AGN76150 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83951_trepa(display_long)|uniprotkb:TP_0986(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1583982|imex:IM-9152-3434 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR000620(Protein of unknown function DUF6, transmembrane)|ensemblbacteria:AAC65943(transcript)|ensemblbacteria:AGN76150(transcript)|ensemblbacteria:TP_0986(gene)|ensemblbacteria:TPANIC_0986(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882430.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0986; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:+oImbpfvCsrBVFWdzSyvOKeZpCU243276 intact-crc:DFD9B3577F64CA66|rigid:paJsgmVgrPNYvn7y4OM4xrxSbVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83523 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584014|ensemblbacteria:AAC65498 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:lepa_trepa(display_long)|uniprotkb:lepA(gene name)|psi-mi:lepA(display_short)|uniprotkb:TP_0510(locus name)|uniprotkb:Ribosomal back-translocase LepA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584010|imex:IM-9152-3437 author score:0.766004747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 interpro:IPR006297(GTP-binding protein LepA)|interpro:IPR013842(GTP-binding protein LepA, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65498(transcript)|ensemblbacteria:TP_0510(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR038363|refseq:WP_010881959.1|interpro:IPR027417|interpro:IPR035647|interpro:IPR035654|interpro:IPR041095 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0510|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:lXniJaC6m/GDSE+x7xGaF5w5KY0243276 intact-crc:3D551F307A59B433|rigid:2K61kInb2BMcnm8IZC8hV/zzF2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83776 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584000|imex:IM-9152-3436 author score:0.779058069 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0798|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:5549D81E0B8998AE|rigid:a8ZbAlfpg4kmLOQ+xNYTlCGsRJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83475 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584023|imex:IM-9152-3438 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0462|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:6C4645E64C56AA00|rigid:n5kbD/yUA4Bbr7XjXuX1nWmYQxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83502 uniprotkb:O83487 intact:EBI-1584038|ensemblbacteria:AAC65476|ensemblbacteria:AGN75680 intact:EBI-1583995|ensemblbacteria:AAC65461 psi-mi:o83502_trepa(display_long)|uniprotkb:TP_0489(locus name) psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584041|imex:IM-9152-3440 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|ensemblbacteria:AAC65476(transcript)|ensemblbacteria:AGN75680(transcript)|ensemblbacteria:TP_0489(gene)|ensemblbacteria:TPANIC_0489(gene)|refseq:WP_010881938.1|interpro:IPR036866 interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0489|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ajTuA2RY/JNCFpVcOmS30rDmRcc243276 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 intact-crc:08DD532BF9500193|rigid:WI+cXvp0DsG3st6PH6M1KNrHoWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83494 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584033|ensemblbacteria:AAC65470 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:y481_trepa(display_long)|uniprotkb:TP_0481(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584029|imex:IM-9152-3439 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 ensemblbacteria:AAC65470(transcript)|ensemblbacteria:TP_0481(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881930.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0481|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:4Tpphy/4l0/ReieCOfjrpYI7w3Y243276 intact-crc:5300F17B4FAA766E|rigid:dTGm6nqzkNd2QKMbFUDhTGPeamE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83657 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584060|imex:IM-9152-3442 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0651|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:127A3976621BAAA9|rigid:7AR/fB0f2kiQnjYUMob9+/N+EDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83544 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1584047|ensemblbacteria:AAC65519 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:vati2_trepa(display_long)|uniprotkb:atpI2(gene name)|psi-mi:atpI2(display_short)|uniprotkb:V-ATPase subunit I 2(gene name synonym)|uniprotkb:TP_0533(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584051|imex:IM-9152-3441 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|ensemblbacteria:AAC65519(transcript)|ensemblbacteria:TP_0533(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0533|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:fb0RMVb84Z3iOv1PFnWFVayWikI243276 intact-crc:203A181289AA42BE|rigid:o+O6W5zeVVyj6VhhP/6Ef9f2MBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83487 uniprotkb:O83772 intact:EBI-1583995|ensemblbacteria:AAC65461 intact:EBI-1583598|ensemblbacteria:AAC65758 psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:metk_trepa(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:TP_0794(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584066|imex:IM-9152-3443 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 ensemblbacteria:AAC65758(transcript)|ensemblbacteria:TP_0794(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|interpro:IPR022631|interpro:IPR022630|interpro:IPR022629|interpro:IPR022628|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022636|refseq:WP_010882239.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0794|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 rogid:q6ol4hEkalhVnwEicfLRE0iaSgU243276 intact-crc:69D7E5CFBDABA7FC|rigid:X/IHr88gpmkQdCTBGi1wXpLTf+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83815 uniprotkb:O83296 intact:EBI-1198773|intact:EBI-1583380|ensemblbacteria:AAC65811|ensemblbacteria:AGN76013 intact:EBI-1584078|ensemblbacteria:AAC65260 psi-mi:o83815_trepa(display_long)|uniprotkb:TP_0843(locus name) psi-mi:soj_trepa(display_long)|uniprotkb:TP_0272(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584081|imex:IM-9152-3445 author score:0.821042178 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|refseq:WP_010882287.1|ensemblbacteria:AAC65811(transcript)|ensemblbacteria:AGN76013(transcript)|ensemblbacteria:TP_0843(gene)|ensemblbacteria:TPANIC_0843(gene)|interpro:IPR036869 interpro:IPR025669|ensemblbacteria:AAC65260(transcript)|ensemblbacteria:TP_0272(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881721.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0272; PREY protein TP_0843|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:h3WpgPV9/A/O8FQT3fN+2+aJjDo243276 rogid:GF/zWY1aZplQ0XAwX8V+F8gIVrc243276 intact-crc:0F6C0EF34910B68C|rigid:8AKu+lIUCCvmouliW2g9Tec2TF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83487 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583995|ensemblbacteria:AAC65461 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y474_trepa(display_long)|uniprotkb:TP_0474(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584072|imex:IM-9152-3444 author score:0.001544474 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR026564|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|ensemblbacteria:AAC65461(transcript)|ensemblbacteria:TP_0474(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881923.1|interpro:IPR029072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0474; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:m8KN1yJaTDAwM9tiNC+phyyIjnU243276 intact-crc:EDD94893CD3FA500|rigid:TwkimFZXdMXQ1SIzPRJk4oMlUgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83296 uniprotkb:O83218 intact:EBI-1584078|ensemblbacteria:AAC65260 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:soj_trepa(display_long)|uniprotkb:TP_0272(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584087|imex:IM-9152-3446 author score:0.773202451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025669|ensemblbacteria:AAC65260(transcript)|ensemblbacteria:TP_0272(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881721.1|interpro:IPR027417 interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0272; PREY protein TP_0188|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GF/zWY1aZplQ0XAwX8V+F8gIVrc243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:02DEE9B70CAC4814|rigid:dUhR7ZFv3liNhLBQaDhzNUNJBeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83296 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1584078|ensemblbacteria:AAC65260 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:soj_trepa(display_long)|uniprotkb:TP_0272(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584097|imex:IM-9152-3447 author score:0.752756711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR025669|ensemblbacteria:AAC65260(transcript)|ensemblbacteria:TP_0272(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881721.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0272; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:GF/zWY1aZplQ0XAwX8V+F8gIVrc243276 intact-crc:ECBBF53725973D15|rigid:u3ItShiV53Lo6bIEOVWepxypgNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83296 uniprotkb:O83805 intact:EBI-1584078|ensemblbacteria:AAC65260 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:soj_trepa(display_long)|uniprotkb:TP_0272(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584103|imex:IM-9152-3448 author score:0.590241526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025669|ensemblbacteria:AAC65260(transcript)|ensemblbacteria:TP_0272(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881721.1|interpro:IPR027417 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0272; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GF/zWY1aZplQ0XAwX8V+F8gIVrc243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:DC586301707CA07D|rigid:Ol6mK6cf8m43L8QeaKc8sWuXe38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83296 uniprotkb:O83099 intact:EBI-1584078|ensemblbacteria:AAC65260 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:soj_trepa(display_long)|uniprotkb:TP_0272(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584109|imex:IM-9152-3449 author score:0.305843263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025669|ensemblbacteria:AAC65260(transcript)|ensemblbacteria:TP_0272(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881721.1|interpro:IPR027417 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0272; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GF/zWY1aZplQ0XAwX8V+F8gIVrc243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:DCD6897FAD8E3829|rigid:s3Ag3DLu/5vKdgrg6V3xEkNIsA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83656 uniprotkb:Q56346 intact:EBI-1584123|ensemblbacteria:AAC65623 intact:EBI-1584119|ensemblbacteria:AAC65644 psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:alr_trepa(display_long)|uniprotkb:alr(gene name)|psi-mi:alr(display_short)|uniprotkb:TP_0681(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584115|imex:IM-9152-3450 author score:0.820587046 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 interpro:IPR000821(Alanine racemase region)|interpro:IPR009006(Alanine racemase/group IV decarboxylase, C-terminal)|interpro:IPR011079(Alanine racemase, C-terminal)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR020622|ensemblbacteria:AAC65644(transcript)|ensemblbacteria:TP_0681(gene)|go:"GO:0008784"(alanine racemase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030632"(D-alanine biosynthetic process)|refseq:WP_012460586.1|interpro:IPR029066 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0681|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 rogid:n9srui1fP6pQRREQ3tHrRfm3xcw243276 intact-crc:DAC3D0BC549953FB|rigid:TEfpA2ZYgF+aGt3xaEyoNGUBEGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83656 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1584123|ensemblbacteria:AAC65623 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584128|imex:IM-9152-3451 author score:0.808091614 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0807|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 intact-crc:F8E5BF33C822ED12|rigid:OWSy0x5d61UzuTpmCAj11+RS8iA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83656 uniprotkb:O83738 intact:EBI-1584123|ensemblbacteria:AAC65623 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584138|imex:IM-9152-3452 author score:0.630912028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:7CD73EAD609996D4|rigid:vnlXr/UQB4fMwYw7u0HGnGBm/n8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83656 uniprotkb:O83099 intact:EBI-1584123|ensemblbacteria:AAC65623 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584144|imex:IM-9152-3453 author score:0.435062964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:14E07BF409061CEF|rigid:2sT1NMGmfDejRe3gSXP3JWyOw6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83656 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1584123|ensemblbacteria:AAC65623 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584150|imex:IM-9152-3454 author score:0.260414641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 intact-crc:9C7CA7C112C0AEB0|rigid:izpyMfjH8xMbxUa0XLialhUAO1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83656 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1584123|ensemblbacteria:AAC65623 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:ybey_trepa(display_long)|uniprotkb:ybeY(gene name)|psi-mi:ybeY(display_short)|uniprotkb:TP_0650(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584156|imex:IM-9152-3455 author score:0.216510799 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR023091|interpro:IPR020549|interpro:IPR002036(Protein of unknown function UPF0054)|ensemblbacteria:AAC65623(transcript)|ensemblbacteria:TP_0650(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882095.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0650; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:KMRYpese/+L9el4gm7v+S/5CBEw243276 intact-crc:796CFCEE90A28CDD|rigid:0GaiU6H7Z1k7wWJS6opgl9MPzgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83642 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584170|imex:IM-9152-3456 author score:0.820181337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:62BA13F6F169CF60|rigid:EBe+FY6gND5jaear1cMPKpMAEOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83527 uniprotkb:O83642 intact:EBI-1581703|ensemblbacteria:AAC65502 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584176|imex:IM-9152-3457 author score:0.753759829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:8809AED721391C5C|rigid:WWWQfA1DI1mUZy9sOaFbuK4HqpY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83474 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584182|imex:IM-9152-3458 author score:0.71343339 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0461|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 intact-crc:33BA35ABE6DF7B8B|rigid:8K8AFgelWHhmds6W4HQUA94qIuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83738 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584191|imex:IM-9152-3459 author score:0.681971646 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:537E1E7088DD3CBE|rigid:jj7qL++GLMxa1XOXV4awFuKEj+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83909 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584201|imex:IM-9152-3460 author score:0.581932482 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:B71BC48377BC31AF|rigid:iF80mJ5fVRRqKdDlTRmn31/03R0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:Q08255 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584216|imex:IM-9152-3462 author score:0.562162731 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:4A0567635F23946D|rigid:GG4aASxQda7kKL3hHsdBTodtMHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83642 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584210|imex:IM-9152-3461 author score:0.575368509 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:EFF5136A029379DC|rigid:NecCiVmOsv8KtK0/qYil7rQ/MfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83542 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584226|imex:IM-9152-3463 author score:0.535503686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:E371A79F15C05F17|rigid:N3PyitBcE86Q01aaH3QRieHN1VA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83627 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584232|imex:IM-9152-3464 author score:0.501910434 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:456F8FBEC82C1E76|rigid:6CO9w2yf8Y5hvM2ISDiK6uKqW6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83532 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584244|imex:IM-9152-3465 author score:0.46160248 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:1B7CCA1EB12815A8|rigid:67xg9VDCFscJBWOdSawin/mgUUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83642 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584250|imex:IM-9152-3467 author score:0.438815344 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:92CE2216EB8FA217|rigid:3tvvqa0O6co3rNfdN3hM21koSTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83642 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584259|imex:IM-9152-3468 author score:0.357862712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:7747392347F1995A|rigid:iVzy9d+JU1tp0FF2yWUVbUdaWOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83282 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584271|imex:IM-9152-3469 author score:0.017919089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:255562D651FB0819|rigid:z5zKJkIeubkBi+T+7iLP8Ddvir4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83642 uniprotkb:O83667 intact:EBI-1584162|ensemblbacteria:AAC65609 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584265|imex:IM-9152-3466 author score:0.076128626 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:47AB96421714349B|rigid:0LZX08qlc/i6lXQgit/bfGFRC+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83642 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1584162|ensemblbacteria:AAC65609 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:dnlj_trepa(display_long)|uniprotkb:ligA(gene name)|psi-mi:ligA(display_short)|uniprotkb:lig(gene name synonym)|uniprotkb:TP_0634(locus name)|uniprotkb:"Polydeoxyribonucleotide synthase [NAD(+)]"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584277|imex:IM-9152-3470 author score:0.014887052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001357(BRCT)|interpro:IPR018239|interpro:IPR004150(NAD-dependent DNA ligase, OB-fold)|interpro:IPR001679(NAD-dependent DNA ligase)|interpro:IPR013839(NAD-dependent DNA ligase, adenylation)|interpro:IPR013840(NAD-dependent DNA ligase, N-terminal)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR010994(RuvA domain 2-like)|ensemblbacteria:AAC65609(transcript)|ensemblbacteria:TP_0634(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003911"("DNA ligase (NAD+) activity")|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882080.1|interpro:IPR036420 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0634; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:p3S0sYYfRcSS4MQNc6EMhUNs/tM243276 intact-crc:B3D22329DE6FD0DD|rigid:7jv/bIKgMIaj5wsrHTIFSAtRInI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83950 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584298|imex:IM-9152-3473 author score:0.428732183 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:053B457BED8E5D33|rigid:vlMKT7ZLNrnyndZJ5iQ32FUzXSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83909 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584283|imex:IM-9152-3471 author score:0.819056433 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:8636BF8785924691|rigid:jM0DqvoEOWzGX49sCnxrz+sfiDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83717 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1584293|ensemblbacteria:AAC65703|ensemblbacteria:AGN75909 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83717_trepa(display_long)|uniprotkb:TP_0735(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584289|imex:IM-9152-3472 author score:0.509010031 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR017896|interpro:IPR006004("Glutamate synthase (NADPH), homotetrameric")|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR023753|ensemblbacteria:AAC65703(transcript)|ensemblbacteria:AGN75909(transcript)|ensemblbacteria:TP_0735(gene)|ensemblbacteria:TPANIC_0735(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010882180.1|interpro:IPR028261|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0735|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:G49VLaWESe0ywK6wQ33JQEyEMzg243276 intact-crc:6B702920B8218701|rigid:f2EYIQGT7Xu68VfkQEBu+kWRqcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83950 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584310|imex:IM-9152-3475 author score:0.384408238 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:5749A5B6972C6696|rigid:BuU5yUI+oiBg3d3EIkJCevHadRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83752 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584304|imex:IM-9152-3474 author score:0.395008288 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:D07CBA1D347A79A5|rigid:E+xqvRYqLLsVP5RtdcgYleLmCUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83950 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584316|imex:IM-9152-3476 author score:0.366808939 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:E10A52834330ACD2|rigid:WgJpeqh5y4GKZNwHMTrREDeGtK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83627 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584322|imex:IM-9152-3477 author score:0.364415477 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:DBAB8539A509E12B|rigid:bWb/5S4XypEqWoNZedtXNmjjI2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83572 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584328|imex:IM-9152-3478 author score:0.318775282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:6AFF8FB29C951816|rigid:3BJe3tps8lY1tS1qlTeQAXO3L/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83950 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584349|imex:IM-9152-3481 author score:0.24075496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:10117D56A2F3E83F|rigid:c7iy/zIG5RjOtQvBnvBoS+y7HSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83950 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584343|imex:IM-9152-3480 author score:0.304602663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:D8D32D7CC42AF5D2|rigid:oHnYeyaUlY7wokHMEkb3bpEf8uk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83950 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584334|imex:IM-9152-3479 author score:0.304602663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:BE89982B10DAA1E1|rigid:ELrOHiGmOAtMIz6DgO1/X/5CbMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83305 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584361|imex:IM-9152-3483 author score:0.16339937 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:34DC563EDF0DCD5E|rigid:qvIu0e8s0piOM0utLE9hHLXzYGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83982 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584355|imex:IM-9152-3482 author score:0.208762961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:6121CCA31CD857BD|rigid:KFY1xD0Ex8RxAd18yZBoYxAed0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83950 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584376|imex:IM-9152-3485 author score:0.142499369 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:B49A5DD80BEF93D6|rigid:egVv8awIDgL7T3Y/d5vhqN0us48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83398 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584367|imex:IM-9152-3484 author score:0.159752337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:F39BFE5A78B0E9AA|rigid:9MoU+c4XL2bEHH1EmNEPUdRj1ek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83969 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584382|imex:IM-9152-3486 author score:0.129839992 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:45CB960DC1FA669F|rigid:ejQS/pm+a2ulVnclnLFm14Eo78U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83877 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584388|imex:IM-9152-3487 author score:0.053576308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B005CFCA9128FFF6|rigid:yHXnCG8DNnhnEys5EDtPC7yjUvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83413 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584394|imex:IM-9152-3488 author score:0.048371069 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:F0DD117BB627C830|rigid:MA/JQnydrdMYQvkF5I1s/2xbnjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83950 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584400|imex:IM-9152-3489 author score:0.044785961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:25263F549A47F570|rigid:Qvf2T1qBbk3XkRx36N7Zd8ZX2qA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83745 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584406|imex:IM-9152-3490 author score:0.034991186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:CA97D6D515326257|rigid:Rl2sa+hZsZ4VtvvTc25kSkdYVJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83950 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584412|imex:IM-9152-3491 author score:0.030357676 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:812C5A58AFEFB950|rigid:ZrNR7uM4VV91kSf4ZBIFGBOkuo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83950 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584424|imex:IM-9152-3493 author score:0.008525287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:B37A2A13B2BE67DD|rigid:OayPN6e3YdlUmv0Ol8rtVpXd4aU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83950 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584418|imex:IM-9152-3492 author score:0.010275142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:2BDC5450E99F1EF8|rigid:JRcIXvwXQhfENHIWvhyudv2Lki8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83070 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584436|imex:IM-9152-3495 author score:0.818766824 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:3F663C56304323B9|rigid:EorL6ugxtBpcmAD313CHREpsWC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83950 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583714|ensemblbacteria:AAC65942 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584430|imex:IM-9152-3494 author score:0.000508764 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0985; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 intact-crc:81884125FD494FF2|rigid:1LF3UR+0xPrlScS8O8dIpBdHdCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83413 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584442|imex:IM-9152-3496 author score:0.791947271 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:9C4C9A9AEFCC5DBB|rigid:bEx8HKduQCVKNZhziveRFgcOnJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83130 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584448|imex:IM-9152-3497 author score:0.46448804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:4C3CF332B596EAA0|rigid:BcK08+SnPVpVSziSVENHay6XYlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83944 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198284|intact:EBI-1584454|ensemblbacteria:AAC65934|ensemblbacteria:AGN76143 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83944_trepa(display_long)|uniprotkb:TP_0979(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584457|imex:IM-9152-3498 author score:0.453224115 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR015991(Deoxyribonuclease, TatD Mg-dependent, prokaryote)|interpro:IPR032466|refseq:WP_010882423.1|ensemblbacteria:AAC65934(transcript)|ensemblbacteria:AGN76143(transcript)|ensemblbacteria:TP_0979(gene)|ensemblbacteria:TPANIC_0979(gene)|go:"GO:0004536"(deoxyribonuclease activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0979|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:VwV7BKYNFGpEJRQwHw4dm+E5jPk243276 intact-crc:491CBD17523427D7|rigid:C+4ZGeOApSd0W9OhYeuKIlLxbjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96115 uniprotkb:O83413 intact:EBI-1198311|uniprotkb:O83197|intact:EBI-1581520|ensemblbacteria:AAC65150 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:ruvb_trepa(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:TP_0162(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584463|imex:IM-9152-3499 author score:0.439917418 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|refseq:WP_010881609.1|ensemblbacteria:AAC65150(transcript)|ensemblbacteria:TP_0162(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0162|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pKRvyji0nd7AkF5U2AAlQB988W0243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:BC7417A627585D5F|rigid:PD1S4yLTGeImCmuWaMZZf1FzBnA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83195 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584469|imex:IM-9152-3500 author score:0.439174389 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:EA818A33A0589AEC|rigid:vjsKacLNpHMXraGlsyhU0YaycEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83588 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584475|imex:IM-9152-3501 author score:0.426696522 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0579|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 intact-crc:4577CF855D242988|rigid:HgepPtbHwzM8DADhzbg7nFoifBo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83637 uniprotkb:O83413 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584481|imex:IM-9152-3502 author score:0.420123936 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CDEE946000E515A3|rigid:A5xrUUOAsWJrUI+lhvR2u603kn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83413 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584487|imex:IM-9152-3503 author score:0.407065557 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6090449A6FC071DF|rigid:q47pAjNLiin6QzN/OOeo7UD0dA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83051 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584493|imex:IM-9152-3504 author score:0.40058407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 intact-crc:7A464CDAD57548AD|rigid:ZLHl9JcsVhNX1vKZDuhIXbezkEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83089 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584499|imex:IM-9152-3505 author score:0.394137185 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:751FFDBD1FC2BF18|rigid:VDDrW1gR72z1XHsnZSDeCeZvjRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:P21992 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584505|imex:IM-9152-3506 author score:0.392271896 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:D5B4ED3D580158B1|rigid:WLR0RRDtcgvtFk8ea3/7l1jey8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83413 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584517|imex:IM-9152-3508 author score:0.370406579 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6E8108CD02599C3D|rigid:SwMO90I3Hk1YSfTimVnGKJxKdWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83105 uniprotkb:O83413 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584511|imex:IM-9152-3507 author score:0.387726942 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:7F61CFDB710D143C|rigid:xSMz3T2uc2fnTAaI7umTIi/T+eM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:P45685 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584523|imex:IM-9152-3509 author score:0.344041698 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:BB98A6AD1FCC53C3|rigid:UhuK3fMqlqVCG4SdbA58wrMLY8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83542 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584529|imex:IM-9152-3510 author score:0.337991683 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:67F5CB98FC079C60|rigid:B02A1OjWmNk0rs7v9ZQ4QIBhjdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83398 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584541|imex:IM-9152-3512 author score:0.178320258 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:5B06E8562E504290|rigid:iEWxieN6D3s1Q6zabsb+MUaTFEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83804 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584535|imex:IM-9152-3511 author score:0.239238053 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:B36E201D3F8AD7EC|rigid:ZwfwyD5HGmlwght734i6Q0F7l04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83574 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584553|imex:IM-9152-3514 author score:0.065099694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:9E57BDF880411CD8|rigid:vXgDQvWGWXVQgb3V6LdR2u96wbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83413 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584547|imex:IM-9152-3513 author score:0.096759491 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:658C69BA758D09E8|rigid:l7/vqJI5cNaRAH5/B8+MscZam0w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83413 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584565|imex:IM-9152-3516 author score:0.038056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:0338DC4852FCD39A|rigid:mGDqbXBs1A88i5zSD53UI398NkI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83877 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584559|imex:IM-9152-3515 author score:0.042200672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:480BE0C54B5B13CF|rigid:40dXc6w6g4dp5+wyEjaPXhqYsTw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83745 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584577|imex:IM-9152-3518 author score:0.035084397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:A4EA5D0C06F258E8|rigid:EnT/yw6ZPTw0+C5V5Z4f3e6vKQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83667 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584571|imex:IM-9152-3517 author score:0.035207311 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:FD7217E9D0A5EB04|rigid:GF0F1CYMzgj2iU/ruu6WXIts3Ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83413 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584583|imex:IM-9152-3519 author score:0.023788044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:D6259E3DF959EB09|rigid:EZszCg/CX4pBZdiY5dGmu4U1uiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83282 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584589|imex:IM-9152-3520 author score:0.008015597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:1C41240AFAFC6B1C|rigid:sapvGgW8kUWPPQQaN0GOhJJFDUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83954 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584595|imex:IM-9152-3521 author score:0.006647957 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4CC5693606F38D33|rigid:riS20E7tVEKr0gWuYD/07sPmqvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83958 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584601|imex:IM-9152-3522 author score:0.000502456 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0398; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6258FF7B08AAA36F|rigid:4h0Ozj4RaTzjzZCX/+RYjdYPWEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83163 uniprotkb:O83709 intact:EBI-1584611|ensemblbacteria:AAC65118 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y126_trepa(display_long)|uniprotkb:TP_0126(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584607|imex:IM-9152-3523 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65118(transcript)|ensemblbacteria:TP_0126(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR011250(Outer membrane protein, beta-barrel) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0711; PREY protein TP_0126|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciO/q3x+ouX8MJuNI0cs1fC4ZcY243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:801CDD2620FDEA70|rigid:nl6W30+aTPEw5Npy5FumLUEU8ns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83120 uniprotkb:O83429 intact:EBI-1584635|ensemblbacteria:AAC65076|ensemblbacteria:AGN75300 intact:EBI-1584628|ensemblbacteria:AAC65402|ensemblbacteria:AGN75609 psi-mi:o83120_trepa(display_long)|uniprotkb:TP_0081(locus name) psi-mi:o83429_trepa(display_long)|uniprotkb:TP_0414(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584631|imex:IM-9152-3525 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016166(FAD-binding, type 2)|interpro:IPR002346(Molybdopterin dehydrogenase, FAD-binding)|go:"GO:0071949"(FAD binding)|ensemblbacteria:AAC65076(transcript)|ensemblbacteria:AGN75300(transcript)|ensemblbacteria:TP_0081(gene)|ensemblbacteria:TPANIC_0081(gene)|go:"GO:0016491"(oxidoreductase activity)|refseq:WP_010881530.1|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318 interpro:IPR001463("Sodium:alanine symporter")|ensemblbacteria:AAC65402(transcript)|ensemblbacteria:AGN75609(transcript)|ensemblbacteria:TP_0414(gene)|ensemblbacteria:TPANIC_0414(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015655"("alanine:sodium symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881862.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0081; PREY protein TP_0414|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xvLHNtL8mQ0UNRGebrcKSlMs3aY243276 rogid:sMlFdWAkjglgnHCFAkTeld2vd4A243276 intact-crc:E431B25777F128E6|rigid:b+3Iy83iMUPYJljvR6Li2lMNCt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83076 uniprotkb:O83255 intact:EBI-1584623|ensemblbacteria:AAC65028|ensemblbacteria:AGN75254 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 psi-mi:o83076_trepa(display_long)|uniprotkb:TP_0033(locus name) psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584619|imex:IM-9152-3524 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009793(Protein of unknown function DUF1361)|ensemblbacteria:AAC65028(transcript)|ensemblbacteria:AGN75254(transcript)|ensemblbacteria:TP_0033(gene)|ensemblbacteria:TPANIC_0033(gene) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0033; PREY protein TP_0227|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l34Vl9mSbOJI553PMZCImIl3bSk243276 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 intact-crc:CBD2F5C151F8F974|rigid:rEoy2YIPwU1yssR/Rp0TUlzRon8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83375 uniprotkb:O83822 intact:EBI-1584648|ensemblbacteria:AAC65342|ensemblbacteria:AGN75553 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:o83375_trepa(display_long)|uniprotkb:TP_0356(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584644|imex:IM-9152-3526 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000504(RNA recognition motif, RNP-1)|ensemblbacteria:AAC65342(transcript)|ensemblbacteria:AGN75553(transcript)|ensemblbacteria:TP_0356(gene)|ensemblbacteria:TPANIC_0356(gene)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0356; PREY protein TP_0850|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4S0j9WEberZBuaqHgLtl8D9Szqs243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:9AA32D83CC89EA95|rigid:kJZBwixNIA8sVrNVhNKNIP3bKQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88138 uniprotkb:O83825 intact:EBI-1584653|ensemblbacteria:AAC65107|ensemblbacteria:AAC65117|ensemblbacteria:AGN75353|ensemblbacteria:AGN75336 intact:EBI-1584656|ensemblbacteria:AAC65818|ensemblbacteria:AGN76023 psi-mi:o88138_trepa(display_long)|uniprotkb:TP_0117(locus name)|uniprotkb:TP_0131(locus name) psi-mi:o83825_trepa(display_long)|uniprotkb:TP_0853(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584659|imex:IM-9152-3527 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65107(transcript)|ensemblbacteria:AAC65117(transcript)|ensemblbacteria:AGN75336(transcript)|ensemblbacteria:AGN75353(transcript)|ensemblbacteria:TP_0117(gene)|ensemblbacteria:TP_0131(gene)|ensemblbacteria:TPANIC_0117(gene)|ensemblbacteria:TPANIC_0131(gene)|refseq:WP_010881566.1 interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|ensemblbacteria:AAC65818(transcript)|ensemblbacteria:AGN76023(transcript)|ensemblbacteria:TP_0853(gene)|ensemblbacteria:TPANIC_0853(gene)|go:"GO:0005524"(ATP binding)|refseq:WP_010882297.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0131; PREY protein TP_0853|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E3rUnbUNBCn31ZBDe9ej3SZrZRo243276 rogid:wX45nqwyqRi3MQXtIXF/WyGW0Uc243276 intact-crc:08D483A665C1CEE6|rigid:Twwy8XF19hlbrY43Pn6M4iza2CA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:P29725 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1584669|ensemblbacteria:AAC65966 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:bmp_trepa(display_long)|uniprotkb:tpn39b(gene name)|psi-mi:tpn39b(display_short)|uniprotkb:TP_1016(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584665|imex:IM-9152-3528 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR027304|ensemblbacteria:AAC65966(transcript)|ensemblbacteria:TP_1016(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005886"(plasma membrane)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|refseq:WP_010882460.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0917; PREY protein TP_1016|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:uJFI1E6/KT6v4GH4XwOJ3xo+QBg243276 intact-crc:F596578B5EE130E7|rigid:i7aWd4j2PgzUqkCvOoVRPvv7YY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O84000 uniprotkb:O83795 intact:EBI-1584675|ensemblbacteria:AAC26591 intact:EBI-1584682|ensemblbacteria:AAC65791|ensemblbacteria:AGN75993 psi-mi:y1037_trepa(display_long)|uniprotkb:TP_1037(locus name) psi-mi:o83795_trepa(display_long)|uniprotkb:TP_0823(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584678|imex:IM-9152-3529 author score:0.818173934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004254(Hly-III related)|interpro:IPR005744(HylII)|ensemblbacteria:AAC26591(transcript)|ensemblbacteria:TP_1037(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis) interpro:IPR002742(Desulfoferrodoxin, ferrous iron-binding region)|rcsb pdb:1Y07|ensemblbacteria:AAC65791(transcript)|ensemblbacteria:AGN75993(transcript)|ensemblbacteria:TP_0823(gene)|ensemblbacteria:TPANIC_0823(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016491"(oxidoreductase activity)|refseq:WP_010882267.1|interpro:IPR036073 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0823; PREY protein TP_1037|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:r+uWDoYer8CosA2mHSlK0VJXjfM243276 rogid:wgXwdoTB60hg+5FDzdhF6TOFXWI243276 intact-crc:A0DE6A6B4618B63A|rigid:pV3L+AvZSZaQ4obWONx5XUhHhzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83761 uniprotkb:O83634 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584696|imex:IM-9152-3531 author score:0.778142926 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:62995FAAA45C1B2F|rigid:2oQq/ndtjWWRZC4w4eLeMXQ7TUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83761 uniprotkb:O83361 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584690|imex:IM-9152-3530 author score:0.814523688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:0E9B7D076AE4DB0C|rigid:63kiut33wSY554gdz35m/wSH91Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83761 uniprotkb:O83565 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584705|imex:IM-9152-3532 author score:0.730690337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:8EBCEA855EA2E07E|rigid:xhLDrI14/BSFxwXZuD/eNz/Ycy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83761 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584711|imex:IM-9152-3533 author score:0.655542333 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 intact-crc:5BEFF0CF9D829712|rigid:vhD6pNAoR8jg3kTK+ppJIQvQLOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83761 uniprotkb:O83531 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584717|imex:IM-9152-3534 author score:0.404526381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:7153B1D13D43FFB9|rigid:45PmrdVoqHCKkRu1RefA+rdhg9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83761 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584723|imex:IM-9152-3535 author score:0.338788497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 intact-crc:E3AEEBCB2BF02611|rigid:SbXLVw6m2LzXIIVOvN4hegdIo20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83761 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584729|imex:IM-9152-3536 author score:0.201199229 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0782; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 intact-crc:10EEA744F94CF370|rigid:JPykqXNLb84bqF0/0Wht4NyqKZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83591 uniprotkb:O83931 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584738|imex:IM-9152-3537 author score:0.814385103 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:5AC0D4C5C9CD5595|rigid:qoZe8sO4Qtn2eg0Z22MshZdAdTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83362 uniprotkb:O83591 intact:EBI-1584754|ensemblbacteria:AAC65330 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:kcy_trepa(display_long)|uniprotkb:cmk(gene name)|psi-mi:cmk(display_short)|uniprotkb:Cytidine monophosphate kinase(gene name synonym)|uniprotkb:TP_0342(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584750|imex:IM-9152-3539 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011892(Cytidylate kinase, putative)|ensemblbacteria:AAC65330(transcript)|ensemblbacteria:TP_0342(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0036430"(CMP kinase activity)|go:"GO:0036431"(dCMP kinase activity)|interpro:IPR027417|interpro:IPR011994(Cytidylate kinase region) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0342|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1643bjgy8ivHZTvvgo/QzspBeqw243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:C090FE88537A5414|rigid:eCvY45VeHQdu9BshL9TQ0Dv/Bl0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83195 uniprotkb:O83591 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584744|imex:IM-9152-3538 author score:0.741479976 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:5087FEE3B3959DD2|rigid:iOZInDswZi/4CSQIw64CBUQBA6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83591 uniprotkb:O83383 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584760|imex:IM-9152-3540 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0368|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:6338448153153CEF|rigid:oEcDmiEdumQDl/vBYrENrDUNUMA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56342 uniprotkb:O83591 intact:EBI-1584773|uniprotkb:Q56341|ensemblbacteria:AAC65648 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:mgla_trepa(display_long)|uniprotkb:mglA(gene name)|psi-mi:mglA(display_short)|uniprotkb:TP_0685(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584769|imex:IM-9152-3541 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR015862(ABC transporter, galactose import, MglA)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65648(transcript)|ensemblbacteria:TP_0685(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043211"(ABC-type carbohydrate transporter activity)|interpro:IPR027417|refseq:WP_010882130.1 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0685|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wRRyBbzqePD5yl6Y20iKqBDJEI8243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:2942947BE763782E|rigid:PRqsA8TEJApjR/cST7uSTSxpHYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83591 uniprotkb:O83746 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 intact:EBI-1582804|ensemblbacteria:AAC65728 psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:ftsh_trepa(display_long)|uniprotkb:ftsH(gene name)|psi-mi:ftsH(display_short)|uniprotkb:TP_0765(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584788|imex:IM-9152-3543 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 ensemblbacteria:AAC65728(transcript)|ensemblbacteria:TP_0765(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0005524"(ATP binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR000642(Peptidase M41)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0765|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 rogid:zWGHvScW/wuy/c/u+Jp7mBjrhHQ243276 intact-crc:2D06B2DCFC823EAC|rigid:/q1CT3Qv+erpJCir9rFYnStxKYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83591 uniprotkb:O83696 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 intact:EBI-1584779|ensemblbacteria:AAC65667 psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:y698_trepa(display_long)|uniprotkb:TP_0698(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584782|imex:IM-9152-3542 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 interpro:IPR024471|ensemblbacteria:TP_0698(gene)|ensemblbacteria:AAC65667(transcript)|refseq:WP_010882143.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0698|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 rogid:OLeXKHwCSKBENO8w2RtFOz8xww0243276 intact-crc:3DA13702507AD3E6|rigid:uNQDn2i2pvHt/kYoGb48ei8AWPg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83591 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584800|imex:IM-9152-3545 author score:0.461148506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:45279A843AFEA5D9|rigid:I+OFFu8RqsADuq+p4bYvqnUqUd4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83591 uniprotkb:O83412 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584794|imex:IM-9152-3544 author score:0.581085474 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:805665B23C84B7DC|rigid:/WbBnJg3d2uPXWn330UnJAsAVXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83591 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584806|imex:IM-9152-3546 author score:0.266162028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:0B9DFC866F751D6B|rigid:QUSecAIMv5bxUs+kPHKC9cXN3ME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83591 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584812|imex:IM-9152-3547 author score:0.26240127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:4F928E239F164FE0|rigid:R4/U4R5mamfwkE6FZfD5UolcrFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83591 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584818|imex:IM-9152-3548 author score:0.14339739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:85378361E58095B0|rigid:+dFzAt2HutHP74gfnNBfW1uGd54 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83591 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584824|imex:IM-9152-3549 author score:0.015834394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:E29EADFD8CC1C193|rigid:7lSoQDsK0DNv7zsJP+bQyGfhWCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83591 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584830|imex:IM-9152-3550 author score:0.001799819 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0582; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:BF3DA8D262C5143F|rigid:rsTKpIe8OYqesrSZ6Csq5KZZZT4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83050 uniprotkb:O83980 intact:EBI-1584836|ensemblbacteria:AAC65005 intact:EBI-1584843|ensemblbacteria:AAC65968 psi-mi:y004_trepa(display_long)|uniprotkb:TP_0004(locus name) psi-mi:sya_trepa(display_long)|uniprotkb:alaS(gene name)|psi-mi:alaS(display_short)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_1017(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584839|imex:IM-9152-3551 author score:0.814134444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007922(Protein of unknown function DUF721)|ensemblbacteria:AAC65005(transcript)|ensemblbacteria:TP_0004(gene)|refseq:WP_010881454.1 interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|ensemblbacteria:AAC65968(transcript)|ensemblbacteria:TP_1017(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010882461.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1017; PREY protein TP_0004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IxAoquYRvbXKT9V9t6ETfHG8dHo243276 rogid:82IYaAPutLlnuQc0U+VLvDbYTR0243276 intact-crc:C768B9B828DDFBD9|rigid:jpv+BZtBoVwinp1Ull/arskGnZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83793 uniprotkb:O83150 intact:EBI-1584868|ensemblbacteria:AAC65788 intact:EBI-1584865|ensemblbacteria:AAC65103|ensemblbacteria:AGN75331 psi-mi:y818_trepa(display_long)|uniprotkb:TP_0818(locus name) psi-mi:o83150_trepa(display_long)|uniprotkb:TP_0112(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584861|imex:IM-9152-3553 author score:0.814134444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65788(transcript)|ensemblbacteria:TP_0818(gene) interpro:IPR025660|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|ensemblbacteria:AAC65103(transcript)|ensemblbacteria:AGN75331(transcript)|ensemblbacteria:TP_0112(gene)|ensemblbacteria:TPANIC_0112(gene)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|refseq:WP_010881561.1|interpro:IPR038765 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0112; PREY protein TP_0818|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QnxKmMr04H37/A461aRYWlKKgdE243276 rogid:INxv+oKU1Yag2NOh2MIKXBibj6o243276 intact-crc:DC54791A4A03EBE7|rigid:cXSe8n2xSOq80SfoEa5bl12kN7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83736 uniprotkb:O83628 intact:EBI-1584849|ensemblbacteria:AAC65722|ensemblbacteria:AGN75929 intact:EBI-1584852|ensemblbacteria:AAC65602 psi-mi:o83736_trepa(display_long)|uniprotkb:TP_0755(locus name) psi-mi:y619_trepa(display_long)|uniprotkb:TP_0619(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584855|imex:IM-9152-3552 author score:0.814134444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|ensemblbacteria:AAC65722(transcript)|ensemblbacteria:AGN75929(transcript)|ensemblbacteria:TP_0755(gene)|ensemblbacteria:TPANIC_0755(gene) interpro:IPR024471|ensemblbacteria:AAC65602(transcript)|ensemblbacteria:TP_0619(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0755; PREY protein TP_0619|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+V25qa+sulKE7zbturQ36mU7oPk243276 rogid:Uu0BCAc+U8Kg1DCfvszCdAprE2o243276 intact-crc:C00CEDB55B543FCE|rigid:f0R6xjfw8HysXB6gYRNzLbrRbp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O83530 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584877|imex:IM-9152-3554 author score:0.813821848 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:DE333932CD8F6B03|rigid:9h8bnZv0SFaD1WrLzhJ4rsG/qOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83361 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584886|imex:IM-9152-3555 author score:0.728561587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:0798DF16688B20E4|rigid:qVwREtBRea9cpFIEfyaJ4wN2r44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83317 uniprotkb:O83530 intact:EBI-1582508|ensemblbacteria:AAC65273|ensemblbacteria:AGN75499 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83317_trepa(display_long)|uniprotkb:TP_0294(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584892|imex:IM-9152-3556 author score:0.549112536 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|ensemblbacteria:AAC65273(transcript)|ensemblbacteria:AGN75499(transcript)|ensemblbacteria:TP_0294(gene)|ensemblbacteria:TPANIC_0294(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009165"(nucleotide biosynthetic process)|refseq:WP_010881743.1|interpro:IPR029057|interpro:IPR029099 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0294|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:F8ONQ46scJ3Eu+h6lG8Ga5wZo/4243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:96374A3C114D6E3C|rigid:I3f+x9VsnnXYaSn7ZlvPingxCwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83530 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584898|imex:IM-9152-3557 author score:0.532127736 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:4C2A0AEBF5F4D2EC|rigid:9FzRCPYxG6f4uiZD93P75KUXY4w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83913 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584904|imex:IM-9152-3558 author score:0.529432482 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:E0E0DEB9FAFECBC8|rigid:1aQTbFqwqMOsHSgca8ow56iwRuc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83530 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584910|imex:IM-9152-3559 author score:0.511852308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:5E0D4FE93EC20DB7|rigid:Hmzz5mIi4ioIzdsABEYbMsz+Z/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83738 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584922|imex:IM-9152-3561 author score:0.423031747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:9821C84E7F17B3E7|rigid:hkv9VU8caCpQjkwcBMta5YLruuw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:Q08255 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584916|imex:IM-9152-3560 author score:0.46854557 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:D2E32D3AC34A15AC|rigid:qoGLFkBlO4/U5OpakxkWhruP90o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83565 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584928|imex:IM-9152-3562 author score:0.351924929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:42769C4F2565A109|rigid:yw2hathgvWzZbeHQ896i87l1TQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83670 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584934|imex:IM-9152-3563 author score:0.345809367 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:165DCCF22D6F4274|rigid:z2/W7H2a84s0Q1fwx+9ylbUIcpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83709 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584940|imex:IM-9152-3564 author score:0.276761915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:182C17016599C5A8|rigid:XgsmrgbzXdCGF4vPH2iPGhJceCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83530 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584946|imex:IM-9152-3565 author score:0.270135991 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:15C9030E4F493B0A|rigid:lPjvpmYx88JXPJy3KvJu26FxE+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83530 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584958|imex:IM-9152-3567 author score:0.219665632 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:F347305145D687ED|rigid:Z+7UWJENrODD6zskDXQySBX8gXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83530 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584952|imex:IM-9152-3566 author score:0.250641622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:550270B41842E622|rigid:ghWK3eyBrXiSKuknR0xbmVWoZsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:P21992 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584964|imex:IM-9152-3568 author score:0.21960443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:3D246992AE252061|rigid:9YsO2ZvX3xjcaHAeXhT6NqwMbvU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83312 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584970|imex:IM-9152-3569 author score:0.142439107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:29AEC7DF72F58EB2|rigid:IqgyaPNDwd/yesM0P4hHyjy/GQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83877 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584976|imex:IM-9152-3570 author score:0.089190509 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:00A2B017BA2A7A7D|rigid:S9yR7/sOak0w2yFBC/AEga8JDmM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83767 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584988|imex:IM-9152-3572 author score:0.036406795 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:98132AA5118CC44E|rigid:Evr1zzT2k+WO7FOaNcnOqy8LwTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83667 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584982|imex:IM-9152-3571 author score:0.053551303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C82490A26402FDE3|rigid:0SmL775ixPBNJm4DqMtsd6DB++U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83530 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1584873|ensemblbacteria:AAC65505 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1584994|imex:IM-9152-3573 author score:0.012373649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 intact-crc:CEE8AA535787DD94|rigid:LmlnpcIYdgIkBKc6zvDHARGlWls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83530 uniprotkb:O83954 intact:EBI-1584873|ensemblbacteria:AAC65505 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:ruvc_trepa(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)|uniprotkb:TP_0517(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585000|imex:IM-9152-3574 author score:0.010270127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|ensemblbacteria:AAC65505(transcript)|ensemblbacteria:TP_0517(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|refseq:WP_010881966.1|interpro:IPR036397 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0517; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LamJS8Z302e3RAxCjYO51681hTQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:85CD92DD86277526|rigid:fdJHP2tx4qQa7tLL3NZNzociOEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83161 uniprotkb:O83106 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585009|imex:IM-9152-3575 author score:0.813553361 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:235D4BE4EFF00A59|rigid:bYBH780k9GH9htQSIM3DuFKvDtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83051 uniprotkb:O83161 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585015|imex:IM-9152-3576 author score:0.7149395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:63BDE5245655E3E1|rigid:HZIo9HtloMBXdusIb+EfjK4hoTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83161 uniprotkb:O83447 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 intact:EBI-1585025|ensemblbacteria:AAC65420 psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:y432_trepa(display_long)|uniprotkb:TP_0432(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585021|imex:IM-9152-3577 author score:0.68738031 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 ensemblbacteria:AAC65420(transcript)|ensemblbacteria:TP_0432(gene)|refseq:WP_010881880.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0432|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 rogid:C9WqS8T1hASpueWfFwanX4vNYXE243276 intact-crc:14371AB000C0B12A|rigid:0oedUU9D2W4zj8OJd7MUpNVWZrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83161 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585030|imex:IM-9152-3578 author score:0.675694563 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0795|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:5640084A92A0C0D1|rigid:hG6AmxoJzINoC2MyniwtPTjTv68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83161 uniprotkb:O83702 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585039|imex:IM-9152-3579 author score:0.626838015 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:1D35F16783B66231|rigid:EjgbBoA8YFo0Hum1bzFeKe/1fHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83161 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585045|imex:IM-9152-3580 author score:0.594852717 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:2122FAD89C4615A6|rigid:IknqMUU5DFA0YEg53d0Rait+Ijg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83161 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585051|imex:IM-9152-3581 author score:0.481603579 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:FCBDE91191CCFEAE|rigid:qRaGzLZcW/6mjm2MROmBSHGsPEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83161 uniprotkb:O83099 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585057|imex:IM-9152-3582 author score:0.356306874 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:1D446CEA280EADA7|rigid:s/CnPJS8CO0hGVTtMROWfc0HhCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83161 uniprotkb:O83574 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585063|imex:IM-9152-3583 author score:0.159487671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:0B5BBC2A33D60265|rigid:awqJpjx8pazrT53d77jbi6sQd5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83161 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585075|imex:IM-9152-3585 author score:0.052129895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:7C7D6E6027FC1A9D|rigid:ct48dlj93T86qPZu6jI3x7Ym9e4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83161 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585069|imex:IM-9152-3584 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:20F73C6BED2DBE0A|rigid:TVws4MW0moTEj/oYiCPrT3H6WOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83161 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585081|imex:IM-9152-3586 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0124; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:7CE9B2DB7B06676D|rigid:16ITkmqTW6yY44psRIAMYbC+lGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83402 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585087|imex:IM-9152-3587 author score:0.813261027 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:109954144CC02AF9|rigid:PcRygnyjiYzfIGvwv0OxmxkIKXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83264 uniprotkb:O83402 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585093|imex:IM-9152-3588 author score:0.747072819 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_0236|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:B40E444091C036A4|rigid:cvdB3Z/0iTAOeZWz+3OC4y1t3MQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83284 uniprotkb:O83402 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585103|imex:IM-9152-3589 author score:0.747072819 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_0260|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:893F740D2FB4B411|rigid:n8U2BLnP/I/hnxfWRFYGmdLgrmg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83402 uniprotkb:O83572 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585118|imex:IM-9152-3591 author score:0.508270364 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:AFE5ECE115ED516B|rigid:KA71c7SuBGLKUQH8QQcI8xjChrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83402 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585112|imex:IM-9152-3590 author score:0.610411036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:A23901CBCF6A3597|rigid:vBkFgvc9gm6hagEwU8bQDtVGRxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83084 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1583278|ensemblbacteria:AAC65038 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585130|imex:IM-9152-3593 author score:0.813163982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0044; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 intact-crc:1D9001CFE5A92AFA|rigid:IX3k+rMlqU2GmGp2JTP1TVo/Lcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83402 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582548|ensemblbacteria:AAC65371|ensemblbacteria:AGN75581 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83402_trepa(display_long)|uniprotkb:TP_0387(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585124|imex:IM-9152-3592 author score:0.007442587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|ensemblbacteria:AAC65371(transcript)|ensemblbacteria:AGN75581(transcript)|ensemblbacteria:TP_0387(gene)|ensemblbacteria:TPANIC_0387(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051301"(cell division)|refseq:WP_010881835.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0387; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:s4fQz1lY7jHpOitn5KzfO0Z2BrQ243276 intact-crc:F0ABB5AE6D1632AD|rigid:GzQgvJiWT0ij9L78ROAYntvuAdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83084 uniprotkb:O83261 intact:EBI-1583278|ensemblbacteria:AAC65038 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585136|imex:IM-9152-3594 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0044; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:84409771BBBEB357|rigid:aV3iyUiPx5/HZYq+ml8qBhI5r9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83436 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585157|imex:IM-9152-3597 author score:0.734955669 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0421; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:25E730F8CA0FF661|rigid:eBunjSa2vszGRGgdr3pVZPagjj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83436 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585151|imex:IM-9152-3596 author score:0.811997615 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0421; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:5B278C51F019B170|rigid:Wo6IDxfE8RuRWNErIp13HfWc0/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83084 uniprotkb:O83958 intact:EBI-1583278|ensemblbacteria:AAC65038 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585142|imex:IM-9152-3595 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0044; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7511CBAABB2A3574|rigid:DHQ3B0pcz6sLTpL+E7rupsvb4zU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83436 uniprotkb:O83709 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585163|imex:IM-9152-3598 author score:0.526113444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0421; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:959B2ED284621DD6|rigid:Ft+FHE1OBRIhqL5tk1ECIMN3VD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83436 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585169|imex:IM-9152-3599 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0421; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:8C8BDFADFF74C788|rigid:kXHjWeHPIKnkHcHqhyOBguIe494 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83070 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585175|imex:IM-9152-3600 author score:0.810716513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:65DE0DEE489FA03E|rigid:VnkhiUtua5z9R4s88pkE9t3ut6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83412 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585181|imex:IM-9152-3601 author score:0.744479673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:348BD5529BB2EF2D|rigid:aB6zR6Ypn222WtTtmxvjdu/7brw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83761 uniprotkb:O83927 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585187|imex:IM-9152-3602 author score:0.69582695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0782|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:18DDC800AD8CB4C0|rigid:XJU3NaneXFXJ+FpoxDu+KHW/CMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07885 uniprotkb:O83927 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585193|imex:IM-9152-3603 author score:0.644679417 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:13C1C42D1AA5989F|rigid:zhgt3I3xl7/+YWoickv+GHZuQ9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83881 uniprotkb:O83927 intact:EBI-1199028|intact:EBI-1585205|ensemblbacteria:AAC65862|ensemblbacteria:AGN76079 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83881_trepa(display_long)|uniprotkb:TP_0911(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585208|imex:IM-9152-3605 author score:0.551020377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029025|interpro:IPR004683(FlhB-like)|interpro:IPR006135(Type III secretion exporter)|refseq:WP_010882354.1|ensemblbacteria:AAC65862(transcript)|ensemblbacteria:AGN76079(transcript)|ensemblbacteria:TP_0911(gene)|ensemblbacteria:TPANIC_0911(gene)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0911|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5jI5N/SVRQzQ66Jqtz9tsAS0IFg243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:92DDCB9AF42D1147|rigid:zScjMVbmjfq8ps8rFlulC9KpUB8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83847 uniprotkb:O83927 intact:EBI-1198567|intact:EBI-1583350|ensemblbacteria:AAC65840|ensemblbacteria:AGN76046 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83847_trepa(display_long)|uniprotkb:TP_0877(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585199|imex:IM-9152-3604 author score:0.577062151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR037522|refseq:WP_010882320.1|ensemblbacteria:AAC65840(transcript)|ensemblbacteria:AGN76046(transcript)|ensemblbacteria:TP_0877(gene)|ensemblbacteria:TPANIC_0877(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0877|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+QpyFXrHDZlRcsvImMZ76wZft48243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:948315A02D9544DF|rigid:AWx/se/tn8ZxXwNgjDe5tKH47BI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83336 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198975|intact:EBI-1585224|ensemblbacteria:AAC65305 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y314_trepa(display_long)|uniprotkb:TP_0314(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585220|imex:IM-9152-3607 author score:0.446561195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR024471|ensemblbacteria:AAC65305(transcript)|ensemblbacteria:TP_0314(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0314|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:rjZuIwOLYsidiK8cJHZrG52uw9o243276 intact-crc:31991F20226137B1|rigid:Aa4hFyC6mdgCpfKpI8VrAdLwQTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83927 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585214|imex:IM-9152-3606 author score:0.484310966 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:49CD0653CFC8A643|rigid:WkAR4fvY6MdIHsZX10NjCIN3+7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83927 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585232|imex:IM-9152-3608 author score:0.439917418 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0772|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:1E652786A64DE636|rigid:2wgX3+F8YwOaystRgmiySzANp4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83732 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585250|imex:IM-9152-3611 author score:0.413579556 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 intact-crc:0FF758EE5379D837|rigid:STitghvV6ScSehj+dIHv2+7tu5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83195 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585238|imex:IM-9152-3609 author score:0.439174389 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:0156A9C10ADD6074|rigid:5EBKAZg7nFlFgH9640d3jPWmfHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83264 uniprotkb:O83927 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585244|imex:IM-9152-3610 author score:0.426696522 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0236|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:8D0D39D0B79305E9|rigid:Dp2K1wGjhF1Bk5RgwGFlMjwSwPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83051 uniprotkb:O83927 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585265|imex:IM-9152-3613 author score:0.40058407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:0FBC20995F8CD60E|rigid:440DrCqRaIlXna5+RGPQreIOiVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:P21992 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585259|imex:IM-9152-3612 author score:0.403223796 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:FDB209F1D1A8814E|rigid:bse5DVc8omTXjIL/K62qCJ7s5Oc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83927 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585271|imex:IM-9152-3614 author score:0.394137185 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:9EC8DE4FB5474580|rigid:TFDPJR1EfWAhucwuk1dDPvIIyBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83068 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585280|imex:IM-9152-3615 author score:0.356293189 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:AAAAAA555683634A|rigid:sAvJHAbE5sZlSN459uoypJNSHKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83311 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585289|imex:IM-9152-3616 author score:0.291597783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:E3B2141A3140DE38|rigid:Djpbn0Q/Fz5LEv4dy8nLPLhtZzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83927 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585301|imex:IM-9152-3618 author score:0.254245908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:DD3EE0E2D58368E3|rigid:JW8sFxYNcYVI1jm/ERqa6E+izOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83752 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585295|imex:IM-9152-3617 author score:0.27519872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:C5552B4699F35722|rigid:WZ5pdWu10pfL357P+fcCFbEl2hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83804 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585313|imex:IM-9152-3620 author score:0.239238053 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:F7B068B81A6248F0|rigid:qe7U3AdGFkJVlIyL4xXPhDZtQtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83982 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585319|imex:IM-9152-3621 author score:0.128903272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:48FFD8944E8579A7|rigid:SuFhX/meUupk+dDG+ZlM/AJ92Yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83738 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585307|imex:IM-9152-3619 author score:0.244172372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:F637D6349231F5E5|rigid:L3kWd9R3TFcYyjdk+3btv49HrDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83312 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585325|imex:IM-9152-3622 author score:0.096759491 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:8E5B4A48DF08F370|rigid:Nx3pnbH0BC59hZbVqJKxFtUaAbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83927 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585337|imex:IM-9152-3624 author score:0.042200672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:00117BCF6DABEE71|rigid:GUw9Dr8qtQ/QEwzFYp0nNeBR0bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83927 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585331|imex:IM-9152-3623 author score:0.081494095 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:822E338E6F4FDC39|rigid:ANByK7VZPkrrVIqhJD28Hmp/XzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83927 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585343|imex:IM-9152-3625 author score:0.034763354 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:B8B4E93C304B8C1C|rigid:1blenbXeFWUr7Declv1kd5/R/Yw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83767 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585349|imex:IM-9152-3626 author score:0.023788044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:8240B3503537A6E0|rigid:HmN/f1rEUCmXkDtEBRskF4FjZ7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83927 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585355|imex:IM-9152-3627 author score:0.000396026 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0961; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:B371EE4FAA4A14F8|rigid:77MxkEPvjaoQ66PmWj1y+HsKRAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83107 uniprotkb:O83399 intact:EBI-1585371|ensemblbacteria:AAC65061 intact:EBI-1585361|ensemblbacteria:AAC65368 psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:rsmh_trepa(display_long)|uniprotkb:rsmH(gene name)|psi-mi:rsmH(display_short)|uniprotkb:TP_0384(locus name)|uniprotkb:mraW(gene name synonym)|uniprotkb:"16S rRNA m(4)C1402 methyltransferase"(gene name synonym)|uniprotkb:"rRNA (cytosine-N(4)-)-methyltransferase RsmH"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585374|imex:IM-9152-3629 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 interpro:IPR002903(Bacterial methyltransferase)|interpro:IPR023397|ensemblbacteria:AAC65368(transcript)|ensemblbacteria:TP_0384(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070475"(rRNA base methylation)|go:"GO:0071424"("rRNA (cytosine-N4-)-methyltransferase activity")|refseq:WP_010881832.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0384; PREY protein TP_0068|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 rogid:L2XXcYQsWhDzfixNAAe9holqhhk243276 intact-crc:2037D0028D21FE5D|rigid:l2NQWmEg8KIDefxn6gyUkk0fUHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83399 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1585361|ensemblbacteria:AAC65368 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:rsmh_trepa(display_long)|uniprotkb:rsmH(gene name)|psi-mi:rsmH(display_short)|uniprotkb:TP_0384(locus name)|uniprotkb:mraW(gene name synonym)|uniprotkb:"16S rRNA m(4)C1402 methyltransferase"(gene name synonym)|uniprotkb:"rRNA (cytosine-N(4)-)-methyltransferase RsmH"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585365|imex:IM-9152-3628 author score:0.810506462 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002903(Bacterial methyltransferase)|interpro:IPR023397|ensemblbacteria:AAC65368(transcript)|ensemblbacteria:TP_0384(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070475"(rRNA base methylation)|go:"GO:0071424"("rRNA (cytosine-N4-)-methyltransferase activity")|refseq:WP_010881832.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0384; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:L2XXcYQsWhDzfixNAAe9holqhhk243276 intact-crc:17ECE60D210A5FD0|rigid:/tKKxzkf40xFzrdORpg7C0sD1Jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83474 uniprotkb:O83275 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585386|imex:IM-9152-3631 author score:0.810085908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0461; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:194420137B44D4C0|rigid:sNy7vYuGWvFREsi0KsW/mF/GWEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83399 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1585361|ensemblbacteria:AAC65368 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:rsmh_trepa(display_long)|uniprotkb:rsmH(gene name)|psi-mi:rsmH(display_short)|uniprotkb:TP_0384(locus name)|uniprotkb:mraW(gene name synonym)|uniprotkb:"16S rRNA m(4)C1402 methyltransferase"(gene name synonym)|uniprotkb:"rRNA (cytosine-N(4)-)-methyltransferase RsmH"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585380|imex:IM-9152-3630 author score:0.600969391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR002903(Bacterial methyltransferase)|interpro:IPR023397|ensemblbacteria:AAC65368(transcript)|ensemblbacteria:TP_0384(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070475"(rRNA base methylation)|go:"GO:0071424"("rRNA (cytosine-N4-)-methyltransferase activity")|refseq:WP_010881832.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0384; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:L2XXcYQsWhDzfixNAAe9holqhhk243276 intact-crc:EA39DBA88C7437CC|rigid:0LP4cLHeaws5byLUr2OYKXgdj9k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83474 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585398|imex:IM-9152-3633 author score:0.634928983 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0461; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 intact-crc:44E00A009C36ACAB|rigid:jyZaRarwjRqgelnf6h8n9kZLNvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83474 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585392|imex:IM-9152-3632 author score:0.753764808 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0461; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 intact-crc:7AAB9A722D43FE52|rigid:xP996bIjY0Qr62eoxuJKqYWQDfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83474 uniprotkb:O83282 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585410|imex:IM-9152-3635 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0461; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:F1E8C98C8410BFBA|rigid:Pp4Twp/PfQovOlLiGR28LIHu4c4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83474 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585404|imex:IM-9152-3634 author score:0.441912744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0461; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 intact-crc:68FC3D213D4FC7F9|rigid:/TLJsB5CPvrX8EZ5DxOmFbo87gA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83782 uniprotkb:O83084 intact:EBI-1585420|ensemblbacteria:AAC65771|ensemblbacteria:AGN75976 intact:EBI-1583278|ensemblbacteria:AAC65038 psi-mi:o83782_trepa(display_long)|uniprotkb:TP_0804(locus name) psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585416|imex:IM-9152-3636 author score:0.810026049 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008995(Molybdate/tungstate binding)|interpro:IPR040582|ensemblbacteria:AAC65771(transcript)|ensemblbacteria:AGN75976(transcript)|ensemblbacteria:TP_0804(gene)|ensemblbacteria:TPANIC_0804(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010882249.1|interpro:IPR027417|interpro:IPR015855(ABC transporter, maltose/maltodextrin import, MalK) interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0804; PREY protein TP_0044|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qcgYNmS4aZsHh+bteesc+AGso+Q243276 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 intact-crc:76DBDC26E5C5F7D7|rigid:Lm2+uLZHyk7PFZjCEu3IjcmHs1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83474 uniprotkb:O83847 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 intact:EBI-1198567|intact:EBI-1583350|ensemblbacteria:AAC65840|ensemblbacteria:AGN76046 psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:o83847_trepa(display_long)|uniprotkb:TP_0877(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585425|imex:IM-9152-3637 author score:0.810026049 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR037522|refseq:WP_010882320.1|ensemblbacteria:AAC65840(transcript)|ensemblbacteria:AGN76046(transcript)|ensemblbacteria:TP_0877(gene)|ensemblbacteria:TPANIC_0877(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0877; PREY protein TP_0461|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 rogid:+QpyFXrHDZlRcsvImMZ76wZft48243276 intact-crc:B90391376B122767|rigid:YDjk38+FRB0uNykTnRTwkz7XIhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83442 uniprotkb:O83271 intact:EBI-1585439|ensemblbacteria:AAC65413 intact:EBI-1585431|ensemblbacteria:AAC65232 psi-mi:vatb1_trepa(display_long)|uniprotkb:atpB1(gene name)|psi-mi:atpB1(display_short)|uniprotkb:V-ATPase subunit B 1(gene name synonym)|uniprotkb:TP_0427(locus name) psi-mi:rs12_trepa(display_long)|uniprotkb:rpsL(gene name)|psi-mi:rpsL(display_short)|uniprotkb:TP_0243(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585435|imex:IM-9152-3638 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|ensemblbacteria:AAC65413(transcript)|ensemblbacteria:TP_0427(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|refseq:WP_010881875.1|interpro:IPR027417 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR005679(Ribosomal protein S12, bacterial-type)|ensemblbacteria:AAC65232(transcript)|ensemblbacteria:TP_0243(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881691.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0427; PREY protein TP_0243|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5BBS7hDQ9+xsNVDbKGf+7Vk4enw243276 rogid:Uib53z1GOV+ZWNN89jXVdO5m2Ho243276 intact-crc:AA582EF1EB2C7911|rigid:l1ZPvr10jk32n31O0doGUatcm0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83371 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1585459|ensemblbacteria:AAC65352 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y352_trepa(display_long)|uniprotkb:TP_0352(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585455|imex:IM-9152-3640 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR017154(Uncharacterised conserved protein UCP037246)|ensemblbacteria:AAC65352(transcript)|ensemblbacteria:TP_0352(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:WP_010881800.1|interpro:IPR003173(Transcriptional coactivator p15) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0519; PREY protein TP_0352|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:ehxIiLXzke/y+BDFdC/SXu/qa1U243276 intact-crc:008318328E83B982|rigid:JUgdPX+n4EmBQl15nGSaz1T6s34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83442 uniprotkb:O83348 intact:EBI-1585439|ensemblbacteria:AAC65413 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:vatb1_trepa(display_long)|uniprotkb:atpB1(gene name)|psi-mi:atpB1(display_short)|uniprotkb:V-ATPase subunit B 1(gene name synonym)|uniprotkb:TP_0427(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585445|imex:IM-9152-3639 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|ensemblbacteria:AAC65413(transcript)|ensemblbacteria:TP_0427(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|refseq:WP_010881875.1|interpro:IPR027417 interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0427; PREY protein TP_0328|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5BBS7hDQ9+xsNVDbKGf+7Vk4enw243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:2E590918896E08C6|rigid:43n9t5WH7z4E9mIvQn+Ou/krkWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83503 uniprotkb:O83386 intact:EBI-1585478|ensemblbacteria:AAC65477|ensemblbacteria:AGN75681 intact:EBI-1585474|ensemblbacteria:AAC65356 psi-mi:o83503_trepa(display_long)|uniprotkb:TP_0490(locus name) psi-mi:ispe_trepa(display_long)|uniprotkb:ispE(gene name)|psi-mi:ispE(display_short)|uniprotkb:"4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase"(gene name synonym)|uniprotkb:TP_0371(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585470|imex:IM-9152-3642 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:TPANIC_0490(gene)|ensemblbacteria:AAC65477(transcript)|ensemblbacteria:AGN75681(transcript)|ensemblbacteria:TP_0490(gene)|refseq:WP_010881939.1 interpro:IPR006204(GHMP kinase)|interpro:IPR004424(4-diphosphocytidyl-2C-methyl-D-erythritol kinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65356(transcript)|ensemblbacteria:TP_0371(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0050515"("4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity")|refseq:WP_010881819.1|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0490; PREY protein TP_0371|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nW8Stdly/541maXaO8tn1oEHczU243276 rogid:ES/0eXhZ+H0Qa/tkW2BOa7n+6pQ243276 intact-crc:7DC62CCBEA2ED3DD|rigid:8Lw1jmqDKt+7WHbzaxIzMsrhwOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83532 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585464|imex:IM-9152-3641 author score:0.659399177 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0519; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:4BF61B5894D1CF34|rigid:V9I0gzX8f3QQrwXU9GtyPAE8X20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83890 uniprotkb:O83503 intact:EBI-1583720|ensemblbacteria:AAC65878 intact:EBI-1585478|ensemblbacteria:AAC65477|ensemblbacteria:AGN75681 psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:o83503_trepa(display_long)|uniprotkb:TP_0490(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585483|imex:IM-9152-3643 author score:0.782421663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) ensemblbacteria:TPANIC_0490(gene)|ensemblbacteria:AAC65477(transcript)|ensemblbacteria:AGN75681(transcript)|ensemblbacteria:TP_0490(gene)|refseq:WP_010881939.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0490; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 rogid:nW8Stdly/541maXaO8tn1oEHczU243276 intact-crc:96A1CA37914F824F|rigid:SstV+y9+uB5S70SgpICqz/PtLnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83388 uniprotkb:O83715 intact:EBI-1585492|ensemblbacteria:AAC65358 intact:EBI-1585506|ensemblbacteria:AAC65708 psi-mi:tils_trepa(display_long)|uniprotkb:tilS(gene name)|psi-mi:tilS(display_short)|uniprotkb:"tRNA(Ile)-lysidine synthetase"(gene name synonym)|uniprotkb:"tRNA(Ile)-2-lysyl-cytidine synthase"(gene name synonym)|uniprotkb:TP_0373(locus name) psi-mi:y733_trepa(display_long)|uniprotkb:TP_0733(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585502|imex:IM-9152-3645 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012094(Cell cycle control PP-loop ATPase MesJ/YaeO)|interpro:IPR012796("Lysidine-tRNA(Ile) synthetase, C-terminal")|interpro:IPR012795("Lysidine-tRNA(Ile) synthetase, N-terminal")|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR011063(PP-loop)|go:"GO:0016879"(ligase activity, forming carbon-nitrogen bonds)|ensemblbacteria:AAC65358(transcript)|ensemblbacteria:TP_0373(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|refseq:WP_010881821.1 interpro:IPR011250(Outer membrane protein, beta-barrel)|ensemblbacteria:AAC65708(transcript)|ensemblbacteria:TP_0733(gene)|refseq:WP_010882178.1|interpro:IPR027385 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0373; PREY protein TP_0733|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kLwOwR8BASqF4u6Ehn7CdkaAyE4243276 rogid:JoBcpKMiJuxGO9+5lVaZ/sprnVQ243276 intact-crc:8B7242ADE069237D|rigid:BJXpFxJK+rkQfSk2uxiJV9U7Qpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83388 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1585492|ensemblbacteria:AAC65358 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:tils_trepa(display_long)|uniprotkb:tilS(gene name)|psi-mi:tilS(display_short)|uniprotkb:"tRNA(Ile)-lysidine synthetase"(gene name synonym)|uniprotkb:"tRNA(Ile)-2-lysyl-cytidine synthase"(gene name synonym)|uniprotkb:TP_0373(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585496|imex:IM-9152-3644 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) interpro:IPR012094(Cell cycle control PP-loop ATPase MesJ/YaeO)|interpro:IPR012796("Lysidine-tRNA(Ile) synthetase, C-terminal")|interpro:IPR012795("Lysidine-tRNA(Ile) synthetase, N-terminal")|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR011063(PP-loop)|go:"GO:0016879"(ligase activity, forming carbon-nitrogen bonds)|ensemblbacteria:AAC65358(transcript)|ensemblbacteria:TP_0373(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|refseq:WP_010881821.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0373; PREY protein TP_0409|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:kLwOwR8BASqF4u6Ehn7CdkaAyE4243276 intact-crc:C1A3ABAB8351A557|rigid:CbeUQWEEZuuZa44AaT+QjQv6Ixw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83750 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1585511|ensemblbacteria:AAC65739|ensemblbacteria:AGN75944 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83750_trepa(display_long)|uniprotkb:TP_0771(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585523|imex:IM-9152-3647 author score:0.677298715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR003841(Na+/Pi-cotransporter)|interpro:IPR004633(Na/Pi cotransporter II-related)|interpro:IPR030147|ensemblbacteria:AAC65739(transcript)|ensemblbacteria:AGN75944(transcript)|ensemblbacteria:TP_0771(gene)|ensemblbacteria:TPANIC_0771(gene)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044341"(sodium-dependent phosphate transport)|interpro:IPR038078 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0771; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:hsOxDOX11Gb+UEPi+g0mxPF1C9U243276 intact-crc:FCC82574DA833AC9|rigid:i0ui387i6Wh7oev7ZcUahBwiMj0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83534 uniprotkb:O83750 intact:EBI-1585518|ensemblbacteria:AAC65511 intact:EBI-1585511|ensemblbacteria:AAC65739|ensemblbacteria:AGN75944 psi-mi:y522_trepa(display_long)|uniprotkb:TP_0522(locus name) psi-mi:o83750_trepa(display_long)|uniprotkb:TP_0771(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585514|imex:IM-9152-3646 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003825(Colicin V production protein)|ensemblbacteria:AAC65511(transcript)|ensemblbacteria:TP_0522(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009403"(toxin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881970.1 interpro:IPR003841(Na+/Pi-cotransporter)|interpro:IPR004633(Na/Pi cotransporter II-related)|interpro:IPR030147|ensemblbacteria:AAC65739(transcript)|ensemblbacteria:AGN75944(transcript)|ensemblbacteria:TP_0771(gene)|ensemblbacteria:TPANIC_0771(gene)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044341"(sodium-dependent phosphate transport)|interpro:IPR038078 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0771; PREY protein TP_0522|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CEb2GlcDZ15ZPaSgJ0rJRKKCDjA243276 rogid:hsOxDOX11Gb+UEPi+g0mxPF1C9U243276 intact-crc:6FC2EC0E4439E289|rigid:KmVg4efI1jicn1Ey3Jdf8VYYEsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83619 uniprotkb:O83188 intact:EBI-1585533|ensemblbacteria:AAC65586|ensemblbacteria:AGN75791 intact:EBI-1585536|ensemblbacteria:AAC65143|ensemblbacteria:AGN75372 psi-mi:o83619_trepa(display_long)|uniprotkb:TP_0610(locus name) psi-mi:o83188_trepa(display_long)|uniprotkb:TP_0153(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585529|imex:IM-9152-3648 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|refseq:WP_010882056.1|ensemblbacteria:AAC65586(transcript)|ensemblbacteria:AGN75791(transcript)|ensemblbacteria:TP_0610(gene)|ensemblbacteria:TPANIC_0610(gene) interpro:IPR003832(Acid phosphatase/vanadium-dependent haloperoxidase related)|ensemblbacteria:AAC65143(transcript)|ensemblbacteria:AGN75372(transcript)|ensemblbacteria:TP_0153(gene)|ensemblbacteria:TPANIC_0153(gene)|refseq:WP_010881600.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0153; PREY protein TP_0610|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dqO6wT1ywWuAFOW36caK/OfV0E0243276 rogid:AgpcVFHZpW/xMSSoJ85nOE2jH0c243276 intact-crc:758C4AD32365D535|rigid:3zQYxlsiK++kJSJuBYH53xvl2s8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83188 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1585536|ensemblbacteria:AAC65143|ensemblbacteria:AGN75372 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83188_trepa(display_long)|uniprotkb:TP_0153(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585541|imex:IM-9152-3649 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR003832(Acid phosphatase/vanadium-dependent haloperoxidase related)|ensemblbacteria:AAC65143(transcript)|ensemblbacteria:AGN75372(transcript)|ensemblbacteria:TP_0153(gene)|ensemblbacteria:TPANIC_0153(gene)|refseq:WP_010881600.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0153; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:AgpcVFHZpW/xMSSoJ85nOE2jH0c243276 intact-crc:17248E613B6B0656|rigid:jtvnqYpaD6Q8i2VdEEIBkBN/Wlc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56339 uniprotkb:O54312 intact:EBI-1198657|intact:EBI-1585551|ensemblbacteria:AAC65679 intact:EBI-1585555|ensemblbacteria:AAC65025 psi-mi:flhf_trepa(display_long)|uniprotkb:flhF(gene name)|psi-mi:flhF(display_short)|uniprotkb:TP_0713(locus name)|uniprotkb:Flagella-associated GTP-binding protein(gene name synonym) psi-mi:mura_trepa(display_long)|uniprotkb:murA(gene name)|psi-mi:murA(display_short)|uniprotkb:Enoylpyruvate transferase(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine enolpyruvyl transferase(gene name synonym)|uniprotkb:TP_0029(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585547|imex:IM-9152-3650 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR020006|interpro:IPR027417|refseq:WP_010882158.1|ensemblbacteria:AAC65679(transcript)|ensemblbacteria:TP_0713(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0044781"(bacterial-type flagellum organization) interpro:IPR001986(3-phosphoshikimate 1-carboxyvinyltransferase, core)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR005750(UDP-N-acetylglucosamine 1-carboxyvinyltransferase)|ensemblbacteria:AAC65025(transcript)|ensemblbacteria:TP_0029(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008760"(UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0019277"(UDP-N-acetylgalactosamine biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036968|refseq:WP_010881478.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0029; PREY protein TP_0713|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NqgYRAuKzoUTtoW2Rj35sI57Pbg243276 rogid:d4PyWi87nR8fF05GyNfhlPPwVSs243276 intact-crc:7D860C8E630ECF6F|rigid:jGK1QxGaUgCBzS6jy5gxfytbqzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O54312 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1585555|ensemblbacteria:AAC65025 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:mura_trepa(display_long)|uniprotkb:murA(gene name)|psi-mi:murA(display_short)|uniprotkb:Enoylpyruvate transferase(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine enolpyruvyl transferase(gene name synonym)|uniprotkb:TP_0029(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585561|imex:IM-9152-3651 author score:0.003875236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001986(3-phosphoshikimate 1-carboxyvinyltransferase, core)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR005750(UDP-N-acetylglucosamine 1-carboxyvinyltransferase)|ensemblbacteria:AAC65025(transcript)|ensemblbacteria:TP_0029(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008760"(UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0019277"(UDP-N-acetylgalactosamine biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036968|refseq:WP_010881478.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0029; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:d4PyWi87nR8fF05GyNfhlPPwVSs243276 intact-crc:112FCBABE05CC840|rigid:OhbHMiU8Fvnv0r//bTPHAx1dnHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83763 uniprotkb:O83354 intact:EBI-1585567|ensemblbacteria:AAC65754 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 psi-mi:y784_trepa(display_long)|uniprotkb:TP_0784(locus name) psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585570|imex:IM-9152-3652 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65754(transcript)|ensemblbacteria:TP_0784(gene)|refseq:WP_010882229.1 interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0334; PREY protein TP_0784|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VEzirk2q09KnKgdOSkhFaEjp/eY243276 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 intact-crc:5FEBB216F14752A4|rigid:iehXUPyIGfN8Sf41qIKpPHudPlA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83354 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585579|imex:IM-9152-3653 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0334; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 intact-crc:DE9239D738DCC7AA|rigid:StzTEptlpvpDEXzoI/7LVJ+yX9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83069 uniprotkb:O83898 intact:EBI-1585592|ensemblbacteria:AAC65019|ensemblbacteria:AGN75246 intact:EBI-1585589|ensemblbacteria:AAC65887 psi-mi:o83069_trepa(display_long)|uniprotkb:TP_0025(locus name) psi-mi:y928_trepa(display_long)|uniprotkb:TP_0928(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585585|imex:IM-9152-3654 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR013578(Peptidase M16C associated)|ensemblbacteria:AAC65019(transcript)|ensemblbacteria:AGN75246(transcript)|ensemblbacteria:TP_0025(gene)|ensemblbacteria:TPANIC_0025(gene)|go:"GO:0006508"(proteolysis)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881474.1 ensemblbacteria:AAC65887(transcript)|ensemblbacteria:TP_0928(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882371.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0025; PREY protein TP_0928|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1KmNc1YnAbXluiDkcaTqXLTgNGc243276 rogid:Pk6pOPdwzaF0NT5fTg+KJYTFZLg243276 intact-crc:783DDAC162A2C4C5|rigid:ZZ2igY6aBiCDh8z+RMl5WL0K6M8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O84002 uniprotkb:O83069 intact:EBI-1585598|ensemblbacteria:AAC26594|ensemblbacteria:AGN76204 intact:EBI-1585592|ensemblbacteria:AAC65019|ensemblbacteria:AGN75246 psi-mi:o84002_trepa(display_long)|uniprotkb:TP_1040(locus name) psi-mi:o83069_trepa(display_long)|uniprotkb:TP_0025(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585601|imex:IM-9152-3655 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|ensemblbacteria:AAC26594(transcript)|ensemblbacteria:AGN76204(transcript)|ensemblbacteria:TP_1040(gene)|ensemblbacteria:TPANIC_1040(gene)|go:"GO:0004812"(aminoacyl-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|refseq:WP_010882484.1 interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR013578(Peptidase M16C associated)|ensemblbacteria:AAC65019(transcript)|ensemblbacteria:AGN75246(transcript)|ensemblbacteria:TP_0025(gene)|ensemblbacteria:TPANIC_0025(gene)|go:"GO:0006508"(proteolysis)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881474.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0025; PREY protein TP_1040|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00ZukC7RwwIoMwvK60Mt/eBtcgo243276 rogid:1KmNc1YnAbXluiDkcaTqXLTgNGc243276 intact-crc:22808F433E300D98|rigid:Ext9sMr8Z0aHlILwbJeM3CYl0xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83297 uniprotkb:O83937 intact:EBI-1585614|ensemblbacteria:AAC65275 intact:EBI-1585611|ensemblbacteria:AAC65929|ensemblbacteria:AGN76136 psi-mi:y273_trepa(display_long)|uniprotkb:TP_0273(locus name) psi-mi:o83937_trepa(display_long)|uniprotkb:TP_0972(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585607|imex:IM-9152-3656 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65275(transcript)|ensemblbacteria:TP_0273(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881722.1 interpro:IPR004923(Iron permease FTR1)|ensemblbacteria:AAC65929(transcript)|ensemblbacteria:AGN76136(transcript)|ensemblbacteria:TP_0972(gene)|ensemblbacteria:TPANIC_0972(gene)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|refseq:WP_010882416.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0273; PREY protein TP_0972|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4vooRbQs2rTAew7yS96ACOYh10g243276 rogid:APbFLRjppCsgVZjq044VkEnO440243276 intact-crc:E1DAA801B4186918|rigid:BZq6Pp0PFEfVmZZKzd8iqLzbwTI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83297 uniprotkb:O83887 intact:EBI-1585614|ensemblbacteria:AAC65275 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:y273_trepa(display_long)|uniprotkb:TP_0273(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585619|imex:IM-9152-3657 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65275(transcript)|ensemblbacteria:TP_0273(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881722.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0273; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4vooRbQs2rTAew7yS96ACOYh10g243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:A33A9B59E8D22F9B|rigid:OD1uN5XD6g9fqXGw7BKQ+urgxOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83907 uniprotkb:O83973 intact:EBI-1585633|ensemblbacteria:AAC65894|ensemblbacteria:AGN76102 intact:EBI-1585629|ensemblbacteria:AAC65960 psi-mi:o83907_trepa(display_long)|uniprotkb:TP_0937(locus name) psi-mi:gpda_trepa(display_long)|uniprotkb:gpsA(gene name)|psi-mi:gpsA(display_short)|uniprotkb:"NAD(P)H-dependent glycerol-3-phosphate dehydrogenase"(gene name synonym)|uniprotkb:TP_1009(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585625|imex:IM-9152-3658 author score:0.808666668 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024654|interpro:IPR000979(Protein of unknown function UPF0025)|ensemblbacteria:AAC65894(transcript)|ensemblbacteria:AGN76102(transcript)|ensemblbacteria:TP_0937(gene)|ensemblbacteria:TPANIC_0937(gene)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882380.1|interpro:IPR029052 interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|ensemblbacteria:AAC65960(transcript)|ensemblbacteria:TP_1009(gene)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0046167"(glycerol-3-phosphate biosynthetic process)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0106257"(glycerol-3-phosphate dehydrogenase [NADP+] activity)|refseq:WP_010882453.1|interpro:IPR036291 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0937; PREY protein TP_1009|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3eZsWU72RP9are8twZCoIvzml3g243276 rogid:tS+NO1vvpZKUFTKacQM466Sg9/0243276 intact-crc:48BBC3B3FCAC596C|rigid:SJowH9BWONiCfsJvI369WnHWkWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83890 uniprotkb:O83907 intact:EBI-1583720|ensemblbacteria:AAC65878 intact:EBI-1585633|ensemblbacteria:AAC65894|ensemblbacteria:AGN76102 psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:o83907_trepa(display_long)|uniprotkb:TP_0937(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585638|imex:IM-9152-3659 author score:0.782421663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) interpro:IPR024654|interpro:IPR000979(Protein of unknown function UPF0025)|ensemblbacteria:AAC65894(transcript)|ensemblbacteria:AGN76102(transcript)|ensemblbacteria:TP_0937(gene)|ensemblbacteria:TPANIC_0937(gene)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882380.1|interpro:IPR029052 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0937; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 rogid:3eZsWU72RP9are8twZCoIvzml3g243276 intact-crc:D9CDBE17FDF05187|rigid:PXJMIKn+cEWmx2qUjbCYP0YkovA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83050 uniprotkb:O08399 intact:EBI-1584836|ensemblbacteria:AAC65005 intact:EBI-1585657|ensemblbacteria:AAC65954 psi-mi:y004_trepa(display_long)|uniprotkb:TP_0004(locus name) psi-mi:gyrb_trepa(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:TP_1006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585653|imex:IM-9152-3661 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007922(Protein of unknown function DUF721)|ensemblbacteria:AAC65005(transcript)|ensemblbacteria:TP_0004(gene)|refseq:WP_010881454.1 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|ensemblbacteria:AAC65954(transcript)|go:"GO:0006265"(DNA topological change)|ensemblbacteria:TP_1006(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|refseq:WP_010882450.1|interpro:IPR034160|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1006; PREY protein TP_0004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IxAoquYRvbXKT9V9t6ETfHG8dHo243276 rogid:OkQQ4SjHW9+OzASF/QiIYqo75Lg243276 intact-crc:C9C65F7991AAD40B|rigid:ssC7IHBmTPrt7x6cvmeugxqSalY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83048 uniprotkb:O83838 intact:EBI-1198595|intact:EBI-1583590|ensemblbacteria:AAC65000 intact:EBI-1585644|ensemblbacteria:AAC65844 psi-mi:dpo3b_trepa(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:DNA polymerase III subunit beta(gene name synonym)|uniprotkb:TP_0002(locus name) psi-mi:y867_trepa(display_long)|uniprotkb:TP_0867(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585647|imex:IM-9152-3660 author score:0.805848498 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022635|interpro:IPR022637|interpro:IPR022634|refseq:WP_010881452.1|ensemblbacteria:AAC65000(transcript)|ensemblbacteria:TP_0002(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex) ensemblbacteria:AAC65844(transcript)|ensemblbacteria:TP_0867(gene)|refseq:WP_010882310.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0867; PREY protein TP_0002|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4FZeat7yhkrv79CgJ0/2soG7qD4243276 rogid:CEzzjXaHu84TIMXQyZPZTm4Tdtc243276 intact-crc:2EF7BA7903CB3664|rigid:8Xzr6J56B8zGY5oJ5dpISgKezHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08399 uniprotkb:O83745 intact:EBI-1585657|ensemblbacteria:AAC65954 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:gyrb_trepa(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:TP_1006(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585663|imex:IM-9152-3662 author score:0.135755042 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|ensemblbacteria:AAC65954(transcript)|go:"GO:0006265"(DNA topological change)|ensemblbacteria:TP_1006(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|refseq:WP_010882450.1|interpro:IPR034160|interpro:IPR036890 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1006; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OkQQ4SjHW9+OzASF/QiIYqo75Lg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:1DB1A32592E5473A|rigid:iClD/TOruVXzpG7PCMJe4BxPpik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83409 uniprotkb:O83238 intact:EBI-1585676|ensemblbacteria:AAC65378 intact:EBI-1585669|ensemblbacteria:AAC65198 psi-mi:top1_trepa(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:Omega-protein(gene name synonym)|uniprotkb:Relaxing enzyme(gene name synonym)|uniprotkb:Untwisting enzyme(gene name synonym)|uniprotkb:Swivelase(gene name synonym)|uniprotkb:TP_0394(locus name)|uniprotkb:topA(gene name)|psi-mi:topA(display_short) psi-mi:o83238_trepa(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TP_0208(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585672|imex:IM-9152-3663 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028612|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR023406|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR005733(DNA topoisomerase I, bacterial-type)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65378(transcript)|ensemblbacteria:TP_0394(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005694"(chromosome)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881842.1|interpro:IPR034149|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR000380(DNA topoisomerase, type IA, core) interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|ensemblbacteria:AAC65198(transcript)|ensemblbacteria:TP_0208(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881656.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0394; PREY protein TP_0208|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:b+l9635qNGdcF5WGx386Z5fIeyI243276 rogid:lEmXcpm7ehHfYtWFoAIjCA8/aYA243276 intact-crc:30F85777E7F6B747|rigid:MHL5gHKJg60idkBElzgJJ1o2rzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83744 uniprotkb:O83409 intact:EBI-1585682|ensemblbacteria:AAC65734 intact:EBI-1585676|ensemblbacteria:AAC65378 psi-mi:y763_trepa(display_long)|uniprotkb:TP_0763(locus name) psi-mi:top1_trepa(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:Omega-protein(gene name synonym)|uniprotkb:Relaxing enzyme(gene name synonym)|uniprotkb:Untwisting enzyme(gene name synonym)|uniprotkb:Swivelase(gene name synonym)|uniprotkb:TP_0394(locus name)|uniprotkb:topA(gene name)|psi-mi:topA(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585685|imex:IM-9152-3664 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65734(transcript)|ensemblbacteria:TP_0763(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR028612|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR023406|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR005733(DNA topoisomerase I, bacterial-type)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65378(transcript)|ensemblbacteria:TP_0394(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005694"(chromosome)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881842.1|interpro:IPR034149|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR000380(DNA topoisomerase, type IA, core) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0394; PREY protein TP_0763|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:92wDQngr5kpfX9RmKyfjPh9uS2w243276 rogid:b+l9635qNGdcF5WGx386Z5fIeyI243276 intact-crc:3BED66A09B4037BD|rigid:t2y8o7mYPMrzLglHSkTf/HhDpqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83747 uniprotkb:O83628 intact:EBI-1585691|ensemblbacteria:AAC65741 intact:EBI-1584852|ensemblbacteria:AAC65602 psi-mi:y766_trepa(display_long)|uniprotkb:TP_0766(locus name) psi-mi:y619_trepa(display_long)|uniprotkb:TP_0619(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585694|imex:IM-9152-3665 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65741(transcript)|ensemblbacteria:TP_0766(gene)|refseq:WP_010882211.1 interpro:IPR024471|ensemblbacteria:AAC65602(transcript)|ensemblbacteria:TP_0619(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0766; PREY protein TP_0619|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LvEGDZ20dwblNqdX4rGg/ExYEko243276 rogid:Uu0BCAc+U8Kg1DCfvszCdAprE2o243276 intact-crc:CDFA85731D12EDF0|rigid:3i4XmoLAkNj+CCdsea7lWYU6OxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83747 uniprotkb:O83958 intact:EBI-1585691|ensemblbacteria:AAC65741 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y766_trepa(display_long)|uniprotkb:TP_0766(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585700|imex:IM-9152-3666 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65741(transcript)|ensemblbacteria:TP_0766(gene)|refseq:WP_010882211.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0766; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LvEGDZ20dwblNqdX4rGg/ExYEko243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:4EE582AAB6104E3A|rigid:OWCNF7xbOB9yQMTNdKoR1EaV0eI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83953 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1585706|ensemblbacteria:AAC65944|ensemblbacteria:AGN76152 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83953_trepa(display_long)|uniprotkb:TP_0988(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585718|imex:IM-9152-3668 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR002771("Multiple antibiotic resistance (MarC)-related")|ensemblbacteria:AAC65944(transcript)|ensemblbacteria:AGN76152(transcript)|ensemblbacteria:TP_0988(gene)|ensemblbacteria:TPANIC_0988(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0988; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:yz38vKr3nenayx4DeALgwmme310243276 intact-crc:EC17BD8A0212FB05|rigid:7sNCmIR7QJwnuD0RrKyqNSPJaGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83953 uniprotkb:O83682 intact:EBI-1585706|ensemblbacteria:AAC65944|ensemblbacteria:AGN76152 intact:EBI-1585709|ensemblbacteria:AAC65652 psi-mi:o83953_trepa(display_long)|uniprotkb:TP_0988(locus name) psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585712|imex:IM-9152-3667 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002771("Multiple antibiotic resistance (MarC)-related")|ensemblbacteria:AAC65944(transcript)|ensemblbacteria:AGN76152(transcript)|ensemblbacteria:TP_0988(gene)|ensemblbacteria:TPANIC_0988(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0988; PREY protein TP_0676|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yz38vKr3nenayx4DeALgwmme310243276 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 intact-crc:1ACAB1ADB78904B2|rigid:lUGCsnwg1RABK9wCkFK5YQ4IRBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07886 uniprotkb:O83887 intact:EBI-1198695|intact:EBI-1581566|ensemblbacteria:AAC65690 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:mota_trepa(display_long)|uniprotkb:motA(gene name)|psi-mi:motA(display_short)|uniprotkb:TP_0725(locus name)|uniprotkb:Chemotaxis protein MotA(gene name synonym) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585730|imex:IM-9152-3670 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000540(Flagellar motor protein MotA, conserved site)|interpro:IPR002898(MotA/TolQ/ExbB proton channel)|refseq:WP_010882170.1|ensemblbacteria:AAC65690(transcript)|ensemblbacteria:TP_0725(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0725; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3OvXOYAVlqo9vkKtIsx96P+QdcY243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:3E78A1BD82AA41F2|rigid:En3CHW8vCeKQPYek22fgxGoHzKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07886 uniprotkb:O07886 intact:EBI-1198695|intact:EBI-1581566|ensemblbacteria:AAC65690 intact:EBI-1198695|intact:EBI-1581566|ensemblbacteria:AAC65690 psi-mi:mota_trepa(display_long)|uniprotkb:motA(gene name)|psi-mi:motA(display_short)|uniprotkb:TP_0725(locus name)|uniprotkb:Chemotaxis protein MotA(gene name synonym) psi-mi:mota_trepa(display_long)|uniprotkb:motA(gene name)|psi-mi:motA(display_short)|uniprotkb:TP_0725(locus name)|uniprotkb:Chemotaxis protein MotA(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585724|imex:IM-9152-3669 author score:0.804466441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000540(Flagellar motor protein MotA, conserved site)|interpro:IPR002898(MotA/TolQ/ExbB proton channel)|refseq:WP_010882170.1|ensemblbacteria:AAC65690(transcript)|ensemblbacteria:TP_0725(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility) interpro:IPR000540(Flagellar motor protein MotA, conserved site)|interpro:IPR002898(MotA/TolQ/ExbB proton channel)|refseq:WP_010882170.1|ensemblbacteria:AAC65690(transcript)|ensemblbacteria:TP_0725(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0725; PREY protein TP_0725|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3OvXOYAVlqo9vkKtIsx96P+QdcY243276 rogid:3OvXOYAVlqo9vkKtIsx96P+QdcY243276 intact-crc:116A6257E9B8CB36|rigid:97Rud6WAzOA5maX/PbZ9j75plzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83538 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585736|imex:IM-9152-3671 author score:0.804061976 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:D7E3F56E14BC2769|rigid:OUdDpxkRIlj9tOEEYPwfoz5ljOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83538 uniprotkb:O83222 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 intact:EBI-1583109|ensemblbacteria:AAC65177 psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:rl2_trepa(display_long)|uniprotkb:rplB(gene name)|psi-mi:rplB(display_short)|uniprotkb:TP_0192(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585745|imex:IM-9152-3672 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022666|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR005880(Ribosomal protein L2, bacterial-type)|interpro:IPR022669|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|ensemblbacteria:AAC65177(transcript)|ensemblbacteria:TP_0192(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016740"(transferase activity)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881639.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0192|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 rogid:VUjnMNW+BLMsT1Qxilv1N/DaIV8243276 intact-crc:5DD384A00D020270|rigid:+6Fcp/ll2FPKiK6sdYt/K5XO2og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83538 uniprotkb:O83986 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585760|imex:IM-9152-3674 author score:0.649550157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:0C3DA2C6566FE1CD|rigid:Qr0n7p9UxBr+++Bduv0OwZH7exI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83862 uniprotkb:O83538 intact:EBI-1585751|ensemblbacteria:AAC65849|ensemblbacteria:AGN76061 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:o83862_trepa(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:TP_0892(locus name) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585754|imex:IM-9152-3673 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025249|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010213(Transcription termination factor NusA)|ensemblbacteria:AAC65849(transcript)|ensemblbacteria:AGN76061(transcript)|ensemblbacteria:TP_0892(gene)|ensemblbacteria:TPANIC_0892(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0031564"(transcription antitermination)|interpro:IPR030842|refseq:WP_010882335.1|interpro:IPR036555 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0892|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Es4UvnovxiVAigRDLtBkmPjV03I243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:7B3859987E9C23D1|rigid:97iGERZV3yTWidUjz1dpo3qJ4RU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83538 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585770|imex:IM-9152-3675 author score:0.566373521 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:AFA2BA7D30B92543|rigid:No0lQ1/98W/Nn4OkLY0HQgrOjig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83538 uniprotkb:O83745 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585780|imex:IM-9152-3676 author score:0.082315127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:B2A65A6BF21801C6|rigid:QCTYxm113FysJfEcCr4LAddqFys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83538 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585792|imex:IM-9152-3678 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:7F7F4BA0904A557C|rigid:FQsnirWmQbYmGkngy6GovFRfJFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83538 uniprotkb:O83767 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585786|imex:IM-9152-3677 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:419DC2581A5F3F26|rigid:G2UkFiqPyyJ41Xu2i2OipLpj+jY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83538 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585804|imex:IM-9152-3680 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:559D9476E842A8A4|rigid:cblUwUZ7Z3MTOHB6SusvGb3UPL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83538 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585798|imex:IM-9152-3679 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0526; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 intact-crc:D209EA714208DAF0|rigid:GEdeJdqyr0pGnR98lCih9Wx9DsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:P74928 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585814|imex:IM-9152-3681 author score:0.802353559 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0660|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:7DE149BD4FCB6DFD|rigid:JWIYErhrwS6Lx5i02+faojsIlJ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83261 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585832|imex:IM-9152-3684 author score:0.531037209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:D9485E92CF5F6495|rigid:L6RBF8sEOzHVMqSVAYfI/MmNP7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:P74928 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585826|imex:IM-9152-3683 author score:0.69108919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:E2227537CA5A0C8B|rigid:GwKTmZuEMTXrxGuP/guLPN8rKJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83070 uniprotkb:P74928 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585820|imex:IM-9152-3682 author score:0.792342161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:0C7E6E6FE7779759|rigid:lph80Tz0aOBayzRGq4/X8NPPemo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83761 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198769|intact:EBI-1584687|ensemblbacteria:AAC65752 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y782_trepa(display_long)|uniprotkb:TP_0782(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585838|imex:IM-9152-3685 author score:0.496524451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR011055(Duplicated hybrid motif)|ensemblbacteria:AAC65752(transcript)|ensemblbacteria:TP_0782(gene)|refseq:WP_010882227.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0782|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:hZ2veMAwgO8GWxSx98qAVszLWVI243276 intact-crc:8EF5E84856FC660C|rigid:AeMgZTQPOTPqEgTX5PKYB7j5NVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:P74928 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585850|imex:IM-9152-3687 author score:0.472325769 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0048|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:B350DB78CA37F5F5|rigid:gaa/iFRxyrNnek3/1TelsUf6LPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83138 uniprotkb:P74928 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585844|imex:IM-9152-3686 author score:0.472675303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0100|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:55327E627C985E05|rigid:Z5MHHYWAXRuUF/JWiVkK5q0fqV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83698 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585872|imex:IM-9152-3689 author score:0.407184617 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0700|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 intact-crc:6BE02FFFD11C4879|rigid:w4FdPwDWLyXjOiF1diyKZEuNRQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83223 uniprotkb:P74928 intact:EBI-1198732|intact:EBI-1585859|ensemblbacteria:AAC65178 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:rs19_trepa(display_long)|uniprotkb:rpsS(gene name)|psi-mi:rpsS(display_short)|uniprotkb:TP_0193(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585863|imex:IM-9152-3688 author score:0.407184617 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005732(Ribosomal protein S19, bacterial-type)|interpro:IPR020934|interpro:IPR023575|refseq:WP_010881640.1|ensemblbacteria:AAC65178(transcript)|ensemblbacteria:TP_0193(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0193|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:EBhFBJ6rA8hNYYWEGpwdquYzXqQ243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:A3ADC3BB8ECF6EFA|rigid:sSkb5veMgbzl4RZCFXloXxlUKEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83815 uniprotkb:P74928 intact:EBI-1198773|intact:EBI-1583380|ensemblbacteria:AAC65811|ensemblbacteria:AGN76013 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83815_trepa(display_long)|uniprotkb:TP_0843(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585884|imex:IM-9152-3691 author score:0.394254978 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|refseq:WP_010882287.1|ensemblbacteria:AAC65811(transcript)|ensemblbacteria:AGN76013(transcript)|ensemblbacteria:TP_0843(gene)|ensemblbacteria:TPANIC_0843(gene)|interpro:IPR036869 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0843|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:h3WpgPV9/A/O8FQT3fN+2+aJjDo243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:DE62CB2478E231EC|rigid:AzjAQRh6QOqDcs3Y3gMClqEZWWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:P74928 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585878|imex:IM-9152-3690 author score:0.394254978 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0772|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:702753BF3E8F13A7|rigid:Yg5/T+fkwpekwhfJpQKlWtqtOBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83588 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585896|imex:IM-9152-3693 author score:0.381471709 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0579|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 intact-crc:07381672F6AA53C9|rigid:wZX02X3Lq30gbjysrtxkQtRfrsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83195 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585890|imex:IM-9152-3692 author score:0.393534882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:5546DF466E7B1B45|rigid:UWfjoK+zKxc85XzrESn7MOKOQbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83126 uniprotkb:P74928 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585908|imex:IM-9152-2674 author score:0.362605416 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:A317CBC6330255BE|rigid:K3WSegHbqFxSjKHtQ4YBAtEDMZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83637 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585902|imex:IM-9152-2673 author score:0.37513991 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 intact-crc:FC379560BB765AE9|rigid:B+GXhY6LOHR/ZP8wikFCRtGCBFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83105 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585920|imex:IM-9152-2676 author score:0.344153024 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:9F67C6A743E0ED3C|rigid:CvcsxaqQuq5TFBsx7hw/39YyAaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:P74928 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585914|imex:IM-9152-2675 author score:0.34891057 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:E19D42071B92FE0E|rigid:ILX6XW+Ncb9VmoVH/3ZgVa8f2G8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83239 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585932|imex:IM-9152-2678 author score:0.254339443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:B8FAA48008CC63AC|rigid:MqrhPBN3pUd5CVIaRL4TkKsiQ9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:P74928 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585926|imex:IM-9152-2677 author score:0.310764986 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:AF5B34BFE97A6091|rigid:R8/0gWC0GRwcAxGBnyPHjpLGEZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:P74928 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585938|imex:IM-9152-2679 author score:0.254339443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:78D74FD9902BEF2B|rigid:c4jPxEBHXhaVQj/iN4qMCQsM/Ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:P74928 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585956|imex:IM-9152-2682 author score:0.206717631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:4E2A953B5FC92A7B|rigid:BHLPL11RXTDultd8oZQhaUZq8v8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83970 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585950|imex:IM-9152-2681 author score:0.216918125 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:514B95ECDD8A740B|rigid:tvLCAL0WwKJfYg6E8kHPYbm6eeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83805 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585944|imex:IM-9152-2680 author score:0.220276113 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:39F2007D3F587492|rigid:mxs+1e6lCe+gaOB53xoGA89VLBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83312 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585962|imex:IM-9152-2683 author score:0.081531024 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:B9818F891A4E1FCD|rigid:WzJzTuIELthJJB7BgogIatliw+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:P74928 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585968|imex:IM-9152-2684 author score:0.054553051 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 intact-crc:D66D640A4D27AEAB|rigid:jsnUnnv2Sksls55nynt6mCvEbOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83877 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585974|imex:IM-9152-2685 author score:0.03522407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:9A741BD0AF6201CB|rigid:Zs8wko0IEi2t4WOD4BtXa6FsNF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83767 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585986|imex:IM-9152-2687 author score:0.01979251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:8B500E59679E2B0C|rigid:0/7Xn0mOodM0goz7KHBJHhh5egI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83745 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585980|imex:IM-9152-2686 author score:0.028818696 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:381CDA3BB3AD4F57|rigid:F7UJFQT6PhXl3bGLMDW07IA+eGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83954 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585998|imex:IM-9152-2689 author score:0.005515076 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:BB0BB6CC0C9FB1F8|rigid:+T2UqHc4ovA5ZfX1LoaQOfU9+cI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83282 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1585992|imex:IM-9152-2688 author score:0.006651216 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:FAFF31CF869B772A|rigid:Sdxn+o3sPiH3rRqVQUM0exOcywo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83704 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1586014|ensemblbacteria:AAC65674|ensemblbacteria:AGN75881 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83704_trepa(display_long)|uniprotkb:TP_0706(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586010|imex:IM-9152-2691 author score:0.801309632 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|refseq:WP_010882151.1|ensemblbacteria:AAC65674(transcript)|ensemblbacteria:AGN75881(transcript)|ensemblbacteria:TP_0706(gene)|ensemblbacteria:TPANIC_0706(gene)|interpro:IPR036779 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0706; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:bCEw6vbisllpqN0UcOVSpKh7a9o243276 intact-crc:D4435C069E077885|rigid:U3Aq0dUn5g+sgAYiXw2ARYtnlrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74928 uniprotkb:O83958 intact:EBI-1198716|intact:EBI-1585810|uniprotkb:Q7DFN9 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:p74928_trepl(display_long)|uniprotkb:fliY(gene name)|psi-mi:fliY(display_short)|uniprotkb:FA889_03730(orf name)|uniprotkb:fliN(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586004|imex:IM-9152-2690 author score:0.000328187 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012826(Flagellar motor switch FliN)|interpro:IPR001172(Flagellar motor switch FliN/Type III secretion HrcQb)|interpro:IPR001543("Surface presentation of antigens (SPOA) protein")|interpro:IPR028976|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|interpro:IPR036429|refseq:WP_010882165.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0720; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o/AuFINrNq1PbZHDEpZYWxDIjfg160 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:E32B00291CBFB5F7|rigid:0+NQPUB+lfYwTrvTq2u27+vVjYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83704 uniprotkb:O83745 intact:EBI-1586014|ensemblbacteria:AAC65674|ensemblbacteria:AGN75881 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83704_trepa(display_long)|uniprotkb:TP_0706(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586025|imex:IM-9152-2693 author score:0.162845161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|refseq:WP_010882151.1|ensemblbacteria:AAC65674(transcript)|ensemblbacteria:AGN75881(transcript)|ensemblbacteria:TP_0706(gene)|ensemblbacteria:TPANIC_0706(gene)|interpro:IPR036779 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0706; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bCEw6vbisllpqN0UcOVSpKh7a9o243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:D40EE5679D312233|rigid:OZGCZMmxCc1yP1XYO3Ub+BHy40g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83704 uniprotkb:O83670 intact:EBI-1586014|ensemblbacteria:AAC65674|ensemblbacteria:AGN75881 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83704_trepa(display_long)|uniprotkb:TP_0706(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586019|imex:IM-9152-2692 author score:0.605304872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|refseq:WP_010882151.1|ensemblbacteria:AAC65674(transcript)|ensemblbacteria:AGN75881(transcript)|ensemblbacteria:TP_0706(gene)|ensemblbacteria:TPANIC_0706(gene)|interpro:IPR036779 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0706; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bCEw6vbisllpqN0UcOVSpKh7a9o243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:F2152AFEFC609852|rigid:SaZXpeq8q1voxAdWp+ah9NykjYI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:Q08255 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586037|imex:IM-9152-2695 author score:0.800391753 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0757; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:965D8F7F081E91E6|rigid:SkU/gz7etuMiQBshh6OHI/LLCSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83704 uniprotkb:O83954 intact:EBI-1586014|ensemblbacteria:AAC65674|ensemblbacteria:AGN75881 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83704_trepa(display_long)|uniprotkb:TP_0706(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586031|imex:IM-9152-2694 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|refseq:WP_010882151.1|ensemblbacteria:AAC65674(transcript)|ensemblbacteria:AGN75881(transcript)|ensemblbacteria:TP_0706(gene)|ensemblbacteria:TPANIC_0706(gene)|interpro:IPR036779 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0706; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bCEw6vbisllpqN0UcOVSpKh7a9o243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:463637A8F18DA162|rigid:WbYynV+RHxFgpAfQFr21AWKAtnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83805 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586043|imex:IM-9152-2696 author score:0.605304872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0757; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:03B6AE2E18342EE5|rigid:dc78RMznZSiwozBpwkS8Hz0soQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83958 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586055|imex:IM-9152-2698 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0757; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:F0A65451692B29E5|rigid:9TKlhkhUdj4oEDDUtfkH9P8zPFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83767 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586049|imex:IM-9152-2697 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0757; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:A1AD2CF2E9B4AF4D|rigid:eM//VHHvZyNRi3mVO5jQak2yJ/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1586061 uniprotkb:Q56344 - intact:EBI-1586062|uniprotkb:Q7DFQ1 psi-mi:tp_0290(display_short)|psi-mi:EBI-1586061(display_long) psi-mi:q56344_trepl(display_long)|uniprotkb:mcp-1(gene name)|psi-mi:mcp-1(display_short)|uniprotkb:FA889_00210(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586066|imex:IM-9152-2699 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881489.1 psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0290; PREY protein TP_0040|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:d41nLojm5ajwUm9NNC1lPiTcqi0160 intact-crc:F31321F004F9716A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83084 intact:EBI-1586061 intact:EBI-1583278|ensemblbacteria:AAC65038 - psi-mi:mnmg_trepa(display_long)|uniprotkb:mnmG(gene name)|psi-mi:mnmG(display_short)|uniprotkb:gidA(gene name synonym)|uniprotkb:Glucose-inhibited division protein A(gene name synonym)|uniprotkb:TP_0044(locus name) psi-mi:tp_0290(display_short)|psi-mi:EBI-1586061(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586072|imex:IM-9152-2700 author score:0.789990817 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR026904|ensemblbacteria:AAC65038(transcript)|ensemblbacteria:TP_0044(gene)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005737"(cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR020595|refseq:WP_010881493.1|interpro:IPR040131|interpro:IPR036188|interpro:IPR044920 - psi-mi:"MI:0469"(intact) - no-uniprot-update: author-identifiers:BAIT protein TP_0290; PREY protein TP_0044|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YnNX3+RNhgsPTCSxFHEyqGcFwmY243276 - intact-crc:BBDADAD0161C41B8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1586061 uniprotkb:O83745 - intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:tp_0290(display_short)|psi-mi:EBI-1586061(display_long) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586078|imex:IM-9152-2701 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0290; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:227898CDB6C6E6B2 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83320 uniprotkb:O83116 intact:EBI-1586091|ensemblbacteria:AAC65286|ensemblbacteria:AGN75502 intact:EBI-1586088|ensemblbacteria:AAC65072|ensemblbacteria:AGN75296 psi-mi:o83320_trepa(display_long)|uniprotkb:TP_0297(locus name) psi-mi:o83116_trepa(display_long)|uniprotkb:TP_0077(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586084|imex:IM-9152-2702 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65286(transcript)|ensemblbacteria:AGN75502(transcript)|ensemblbacteria:TP_0297(gene)|ensemblbacteria:TPANIC_0297(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010881746.1|interpro:IPR036680 interpro:IPR003869(Polysaccharide biosynthesis protein CapD)|ensemblbacteria:AAC65072(transcript)|ensemblbacteria:AGN75296(transcript)|ensemblbacteria:TP_0077(gene)|ensemblbacteria:TPANIC_0077(gene)|refseq:WP_010881526.1|interpro:IPR036291 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0297; PREY protein TP_0077|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9V/y5YX+FS4/TGDIpgtwK1Tp0tc243276 rogid:O3zntxZ5EpPqtPsSVRaDA4jn/4o243276 intact-crc:3DA7F8A7FB86D9B8|rigid:AycXeHfbA4DfHTlPegJDeB+KwyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83320 uniprotkb:O83720 intact:EBI-1586091|ensemblbacteria:AAC65286|ensemblbacteria:AGN75502 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83320_trepa(display_long)|uniprotkb:TP_0297(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586096|imex:IM-9152-2703 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65286(transcript)|ensemblbacteria:AGN75502(transcript)|ensemblbacteria:TP_0297(gene)|ensemblbacteria:TPANIC_0297(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010881746.1|interpro:IPR036680 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0297; PREY protein TP_0738|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9V/y5YX+FS4/TGDIpgtwK1Tp0tc243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:3695EEECC7EABDE1|rigid:ZnFZkI5WnvB2+eaCqyc7gfkyF0A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83149 uniprotkb:O83612 intact:EBI-1586119|ensemblbacteria:AAC65101 intact:EBI-1586111|ensemblbacteria:AAC65576 psi-mi:rp54_trepa(display_long)|uniprotkb:rpoN(gene name)|psi-mi:rpoN(display_short)|uniprotkb:TP_0111(locus name) psi-mi:ispt_trepa(display_long)|uniprotkb:uppS(gene name)|psi-mi:uppS(display_short)|uniprotkb:TP_0603(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586115|imex:IM-9152-2705 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|ensemblbacteria:AAC65101(transcript)|ensemblbacteria:TP_0111(gene)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity) interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblbacteria:AAC65576(transcript)|ensemblbacteria:TP_0603(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004659"(prenyltransferase activity)|refseq:WP_010882049.1|interpro:IPR036424 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0603; PREY protein TP_0111|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Swze8dOUOAa3pYgYd2J4MX+Rf2w243276 rogid:C+WBymKUNmSDvexJQrv2NWCxD0I243276 intact-crc:43CBB5CF4D4EE8E8|rigid:mXuF8pargxm+MjHz/uOvSJdIODI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83264 uniprotkb:O83320 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 intact:EBI-1586091|ensemblbacteria:AAC65286|ensemblbacteria:AGN75502 psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:o83320_trepa(display_long)|uniprotkb:TP_0297(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586105|imex:IM-9152-2704 author score:0.780918179 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65286(transcript)|ensemblbacteria:AGN75502(transcript)|ensemblbacteria:TP_0297(gene)|ensemblbacteria:TPANIC_0297(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010881746.1|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0297; PREY protein TP_0236|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 rogid:9V/y5YX+FS4/TGDIpgtwK1Tp0tc243276 intact-crc:E5BE16CE0C4E74A1|rigid:uBXpFjz8ZqLM2Ad3cUnQchJ/wBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83612 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1586111|ensemblbacteria:AAC65576 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:ispt_trepa(display_long)|uniprotkb:uppS(gene name)|psi-mi:uppS(display_short)|uniprotkb:TP_0603(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586125|imex:IM-9152-2706 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblbacteria:AAC65576(transcript)|ensemblbacteria:TP_0603(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004659"(prenyltransferase activity)|refseq:WP_010882049.1|interpro:IPR036424 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0603; PREY protein TP_0284|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:C+WBymKUNmSDvexJQrv2NWCxD0I243276 intact-crc:ACE2B44C23241DEC|rigid:LjDT+DW7G38HTTJcwdNdNM1uWa8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83612 uniprotkb:O83439 intact:EBI-1586111|ensemblbacteria:AAC65576 intact:EBI-1586134|ensemblbacteria:AAC65411 psi-mi:ispt_trepa(display_long)|uniprotkb:uppS(gene name)|psi-mi:uppS(display_short)|uniprotkb:TP_0603(locus name) psi-mi:vate_trepa(display_long)|uniprotkb:atpE(gene name)|psi-mi:atpE(display_short)|uniprotkb:V-ATPase subunit E(gene name synonym)|uniprotkb:TP_0424(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586138|imex:IM-9152-2707 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|ensemblbacteria:AAC65576(transcript)|ensemblbacteria:TP_0603(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004659"(prenyltransferase activity)|refseq:WP_010882049.1|interpro:IPR036424 ensemblbacteria:AAC65411(transcript)|ensemblbacteria:TP_0424(gene)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0603; PREY protein TP_0424|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:C+WBymKUNmSDvexJQrv2NWCxD0I243276 rogid:thNeo9prIZeKnVV0CklqTbWHGZQ243276 intact-crc:E8A7056DF622EA3D|rigid:KACFCnFJTPO/S+/i4jR6cfYERrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83215 uniprotkb:O83466 intact:EBI-1586144|ensemblbacteria:AAC65170|ensemblbacteria:AGN75399 intact:EBI-1586151|ensemblbacteria:AAC65439 psi-mi:o83215_trepa(display_long)|uniprotkb:TP_0185(locus name) psi-mi:syi_trepa(display_long)|uniprotkb:ileS(gene name)|psi-mi:ileS(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0452(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586147|imex:IM-9152-2708 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000223(Peptidase S26A, signal peptidase I)|ensemblbacteria:AAC65170(transcript)|ensemblbacteria:AGN75399(transcript)|ensemblbacteria:TP_0185(gene)|ensemblbacteria:TPANIC_0185(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881632.1|interpro:IPR036286|interpro:IPR019533 interpro:IPR033709|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023586|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|ensemblbacteria:AAC65439(transcript)|ensemblbacteria:TP_0452(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010881901.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0452; PREY protein TP_0185|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OpqygOQJ4r+cTeqT0R3CKdk8sVk243276 rogid:lRHSw79eOGJnZBHCQrWWdbprpwg243276 intact-crc:FF5BF736B65B6FEB|rigid:WM2g/UxJiNyvr9psh70kOLmJC/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83466 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1586151|ensemblbacteria:AAC65439 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:syi_trepa(display_long)|uniprotkb:ileS(gene name)|psi-mi:ileS(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0452(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586164|imex:IM-9152-2710 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR033709|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023586|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|ensemblbacteria:AAC65439(transcript)|ensemblbacteria:TP_0452(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010881901.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0452; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:lRHSw79eOGJnZBHCQrWWdbprpwg243276 intact-crc:CC220D2CCAE26C36|rigid:yPZ42yIzOalxPmn9w/6k2fXDAZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83466 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1586151|ensemblbacteria:AAC65439 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:syi_trepa(display_long)|uniprotkb:ileS(gene name)|psi-mi:ileS(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0452(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586158|imex:IM-9152-2709 author score:0.720703806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR033709|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR023586|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|ensemblbacteria:AAC65439(transcript)|ensemblbacteria:TP_0452(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010881901.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0452; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:lRHSw79eOGJnZBHCQrWWdbprpwg243276 intact-crc:09AE22475AA76895|rigid:lDc6SktGbKf5qvO25s4tRpIorAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83663 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1583860|ensemblbacteria:AAC65631 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:csra_trepa(display_long)|uniprotkb:csrA(gene name)|psi-mi:csrA(display_short)|uniprotkb:TP_0657(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586179|imex:IM-9152-2712 author score:0.382503445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65631(transcript)|ensemblbacteria:TP_0657(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|interpro:IPR003751(Carbon storage regulator)|go:"GO:1902208"(regulation of bacterial-type flagellum assembly)|refseq:WP_010882102.1|interpro:IPR036107 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0657; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:xgEY9t+7VT0qj3fvWe/VSG+P/MA243276 intact-crc:56FADBBC36506DD8|rigid:/7YaRro5M7QLc2C0GavKJMq0yOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83663 uniprotkb:O83254 intact:EBI-1583860|ensemblbacteria:AAC65631 intact:EBI-1586174|ensemblbacteria:AAC65219 psi-mi:csra_trepa(display_long)|uniprotkb:csrA(gene name)|psi-mi:csrA(display_short)|uniprotkb:TP_0657(locus name) psi-mi:y226_trepa(display_long)|uniprotkb:TP_0226(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586170|imex:IM-9152-2711 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65631(transcript)|ensemblbacteria:TP_0657(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|interpro:IPR003751(Carbon storage regulator)|go:"GO:1902208"(regulation of bacterial-type flagellum assembly)|refseq:WP_010882102.1|interpro:IPR036107 interpro:IPR003339(Cobalt transport protein)|ensemblbacteria:AAC65219(transcript)|ensemblbacteria:TP_0226(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881674.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0657; PREY protein TP_0226|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xgEY9t+7VT0qj3fvWe/VSG+P/MA243276 rogid:h5Hg/rrUj4sqzinkZFs/Dc5CkBY243276 intact-crc:DAF0FB8CE771D2E9|rigid:cX9c5EYZYxFXg7pVz7iNBQexb68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96118 uniprotkb:P18193 intact:EBI-1586199|ensemblbacteria:AAC65155 intact:EBI-1586191|ensemblbacteria:AAC65235 psi-mi:troc_trepa(display_long)|uniprotkb:troC(gene name)|psi-mi:troC(display_short)|uniprotkb:TP_0165(locus name) psi-mi:flaa_trepa(display_long)|uniprotkb:flaA(gene name)|psi-mi:flaA(display_short)|uniprotkb:Sheath protein(gene name synonym)|uniprotkb:TP_0249(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586195|imex:IM-9152-2714 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001626(ABC-3)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|ensemblbacteria:AAC65155(transcript)|ensemblbacteria:TP_0165(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006829"(zinc ion transport)|refseq:WP_010881612.1|interpro:IPR037294 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|interpro:IPR016369(Flagellar filament outer layer protein FlaA, subgroup)|ensemblbacteria:AAC65235(transcript)|ensemblbacteria:TP_0249(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881697.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0165; PREY protein TP_0249|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Eh3Ld/EDQxnMxGxzx8hC7c2CMqg243276 rogid:FbjGeQiNHKq7slk2Ee+ufrwqhVg243276 intact-crc:499E699E41B46E14|rigid:bbnTYkU1U0qiGq0i7px0Sbpiw0w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83663 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1583860|ensemblbacteria:AAC65631 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:csra_trepa(display_long)|uniprotkb:csrA(gene name)|psi-mi:csrA(display_short)|uniprotkb:TP_0657(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586185|imex:IM-9152-2713 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65631(transcript)|ensemblbacteria:TP_0657(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0044781"(bacterial-type flagellum organization)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|interpro:IPR003751(Carbon storage regulator)|go:"GO:1902208"(regulation of bacterial-type flagellum assembly)|refseq:WP_010882102.1|interpro:IPR036107 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0657; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:xgEY9t+7VT0qj3fvWe/VSG+P/MA243276 intact-crc:ED057B017566EEDC|rigid:sc0eZkIyP6Pwiz6kCiKWZhiw2DU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96118 uniprotkb:O83850 intact:EBI-1586199|ensemblbacteria:AAC65155 intact:EBI-1586209|ensemblbacteria:AAC65842|ensemblbacteria:AGN76049 psi-mi:troc_trepa(display_long)|uniprotkb:troC(gene name)|psi-mi:troC(display_short)|uniprotkb:TP_0165(locus name) psi-mi:o83850_trepa(display_long)|uniprotkb:TP_0880(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586205|imex:IM-9152-2715 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001626(ABC-3)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|ensemblbacteria:AAC65155(transcript)|ensemblbacteria:TP_0165(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006829"(zinc ion transport)|refseq:WP_010881612.1|interpro:IPR037294 ensemblbacteria:AAC65842(transcript)|ensemblbacteria:AGN76049(transcript)|ensemblbacteria:TP_0880(gene)|ensemblbacteria:TPANIC_0880(gene)|refseq:WP_010882323.1|interpro:IPR025699 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0165; PREY protein TP_0880|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Eh3Ld/EDQxnMxGxzx8hC7c2CMqg243276 rogid:YnCITab2vyISVmGkTw61JqUnMfk243276 intact-crc:D1531B5DA3F09C8A|rigid:4rxIi/HmCjIh1YXwLmfBfysAzCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96118 uniprotkb:O83887 intact:EBI-1586199|ensemblbacteria:AAC65155 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:troc_trepa(display_long)|uniprotkb:troC(gene name)|psi-mi:troC(display_short)|uniprotkb:TP_0165(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586214|imex:IM-9152-2716 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001626(ABC-3)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|ensemblbacteria:AAC65155(transcript)|ensemblbacteria:TP_0165(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006829"(zinc ion transport)|refseq:WP_010881612.1|interpro:IPR037294 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0165; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Eh3Ld/EDQxnMxGxzx8hC7c2CMqg243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:BFF1F7B1D58E2291|rigid:hHeToj8ctNEzW1fc0vaY8piXAFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16665 uniprotkb:O83773 intact:EBI-1586220|ensemblbacteria:AAC26592 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:tpf1_trepa(display_long)|uniprotkb:tpf1(gene name)|psi-mi:tpf1(display_short)|uniprotkb:Antigen C1-5(gene name synonym)|uniprotkb:Antigen 4D(gene name synonym)|uniprotkb:TP_1038(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586233|imex:IM-9152-2718 author score:0.785489362 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002177(DNA-binding protein Dps)|interpro:IPR023188|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:2FJC|ensemblbacteria:AAC26592(transcript)|ensemblbacteria:TP_1038(gene)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016722"(oxidoreductase activity, acting on metal ions)|refseq:WP_010882482.1 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1038; PREY protein TP_0795|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BK37nf7xvFpihDWKEQkShrBNzGU243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:FAF95C53DC00A646|rigid:lSX1VN8kxNLTtU8TWKo0/Z+ocDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16665 uniprotkb:O83324 intact:EBI-1586220|ensemblbacteria:AAC26592 intact:EBI-1586228|ensemblbacteria:AAC65290|ensemblbacteria:AGN75506 psi-mi:tpf1_trepa(display_long)|uniprotkb:tpf1(gene name)|psi-mi:tpf1(display_short)|uniprotkb:Antigen C1-5(gene name synonym)|uniprotkb:Antigen 4D(gene name synonym)|uniprotkb:TP_1038(locus name) psi-mi:rfud_trepa(display_long)|uniprotkb:rfuD(gene name)|psi-mi:rfuD(display_short)|uniprotkb:TPANIC_0302(orf name)|uniprotkb:TP_0302(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586224|imex:IM-9152-2717 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002177(DNA-binding protein Dps)|interpro:IPR023188|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:2FJC|ensemblbacteria:AAC26592(transcript)|ensemblbacteria:TP_1038(gene)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016722"(oxidoreductase activity, acting on metal ions)|refseq:WP_010882482.1 interpro:IPR001851(Bacterial inner-membrane translocator)|ensemblbacteria:AAC65290(transcript)|ensemblbacteria:AGN75506(transcript)|ensemblbacteria:TP_0302(gene)|ensemblbacteria:TPANIC_0302(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010881751.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1038; PREY protein TP_0302|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BK37nf7xvFpihDWKEQkShrBNzGU243276 rogid:FIaKRVgLj4PQ9+o2zpdqvaCRogM243276 intact-crc:91217E6E5A15E141|rigid:SVR07+PULicU8/Pf5zYX/QvlcLQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:P16665 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1586220|ensemblbacteria:AAC26592 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:tpf1_trepa(display_long)|uniprotkb:tpf1(gene name)|psi-mi:tpf1(display_short)|uniprotkb:Antigen C1-5(gene name synonym)|uniprotkb:Antigen 4D(gene name synonym)|uniprotkb:TP_1038(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586239|imex:IM-9152-2719 author score:0.720703806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR002177(DNA-binding protein Dps)|interpro:IPR023188|interpro:IPR012347(Ferritin-related)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR008331(Ferritin and Dps)|rcsb pdb:2FJC|ensemblbacteria:AAC26592(transcript)|ensemblbacteria:TP_1038(gene)|go:"GO:0008199"(ferric iron binding)|go:"GO:0016722"(oxidoreductase activity, acting on metal ions)|refseq:WP_010882482.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1038; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:BK37nf7xvFpihDWKEQkShrBNzGU243276 intact-crc:14E13F5EC65C056B|rigid:ELz9/xsjkpJ6+NhOfTzxEalZEWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83585 uniprotkb:O83598 intact:EBI-1586253|ensemblbacteria:AAC65552 intact:EBI-1586249|ensemblbacteria:AAC65564 psi-mi:rf2_trepa(display_long)|uniprotkb:prfB(gene name)|psi-mi:prfB(display_short)|uniprotkb:TP_0576(locus name) psi-mi:pthp_trepa(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:Histidine-containing protein(gene name synonym)|uniprotkb:TP_0589(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586245|imex:IM-9152-2720 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005139(PCRF)|interpro:IPR000352(Class I peptide chain release factor)|interpro:IPR004374(Peptide chain release factor 2)|refseq:WP_010882022.1|ensemblbacteria:AAC65552(transcript)|ensemblbacteria:TP_0576(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0016149"(translation release factor activity, codon specific) interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|ensemblbacteria:TP_0589(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|ensemblbacteria:AAC65564(transcript)|refseq:WP_010882035.1|interpro:IPR035895 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0589; PREY protein TP_0576|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tSzS15hyg/w6e7VW7QkG1XP9vPY243276 rogid:qTeek+XL/a+ZFhq9XV8MFSXkLxM243276 intact-crc:49CA2D687036F326|rigid:05d95nRvYxM3R7BUqegFDD+qbTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83598 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586249|ensemblbacteria:AAC65564 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:pthp_trepa(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:Histidine-containing protein(gene name synonym)|uniprotkb:TP_0589(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586265|imex:IM-9152-2722 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|ensemblbacteria:TP_0589(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|ensemblbacteria:AAC65564(transcript)|refseq:WP_010882035.1|interpro:IPR035895 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0589; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:qTeek+XL/a+ZFhq9XV8MFSXkLxM243276 intact-crc:20EC2B499E73EAE1|rigid:rjCLQ0OxUPDEVY3jqdpVxYGhz+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83598 uniprotkb:O83413 intact:EBI-1586249|ensemblbacteria:AAC65564 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:pthp_trepa(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:Histidine-containing protein(gene name synonym)|uniprotkb:TP_0589(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586259|imex:IM-9152-2721 author score:0.196210542 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|ensemblbacteria:TP_0589(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|ensemblbacteria:AAC65564(transcript)|refseq:WP_010882035.1|interpro:IPR035895 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0589; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qTeek+XL/a+ZFhq9XV8MFSXkLxM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:AAB4E32FA6E40CC4|rigid:SDFuHmR2xslB2l1agD0qsXp6a2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83601 uniprotkb:O83463 intact:EBI-1586278|ensemblbacteria:AAC65570|ensemblbacteria:AGN75775 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83601_trepa(display_long)|uniprotkb:TP_0592(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586283|imex:IM-9152-2724 author score:0.508147082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65570(transcript)|ensemblbacteria:AGN75775(transcript)|ensemblbacteria:TP_0592(gene)|ensemblbacteria:TPANIC_0592(gene)|go:"GO:0008233"(peptidase activity)|refseq:WP_010882038.1|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR039561 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0592; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7zTzu+LqmzOrhqxuY6KcodOXBoo243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:30724846374321E0|rigid:K60Ni908HlvYyjimkui0EYnjW6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83601 uniprotkb:O83592 intact:EBI-1586278|ensemblbacteria:AAC65570|ensemblbacteria:AGN75775 intact:EBI-1586275|ensemblbacteria:AAC65561 psi-mi:o83601_trepa(display_long)|uniprotkb:TP_0592(locus name) psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586271|imex:IM-9152-2723 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65570(transcript)|ensemblbacteria:AGN75775(transcript)|ensemblbacteria:TP_0592(gene)|ensemblbacteria:TPANIC_0592(gene)|go:"GO:0008233"(peptidase activity)|refseq:WP_010882038.1|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR039561 ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0592; PREY protein TP_0583|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7zTzu+LqmzOrhqxuY6KcodOXBoo243276 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 intact-crc:7F32786EADBDA7DF|rigid:98yJniillG1aAFmEDfAxe6dYaNo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83661 uniprotkb:O83568 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 intact:EBI-1586298|ensemblbacteria:AAC26561|ensemblbacteria:AGN75744 psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:o83568_trepa(display_long)|uniprotkb:TP_0557(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586301|imex:IM-9152-2726 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 interpro:IPR010412(Protein of unknown function DUF1007)|interpro:IPR016537(Uncharacterised conserved protein UCP008159,)|ensemblbacteria:AAC26561(transcript)|ensemblbacteria:AGN75744(transcript)|ensemblbacteria:TP_0557(gene)|ensemblbacteria:TPANIC_0557(gene)|refseq:WP_010882004.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0557; PREY protein TP_0655|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 rogid:FdELVF3vi0YE5cLgAUA1Ro7i4YE243276 intact-crc:2A4DBE2D45997E85|rigid:Z8ApRi8+ZR91/u3zkjjhpXlcMyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83601 uniprotkb:O83282 intact:EBI-1586278|ensemblbacteria:AAC65570|ensemblbacteria:AGN75775 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83601_trepa(display_long)|uniprotkb:TP_0592(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586289|imex:IM-9152-2725 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65570(transcript)|ensemblbacteria:AGN75775(transcript)|ensemblbacteria:TP_0592(gene)|ensemblbacteria:TPANIC_0592(gene)|go:"GO:0008233"(peptidase activity)|refseq:WP_010882038.1|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)|interpro:IPR039561 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0592; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7zTzu+LqmzOrhqxuY6KcodOXBoo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:998065A42A2553AF|rigid:3kGApwou6iOevV0b7eSBZbmYqLM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83568 uniprotkb:O83958 intact:EBI-1586298|ensemblbacteria:AAC26561|ensemblbacteria:AGN75744 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83568_trepa(display_long)|uniprotkb:TP_0557(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586313|imex:IM-9152-2728 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010412(Protein of unknown function DUF1007)|interpro:IPR016537(Uncharacterised conserved protein UCP008159,)|ensemblbacteria:AAC26561(transcript)|ensemblbacteria:AGN75744(transcript)|ensemblbacteria:TP_0557(gene)|ensemblbacteria:TPANIC_0557(gene)|refseq:WP_010882004.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0557; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FdELVF3vi0YE5cLgAUA1Ro7i4YE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:981C14E56ABA7B46|rigid:HNtPNyRVRMbrqZAphh4+1CVPcC0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83568 uniprotkb:O83282 intact:EBI-1586298|ensemblbacteria:AAC26561|ensemblbacteria:AGN75744 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83568_trepa(display_long)|uniprotkb:TP_0557(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586307|imex:IM-9152-2727 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010412(Protein of unknown function DUF1007)|interpro:IPR016537(Uncharacterised conserved protein UCP008159,)|ensemblbacteria:AAC26561(transcript)|ensemblbacteria:AGN75744(transcript)|ensemblbacteria:TP_0557(gene)|ensemblbacteria:TPANIC_0557(gene)|refseq:WP_010882004.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0557; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FdELVF3vi0YE5cLgAUA1Ro7i4YE243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:263F176AEDC5DD7B|rigid:NkNp1mgNhnatIRo5mLKxKJazN08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07643 uniprotkb:O83796 intact:EBI-1586327|ensemblbacteria:AAC65736 intact:EBI-1586323|ensemblbacteria:AAC65792 psi-mi:tmpa_trepa(display_long)|uniprotkb:tmpA(gene name)|psi-mi:tmpA(display_short)|uniprotkb:Membrane protein A(gene name synonym)|uniprotkb:TP_0768(locus name)|uniprotkb:Antigen TmpA(gene name synonym) psi-mi:dxs_trepa(display_long)|uniprotkb:dxs(gene name)|psi-mi:dxs(display_short)|uniprotkb:1-deoxyxylulose-5-phosphate synthase(gene name synonym)|uniprotkb:TP_0824(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586319|imex:IM-9152-2729 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65736(transcript)|ensemblbacteria:TP_0768(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010882213.1 interpro:IPR033248|interpro:IPR005477(Deoxyxylulose-5-phosphate synthase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR020826|ensemblbacteria:AAC65792(transcript)|ensemblbacteria:TP_0824(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0008661"(1-deoxy-D-xylulose-5-phosphate synthase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0052865"(1-deoxy-D-xylulose 5-phosphate biosynthetic process)|refseq:WP_010882268.1|interpro:IPR029061 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0824; PREY protein TP_0768|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JOFboMvIWFcoRVVL+x6PwCJ8v68243276 rogid:nyhKGiCHec23nIQ7Tz9yzpUU31s243276 intact-crc:147276DA28BE5091|rigid:bWzskvXcRqUuXFa92LmfrVWg8eM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83796 uniprotkb:O83958 intact:EBI-1586323|ensemblbacteria:AAC65792 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:dxs_trepa(display_long)|uniprotkb:dxs(gene name)|psi-mi:dxs(display_short)|uniprotkb:1-deoxyxylulose-5-phosphate synthase(gene name synonym)|uniprotkb:TP_0824(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586339|imex:IM-9152-2731 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033248|interpro:IPR005477(Deoxyxylulose-5-phosphate synthase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR020826|ensemblbacteria:AAC65792(transcript)|ensemblbacteria:TP_0824(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0008661"(1-deoxy-D-xylulose-5-phosphate synthase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0052865"(1-deoxy-D-xylulose 5-phosphate biosynthetic process)|refseq:WP_010882268.1|interpro:IPR029061 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0824; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nyhKGiCHec23nIQ7Tz9yzpUU31s243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:4C13157A257AD9A2|rigid:5wBrnRntWOteRooEZfQniENHe3M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83796 uniprotkb:O83970 intact:EBI-1586323|ensemblbacteria:AAC65792 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:dxs_trepa(display_long)|uniprotkb:dxs(gene name)|psi-mi:dxs(display_short)|uniprotkb:1-deoxyxylulose-5-phosphate synthase(gene name synonym)|uniprotkb:TP_0824(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586333|imex:IM-9152-2730 author score:0.681807619 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033248|interpro:IPR005477(Deoxyxylulose-5-phosphate synthase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR005475(Transketolase, central region)|interpro:IPR020826|ensemblbacteria:AAC65792(transcript)|ensemblbacteria:TP_0824(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0008661"(1-deoxy-D-xylulose-5-phosphate synthase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0052865"(1-deoxy-D-xylulose 5-phosphate biosynthetic process)|refseq:WP_010882268.1|interpro:IPR029061 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0824; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nyhKGiCHec23nIQ7Tz9yzpUU31s243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:951DDDECAA713B01|rigid:VazKJ/jBYd7W0uddgAnGziuEj4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83494 uniprotkb:O83969 intact:EBI-1584033|ensemblbacteria:AAC65470 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y481_trepa(display_long)|uniprotkb:TP_0481(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586354|imex:IM-9152-2733 author score:0.357409441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65470(transcript)|ensemblbacteria:TP_0481(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881930.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0481; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4Tpphy/4l0/ReieCOfjrpYI7w3Y243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:D38DA29496564D41|rigid:0KYdAfNVp1JUkOTg1Lss6axIowc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83934 uniprotkb:O83494 intact:EBI-1586349|ensemblbacteria:AAC65926 intact:EBI-1584033|ensemblbacteria:AAC65470 psi-mi:y968_trepa(display_long)|uniprotkb:TP_0968(locus name) psi-mi:y481_trepa(display_long)|uniprotkb:TP_0481(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586345|imex:IM-9152-2732 author score:0.798784546 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65926(transcript)|ensemblbacteria:TP_0968(gene)|refseq:WP_010882412.1 ensemblbacteria:AAC65470(transcript)|ensemblbacteria:TP_0481(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881930.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0481; PREY protein TP_0968|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bnUiwPhzNZ/mhlkGJYOYjO04XCo243276 rogid:4Tpphy/4l0/ReieCOfjrpYI7w3Y243276 intact-crc:73763203F390337E|rigid:+H66xNrjOhqm5eqxlFl7eUEpdpc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83983 uniprotkb:O83798 intact:EBI-1586373|ensemblbacteria:AAC65970 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:gata_trepa(display_long)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)|uniprotkb:TP_1020(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586369|imex:IM-9152-2735 author score:0.796455697 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412("Glutamyl-tRNA(Gln) amidotransferase A subunit")|ensemblbacteria:AAC65970(transcript)|ensemblbacteria:TP_1020(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|refseq:WP_010882464.1|interpro:IPR036928 interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_1020|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:M+KheF38jzx6H71RxIAdEJXnNfQ243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:49EC605F3DF1FF4C|rigid:n+aW5dDZ8NX6me6xQDBI3uHKXy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83494 uniprotkb:O83958 intact:EBI-1584033|ensemblbacteria:AAC65470 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y481_trepa(display_long)|uniprotkb:TP_0481(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586360|imex:IM-9152-2734 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65470(transcript)|ensemblbacteria:TP_0481(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881930.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0481; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4Tpphy/4l0/ReieCOfjrpYI7w3Y243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:592C21707F8FDEFB|rigid:rNURQFociFmhUZUSpWu99hwb1UM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83798 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586385|imex:IM-9152-2737 author score:0.289071214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:079323851A7C0534|rigid:LKj7szMCa9INtjXvQ63vXJ5RHIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83798 uniprotkb:O83970 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586379|imex:IM-9152-2736 author score:0.4769601 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:DCD660E45076B808|rigid:TkCpET3QoX/TJPfZYhCvtakLgy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83798 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586397|imex:IM-9152-2739 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:84C64A55CC1EECF6|rigid:Y0sWKRBNSDf6likFRk6GknSOM48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83798 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586391|imex:IM-9152-2738 author score:0.272759532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:9903ECA04576199A|rigid:Q2wFIyLQk+lbpiI13yiuq+1iU9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83798 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586403|imex:IM-9152-2740 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:ECD9362C66431B9F|rigid:gl+0P7xJJyY67r+FyjQqEU2EqZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83798 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586415|imex:IM-9152-2742 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:22268F97BEFE1442|rigid:NW+fVDLlsFXkdEUNDDkp1ATYir4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83798 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586409|imex:IM-9152-2741 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0826; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:444FE5B4881C51F0|rigid:MNtwEuY81DWOYR49IbInaINs6eY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83393 uniprotkb:O83048 intact:EBI-1586421|ensemblbacteria:AAC65364 intact:EBI-1198595|intact:EBI-1583590|ensemblbacteria:AAC65000 psi-mi:o83393_trepa(display_long)|uniprotkb:TP_0378(locus name) psi-mi:dpo3b_trepa(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:DNA polymerase III subunit beta(gene name synonym)|uniprotkb:TP_0002(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586424|imex:IM-9152-2743 author score:0.795857566 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65364(transcript)|ensemblbacteria:TP_0378(gene)|refseq:WP_010881826.1 interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022635|interpro:IPR022637|interpro:IPR022634|refseq:WP_010881452.1|ensemblbacteria:AAC65000(transcript)|ensemblbacteria:TP_0002(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0378; PREY protein TP_0002|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:b6klOhtsz1qbJ3/4RMbwbdd+pRY243276 rogid:4FZeat7yhkrv79CgJ0/2soG7qD4243276 intact-crc:F1DECB21EA316F1E|rigid:SJ5jDDwWqMkXzCcjoRW8rCFOsZk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83275 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586436|imex:IM-9152-2745 author score:0.795313678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0247; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:12372DE8CA8C4E49|rigid:N1Kl2Q2Mlar5dg8+qN8qzPLLgfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83393 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1586421|ensemblbacteria:AAC65364 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83393_trepa(display_long)|uniprotkb:TP_0378(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586430|imex:IM-9152-2744 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65364(transcript)|ensemblbacteria:TP_0378(gene)|refseq:WP_010881826.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0378; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:b6klOhtsz1qbJ3/4RMbwbdd+pRY243276 intact-crc:7DDD9B45FAF21672|rigid:ChvZCsI9R8woGNxE5pvahypyveU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83185 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586445|imex:IM-9152-2746 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0247; PREY protein TP_0150|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:F1785A914C125618|rigid:9OqOkC4Cw+FxciCQzrjnFGAmTQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83119 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586460|imex:IM-9152-2748 author score:0.729678219 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0247; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:65E74CCBEC5CC7EA|rigid:B1y7IvLLhFBRRGmkGUxDN0S7EcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83397 uniprotkb:O83275 intact:EBI-1586451|ensemblbacteria:AAC65383 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:y382_trepa(display_long)|uniprotkb:TP_0382(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586454|imex:IM-9152-2747 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65383(transcript)|ensemblbacteria:TP_0382(gene) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0247; PREY protein TP_0382|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vdS1NefMMjZaw7P7uLys5l3gKv8243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:865DFA28092F7D72|rigid:xnEMdNW0Vi7EzqpVo2zl1UkJMUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83062 uniprotkb:O83954 intact:EBI-1586473|ensemblbacteria:AAC65010 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:grad_trepa(display_long)|uniprotkb:TP_0018(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586478|imex:IM-9152-2750 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65010(transcript)|ensemblbacteria:TP_0018(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0018; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:t6LjcSFEmjP2m5sAMhfWz2LjdsY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4BCD5C05BD9112AF|rigid:OJe0zUAT7Fg8e5ldCp2mzIkfc0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83683 uniprotkb:O83062 intact:EBI-1586466|ensemblbacteria:AAC65653 intact:EBI-1586473|ensemblbacteria:AAC65010 psi-mi:y677_trepa(display_long)|uniprotkb:TP_0677(locus name) psi-mi:grad_trepa(display_long)|uniprotkb:TP_0018(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586469|imex:IM-9152-2749 author score:0.794422532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65653(transcript)|ensemblbacteria:TP_0677(gene)|refseq:WP_010882122.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65010(transcript)|ensemblbacteria:TP_0018(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0018; PREY protein TP_0677|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UHLVvx30vXgRFAnf6IHOfk/TsAI243276 rogid:t6LjcSFEmjP2m5sAMhfWz2LjdsY243276 intact-crc:14897440EB252944|rigid:/Gt2yhsE6tBJsVRMYUQe63hewnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83062 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586473|ensemblbacteria:AAC65010 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:grad_trepa(display_long)|uniprotkb:TP_0018(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586484|imex:IM-9152-2751 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65010(transcript)|ensemblbacteria:TP_0018(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0018; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:t6LjcSFEmjP2m5sAMhfWz2LjdsY243276 intact-crc:45BE8D7C8D0FF2B4|rigid:iAur5Tgb0BWOz4gkANXRsHFzTVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83358 uniprotkb:P74932 intact:EBI-1586490|ensemblbacteria:AAC65329 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 psi-mi:y338_trepa(display_long)|uniprotkb:TP_0338(locus name) psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586493|imex:IM-9152-2752 author score:0.794422532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65329(transcript)|ensemblbacteria:TP_0338(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881786.1 interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0338; PREY protein TP_0716|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:r/Z99q8oKW7zYECHcHQQPGg+Eks243276 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 intact-crc:463D9C1D55AE46C0|rigid:OvowycK3Okin+Wd+onhEwr3zS2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83392 uniprotkb:O83358 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 intact:EBI-1586490|ensemblbacteria:AAC65329 psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:y338_trepa(display_long)|uniprotkb:TP_0338(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586499|imex:IM-9152-2753 author score:0.752034067 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65329(transcript)|ensemblbacteria:TP_0338(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881786.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0338; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 rogid:r/Z99q8oKW7zYECHcHQQPGg+Eks243276 intact-crc:FA5A660D09109434|rigid:QdF46BdnsanWZ+NNjHjPRTkVq9Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83358 uniprotkb:O83706 intact:EBI-1586490|ensemblbacteria:AAC65329 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:y338_trepa(display_long)|uniprotkb:TP_0338(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586508|imex:IM-9152-2754 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65329(transcript)|ensemblbacteria:TP_0338(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881786.1 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0338; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:r/Z99q8oKW7zYECHcHQQPGg+Eks243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:F429642D9437C9C7|rigid:YaPbVniooE/aSHswgII/5JK5N/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83148 uniprotkb:O83753 intact:EBI-1586514|ensemblbacteria:AAC65108 intact:EBI-1198702|intact:EBI-1581572|ensemblbacteria:AAC65743|ensemblbacteria:AGN75947 psi-mi:y110_trepa(display_long)|uniprotkb:TP_0110(locus name) psi-mi:o83753_trepa(display_long)|uniprotkb:TP_0774(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586517|imex:IM-9152-2755 author score:0.794422532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65108(transcript)|ensemblbacteria:TP_0110(gene)|refseq:WP_010881559.1|interpro:IPR035196 interpro:IPR003416(MgtC/SapB transporter)|refseq:WP_010882219.1|ensemblbacteria:AAC65743(transcript)|ensemblbacteria:AGN75947(transcript)|ensemblbacteria:TP_0774(gene)|ensemblbacteria:TPANIC_0774(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0110; PREY protein TP_0774|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uSnL8d94e1v3uZO7r7N4C7ERvsw243276 rogid:CRl5LIl/mN17Ny93fonb20RY68c243276 intact-crc:D36E3A49C1FD5A6D|rigid:Xy5w7zJ6w7oRf890rdvZAJd2O4o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83148 uniprotkb:O83706 intact:EBI-1586514|ensemblbacteria:AAC65108 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:y110_trepa(display_long)|uniprotkb:TP_0110(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586523|imex:IM-9152-2756 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65108(transcript)|ensemblbacteria:TP_0110(gene)|refseq:WP_010881559.1|interpro:IPR035196 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0110; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uSnL8d94e1v3uZO7r7N4C7ERvsw243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:B167B0D11A0AAE1B|rigid:2oTLhnYRrebLGgf0Obz7vJW6s/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83148 uniprotkb:O83572 intact:EBI-1586514|ensemblbacteria:AAC65108 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y110_trepa(display_long)|uniprotkb:TP_0110(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586529|imex:IM-9152-2757 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65108(transcript)|ensemblbacteria:TP_0110(gene)|refseq:WP_010881559.1|interpro:IPR035196 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0110; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uSnL8d94e1v3uZO7r7N4C7ERvsw243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:D3FC4784CD2F431A|rigid:9rLLcr3vB1rI44LQTe7lGGnej14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83664 uniprotkb:O83552 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 intact:EBI-1586544|ensemblbacteria:AAC65525 psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:era_trepa(display_long)|uniprotkb:era(gene name)|psi-mi:era(display_short)|uniprotkb:TP_0541(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586548|imex:IM-9152-2759 author score:0.791448665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR005662(GTP-binding protein Era)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR030388|ensemblbacteria:AAC65525(transcript)|ensemblbacteria:TP_0541(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR006073(GTP1/OBG)|refseq:WP_010881988.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0541; PREY protein TP_0658|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 rogid:TlMI6LkXgl6rr0rn+yvs1myan74243276 intact-crc:487C773823752D84|rigid:l2cUnwDhSJ68YZ13LJp4NGzic5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83158 uniprotkb:O83767 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586538|imex:IM-9152-2758 author score:0.792899047 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0788; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0D8256B3409F56BA|rigid:rVCS75ghzV6ERx/0Jckl5yY0Vvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83789 uniprotkb:O83294 intact:EBI-1583765|ensemblbacteria:AAC65785 intact:EBI-1586564|ensemblbacteria:AAC65258|ensemblbacteria:AGN75481 psi-mi:y813_trepa(display_long)|uniprotkb:TP_0813(locus name) psi-mi:o83294_trepa(display_long)|uniprotkb:TP_0270(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586560|imex:IM-9152-2761 author score:0.789990817 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65785(transcript)|ensemblbacteria:TP_0813(gene) interpro:IPR002646(Polynucleotide adenylyltransferase region)|ensemblbacteria:AGN75481(transcript)|ensemblbacteria:TP_0270(gene)|ensemblbacteria:TPANIC_0270(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0016779"(nucleotidyltransferase activity)|ensemblbacteria:AAC65258(transcript)|interpro:IPR032810|interpro:IPR032828|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0270; PREY protein TP_0813|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wL71DWwNtjOq2v6Bj7n8xyMImTI243276 rogid:fcsDDNbj8NcFbJSTx894PGchpf0243276 intact-crc:C1D7C002A7A927D2|rigid:JKNVTZ7r4Qtw/UfF0qqhgP3O8xc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83552 uniprotkb:O83702 intact:EBI-1586544|ensemblbacteria:AAC65525 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:era_trepa(display_long)|uniprotkb:era(gene name)|psi-mi:era(display_short)|uniprotkb:TP_0541(locus name) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586554|imex:IM-9152-2760 author score:0.7586372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005662(GTP-binding protein Era)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR030388|ensemblbacteria:AAC65525(transcript)|ensemblbacteria:TP_0541(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR006073(GTP1/OBG)|refseq:WP_010881988.1|interpro:IPR027417 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0541; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TlMI6LkXgl6rr0rn+yvs1myan74243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:F832CCBBBDC44B05|rigid:DRrhKw63tXShUBfMKURPFIH5ha4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83294 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1586564|ensemblbacteria:AAC65258|ensemblbacteria:AGN75481 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:o83294_trepa(display_long)|uniprotkb:TP_0270(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586569|imex:IM-9152-2762 author score:0.768288447 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR002646(Polynucleotide adenylyltransferase region)|ensemblbacteria:AGN75481(transcript)|ensemblbacteria:TP_0270(gene)|ensemblbacteria:TPANIC_0270(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0016779"(nucleotidyltransferase activity)|ensemblbacteria:AAC65258(transcript)|interpro:IPR032810|interpro:IPR032828|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0270; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:fcsDDNbj8NcFbJSTx894PGchpf0243276 intact-crc:F0FFC2523E784338|rigid:HmY+LP+a71w2rv41AcWAaUIecKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83294 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1586564|ensemblbacteria:AAC65258|ensemblbacteria:AGN75481 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83294_trepa(display_long)|uniprotkb:TP_0270(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586575|imex:IM-9152-2763 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR002646(Polynucleotide adenylyltransferase region)|ensemblbacteria:AGN75481(transcript)|ensemblbacteria:TP_0270(gene)|ensemblbacteria:TPANIC_0270(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0016779"(nucleotidyltransferase activity)|ensemblbacteria:AAC65258(transcript)|interpro:IPR032810|interpro:IPR032828|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0270; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:fcsDDNbj8NcFbJSTx894PGchpf0243276 intact-crc:3CF8561C6EE0302F|rigid:ophGGKzxtuo/D3YXAO/J2243FfA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83597 uniprotkb:O83157 intact:EBI-1586588|ensemblbacteria:AAC65563 intact:EBI-1586581|ensemblbacteria:AAC65110|ensemblbacteria:AGN75339 psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:o83157_trepa(display_long)|uniprotkb:TP_0120(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586584|imex:IM-9152-2764 author score:0.789618506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 interpro:IPR026253|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65110(transcript)|ensemblbacteria:AGN75339(transcript)|ensemblbacteria:TP_0120(gene)|ensemblbacteria:TPANIC_0120(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0015821"(methionine transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881569.1|interpro:IPR027417|interpro:IPR041701 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0120|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 rogid:F7mvesFi3Y6cgLdGKx4Pl7UxPn8243276 intact-crc:F8FB39D8B1BB16B8|rigid:FNAtIFcfQPwW1e020FMoROgg8j8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83597 uniprotkb:O83170 intact:EBI-1586588|ensemblbacteria:AAC65563 intact:EBI-1586597|ensemblbacteria:AAC65125 psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:y134_trepa(display_long)|uniprotkb:TP_0134(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586593|imex:IM-9152-2765 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 ensemblbacteria:AAC65125(transcript)|ensemblbacteria:TP_0134(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881582.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0134|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 rogid:Z2YYYZZu6zrWkkkuj8sTOYMJO1k243276 intact-crc:6A62DF8797E46310|rigid:UN8b1v28cyNKJN6RbogXkQULWk0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83496 uniprotkb:O83597 intact:EBI-1586615|ensemblbacteria:AAC65472 intact:EBI-1586588|ensemblbacteria:AAC65563 psi-mi:y483_trepa(display_long)|uniprotkb:TP_0483(locus name) psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586611|imex:IM-9152-2767 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|ensemblbacteria:AAC65472(transcript)|ensemblbacteria:TP_0483(gene)|interpro:IPR036116 interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0483|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2yuFFrlSCSIRlvrqWfjos1Eb3Tg243276 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 intact-crc:ED2A8A98ED60DF04|rigid:XoC81Ri3yutUBsIHnlilP5lN96g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83597 uniprotkb:O83183 intact:EBI-1586588|ensemblbacteria:AAC65563 intact:EBI-1586606|ensemblbacteria:AAC65140 psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:y148_trepa(display_long)|uniprotkb:TP_0148(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586602|imex:IM-9152-2766 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 ensemblbacteria:AAC65140(transcript)|ensemblbacteria:TP_0148(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881595.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0148|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 rogid:Uj76HnVA1pIu+VetvJ6w7DCMeCY243276 intact-crc:A9A9D5BF715A0306|rigid:NjsA7Mkm0M5v8FYjYsSOPmM2fpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83684 uniprotkb:O83597 intact:EBI-1586620|ensemblbacteria:AAC65654 intact:EBI-1586588|ensemblbacteria:AAC65563 psi-mi:y678_trepa(display_long)|uniprotkb:TP_0678(locus name) psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586623|imex:IM-9152-2768 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65654(transcript)|ensemblbacteria:TP_0678(gene)|refseq:WP_010882123.1 interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0678|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kOHi4RAmeKItTCmoc2YbQA/TkFU243276 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 intact-crc:7E0982A6AE6F27C3|rigid:ZE9HnZKXuO4mCcdQqU6pa+xWgF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66104 uniprotkb:O83597 intact:EBI-1586629|uniprotkb:Q7DFN4 intact:EBI-1586588|ensemblbacteria:AAC65563 psi-mi:o66104_trepl(display_long)|uniprotkb:FA889_04855(orf name) psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586632|imex:IM-9152-2769 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001374(Single-stranded nucleic acid binding R3H)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR038247|interpro:IPR032782|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR034079|interpro:IPR038008|interpro:IPR036867|interpro:IPR039247|refseq:WP_010882391.1 interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0948|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:403vszGOWhHQH0wU8zA4Gq26Hto160 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 intact-crc:DC7A0953D73ACCB4|rigid:Jr4CJ7HJHhaG+8e4pjdtF6e9LQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83597 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1586588|ensemblbacteria:AAC65563 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586638|imex:IM-9152-2770 author score:0.738564161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0676|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 intact-crc:3B94E8626F2D36F5|rigid:xrvr1BftJN42Dy/F0M5ob9wQ45M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83195 uniprotkb:O83597 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 intact:EBI-1586588|ensemblbacteria:AAC65563 psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:o83597_trepa(display_long)|uniprotkb:TP_0588(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586644|imex:IM-9152-2771 author score:0.665639147 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR005790(DNA polymerase III, delta subunit)|ensemblbacteria:AAC65563(transcript)|ensemblbacteria:TP_0588(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0588; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 rogid:I91FjbXKGzX8U7d5QgU78Zr5lSA243276 intact-crc:E5E19D4C934088B1|rigid:DLRt/M4tmkHNcYSVYa2JPyDPUNU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83138 uniprotkb:O83051 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586650|imex:IM-9152-2772 author score:0.788543381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0100; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 intact-crc:C67078EE767123B9|rigid:D8caqnkftd9uueisjyroWkDS+Mk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83138 uniprotkb:O83804 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586662|imex:IM-9152-2774 author score:0.570574749 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0100; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:F94A8FF9B2485672|rigid:WyZDOD7+w19Mrq85b3ivPCX1IbY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83138 uniprotkb:O83126 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586656|imex:IM-9152-2773 author score:0.743635035 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0100; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:E3F79A1A1C1EC45E|rigid:EKM2w1un3xVqUMJSfnjfJ7fI5p0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83138 uniprotkb:O83954 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586674|imex:IM-9152-2776 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0100; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:B2627606A60F8EBC|rigid:eobS7ZQDWI7XkVa2uIAGWmJDrEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83138 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586668|imex:IM-9152-2775 author score:0.361754444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0100; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 intact-crc:57637A4C7EACDF76|rigid:KKfGuxN9oWFz1VTDtaG+3Bwq30g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83079 uniprotkb:O83706 intact:EBI-1586680|ensemblbacteria:AAC65031 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:y036_trepa(display_long)|uniprotkb:TP_0036(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586683|imex:IM-9152-2777 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001626(ABC-3)|ensemblbacteria:AAC65031(transcript)|ensemblbacteria:TP_0036(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|refseq:WP_010881485.1|interpro:IPR037294 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0708; PREY protein TP_0036|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:c0I8SrM7uCvFiIAIeEx0w2T9LPc243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:2B7D89E29A42877F|rigid:g044nvpRd/hhyi+cg/JLnXHLsYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O83706 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586689|imex:IM-9152-2778 author score:0.729678219 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0708; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:CAA0A86DC66B3631|rigid:X5IVjLLsOb3Bkh1Io/2WnRQTaZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O83887 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586701|imex:IM-9152-2780 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0708; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:2F2180DE9CE66091|rigid:wFrAMsToRUWtBdqIXtBr41IU7yM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83706 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586695|imex:IM-9152-2779 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0708; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:4A7ED9772B5308BD|rigid:rnqy2JTv5qTldrAKHAunEhhME9k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06686 uniprotkb:O83839 intact:EBI-1586713|uniprotkb:Q7DFP8 intact:EBI-1583317|ensemblbacteria:AAC65845 psi-mi:o06686_trepl(display_long)|uniprotkb:FA889_01180(orf name) psi-mi:y869_trepa(display_long)|uniprotkb:TP_0869(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586716|imex:IM-9152-2782 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6MLX|interpro:IPR026906|interpro:IPR032675|refseq:WP_010881673.1 ensemblbacteria:AAC65845(transcript)|ensemblbacteria:TP_0869(gene)|refseq:WP_010882312.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0869; PREY protein TP_0225|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mpR2IjBlohP7UHj/JdxS2qfVado160 rogid:GgRpxAbLBOBoLmeVcfxuPlg6cVo243276 intact-crc:BE4EC6D209D663FB|rigid:bcwQQXqsP0CDmGRyQS1yjg6EgSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83839 uniprotkb:O83161 intact:EBI-1583317|ensemblbacteria:AAC65845 intact:EBI-1585006|ensemblbacteria:AAC65113|ensemblbacteria:AGN75343 psi-mi:y869_trepa(display_long)|uniprotkb:TP_0869(locus name) psi-mi:o83161_trepa(display_long)|uniprotkb:ychF(gene name)|psi-mi:ychF(display_short)|uniprotkb:TP_0124(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586707|imex:IM-9152-2781 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65845(transcript)|ensemblbacteria:TP_0869(gene)|refseq:WP_010882312.1 interpro:IPR031167|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012676(TGS-like)|interpro:IPR023192|ensemblbacteria:AAC65113(transcript)|ensemblbacteria:TP_0124(gene)|ensemblbacteria:TPANIC_0124(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|ensemblbacteria:AGN75343(transcript)|refseq:WP_010881573.1|interpro:IPR027417|interpro:IPR041706 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0869; PREY protein TP_0124|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GgRpxAbLBOBoLmeVcfxuPlg6cVo243276 rogid:S3UXAYFC48deDsMOxZDAI+c09Do243276 intact-crc:638DCB964C847435|rigid:KPKx+7si2j39RvePr0/k45mPtIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83238 uniprotkb:O83839 intact:EBI-1585669|ensemblbacteria:AAC65198 intact:EBI-1583317|ensemblbacteria:AAC65845 psi-mi:o83238_trepa(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TP_0208(locus name) psi-mi:y869_trepa(display_long)|uniprotkb:TP_0869(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586722|imex:IM-9152-2783 author score:0.784001225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|ensemblbacteria:AAC65198(transcript)|ensemblbacteria:TP_0208(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881656.1 ensemblbacteria:AAC65845(transcript)|ensemblbacteria:TP_0869(gene)|refseq:WP_010882312.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0869; PREY protein TP_0208|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:lEmXcpm7ehHfYtWFoAIjCA8/aYA243276 rogid:GgRpxAbLBOBoLmeVcfxuPlg6cVo243276 intact-crc:58B1917ABDCC4824|rigid:KmEJ93Q7XQgFS0wI3+DPJGA5NQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83699 uniprotkb:O83839 intact:EBI-1586728|ensemblbacteria:AAC65670 intact:EBI-1583317|ensemblbacteria:AAC65845 psi-mi:rpoz_trepa(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:TP_0701(locus name) psi-mi:y869_trepa(display_long)|uniprotkb:TP_0869(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586732|imex:IM-9152-2784 author score:0.779407236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006110(RNA polymerase Rpb6)|ensemblbacteria:AAC65670(transcript)|ensemblbacteria:TP_0701(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|refseq:WP_010882146.1|interpro:IPR036161 ensemblbacteria:AAC65845(transcript)|ensemblbacteria:TP_0869(gene)|refseq:WP_010882312.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0869; PREY protein TP_0701|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qImQ7fWBJEGqpSutHzSZ0CANeg0243276 rogid:GgRpxAbLBOBoLmeVcfxuPlg6cVo243276 intact-crc:BAA8B2A0D612A7D5|rigid:8zEAa06B78BEFaFKvgMNHYyzoVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83569 uniprotkb:O83262 intact:EBI-1586746|ensemblbacteria:AAC26562|ensemblbacteria:AGN75745 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:o83569_trepa(display_long)|uniprotkb:TP_0558(locus name) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586742|imex:IM-9152-2785 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011541(Nickel/cobalt transporter, high-affinity)|ensemblbacteria:AGN75745(transcript)|ensemblbacteria:AAC26562(transcript)|ensemblbacteria:TP_0558(gene)|ensemblbacteria:TPANIC_0558(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015099"(nickel cation transmembrane transporter activity)|refseq:WP_010882005.1 interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0558; PREY protein TP_0234|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fxi85KeoPfIaDts7yU9GC6g1xbY243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:B10181487CBD2FE8|rigid:KHGxvt4xhQ3HJ2+IL+S831yVIyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83298 uniprotkb:O83569 intact:EBI-1586755|ensemblbacteria:AAC65262|ensemblbacteria:AGN75485 intact:EBI-1586746|ensemblbacteria:AAC26562|ensemblbacteria:AGN75745 psi-mi:o83298_trepa(display_long)|uniprotkb:TP_0274(locus name) psi-mi:o83569_trepa(display_long)|uniprotkb:TP_0558(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586751|imex:IM-9152-2786 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR015517(Cytidine deaminase)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR016473(dCMP deaminase)|ensemblbacteria:AAC65262(transcript)|ensemblbacteria:AGN75485(transcript)|ensemblbacteria:TP_0274(gene)|ensemblbacteria:TPANIC_0274(gene)|go:"GO:0004132"(dCMP deaminase activity)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0008270"(zinc ion binding)|refseq:WP_010881723.1|interpro:IPR035105 interpro:IPR011541(Nickel/cobalt transporter, high-affinity)|ensemblbacteria:AGN75745(transcript)|ensemblbacteria:AAC26562(transcript)|ensemblbacteria:TP_0558(gene)|ensemblbacteria:TPANIC_0558(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015099"(nickel cation transmembrane transporter activity)|refseq:WP_010882005.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0558; PREY protein TP_0274|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MWjQYiwLE46hhco/u1nuNIBTEZo243276 rogid:fxi85KeoPfIaDts7yU9GC6g1xbY243276 intact-crc:0315A36A2E980F35|rigid:tTfhRoLV+tIM2dPdhDsVdm2wc2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83569 uniprotkb:O83572 intact:EBI-1586746|ensemblbacteria:AAC26562|ensemblbacteria:AGN75745 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83569_trepa(display_long)|uniprotkb:TP_0558(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586760|imex:IM-9152-2787 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011541(Nickel/cobalt transporter, high-affinity)|ensemblbacteria:AGN75745(transcript)|ensemblbacteria:AAC26562(transcript)|ensemblbacteria:TP_0558(gene)|ensemblbacteria:TPANIC_0558(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015099"(nickel cation transmembrane transporter activity)|refseq:WP_010882005.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0558; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fxi85KeoPfIaDts7yU9GC6g1xbY243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:B8F486F77A9C3B99|rigid:ST2bF+WvmYjawgYfFLsGwXIgKuQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83569 uniprotkb:O83887 intact:EBI-1586746|ensemblbacteria:AAC26562|ensemblbacteria:AGN75745 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83569_trepa(display_long)|uniprotkb:TP_0558(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586766|imex:IM-9152-2788 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011541(Nickel/cobalt transporter, high-affinity)|ensemblbacteria:AGN75745(transcript)|ensemblbacteria:AAC26562(transcript)|ensemblbacteria:TP_0558(gene)|ensemblbacteria:TPANIC_0558(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015099"(nickel cation transmembrane transporter activity)|refseq:WP_010882005.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0558; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fxi85KeoPfIaDts7yU9GC6g1xbY243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:8ABBD07E0F72EA2B|rigid:NLXZkoYKga+SUcXQBvifyQWJa5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83365 uniprotkb:O83435 intact:EBI-1586772|ensemblbacteria:AAC65333 intact:EBI-1586776|ensemblbacteria:AAC65408 psi-mi:mray_trepa(display_long)|uniprotkb:mraY(gene name)|psi-mi:mraY(display_short)|uniprotkb:UDP-MurNAc-pentapeptide phosphotransferase(gene name synonym)|uniprotkb:TP_0345(locus name) psi-mi:y420_trepa(display_long)|uniprotkb:TP_0420(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586779|imex:IM-9152-2789 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR003524(Phospho-N-acetylmuramoyl-pentapeptide transferase)|interpro:IPR018480|ensemblbacteria:AAC65333(transcript)|ensemblbacteria:TP_0345(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051992"("UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity")|go:"GO:0071555"(cell wall organization)|refseq:WP_010881793.1 ensemblbacteria:AAC65408(transcript)|ensemblbacteria:TP_0420(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0345; PREY protein TP_0420|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:I1f7uyR3f4nRVlsQ1beCdD3UmWI243276 rogid:28WJ//MZ2zAQ0EQP10MGPs7jKN0243276 intact-crc:131643C87D57D5A0|rigid:Sz2IgdjjG1604wuatzch4U3l3k8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83365 uniprotkb:O83239 intact:EBI-1586772|ensemblbacteria:AAC65333 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:mray_trepa(display_long)|uniprotkb:mraY(gene name)|psi-mi:mraY(display_short)|uniprotkb:UDP-MurNAc-pentapeptide phosphotransferase(gene name synonym)|uniprotkb:TP_0345(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586785|imex:IM-9152-2790 author score:0.649325558 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR003524(Phospho-N-acetylmuramoyl-pentapeptide transferase)|interpro:IPR018480|ensemblbacteria:AAC65333(transcript)|ensemblbacteria:TP_0345(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051992"("UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity")|go:"GO:0071555"(cell wall organization)|refseq:WP_010881793.1 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0345; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:I1f7uyR3f4nRVlsQ1beCdD3UmWI243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:FAFF243F23C12BE5|rigid:CwQVZLT/e168IzbGocVxXJ4yI24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83365 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1586772|ensemblbacteria:AAC65333 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:mray_trepa(display_long)|uniprotkb:mraY(gene name)|psi-mi:mraY(display_short)|uniprotkb:UDP-MurNAc-pentapeptide phosphotransferase(gene name synonym)|uniprotkb:TP_0345(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586791|imex:IM-9152-2791 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR003524(Phospho-N-acetylmuramoyl-pentapeptide transferase)|interpro:IPR018480|ensemblbacteria:AAC65333(transcript)|ensemblbacteria:TP_0345(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051992"("UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity")|go:"GO:0071555"(cell wall organization)|refseq:WP_010881793.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0345; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:I1f7uyR3f4nRVlsQ1beCdD3UmWI243276 intact-crc:2F12A7E638BB33C2|rigid:p6Y191ar0KS45FK7fdW4M0Q7nQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83365 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1586772|ensemblbacteria:AAC65333 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:mray_trepa(display_long)|uniprotkb:mraY(gene name)|psi-mi:mraY(display_short)|uniprotkb:UDP-MurNAc-pentapeptide phosphotransferase(gene name synonym)|uniprotkb:TP_0345(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586797|imex:IM-9152-2792 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR000715(Glycosyl transferase, family 4)|interpro:IPR003524(Phospho-N-acetylmuramoyl-pentapeptide transferase)|interpro:IPR018480|ensemblbacteria:AAC65333(transcript)|ensemblbacteria:TP_0345(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008963"(phospho-N-acetylmuramoyl-pentapeptide-transferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051992"("UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity")|go:"GO:0071555"(cell wall organization)|refseq:WP_010881793.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0345; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:I1f7uyR3f4nRVlsQ1beCdD3UmWI243276 intact-crc:1D5DF16F4D55E270|rigid:qHEXprXYSOsVZI+ZkR2c229CtQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83517 uniprotkb:P96117 intact:EBI-1586811|ensemblbacteria:AAC65493 intact:EBI-1586807|ensemblbacteria:AAC65154 psi-mi:y504_trepa(display_long)|uniprotkb:TP_0504(locus name) psi-mi:trob_trepa(display_long)|uniprotkb:troB(gene name)|psi-mi:troB(display_short)|uniprotkb:TP_0164(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586803|imex:IM-9152-2793 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65493(transcript)|ensemblbacteria:TP_0504(gene) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65154(transcript)|ensemblbacteria:TP_0164(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006829"(zinc ion transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR027417|refseq:WP_010881611.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0164; PREY protein TP_0504|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:n9QSzS7951L1x/g+DzdsDg+Mu/Y243276 rogid:Jg95//qzy6XG9U89lCN5VRlMzG8243276 intact-crc:FEDA8709A8AB8F4E|rigid:3Yf7hLrY9uPq0URU6H8K6eopjms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96117 uniprotkb:O83745 intact:EBI-1586807|ensemblbacteria:AAC65154 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:trob_trepa(display_long)|uniprotkb:troB(gene name)|psi-mi:troB(display_short)|uniprotkb:TP_0164(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586822|imex:IM-9152-2795 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65154(transcript)|ensemblbacteria:TP_0164(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006829"(zinc ion transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR027417|refseq:WP_010881611.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0164; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Jg95//qzy6XG9U89lCN5VRlMzG8243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:DF8D7B7A8AAA56A7|rigid:3FfZoMA5OHfKwW2BKVGcf51/X58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83814 uniprotkb:P96117 intact:EBI-1582504|ensemblbacteria:AAC65810 intact:EBI-1586807|ensemblbacteria:AAC65154 psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:trob_trepa(display_long)|uniprotkb:troB(gene name)|psi-mi:troB(display_short)|uniprotkb:TP_0164(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586816|imex:IM-9152-2794 author score:0.779407236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65154(transcript)|ensemblbacteria:TP_0164(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006829"(zinc ion transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR027417|refseq:WP_010881611.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0164; PREY protein TP_0842|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 rogid:Jg95//qzy6XG9U89lCN5VRlMzG8243276 intact-crc:6284A3F995717A7B|rigid:zaJcfMUkFmAfoD9FocLsW4cx9tU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P96117 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586807|ensemblbacteria:AAC65154 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:trob_trepa(display_long)|uniprotkb:troB(gene name)|psi-mi:troB(display_short)|uniprotkb:TP_0164(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586828|imex:IM-9152-2796 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65154(transcript)|ensemblbacteria:TP_0164(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006829"(zinc ion transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR027417|refseq:WP_010881611.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0164; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Jg95//qzy6XG9U89lCN5VRlMzG8243276 intact-crc:A23463EC429560C5|rigid:oYQPmSHUE4i5MOL2RmpwMYstABs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83319 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1586834|ensemblbacteria:AAC65285 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:coae_trepa(display_long)|uniprotkb:coaE(gene name)|psi-mi:coaE(display_short)|uniprotkb:Dephosphocoenzyme A kinase(gene name synonym)|uniprotkb:TP_0296(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586847|imex:IM-9152-2798 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR001977(Dephospho-CoA kinase)|ensemblbacteria:AAC65285(transcript)|ensemblbacteria:TP_0296(gene)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|refseq:WP_010881745.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0296; PREY protein TP_0578|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:IpMKeSnKQejKlUTyIx4s2E9YafU243276 intact-crc:D60D4DAD3309C09F|rigid:iSpm5eS+DXdyIbN/M7uJbTNjVjw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83568 uniprotkb:O83319 intact:EBI-1586298|ensemblbacteria:AAC26561|ensemblbacteria:AGN75744 intact:EBI-1586834|ensemblbacteria:AAC65285 psi-mi:o83568_trepa(display_long)|uniprotkb:TP_0557(locus name) psi-mi:coae_trepa(display_long)|uniprotkb:coaE(gene name)|psi-mi:coaE(display_short)|uniprotkb:Dephosphocoenzyme A kinase(gene name synonym)|uniprotkb:TP_0296(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586838|imex:IM-9152-2797 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010412(Protein of unknown function DUF1007)|interpro:IPR016537(Uncharacterised conserved protein UCP008159,)|ensemblbacteria:AAC26561(transcript)|ensemblbacteria:AGN75744(transcript)|ensemblbacteria:TP_0557(gene)|ensemblbacteria:TPANIC_0557(gene)|refseq:WP_010882004.1 interpro:IPR001977(Dephospho-CoA kinase)|ensemblbacteria:AAC65285(transcript)|ensemblbacteria:TP_0296(gene)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|refseq:WP_010881745.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0296; PREY protein TP_0557|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FdELVF3vi0YE5cLgAUA1Ro7i4YE243276 rogid:IpMKeSnKQejKlUTyIx4s2E9YafU243276 intact-crc:AC9D6CE75ED0C7BC|rigid:0OPzus3oAHQ52I1mPoFU4OW4QFs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83600 uniprotkb:O83319 intact:EBI-1586853|ensemblbacteria:AAC65566 intact:EBI-1586834|ensemblbacteria:AAC65285 psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:coae_trepa(display_long)|uniprotkb:coaE(gene name)|psi-mi:coaE(display_short)|uniprotkb:Dephosphocoenzyme A kinase(gene name synonym)|uniprotkb:TP_0296(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586857|imex:IM-9152-2799 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 interpro:IPR001977(Dephospho-CoA kinase)|ensemblbacteria:AAC65285(transcript)|ensemblbacteria:TP_0296(gene)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|refseq:WP_010881745.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0296; PREY protein TP_0591|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 rogid:IpMKeSnKQejKlUTyIx4s2E9YafU243276 intact-crc:3AE5E2FA99F5B7FD|rigid:92ByL30RMwNjS+f+YHvTRmcbjxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83319 uniprotkb:O83927 intact:EBI-1586834|ensemblbacteria:AAC65285 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:coae_trepa(display_long)|uniprotkb:coaE(gene name)|psi-mi:coaE(display_short)|uniprotkb:Dephosphocoenzyme A kinase(gene name synonym)|uniprotkb:TP_0296(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586863|imex:IM-9152-2800 author score:0.285262571 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001977(Dephospho-CoA kinase)|ensemblbacteria:AAC65285(transcript)|ensemblbacteria:TP_0296(gene)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process)|refseq:WP_010881745.1|interpro:IPR027417 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0296; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IpMKeSnKQejKlUTyIx4s2E9YafU243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:C940171B071950DA|rigid:QhJ+xLH3S0xsqAhwMU3byWzqEZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83215 uniprotkb:O83650 intact:EBI-1586144|ensemblbacteria:AAC65170|ensemblbacteria:AGN75399 intact:EBI-1586873|ensemblbacteria:AAC65618 psi-mi:o83215_trepa(display_long)|uniprotkb:TP_0185(locus name) psi-mi:syk_trepa(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0644(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586869|imex:IM-9152-2801 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000223(Peptidase S26A, signal peptidase I)|ensemblbacteria:AAC65170(transcript)|ensemblbacteria:AGN75399(transcript)|ensemblbacteria:TP_0185(gene)|ensemblbacteria:TPANIC_0185(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881632.1|interpro:IPR036286|interpro:IPR019533 interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002904(Lysyl-tRNA synthetase, class Ic, archaeal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65618(transcript)|ensemblbacteria:TP_0644(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation)|refseq:WP_010882089.1|interpro:IPR042078 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0185; PREY protein TP_0644|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OpqygOQJ4r+cTeqT0R3CKdk8sVk243276 rogid:1iKQyXCF8vSJ0ysGig7WLZZXQcw243276 intact-crc:8A9669928AB6C6B9|rigid:Xl1cOpsqS56Ysi7fnURZZ8oqQqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83215 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1586144|ensemblbacteria:AAC65170|ensemblbacteria:AGN75399 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83215_trepa(display_long)|uniprotkb:TP_0185(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586879|imex:IM-9152-2802 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR000223(Peptidase S26A, signal peptidase I)|ensemblbacteria:AAC65170(transcript)|ensemblbacteria:AGN75399(transcript)|ensemblbacteria:TP_0185(gene)|ensemblbacteria:TPANIC_0185(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881632.1|interpro:IPR036286|interpro:IPR019533 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0185; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:OpqygOQJ4r+cTeqT0R3CKdk8sVk243276 intact-crc:98A6AD54F7B159D0|rigid:IlLn3eEEsdtsPGhyJYpu24c5I3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83215 uniprotkb:O83767 intact:EBI-1586144|ensemblbacteria:AAC65170|ensemblbacteria:AGN75399 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83215_trepa(display_long)|uniprotkb:TP_0185(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586885|imex:IM-9152-2803 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000223(Peptidase S26A, signal peptidase I)|ensemblbacteria:AAC65170(transcript)|ensemblbacteria:AGN75399(transcript)|ensemblbacteria:TP_0185(gene)|ensemblbacteria:TPANIC_0185(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881632.1|interpro:IPR036286|interpro:IPR019533 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0185; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OpqygOQJ4r+cTeqT0R3CKdk8sVk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:5F908CA6B03ABF48|rigid:jteLbHTk9ULrgxKaOMbs7OxhvLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83477 uniprotkb:O83721 intact:EBI-1198486|intact:EBI-1586897|ensemblbacteria:AAC65448 intact:EBI-1586911|ensemblbacteria:AGN75913|ensemblbacteria:AAC65707 psi-mi:trmb_trepa(display_long)|uniprotkb:trmB(gene name)|psi-mi:trmB(display_short)|uniprotkb:TP_0464(locus name)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym) psi-mi:o83721_trepa(display_long)|uniprotkb:TP_0739(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586914|imex:IM-9152-2806 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003358(Putative methyltransferase)|interpro:IPR029063|refseq:WP_010881913.1|ensemblbacteria:AAC65448(transcript)|ensemblbacteria:TP_0464(gene)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity") interpro:IPR004474(Cell envelope-related transcriptional attenuator)|ensemblbacteria:AAC65707(transcript)|ensemblbacteria:AGN75913(transcript)|ensemblbacteria:TP_0739(gene)|ensemblbacteria:TPANIC_0739(gene)|refseq:WP_010882184.1|interpro:IPR027381 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0464; PREY protein TP_0739|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XJD+Mu1KYGriNG8566hx1IKzm9Y243276 rogid:i2D9xp91VVSHufLpK1JhOHaeFeA243276 intact-crc:A40E8ACDAC010B9F|rigid:KwPU9FV2PGbZDGfXmYIBxoq++Ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83477 uniprotkb:Q56340 intact:EBI-1198486|intact:EBI-1586897|ensemblbacteria:AAC65448 intact:EBI-1198495|intact:EBI-1586901|uniprotkb:Q7DFP1 psi-mi:trmb_trepa(display_long)|uniprotkb:trmB(gene name)|psi-mi:trmB(display_short)|uniprotkb:TP_0464(locus name)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym) psi-mi:q56340_trepl(display_long)|uniprotkb:orf304(gene name)|psi-mi:orf304(display_short)|uniprotkb:FA889_03690(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586905|imex:IM-9152-2805 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003358(Putative methyltransferase)|interpro:IPR029063|refseq:WP_010881913.1|ensemblbacteria:AAC65448(transcript)|ensemblbacteria:TP_0464(gene)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity") interpro:IPR002586(Cobyrinic acid a,c-diamide synthase)|interpro:IPR027417|interpro:IPR033875|go:"GO:0005524"(ATP binding)|interpro:IPR025501 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0464; PREY protein TP_0712|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XJD+Mu1KYGriNG8566hx1IKzm9Y243276 rogid:9axfxY7V3wp6mmkWL5AC9Kl7pvY160 intact-crc:D9AC995351A49CB5|rigid:2r5YMWCDkHA2ExiT1OsSGIddUAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83215 uniprotkb:O83745 intact:EBI-1586144|ensemblbacteria:AAC65170|ensemblbacteria:AGN75399 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83215_trepa(display_long)|uniprotkb:TP_0185(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586891|imex:IM-9152-2804 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000223(Peptidase S26A, signal peptidase I)|ensemblbacteria:AAC65170(transcript)|ensemblbacteria:AGN75399(transcript)|ensemblbacteria:TP_0185(gene)|ensemblbacteria:TPANIC_0185(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881632.1|interpro:IPR036286|interpro:IPR019533 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0185; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OpqygOQJ4r+cTeqT0R3CKdk8sVk243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:FD4348BBF498A60F|rigid:zn7+BxaJfhRY4VHtt9Jk9hbx01w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83477 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198486|intact:EBI-1586897|ensemblbacteria:AAC65448 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:trmb_trepa(display_long)|uniprotkb:trmB(gene name)|psi-mi:trmB(display_short)|uniprotkb:TP_0464(locus name)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586926|imex:IM-9152-2808 author score:0.325184226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR003358(Putative methyltransferase)|interpro:IPR029063|refseq:WP_010881913.1|ensemblbacteria:AAC65448(transcript)|ensemblbacteria:TP_0464(gene)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0464; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:XJD+Mu1KYGriNG8566hx1IKzm9Y243276 intact-crc:422459D554AD1E77|rigid:f+IbzZvaOidhxZ0IovIuh63VOVA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83477 uniprotkb:O83804 intact:EBI-1198486|intact:EBI-1586897|ensemblbacteria:AAC65448 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:trmb_trepa(display_long)|uniprotkb:trmB(gene name)|psi-mi:trmB(display_short)|uniprotkb:TP_0464(locus name)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586920|imex:IM-9152-2807 author score:0.585853792 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003358(Putative methyltransferase)|interpro:IPR029063|refseq:WP_010881913.1|ensemblbacteria:AAC65448(transcript)|ensemblbacteria:TP_0464(gene)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity") interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0464; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XJD+Mu1KYGriNG8566hx1IKzm9Y243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:498872E6E0E29E1C|rigid:DAeVxOR+bfQ41WUYx7NZxmm6Gx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83828 uniprotkb:O83398 intact:EBI-1586932|ensemblbacteria:AAC65828 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y856_trepa(display_long)|uniprotkb:TP_0856(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586935|imex:IM-9152-2809 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65828(transcript)|ensemblbacteria:TP_0856(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0383; PREY protein TP_0856|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yWQHb9hzPMZ1HBvQbPI4IcndhHY243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:CB81201540F7822D|rigid:fghOS+7bR6WEbcc2N8CwxO7fBYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83908 uniprotkb:O83398 intact:EBI-1586941|ensemblbacteria:AAC65898 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y938_trepa(display_long)|uniprotkb:TP_0938(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586944|imex:IM-9152-2810 author score:0.7885255 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65898(transcript)|ensemblbacteria:TP_0938(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010882381.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0383; PREY protein TP_0938|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VB33+7NO6EKkQQTVn6kdVyGdPiY243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:7C12B7951888261E|rigid:OQbCQ3O1pZZJ3I7D00k0ntQ57NM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83398 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586956|imex:IM-9152-2812 author score:0.399636927 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0383; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:10587485031D0160|rigid:OJFgYeV36LaVDig3JfU8Jeend+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O66107 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586950|imex:IM-9152-2811 author score:0.685164959 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0383; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:F14A6CE32AA5B788|rigid:q7TllbipK658AaJFY+3MCySgRQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83977 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1583534|ensemblbacteria:AAC65964 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586962|imex:IM-9152-2813 author score:0.788443236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1013; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 intact-crc:D7A858FCCB71643A|rigid:XmkJY0t5nvkSsQrAYGisP1VBikc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83217 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1586972|ensemblbacteria:AAC65172 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:eftu_trepa(display_long)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)|uniprotkb:TP_0187(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586968|imex:IM-9152-2814 author score:0.7854602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR031157|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR033720|ensemblbacteria:AAC65172(transcript)|ensemblbacteria:TP_0187(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0003924"(GTPase activity)|refseq:WP_010881634.1|interpro:IPR027417|interpro:IPR041709 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0187; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:pZG1DZTEpJlreYRbOmqHkI/QJcU243276 intact-crc:FB8B58336B154DB3|rigid:XXSmUUdEniyzFlRtvr7MooXEykM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83217 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1586972|ensemblbacteria:AAC65172 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:eftu_trepa(display_long)|uniprotkb:tuf(gene name)|psi-mi:tuf(display_short)|uniprotkb:TP_0187(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586978|imex:IM-9152-2815 author score:0.733139527 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR031157|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR033720|ensemblbacteria:AAC65172(transcript)|ensemblbacteria:TP_0187(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0003924"(GTPase activity)|refseq:WP_010881634.1|interpro:IPR027417|interpro:IPR041709 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0187; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:pZG1DZTEpJlreYRbOmqHkI/QJcU243276 intact-crc:6672BDA80C303DE2|rigid:M+hOtjh019iVucl7IPRdkmpxMgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83575 uniprotkb:O83681 intact:EBI-1586984|ensemblbacteria:AAC65547 intact:EBI-1198521|intact:EBI-1586987|ensemblbacteria:AAC65651 psi-mi:y564_trepa(display_long)|uniprotkb:TP_0564(locus name) psi-mi:y675_trepa(display_long)|uniprotkb:TP_0675(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586990|imex:IM-9152-2816 author score:0.784001225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65547(transcript)|ensemblbacteria:TP_0564(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882011.1 interpro:IPR002816(Pheromone shutdown-related, TraB)|refseq:WP_010882120.1|ensemblbacteria:AAC65651(transcript)|ensemblbacteria:TP_0675(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0564; PREY protein TP_0675|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UZGkncROAQcLIuZOQYKyxAv/yaM243276 rogid:2TmSwpa+jeHRVL+79cLSlWwNcyg243276 intact-crc:CEF79EB99E8A7FC5|rigid:jAuXoEnx8fkdeoRSrixZwEu9Tr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83575 uniprotkb:O83572 intact:EBI-1586984|ensemblbacteria:AAC65547 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y564_trepa(display_long)|uniprotkb:TP_0564(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1586996|imex:IM-9152-2817 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65547(transcript)|ensemblbacteria:TP_0564(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882011.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0564; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UZGkncROAQcLIuZOQYKyxAv/yaM243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:81CEB8D1B2BE6E9F|rigid:a0Ly4NeSR8FRPjfcPGzwzePBlF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83575 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1586984|ensemblbacteria:AAC65547 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y564_trepa(display_long)|uniprotkb:TP_0564(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587002|imex:IM-9152-2818 author score:0.505945088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65547(transcript)|ensemblbacteria:TP_0564(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882011.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0564; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:UZGkncROAQcLIuZOQYKyxAv/yaM243276 intact-crc:891131A84F7379CE|rigid:8bYOvrYsAx0QyxoT38ahpEUw1Fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07885 uniprotkb:O83891 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 intact:EBI-1587014|ensemblbacteria:AAC65876|ensemblbacteria:AGN76088 psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:o83891_trepa(display_long)|uniprotkb:TP_0921(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587017|imex:IM-9152-2820 author score:0.782421663 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|ensemblbacteria:AAC65876(transcript)|ensemblbacteria:AGN76088(transcript)|ensemblbacteria:TP_0921(gene)|ensemblbacteria:TPANIC_0921(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:WP_010882364.1|interpro:IPR036188 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0921; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 rogid:cYia3EXIIpeh2Uu3oUfU9eI7LPw243276 intact-crc:2C206E9D11B54BA4|rigid:4voXhArDIQJ2o5ll3YNam08xwS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83575 uniprotkb:O83958 intact:EBI-1586984|ensemblbacteria:AAC65547 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y564_trepa(display_long)|uniprotkb:TP_0564(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587008|imex:IM-9152-2819 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65547(transcript)|ensemblbacteria:TP_0564(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882011.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0564; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UZGkncROAQcLIuZOQYKyxAv/yaM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:315D1BBA0CF151E3|rigid:LSugtRh+W1dVNXdzzW8YHbDcdDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83083 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1587036|ensemblbacteria:AAC65037|ensemblbacteria:AGN75263 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:o83083_trepa(display_long)|uniprotkb:TP_0043(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587032|imex:IM-9152-2822 author score:0.78231978 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) interpro:IPR023346|interpro:IPR008258(Lytic transglycosylase-like, catalytic)|ensemblbacteria:AAC65037(transcript)|ensemblbacteria:AGN75263(transcript)|ensemblbacteria:TP_0043(gene)|ensemblbacteria:TPANIC_0043(gene)|refseq:WP_010881492.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0043|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:L5c/hn/KYHaZ7OiMJh6wEgilZZg243276 intact-crc:1F10B78A17224031|rigid:rex39WkvCRESjcfYsp5BLeLCmFQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83891 uniprotkb:O83767 intact:EBI-1587014|ensemblbacteria:AAC65876|ensemblbacteria:AGN76088 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83891_trepa(display_long)|uniprotkb:TP_0921(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587023|imex:IM-9152-2821 author score:0.110516645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR023753|ensemblbacteria:AAC65876(transcript)|ensemblbacteria:AGN76088(transcript)|ensemblbacteria:TP_0921(gene)|ensemblbacteria:TPANIC_0921(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:WP_010882364.1|interpro:IPR036188 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0921; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cYia3EXIIpeh2Uu3oUfU9eI7LPw243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:021366DD22BF822D|rigid:Ph3UtjzIa4P27YSiymlPabiV2iE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83268 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1582146|ensemblbacteria:AAC65228 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:rl7_trepa(display_long)|uniprotkb:rplL(gene name)|psi-mi:rplL(display_short)|uniprotkb:TP_0240(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587041|imex:IM-9152-2823 author score:0.774721864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|ensemblbacteria:AAC65228(transcript)|ensemblbacteria:TP_0240(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881688.1|interpro:IPR036235 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0240|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:z8V8m1op++Un5wCNg5xzxqKCGQI243276 intact-crc:DA927FD8031991D3|rigid:QgbbXcjvWzS4C2vGcCQoCaDC17E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83814 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1582504|ensemblbacteria:AAC65810 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587047|imex:IM-9152-2824 author score:0.769650842 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0842|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 intact-crc:B8FF20991A31BFC0|rigid:uUmclrUENi2a7WV8xilSpIMlZ3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83997 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587066|imex:IM-9152-2826 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0903|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 intact-crc:9FE73DA27E0EE65D|rigid:jCifeG+aOLQTn1/MzjuN0Np1hSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83352 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1587057|ensemblbacteria:AAC65327 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:y332_trepa(display_long)|uniprotkb:TP_0332(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587053|imex:IM-9152-2825 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) ensemblbacteria:AAC65327(transcript)|ensemblbacteria:TP_0332(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0332|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:ieIaWyG3hW00yFjyVgUoFVY3JyU243276 intact-crc:707CC4926081037A|rigid:uR/2jtH5AOMLLMNNaKnm9mfSNSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83293 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1583512|ensemblbacteria:AAC65257 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:mtab_trepa(display_long)|uniprotkb:mtaB(gene name)|psi-mi:mtaB(display_short)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0269(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587072|imex:IM-9152-2827 author score:0.708123392 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) ensemblbacteria:AAC65257(transcript)|ensemblbacteria:TP_0269(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006467(MiaB-like tRNA modifying enzyme)|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR038135|refseq:WP_010881718.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0269|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:R0+pKSsUrwJUTiyWqcbZFpkqooY243276 intact-crc:E6D02329F1DD5DBA|rigid:E2bT7FhWyTajdOZO2VgYSpMOdKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83887 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587078|imex:IM-9152-2828 author score:0.572895733 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:269C6CBCDBA677B3|rigid:ovcVmw8X67UzbV2HkKAcid8/iR0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83997 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587084|imex:IM-9152-2829 author score:0.445829875 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 intact-crc:FCBA058390D5895A|rigid:AsXVk2mgTR6Keryg7BK6DMqsdIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83282 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587090|imex:IM-9152-2830 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:F8120FA0C3B7A9C7|rigid:hJbJQogdJlZ9fHyKyhtzZ/sORKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83997 uniprotkb:O83958 intact:EBI-1587029|ensemblbacteria:AAC26588|ensemblbacteria:AGN76198 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83997_trepa(display_long)|uniprotkb:TP_1034(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587096|imex:IM-9152-2831 author score:0.001724604 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004837(Sodium/calcium exchanger membrane region)|ensemblbacteria:AAC26588(transcript)|ensemblbacteria:AGN76198(transcript)|ensemblbacteria:TP_1034(gene)|ensemblbacteria:TPANIC_1034(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882478.1|interpro:IPR004481(K+-dependent Na+/Ca+ exchanger related-protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1034; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DWM2aQUzmGGI1DSLlJwTkSY/3+U243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:5D9075211F39B1D5|rigid:9AaB9SPdric5VKs7asDmeMR23dE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:O83329 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587102|imex:IM-9152-2832 author score:0.782235769 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 intact-crc:A9DF1843E6B18732|rigid:gQhUH9rZ5DG43902k8D9dHzodHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83329 uniprotkb:O83411 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587121|imex:IM-9152-2834 author score:0.679436106 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 intact-crc:BD5EEE6FC7662FDF|rigid:siO9Twd4riUwvRRsmeAN6H5Kqag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83329 uniprotkb:O66106 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587115|imex:IM-9152-2833 author score:0.726110141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:85632ACEE7E89AC4|rigid:fW0YgynHPt8TdBLIeMpvGZiUQ3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83329 uniprotkb:O83239 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587127|imex:IM-9152-2835 author score:0.605422711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:D8F7EA3927512CB4|rigid:yywDenmnWpWw6ht3bM8Racr0MXw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83329 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587133|imex:IM-9152-2836 author score:0.566252375 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 intact-crc:5FAA7A5363FF9120|rigid:MKdYIuevTan8fvLO/TpTs6nUOwQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83329 uniprotkb:O83574 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587145|imex:IM-9152-2838 author score:0.206071282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:19390C9A12690C00|rigid:lmeWQ4jyh+TgjGPs4V9T7n3ENIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83329 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1587110|ensemblbacteria:AAC65296|ensemblbacteria:AGN75511 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83329_trepa(display_long)|uniprotkb:TP_0307(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587139|imex:IM-9152-2837 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR005543(PASTA)|refseq:WP_010881756.1|ensemblbacteria:AAC65296(transcript)|ensemblbacteria:AGN75511(transcript)|ensemblbacteria:TP_0307(gene)|ensemblbacteria:TPANIC_0307(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0307; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:URFEmemVEQOk91sg4f0roAd62F8243276 intact-crc:BFDA934F5D1F7549|rigid:VYKDE9WikZbik7zxpM7TeJ+FeEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83883 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1587151|ensemblbacteria:AAC65864 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:y913_trepa(display_long)|uniprotkb:TP_0913(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587154|imex:IM-9152-2839 author score:0.781508376 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR003509(Protein of unknown function UPF0102)|ensemblbacteria:AAC65864(transcript)|ensemblbacteria:TP_0913(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|refseq:WP_010882356.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0913; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:aHxNFCGa8Ur9BjtmfJyHSZVS3gs243276 intact-crc:BAC1838556D5026C|rigid:ccb8FKXjtk5jSbjnO+UyRZmneIc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83883 uniprotkb:O83927 intact:EBI-1587151|ensemblbacteria:AAC65864 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y913_trepa(display_long)|uniprotkb:TP_0913(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587160|imex:IM-9152-2840 author score:0.419620108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR003509(Protein of unknown function UPF0102)|ensemblbacteria:AAC65864(transcript)|ensemblbacteria:TP_0913(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|refseq:WP_010882356.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0913; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aHxNFCGa8Ur9BjtmfJyHSZVS3gs243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:E562A9889C89A164|rigid:RgAMQuk8f8HIZDkCL8Txaxm3lPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83883 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1587151|ensemblbacteria:AAC65864 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y913_trepa(display_long)|uniprotkb:TP_0913(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587166|imex:IM-9152-2841 author score:0.002562106 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR003509(Protein of unknown function UPF0102)|ensemblbacteria:AAC65864(transcript)|ensemblbacteria:TP_0913(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|refseq:WP_010882356.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0913; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:aHxNFCGa8Ur9BjtmfJyHSZVS3gs243276 intact-crc:7BDA206E0A4D0013|rigid:C2C72TAXEcAWKBW+fY6tu3wUAnM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83169 uniprotkb:O52778 intact:EBI-1587172|ensemblbacteria:AAC65124 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 psi-mi:y133_trepa(display_long)|uniprotkb:TP_0133(locus name) psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587175|imex:IM-9152-2842 author score:0.780918179 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65124(transcript)|ensemblbacteria:TP_0133(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0133; PREY protein TP_0640|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KoNv/z5lIHn5Eo3MtWVLJMw9pN0243276 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 intact-crc:06A0C0B9B3375EA6|rigid:rVPp/ERcE0Zuswr/8hoMh+u5sM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83195 uniprotkb:O83169 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 intact:EBI-1587172|ensemblbacteria:AAC65124 psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:y133_trepa(display_long)|uniprotkb:TP_0133(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587181|imex:IM-9152-2843 author score:0.731412401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 ensemblbacteria:AAC65124(transcript)|ensemblbacteria:TP_0133(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0133; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 rogid:KoNv/z5lIHn5Eo3MtWVLJMw9pN0243276 intact-crc:CB0CBAE57B9760D9|rigid:/9YX4LSnnrAUD6Uw1OdZrNd3Nsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83169 uniprotkb:O83804 intact:EBI-1587172|ensemblbacteria:AAC65124 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:y133_trepa(display_long)|uniprotkb:TP_0133(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587187|imex:IM-9152-2844 author score:0.600969391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65124(transcript)|ensemblbacteria:TP_0133(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0133; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KoNv/z5lIHn5Eo3MtWVLJMw9pN0243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:EDC54E19B33BDE57|rigid:tgkR+Ul+tb5sMrjRlEYNkoFZevE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83186 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1587193|ensemblbacteria:AAC65135|ensemblbacteria:AGN75370 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83186_trepa(display_long)|uniprotkb:TP_0151(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587202|imex:IM-9152-2846 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004338(NQR2 and RnfD)|ensemblbacteria:AAC65135(transcript)|ensemblbacteria:AGN75370(transcript)|ensemblbacteria:TP_0151(gene)|ensemblbacteria:TPANIC_0151(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010881598.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0151; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:HJl9UOmIXHk1G4ObelL8d72oXnI243276 intact-crc:92CBB6C743D2B897|rigid:Qw4TjDOsl0ZNyNXPjBDcCGEKvw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83186 uniprotkb:O83664 intact:EBI-1587193|ensemblbacteria:AAC65135|ensemblbacteria:AGN75370 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:o83186_trepa(display_long)|uniprotkb:TP_0151(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587196|imex:IM-9152-2845 author score:0.780918179 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004338(NQR2 and RnfD)|ensemblbacteria:AAC65135(transcript)|ensemblbacteria:AGN75370(transcript)|ensemblbacteria:TP_0151(gene)|ensemblbacteria:TPANIC_0151(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010881598.1 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0151; PREY protein TP_0658|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJl9UOmIXHk1G4ObelL8d72oXnI243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:D6C2536C0853FBED|rigid:OGJpwwnmpslbHJQ12Dkl25Dam7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83247 uniprotkb:O83293 intact:EBI-1587214|ensemblbacteria:AAC65205|ensemblbacteria:AGN75432 intact:EBI-1583512|ensemblbacteria:AAC65257 psi-mi:o83247_trepa(display_long)|uniprotkb:TP_0218(locus name) psi-mi:mtab_trepa(display_long)|uniprotkb:mtaB(gene name)|psi-mi:mtaB(display_short)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0269(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587217|imex:IM-9152-2848 author score:0.779407236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001932(Protein phosphatase 2C-related)|ensemblbacteria:AAC65205(transcript)|ensemblbacteria:AGN75432(transcript)|ensemblbacteria:TP_0218(gene)|ensemblbacteria:TPANIC_0218(gene)|go:"GO:0016791"(phosphatase activity)|refseq:WP_010881666.1|interpro:IPR036457 ensemblbacteria:AAC65257(transcript)|ensemblbacteria:TP_0269(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006467(MiaB-like tRNA modifying enzyme)|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR038135|refseq:WP_010881718.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0218; PREY protein TP_0269|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Y5hdN3OVoicATzBc7H3jNixi3yQ243276 rogid:R0+pKSsUrwJUTiyWqcbZFpkqooY243276 intact-crc:34E5802AFB7A0F46|rigid:Qz0T4Y+uERLgH8xAD8bmIibHeVA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83186 uniprotkb:O83887 intact:EBI-1587193|ensemblbacteria:AAC65135|ensemblbacteria:AGN75370 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83186_trepa(display_long)|uniprotkb:TP_0151(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587208|imex:IM-9152-2847 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004338(NQR2 and RnfD)|ensemblbacteria:AAC65135(transcript)|ensemblbacteria:AGN75370(transcript)|ensemblbacteria:TP_0151(gene)|ensemblbacteria:TPANIC_0151(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010881598.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0151; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJl9UOmIXHk1G4ObelL8d72oXnI243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:7A36B6EBBC77D981|rigid:4rraZLgMM2HyUyep15RPCFlD10A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83247 uniprotkb:O83392 intact:EBI-1587214|ensemblbacteria:AAC65205|ensemblbacteria:AGN75432 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:o83247_trepa(display_long)|uniprotkb:TP_0218(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587223|imex:IM-9152-2849 author score:0.740166777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001932(Protein phosphatase 2C-related)|ensemblbacteria:AAC65205(transcript)|ensemblbacteria:AGN75432(transcript)|ensemblbacteria:TP_0218(gene)|ensemblbacteria:TPANIC_0218(gene)|go:"GO:0016791"(phosphatase activity)|refseq:WP_010881666.1|interpro:IPR036457 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0218; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Y5hdN3OVoicATzBc7H3jNixi3yQ243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:2ABB177E9308C09E|rigid:hf/CGY+g0fpLgTdJbNV9VJqlmM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83247 uniprotkb:O83887 intact:EBI-1587214|ensemblbacteria:AAC65205|ensemblbacteria:AGN75432 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83247_trepa(display_long)|uniprotkb:TP_0218(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587229|imex:IM-9152-2850 author score:0.661840921 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001932(Protein phosphatase 2C-related)|ensemblbacteria:AAC65205(transcript)|ensemblbacteria:AGN75432(transcript)|ensemblbacteria:TP_0218(gene)|ensemblbacteria:TPANIC_0218(gene)|go:"GO:0016791"(phosphatase activity)|refseq:WP_010881666.1|interpro:IPR036457 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0218; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Y5hdN3OVoicATzBc7H3jNixi3yQ243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:E30C9D073C870651|rigid:QeTK4yWOLBDnXd2s5jYy8HZXpkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83419 uniprotkb:O83255 intact:EBI-1587245|ensemblbacteria:AAC65395 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 psi-mi:y404_trepa(display_long)|uniprotkb:TP_0404(locus name) psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587241|imex:IM-9152-2852 author score:0.777888835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65395(transcript)|ensemblbacteria:TP_0404(gene)|refseq:WP_010881852.1|interpro:IPR036866 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0227; PREY protein TP_0404|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0ZEbcm4oQ+3QiuUDeDTvObrQ9yM243276 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 intact-crc:46027D07C2B7A093|rigid:pT9AYVZE+FiwyhEN4IF4gMXcpfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83247 uniprotkb:O83572 intact:EBI-1587214|ensemblbacteria:AAC65205|ensemblbacteria:AGN75432 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83247_trepa(display_long)|uniprotkb:TP_0218(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587235|imex:IM-9152-2851 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001932(Protein phosphatase 2C-related)|ensemblbacteria:AAC65205(transcript)|ensemblbacteria:AGN75432(transcript)|ensemblbacteria:TP_0218(gene)|ensemblbacteria:TPANIC_0218(gene)|go:"GO:0016791"(phosphatase activity)|refseq:WP_010881666.1|interpro:IPR036457 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0218; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Y5hdN3OVoicATzBc7H3jNixi3yQ243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:C2CDEDA321BC7D6A|rigid:lcIHYGfvxHHyPl6KJtwzUo8M1os false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83255 uniprotkb:O83969 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587256|imex:IM-9152-2854 author score:0.433385537 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0227; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:18B42D4AEA09EA02|rigid:Tb6MrBsSwP9WyuQp2QPCdJhJ6DY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83255 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587250|imex:IM-9152-2853 author score:0.717143431 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0227; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 intact-crc:BC6994B09E949F58|rigid:N4IlLxh+dZfCxz41Sq+E/glENT8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83255 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587262|imex:IM-9152-2855 author score:0.193289786 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0227; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 intact-crc:80A08ECBAB42E1A4|rigid:dn3I0UBoAE/4s9cbjZWYJ+I5Ddk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83255 uniprotkb:O83958 intact:EBI-1584616|ensemblbacteria:AAC65214|ensemblbacteria:AGN75440 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83255_trepa(display_long)|uniprotkb:TP_0227(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587268|imex:IM-9152-2856 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65214(transcript)|ensemblbacteria:AGN75440(transcript)|ensemblbacteria:TP_0227(gene)|ensemblbacteria:TPANIC_0227(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881675.1|interpro:IPR027417|interpro:IPR015856(ABC transporter, cobalt import, CbiO) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0227; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zEsvznzBCBlhhezJ7Ynbyix+rQ243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:342A1E20B1D2901A|rigid:gUbHZmIHe0KZakBQwYckc12rTus false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83742 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1587278|ensemblbacteria:AAC65732 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:y761_trepa(display_long)|uniprotkb:TP_0761(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587274|imex:IM-9152-2857 author score:0.777888835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 ensemblbacteria:AAC65732(transcript)|ensemblbacteria:TP_0761(gene)|refseq:WP_010882206.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0341; PREY protein TP_0761|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:2iVnAjV5YAmDmbht1QVYHFya8sg243276 intact-crc:0D1815EEAE8EA1A1|rigid:EEyvq+KhyxIi44PhX0j03Iz9Us8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83312 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587289|imex:IM-9152-2859 author score:0.311588675 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0341; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:B53AF47DCAEDFF33|rigid:Y+rsjanN7Av7RiiaJoEAxO6Oxmg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83361 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587283|imex:IM-9152-2858 author score:0.692644577 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0341; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:B42B842757F139D1|rigid:Q0Hi3X6wrOIrUfahuuGZn+w+CDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83361 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587301|imex:IM-9152-2861 author score:0.003087699 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0341; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:7C870629144D3A69|rigid:Q1XqZIPRMwue5IMG6dfGHHxWU6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83361 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587295|imex:IM-9152-2860 author score:0.292573962 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0341; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:117B4C5F414E53EE|rigid:ExPObgj0M7X3HYH4iD/d+ZWlKII false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83941 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1587314|ensemblbacteria:AAC65940 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587307|imex:IM-9152-2862 author score:0.777888835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0976; PREY protein TP_0876|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 intact-crc:819F9614F1725D66|rigid:kSaoekap/O8PtH9f0ckhdZQq76A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83777 uniprotkb:O83941 intact:EBI-1582789|ensemblbacteria:AAC65768 intact:EBI-1587314|ensemblbacteria:AAC65940 psi-mi:y799_trepa(display_long)|uniprotkb:TP_0799(locus name) psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587325|imex:IM-9152-2864 author score:0.773202451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65768(transcript)|ensemblbacteria:TP_0799(gene) ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0976; PREY protein TP_0799|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jY5xnPna4k8h37+WC4al4IEHqTQ243276 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 intact-crc:FFACD1DA4D67FD46|rigid:JwocknBX60W85yzdpBds98X824I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83447 uniprotkb:O83941 intact:EBI-1585025|ensemblbacteria:AAC65420 intact:EBI-1587314|ensemblbacteria:AAC65940 psi-mi:y432_trepa(display_long)|uniprotkb:TP_0432(locus name) psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587319|imex:IM-9152-2863 author score:0.773202451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65420(transcript)|ensemblbacteria:TP_0432(gene)|refseq:WP_010881880.1 ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0976; PREY protein TP_0432|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:C9WqS8T1hASpueWfFwanX4vNYXE243276 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 intact-crc:E1E00205A3681CE3|rigid:ZM8SKS3oFZYxFOQMBqcpuBgf6IU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83261 uniprotkb:O83932 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 intact:EBI-1587347|ensemblbacteria:AAC65924 psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:y966_trepa(display_long)|uniprotkb:TP_0966(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587343|imex:IM-9152-2867 author score:0.777888835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 ensemblbacteria:AAC65924(transcript)|ensemblbacteria:TP_0966(gene)|refseq:WP_010882410.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0233; PREY protein TP_0966|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 rogid:H5jKNl5bFmPC5m+gwSHyZKnM5os243276 intact-crc:A5B626E23143F5AA|rigid:rSwsja9ZeStBxp5U1IVJ4HkZHnI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83941 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1587314|ensemblbacteria:AAC65940 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587337|imex:IM-9152-2866 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0976; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 intact-crc:E06CBB28CE0432EF|rigid:gAYlqkINNB87Lqm8Mx+vm4FlH4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83941 uniprotkb:O83699 intact:EBI-1587314|ensemblbacteria:AAC65940 intact:EBI-1586728|ensemblbacteria:AAC65670 psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:rpoz_trepa(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:TP_0701(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587331|imex:IM-9152-2865 author score:0.768446622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 interpro:IPR006110(RNA polymerase Rpb6)|ensemblbacteria:AAC65670(transcript)|ensemblbacteria:TP_0701(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|refseq:WP_010882146.1|interpro:IPR036161 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0976; PREY protein TP_0701|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 rogid:qImQ7fWBJEGqpSutHzSZ0CANeg0243276 intact-crc:37488219C3E3DEE0|rigid:oU2LQCU4tZ+eFACz9raDjEnR1UQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83968 uniprotkb:O83261 intact:EBI-1587352|ensemblbacteria:AAC65959 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y1003_trepa(display_long)|uniprotkb:TP_1003(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587355|imex:IM-9152-2868 author score:0.777888835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65959(transcript)|ensemblbacteria:TP_1003(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882447.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0233; PREY protein TP_1003|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2/1EhItIlJfPaRhQ9hlikXrL08E243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:C95AC404E47A73B6|rigid:alWTzf+yq/jq3+mtIPSRKHJaEEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83261 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587361|imex:IM-9152-2869 author score:0.130985061 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0233; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:759F2F9824D5163B|rigid:SSZbjHmOBlL0GdEdrc5NdAWZGWc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83126 uniprotkb:O83126 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587379|imex:IM-9152-2872 author score:0.7778036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0088; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:028240E6FC248E6B|rigid:KjWCqsrbOx8UXIKESG/7zxWYuxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83261 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587373|imex:IM-9152-2871 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0233; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:D6FDE811807A3BC4|rigid:fFvZnR/66jwOvt7Nh8lAFyQBMFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83261 uniprotkb:O83282 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587367|imex:IM-9152-2870 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0233; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:B3CFC0860E75F3D6|rigid:v1l2IZ8gsCJoGgP2w09veXrRnUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83844 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1587391|ensemblbacteria:AAC65837|ensemblbacteria:AGN76043 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:o83844_trepa(display_long)|uniprotkb:TP_0874(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587394|imex:IM-9152-2874 author score:0.7778036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65837(transcript)|ensemblbacteria:AGN76043(transcript)|ensemblbacteria:TP_0874(gene)|ensemblbacteria:TPANIC_0874(gene)|refseq:WP_010882317.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0874; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:DAvZ07QDH2IUmDCpEj1Gx1SGfCY243276 intact-crc:0E40FFB8DEC3C15E|rigid:6Yoi7O1w2yByETRBesxbqtwpiP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83126 uniprotkb:O83804 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587385|imex:IM-9152-2873 author score:0.615895006 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0088; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:694DC9246D73231B|rigid:d/7fFrLtwM7/lFL0uZDuZvtcNeY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O66104 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1586629|uniprotkb:Q7DFN4 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:o66104_trepl(display_long)|uniprotkb:FA889_04855(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587406|imex:IM-9152-2876 author score:0.7778036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR001374(Single-stranded nucleic acid binding R3H)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR038247|interpro:IPR032782|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR034079|interpro:IPR038008|interpro:IPR036867|interpro:IPR039247|refseq:WP_010882391.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0948; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:403vszGOWhHQH0wU8zA4Gq26Hto160 intact-crc:8A80F5958B056B0D|rigid:7sf9uJdfRI3juTbSovQk/4TlHuM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83844 uniprotkb:O83958 intact:EBI-1587391|ensemblbacteria:AAC65837|ensemblbacteria:AGN76043 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83844_trepa(display_long)|uniprotkb:TP_0874(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587400|imex:IM-9152-2875 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65837(transcript)|ensemblbacteria:AGN76043(transcript)|ensemblbacteria:TP_0874(gene)|ensemblbacteria:TPANIC_0874(gene)|refseq:WP_010882317.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0874; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DAvZ07QDH2IUmDCpEj1Gx1SGfCY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9374A238DAC5A869|rigid:gQdYzS6vcT/IHe5TzqtlGDE+VRE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83106 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587418|imex:IM-9152-2878 author score:0.77412081 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:A872CC40FCF4D9B3|rigid:igJub1WH7CM0jszpkfibiRMLzdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O66104 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1586629|uniprotkb:Q7DFN4 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o66104_trepl(display_long)|uniprotkb:FA889_04855(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587412|imex:IM-9152-2877 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001374(Single-stranded nucleic acid binding R3H)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR038247|interpro:IPR032782|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR034079|interpro:IPR038008|interpro:IPR036867|interpro:IPR039247|refseq:WP_010882391.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0948; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:403vszGOWhHQH0wU8zA4Gq26Hto160 intact-crc:0E36E30FFB0DD904|rigid:+ixghElOq94oUY94sqkGk0wZbYo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83570 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587430|imex:IM-9152-2880 author score:0.657389745 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:676F898EDB1CBAC7|rigid:immoS/biUUw/M+dWEKVYvv0ZrIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83106 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587424|imex:IM-9152-2879 author score:0.714838962 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:D8A5FB80FF475656|rigid:WiXlLJaiur79EHIIaUWCk6lkRss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83970 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587442|imex:IM-9152-2882 author score:0.565209707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:1788A86693B1ED3B|rigid:aMDWNf9jpWBCGeNoWSv+1kDLUAw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83106 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587436|imex:IM-9152-2881 author score:0.651552908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:0E2E1552887AD5AF|rigid:NLyOD+V+gLYWJsJxtCGB5ZxH9Kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83927 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587448|imex:IM-9152-2883 author score:0.288207686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:4F4D7C5C41285D6C|rigid:ove31xBRrs5mlOmg1uFCOuUOiBY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83106 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587460|imex:IM-9152-2885 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:C3DD7C2A73E2A5AC|rigid:feW3nZ8p2Qdc24FTPtheMG8g/nI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83312 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587454|imex:IM-9152-2884 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:5C9BD40CCA702564|rigid:ndBCjph++jV0wIVDaGPO+5FUIxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83550 uniprotkb:P96130 intact:EBI-1587472|ensemblbacteria:AAC65530 intact:EBI-1583291|ensemblbacteria:AAC65656 psi-mi:y539_trepa(display_long)|uniprotkb:TP_0539(locus name) psi-mi:recg_trepa(display_long)|uniprotkb:recG(gene name)|psi-mi:recG(display_short)|uniprotkb:TP_0687(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587475|imex:IM-9152-2887 author score:0.773202451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881986.1|ensemblbacteria:AAC65530(transcript)|ensemblbacteria:TP_0539(gene) interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR004609(DNA helicase, ATP-dependent, RecG)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR033454|ensemblbacteria:AAC65656(transcript)|ensemblbacteria:TP_0687(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027417|refseq:WP_010882132.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0539; PREY protein TP_0687|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:okjws74g8bV/AwRg/WGXDJ1tWd4243276 rogid:QdgShP2vokjN3ZEytcn1OFR+oR0243276 intact-crc:9F43D294F514DD9F|rigid:pyL4EM1YiisbWHWxasyj6txeOCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83958 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587466|imex:IM-9152-2886 author score:0.001801329 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0067; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:46E7153F0581C07E|rigid:2yCf7TRGWCL1WDSSy4s3rgsRRUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83550 uniprotkb:O83413 intact:EBI-1587472|ensemblbacteria:AAC65530 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y539_trepa(display_long)|uniprotkb:TP_0539(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587487|imex:IM-9152-2889 author score:0.143215719 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881986.1|ensemblbacteria:AAC65530(transcript)|ensemblbacteria:TP_0539(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0539; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:okjws74g8bV/AwRg/WGXDJ1tWd4243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6E0B0262286D89E5|rigid:y2DBwAkYtbMqCNU8xsAmGI+516Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83550 uniprotkb:O83412 intact:EBI-1587472|ensemblbacteria:AAC65530 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:y539_trepa(display_long)|uniprotkb:TP_0539(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587481|imex:IM-9152-2888 author score:0.647316935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881986.1|ensemblbacteria:AAC65530(transcript)|ensemblbacteria:TP_0539(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0539; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:okjws74g8bV/AwRg/WGXDJ1tWd4243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:4C5EDE6FBD1C25DA|rigid:1SEwGdrsPSkBW6oNrxk7r4Vuay8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83550 uniprotkb:O83954 intact:EBI-1587472|ensemblbacteria:AAC65530 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y539_trepa(display_long)|uniprotkb:TP_0539(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587499|imex:IM-9152-2891 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881986.1|ensemblbacteria:AAC65530(transcript)|ensemblbacteria:TP_0539(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0539; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:okjws74g8bV/AwRg/WGXDJ1tWd4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1AFE3E5F414C246B|rigid:e+GGH1hKEAsB8TWD+XnSlShMXgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83550 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1587472|ensemblbacteria:AAC65530 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y539_trepa(display_long)|uniprotkb:TP_0539(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587493|imex:IM-9152-2890 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010881986.1|ensemblbacteria:AAC65530(transcript)|ensemblbacteria:TP_0539(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0539; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:okjws74g8bV/AwRg/WGXDJ1tWd4243276 intact-crc:EF6A229DD1AEB323|rigid:1EBajWg+kqftY5nxCtHrmAXvUgw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23033 uniprotkb:O83195 intact:EBI-1198190|uniprotkb:O83073|intact:EBI-1587508|ensemblbacteria:AAC65026 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:ch60_trepa(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:Common antigen(gene name synonym)|uniprotkb:TP4 antigen(gene name synonym)|uniprotkb:TPN60(gene name synonym)|uniprotkb:Tp4(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:TP_0030(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587518|imex:IM-9152-2893 author score:0.771958899 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_010881479.1|interpro:IPR027410|ensemblbacteria:AAC65026(transcript)|ensemblbacteria:TP_0030(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0030; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NC5w2Hh31+P3ygvXfMF71bML3Yc243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:35E809EB74EF0EA7|rigid:SC8D9xtkRzV0ymf4NgvxX92RjYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23033 uniprotkb:O83952 intact:EBI-1198190|uniprotkb:O83073|intact:EBI-1587508|ensemblbacteria:AAC65026 intact:EBI-1587505|ensemblbacteria:AAC65950 psi-mi:ch60_trepa(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:Common antigen(gene name synonym)|uniprotkb:TP4 antigen(gene name synonym)|uniprotkb:TPN60(gene name synonym)|uniprotkb:Tp4(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:TP_0030(locus name) psi-mi:y987_trepa(display_long)|uniprotkb:TP_0987(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587512|imex:IM-9152-2892 author score:0.773202451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_010881479.1|interpro:IPR027410|ensemblbacteria:AAC65026(transcript)|ensemblbacteria:TP_0030(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding) ensemblbacteria:AAC65950(transcript)|ensemblbacteria:TP_0987(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0030; PREY protein TP_0987|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NC5w2Hh31+P3ygvXfMF71bML3Yc243276 rogid:XPQPEHLaISB8DFhui/DyfCu12dQ243276 intact-crc:A87348F7C803116B|rigid:TNfvqjzl5MMfpe//AvbST/VVdVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23033 uniprotkb:O83089 intact:EBI-1198190|uniprotkb:O83073|intact:EBI-1587508|ensemblbacteria:AAC65026 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:ch60_trepa(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:Common antigen(gene name synonym)|uniprotkb:TP4 antigen(gene name synonym)|uniprotkb:TPN60(gene name synonym)|uniprotkb:Tp4(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:TP_0030(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587530|imex:IM-9152-2895 author score:0.73323602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_010881479.1|interpro:IPR027410|ensemblbacteria:AAC65026(transcript)|ensemblbacteria:TP_0030(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0030; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NC5w2Hh31+P3ygvXfMF71bML3Yc243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:E52226D5A17130C1|rigid:SG+DqTorcosNHvcJGSmvu0zrvsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23033 uniprotkb:O07885 intact:EBI-1198190|uniprotkb:O83073|intact:EBI-1587508|ensemblbacteria:AAC65026 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 psi-mi:ch60_trepa(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:Common antigen(gene name synonym)|uniprotkb:TP4 antigen(gene name synonym)|uniprotkb:TPN60(gene name synonym)|uniprotkb:Tp4(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:TP_0030(locus name) psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587524|imex:IM-9152-2894 author score:0.748733837 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_010881479.1|interpro:IPR027410|ensemblbacteria:AAC65026(transcript)|ensemblbacteria:TP_0030(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0030; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NC5w2Hh31+P3ygvXfMF71bML3Yc243276 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 intact-crc:0D1217E824BE5C87|rigid:AsCGDH5DTFAmHg3iv7vLCCgJs+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83674 uniprotkb:O83732 intact:EBI-1587546|ensemblbacteria:AAC26566|ensemblbacteria:AGN75846 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 psi-mi:o83674_trepa(display_long)|uniprotkb:TP_0668(locus name) psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587542|imex:IM-9152-2897 author score:0.771566929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003425(Protein of unknown function YGGT)|ensemblbacteria:AAC26566(transcript)|ensemblbacteria:AGN75846(transcript)|ensemblbacteria:TP_0668(gene)|ensemblbacteria:TPANIC_0668(gene)|go:"GO:0016020"(membrane)|refseq:WP_010882113.1 rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0668; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VVYfvUkGjB4PvfANjBECWub568M243276 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 intact-crc:C12B97D1CAC57E7D|rigid:gcVPGXQIL94+6g1sYfV9Sa5tC2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:P23033 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198190|uniprotkb:O83073|intact:EBI-1587508|ensemblbacteria:AAC65026 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:ch60_trepa(display_long)|uniprotkb:groEL(gene name)|psi-mi:groEL(display_short)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-60(gene name synonym)|uniprotkb:Common antigen(gene name synonym)|uniprotkb:TP4 antigen(gene name synonym)|uniprotkb:TPN60(gene name synonym)|uniprotkb:Tp4(gene name synonym)|uniprotkb:groL(gene name synonym)|uniprotkb:mopA(gene name synonym)|uniprotkb:TP_0030(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587536|imex:IM-9152-2896 author score:0.683261482 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|refseq:WP_010881479.1|interpro:IPR027410|ensemblbacteria:AAC65026(transcript)|ensemblbacteria:TP_0030(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0030; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:NC5w2Hh31+P3ygvXfMF71bML3Yc243276 intact-crc:13E545103FF979AA|rigid:tF38J3s0eLzT9Ng8tl+VnKDOB2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83674 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1587546|ensemblbacteria:AAC26566|ensemblbacteria:AGN75846 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83674_trepa(display_long)|uniprotkb:TP_0668(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587557|imex:IM-9152-2899 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR003425(Protein of unknown function YGGT)|ensemblbacteria:AAC26566(transcript)|ensemblbacteria:AGN75846(transcript)|ensemblbacteria:TP_0668(gene)|ensemblbacteria:TPANIC_0668(gene)|go:"GO:0016020"(membrane)|refseq:WP_010882113.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0668; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:VVYfvUkGjB4PvfANjBECWub568M243276 intact-crc:0F64F0E6955FB819|rigid:zTo4sP8bBlKZRDqLGDZNRjpauC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83674 uniprotkb:O83572 intact:EBI-1587546|ensemblbacteria:AAC26566|ensemblbacteria:AGN75846 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83674_trepa(display_long)|uniprotkb:TP_0668(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587551|imex:IM-9152-2898 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003425(Protein of unknown function YGGT)|ensemblbacteria:AAC26566(transcript)|ensemblbacteria:AGN75846(transcript)|ensemblbacteria:TP_0668(gene)|ensemblbacteria:TPANIC_0668(gene)|go:"GO:0016020"(membrane)|refseq:WP_010882113.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0668; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VVYfvUkGjB4PvfANjBECWub568M243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:F1D6EF9C74CCB3AE|rigid:rJyN8VFIerBB7tltBLAOfgfbKDs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07888 uniprotkb:O83572 intact:EBI-1198788|intact:EBI-1587567|ensemblbacteria:AAC65688 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:flil_trepa(display_long)|uniprotkb:fliL(gene name)|psi-mi:fliL(display_short)|uniprotkb:TP_0722(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587573|imex:IM-9152-2901 author score:0.640055825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005503(Flagellar basal body-associated protein FliL)|refseq:WP_010882167.1|ensemblbacteria:AAC65688(transcript)|ensemblbacteria:TP_0722(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0722; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HxvxKeQjj2icqHEZ+jCsvgSOC3E243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:09137441511DD289|rigid:Bhe4cT3CjoUcTBt7vvaycrpP7n0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83284 uniprotkb:O07888 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 intact:EBI-1198788|intact:EBI-1587567|ensemblbacteria:AAC65688 psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:flil_trepa(display_long)|uniprotkb:fliL(gene name)|psi-mi:fliL(display_short)|uniprotkb:TP_0722(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587563|imex:IM-9152-2900 author score:0.770010486 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005503(Flagellar basal body-associated protein FliL)|refseq:WP_010882167.1|ensemblbacteria:AAC65688(transcript)|ensemblbacteria:TP_0722(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0722; PREY protein TP_0260|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 rogid:HxvxKeQjj2icqHEZ+jCsvgSOC3E243276 intact-crc:1FF92496D05E0D03|rigid:Hxx7ete4Xj6B8YT6AcjmIM+C7yA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O07888 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198788|intact:EBI-1587567|ensemblbacteria:AAC65688 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:flil_trepa(display_long)|uniprotkb:fliL(gene name)|psi-mi:fliL(display_short)|uniprotkb:TP_0722(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587579|imex:IM-9152-2902 author score:0.585853792 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR005503(Flagellar basal body-associated protein FliL)|refseq:WP_010882167.1|ensemblbacteria:AAC65688(transcript)|ensemblbacteria:TP_0722(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0722; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:HxvxKeQjj2icqHEZ+jCsvgSOC3E243276 intact-crc:27BFDAD707F3BC17|rigid:aShtTKxADg0v4A1DiFQMTYH7NIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O07888 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198788|intact:EBI-1587567|ensemblbacteria:AAC65688 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:flil_trepa(display_long)|uniprotkb:fliL(gene name)|psi-mi:fliL(display_short)|uniprotkb:TP_0722(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587585|imex:IM-9152-2903 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005503(Flagellar basal body-associated protein FliL)|refseq:WP_010882167.1|ensemblbacteria:AAC65688(transcript)|ensemblbacteria:TP_0722(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0722; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:HxvxKeQjj2icqHEZ+jCsvgSOC3E243276 intact-crc:F55BF40C76930F8E|rigid:WvizZjnXUxvk/svkzWgPLS7yS7I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83770 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1587591|ensemblbacteria:AAC65765 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y791_trepa(display_long)|uniprotkb:TP_0791(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587606|imex:IM-9152-2906 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65765(transcript)|ensemblbacteria:TP_0791(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0791; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:MqyFxNyuSX/bJ0jVVZXb0fEnXPM243276 intact-crc:C6F2FD0635B4E87A|rigid:S5+dOgwu97+mndF8zQYG311jQ4g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83770 uniprotkb:O83305 intact:EBI-1587591|ensemblbacteria:AAC65765 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y791_trepa(display_long)|uniprotkb:TP_0791(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587600|imex:IM-9152-2905 author score:0.406113471 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65765(transcript)|ensemblbacteria:TP_0791(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0791; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MqyFxNyuSX/bJ0jVVZXb0fEnXPM243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:3B6540B29CCB03EA|rigid:gnffbZAXheWYJefvj9wDeRIOUa8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83770 uniprotkb:O83960 intact:EBI-1587591|ensemblbacteria:AAC65765 intact:EBI-1583870|ensemblbacteria:AAC26583 psi-mi:y791_trepa(display_long)|uniprotkb:TP_0791(locus name) psi-mi:o83960_trepa(display_long)|uniprotkb:TP_0995(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587594|imex:IM-9152-2904 author score:0.770010486 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65765(transcript)|ensemblbacteria:TP_0791(gene) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC26583(transcript)|ensemblbacteria:TP_0995(gene)|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0791; PREY protein TP_0995|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MqyFxNyuSX/bJ0jVVZXb0fEnXPM243276 rogid:e/7IeUNCDYEoLFDH9to3t6L3g3E243276 intact-crc:9D5AFC94978798C9|rigid:7uTdej69y8CI74eucc+oXzjPKZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83189 uniprotkb:O83981 intact:EBI-1587618|ensemblbacteria:AAC65144 intact:EBI-1587625|ensemblbacteria:AAC65967 psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587621|imex:IM-9152-2908 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_0154|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 intact-crc:A08E740D6117F6FF|rigid:B9feN1O66P0WU9aogZh3ot3yd0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83770 uniprotkb:O83282 intact:EBI-1587591|ensemblbacteria:AAC65765 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y791_trepa(display_long)|uniprotkb:TP_0791(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587612|imex:IM-9152-2907 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65765(transcript)|ensemblbacteria:TP_0791(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0791; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MqyFxNyuSX/bJ0jVVZXb0fEnXPM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:EAD262718660915B|rigid:I8TNH56zLLZzvwlnrsFc2MyRmdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83519 uniprotkb:O83981 intact:EBI-1582119|ensemblbacteria:AAC65494 intact:EBI-1587625|ensemblbacteria:AAC65967 psi-mi:tig_trepa(display_long)|uniprotkb:PPIase(gene name synonym)|uniprotkb:TP_0506(locus name)|uniprotkb:tig(gene name)|psi-mi:tig(display_short) psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587639|imex:IM-9152-2910 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027304|interpro:IPR005215(Trigger factor)|interpro:IPR008880(Trigger factor, C-terminal, bacterial)|interpro:IPR008881(Trigger factor, ribosome-binding, bacterial)|ensemblbacteria:AAC65494(transcript)|ensemblbacteria:TP_0506(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0051301"(cell division)|refseq:WP_010881955.1|interpro:IPR036611|interpro:IPR037041 interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_0506|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:woVkgqeQdmN/cNT5tUTecpn4gUs243276 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 intact-crc:3215BA49854BC92D|rigid:3lneCzgQjoYZR3UvbZk892Ek86E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83981 uniprotkb:O83437 intact:EBI-1587625|ensemblbacteria:AAC65967 intact:EBI-1587634|ensemblbacteria:AAC65418 psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:y422_trepa(display_long)|uniprotkb:TP_0422(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587630|imex:IM-9152-2909 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 ensemblbacteria:AAC65418(transcript)|ensemblbacteria:TP_0422(gene)|refseq:WP_010881870.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_0422|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 rogid:PdgdLhnI4qtapFyv9vDMuZTycKQ243276 intact-crc:02CFD19E99F40E2E|rigid:12QaiwXNRNjtPsRBOEtCh3O44JI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83981 uniprotkb:O83700 intact:EBI-1587625|ensemblbacteria:AAC65967 intact:EBI-1198870|intact:EBI-1583519|ensemblbacteria:AAC65671 psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:o83700_trepa(display_long)|uniprotkb:TP_0702(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587654|imex:IM-9152-2912 author score:0.762027671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|ensemblbacteria:AAC65671(transcript)|ensemblbacteria:TP_0702(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_0702|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 rogid:m+L0PIYpz1pXrbGDyvQbpbjJ9S4243276 intact-crc:8C203368C28CE2A5|rigid:PZH+sqdCbO633rLvYbhkMejB1jI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83981 uniprotkb:O83922 intact:EBI-1587625|ensemblbacteria:AAC65967 intact:EBI-1587649|ensemblbacteria:AAC65922 psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:y956_trepa(display_long)|uniprotkb:TP_0956(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587645|imex:IM-9152-2911 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 interpro:IPR031823|refseq:WP_010882400.1|ensemblbacteria:AAC65922(transcript)|ensemblbacteria:TP_0956(gene)|rcsb pdb:3U64|rcsb pdb:4DI3|rcsb pdb:4DI4|interpro:IPR038537 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_0956|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 rogid:NALMbkkfnIBkTf88VZuBrTQwseM243276 intact-crc:C1BF5A72F54DC28A|rigid:m3Ru2TckpnLD9/HaZvkmf8Nr1dA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83509 uniprotkb:O83505 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587669|imex:IM-9152-2914 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_0492|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:E3396D7E6D119A96|rigid:3VqqrCEjJoTvXNa1FPubbPjdDao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O84002 uniprotkb:O83981 intact:EBI-1585598|ensemblbacteria:AAC26594|ensemblbacteria:AGN76204 intact:EBI-1587625|ensemblbacteria:AAC65967 psi-mi:o84002_trepa(display_long)|uniprotkb:TP_1040(locus name) psi-mi:rny_trepa(display_long)|uniprotkb:TP_1018(locus name)|uniprotkb:rny(gene name)|psi-mi:rny(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587660|imex:IM-9152-2913 author score:0.762027671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|ensemblbacteria:AAC26594(transcript)|ensemblbacteria:AGN76204(transcript)|ensemblbacteria:TP_1040(gene)|ensemblbacteria:TPANIC_1040(gene)|go:"GO:0004812"(aminoacyl-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|refseq:WP_010882484.1 interpro:IPR017705(Conserved hypothetical protein CHP03319, YmdA/YtgF)|interpro:IPR022711|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65967(transcript)|ensemblbacteria:TP_1018(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882462.1|interpro:IPR036612 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1018; PREY protein TP_1040|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00ZukC7RwwIoMwvK60Mt/eBtcgo243276 rogid:5EJHqwB4rVbCoTGzIj7S0LwPY4w243276 intact-crc:4BB5912BB96784A1|rigid:pryZnxvj3IIrGGX5hx04a4Oeq4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83879 uniprotkb:O83509 intact:EBI-1587693|ensemblbacteria:AAC65861 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 psi-mi:rl19_trepa(display_long)|uniprotkb:rplS(gene name)|psi-mi:rplS(display_short)|uniprotkb:TP_0909(locus name) psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587689|imex:IM-9152-2916 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001857(Ribosomal protein L19)|interpro:IPR018257|interpro:IPR008991(Translation protein SH3-like)|ensemblbacteria:AAC65861(transcript)|ensemblbacteria:TP_0909(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882352.1|interpro:IPR038657 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_0909|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9du6UVWUJ5W1+DJGutXUAQCgWs243276 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 intact-crc:AE5EC997779D9C7F|rigid:Rkw/SJFD4seVn88HdhtcEdKAoHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83509 uniprotkb:O83859 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 intact:EBI-1587679|ensemblbacteria:AAC26579 psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:trub_trepa(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:TP_0889(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587683|imex:IM-9152-2915 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR020103|interpro:IPR014780(tRNA pseudouridine synthase B, N-terminal, bacterial-type)|interpro:IPR032819|refseq:WP_010882332.1|ensemblbacteria:AAC26579(transcript)|ensemblbacteria:TP_0889(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_0889|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 rogid:o5ftww0DYll4DHm7NLmtnvvXdcE243276 intact-crc:5B4D26099EFC74F9|rigid:koqKQdenLwdXLZ9AxzgDPD5Lxv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83950 uniprotkb:O83509 intact:EBI-1583714|ensemblbacteria:AAC65942 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 psi-mi:sydnd_trepa(display_long)|uniprotkb:aspS(gene name)|psi-mi:aspS(display_short)|uniprotkb:Non-discriminating aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0985(locus name)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym) psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587709|imex:IM-9152-2918 author score:0.762027671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|ensemblbacteria:AAC65942(transcript)|ensemblbacteria:TP_0985(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|interpro:IPR029351 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_0985|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hJBqLaanJwFwufTRZyDt8fxxWdU243276 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 intact-crc:F22003BA636A0314|rigid:PbC7qU8s4cTZHfkvs5iCLCXo6as false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83509 uniprotkb:O83938 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 intact:EBI-1587703|ensemblbacteria:AAC65930 psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:syfa_trepa(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:TP_0973(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587699|imex:IM-9152-2917 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR022917|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|ensemblbacteria:AAC65930(transcript)|ensemblbacteria:TP_0973(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|refseq:WP_010882417.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_0973|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 rogid:NjlMzGYSGr173q4R8gEEajJDdTI243276 intact-crc:683DD775505EB662|rigid:HXFTYurnqs2uBnf1T+pMnn26A00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83972 uniprotkb:O83509 intact:EBI-1587715|ensemblbacteria:AAC65956 intact:EBI-1587666|ensemblbacteria:AAC65483|ensemblbacteria:AGN75686 psi-mi:rir1_trepa(display_long)|uniprotkb:nrdA(gene name)|psi-mi:nrdA(display_short)|uniprotkb:Ribonucleotide reductase(gene name synonym)|uniprotkb:TP_1008(locus name) psi-mi:o83509_trepa(display_long)|uniprotkb:TP_0496(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587719|imex:IM-9152-2919 author score:0.762027671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039718|interpro:IPR005144(ATP-cone)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|ensemblbacteria:AAC65956(transcript)|ensemblbacteria:TP_1008(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|refseq:WP_010882452.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65483(transcript)|ensemblbacteria:AGN75686(transcript)|ensemblbacteria:TP_0496(gene)|ensemblbacteria:TPANIC_0496(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0496; PREY protein TP_1008|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6N1DBDuvOW96+g2vP5P4UxqeXFY243276 rogid:+gQYp32qqUeOgf0ovCCvEIvzcfs243276 intact-crc:BE531E20FEE36A24|rigid:qG1rpewMSHbYoUWvXFQce0Wqdl0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83664 uniprotkb:O83718 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 intact:EBI-1587734|ensemblbacteria:AAC65704 psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:o83718_trepa(display_long)|uniprotkb:TP_0736(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587737|imex:IM-9152-2921 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR012165(Cytochrome-c3 hydrogenase, gamma subunit)|interpro:IPR019480|interpro:IPR017927|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR017938|ensemblbacteria:AAC65704(transcript)|ensemblbacteria:TP_0736(gene)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR039261 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0736|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 rogid:THvOdZhnA+tzeXnN3s6nz+VoukA243276 intact-crc:B3C2B7B20A4182A0|rigid:FDvZ2ne2P40eUigARD81FcO3liQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83664 uniprotkb:O83629 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 intact:EBI-1587725|ensemblbacteria:AAC65594 psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:o83629_trepa(display_long)|uniprotkb:TP_0620(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587728|imex:IM-9152-2920 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65594(transcript)|ensemblbacteria:TP_0620(gene)|refseq:WP_010882066.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0620|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 rogid:1yM1Td4oxZbVGw3g3E+6BkcppBE243276 intact-crc:AE0DD91EC02A7C27|rigid:YtU6a2+07GtNjlFOlrDzfTrmRik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83664 uniprotkb:O83803 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 intact:EBI-1587743|ensemblbacteria:AAC65797 psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:syr_trepa(display_long)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0831(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587747|imex:IM-9152-2922 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65797(transcript)|ensemblbacteria:TP_0831(gene)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|refseq:WP_010882275.1|interpro:IPR035684|interpro:IPR036695 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0831|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 rogid:aln69UFLKLBAAUJHdtg7+v6YzXE243276 intact-crc:A05D87805E250663|rigid:Lb6qwK4xXdX2qFgnW69ojxMB0so false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83664 uniprotkb:O83909 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587762|imex:IM-9152-2924 author score:0.709839301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:CFDCF9C963B6CFB6|rigid:y4l2lOj7itEE18L8NSKBJTvhF6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83664 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587753|imex:IM-9152-2923 author score:0.766875342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0941|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:790F16388E89C93F|rigid:UeKsKjlNAE8oPAXuNlkKVB1AzNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83063 uniprotkb:O83275 intact:EBI-1587774|ensemblbacteria:AAC65015 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587778|imex:IM-9152-2926 author score:0.766816943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:10FE16A6683EF687|rigid:4Qxr4TNB4xz3FBQxTDn8iOp4g5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83664 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587768|imex:IM-9152-2925 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0658; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:64C537BCBAF5082E|rigid:UE2RYk5WmgzGhJ2QAMj4eYzy7GI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83063 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587790|imex:IM-9152-2928 author score:0.400022648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:51BE24B418D225F1|rigid:pPjdtS/9Chvt4UFbYDxfqemubGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83063 uniprotkb:O83723 intact:EBI-1587774|ensemblbacteria:AAC65015 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587784|imex:IM-9152-2927 author score:0.759093962 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:469F88E54D61BED6|rigid:mTVAZ2dCax+kK8JYK0CtTO4ka5c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83063 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587802|imex:IM-9152-2930 author score:0.239669879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:37F65EC1DE0F81DC|rigid:c92Ka2JVc4eLH9HA3S/dkW2VcZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83063 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587796|imex:IM-9152-2929 author score:0.333292903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:9EC54AFF778F6E42|rigid:I99ASlfgI34ty9BnNvtyaWp8S7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83063 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587814|imex:IM-9152-2932 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:68D54A45B6D6A730|rigid:lsT0RcNclB6nhjakf4laReJ08+4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83063 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587808|imex:IM-9152-2931 author score:0.186323126 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:CD8028E44C5819FF|rigid:sP/+D8aWIQFftaKrbHkhkAJfSLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83063 uniprotkb:O83958 intact:EBI-1587774|ensemblbacteria:AAC65015 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587826|imex:IM-9152-2934 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:836DF8CEB7A2FCD3|rigid:exGoTKe0kL7qcdE9C0ZlquQOiVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83063 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1587774|ensemblbacteria:AAC65015 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:grea_trepa(display_long)|uniprotkb:greA(gene name)|psi-mi:greA(display_short)|uniprotkb:Transcript cleavage factor GreA(gene name synonym)|uniprotkb:TP_0019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587820|imex:IM-9152-2933 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR028624|interpro:IPR018151|interpro:IPR006359(Prokaryotic transcription elongation factor GreA)|interpro:IPR023459|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR022691|ensemblbacteria:AAC65015(transcript)|ensemblbacteria:TP_0019(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR036805|interpro:IPR036953 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0019; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:6/VCxoDNpe3KrBKAbOM026vjaOY243276 intact-crc:E0AE61579A458F80|rigid:DKlF1c2aCq6+3ne0tiEseutUHmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83995 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1587832|ensemblbacteria:AAC65984 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:y1032_trepa(display_long)|uniprotkb:TP_1032(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587841|imex:IM-9152-2936 author score:0.694797727 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR024045|ensemblbacteria:AAC65984(transcript)|ensemblbacteria:TP_1032(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882476.1|interpro:IPR038690 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1032; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:KPVDDwL31T8wdXtIKPpci4UQ19g243276 intact-crc:511A2715CB2372C4|rigid:cHAe24o46UGqRAIM0CmF6vqnvYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83995 uniprotkb:O83773 intact:EBI-1587832|ensemblbacteria:AAC65984 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:y1032_trepa(display_long)|uniprotkb:TP_1032(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587835|imex:IM-9152-2935 author score:0.763621552 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024045|ensemblbacteria:AAC65984(transcript)|ensemblbacteria:TP_1032(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882476.1|interpro:IPR038690 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1032; PREY protein TP_0795|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KPVDDwL31T8wdXtIKPpci4UQ19g243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:0BDE8280B01FA193|rigid:ocYsEqIoCfzHIP+vLA1bqosun4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83995 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1587832|ensemblbacteria:AAC65984 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y1032_trepa(display_long)|uniprotkb:TP_1032(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587853|imex:IM-9152-2938 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR024045|ensemblbacteria:AAC65984(transcript)|ensemblbacteria:TP_1032(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882476.1|interpro:IPR038690 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1032; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:KPVDDwL31T8wdXtIKPpci4UQ19g243276 intact-crc:80C47FB46444947C|rigid:h2HMig7ZRvDmsw03tjSmkbaEIFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83995 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1587832|ensemblbacteria:AAC65984 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y1032_trepa(display_long)|uniprotkb:TP_1032(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587847|imex:IM-9152-2937 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR024045|ensemblbacteria:AAC65984(transcript)|ensemblbacteria:TP_1032(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882476.1|interpro:IPR038690 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1032; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:KPVDDwL31T8wdXtIKPpci4UQ19g243276 intact-crc:14BD2D6F06CD8B11|rigid:l0VtBvpFvTH2J6GC4nZNbCws3Vk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83392 uniprotkb:O83096 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 intact:EBI-1587865|ensemblbacteria:AAC65052|ensemblbacteria:AGN75277 psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:o83096_trepa(display_long)|uniprotkb:TP_0057(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587868|imex:IM-9152-2940 author score:0.763532506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005661(Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit)|ensemblbacteria:AAC65052(transcript)|ensemblbacteria:AGN75277(transcript)|ensemblbacteria:TP_0057(gene)|ensemblbacteria:TPANIC_0057(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|refseq:WP_010881506.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0057; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 rogid:d83L5IphPMkQCtN9TgBgqoH3UHA243276 intact-crc:7B2AD28780696F2B|rigid:mXZp7in+CQbTVzXTkREM66plCJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83995 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1587832|ensemblbacteria:AAC65984 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y1032_trepa(display_long)|uniprotkb:TP_1032(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587859|imex:IM-9152-2939 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR024045|ensemblbacteria:AAC65984(transcript)|ensemblbacteria:TP_1032(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882476.1|interpro:IPR038690 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1032; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:KPVDDwL31T8wdXtIKPpci4UQ19g243276 intact-crc:7D8888EDB8FB7EF4|rigid:eCxP76XbntXxaQMOWyY2V6IrQbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83392 uniprotkb:O83544 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 intact:EBI-1584047|ensemblbacteria:AAC65519 psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:vati2_trepa(display_long)|uniprotkb:atpI2(gene name)|psi-mi:atpI2(display_short)|uniprotkb:V-ATPase subunit I 2(gene name synonym)|uniprotkb:TP_0533(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587880|imex:IM-9152-2942 author score:0.763532506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|ensemblbacteria:AAC65519(transcript)|ensemblbacteria:TP_0533(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0533; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 rogid:fb0RMVb84Z3iOv1PFnWFVayWikI243276 intact-crc:ADE6518742922A97|rigid:A6m80Ep97gmWXoFBN2kQZ8z/Gbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83096 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1587865|ensemblbacteria:AAC65052|ensemblbacteria:AGN75277 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83096_trepa(display_long)|uniprotkb:TP_0057(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587874|imex:IM-9152-2941 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR005661(Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit)|ensemblbacteria:AAC65052(transcript)|ensemblbacteria:AGN75277(transcript)|ensemblbacteria:TP_0057(gene)|ensemblbacteria:TPANIC_0057(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|refseq:WP_010881506.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0057; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:d83L5IphPMkQCtN9TgBgqoH3UHA243276 intact-crc:04BE10009046B214|rigid:Xen/B0+x9zBwhKWKyoxM8E6oOww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56338 uniprotkb:O83392 intact:EBI-1198669|intact:EBI-1587892|ensemblbacteria:AAC65680 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:flha_trepa(display_long)|uniprotkb:flhA(gene name)|psi-mi:flhA(display_short)|uniprotkb:TP_0714(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587896|imex:IM-9152-2944 author score:0.763532506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR042193|interpro:IPR042194|interpro:IPR042196|interpro:IPR006301(Flagellar biosynthesis protein FlhA)|interpro:IPR001712(Type III secretion system FHIPEP)|refseq:WP_010882159.1|ensemblbacteria:AAC65680(transcript)|ensemblbacteria:TP_0714(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0714; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mmHyEBUe+1ih63QrM0KME43PHpc243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:B5209C9CF7D73F19|rigid:lGSrsfI7p+Bq4cTgamHMgX41iNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83544 uniprotkb:O83887 intact:EBI-1584047|ensemblbacteria:AAC65519 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:vati2_trepa(display_long)|uniprotkb:atpI2(gene name)|psi-mi:atpI2(display_short)|uniprotkb:V-ATPase subunit I 2(gene name synonym)|uniprotkb:TP_0533(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587886|imex:IM-9152-2943 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|ensemblbacteria:AAC65519(transcript)|ensemblbacteria:TP_0533(gene) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0533; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fb0RMVb84Z3iOv1PFnWFVayWikI243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:809B51D2FF939F77|rigid:f96T3OSnqjEg2DzBiHPRmjY6SNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83972 uniprotkb:O83948 intact:EBI-1587715|ensemblbacteria:AAC65956 intact:EBI-1587908|ensemblbacteria:AAC65941 psi-mi:rir1_trepa(display_long)|uniprotkb:nrdA(gene name)|psi-mi:nrdA(display_short)|uniprotkb:Ribonucleotide reductase(gene name synonym)|uniprotkb:TP_1008(locus name) psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587911|imex:IM-9152-2946 author score:0.762027671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039718|interpro:IPR005144(ATP-cone)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|ensemblbacteria:AAC65956(transcript)|ensemblbacteria:TP_1008(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|refseq:WP_010882452.1 ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_1008|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6N1DBDuvOW96+g2vP5P4UxqeXFY243276 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 intact-crc:EFA9391DD833E0A4|rigid:4B5vqTtUATByhwl//YAFwAShqek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56338 uniprotkb:O83706 intact:EBI-1198669|intact:EBI-1587892|ensemblbacteria:AAC65680 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:flha_trepa(display_long)|uniprotkb:flhA(gene name)|psi-mi:flhA(display_short)|uniprotkb:TP_0714(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587902|imex:IM-9152-2945 author score:0.753673246 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR042193|interpro:IPR042194|interpro:IPR042196|interpro:IPR006301(Flagellar biosynthesis protein FlhA)|interpro:IPR001712(Type III secretion system FHIPEP)|refseq:WP_010882159.1|ensemblbacteria:AAC65680(transcript)|ensemblbacteria:TP_0714(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0714; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mmHyEBUe+1ih63QrM0KME43PHpc243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:F19FA3480C7BB896|rigid:Xa3R/c+oFarwls28VCbZ8+9TC4w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83948 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1587908|ensemblbacteria:AAC65941 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587926|imex:IM-9152-2948 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 intact-crc:32AABBA1474FA98E|rigid:gKYMhTWYHQgshQUVyjAdd2JNi7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83948 uniprotkb:O83459 intact:EBI-1587908|ensemblbacteria:AAC65941 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587917|imex:IM-9152-2947 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:0E9424A50F7C6B11|rigid:lZ9fxg1pgeAEqRgrz34e4DsochA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83948 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1587908|ensemblbacteria:AAC65941 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587938|imex:IM-9152-2950 author score:0.461234739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 intact-crc:75A3A1683ED2DE8B|rigid:gqvAISzI4mEJlmrHQYwkaRCrocU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83948 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1587908|ensemblbacteria:AAC65941 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587932|imex:IM-9152-2949 author score:0.494810066 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 intact-crc:F82EDD31740E09A0|rigid:5jW2gHtc2/ndBu31ok7OxeqsU5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83070 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587950|imex:IM-9152-2952 author score:0.760411365 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0026|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:DD0E8DEDA289E672|rigid:41HJoUP/rjDJh/7I9LdeWxosi/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83948 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1587908|ensemblbacteria:AAC65941 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y983_trepa(display_long)|uniprotkb:TP_0983(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587944|imex:IM-9152-2951 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65941(transcript)|ensemblbacteria:TP_0983(gene)|refseq:WP_010882427.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0983; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:S91r61DQnn1gXyo5Z6qWU1Q0bY0243276 intact-crc:C26486BBE32325F9|rigid:+jAZjtmdoGc8j12EpvpJ0BLSUIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83638 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587959|imex:IM-9152-2953 author score:0.759046931 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:769DAB395A2DDB4E|rigid:vyKNYFNAneCdBG5zcR4LIrWL5EM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83847 uniprotkb:O83638 intact:EBI-1198567|intact:EBI-1583350|ensemblbacteria:AAC65840|ensemblbacteria:AGN76046 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:o83847_trepa(display_long)|uniprotkb:TP_0877(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587965|imex:IM-9152-2954 author score:0.672536135 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR037522|refseq:WP_010882320.1|ensemblbacteria:AAC65840(transcript)|ensemblbacteria:AGN76046(transcript)|ensemblbacteria:TP_0877(gene)|ensemblbacteria:TPANIC_0877(gene) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0877|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+QpyFXrHDZlRcsvImMZ76wZft48243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:F1D4A0A5106DB7AE|rigid:QWAB5BGC47ksHGgJ5/lLwtJhe0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83130 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587971|imex:IM-9152-2955 author score:0.619104783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:AD9EF346A125A30A|rigid:N/m1b6iT1WBym+nsjhPGY6xQNhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83350 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198551|intact:EBI-1582539|ensemblbacteria:AAC65318|ensemblbacteria:AGN75529 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83350_trepa(display_long)|uniprotkb:TP_0330(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587986|imex:IM-9152-2957 author score:0.493347726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|refseq:WP_010881778.1|ensemblbacteria:AAC65318(transcript)|ensemblbacteria:AGN75529(transcript)|ensemblbacteria:TP_0330(gene)|ensemblbacteria:TPANIC_0330(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0330|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:543Nc2aN8TUU+I12cVCUNdQWKOw243276 intact-crc:0D052C121F27A43F|rigid:3+QFSsFvCGHVvFr2+b2KBNpTOKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83823 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198562|intact:EBI-1587981|ensemblbacteria:AAC65821 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:y851_trepa(display_long)|uniprotkb:TP_0851(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587977|imex:IM-9152-2956 author score:0.500077952 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR032533|refseq:WP_010882295.1|ensemblbacteria:AAC65821(transcript)|ensemblbacteria:TP_0851(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0851|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:yYNcG8LV5WKTvfnXiuZ67XoRCWY243276 intact-crc:CE8905550D896AFD|rigid:Snx+8VcR8uCz788AsIS2Vv9fGyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83327 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198543|intact:EBI-1583552|ensemblbacteria:AAC65292 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:pyrg_trepa(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:TP_0305(locus name)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587998|imex:IM-9152-2959 author score:0.479896938 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR033828|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|refseq:WP_010881754.1|ensemblbacteria:AAC65292(transcript)|ensemblbacteria:TP_0305(gene)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0305|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:APACO59bBWxloqEuy3KSnF0gPp8243276 intact-crc:20834BFE79801AB9|rigid:oFJqL5YP6xrQjKTFppNhLlg9ZZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96115 uniprotkb:O83638 intact:EBI-1198311|uniprotkb:O83197|intact:EBI-1581520|ensemblbacteria:AAC65150 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:ruvb_trepa(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:TP_0162(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1587992|imex:IM-9152-2958 author score:0.48661991 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|refseq:WP_010881609.1|ensemblbacteria:AAC65150(transcript)|ensemblbacteria:TP_0162(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445 interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0162|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pKRvyji0nd7AkF5U2AAlQB988W0243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:54A98165808A7A2C|rigid:d+q24A7nuHW2jluz2V/oYgNT7cQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83638 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588004|imex:IM-9152-2960 author score:0.47914415 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:F4BA67719D718166|rigid:XVO9yiL3/oiklffX2W4Jm5FPjkc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83103 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588016|imex:IM-9152-2962 author score:0.453101882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 intact-crc:193C10FEF26B9E89|rigid:W02sz9bPFI3ZQ2SWKCPXSMcsUVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83158 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588010|imex:IM-9152-2961 author score:0.459781317 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:9CC706BB19511E8E|rigid:ohOy54QrbL3EY8lYFFLyn+Xg5UM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83126 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588022|imex:IM-9152-2963 author score:0.453101882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:045ADF6A3D63C5F0|rigid:aRiUaowTsBu8lwqvjceoC2aY5e4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83195 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588028|imex:IM-9152-2964 author score:0.406946508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:DAB31EE68701645F|rigid:+T/0sQ99u8iKFMjSizTZjV2To3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:P45685 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588040|imex:IM-9152-2966 author score:0.387609851 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:FB54A38753A562A3|rigid:kvv+rY/A+x7DJAAxvfaD3CQOg+4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:P21992 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588034|imex:IM-9152-2965 author score:0.389398395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:2E8805AEC44E917C|rigid:aFwJcaemrrFKTTns3PY9g+7DT7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83927 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588046|imex:IM-9152-2967 author score:0.35093419 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:E0BD856E6252ADAB|rigid:iVsYO5GeJzHH4AbS058PX2Q0IhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83638 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588052|imex:IM-9152-2968 author score:0.331884828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:1775D08534362DCE|rigid:l4tjS8LjWj75ed8FSHwFJ2en+h4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83804 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588058|imex:IM-9152-2969 author score:0.275100343 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:0CF929B4865D094C|rigid:zdDNJOrfky4qa+lE7n4Xbmz4kDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83970 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588064|imex:IM-9152-2970 author score:0.23914829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:8598A5D781DC5059|rigid:erzTTdtN8fIc+uFnD8OgQeUYLdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83638 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588070|imex:IM-9152-2971 author score:0.142338017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:F6FB8BACC3147959|rigid:/oErM8hntOo/eUrvkGOyU7Dcaaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83638 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588076|imex:IM-9152-2972 author score:0.122923831 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:4B88B3ACD3B90FD0|rigid:s4QCn33E971EDuB53Eat2dIHK44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83745 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588088|imex:IM-9152-2974 author score:0.051424039 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:E9E894FF5BCF9B9D|rigid:JXDN3JHLU0QurzTwR43O3lqpplo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83312 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588082|imex:IM-9152-2973 author score:0.114477825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:38249632633757B1|rigid:Eb3WY3+T4lvApRUni+SNE3SLpPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83958 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588100|imex:IM-9152-2976 author score:0.000637063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:411FB522781BCB13|rigid:x+cakMRBybuJJpMIMXWxeKu1oCk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83638 uniprotkb:O83954 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588094|imex:IM-9152-2975 author score:0.008011676 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0630; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:042DA7F878CBAA4F|rigid:8nSOqHliyCXytaHhwpOx1+fLA9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83766 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1588106|ensemblbacteria:AAC65762 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:y787_trepa(display_long)|uniprotkb:TP_0787(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588115|imex:IM-9152-2978 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 ensemblbacteria:AAC65762(transcript)|ensemblbacteria:TP_0787(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882232.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0787; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:p7+0BnrJEzqd5MCZgqoU3l8/vDY243276 intact-crc:7AD059F23114285A|rigid:RcRlcU4oMee9Hh+44tDN5Es6Xhs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83766 uniprotkb:O83890 intact:EBI-1588106|ensemblbacteria:AAC65762 intact:EBI-1583720|ensemblbacteria:AAC65878 psi-mi:y787_trepa(display_long)|uniprotkb:TP_0787(locus name) psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588109|imex:IM-9152-2977 author score:0.760336541 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65762(transcript)|ensemblbacteria:TP_0787(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882232.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0787; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p7+0BnrJEzqd5MCZgqoU3l8/vDY243276 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 intact-crc:236E3ED7865F468A|rigid:TvDL90rUuzrqEQBgp1Y5+ecIEGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83766 uniprotkb:O83954 intact:EBI-1588106|ensemblbacteria:AAC65762 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y787_trepa(display_long)|uniprotkb:TP_0787(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588127|imex:IM-9152-2980 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65762(transcript)|ensemblbacteria:TP_0787(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882232.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0787; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p7+0BnrJEzqd5MCZgqoU3l8/vDY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:BDCDF3661737325A|rigid:RIxP07IQWZ/YPKON59FLv0LgT7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83766 uniprotkb:O83877 intact:EBI-1588106|ensemblbacteria:AAC65762 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y787_trepa(display_long)|uniprotkb:TP_0787(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588121|imex:IM-9152-2979 author score:0.165413283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65762(transcript)|ensemblbacteria:TP_0787(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882232.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0787; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p7+0BnrJEzqd5MCZgqoU3l8/vDY243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C58EC2EB5E953CD3|rigid:EVA9RPXbYGOoRo4i5hdy9dKCSdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83702 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588139|imex:IM-9152-2982 author score:0.758949018 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:B4184332A3337403|rigid:r5ORUWloKznCdH5qP8O5Pl6XHUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83570 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588133|imex:IM-9152-2981 author score:0.760044059 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0095; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:7FDBE98F38443244|rigid:XPxEzZIAQmzAbJKD7I47EwWYoMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83647 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588151|imex:IM-9152-2984 author score:0.519643121 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:97DC77D952916D53|rigid:py6utSXckdNjnKAemKUwno6jLD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83647 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588145|imex:IM-9152-2983 author score:0.673652661 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:F37FD894683275B0|rigid:ef69Ph6wwd1FEedYYpoePNpUHhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83398 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588157|imex:IM-9152-2985 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:3E11872535A86A76|rigid:HgSWrVIUjuiM2tGyeOAjIeb4l6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83413 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588169|imex:IM-9152-2987 author score:0.108892141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:8C15409417B63AAE|rigid:yr03q5iL55wVbyi/C/Y8ye92vQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83647 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588163|imex:IM-9152-2986 author score:0.285463752 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:CBF6DDBD2856148A|rigid:ukHvhvwwgwYa8Z2R50u+nxy3+ww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83647 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588181|imex:IM-9152-2989 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:9CBD79172B351260|rigid:pBhAq5vC7PZo3dXQgqFppHOjRpg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83745 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588175|imex:IM-9152-2988 author score:0.079065229 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:CBF77CE8BDF3512B|rigid:grcRUokMAHV+o7J3iSWKYM/i7qs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83647 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588193|imex:IM-9152-2991 author score:0.001682488 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:18BF75A04392A1DF|rigid:ybnQjNFPzH1bmHQiOOjXLzlIOTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83282 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588187|imex:IM-9152-2990 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0641; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:BC7E96C0032BBAD7|rigid:OfhgOVNT2BYgdVVc6Ekz01ZVBwQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83082 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1588199|ensemblbacteria:AAC65041 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y041_trepa(display_long)|uniprotkb:TP_0041(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588208|imex:IM-9152-2993 author score:0.616011689 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65041(transcript)|ensemblbacteria:TP_0041(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0041; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:gGsgLFIGy48ra4zm0DebMLmZoZg243276 intact-crc:34661894B51897A1|rigid:pD+FJFSmJXUMV8zsdjdVi0i7EDw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07884 uniprotkb:O83082 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 intact:EBI-1588199|ensemblbacteria:AAC65041 psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:y041_trepa(display_long)|uniprotkb:TP_0041(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588202|imex:IM-9152-2992 author score:0.758727507 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 ensemblbacteria:AAC65041(transcript)|ensemblbacteria:TP_0041(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0041; PREY protein TP_0727|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 rogid:gGsgLFIGy48ra4zm0DebMLmZoZg243276 intact-crc:4CB3738FBDD15CB2|rigid:JYRDiYAim2ARtHnAGVo5Vk8d72E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83082 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1588199|ensemblbacteria:AAC65041 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y041_trepa(display_long)|uniprotkb:TP_0041(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588226|imex:IM-9152-2996 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65041(transcript)|ensemblbacteria:TP_0041(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0041; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:gGsgLFIGy48ra4zm0DebMLmZoZg243276 intact-crc:B3246800F6C04C41|rigid:Dluh7WrYjC255emXbXRVZwebQDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83082 uniprotkb:O83305 intact:EBI-1588199|ensemblbacteria:AAC65041 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y041_trepa(display_long)|uniprotkb:TP_0041(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588220|imex:IM-9152-2995 author score:0.391095335 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65041(transcript)|ensemblbacteria:TP_0041(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0041; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gGsgLFIGy48ra4zm0DebMLmZoZg243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:D06DFBC9A280B8BA|rigid:svBBhQFxeMP1D1L1DCHA03KssYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83082 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1588199|ensemblbacteria:AAC65041 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y041_trepa(display_long)|uniprotkb:TP_0041(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588214|imex:IM-9152-2994 author score:0.510472021 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65041(transcript)|ensemblbacteria:TP_0041(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0041; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:gGsgLFIGy48ra4zm0DebMLmZoZg243276 intact-crc:78416DB63FD9C1BB|rigid:uANMXUkoO6ZpvyYtqLjbw8RtwMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74935 uniprotkb:O83909 intact:EBI-1588232|uniprotkb:O83370|ensemblbacteria:AAC65335 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:proa_trepa(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:TP_0350(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588236|imex:IM-9152-2997 author score:0.7586372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|ensemblbacteria:AAC65335(transcript)|ensemblbacteria:TP_0350(gene)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_014342789.1|refseq:WP_010881798.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0350; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:SmZEOjILLapGjLFBum6xUcRdepI243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:70DC85C6957CC61C|rigid:ey+/Uf7XNbZnmC9V9IvCtER2nkQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83600 uniprotkb:O30405 intact:EBI-1586853|ensemblbacteria:AAC65566 intact:EBI-1198903|intact:EBI-1588248|ensemblbacteria:AAC65246 psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:glpq_trepa(display_long)|uniprotkb:glpQ(gene name)|psi-mi:glpQ(display_short)|uniprotkb:glp(gene name synonym)|uniprotkb:TP_0257(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588252|imex:IM-9152-2999 author score:0.757111122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 refseq:WP_010881706.1|interpro:IPR017946|interpro:IPR030395|ensemblbacteria:AAC65246(transcript)|ensemblbacteria:TP_0257(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008889"(glycerophosphodiester phosphodiesterase activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0257|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 rogid:cOoFtwqIopb3hvTptL8uBHpkpXw243276 intact-crc:B9F8CDF167183563|rigid:M+GVTYpk4EUjWfuToYYgeG6rENQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P74935 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1588232|uniprotkb:O83370|ensemblbacteria:AAC65335 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:proa_trepa(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:TP_0350(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588242|imex:IM-9152-2998 author score:0.003934516 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|ensemblbacteria:AAC65335(transcript)|ensemblbacteria:TP_0350(gene)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_014342789.1|refseq:WP_010881798.1|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0350; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:SmZEOjILLapGjLFBum6xUcRdepI243276 intact-crc:0DD130AC42F89E0A|rigid:nwaBRXaOjktO+lsfDjCymdTyKTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83600 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1586853|ensemblbacteria:AAC65566 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588267|imex:IM-9152-3001 author score:0.709839301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 intact-crc:44E5684C09581E01|rigid:aiKgc89hhv0eUgq7VKWnSL+Cm20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83600 uniprotkb:O83310 intact:EBI-1586853|ensemblbacteria:AAC65566 intact:EBI-1588258|ensemblbacteria:AAC65268 psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588261|imex:IM-9152-3000 author score:0.726188783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 intact-crc:DAA64461E49ABCC8|rigid:zUuHwyeuWdu4S+nC/Fe9JKlXh80 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83600 uniprotkb:O83667 intact:EBI-1586853|ensemblbacteria:AAC65566 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588285|imex:IM-9152-3004 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B04DF75EEDA85F17|rigid:rFG3XiGkj8MPmtKZk2fq+h0FiZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83600 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1586853|ensemblbacteria:AAC65566 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588279|imex:IM-9152-3003 author score:0.287163122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 intact-crc:0CDD56C4AE202911|rigid:HPpHz98xonhl1x3CRvEqZbtlcY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83600 uniprotkb:O83463 intact:EBI-1586853|ensemblbacteria:AAC65566 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:hprk_trepa(display_long)|uniprotkb:hprK(gene name)|psi-mi:hprK(display_short)|uniprotkb:ptsK(gene name synonym)|uniprotkb:"HPr(Ser) kinase/phosphorylase"(gene name synonym)|uniprotkb:TP_0591(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588273|imex:IM-9152-3002 author score:0.461234739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003755("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase")|interpro:IPR011104("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, C-terminal")|interpro:IPR011126("Signal transduction serine kinase/phosphorylase, HPr(Ser) kinase, N-terminal")|ensemblbacteria:AAC65566(transcript)|ensemblbacteria:TP_0591(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|interpro:IPR028979|interpro:IPR027417 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0591; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XiI0PTy+JnkzeCWcv0gd7NNfBe4243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:9F5353969FDAB858|rigid:N3MQlhf7UjsMNVhR0WJ5sGijVG4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56345 uniprotkb:O83798 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 intact:EBI-1586366|ensemblbacteria:AAC65793|ensemblbacteria:AGN75996 psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:o83798_trepa(display_long)|uniprotkb:dacA(gene name)|psi-mi:dacA(display_short)|uniprotkb:Cyclic-di-AMP synthase(gene name synonym)|uniprotkb:TP_0826(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588294|imex:IM-9152-3005 author score:0.755487397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 interpro:IPR014046(Conserved hypothetical protein CHP00159)|interpro:IPR003390(Protein of unknown function DUF147)|ensemblbacteria:AAC65793(transcript)|ensemblbacteria:AGN75996(transcript)|ensemblbacteria:TP_0826(gene)|ensemblbacteria:TPANIC_0826(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019932"(second-messenger-mediated signaling)|refseq:WP_010882270.1|interpro:IPR034701|interpro:IPR036888 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0826|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 rogid:oo7v+ysrG+DvRWOMaB6TtayNVHA243276 intact-crc:0CBF9EE5E573B913|rigid:iuWbkrxtqWSZXaScK0i2I8RVL2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83392 uniprotkb:Q56345 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588312|imex:IM-9152-3008 author score:0.702424822 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 intact-crc:95C50969EF988C12|rigid:IEXJpFmOz0QGl234h7FWCvj96Po false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83354 uniprotkb:Q56345 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588306|imex:IM-9152-3007 author score:0.735051743 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0334|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 intact-crc:D01587D25547B466|rigid:F3pw9u7Oqf9wzi+UYEbEXIJ64Sg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56345 uniprotkb:P74932 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 intact:EBI-1198688|intact:EBI-1581558|ensemblbacteria:AAC65682 psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:flir_trepa(display_long)|uniprotkb:fliR(gene name)|psi-mi:fliR(display_short)|uniprotkb:TP_0716(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588300|imex:IM-9152-3006 author score:0.750479971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 interpro:IPR006303(Flagellar biosynthesis protein FliR)|interpro:IPR002010(Type III secretion system inner membrane R protein)|refseq:WP_010882161.1|ensemblbacteria:AAC65682(transcript)|ensemblbacteria:TP_0716(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0716|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 rogid:FjB+E/FbuGXCbz1BwCI7BpFVfj0243276 intact-crc:6335A5AE5D6F0FF0|rigid:5Qt2giEJ0CMIlVciRnlBlq+AzT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56345 uniprotkb:O83572 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588324|imex:IM-9152-3010 author score:0.492607984 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:44E43A0C96877E51|rigid:Ybt9Z133nYKD5Q/NRmngcpYE+F0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56345 uniprotkb:O83706 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588318|imex:IM-9152-3009 author score:0.691048678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:97E096EB69C29482|rigid:0wLr+r9RTgUfBPHHSTEkQplAp+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83184 uniprotkb:O83706 intact:EBI-1588336|ensemblbacteria:AAC65141 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:y149_trepa(display_long)|uniprotkb:TP_0149(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588339|imex:IM-9152-3012 author score:0.753673246 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65141(transcript)|ensemblbacteria:TP_0149(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881596.1 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0149; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3ixXTgu1L9HHRRglvaZMjXi767U243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:577B728A3500B63F|rigid:Ht5kk93K20ETY0g0CkHmm6uyLSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56345 uniprotkb:O83887 intact:EBI-1588291|ensemblbacteria:AAC65036|ensemblbacteria:AGN75262 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:q56345_trepa(display_long)|uniprotkb:TP_0042(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588330|imex:IM-9152-3011 author score:0.459046304 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018392|ensemblbacteria:AAC65036(transcript)|ensemblbacteria:AGN75262(transcript)|ensemblbacteria:TP_0042(gene)|ensemblbacteria:TPANIC_0042(gene)|refseq:WP_010881491.1|interpro:IPR036779 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0042; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YO4c4rCFuc2V7cpDDOkRcSExLog243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:6D21EEF475D06971|rigid:dGDy+RR8DHb2AAtpRNLBE48VCdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83392 uniprotkb:O83144 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 intact:EBI-1588351|ensemblbacteria:AAC26554 psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:o83144_trepa(display_long)|uniprotkb:TP_0106(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588354|imex:IM-9152-3014 author score:0.752034067 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000060(BCCT transporter)|ensemblbacteria:AAC26554(transcript)|ensemblbacteria:TP_0106(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071705"(nitrogen compound transport)|refseq:WP_010881555.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0106; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 rogid:4hcEfXUAv+flN0I5yaI2BhP3HWs243276 intact-crc:4C098DC6899A79E6|rigid:wDU2GJ5Og46hyYE0jCMsvP3x1ik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83184 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1588336|ensemblbacteria:AAC65141 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y149_trepa(display_long)|uniprotkb:TP_0149(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588345|imex:IM-9152-3013 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65141(transcript)|ensemblbacteria:TP_0149(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881596.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0149; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:3ixXTgu1L9HHRRglvaZMjXi767U243276 intact-crc:5A2A59664784D49D|rigid:RblH4qIiOArL11mtaCcyh1x0GBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83144 uniprotkb:O83572 intact:EBI-1588351|ensemblbacteria:AAC26554 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83144_trepa(display_long)|uniprotkb:TP_0106(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588360|imex:IM-9152-3015 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000060(BCCT transporter)|ensemblbacteria:AAC26554(transcript)|ensemblbacteria:TP_0106(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071705"(nitrogen compound transport)|refseq:WP_010881555.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0106; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4hcEfXUAv+flN0I5yaI2BhP3HWs243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:0B62C08C7BA34AAF|rigid:8X0LOGUUK5SSHsEZs8F4VVBZRoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83520 uniprotkb:O83392 intact:EBI-1588372|ensemblbacteria:AAC65495 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588382|imex:IM-9152-3025 author score:0.702424822 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:39FC1B769B3F068D|rigid:kudTvFYrraJLF4R6AmYerCFbPrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83520 uniprotkb:P96131 intact:EBI-1588372|ensemblbacteria:AAC65495 intact:EBI-1583755|ensemblbacteria:AAC65347 psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:rl28_trepa(display_long)|uniprotkb:rpmB(gene name)|psi-mi:rpmB(display_short)|uniprotkb:rpl28(gene name synonym)|uniprotkb:TP_0362(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588376|imex:IM-9152-3017 author score:0.750479971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 interpro:IPR001383(Ribosomal protein L28)|interpro:IPR034704|interpro:IPR026569|ensemblbacteria:AAC65347(transcript)|ensemblbacteria:TP_0362(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881810.1|interpro:IPR037147 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0362|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 rogid:77S9butCz8qvXZGwBHz17pmfbNk243276 intact-crc:038BF6FA1065B3CA|rigid:YS4U8VY9pmrRvbQBWFx4wYCBok8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83144 uniprotkb:O83887 intact:EBI-1588351|ensemblbacteria:AAC26554 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83144_trepa(display_long)|uniprotkb:TP_0106(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588366|imex:IM-9152-3016 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000060(BCCT transporter)|ensemblbacteria:AAC26554(transcript)|ensemblbacteria:TP_0106(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0071705"(nitrogen compound transport)|refseq:WP_010881555.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0106; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4hcEfXUAv+flN0I5yaI2BhP3HWs243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:5D5B08EDF04AAF71|rigid:CtjjQB239P/86sazazY1/uptUl4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83520 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1588372|ensemblbacteria:AAC65495 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588394|imex:IM-9152-3027 author score:0.25051666 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 intact-crc:FAAC3725C87E4780|rigid:Zc5KbGxSHw+MV1jdMd6GgxPMYj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83520 uniprotkb:O83099 intact:EBI-1588372|ensemblbacteria:AAC65495 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588388|imex:IM-9152-3026 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:5AB6E2B9F672BB27|rigid:0Uv2E8DuIIhzXehFvfK5rZo06qU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83520 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1588372|ensemblbacteria:AAC65495 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588406|imex:IM-9152-3029 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 intact-crc:79A89989047FA858|rigid:dny+C45fXCVdl1i4mQfRAE5+TRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83520 uniprotkb:O83574 intact:EBI-1588372|ensemblbacteria:AAC65495 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588400|imex:IM-9152-3028 author score:0.206071282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C3DBF9DD1B366210|rigid:6o6XafEW2zsnb3f6DkmBFwHAEy0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83478 uniprotkb:O83110 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 intact:EBI-1588418|ensemblbacteria:AAC65062 psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:clpb_trepa(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:TP_0071(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588425|imex:IM-9152-3031 author score:0.748733837 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|ensemblbacteria:AAC65062(transcript)|ensemblbacteria:TP_0071(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|refseq:WP_010881520.1|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0071; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 rogid:MldzaCk0FjW0RON/FzpvSrUvWSw243276 intact-crc:88D71FC741EB5B43|rigid:NQ6lttu3R9OgtUvymiZ+0WHG7qo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83520 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1588372|ensemblbacteria:AAC65495 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:clpp1_trepa(display_long)|uniprotkb:clpP1(gene name)|psi-mi:clpP1(display_short)|uniprotkb:clpP-1(gene name synonym)|uniprotkb:Endopeptidase Clp 1(gene name synonym)|uniprotkb:TP_0507(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588412|imex:IM-9152-3030 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR033135|ensemblbacteria:AAC65495(transcript)|ensemblbacteria:TP_0507(gene)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR029045|refseq:WP_010881956.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0507; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:2j1j/V2P0BdmD0f+RCU4VLWbJmg243276 intact-crc:0CBAEA1CE6B2199C|rigid:1qalAGnjqoJLfNDLyxT6RmBVzvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83110 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1588418|ensemblbacteria:AAC65062 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:clpb_trepa(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:TP_0071(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588437|imex:IM-9152-3033 author score:0.450769169 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|ensemblbacteria:AAC65062(transcript)|ensemblbacteria:TP_0071(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|refseq:WP_010881520.1|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0071; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:MldzaCk0FjW0RON/FzpvSrUvWSw243276 intact-crc:A62F437A4E37ECAA|rigid:jeZcPYEqM6hWS0wH6eokFr3yOys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83110 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1588418|ensemblbacteria:AAC65062 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:clpb_trepa(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:TP_0071(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588431|imex:IM-9152-3032 author score:0.690858902 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|ensemblbacteria:AAC65062(transcript)|ensemblbacteria:TP_0071(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|refseq:WP_010881520.1|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0071; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:MldzaCk0FjW0RON/FzpvSrUvWSw243276 intact-crc:04B64F40274606A8|rigid:10JBOXnHj+8z0QC1fUtYb2Ui07w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q57321 uniprotkb:O83977 intact:EBI-1588455|ensemblbacteria:AAC65649 intact:EBI-1583534|ensemblbacteria:AAC65964 psi-mi:mglc_trepa(display_long)|uniprotkb:mglC(gene name)|psi-mi:mglC(display_short)|uniprotkb:TP_0686(locus name) psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588459|imex:IM-9152-3036 author score:0.748641028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001851(Bacterial inner-membrane translocator)|interpro:IPR030158|ensemblbacteria:AAC65649(transcript)|ensemblbacteria:TP_0686(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010882131.1 ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0686; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:V1aAudrUO621lPAtWFK6oERk9PE243276 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 intact-crc:C38BF6020A38BBBD|rigid:k0uTSqbbcPM9fYENx4ZhCRIjuqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83110 uniprotkb:O83958 intact:EBI-1588418|ensemblbacteria:AAC65062 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:clpb_trepa(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:TP_0071(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588449|imex:IM-9152-3035 author score:0.002168429 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|ensemblbacteria:AAC65062(transcript)|ensemblbacteria:TP_0071(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|refseq:WP_010881520.1|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0071; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MldzaCk0FjW0RON/FzpvSrUvWSw243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:287B66E4BC3CBFD6|rigid:phYg0zUA2v7dJXpUNYTU6TX35to false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83110 uniprotkb:O83413 intact:EBI-1588418|ensemblbacteria:AAC65062 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:clpb_trepa(display_long)|uniprotkb:clpB(gene name)|psi-mi:clpB(display_short)|uniprotkb:TP_0071(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588443|imex:IM-9152-3034 author score:0.143215719 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR018368|interpro:IPR017730(Chaperonin ClpB)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR019489|interpro:IPR004176(Clp, N-terminal)|ensemblbacteria:AAC65062(transcript)|ensemblbacteria:TP_0071(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|refseq:WP_010881520.1|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0071; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MldzaCk0FjW0RON/FzpvSrUvWSw243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:20662E71609DF8B6|rigid:37hbGhZBCqsx7hqzZIfVzhQ4zY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83638 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198525|intact:EBI-1587954|ensemblbacteria:AAC65605|ensemblbacteria:AGN75811 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83638_trepa(display_long)|uniprotkb:TP_0630(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588471|imex:IM-9152-3038 author score:0.747669099 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR022642|interpro:IPR000780(MCP methyltransferase, CheR-type)|interpro:IPR022641|interpro:IPR026024|interpro:IPR029063|ensemblbacteria:AAC65605(transcript)|ensemblbacteria:AGN75811(transcript)|ensemblbacteria:TP_0630(gene)|ensemblbacteria:TPANIC_0630(gene)|go:"GO:0008983"(protein-glutamate O-methyltransferase activity)|interpro:IPR036804 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0630|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:/526tPJGzV2vEZ/7Zs2Ia9dZxjw243276 intact-crc:8379CD1AB2372119|rigid:aFwJcaemrrFKTTns3PY9g+7DT7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q57321 uniprotkb:O83958 intact:EBI-1588455|ensemblbacteria:AAC65649 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:mglc_trepa(display_long)|uniprotkb:mglC(gene name)|psi-mi:mglC(display_short)|uniprotkb:TP_0686(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588465|imex:IM-9152-3037 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001851(Bacterial inner-membrane translocator)|interpro:IPR030158|ensemblbacteria:AAC65649(transcript)|ensemblbacteria:TP_0686(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010882131.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0686; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:V1aAudrUO621lPAtWFK6oERk9PE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BF82B0F72D78CBEF|rigid:nqumwf8Jbwg3Oim/7ZeJDEES190 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:P21992 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588483|imex:IM-9152-3040 author score:0.723276969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:8DC76D2EC8FACC78|rigid:ZeoiugihZVGzYqFVIM4nHPKQRdg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83664 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198841|intact:EBI-1581667|ensemblbacteria:AAC65632 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:fliw_trepa(display_long)|uniprotkb:fliW(gene name)|psi-mi:fliW(display_short)|uniprotkb:TP_0658(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588477|imex:IM-9152-3039 author score:0.732826469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003775(Protein of unknown function DUF180)|interpro:IPR024046|refseq:WP_010882103.1|ensemblbacteria:AAC65632(transcript)|ensemblbacteria:TP_0658(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0658|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:qv/jNb+Zl6loTmisU7Q7PjIFUWo243276 intact-crc:7B594E032C326ABB|rigid:mr17QeiaQrxA4h0MRkoG62kOojs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83741 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198893|intact:EBI-1588495|ensemblbacteria:AAC65726|ensemblbacteria:AGN75933 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83741_trepa(display_long)|uniprotkb:TP_0760(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588498|imex:IM-9152-3042 author score:0.719004303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005543(PASTA)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|refseq:WP_010882205.1|ensemblbacteria:AAC65726(transcript)|ensemblbacteria:AGN75933(transcript)|ensemblbacteria:TP_0760(gene)|ensemblbacteria:TPANIC_0760(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0016020"(membrane)|interpro:IPR036138 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0760|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:1VwIquwM2EcCFCPSBYI3bC9UWSY243276 intact-crc:2D07B02BD4E1F13C|rigid:jf9oD+krqz4kdM8cBdgMQm+CLBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83411 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588489|imex:IM-9152-3041 author score:0.720983359 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 intact-crc:8C1501EE36F56FF8|rigid:C0wqhYHMcoVbEfGIHj+BPTLOrIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83700 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198870|intact:EBI-1583519|ensemblbacteria:AAC65671 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83700_trepa(display_long)|uniprotkb:TP_0702(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588510|imex:IM-9152-3044 author score:0.643950481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|ensemblbacteria:AAC65671(transcript)|ensemblbacteria:TP_0702(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0702|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:m+L0PIYpz1pXrbGDyvQbpbjJ9S4243276 intact-crc:700E6F1353641EC4|rigid:pevzTz7ZBalIP+8KWjMxPGVkXfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O52778 uniprotkb:P21992 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588504|imex:IM-9152-3043 author score:0.697547895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0640|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:0380445174BF5C16|rigid:ODQh/H23UdWIzvSDUpETX4se94M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:P21992 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588525|imex:IM-9152-3046 author score:0.468213673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0873|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:D4097DDBC28B74B9|rigid:w3imgcffcFIAuxjS3jpU5crjCqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83946 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588516|imex:IM-9152-3045 author score:0.571257876 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0981|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:70954950D0E3EDE6|rigid:j8cFUbERdihK9iyTNJ1WtJoQ3Is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83051 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588531|imex:IM-9152-3047 author score:0.375112913 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 intact-crc:EA1AEB0EB844C345|rigid:EOERdR9nygTjStsW55klrYclR2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83092 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198878|intact:EBI-1588541|ensemblbacteria:AAC65049 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rir2_trepa(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:TP_0053(locus name)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588537|imex:IM-9152-3048 author score:0.362719427 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|refseq:WP_010881502.1|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)|ensemblbacteria:AAC65049(transcript)|ensemblbacteria:TP_0053(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0053|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:z67SeoH9YUD2zHKtcxYMO/oOe9M243276 intact-crc:B1DA5350A06D031D|rigid:CYJFQ+STqd1stDTxjqRjoWwF0Ks false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83204 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198866|intact:EBI-1588551|ensemblbacteria:AAC65164 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y174_trepa(display_long)|uniprotkb:TP_0174(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588547|imex:IM-9152-3049 author score:0.362719427 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65164(transcript)|ensemblbacteria:TP_0174(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0174|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:86B3J0Sl+nAqYDos8P0Ly2l71eE243276 intact-crc:00E75B4887F2FA10|rigid:7ADKxM9eZPuErr4kFYFTGO1A8Yk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O30405 uniprotkb:P21992 intact:EBI-1198903|intact:EBI-1588248|ensemblbacteria:AAC65246 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:glpq_trepa(display_long)|uniprotkb:glpQ(gene name)|psi-mi:glpQ(display_short)|uniprotkb:glp(gene name synonym)|uniprotkb:TP_0257(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588556|imex:IM-9152-3050 author score:0.350367239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881706.1|interpro:IPR017946|interpro:IPR030395|ensemblbacteria:AAC65246(transcript)|ensemblbacteria:TP_0257(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008889"(glycerophosphodiester phosphodiesterase activity) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0257|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cOoFtwqIopb3hvTptL8uBHpkpXw243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:A309B0CB2537B00A|rigid:CfPA3OMPIEKwBH2yBU+tYf/3yFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83637 uniprotkb:P21992 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588562|imex:IM-9152-3051 author score:0.332213031 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:946F461AD390DC69|rigid:BpigKBVd7/l7jytYnaEMw0i434k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83105 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588574|imex:IM-9152-3053 author score:0.303052259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:2871847D5126BAFD|rigid:dmcBMKE4nsaWNtabOu9Fmgi7GfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83089 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588568|imex:IM-9152-3052 author score:0.308768562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:2628DDB8705F0926|rigid:C7uCGQIbtzPY0c0pGitvK76oDdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83927 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588580|imex:IM-9152-3054 author score:0.288518343 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:194EA6FE00F70174|rigid:bse5DVc8omTXjIL/K62qCJ7s5Oc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83804 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588592|imex:IM-9152-3056 author score:0.177585908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:79BED06D37E8998F|rigid:JV/pnPkKget3SHBjdCC8p6BpX2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:P21992 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588586|imex:IM-9152-3055 author score:0.264781553 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:C710CF3A52B50736|rigid:/DVl+oWRY4+M2QZTbiWORHHF7o4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:P21992 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588598|imex:IM-9152-3057 author score:0.14729363 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:B4E5DA42F043FF75|rigid:WLR0RRDtcgvtFk8ea3/7l1jey8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83709 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588604|imex:IM-9152-3058 author score:0.144910252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:E78A1A04397C8401|rigid:jHuIb+r/EY/5/QKnRYav5L4czPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83312 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588610|imex:IM-9152-3059 author score:0.11859759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:929E1705E7443BA3|rigid:mPdLnLoaFRsgrvUidH88ppw9UVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83398 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588616|imex:IM-9152-3060 author score:0.09223726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:66755AA51620B8A3|rigid:o6rYfgOqfl0t5d3Xe42jotmQYiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:P21992 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588634|imex:IM-9152-3063 author score:0.065159761 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:0C95E3F7AFC747B0|rigid:RTebt2qo1LczgczG8enQO2h+Hmg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83099 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588628|imex:IM-9152-3062 author score:0.06681904 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:A9074E958981BEFE|rigid:ZAXzd5tDLKVgrOyhDbc0Enqfu/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:P21992 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588622|imex:IM-9152-3061 author score:0.081567969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:897B11710B81D84D|rigid:SmouM7wLYyAuguewd1nOK8RxHz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83574 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588640|imex:IM-9152-3064 author score:0.045631648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:55ED6B610EBBBB3D|rigid:wsayMmicCt49Y+WQL8Ktfui7PKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83745 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588652|imex:IM-9152-3066 author score:0.03474231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:645EF059494F16AD|rigid:OiOe1Q2nbgNRxoxMB7NsqwNquAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83877 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588646|imex:IM-9152-3065 author score:0.03710527 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:6A11BE1EDA09559F|rigid:QVk4meijSPzRj8xHwIIZpV24x1Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:P21992 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588658|imex:IM-9152-3067 author score:0.024444838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:C01B5E6268E9659C|rigid:b4CocJIJi2kb+zikcUJ8PWOL/Zs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83767 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588664|imex:IM-9152-3068 author score:0.016456768 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:60F83FFE4D43DDFA|rigid:P1Hh0pX54LGVQvBQhOihd4yuYJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83958 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588682|imex:IM-9152-3071 author score:0.00079905 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:4E84B0D235028309|rigid:ZT6cdKkcIsEeZgnDKJwKmIWpFkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83954 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588676|imex:IM-9152-3070 author score:0.00457436 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:591F22B73CC185AD|rigid:QgVgtW1DogD1dOdVQEm/2YRMWdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83282 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588670|imex:IM-9152-3069 author score:0.005517782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0870; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:573D509634BEE0D0|rigid:GnwfeTSzot4HDaviwxD/U3aYPcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83882 uniprotkb:O83805 intact:EBI-1588692|ensemblbacteria:AAC65863|ensemblbacteria:AGN76080 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83882_trepa(display_long)|uniprotkb:TP_0912(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588697|imex:IM-9152-3073 author score:0.620170814 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021812|ensemblbacteria:AAC65863(transcript)|ensemblbacteria:AGN76080(transcript)|ensemblbacteria:TP_0912(gene)|ensemblbacteria:TPANIC_0912(gene)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR037522 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0912; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bNYCe7sf6+lUfbhD2gmwzL+rH5Q243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:1F8A2F776B200D4D|rigid:0lbJ6v+Fz1ft5yxG5BPPH9ddv3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O83882 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1588692|ensemblbacteria:AAC65863|ensemblbacteria:AGN76080 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:o83882_trepa(display_long)|uniprotkb:TP_0912(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588688|imex:IM-9152-3072 author score:0.746979604 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR021812|ensemblbacteria:AAC65863(transcript)|ensemblbacteria:AGN76080(transcript)|ensemblbacteria:TP_0912(gene)|ensemblbacteria:TPANIC_0912(gene)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0912; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:bNYCe7sf6+lUfbhD2gmwzL+rH5Q243276 intact-crc:6B224F3B5C78B799|rigid:a0Iy9A9QbubJYRVnidtFRwCxLsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O07895 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1588713|uniprotkb:Q7DFN5 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:o07895_trepl(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588709|imex:IM-9152-3075 author score:0.746440366 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 intact-crc:9B9008AD01C1DFC3|rigid:0tYbxyQwGMZpQ+TQj3wkR0W+DSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83882 uniprotkb:O83958 intact:EBI-1588692|ensemblbacteria:AAC65863|ensemblbacteria:AGN76080 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83882_trepa(display_long)|uniprotkb:TP_0912(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588703|imex:IM-9152-3074 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021812|ensemblbacteria:AAC65863(transcript)|ensemblbacteria:AGN76080(transcript)|ensemblbacteria:TP_0912(gene)|ensemblbacteria:TPANIC_0912(gene)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR037522 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0912; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bNYCe7sf6+lUfbhD2gmwzL+rH5Q243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:062565F633548C20|rigid:BeycmE0zKT1mBynwZzTXTp8G6Yc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O07895 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1588713|uniprotkb:Q7DFN5 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:o07895_trepl(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588724|imex:IM-9152-3077 author score:0.677514296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 intact-crc:A5DF2680E76CF8C0|rigid:5HD6M5sYxsilYT3BL6uyuYtBhQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07895 uniprotkb:O83475 intact:EBI-1588713|uniprotkb:Q7DFN5 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o07895_trepl(display_long) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588718|imex:IM-9152-3076 author score:0.706196889 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:A74A6F696662A936|rigid:Z6KUDswun0g9kDCisvle3drKwh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O07895 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1588713|uniprotkb:Q7DFN5 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o07895_trepl(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588730|imex:IM-9152-3078 author score:0.464728649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 intact-crc:A73EBD3AC9992418|rigid:9rIy3vtBgmYmRMRyVWO5I5EA/L0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07895 uniprotkb:O83099 intact:EBI-1588713|uniprotkb:Q7DFN5 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o07895_trepl(display_long) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588736|imex:IM-9152-3079 author score:0.356548473 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:2170320194857C03|rigid:woMa1uLXzG5+SFInUZxHiaoapPc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07895 uniprotkb:O83282 intact:EBI-1588713|uniprotkb:Q7DFN5 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o07895_trepl(display_long) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588742|imex:IM-9152-3080 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:2AADA8CE6817A84D|rigid:Y51krD2yQPs9pCMXmf+GnriMGAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O07895 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1588713|uniprotkb:Q7DFN5 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o07895_trepl(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588748|imex:IM-9152-3081 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 intact-crc:8A3C0FB3CA39E901|rigid:lbFElhmtMOuPwYodGXaWmzKbORE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O07895 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1588713|uniprotkb:Q7DFN5 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o07895_trepl(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588754|imex:IM-9152-3082 author score:0.001917578 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0820; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:4IuKhXACRXdPrrumUHap4+4Vh2g160 intact-crc:2B5B25CCD991F225|rigid:8Vyv8KGNMKWheR4NPPSBfociXZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83863 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1588760|ensemblbacteria:AAC65850 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:rimp_trepa(display_long)|uniprotkb:rimP(gene name)|psi-mi:rimP(display_short)|uniprotkb:TP_0893(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588763|imex:IM-9152-3083 author score:0.746185698 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR003728(Protein of unknown function DUF150)|ensemblbacteria:AAC65850(transcript)|ensemblbacteria:TP_0893(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042274"(ribosomal small subunit biogenesis)|refseq:WP_010882336.1|interpro:IPR028989|interpro:IPR028998|interpro:IPR035956 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0893; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:thFNlOuhIDBPb08ETMTpgNz+UG8243276 intact-crc:DD339D8DD413F565|rigid:lyi2zA0ULZxfCUSGlaT2m7bbYuw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83071 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1588775|ensemblbacteria:AAC65023|ensemblbacteria:AGN75248 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83071_trepa(display_long)|uniprotkb:TP_0027(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588778|imex:IM-9152-3085 author score:0.744417951 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|ensemblbacteria:AAC65023(transcript)|ensemblbacteria:AGN75248(transcript)|ensemblbacteria:TP_0027(gene)|ensemblbacteria:TPANIC_0027(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0027; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:Iz+44M3sbxvqLScc5Jg2fDHL1jk243276 intact-crc:513C2C208DB8CB54|rigid:Gj7Kk/dHDNhiCdL4RtXg6KXCvoM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83518 uniprotkb:P16055 intact:EBI-1581717|ensemblbacteria:AAC65489|ensemblbacteria:AGN75694 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:o83518_trepa(display_long)|uniprotkb:TP_0505(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588769|imex:IM-9152-3084 author score:0.745217291 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR022672|ensemblbacteria:AAC65489(transcript)|ensemblbacteria:AGN75694(transcript)|ensemblbacteria:TP_0505(gene)|ensemblbacteria:TPANIC_0505(gene)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0006096"(glycolytic process)|refseq:WP_010881954.1|interpro:IPR043129 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0505; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LAsIHHUGP2Wi9tX/xsn5LeL/gyw243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:D439BA572BEFCBED|rigid:uk5bzD1ffEQTw1tTKcV09JolOBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83071 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1588775|ensemblbacteria:AAC65023|ensemblbacteria:AGN75248 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83071_trepa(display_long)|uniprotkb:TP_0027(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588784|imex:IM-9152-3086 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR005170(Transporter-associated region)|ensemblbacteria:AAC65023(transcript)|ensemblbacteria:AGN75248(transcript)|ensemblbacteria:TP_0027(gene)|ensemblbacteria:TPANIC_0027(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0027; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:Iz+44M3sbxvqLScc5Jg2fDHL1jk243276 intact-crc:B61CF38E8F362E21|rigid:uc7oGIb0IYUeyBbYDyh06Gq7R0s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83236 uniprotkb:P96116 intact:EBI-1588794|ensemblbacteria:AAC65190 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 psi-mi:rs5_trepa(display_long)|uniprotkb:rpsE(gene name)|psi-mi:rpsE(display_short)|uniprotkb:TP_0206(locus name) psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588798|imex:IM-9152-3087 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005712(Ribosomal protein S5, bacterial-type)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR018192|ensemblbacteria:AAC65190(transcript)|ensemblbacteria:TP_0206(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881653.1 interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0206|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ntL0QvV/7HixSgQ8nPPLUHmuStU243276 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 intact-crc:D75176F97056607E|rigid:Tnruhi20VgH4YsH86SQRxM6iYos false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96116 uniprotkb:O83561 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 intact:EBI-1588808|ensemblbacteria:AAC65535 psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:mnme_trepa(display_long)|uniprotkb:mnmE(gene name)|psi-mi:mnmE(display_short)|uniprotkb:thdF(gene name synonym)|uniprotkb:trmE(gene name synonym)|uniprotkb:TP_0550(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588804|imex:IM-9152-3088 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 interpro:IPR018948|interpro:IPR004520(tRNA modification GTPase TrmE)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR031168|ensemblbacteria:AAC65535(transcript)|ensemblbacteria:TP_0550(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR006073(GTP1/OBG)|interpro:IPR025867|refseq:WP_010881997.1|interpro:IPR027417|interpro:IPR027266|interpro:IPR027368 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0550|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 rogid:foBg7zl5evdLmPvfxaWYzHDA+YE243276 intact-crc:96A46F58AABC7B23|rigid:XKTYN2shXwTCXO7oh+tyG33Xles false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:P96116 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588814|imex:IM-9152-3089 author score:0.671604151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 intact-crc:A33F271848A138E2|rigid:CjNyIZWRVy/RD0FiXqnus7h2Kbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96116 uniprotkb:O83805 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588820|imex:IM-9152-3090 author score:0.544134798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:4F48C259505DC393|rigid:e/R79q4mfmporOtRIv36MFhpxd8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:P96116 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588826|imex:IM-9152-3091 author score:0.524039556 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 intact-crc:7E82BD69EC61EDFE|rigid:iwaBb4eFyTsyH46Cx+zyZ5443IY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96116 uniprotkb:O83927 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588832|imex:IM-9152-3092 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:66E35FABB202D138|rigid:b6OXbR+LmQKWEIBwtAyAm5yHwuk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:P96116 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588838|imex:IM-9152-3093 author score:0.177993097 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 intact-crc:64857E8E06A65C09|rigid:yS8qKkl/6/VUN4wZJur0CgTzFgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P96116 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1588790|uniprotkb:Q56329|ensemblbacteria:AAC65151 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:troa_trepa(display_long)|uniprotkb:troA(gene name)|psi-mi:troA(display_short)|uniprotkb:troMP1(gene name synonym)|uniprotkb:Tromp-1(gene name synonym)|uniprotkb:TP_0163(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588844|imex:IM-9152-3094 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006127(Periplasmic solute binding protein)|interpro:IPR006128(Adhesion lipoprotein)|interpro:IPR006129(Adhesin B)|rcsb pdb:1K0F|rcsb pdb:1TOA|ensemblbacteria:AAC65151(transcript)|ensemblbacteria:TP_0163(gene)|go:"GO:0006829"(zinc ion transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0042597"(periplasmic space)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881610.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0163; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:vA0gHAv3984MtInGUCnqUbiTc6k243276 intact-crc:57C4FE868F39F851|rigid:OUAZErtdRNojoZcIEfmgu/CAShU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83483 uniprotkb:O83363 intact:EBI-1588857|ensemblbacteria:AAC65451|ensemblbacteria:AGN75662 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 psi-mi:o83483_trepa(display_long)|uniprotkb:TP_0470(locus name) psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588850|imex:IM-9152-3095 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881919.1|ensemblbacteria:AAC65451(transcript)|ensemblbacteria:AGN75662(transcript)|ensemblbacteria:TP_0470(gene)|ensemblbacteria:TPANIC_0470(gene) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0470|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FmjCDHpHym8BWZ/bNS59M6fe/D4243276 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 intact-crc:975F18F0BF4E0EEC|rigid:qN7AomSyotFdCL6WIn0zMr97iAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83363 uniprotkb:O83607 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 intact:EBI-1588862|ensemblbacteria:AAC65581 psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:y598_trepa(display_long)|uniprotkb:TP_0598(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588865|imex:IM-9152-3096 author score:0.74372906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblbacteria:AAC65581(transcript)|ensemblbacteria:TP_0598(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0598|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 rogid:36a9BGsnoVqLEXf5W9sWbYfBS60243276 intact-crc:80677408009A1652|rigid:gVXoAiDnqiIvTXN2IMQpsNq381g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83363 uniprotkb:O83982 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588877|imex:IM-9152-3098 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:94E9804E5621D1D6|rigid:vecaO7Ii1T7hZgwjJMcG0rVXyPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83363 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588871|imex:IM-9152-3097 author score:0.544134798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 intact-crc:66809EFAB0B29FA7|rigid:DceOvsaCmxzehP2QIpPfWl0LkUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83363 uniprotkb:O83667 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588889|imex:IM-9152-3100 author score:0.113290143 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:EC98977BE8A76C87|rigid:xNIpPRuVhCeEHaPyTatKfa9QZEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83363 uniprotkb:P21992 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588883|imex:IM-9152-3099 author score:0.262210377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:AC8DEF2A4661E5A9|rigid:yKQ/qZrOMQtpCE+UOH5ZcX26faA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83363 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588895|imex:IM-9152-3101 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 intact-crc:35FB4D1BA74816AE|rigid:kPv2ERnYWPTnj/hWJa24919o65I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83363 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1588854|ensemblbacteria:AAC65331|ensemblbacteria:AGN75541 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83363_trepa(display_long)|uniprotkb:TP_0343(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588901|imex:IM-9152-3102 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011257(DNA glycosylase)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR003265(HhH-GPD)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR023170|ensemblbacteria:AAC65331(transcript)|ensemblbacteria:AGN75541(transcript)|ensemblbacteria:TP_0343(gene)|ensemblbacteria:TPANIC_0343(gene)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0006284"(base-excision repair)|refseq:WP_010881791.1|interpro:IPR044298 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0343; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:oByIyywZnma47F7POBJ0lYASjKw243276 intact-crc:DFD64478F6D652B8|rigid:mBE/R1QPVaM4NCo8TVHPU49zf6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83139 uniprotkb:O83572 intact:EBI-1588907|ensemblbacteria:AAC65096|ensemblbacteria:AGN75320 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83139_trepa(display_long)|uniprotkb:TP_0101(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588916|imex:IM-9152-3104 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003834(Cytochrome c assembly protein, transmembrane region)|ensemblbacteria:AAC65096(transcript)|ensemblbacteria:AGN75320(transcript)|ensemblbacteria:TP_0101(gene)|ensemblbacteria:TPANIC_0101(gene)|go:"GO:0016020"(membrane)|go:"GO:0017004"(cytochrome complex assembly)|refseq:WP_010881550.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0101; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gEAPFQvYJYpxwJrsUSkbRvtto/Y243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:522415E5ED8D583A|rigid:RQ1+BZ4yaaThIDlwiY7zPOBL6kM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83139 uniprotkb:O83706 intact:EBI-1588907|ensemblbacteria:AAC65096|ensemblbacteria:AGN75320 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:o83139_trepa(display_long)|uniprotkb:TP_0101(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588910|imex:IM-9152-3103 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003834(Cytochrome c assembly protein, transmembrane region)|ensemblbacteria:AAC65096(transcript)|ensemblbacteria:AGN75320(transcript)|ensemblbacteria:TP_0101(gene)|ensemblbacteria:TPANIC_0101(gene)|go:"GO:0016020"(membrane)|go:"GO:0017004"(cytochrome complex assembly)|refseq:WP_010881550.1 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0101; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gEAPFQvYJYpxwJrsUSkbRvtto/Y243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:8657D9337A2B0D00|rigid:Q1Uc/zCGrhCR25AqnaHooh6KzA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O83251 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1588932|ensemblbacteria:AAC65211 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:y222_trepa(display_long)|uniprotkb:TP_0222(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588928|imex:IM-9152-3106 author score:0.741857478 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65211(transcript)|ensemblbacteria:TP_0222(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881670.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0222; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:UvpvikRVQfLJWR9g7HwQE8FO6vE243276 intact-crc:C97DBA4231BC9B99|rigid:q2y0SDTzQevTp7HjXDV3rtpvBBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83139 uniprotkb:O83887 intact:EBI-1588907|ensemblbacteria:AAC65096|ensemblbacteria:AGN75320 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83139_trepa(display_long)|uniprotkb:TP_0101(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588922|imex:IM-9152-3105 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003834(Cytochrome c assembly protein, transmembrane region)|ensemblbacteria:AAC65096(transcript)|ensemblbacteria:AGN75320(transcript)|ensemblbacteria:TP_0101(gene)|ensemblbacteria:TPANIC_0101(gene)|go:"GO:0016020"(membrane)|go:"GO:0017004"(cytochrome complex assembly)|refseq:WP_010881550.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0101; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gEAPFQvYJYpxwJrsUSkbRvtto/Y243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:99765E389EDC8664|rigid:ozQ7s5mkwQGMquvfJ+pWj88RAkg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83251 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1588932|ensemblbacteria:AAC65211 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y222_trepa(display_long)|uniprotkb:TP_0222(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588943|imex:IM-9152-3108 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65211(transcript)|ensemblbacteria:TP_0222(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881670.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0222; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:UvpvikRVQfLJWR9g7HwQE8FO6vE243276 intact-crc:D65C3D49D54B10FD|rigid:gK+S9Sv6IIxKjcZGg6HMnT92R2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83251 uniprotkb:O83572 intact:EBI-1588932|ensemblbacteria:AAC65211 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y222_trepa(display_long)|uniprotkb:TP_0222(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588937|imex:IM-9152-3107 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65211(transcript)|ensemblbacteria:TP_0222(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881670.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0222; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UvpvikRVQfLJWR9g7HwQE8FO6vE243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:9844067D781BC041|rigid:yEu+OEHchKzk6oSA/NXhaxe9lo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83434 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1588953|ensemblbacteria:AAC65406 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:sure_trepa(display_long)|uniprotkb:surE(gene name)|psi-mi:surE(display_short)|uniprotkb:Nucleoside 5'-monophosphate phosphohydrolase(gene name synonym)|uniprotkb:TP_0419(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588949|imex:IM-9152-3109 author score:0.740071903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR002828(Survival protein SurE-like phosphatase/nucleotidase)|ensemblbacteria:AAC65406(transcript)|ensemblbacteria:TP_0419(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036523|interpro:IPR030048 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0419; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:bhUtMESfVGdRIyKqhKiNXO9BNq0243276 intact-crc:2308F9EA74A6D38E|rigid:zxz/+BLNQmURbr5a0tfBGORyzkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83093 uniprotkb:O83570 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588968|imex:IM-9152-3111 author score:0.678511044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:EADBF3ADE81F419E|rigid:/9j8CoXzqyMk3ImGpLDU/SrQ9Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83093 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588959|imex:IM-9152-3110 author score:0.739811659 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 intact-crc:94B27C4DB811306A|rigid:HBKcRT+Oli1yOJTdRDNghhZd1wE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83093 uniprotkb:O83927 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588986|imex:IM-9152-3114 author score:0.225870273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:AAC86060596032E0|rigid:RAwHIYXIDdmg5JHC4JbVjy6jlXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83093 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588980|imex:IM-9152-3113 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 intact-crc:FD001D0F0F0E3BD6|rigid:9g2/1nsXWslk8l+BGcPjHF49y38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83093 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588974|imex:IM-9152-3112 author score:0.63495165 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 intact-crc:97F40CC6451DA8FC|rigid:pFhwWeQDc+2csPusciYI7WmI87c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83093 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588998|imex:IM-9152-3116 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 intact-crc:DEC945E941153F94|rigid:0fvqwIpmBDBwpxhuyD/t6P/2v2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83093 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1588992|imex:IM-9152-3115 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 intact-crc:6246B529B69CBB1E|rigid:jcry9sG/nHiwfwK6oulzJCiZi3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83093 uniprotkb:O83745 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589004|imex:IM-9152-3117 author score:0.062238911 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:5154C030EC47E5F2|rigid:VaZui92a9MXwKl4bYppobURLHPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83354 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589016|imex:IM-9152-3119 author score:0.739808023 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0334|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 intact-crc:4375A20D1CB47F0F|rigid:nXax86dY4QFU1jPnQkQqzSz+wUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83093 uniprotkb:O83954 intact:EBI-1588963|ensemblbacteria:AGN75274|ensemblbacteria:AAC65050 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83093_trepa(display_long)|uniprotkb:TP_0054(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589010|imex:IM-9152-3118 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|interpro:IPR013123(RNA 2-O ribose methyltransferase, substrate binding)|ensemblbacteria:TP_0054(gene)|ensemblbacteria:TPANIC_0054(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|ensemblbacteria:AAC65050(transcript)|ensemblbacteria:AGN75274(transcript)|refseq:WP_010881503.1|interpro:IPR029026|interpro:IPR029028|interpro:IPR029064|interpro:IPR004441(RNA methyltransferase TrmH, group 3) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0054; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dhfLdRVu55HoAh7sIcIxfgEE4Og243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:26570DAD5DD02247|rigid:lRqqhUlE22P0PR2ElOwQ5Biq6gs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83596 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589031|imex:IM-9152-3121 author score:0.508640202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:223BE375C00A6DC8|rigid:b1PR9FnvLtp52jqSmbGc6Eb4hZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83098 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589025|imex:IM-9152-3120 author score:0.522087915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:22D870DBC9C60A80|rigid:kEqpVZdEoCUEgIMdx/pWi1FBhZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83292 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589046|imex:IM-9152-3123 author score:0.387987045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 intact-crc:F4DCAE1509EBB6BF|rigid:NbwVhxks9455Re2040r1Zn06BSM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83670 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589040|imex:IM-9152-3122 author score:0.434974615 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:FD5711CCB327B187|rigid:rGXsSP+keHKSVnJXvzXOgK4IX/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83463 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589058|imex:IM-9152-3125 author score:0.327554838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:970278AB22A1E7D8|rigid:NMq7qvn6zEZvhqHUqhtJ8i9BENs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83709 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589052|imex:IM-9152-3124 author score:0.357862712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:5601EF76BD5CCB57|rigid:qCTdQF+GsU0ymbnyaOI59xiH0jA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83292 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589064|imex:IM-9152-948 author score:0.315978304 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 intact-crc:3A92873F4ED3A095|rigid:Mh6S/0R6xecPhV+VC9izTOLvtpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83877 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589076|imex:IM-9152-950 author score:0.165210779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:60EF94213141C489|rigid:Z5nKxjIYFQ3OvURKPw2y1hkOkck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83969 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589070|imex:IM-9152-949 author score:0.266077002 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:01D3CC899A1B6FAA|rigid:tvg3Z+qs3E2xL/lruIDVY1GnVE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83667 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589088|imex:IM-9152-952 author score:0.076128626 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:66ED4017EDB96696|rigid:FwKtNzNKUS5syM/nER2IJOYZWcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83292 uniprotkb:O83413 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589082|imex:IM-9152-951 author score:0.131292491 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:1242DBE29B252895|rigid:MmBdV+OZDNhMQ6JeT/Yut2mMntA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83292 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589100|imex:IM-9152-954 author score:0.017919089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 intact-crc:EC910E6EC9D44DBD|rigid:jYeY2qrfycF5KmKKFoeVJUC468Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83292 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589094|imex:IM-9152-953 author score:0.052154273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 intact-crc:6955F82B77DE51F8|rigid:sbGqszUajb92f7yTD9TXC2KiUaI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83354 uniprotkb:O83510 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589112|imex:IM-9152-956 author score:0.739114993 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0334|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:89BC1C38462F5E96|rigid:Nw93qJZU31MjUZ1hAz2zAmpKobQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83292 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1589020|ensemblbacteria:AAC65256|ensemblbacteria:AGN75479 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83292_trepa(display_long)|uniprotkb:TP_0268(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589106|imex:IM-9152-955 author score:0.014887052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65256(transcript)|ensemblbacteria:AGN75479(transcript)|ensemblbacteria:TP_0268(gene)|ensemblbacteria:TPANIC_0268(gene)|refseq:WP_010881717.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0268; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:8syEeHqLdCAII+gFqxssG6/PSZk243276 intact-crc:9294F57C24C282D0|rigid:n4UdVDw9gYE14OgWrv8hqmPxUYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83284 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589133|imex:IM-9152-959 author score:0.612186905 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0260|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:24CE4A8C6639BC71|rigid:E+cA7B4l5TjaeXyt8rfl+4gwkaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83510 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589127|imex:IM-9152-958 author score:0.618559049 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0807|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:D60E4977A63E5327|rigid:JixqogYWauviqUv7HXZ74szAkoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83047 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1582316|ensemblbacteria:AAC64999 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589121|imex:IM-9152-957 author score:0.678435014 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0001|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 intact-crc:7FD28D9E30EC0BD5|rigid:JnRsJOKRqsE59xVwWTnGVanGpns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83126 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589145|imex:IM-9152-961 author score:0.59284685 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:AA29CCF3CA4D64C4|rigid:gwJjbwA7YTD173di/51M/XR2GY8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83637 uniprotkb:O83510 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589139|imex:IM-9152-960 author score:0.605776154 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:AE62359D252DEC1F|rigid:iYLJN/SMdn9PgyBjkLnPK9KdJqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83804 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589157|imex:IM-9152-963 author score:0.400110405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:DBC3ADFDAD213C53|rigid:i1OPgnJpx+6jFqv/iHk2BKMSJWY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83510 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589151|imex:IM-9152-962 author score:0.466106969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:48E58B6E667097CF|rigid:Iz67DEWLONulXoDUqjp6B7fjZbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83877 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589175|imex:IM-9152-966 author score:0.10672963 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:A324DD41D9F65706|rigid:ktFADdyb50LbjlabBZR5actbcWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83510 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589169|imex:IM-9152-965 author score:0.228739172 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:0C605E01C938377F|rigid:gt9PyLulztvHXrsgbk6QyUi7s64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83927 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589163|imex:IM-9152-964 author score:0.260457887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:06F36293112565D6|rigid:O4VraP3fT8ukc/XkKxNfTCkXf4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83767 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589187|imex:IM-9152-968 author score:0.049142483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:192FD0B75628E36E|rigid:C3AC1oln2SdwyZVkLoNwDcY8oxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83745 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589181|imex:IM-9152-967 author score:0.05781042 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:38A1EF98FA9AEED3|rigid:+Ts+mUdsmbUVNZEVNDOrSdWY1Ko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83954 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589199|imex:IM-9152-970 author score:0.013995581 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:56AE8CF27E2998C7|rigid:cctEFg/Hr4N9/TrLsPCbbc7MPs8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83510 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589193|imex:IM-9152-969 author score:0.016849158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 intact-crc:0CFBA7CF7790DB41|rigid:AXu0jIBjY/d4j6e4KYTtzkgY+Eg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83158 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589217|imex:IM-9152-973 author score:0.626607228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:4804B3D7D8616156|rigid:9ZeSy34FlZVaKGgKIzQyNYN452g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83158 uniprotkb:O83158 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589211|imex:IM-9152-972 author score:0.736763889 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:C06A8A9DBD6E328C|rigid:/Ygd0gP7B9SWnrOjEuxzYypYVlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83510 uniprotkb:O83958 intact:EBI-1589116|ensemblbacteria:AAC65484|ensemblbacteria:AGN75687 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83510_trepa(display_long)|uniprotkb:mreB(gene name)|psi-mi:mreB(display_short)|uniprotkb:TP_0497(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589205|imex:IM-9152-971 author score:0.002173504 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|ensemblbacteria:AAC65484(transcript)|ensemblbacteria:AGN75687(transcript)|ensemblbacteria:TP_0497(gene)|ensemblbacteria:TPANIC_0497(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|refseq:WP_010881946.1|interpro:IPR004753(Cell shape determining protein MreB/Mrl) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0497; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MuDPDhJoDymCTB3idUC/evFXp5c243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7633C23494012437|rigid:qWn5cMJeI+Z/UVeiCK7SJiO+Zyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83158 uniprotkb:O83312 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589229|imex:IM-9152-975 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:1C1326B513AF71F1|rigid:Crr2OsZz2Z8/fN/F25H4i0uAjNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83158 uniprotkb:O83970 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589223|imex:IM-9152-974 author score:0.508270364 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:A2A58DEEE1866CC3|rigid:M61M/N8NJZPnCXzEiWieztUVoaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83158 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589241|imex:IM-9152-977 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:A32CB955AC2BE40A|rigid:j7de53neuEofsELN1u5fDjxQL0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83158 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589235|imex:IM-9152-976 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0121; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:9BE6A1E7EDE513C7|rigid:OHCiaYsN2+X+vy28aBQiucAx9Rs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83348 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589253|imex:IM-9152-979 author score:0.67424575 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:6099ADA1005F37D5|rigid:0wRQkskZ5gxLoamSpJO5hsYyQbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83348 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589247|imex:IM-9152-978 author score:0.736713598 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:EE09241D4D689CA7|rigid:Ml15RbL1toVLPv5vXnfzlKptLaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83348 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589265|imex:IM-9152-981 author score:0.624659376 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:68F05CC3BA28F1CD|rigid:cAaNV3Cf/CbJmG0X6JhwmauD9m0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83348 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589259|imex:IM-9152-980 author score:0.637196683 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:D0B534E19872D02D|rigid:HlkKyN0WKVy7Z8ebCNk7dEOodVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83348 uniprotkb:O83877 intact:EBI-1585449|ensemblbacteria:AAC65315 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589283|imex:IM-9152-984 author score:0.119790274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B6FCC2184A1AA8BA|rigid:tAfSFR7Pdy2qQ4DKQb5BBz02HKo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83348 uniprotkb:O83099 intact:EBI-1585449|ensemblbacteria:AAC65315 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589277|imex:IM-9152-983 author score:0.243626594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:1A33884FCD141D8D|rigid:yqZ1Mc0/Y5XO83sQCJceMWzp/MU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83348 uniprotkb:O83565 intact:EBI-1585449|ensemblbacteria:AAC65315 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589271|imex:IM-9152-982 author score:0.519643121 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:7ACC7E1FC5EBBE1A|rigid:CsLKJdSznumeA5oEiI0l9oDPLL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83348 uniprotkb:O83745 intact:EBI-1585449|ensemblbacteria:AAC65315 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589295|imex:IM-9152-986 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:EFE69902A8CF7EBC|rigid:7velP2VGaoTzJjEPB4bamzYReyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83348 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589289|imex:IM-9152-985 author score:0.101298891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:C5973DA4B8F13B4E|rigid:F+19VsE5+fRFuvBsOo+9aFmFkzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83348 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1585449|ensemblbacteria:AAC65315 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:muts_trepa(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:TP_0328(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589301|imex:IM-9152-987 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|ensemblbacteria:AAC65315(transcript)|ensemblbacteria:TP_0328(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0003684"(damaged DNA binding)|refseq:WP_010881776.1|interpro:IPR027417|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR036187|interpro:IPR036678 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0328; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:qgrPmR0kKIjdtgW0ae+9Ue8e/qk243276 intact-crc:920DCCF1D4A71B04|rigid:09qOOdgbE4XNRRSslJUXN91iJ+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83048 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1198595|intact:EBI-1583590|ensemblbacteria:AAC65000 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:dpo3b_trepa(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:DNA polymerase III subunit beta(gene name synonym)|uniprotkb:TP_0002(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589316|imex:IM-9152-989 author score:0.661816723 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022635|interpro:IPR022637|interpro:IPR022634|refseq:WP_010881452.1|ensemblbacteria:AAC65000(transcript)|ensemblbacteria:TP_0002(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0002|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:4FZeat7yhkrv79CgJ0/2soG7qD4243276 intact-crc:9E7BA231924F5FC0|rigid:vOOQ7H1tqMsY0CJEUjt19fxVRxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O07885 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589310|imex:IM-9152-988 author score:0.736313804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 intact-crc:7480B939697A2778|rigid:Qw+0FNMRc7ZV+WwtT8iZ44yvn8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83665 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589322|imex:IM-9152-990 author score:0.601844756 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:D5ECC7E1FA770F5D|rigid:zlhsn9R3q88cU4bT8PESqxYN+Og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83665 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589334|imex:IM-9152-992 author score:0.445951745 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:AA3E54A532F59F2C|rigid:ausMkRT3Lo5mxQlhYT0fhSD4TeY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83195 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589328|imex:IM-9152-991 author score:0.592727782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:63830AC34DE17723|rigid:WQUTmFjCcQ4qiFxrtmlIVqgjLlA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83574 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589346|imex:IM-9152-994 author score:0.151266804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:8B1620DF78BD5330|rigid:XhQvl7HF5aoNaAgIjyk3rj0xHV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83969 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589340|imex:IM-9152-993 author score:0.229140169 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:CA465A6B839C3049|rigid:1PmrkrBpcbDipeHsx6si6+TLa2Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83665 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589358|imex:IM-9152-996 author score:0.118293717 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:51BA7921CA85A451|rigid:639Sw8R4AW2GZ78WD/ZyrSAL98o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83665 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589352|imex:IM-9152-995 author score:0.125599902 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:08392ADA1958146B|rigid:Wp2GBdpwErcnVgWCKxm4wG9+l6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83665 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589376|imex:IM-9152-999 author score:0.016840989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:C77F05312FA76259|rigid:MJFsTPpdPCr04rtZbGmFlEAFGWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83282 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589370|imex:IM-9152-998 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:A4309056A2ECB1A9|rigid:nbhjX7qNR4cRb/uhyHuCIdIkbNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83665 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589364|imex:IM-9152-997 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 intact-crc:30EFC96A495F08C5|rigid:UfbLgVn8hOQZO3d+G0B92uLKbp0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83304 uniprotkb:O83960 intact:EBI-1589392|ensemblbacteria:AAC65277 intact:EBI-1583870|ensemblbacteria:AAC26583 psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:o83960_trepa(display_long)|uniprotkb:TP_0995(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589388|imex:IM-9152-1001 author score:0.735051743 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC26583(transcript)|ensemblbacteria:TP_0995(gene)|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0995|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 rogid:e/7IeUNCDYEoLFDH9to3t6L3g3E243276 intact-crc:CB73BDC33AB06A49|rigid:mCHuYXb+8rkRot4yhjAVVYLbPTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83665 uniprotkb:O83958 intact:EBI-1198581|intact:EBI-1589307|ensemblbacteria:AAC65633|ensemblbacteria:AGN75837 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83665_trepa(display_long)|uniprotkb:TP_0659(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589382|imex:IM-9152-1000 author score:0.002972012 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013384(Flagellar hook-associated protein 3)|interpro:IPR001029(Flagellin, C-terminal)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882104.1|ensemblbacteria:AAC65633(transcript)|ensemblbacteria:AGN75837(transcript)|ensemblbacteria:TP_0659(gene)|ensemblbacteria:TPANIC_0659(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0659; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4YRdKOiHX2csErOSBFsBhthwzf8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:FCF094EBBE47733F|rigid:Y0pw+P83vFDZbSs2NcLt/n1F3pA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83304 uniprotkb:O83098 intact:EBI-1589392|ensemblbacteria:AAC65277 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589403|imex:IM-9152-1003 author score:0.643284085 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:46759B59E3290435|rigid:Yj4ncFA+nO+TCWe/HooVas8prE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83304 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1589392|ensemblbacteria:AAC65277 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589397|imex:IM-9152-1002 author score:0.691048678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 intact-crc:482E614C6558775B|rigid:HvpW6Hu+KaB7tzDK+wNeHT5Rtdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83304 uniprotkb:O83398 intact:EBI-1589392|ensemblbacteria:AAC65277 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589415|imex:IM-9152-1005 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:2B668D88B8F8A3C7|rigid:aLeGL5GOBGYrFqH2g/LAH2kJXnA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83304 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1589392|ensemblbacteria:AAC65277 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589409|imex:IM-9152-1004 author score:0.605422711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 intact-crc:2DCC66EC80AD5DEF|rigid:EhoFyzTOhGlEPm08FZo3/k6eGI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83304 uniprotkb:O83982 intact:EBI-1589392|ensemblbacteria:AAC65277 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589421|imex:IM-9152-1006 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:C4E1C9F31B4E1B86|rigid:QXHGHa3GDotHC9h3nmiHfw21FIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83207 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1589433|ensemblbacteria:AAC65167 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:y177_trepa(display_long)|uniprotkb:TP_0177(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589436|imex:IM-9152-1008 author score:0.734859573 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR002826(Protein of unknown function DUF115)|ensemblbacteria:AAC65167(transcript)|ensemblbacteria:TP_0177(gene)|refseq:WP_010881624.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0177; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:3shVxHP2/lmq91hsOLVmAvH9Zuc243276 intact-crc:AF1ABEE248AD64BC|rigid:slAp4T1dJvOKOOH7l6/R1/P5IMQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83304 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1589392|ensemblbacteria:AAC65277 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y280_trepa(display_long)|uniprotkb:TP_0280(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589427|imex:IM-9152-1007 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65277(transcript)|ensemblbacteria:TP_0280(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0280; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:hBCVF7LSeTJZre2RqNbREMsmU6E243276 intact-crc:04F55A203F2548CD|rigid:pUXE7mS3T8K3mteU2bSP53AI3gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83813 uniprotkb:O83542 intact:EBI-1589455|ensemblbacteria:AAC65807|ensemblbacteria:AGN76011 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83813_trepa(display_long)|uniprotkb:TP_0841(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589451|imex:IM-9152-1010 author score:0.734859573 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011782(Peptidase S1C, Do)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65807(transcript)|ensemblbacteria:AGN76011(transcript)|ensemblbacteria:TP_0841(gene)|ensemblbacteria:TPANIC_0841(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034|interpro:IPR041489 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0841; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aibtgooGgvb7pONexV7PiEtIq1w243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:1BC03A60B2007E29|rigid:QOxRVNMXRRvjPv96yDduO6syurQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83492 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1589446|ensemblbacteria:AAC65468|ensemblbacteria:AGN75671 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83492_trepa(display_long)|uniprotkb:TP_0479(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589442|imex:IM-9152-1009 author score:0.734859573 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR024471|ensemblbacteria:AAC65468(transcript)|ensemblbacteria:AGN75671(transcript)|ensemblbacteria:TP_0479(gene)|ensemblbacteria:TPANIC_0479(gene)|refseq:WP_010881928.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0479; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:iI5yQmdxPyDG/3EhEBbezW3/SiQ243276 intact-crc:58C62ED9F88AC7C2|rigid:S1xjz7AXvxNvpFOv5iJiS6pNwaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83433 uniprotkb:O83119 intact:EBI-1589464|ensemblbacteria:AAC65405 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589469|imex:IM-9152-1012 author score:0.663675566 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:129B08DE8141F97B|rigid:3lvl2SdPYoreNyPeMcsTvRslOeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83433 uniprotkb:Q08255 intact:EBI-1589464|ensemblbacteria:AAC65405 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589460|imex:IM-9152-1011 author score:0.734273438 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:28E55A5925CCAF2C|rigid:wiMSA+u+2X6kExklxRP6gtXR3l4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83433 uniprotkb:O83738 intact:EBI-1589464|ensemblbacteria:AAC65405 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589487|imex:IM-9152-1015 author score:0.51512044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:083016BFC3B5C648|rigid:9sgorRf7Rh6zPmTzfg0Siad/BYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83433 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1589464|ensemblbacteria:AAC65405 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589481|imex:IM-9152-1014 author score:0.626722629 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 intact-crc:2C280474CAAF057D|rigid:19d9VpDsVPzSATVTbxGmZuun3BQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83433 uniprotkb:O83133 intact:EBI-1589464|ensemblbacteria:AAC65405 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589475|imex:IM-9152-1013 author score:0.651552908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:C8492503FE4F55F3|rigid:CpNiJukXHmJr8l64cIsRWHnnd08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83433 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1589464|ensemblbacteria:AAC65405 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589499|imex:IM-9152-1017 author score:0.126555569 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 intact-crc:CE6E78BF4A590788|rigid:y5Iu1RKoaM+9twvXastOrJYzYaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83433 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1589464|ensemblbacteria:AAC65405 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589493|imex:IM-9152-1016 author score:0.448007483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 intact-crc:A8688B253C17C7D4|rigid:fDGk2A929wrjfL0QfRqKEfR0nd0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83433 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1589464|ensemblbacteria:AAC65405 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589511|imex:IM-9152-1019 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 intact-crc:338F3844CFC88345|rigid:EdJ7n1xON3llABTMCemcArYu6mA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83433 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1589464|ensemblbacteria:AAC65405 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:gal1_trepa(display_long)|uniprotkb:galK(gene name)|psi-mi:galK(display_short)|uniprotkb:Galactose kinase(gene name synonym)|uniprotkb:TP_0418(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589505|imex:IM-9152-1018 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR000705(Galactokinase)|interpro:IPR019539|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65405(transcript)|ensemblbacteria:TP_0418(gene)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0418; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ywupGeyZhrs9eQJpqovx10qlqpY243276 intact-crc:613EEBDA930AABB7|rigid:LGqTNtB+GmXgL+OF+0zzrxGO1zo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83244 uniprotkb:O83613 intact:EBI-1589531|ensemblbacteria:AAC65210 intact:EBI-1589517|ensemblbacteria:AAC65577 psi-mi:y214_trepa(display_long)|uniprotkb:TP_0214(locus name) psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589527|imex:IM-9152-1021 author score:0.726286851 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65210(transcript)|ensemblbacteria:TP_0214(gene)|refseq:WP_010881662.1 interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0214|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HAC6HFUlZSuAKwcd7O49uTZBi/M243276 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 intact-crc:B7EC09DE7964161C|rigid:f9KzlR7RBnf9w/eLMKUSOL+mJgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83750 uniprotkb:O83613 intact:EBI-1585511|ensemblbacteria:AAC65739|ensemblbacteria:AGN75944 intact:EBI-1589517|ensemblbacteria:AAC65577 psi-mi:o83750_trepa(display_long)|uniprotkb:TP_0771(locus name) psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589521|imex:IM-9152-1020 author score:0.731606157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003841(Na+/Pi-cotransporter)|interpro:IPR004633(Na/Pi cotransporter II-related)|interpro:IPR030147|ensemblbacteria:AAC65739(transcript)|ensemblbacteria:AGN75944(transcript)|ensemblbacteria:TP_0771(gene)|ensemblbacteria:TPANIC_0771(gene)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0015114"(phosphate ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044341"(sodium-dependent phosphate transport)|interpro:IPR038078 interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0771|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hsOxDOX11Gb+UEPi+g0mxPF1C9U243276 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 intact-crc:535E6CE6F3A3DF01|rigid:v9BSrDjNkGLCmwInUvsoQa1SPWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83613 uniprotkb:O83463 intact:EBI-1589517|ensemblbacteria:AAC65577 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589542|imex:IM-9152-1023 author score:0.414999124 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:B1D8E15789D46D71|rigid:zJrixIHZ4qUY0V+tWjbYGz5ITrQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83613 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1589517|ensemblbacteria:AAC65577 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589536|imex:IM-9152-1022 author score:0.510579206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 intact-crc:FC5C248CFA7F6C17|rigid:Gdku6HgkDge5VKmVHj5srVRL6tA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83613 uniprotkb:O83574 intact:EBI-1589517|ensemblbacteria:AAC65577 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589554|imex:IM-9152-1025 author score:0.186323126 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C196E28F1C206D02|rigid:LN+C4631pqwEjuR02DniP8gWg5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83613 uniprotkb:O83312 intact:EBI-1589517|ensemblbacteria:AAC65577 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589548|imex:IM-9152-1024 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:8D428732F5524988|rigid:luL2qit8CBJTUn9ASaVSHN1Yaxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83613 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1589517|ensemblbacteria:AAC65577 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589566|imex:IM-9152-1027 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 intact-crc:2BB0DCC5237B67C7|rigid:/fdnhRs9VrsIbcrvuOjvJmre5yU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83613 uniprotkb:O83413 intact:EBI-1589517|ensemblbacteria:AAC65577 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589560|imex:IM-9152-1026 author score:0.168869005 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:EE4F38E8786A21B9|rigid:ZdM7YwHsKPvAWdxYVdUL0cvzXKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83479 uniprotkb:O83275 intact:EBI-1589582|ensemblbacteria:AAC65459 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:y466_trepa(display_long)|uniprotkb:TP_0466(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589578|imex:IM-9152-1029 author score:0.729580914 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65459(transcript)|ensemblbacteria:TP_0466(gene)|refseq:WP_010881915.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0466; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:y1iiulYZIbNFyc8U4I19gvOenU0243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:E656EFDD5DAC1D53|rigid:JDxqSyWrVijwoE078dJ5vo6arzk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83613 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589517|ensemblbacteria:AAC65577 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rrf_trepa(display_long)|uniprotkb:frr(gene name)|psi-mi:frr(display_short)|uniprotkb:Ribosome-releasing factor(gene name synonym)|uniprotkb:TP_0604(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589572|imex:IM-9152-1028 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR002661(Ribosome recycling factor)|interpro:IPR023584|ensemblbacteria:AAC65577(transcript)|ensemblbacteria:TP_0604(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006415"(translational termination)|refseq:WP_010882050.1|interpro:IPR036191 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0604; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:9//E9UN7R8ce0sEy/NKzs+P3X5s243276 intact-crc:B662C810F90BDB9C|rigid:+LTzkEemXCnl3GTpztmWXBvhBjU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O07887 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1589587|ensemblbacteria:AAC65689 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:motb_trepa(display_long)|uniprotkb:motB(gene name)|psi-mi:motB(display_short)|uniprotkb:Chemotaxis protein MotB(gene name synonym)|uniprotkb:TP_0724(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589597|imex:IM-9152-1031 author score:0.615895006 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|ensemblbacteria:AAC65689(transcript)|ensemblbacteria:TP_0724(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility)|interpro:IPR025713|interpro:IPR036737|refseq:WP_010882169.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0724; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:Ep44CJUi8fTnDPc9cJKAK3pdyzg243276 intact-crc:E85A694AC6F17179|rigid:lr3Ao1/KvUrbgMfQzmCyQt1Hw6o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07887 uniprotkb:O83927 intact:EBI-1589587|ensemblbacteria:AAC65689 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:motb_trepa(display_long)|uniprotkb:motB(gene name)|psi-mi:motB(display_short)|uniprotkb:Chemotaxis protein MotB(gene name synonym)|uniprotkb:TP_0724(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589591|imex:IM-9152-1030 author score:0.729456036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|ensemblbacteria:AAC65689(transcript)|ensemblbacteria:TP_0724(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097588"(archaeal or bacterial-type flagellum-dependent cell motility)|interpro:IPR025713|interpro:IPR036737|refseq:WP_010882169.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0724; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ep44CJUi8fTnDPc9cJKAK3pdyzg243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:FFB9B48439E6CD60|rigid:rwpTVGwFAmqOBenFeJ2vp90yb3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83830 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1589603|ensemblbacteria:AAC65829 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:y858_trepa(display_long)|uniprotkb:TP_0858(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589612|imex:IM-9152-1033 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65829(transcript)|ensemblbacteria:TP_0858(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0858; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:YJrHSxW1qB5XRK9VQxMS1/mkgn4243276 intact-crc:A74B94F68F73767C|rigid:C9RXoul2lUO13+bC9WunVkWs26w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83830 uniprotkb:P45685 intact:EBI-1589603|ensemblbacteria:AAC65829 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:y858_trepa(display_long)|uniprotkb:TP_0858(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589606|imex:IM-9152-1032 author score:0.727839306 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65829(transcript)|ensemblbacteria:TP_0858(gene) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0858; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YJrHSxW1qB5XRK9VQxMS1/mkgn4243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:44317627944F5AE6|rigid:2wv2rLGzfsHGvchTNSowvOjLX6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83681 uniprotkb:O06690 intact:EBI-1198521|intact:EBI-1586987|ensemblbacteria:AAC65651 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 psi-mi:y675_trepa(display_long)|uniprotkb:TP_0675(locus name) psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589621|imex:IM-9152-1034 author score:0.726286851 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002816(Pheromone shutdown-related, TraB)|refseq:WP_010882120.1|ensemblbacteria:AAC65651(transcript)|ensemblbacteria:TP_0675(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0675|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2TmSwpa+jeHRVL+79cLSlWwNcyg243276 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 intact-crc:F4D03731044BFDB9|rigid:fEz0m7GKbLW0jfWVqxVCf1sanUE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O06690 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589633|imex:IM-9152-1036 author score:0.663675566 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 intact-crc:77DB04D2A37583A1|rigid:PL46f+fHq08OkboKEgCFlj+MAbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06690 uniprotkb:O83436 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589627|imex:IM-9152-1035 author score:0.715453401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0421|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:0DC99B01B36462A1|rigid:L79TdcXMAJvZy9ei8ptr86KGhEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O06690 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589645|imex:IM-9152-1038 author score:0.428128243 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 intact-crc:367545D2E182C0FF|rigid:Dlt7bEZt8bWepn5JV2IkciJJ6sI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06690 uniprotkb:O83804 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589639|imex:IM-9152-1037 author score:0.508393644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:19638287DB04C0D1|rigid:q1WiPGqC5xgZQwnTiu8rwDM+QNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06690 uniprotkb:O83282 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589657|imex:IM-9152-1040 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:B4DECDA7F1BAC954|rigid:NDCKxN3Rc2QHo6c1NBeQ/olzoW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06690 uniprotkb:P21992 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589651|imex:IM-9152-1039 author score:0.250271228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:B2591D77B4E1519B|rigid:5P9YZaAjqD6VNssgpX+01m/HMaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06690 uniprotkb:O83958 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589669|imex:IM-9152-1042 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BD212BD626459888|rigid:KMcqIF5J1txwr2+MLa/so2C0qko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O06690 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198505|intact:EBI-1589618|ensemblbacteria:AAC65541|ensemblbacteria:AGN75754 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o06690_trepa(display_long)|uniprotkb:TP_0567(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589663|imex:IM-9152-1041 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65541(transcript)|ensemblbacteria:AGN75754(transcript)|ensemblbacteria:TP_0567(gene)|ensemblbacteria:TPANIC_0567(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0567; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:88/0WMC3WD2cQ8THhg32cEPx4+A243276 intact-crc:83296EB87A2ADDAC|rigid:RKErsGmXVhapRLiGfvdv1fmR5VM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83607 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1588862|ensemblbacteria:AAC65581 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y598_trepa(display_long)|uniprotkb:TP_0598(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589681|imex:IM-9152-1044 author score:0.333073726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblbacteria:AAC65581(transcript)|ensemblbacteria:TP_0598(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0598; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:36a9BGsnoVqLEXf5W9sWbYfBS60243276 intact-crc:E3958892DE1304A3|rigid:iLCt+Yu1un3HdmdYv05uRSqjLu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83607 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1588862|ensemblbacteria:AAC65581 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:y598_trepa(display_long)|uniprotkb:TP_0598(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589675|imex:IM-9152-1043 author score:0.726090693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblbacteria:AAC65581(transcript)|ensemblbacteria:TP_0598(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0598; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:36a9BGsnoVqLEXf5W9sWbYfBS60243276 intact-crc:07FFF13628841E4E|rigid:GbDNknaQy9Rf4fPHQITvUREwPKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83776 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589693|imex:IM-9152-1046 author score:0.724675151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:39671A2C0CB823D9|rigid:PCj4hehiNyNx3PhI9vvPrXG7wvM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83607 uniprotkb:O83574 intact:EBI-1588862|ensemblbacteria:AAC65581 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y598_trepa(display_long)|uniprotkb:TP_0598(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589687|imex:IM-9152-1045 author score:0.250086168 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblbacteria:AAC65581(transcript)|ensemblbacteria:TP_0598(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0598; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:36a9BGsnoVqLEXf5W9sWbYfBS60243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:4BCD39E1154D6778|rigid:XnIjE1VgV0B3G3FHm2Iu/VUSNkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83398 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589708|imex:IM-9152-1048 author score:0.357056648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:A6D2D4D02169DB50|rigid:3s/JKZfCInxX37F75QXpUtCG2wg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83957 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1589703|ensemblbacteria:AAC65948|ensemblbacteria:AGN76156 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83957_trepa(display_long)|uniprotkb:TP_0992(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589699|imex:IM-9152-1047 author score:0.693136259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 ensemblbacteria:AAC65948(transcript)|ensemblbacteria:AGN76156(transcript)|ensemblbacteria:TP_0992(gene)|ensemblbacteria:TPANIC_0992(gene)|refseq:WP_010882436.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0992|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:EIrFAyXg8Dt2Z/CS5ZukQWliPWI243276 intact-crc:0364394D9A4BA9BC|rigid:pydC9E+ifqsD/UUbQb3yHQLbWtA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83531 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589720|imex:IM-9152-1050 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:BE261C990A10D43B|rigid:RcTROo/ELvOTSZoEbKPyCKX30P0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83776 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589714|imex:IM-9152-1049 author score:0.292909869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:463940210C5C758E|rigid:gRsYe/fOINKJZ3lXsfk4QevnTGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83312 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589732|imex:IM-9152-1052 author score:0.225956533 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:4226AC242E125348|rigid:qqwGpWS09OqSw50ilft0VGBtCm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83776 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589726|imex:IM-9152-1051 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:1FCA3839FF81713E|rigid:Sdk5oUjX1JnDeSjQZNU2WoBvnUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83745 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589744|imex:IM-9152-1054 author score:0.052129895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:FBA9B5A571134B31|rigid:TCeBRCLvimGcGk/iSzSJH2NfnOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83776 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589738|imex:IM-9152-1053 author score:0.097315309 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:1B5BD9C75D35B28C|rigid:1HFRBCffeJZHP3Zu1EFjJR2Lysg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83954 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589756|imex:IM-9152-1056 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:D2E6619A6CCEADD8|rigid:RHad8Xokk1HN/lgpvj6D+I1Byt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83776 uniprotkb:O83282 intact:EBI-1584004|ensemblbacteria:AAC65761 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589750|imex:IM-9152-1055 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:ED2212F8735BBDD6|rigid:jgr+p7PaLeRzjShTLpwiGX9ViXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83171 uniprotkb:O83931 intact:EBI-1589772|ensemblbacteria:AAC65126 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:y135_trepa(display_long)|uniprotkb:TP_0135(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589768|imex:IM-9152-1058 author score:0.7243351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65126(transcript)|ensemblbacteria:TP_0135(gene) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0135; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXSM2glkSKt4uwOetpO+aNWlHoo243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:5549ECD044258A1C|rigid:IzK8tx2jQvxQDx/tEKIFgKKxdWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83776 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584004|ensemblbacteria:AAC65761 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:sym_trepa(display_long)|uniprotkb:metG(gene name)|psi-mi:metG(display_short)|uniprotkb:metS(gene name synonym)|uniprotkb:TP_0798(locus name)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589762|imex:IM-9152-1057 author score:0.002098604 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR033911|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR023458|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002547(tRNA-binding region)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65761(transcript)|ensemblbacteria:TP_0798(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882243.1|interpro:IPR029038|interpro:IPR041872 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0798; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:TTOMD2YpjOQK3JT1ZdYp2DTm5W0243276 intact-crc:317A85E7CF8AA7BB|rigid:l1jJW11CgFIBZM3Riq+ZWppVzRY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83171 uniprotkb:O83745 intact:EBI-1589772|ensemblbacteria:AAC65126 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y135_trepa(display_long)|uniprotkb:TP_0135(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589783|imex:IM-9152-1060 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65126(transcript)|ensemblbacteria:TP_0135(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0135; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXSM2glkSKt4uwOetpO+aNWlHoo243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:4B8B462DB4B5B19E|rigid:kmgOWCvRyaie4sWx5ZN9fuvWt28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83171 uniprotkb:O83413 intact:EBI-1589772|ensemblbacteria:AAC65126 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y135_trepa(display_long)|uniprotkb:TP_0135(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589777|imex:IM-9152-1059 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65126(transcript)|ensemblbacteria:TP_0135(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0135; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXSM2glkSKt4uwOetpO+aNWlHoo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CFE7FDA3CD078D75|rigid:f0lHtEtPIFHr5N6C/JJZXG1b/Og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83264 uniprotkb:O83865 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589798|imex:IM-9152-1062 author score:0.722671423 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0236|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:52E3C74C0D267297|rigid:ahxHLiCklJfgwdRVgDAXaPtzwys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83171 uniprotkb:O83958 intact:EBI-1589772|ensemblbacteria:AAC65126 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y135_trepa(display_long)|uniprotkb:TP_0135(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589789|imex:IM-9152-1061 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65126(transcript)|ensemblbacteria:TP_0135(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0135; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VXSM2glkSKt4uwOetpO+aNWlHoo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B853FA9370882E71|rigid:Luv8gvCDBtopAllcCO1/O+7gg1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83865 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589810|imex:IM-9152-1409 author score:0.272759532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:C555EED92E069583|rigid:BfZ/jh9BHbCvVOcTzFdaUSp13NA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83865 uniprotkb:O83261 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589804|imex:IM-9152-1408 author score:0.677514296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:2CFF4060378406BD|rigid:KCDSdXj26lYCEh/L878glCyjRpQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83865 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589822|imex:IM-9152-1411 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:79A334BEFE4162B3|rigid:/6ChTEvkj0c4kmFH/ij4prCvrXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83865 uniprotkb:O83927 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589816|imex:IM-9152-1410 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:325B91452F8DDB76|rigid:qf8b11Ul/4GtRvMp5mbBXuu8lKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83865 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589828|imex:IM-9152-1412 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:3D39BDA7EB11CBA4|rigid:Aifs6Mkb40Zz042RUPKJZ+agPHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83382 uniprotkb:O83751 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589849|imex:IM-9152-1415 author score:0.720902339 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0772|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 intact-crc:95853B6C0422A31D|rigid:HP6m257LqF0b51XjkslN6qxtNNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83865 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589840|imex:IM-9152-1414 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:94BB54875D6D23C2|rigid:ecImZ/MVvFnRB44WUi8GQbYM6mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83865 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589834|imex:IM-9152-1413 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0895; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:B08F34550D339786|rigid:lCzGpO9Au6GZ5XCwvlosA4WxJhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83382 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589861|imex:IM-9152-1417 author score:0.681458933 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 intact-crc:0A8968D4DE9E90C7|rigid:bR5vUMAGHtyXhwrW+O0ebk5spn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83382 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589855|imex:IM-9152-1416 author score:0.693031334 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 intact-crc:AF295227A71EF4FD|rigid:duJaBd3F528dJknMcReu79x5tZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83382 uniprotkb:O83804 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589873|imex:IM-9152-1419 author score:0.508393644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:4D6E5E856748045D|rigid:XKpPS2g+mDkeTFKOL0KcRLp62FQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83382 uniprotkb:O83105 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589867|imex:IM-9152-1418 author score:0.675586465 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:C49C6E7E54C3AAEA|rigid:9JfJ98j5NAbW+ypB2Mt9agQ2+gw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83382 uniprotkb:P21992 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589885|imex:IM-9152-1421 author score:0.250271228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:E654C17508AD9517|rigid:kgkS6Raxw3nWc5lguvQPN2MWBPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83382 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589879|imex:IM-9152-1420 author score:0.32119506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 intact-crc:6B0E62C699FDA5BA|rigid:Z/lqa+Cju9JOgnUB5+g96O3NoPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83382 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589897|imex:IM-9152-1423 author score:0.084778374 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 intact-crc:9B4DC7E07694ADA8|rigid:9+HK3oSeM/aTV++GC4fZkbnEJ2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83382 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1589846|ensemblbacteria:AAC65355|ensemblbacteria:AGN75564 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83382_trepa(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TP_0367(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589891|imex:IM-9152-1422 author score:0.225870273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|ensemblbacteria:AAC65355(transcript)|ensemblbacteria:AGN75564(transcript)|ensemblbacteria:TP_0367(gene)|ensemblbacteria:TPANIC_0367(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|interpro:IPR011890(Chromosome segregation protein SMC)|refseq:WP_010881815.1|interpro:IPR027417|interpro:IPR024704 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0367; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:wHWE4GKSQ8f68kc/6Kp5to0o0e4243276 intact-crc:769560D683080A93|rigid:zJlpxrSeFOPA/fTQVgBI3MB1aqs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83406 uniprotkb:P16055 intact:EBI-1589907|ensemblbacteria:AAC65375|ensemblbacteria:AGN75585 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:o83406_trepa(display_long)|uniprotkb:TP_0391(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589903|imex:IM-9152-1424 author score:0.720703806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR004107(Integrase, N-terminal SAM-like, phage)|ensemblbacteria:AAC65375(transcript)|ensemblbacteria:AGN75585(transcript)|ensemblbacteria:TP_0391(gene)|ensemblbacteria:TPANIC_0391(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0015074"(DNA integration)|refseq:WP_010881839.1|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR044068 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0391; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Gn1GNsX0WgpKrm31gOVgQr+atJY243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:DE8AF010C22C3BD4|rigid:nVhO1JIZOSnCsur9SyDElKm7V0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83406 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1589907|ensemblbacteria:AAC65375|ensemblbacteria:AGN75585 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83406_trepa(display_long)|uniprotkb:TP_0391(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589918|imex:IM-9152-1426 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR004107(Integrase, N-terminal SAM-like, phage)|ensemblbacteria:AAC65375(transcript)|ensemblbacteria:AGN75585(transcript)|ensemblbacteria:TP_0391(gene)|ensemblbacteria:TPANIC_0391(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0015074"(DNA integration)|refseq:WP_010881839.1|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR044068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0391; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Gn1GNsX0WgpKrm31gOVgQr+atJY243276 intact-crc:1B06DF7B52693F77|rigid:8TYI7tRhByVK2MHttUqXBdNSGxQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83406 uniprotkb:O83767 intact:EBI-1589907|ensemblbacteria:AAC65375|ensemblbacteria:AGN75585 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83406_trepa(display_long)|uniprotkb:TP_0391(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589912|imex:IM-9152-1425 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR004107(Integrase, N-terminal SAM-like, phage)|ensemblbacteria:AAC65375(transcript)|ensemblbacteria:AGN75585(transcript)|ensemblbacteria:TP_0391(gene)|ensemblbacteria:TPANIC_0391(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0015074"(DNA integration)|refseq:WP_010881839.1|interpro:IPR010998(Integrase, Lamba-type, N-terminal)|interpro:IPR044068 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0391; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Gn1GNsX0WgpKrm31gOVgQr+atJY243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:FF6C636851F764FE|rigid:m2U4SMigM/eeEEVE8uK/93qybP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83061 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589924|imex:IM-9152-1427 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0017|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 intact-crc:A1BFCC2F9C43012A|rigid:Kez74mY23OJkjNUKn5C1yTyu6b0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83793 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1584868|ensemblbacteria:AAC65788 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:y818_trepa(display_long)|uniprotkb:TP_0818(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589933|imex:IM-9152-1428 author score:0.713656517 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) ensemblbacteria:AAC65788(transcript)|ensemblbacteria:TP_0818(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0818|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:QnxKmMr04H37/A461aRYWlKKgdE243276 intact-crc:257E564511ECEEBB|rigid:S9jcojt4wmjUlDqwepkbNjxNODM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83751 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589945|imex:IM-9152-1430 author score:0.702527915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0795|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 intact-crc:90EE3D0234D79A38|rigid:p7gTo9picEyPDTz9RG9cOYxMcn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83699 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1586728|ensemblbacteria:AAC65670 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:rpoz_trepa(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:TP_0701(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589939|imex:IM-9152-1429 author score:0.708123392 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR006110(RNA polymerase Rpb6)|ensemblbacteria:AAC65670(transcript)|ensemblbacteria:TP_0701(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|refseq:WP_010882146.1|interpro:IPR036161 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0701|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:qImQ7fWBJEGqpSutHzSZ0CANeg0243276 intact-crc:D2FE469028C6AF9C|rigid:2whHdbH4Jg7b8/B38nrWs3LeXrg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83751 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589963|imex:IM-9152-1433 author score:0.319518858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 intact-crc:E75F1F8132AFCB8A|rigid:YK+/xIhtgDqMmxhb5hxgKwUDJHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83411 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589957|imex:IM-9152-1432 author score:0.637196683 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 intact-crc:7507AB01D7543CD0|rigid:GktV4YHA13WBfYcBJ9N3MUyNMj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83354 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589951|imex:IM-9152-1431 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0334|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 intact-crc:30BEC03CFE0E87E5|rigid:80gSW2g5YBw0HYRo/vp/zbT2rbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83751 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589969|imex:IM-9152-1434 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 intact-crc:24CF4EEA25D5B0FE|rigid:5SayYbj8EHPbP6VoxSx2zQsQKXI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83751 uniprotkb:O83745 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589981|imex:IM-9152-1436 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:BD6F253D06B5B5EA|rigid:uyy0fn8/WMXTaVFF9L1am3Nj+xI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83751 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198765|intact:EBI-1585229|ensemblbacteria:AAC65742 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y772_trepa(display_long)|uniprotkb:TP_0772(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589975|imex:IM-9152-1435 author score:0.108892141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882217.1|ensemblbacteria:AAC65742(transcript)|ensemblbacteria:TP_0772(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0772; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:Td/33U9JwEs426+zSqeFSljojs0243276 intact-crc:96CB895B07CBE026|rigid:FNtslNdHh1apYihZWbYcGIywSaM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83228 uniprotkb:O83295 intact:EBI-1590004|ensemblbacteria:AAC65183 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:rs17_trepa(display_long)|uniprotkb:rpsQ(gene name)|psi-mi:rpsQ(display_short)|uniprotkb:TP_0198(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590000|imex:IM-9152-1438 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR019984|interpro:IPR019979|ensemblbacteria:AAC65183(transcript)|ensemblbacteria:TP_0198(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0198|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qNhR0b8RVcjZtOwkp8KA9lNzowo243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:0DF9D63DE746E518|rigid:BboKQHgD6NNUTG3pGYCZWfaMMTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83295 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1589994|imex:IM-9152-1437 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0183|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:544229F61877E9AC|rigid:n07f1zxQV/NbYMvZw5u8w62fRn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83295 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590016|imex:IM-9152-1440 author score:0.67954353 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:0FA4BFFB16D346AD|rigid:JnUs/tg2a8DvVx8F9QfwWaAraiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83327 uniprotkb:O83295 intact:EBI-1198543|intact:EBI-1583552|ensemblbacteria:AAC65292 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:pyrg_trepa(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:TP_0305(locus name)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590010|imex:IM-9152-1439 author score:0.702527915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033828|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|refseq:WP_010881754.1|ensemblbacteria:AAC65292(transcript)|ensemblbacteria:TP_0305(gene)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0046872"(metal ion binding) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0305|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:APACO59bBWxloqEuy3KSnF0gPp8243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:95BC4B7B6E951E64|rigid:bD7stv8q4gTP3Gz0A/ZR+xLEtw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83295 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590028|imex:IM-9152-1442 author score:0.618326259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:F75DFD971A91D06C|rigid:NI8WBbNA34RLcFK/yJgs7snyfF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83295 uniprotkb:O83595 intact:EBI-1589987|ensemblbacteria:AAC65259 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590022|imex:IM-9152-1441 author score:0.630950128 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:5267AF004EC0C664|rigid:BqNCiMw3RJH+y9qPhXEorQrPJEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83295 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590040|imex:IM-9152-1444 author score:0.26131354 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:3C542EC20F9D6E68|rigid:IAJLam/DUc6lvuTtcpj1EeJTXAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83295 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1589987|ensemblbacteria:AAC65259 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590034|imex:IM-9152-1443 author score:0.492731272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 intact-crc:A0B8F35E60AF6F6F|rigid:L5SyAPIpPLoKUgQPRGIrAl9ONvU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83295 uniprotkb:O83958 intact:EBI-1589987|ensemblbacteria:AAC65259 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590052|imex:IM-9152-1446 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8E639BE553B8129F|rigid:ZWo0fQ46sAWvNuJPojri+d5NqMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83295 uniprotkb:O83745 intact:EBI-1589987|ensemblbacteria:AAC65259 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:parb_trepa(display_long)|uniprotkb:parB(gene name)|psi-mi:parB(display_short)|uniprotkb:TP_0271(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590046|imex:IM-9152-1445 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004437(ParB-like partition protein)|interpro:IPR003115(ParB-like nuclease)|ensemblbacteria:AAC65259(transcript)|ensemblbacteria:TP_0271(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010881720.1|interpro:IPR036086|interpro:IPR041468 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0271; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:SD7gC+ry8XhFRBnPYE5Z3I54dSw243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:741CB011859A0573|rigid:cd9oWzQWfvU5ZwHKiDocSU+RxY4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83959 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590064|imex:IM-9152-1447 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0622|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 intact-crc:40B1437F01B11D98|rigid:SSdZqqQ37lozoSybDO8Np/8dp0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83744 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1585682|ensemblbacteria:AAC65734 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:y763_trepa(display_long)|uniprotkb:TP_0763(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590086|imex:IM-9152-1450 author score:0.713656517 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) ensemblbacteria:AAC65734(transcript)|ensemblbacteria:TP_0763(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0763|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:92wDQngr5kpfX9RmKyfjPh9uS2w243276 intact-crc:003E01889713D44C|rigid:D/R5WZTFFPRJUPeIb83IfTfXe8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83941 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1587314|ensemblbacteria:AAC65940 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:y976_trepa(display_long)|uniprotkb:TP_0976(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590080|imex:IM-9152-1449 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) ensemblbacteria:AAC65940(transcript)|ensemblbacteria:TP_0976(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882420.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0976|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:V8k8Iwpz64wTkcgfWQGdwD44zpk243276 intact-crc:C9330291CC6A73B5|rigid:Xa5tDmm2GcH1p07IOBieuI4fuJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83639 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1590070|ensemblbacteria:AAC65606 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590074|imex:IM-9152-1448 author score:0.719126355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0631|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 intact-crc:2F82BD1E4F75F32A|rigid:TJxopd3nGP1mAJBX5sb9oKShGA8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83588 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590092|imex:IM-9152-1451 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0579|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 intact-crc:75D4BD15F0A723B0|rigid:rGkWZgOUbjF/9iaCJTLdfSOycHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83959 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590104|imex:IM-9152-1453 author score:0.248621847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 intact-crc:083AAEFE9D0075FB|rigid:+ITA7VbSOYy6wXdqRuNZ29l9bKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83311 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590098|imex:IM-9152-1452 author score:0.559750072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:C6448DB36B0B136D|rigid:m1xo/9cyPZDxK+A9Ot1FMXT2U1k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83927 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590110|imex:IM-9152-1454 author score:0.215103369 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:49B0321F6FAC46C8|rigid:cyjnDqkoic26pf7iHTLRSgMC5h8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83959 uniprotkb:O83954 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590122|imex:IM-9152-1456 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F777522E0828C096|rigid:JmZMV3TkSmpz4DF0h9dY6dg6sDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83959 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1590061|ensemblbacteria:AAC26582|ensemblbacteria:AGN76158 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83959_trepa(display_long)|uniprotkb:TP_0994(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590116|imex:IM-9152-1455 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001130(Deoxyribonuclease, TatD-related)|interpro:IPR018228|interpro:IPR032466|ensemblbacteria:AAC26582(transcript)|ensemblbacteria:AGN76158(transcript)|ensemblbacteria:TP_0994(gene)|ensemblbacteria:TPANIC_0994(gene)|go:"GO:0016888"(endodeoxyribonuclease activity, producing 5'-phosphomonoesters) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0994; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:v7FtlqNlxdAA84Xuz5HHCL2v68k243276 intact-crc:9FFE14B53481BFDC|rigid:1RW0wqHKu2ipG4rWfHl6ef0L7ls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83697 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1590128|ensemblbacteria:AAC65668 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:y699_trepa(display_long)|uniprotkb:TP_0699(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590137|imex:IM-9152-1458 author score:0.590241526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) ensemblbacteria:AAC65668(transcript)|ensemblbacteria:TP_0699(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0699; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:llVhaC+vxMskYdmU9iuFmTLhD+Q243276 intact-crc:12ACB67E4070B3A3|rigid:SV2aLGyFefzpxTSrzRcCpO9kjmI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83697 uniprotkb:O83261 intact:EBI-1590128|ensemblbacteria:AAC65668 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y699_trepa(display_long)|uniprotkb:TP_0699(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590131|imex:IM-9152-1457 author score:0.717143431 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65668(transcript)|ensemblbacteria:TP_0699(gene) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0699; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:llVhaC+vxMskYdmU9iuFmTLhD+Q243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:77C210C50D8601B1|rigid:jDkOUz0avHaoCqBlasvW/our+7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83697 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1590128|ensemblbacteria:AAC65668 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y699_trepa(display_long)|uniprotkb:TP_0699(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590149|imex:IM-9152-1460 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65668(transcript)|ensemblbacteria:TP_0699(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0699; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:llVhaC+vxMskYdmU9iuFmTLhD+Q243276 intact-crc:438AFB1C6FC0FBF5|rigid:4WSgnDQhmW+vHE+pTR03W/iSYM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83697 uniprotkb:O83877 intact:EBI-1590128|ensemblbacteria:AAC65668 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y699_trepa(display_long)|uniprotkb:TP_0699(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590143|imex:IM-9152-1459 author score:0.15694401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65668(transcript)|ensemblbacteria:TP_0699(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0699; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:llVhaC+vxMskYdmU9iuFmTLhD+Q243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:4D5780D3CED797AA|rigid:hZ4kAAjOkfU3+/Wvd31T1saL+OQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83485 uniprotkb:O83864 intact:EBI-1590165|ensemblbacteria:AAC65452 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 psi-mi:uvrc_trepa(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:TP_0472(locus name) psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590161|imex:IM-9152-1462 author score:0.717143431 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|ensemblbacteria:AAC65452(transcript)|ensemblbacteria:TP_0472(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|interpro:IPR038476|refseq:WP_010881921.1|interpro:IPR035901|interpro:IPR036876 interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0472; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bUWQyS7k78WkRKf02or4yHvi60U243276 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 intact-crc:278648F8AFB9B369|rigid:IBKYa6EQz+eOHVm/oXHZtayIDXE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83697 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590128|ensemblbacteria:AAC65668 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y699_trepa(display_long)|uniprotkb:TP_0699(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590155|imex:IM-9152-1461 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65668(transcript)|ensemblbacteria:TP_0699(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0699; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:llVhaC+vxMskYdmU9iuFmTLhD+Q243276 intact-crc:CA6D941D71FA1488|rigid:PSzVL0DHrN/jtS7zvBN41v3dOqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83485 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1590165|ensemblbacteria:AAC65452 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:uvrc_trepa(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:TP_0472(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590177|imex:IM-9152-1464 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|ensemblbacteria:AAC65452(transcript)|ensemblbacteria:TP_0472(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|interpro:IPR038476|refseq:WP_010881921.1|interpro:IPR035901|interpro:IPR036876 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0472; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:bUWQyS7k78WkRKf02or4yHvi60U243276 intact-crc:174FF454EBB97971|rigid:ZEu8olV4QGXq+wV1cIAD+gpUBlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83485 uniprotkb:O83969 intact:EBI-1590165|ensemblbacteria:AAC65452 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:uvrc_trepa(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:TP_0472(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590171|imex:IM-9152-1463 author score:0.53674765 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|ensemblbacteria:AAC65452(transcript)|ensemblbacteria:TP_0472(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|interpro:IPR038476|refseq:WP_010881921.1|interpro:IPR035901|interpro:IPR036876 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0472; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bUWQyS7k78WkRKf02or4yHvi60U243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:BC924BE5087C9CC8|rigid:h86a+TBXRBHqSZJsGQ5we9x6erw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83485 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590165|ensemblbacteria:AAC65452 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:uvrc_trepa(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:TP_0472(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590189|imex:IM-9152-1466 author score:0.002380093 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|ensemblbacteria:AAC65452(transcript)|ensemblbacteria:TP_0472(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|interpro:IPR038476|refseq:WP_010881921.1|interpro:IPR035901|interpro:IPR036876 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0472; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:bUWQyS7k78WkRKf02or4yHvi60U243276 intact-crc:C908301293D9FC8F|rigid:8i0tsz//BbVETzoxcVVa4LkAXlQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83485 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1590165|ensemblbacteria:AAC65452 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:uvrc_trepa(display_long)|uniprotkb:uvrC(gene name)|psi-mi:uvrC(display_short)|uniprotkb:Excinuclease ABC subunit C(gene name synonym)|uniprotkb:TP_0472(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590183|imex:IM-9152-1465 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR010994(RuvA domain 2-like)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR004791(Excinuclease ABC, C subunit)|interpro:IPR001162(Excinuclease ABC, C subunit, C-terminal)|interpro:IPR000305(Excinuclease ABC, C subunit, N-terminal)|ensemblbacteria:AAC65452(transcript)|ensemblbacteria:TP_0472(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|interpro:IPR038476|refseq:WP_010881921.1|interpro:IPR035901|interpro:IPR036876 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0472; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:bUWQyS7k78WkRKf02or4yHvi60U243276 intact-crc:53AB308E5D7394BB|rigid:P7wpR5ZSZr/Xw5k9+eCBc9Rcx4M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56343 uniprotkb:O83706 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590204|imex:IM-9152-1468 author score:0.704262981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 intact-crc:B7ADAA4D78B3AE24|rigid:MpD2bpW1haeDZGsVM5BISgfP14A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56343 uniprotkb:O83392 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590195|imex:IM-9152-1467 author score:0.715352973 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:BF5FA5C77EE08EA3|rigid:76zsgThmfLDwynQB0gOyKoHaBbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56343 uniprotkb:O83887 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590216|imex:IM-9152-1470 author score:0.474639803 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:2B7E82741D533854|rigid:dCGGu35NiqI1nYNkBTuDGwYmMvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:Q56343 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590210|imex:IM-9152-1469 author score:0.508270364 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 intact-crc:6D287426103EA6D1|rigid:G5lQstpM/OT/Ovwjrb4uce5A1C0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56343 uniprotkb:O83745 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590228|imex:IM-9152-1472 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:62C175FDA0F1B7ED|rigid:+iHC9ns3W02YrEaGen69mm7U9fE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56343 uniprotkb:O83413 intact:EBI-1590199|ensemblbacteria:AAC65034|ensemblbacteria:AGN75259 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:q56343_trepa(display_long)|uniprotkb:TP_0038(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590222|imex:IM-9152-1471 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003352(Phosphotransferase system, EIIC)|ensemblbacteria:AAC65034(transcript)|ensemblbacteria:AGN75259(transcript)|ensemblbacteria:TP_0038(gene)|ensemblbacteria:TPANIC_0038(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881487.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0038; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hmH7n9+xEZbrOOhUlx9tohg8uyw243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:D33BFCCB216A4640|rigid:t6AvnayWLIqaVQhBtcjgJElyKig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:Q56339 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1198657|intact:EBI-1585551|ensemblbacteria:AAC65679 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:flhf_trepa(display_long)|uniprotkb:flhF(gene name)|psi-mi:flhF(display_short)|uniprotkb:TP_0713(locus name)|uniprotkb:Flagella-associated GTP-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590234|imex:IM-9152-1473 author score:0.715327779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR020006|interpro:IPR027417|refseq:WP_010882158.1|ensemblbacteria:AAC65679(transcript)|ensemblbacteria:TP_0713(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0044781"(bacterial-type flagellum organization) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0713; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:NqgYRAuKzoUTtoW2Rj35sI57Pbg243276 intact-crc:FECD44507AB5E3BC|rigid:nUjxx0hVxlkuJHk6nnjS2mv0t0Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:Q56339 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198657|intact:EBI-1585551|ensemblbacteria:AAC65679 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:flhf_trepa(display_long)|uniprotkb:flhF(gene name)|psi-mi:flhF(display_short)|uniprotkb:TP_0713(locus name)|uniprotkb:Flagella-associated GTP-binding protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590240|imex:IM-9152-1474 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR020006|interpro:IPR027417|refseq:WP_010882158.1|ensemblbacteria:AAC65679(transcript)|ensemblbacteria:TP_0713(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0044781"(bacterial-type flagellum organization) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0713; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:NqgYRAuKzoUTtoW2Rj35sI57Pbg243276 intact-crc:6C5BF0925A23ECBB|rigid:8BqqprMNpHUDF5iZ25ie+oww/DQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83278 uniprotkb:O83939 intact:EBI-1590250|ensemblbacteria:AAC65236 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:dbh_trepa(display_long)|uniprotkb:hup(gene name)|psi-mi:hup(display_short)|uniprotkb:TP_0251(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590246|imex:IM-9152-1475 author score:0.713354028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000119(Histone-like bacterial DNA-binding protein)|interpro:IPR010992(IHF-like DNA-binding)|ensemblbacteria:AAC65236(transcript)|ensemblbacteria:TP_0251(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0030261"(chromosome condensation)|refseq:WP_010881700.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0251; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fARwXdsSwvmvNVVVtnWaUYjP6Go243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:F1F95F9AB283BA0E|rigid:H6/jpUX7l/LySJkrBmH23PuOxBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83890 uniprotkb:O83119 intact:EBI-1583720|ensemblbacteria:AAC65878 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590265|imex:IM-9152-1477 author score:0.711751669 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:F21EC94216EDDC8D|rigid:YYB+M2rEU+eE5IbYvOuwFqC0U8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83707 uniprotkb:O83939 intact:EBI-1198636|intact:EBI-1590256|ensemblbacteria:AAC65675 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83707_trepa(display_long)|uniprotkb:TP_0709(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590259|imex:IM-9152-1476 author score:0.713354028 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR012845(RNA polymerase sigma factor, FliA/WhiG)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|ensemblbacteria:AAC65675(transcript)|ensemblbacteria:TP_0709(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|refseq:WP_010882154.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0709; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H40wcpB8z/eTw7KVHc8Wk2zPeU8243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:4C302AF3CB7E1619|rigid:zPTaifWLrwnhsfxHrFj9vnchR4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83570 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590271|imex:IM-9152-1478 author score:0.596855422 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:0418DF256CCAABA9|rigid:UB2VEmtgiSxLbT58vobJW+kkhBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83531 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590277|imex:IM-9152-1479 author score:0.31169449 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:0057DF171C712D4E|rigid:d5UliKa2WAB40nFhbE4YF/sB2Go false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83119 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590283|imex:IM-9152-1480 author score:0.289071214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:EA65E3CDC000BDD1|rigid:i13Pi88cE/v9egK9x8YnhxH93hU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83877 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590289|imex:IM-9152-1481 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:256EF7E74F52DDB5|rigid:JubNqLs7KfKcH24SKJvm9ao42Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83767 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590295|imex:IM-9152-1482 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:25FD46BC351CE8B1|rigid:GQzyHWrplVp7A2oe8GtEaCqAN5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83119 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590307|imex:IM-9152-1484 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:CFD04FDF6482ACA7|rigid:M9/nKMOCj50+3ci+52y1ppckqPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83954 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590301|imex:IM-9152-1483 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0080; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:A9B925FC5260E915|rigid:Us0FTAGpsumfFEi3kwL2fF+hxhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:P96131 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1583755|ensemblbacteria:AAC65347 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:rl28_trepa(display_long)|uniprotkb:rpmB(gene name)|psi-mi:rpmB(display_short)|uniprotkb:rpl28(gene name synonym)|uniprotkb:TP_0362(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590319|imex:IM-9152-1486 author score:0.397406982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR001383(Ribosomal protein L28)|interpro:IPR034704|interpro:IPR026569|ensemblbacteria:AAC65347(transcript)|ensemblbacteria:TP_0362(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881810.1|interpro:IPR037147 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0362; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:77S9butCz8qvXZGwBHz17pmfbNk243276 intact-crc:13F68FA5F2C01898|rigid:zuAR7uuMcg8MuysJK+hfNSQ6KRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96131 uniprotkb:O83098 intact:EBI-1583755|ensemblbacteria:AAC65347 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:rl28_trepa(display_long)|uniprotkb:rpmB(gene name)|psi-mi:rpmB(display_short)|uniprotkb:rpl28(gene name synonym)|uniprotkb:TP_0362(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590313|imex:IM-9152-1485 author score:0.711549231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001383(Ribosomal protein L28)|interpro:IPR034704|interpro:IPR026569|ensemblbacteria:AAC65347(transcript)|ensemblbacteria:TP_0362(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881810.1|interpro:IPR037147 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0362; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:77S9butCz8qvXZGwBHz17pmfbNk243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:1804A1602798FED0|rigid:YIpgUHA5sQXFseLJhwjNvPH6oV8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83264 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590329|imex:IM-9152-1487 author score:0.709940886 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0236|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 intact-crc:C4529DC065A39DDF|rigid:Bq0gH7XARhpm2ANWQQUpwvlRuCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83627 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590335|imex:IM-9152-1488 author score:0.594733834 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:0BDAC68CFB9C377D|rigid:jx9YvKj9i8R8sqa0pwjOTk83Knw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83565 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590341|imex:IM-9152-1489 author score:0.535258292 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:4E4A4BD5316EA69A|rigid:8Bp05t3sez0ZQBUsD/sEaZuYPfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83305 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590347|imex:IM-9152-1490 author score:0.333292903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:74BF0BE0C99499DB|rigid:p77eEdAEBwMapgTpys72dZXTx20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83875 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1590325|ensemblbacteria:AAC65857 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590359|imex:IM-9152-1492 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 intact-crc:B7599308DE56C6BA|rigid:RZnW88lKgl5TTmOaoVOnwSgEvSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83531 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590353|imex:IM-9152-1491 author score:0.298413524 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:FF3652B641C7C64F|rigid:LMK9gAYXpD9Jz+ZPpKRW4UW/fjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83875 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1590325|ensemblbacteria:AAC65857 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590371|imex:IM-9152-1494 author score:0.225870273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 intact-crc:9AF2BF71686D0CFB|rigid:Yo422QvQSFNHS9RgfVjUqWf0EVA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83875 uniprotkb:O83282 intact:EBI-1590325|ensemblbacteria:AAC65857 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590377|imex:IM-9152-1495 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8C79DC2AD20F54AE|rigid:xKCWYHEk1yD+4Cgb/kxOdzu9lJY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83875 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1590325|ensemblbacteria:AAC65857 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rs16_trepa(display_long)|uniprotkb:rpsP(gene name)|psi-mi:rpsP(display_short)|uniprotkb:TP_0905(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590365|imex:IM-9152-1493 author score:0.255356726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR000307(Ribosomal protein S16)|interpro:IPR023803|ensemblbacteria:AAC65857(transcript)|ensemblbacteria:TP_0905(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882348.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0905; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:MG7zkp830lUWIoOLNwWDUdV277U243276 intact-crc:77207DFB1A4AD262|rigid:HkRYqRA22H1CGRU5FVrBUxCWVpg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83551 uniprotkb:O83702 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590386|imex:IM-9152-1496 author score:0.709839301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:F0791FCC26E48A8B|rigid:jptAMwtApow7kEVUtyuMA6CNutk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83551 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590392|imex:IM-9152-1497 author score:0.343110574 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 intact-crc:FD9B94DF6BE8287E|rigid:tAJotyBw0T+/luIwC5fJY+jX5z0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83551 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590398|imex:IM-9152-1498 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 intact-crc:33D9CFCC7178A8EC|rigid:y+xvHHhy6CpPu33oq6DeHVSjMVY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83551 uniprotkb:O83574 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590404|imex:IM-9152-1499 author score:0.216510799 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:5204F12BB992D733|rigid:almW8xPro+fmABjKAqbiH9HZqn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83551 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590410|imex:IM-9152-1500 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 intact-crc:F388FEBD273405E3|rigid:RhcgueIrKOuJYqBHGyBxV4gQpeU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83383 uniprotkb:O83814 intact:EBI-1584764|ensemblbacteria:AAC65359 intact:EBI-1582504|ensemblbacteria:AAC65810 psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:map1_trepa(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:Peptidase M(gene name synonym)|uniprotkb:TP_0842(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590422|imex:IM-9152-1502 author score:0.708123392 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 interpro:IPR001714(Peptidase M24, methionine aminopeptidase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR002467(Peptidase M24A, methionine aminopeptidase, subfamily 1)|ensemblbacteria:AAC65810(transcript)|ensemblbacteria:TP_0842(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070084"(protein initiator methionine removal)|refseq:WP_010882286.1|interpro:IPR036005 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0842|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 rogid:0YVfJeQeD6b1q3jKeQzHWaUblog243276 intact-crc:1BF3D34679EC9638|rigid:1bhkDH9dISAkLnMWTPk5SqyjDmE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83551 uniprotkb:O83745 intact:EBI-1590383|ensemblbacteria:AAC65524|ensemblbacteria:AGN75727 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83551_trepa(display_long)|uniprotkb:TP_0540(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590416|imex:IM-9152-1501 author score:0.124016599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|ensemblbacteria:AAC65524(transcript)|ensemblbacteria:AGN75727(transcript)|ensemblbacteria:TP_0540(gene)|ensemblbacteria:TPANIC_0540(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0540; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8NMlCdVMmrg13Y6eS4J8f8wORlQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:D87535DD19AB96E4|rigid:pqWf2NzwE8B3yTfMf5Mf3cm+xVM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83383 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590434|imex:IM-9152-1504 author score:0.519643121 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:E9499B78C01425A3|rigid:KTft6VHvCSFNX2WkFhalbZiqYic false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83383 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590428|imex:IM-9152-1503 author score:0.559750072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:B45870333E1D5F97|rigid:IcHy2JVn/Kay1hqyq7jcI/kUi9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83383 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590440|imex:IM-9152-1505 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:77FDBEAFAEFEE08D|rigid:UvxwsKDZi3r6wjidy+TEEnqATh8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83383 uniprotkb:O83531 intact:EBI-1584764|ensemblbacteria:AAC65359 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590446|imex:IM-9152-1506 author score:0.285463752 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:099AE2EAF1589C65|rigid:HWq0G+m8NzcConlbIntzxvNGqME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83383 uniprotkb:O83099 intact:EBI-1584764|ensemblbacteria:AAC65359 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590452|imex:IM-9152-1507 author score:0.243626594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:2E80A6CFECEA8B0D|rigid:voPO0OB0EpRohdJsUuv3XdEfurs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83383 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590464|imex:IM-9152-1509 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:921C01BF890F656B|rigid:RbLZGHJTK01p+q5xMyjUm5Y3xu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83383 uniprotkb:O83667 intact:EBI-1584764|ensemblbacteria:AAC65359 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590458|imex:IM-9152-1508 author score:0.101298891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:5612D8C3BD0EA0F7|rigid:09tlj+GuJ0vqNmmZTZIKs6OpG78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83383 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590476|imex:IM-9152-1511 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:3600785EEC93AA14|rigid:+dAw2o18VQi8MuLFL+oijBWaSoQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83383 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1584764|ensemblbacteria:AAC65359 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y368_trepa(display_long)|uniprotkb:TP_0368(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590470|imex:IM-9152-1510 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65359(transcript)|ensemblbacteria:TP_0368(gene)|refseq:WP_010881816.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0368; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:HND9dSEH3hfbxN7b8aSAQmLDwbE243276 intact-crc:7C637C65AD30E505|rigid:2J6mSYpZRAsjd8cVmZ+lBMmz70s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83886 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1590482|ensemblbacteria:AAC65877 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y916_trepa(display_long)|uniprotkb:TP_0916(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590485|imex:IM-9152-1512 author score:0.707817451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) ensemblbacteria:AAC65877(transcript)|ensemblbacteria:TP_0916(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0916; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:RejAu9qgl1pmBfw2h/+enCep7uw243276 intact-crc:AD52BE7F13901327|rigid:ACqkekfEsUjrkcn9XDZJ4H+PBBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83068 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590503|imex:IM-9152-1514 author score:0.616245014 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:DA60EC030DCC822B|rigid:uUkYgSC3b19fP53bQtSr+YI/bM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83125 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590494|imex:IM-9152-1513 author score:0.706299221 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0688|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 intact-crc:6E22CD48A96E68C3|rigid:v+Pxr08n+cGBr6x4VmdALsiuHew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83125 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590521|imex:IM-9152-1517 author score:0.430407445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 intact-crc:B9520B48677CC3F8|rigid:KQOaEcGhU1iNDFgi8BJKHRiaweM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83752 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590515|imex:IM-9152-1516 author score:0.524162585 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:8FE4D0035A4CCB32|rigid:v8KQpCELDD8/PuoKbB0mt4AltbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83939 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590509|imex:IM-9152-1515 author score:0.570816448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:D7C4E02132C564DF|rigid:mVlouFFPDeLdlmjn+Dk527GgIQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83312 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590533|imex:IM-9152-1519 author score:0.237102582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:EBE2D0083F26D1B8|rigid:65oKHq+YZjfSwD8fuGxvEUXL8Ko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83463 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590527|imex:IM-9152-1518 author score:0.384936692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:F99EBB8155584685|rigid:XyYEsdmarQURoq5j8p9fgS7rvw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83413 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590545|imex:IM-9152-1521 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CF68EE4051FB49FC|rigid:5BpfQuwRR+C1lMXEZMTdXAxTh4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83125 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590539|imex:IM-9152-1520 author score:0.168066845 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 intact-crc:F0CAC6C880C44381|rigid:jRXVaHW0NkQ5XT22vVST2wtArjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83282 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590557|imex:IM-9152-1868 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:EDD4990F51D35A85|rigid:QJ+AK2jCKM5TwH7VzjCXkMDWkSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83125 uniprotkb:O83667 intact:EBI-1590498|ensemblbacteria:AAC65082|ensemblbacteria:AGN75306 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83125_trepa(display_long)|uniprotkb:TP_0087(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590551|imex:IM-9152-1522 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003795(Protein of unknown function DUF192)|ensemblbacteria:AAC65082(transcript)|ensemblbacteria:TP_0087(gene)|ensemblbacteria:TPANIC_0087(gene)|ensemblbacteria:AGN75306(transcript)|interpro:IPR038695 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0087; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2BwJ79tALQ3XLy7JlMM9Nl0C+Qo243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:53BA872938275060|rigid:6JQTrPrbXEu0jTkkvDd7LwVRxEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83822 uniprotkb:O83133 intact:EBI-1584640|ensemblbacteria:AAC65816 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590572|imex:IM-9152-1870 author score:0.694771301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:941CB9D037B8B337|rigid:FW3tba8T7vG6StyDbwrPaqpJO38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83876 uniprotkb:O83822 intact:EBI-1590563|ensemblbacteria:AAC65858 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:y906_trepa(display_long)|uniprotkb:TP_0906(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590566|imex:IM-9152-1869 author score:0.706299221 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR020627|interpro:IPR015946(K homology-like, alpha/beta)|ensemblbacteria:AAC65858(transcript)|ensemblbacteria:TP_0906(gene)|go:"GO:0003723"(RNA binding) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0906|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ztZdpo9fvxIqrxId/E5ul1Vpceg243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:71869212902B10DD|rigid:EC2NMeBOWQtu/RP8nP7sr2CyLzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83822 uniprotkb:O83670 intact:EBI-1584640|ensemblbacteria:AAC65816 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590584|imex:IM-9152-1872 author score:0.497258971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:874162A6FCCF212E|rigid:UuQLd8WpIx77JCALciEzZUPcK5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83822 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590578|imex:IM-9152-1871 author score:0.622591587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:AF6D67613EA40AE4|rigid:2w2xPiMt+qlSGuTLLr4jQX4Y6pU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83822 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590590|imex:IM-9152-1873 author score:0.384936692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:71EA00565A49447A|rigid:v3l0guLQqXu+yERNatv0HuC6c98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83822 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590602|imex:IM-9152-1875 author score:0.227501077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:65611D1FD28D6D60|rigid:OcMWIAlbq+DRPfjk2pR1GKZFzXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83822 uniprotkb:O83877 intact:EBI-1584640|ensemblbacteria:AAC65816 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590596|imex:IM-9152-1874 author score:0.23732529 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:AEAB35DD4B858552|rigid:FFnYUL7AldbVqpPCc2LCBfoi/QU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83822 uniprotkb:O83767 intact:EBI-1584640|ensemblbacteria:AAC65816 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590614|imex:IM-9152-1877 author score:0.066028043 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:F062FA3C17A50B00|rigid:oGpRjpokC3GuFKPNcFTJi+J0kkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83822 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590608|imex:IM-9152-1876 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:5C74AD4145E8DE6A|rigid:YkM2F65a3CibketxHOp9fP3loBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83822 uniprotkb:O83954 intact:EBI-1584640|ensemblbacteria:AAC65816 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590626|imex:IM-9152-1879 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:6CE0E60D6647BD60|rigid:AfS/wVavwmpIhqDarcS9tSShYNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83822 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1584640|ensemblbacteria:AAC65816 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:if3_trepa(display_long)|uniprotkb:infC(gene name)|psi-mi:infC(display_short)|uniprotkb:TP_0850(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590620|imex:IM-9152-1878 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR019813|interpro:IPR001288(Initiation factor 3)|interpro:IPR019815|interpro:IPR019814|ensemblbacteria:AAC65816(transcript)|ensemblbacteria:TP_0850(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR036787|interpro:IPR036788 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0850; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:qPRL0Pi5jcIO+s39i6vQMb7hMm0243276 intact-crc:ABDBFF17ABDCC6AA|rigid:Q4q/hzXJDOwaIbLPYp6cTxJb2Uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83963 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1590632|ensemblbacteria:AAC26586 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83963_trepa(display_long)|uniprotkb:TP_0998(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590639|imex:IM-9152-1880 author score:0.706299221 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 interpro:IPR001463("Sodium:alanine symporter")|ensemblbacteria:AAC26586(transcript)|ensemblbacteria:TP_0998(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015655"("alanine:sodium symporter activity")|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0998|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:Uue/GnCsZ0xoyL5qw+AybPEbQ+o243276 intact-crc:17E5048A74A7D9E5|rigid:esQjiaqihrLATX5jAKWopvIqEsA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83392 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590655|imex:IM-9152-1882 author score:0.647542122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:32E9DE78514D8B43|rigid:aHH3uDekaoBrJfujVUQuO1LuIN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83151 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1590645|ensemblbacteria:AAC65102 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:hflk_trepa(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:TP_0113(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590649|imex:IM-9152-1881 author score:0.700683555 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|ensemblbacteria:AAC65102(transcript)|ensemblbacteria:TP_0113(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881562.1|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0113|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:qyf2DLEImKw76cyCTbyhQtIKMhg243276 intact-crc:FAFF6738CE3E475E|rigid:U/rQErTgUmXUaCr8dvjPZ4ton24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83514 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1590635|ensemblbacteria:AAC65488 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590667|imex:IM-9152-1884 author score:0.533889674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 intact-crc:7FF4088A50CACDB3|rigid:Kupoq2JiC1MnM8V3aLqlpUWbQfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83706 uniprotkb:O83514 intact:EBI-1198366|intact:EBI-1581613|ensemblbacteria:AAC65695 intact:EBI-1590635|ensemblbacteria:AAC65488 psi-mi:y708_trepa(display_long)|uniprotkb:TP_0708(locus name) psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590661|imex:IM-9152-1883 author score:0.635157622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882153.1|ensemblbacteria:AAC65695(transcript)|ensemblbacteria:TP_0708(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0708|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uaLJwfQbTc5vrye7GTPF/IACbXk243276 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 intact-crc:8425C6BF64D64139|rigid:vUIobLzvDA2SbPu/2fkN8DzOfnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83927 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590679|imex:IM-9152-1886 author score:0.267654929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:2A36CC84C6380E00|rigid:bEl2wuV3F92wOQcWDibaUEAkp0o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83572 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590673|imex:IM-9152-1885 author score:0.430407445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:72B78546DB26323B|rigid:VPc8l1WRe1lIP/4MYYOwL+yAlZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83514 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1590635|ensemblbacteria:AAC65488 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590685|imex:IM-9152-1887 author score:0.168066845 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 intact-crc:8637C12470017B71|rigid:/Oldm05iH2XFfnYOpsaeda/wrjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83954 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590697|imex:IM-9152-1889 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F2E6ABF740AA6A61|rigid:treSAfI7r6cPmoLEOCemmnji8lM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83514 uniprotkb:O83282 intact:EBI-1590635|ensemblbacteria:AAC65488 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590691|imex:IM-9152-1888 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:1964A31C68B3BAD4|rigid:MF7cWMCPzQeNmfWdvatFMGidnvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83514 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590635|ensemblbacteria:AAC65488 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:roda_trepa(display_long)|uniprotkb:rodA(gene name)|psi-mi:rodA(display_short)|uniprotkb:Cell elongation protein RodA(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:mrdB(gene name synonym)|uniprotkb:TP_0501(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590703|imex:IM-9152-1890 author score:0.005451816 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001182(Cell cycle protein)|interpro:IPR018365|interpro:IPR011923(Rod shape-determining protein RodA)|ensemblbacteria:AAC65488(transcript)|ensemblbacteria:TP_0501(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010881950.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0501; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:/m3K4E8CyTXZHy7tNPwq9L4v090243276 intact-crc:9BCFC7D637B37D2E|rigid:O1Kyo/aEhV4L6+ge4ynVwgKnDHI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83661 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590715|imex:IM-9152-1892 author score:0.603316244 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 intact-crc:1DCDDB38D90312A3|rigid:Xi0dhGszI7gVfbCmLKRLvCYepOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83661 uniprotkb:O83723 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590709|imex:IM-9152-1891 author score:0.706196889 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:DD5F8F68385EBD16|rigid:fsqSnstIcRmI3GPJZsP5VDr3t+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83661 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590721|imex:IM-9152-1893 author score:0.570695602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 intact-crc:EA79C0D3F7C8E773|rigid:rq7j+VlVMDGvc+DO2/66NXBKwAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83661 uniprotkb:P21992 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590733|imex:IM-9152-1895 author score:0.375942967 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:845CD0912174FA58|rigid:9ISHq/2VDWfcD2BdZP5C09ljRnY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83661 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590727|imex:IM-9152-1894 author score:0.430286523 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 intact-crc:1B271DC36085870C|rigid:i4WAVLLZRI+Ul+qmsf/AD91RmiE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83661 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590745|imex:IM-9152-1897 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 intact-crc:635C19CE702EC1F5|rigid:7MEFz9rWq09DknE1Gnh0x5eGXac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83661 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590739|imex:IM-9152-1896 author score:0.347357628 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 intact-crc:AA426E8E918A613F|rigid:uiA0Ti9mfezZN/V1Rof/Iom3nDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83689 uniprotkb:O83227 intact:EBI-1590757|ensemblbacteria:AAC65659|ensemblbacteria:AGN75869 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:o83689_trepa(display_long)|uniprotkb:TP_0691(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590760|imex:IM-9152-1899 author score:0.706094536 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003768(Prokaryotic chromosome segregation and condensation protein ScpA)|ensemblbacteria:AAC65659(transcript)|ensemblbacteria:AGN75869(transcript)|ensemblbacteria:TP_0691(gene)|ensemblbacteria:TPANIC_0691(gene)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010882136.1|interpro:IPR023093 interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0691; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9jQ3XWu5CnSlU7kCw4g/UrzDTSw243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:F430CA30171284D5|rigid:DIRF1DVFGuDc/adg9p8MWby656k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83661 uniprotkb:O83667 intact:EBI-1586295|ensemblbacteria:AAC65630|ensemblbacteria:AGN75834 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83661_trepa(display_long)|uniprotkb:TP_0655(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590751|imex:IM-9152-1898 author score:0.113290143 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR001188(Bacterial periplasmic spermidine/putrescine-binding protein)|rcsb pdb:2V84|ensemblbacteria:AAC65630(transcript)|ensemblbacteria:AGN75834(transcript)|ensemblbacteria:TP_0655(gene)|ensemblbacteria:TPANIC_0655(gene)|go:"GO:0015846"(polyamine transport)|go:"GO:0019808"(polyamine binding)|go:"GO:0042597"(periplasmic space)|refseq:WP_010882100.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0655; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:imA1g5pDGAv6Q0rdLSlI3tD05kA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:9F8A74C7F6C1ED8C|rigid:YnIgzLa+HPaoGLs9owM/Yp7DQoM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83689 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1590757|ensemblbacteria:AAC65659|ensemblbacteria:AGN75869 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83689_trepa(display_long)|uniprotkb:TP_0691(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590772|imex:IM-9152-1901 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003768(Prokaryotic chromosome segregation and condensation protein ScpA)|ensemblbacteria:AAC65659(transcript)|ensemblbacteria:AGN75869(transcript)|ensemblbacteria:TP_0691(gene)|ensemblbacteria:TPANIC_0691(gene)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010882136.1|interpro:IPR023093 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0691; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:9jQ3XWu5CnSlU7kCw4g/UrzDTSw243276 intact-crc:6AC0CCEECEEB419A|rigid:pq8efbdSXh++g5lem5QT7N9fLJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83689 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1590757|ensemblbacteria:AAC65659|ensemblbacteria:AGN75869 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83689_trepa(display_long)|uniprotkb:TP_0691(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590766|imex:IM-9152-1900 author score:0.3001576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR003768(Prokaryotic chromosome segregation and condensation protein ScpA)|ensemblbacteria:AAC65659(transcript)|ensemblbacteria:AGN75869(transcript)|ensemblbacteria:TP_0691(gene)|ensemblbacteria:TPANIC_0691(gene)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010882136.1|interpro:IPR023093 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0691; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:9jQ3XWu5CnSlU7kCw4g/UrzDTSw243276 intact-crc:9EBA2E003B1A926B|rigid:ByN2Bs/1yGhlwRsvtoY00m2nSF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83689 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1590757|ensemblbacteria:AAC65659|ensemblbacteria:AGN75869 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83689_trepa(display_long)|uniprotkb:TP_0691(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590784|imex:IM-9152-1903 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003768(Prokaryotic chromosome segregation and condensation protein ScpA)|ensemblbacteria:AAC65659(transcript)|ensemblbacteria:AGN75869(transcript)|ensemblbacteria:TP_0691(gene)|ensemblbacteria:TPANIC_0691(gene)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010882136.1|interpro:IPR023093 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0691; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:9jQ3XWu5CnSlU7kCw4g/UrzDTSw243276 intact-crc:E281219B91E4C125|rigid:iEL0TFwacJD2wrNk7XMsQFvm/RE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83689 uniprotkb:O83767 intact:EBI-1590757|ensemblbacteria:AAC65659|ensemblbacteria:AGN75869 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83689_trepa(display_long)|uniprotkb:TP_0691(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590778|imex:IM-9152-1902 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003768(Prokaryotic chromosome segregation and condensation protein ScpA)|ensemblbacteria:AAC65659(transcript)|ensemblbacteria:AGN75869(transcript)|ensemblbacteria:TP_0691(gene)|ensemblbacteria:TPANIC_0691(gene)|go:"GO:0007059"(chromosome segregation)|refseq:WP_010882136.1|interpro:IPR023093 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0691; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9jQ3XWu5CnSlU7kCw4g/UrzDTSw243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:4A41AFCE83A5EC2D|rigid:7YZuJuC7XHs76dqvYkh4diRMLFw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83670 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590796|imex:IM-9152-1905 author score:0.663565457 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:741935B36DE3B49A|rigid:33IRbT+CdP+ka+/dWaYz4zLZnQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83261 uniprotkb:O83670 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590790|imex:IM-9152-1904 author score:0.704262981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:9876B5748ADAFB68|rigid:evBRQhSa1+zbe37p0cGu4KJFTB0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83745 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590808|imex:IM-9152-1907 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:A5E3959A7656E778|rigid:IgHM4WdPwGlYLDZTNJWdf3u2mXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83670 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590802|imex:IM-9152-1906 author score:0.260414641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:A9814D981BE3DFF3|rigid:JW8sFxYNcYVI1jm/ERqa6E+izOY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83670 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590820|imex:IM-9152-1909 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:C298DC4F0A2B963B|rigid:HMEpUXU1XbyUQr/3gHgLGiPj0mQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83670 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590814|imex:IM-9152-1908 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0664; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:3B2E95B6E468ECD1|rigid:Y/dOzYJYDzkWa2QLnRiaZ8SuCgE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83943 uniprotkb:O83392 intact:EBI-1590830|ensemblbacteria:AAC65933 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590826|imex:IM-9152-1910 author score:0.702424822 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0377|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:990BF5B846FEBE7C|rigid:dWT+cG7V6XIt4tX+GKKX+LvRfDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83943 uniprotkb:O83099 intact:EBI-1590830|ensemblbacteria:AAC65933 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590842|imex:IM-9152-1912 author score:0.376846305 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:1EEE7300548CD3D8|rigid:N+GCZRGzuJYb4Ih1DUpNYV3Oa0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83943 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1590830|ensemblbacteria:AAC65933 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590836|imex:IM-9152-1911 author score:0.459046304 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 intact-crc:61EF1225DCB65B1F|rigid:wXMSWyJhHs4HTVfy315tA+vQPr4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83943 uniprotkb:O83877 intact:EBI-1590830|ensemblbacteria:AAC65933 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590848|imex:IM-9152-1913 author score:0.207871443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C3F48AD802289FA3|rigid:0gBpA51qbMkpaG9w5T76bj/iSNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83943 uniprotkb:O83954 intact:EBI-1590830|ensemblbacteria:AAC65933 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590860|imex:IM-9152-1915 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4002104FDDE8D16C|rigid:bEHr9ZzG0H0l6moYvB76KD6d7AU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83943 uniprotkb:O83282 intact:EBI-1590830|ensemblbacteria:AAC65933 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590854|imex:IM-9152-1914 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:19A0941AC2D4671E|rigid:+ttcBFcoccM8e8eaPjjHqYD1eO8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:P45685 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590872|imex:IM-9152-1917 author score:0.702321709 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0741; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:8FA6AED38534AD5B|rigid:7delrH+imKJrolVsyl+ZBt5TJdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83943 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590830|ensemblbacteria:AAC65933 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:lspa_trepa(display_long)|uniprotkb:lspA(gene name)|psi-mi:lspA(display_short)|uniprotkb:lsp(gene name synonym)|uniprotkb:Prolipoprotein signal peptidase(gene name synonym)|uniprotkb:Signal peptidase II(gene name synonym)|uniprotkb:TP_0978(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590866|imex:IM-9152-1916 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001872(Peptidase A8, signal peptidase II)|ensemblbacteria:AAC65933(transcript)|ensemblbacteria:TP_0978(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0978; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:k6/SNJIrfaCxVkx8rlbGvfVIDkg243276 intact-crc:351063DA3F2560A8|rigid:5iRnXFPRhDZy6hilXsvT86jGWeE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:O83282 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590884|imex:IM-9152-1919 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0741; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:7CCA583E71027714|rigid:BaVGnRAgLJe7SxOKvq+2qpxdB1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:O83239 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590878|imex:IM-9152-1918 author score:0.649325558 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0741; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:A156AFD640EDA118|rigid:lTQv8trzMZO7aHKrmicwdHIdNuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83660 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1590910|ensemblbacteria:AAC65629|ensemblbacteria:AGN75833 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83660_trepa(display_long)|uniprotkb:TP_0654(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590906|imex:IM-9152-1922 author score:0.702218575 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|ensemblbacteria:AAC65629(transcript)|ensemblbacteria:AGN75833(transcript)|ensemblbacteria:TP_0654(gene)|ensemblbacteria:TPANIC_0654(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010882099.1|interpro:IPR035906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0654; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:9oz6Z8WtgDqlE0hO/Wa1Ge0RCgI243276 intact-crc:92CAD2AA09118E67|rigid:/JQsQIbaw/V/qGpu2m+zS4UpnCY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83649 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1590900|ensemblbacteria:AAC65617 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:dpo3e_trepa(display_long)|uniprotkb:dnaQ(gene name)|psi-mi:dnaQ(display_short)|uniprotkb:TP_0643(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590896|imex:IM-9152-1921 author score:0.702218575 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR006054(DNA polymerase III, epsilon subunit)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|ensemblbacteria:AAC65617(transcript)|ensemblbacteria:TP_0643(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882088.1|interpro:IPR036397 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0643; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:KIjWbowGmeh/rr5rQIOm/HUwLd0243276 intact-crc:340A0A70D0200DBA|rigid:ByxYXS5hOPiISn9sWoVLROpoj2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83723 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590890|imex:IM-9152-1920 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0741; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:61B12CB545B1369C|rigid:Po248LXK6YYJzClIB07zf6UquKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83846 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590924|imex:IM-9152-1924 author score:0.633426434 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:3447329E76CD4CF7|rigid:EHFjB0Mr6ez94YI4yGGUfzHag6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83846 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590918|imex:IM-9152-1923 author score:0.70068598 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0803|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:4778EDFD48CE0241|rigid:RHq3gA6l5JDZJ/Vvzew3/JCSNrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83846 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590939|imex:IM-9152-1926 author score:0.571311828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:7543A2A330D65B3B|rigid:wrvg/npOepgei3gsKQAK9HzwCgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83956 uniprotkb:O83846 intact:EBI-1590930|ensemblbacteria:AAC65947 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:rubr_trepa(display_long)|uniprotkb:TP_0991(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590933|imex:IM-9152-1925 author score:0.577760141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018527|ensemblbacteria:AAC65947(transcript)|ensemblbacteria:TP_0991(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|interpro:IPR024922|interpro:IPR024934|interpro:IPR024935|refseq:WP_010882435.1 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0991|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:zn6kAatILy/x8kIkBZ3z/pfLkLc243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:D51B833BC0B97EAC|rigid:bGYDCbhRsD2lPbGBAIEG3lMDCno false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83865 uniprotkb:O83846 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590951|imex:IM-9152-1928 author score:0.564572454 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0895|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:7DB0F2DAE8190C5E|rigid:+yo7xhG/MHwptXfOBE+iJhY9n6s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83846 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590945|imex:IM-9152-1927 author score:0.564572454 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0097|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:A5BF3C2686BEBD2A|rigid:PskIJbyh0BXeQrI+9pnDJpgiH7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83158 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590963|imex:IM-9152-1930 author score:0.537939536 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:C2478CCCEF7FE883|rigid:PHqutmF+YMJL37l2dR0291fMF68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83595 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590957|imex:IM-9152-1929 author score:0.55719891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:4E041B5C10E326EB|rigid:9aV4f3ckzD9JULPUXxWYyGmPZKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83846 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590975|imex:IM-9152-1932 author score:0.477452334 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:017956298FA3DAB0|rigid:vCRSc1gLxJE1/DyrGooXqyT7apc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83846 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590969|imex:IM-9152-1931 author score:0.537939536 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:8AE48CDFBF88FA16|rigid:CHUNcAxSwEmd0/JM3UoPB/am5J8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83738 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590987|imex:IM-9152-1934 author score:0.42019244 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:DBE71159FBECA3C8|rigid:O6/z7GRtqObG8Z8asXRXXPurMHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83846 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590981|imex:IM-9152-1933 author score:0.430770259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:94FE7B319FBC497E|rigid:W2k2wkMpnZQ//RSlhXST4wT70dA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83846 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591005|imex:IM-9152-1937 author score:0.196320315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:D48A979892944E2B|rigid:iibjw+uVKxcokhFc8hT2xbmqWIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83846 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590999|imex:IM-9152-1936 author score:0.262592252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:FCFBA2174CFBF109|rigid:NTJIywJ0xEbSUXJ/A/CdDoUg0I0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83846 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1590993|imex:IM-9152-1935 author score:0.284916202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:189853AE6E7662B0|rigid:2eSj1yGtJuxq7c7i/4gPxqLKFcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83413 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591017|imex:IM-9152-1939 author score:0.061303543 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:B655CDDD772AF781|rigid:vwXd0bzLZP0cCAqJLVxlVX+pdaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83846 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591011|imex:IM-9152-1938 author score:0.103096528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 intact-crc:FFF9C3DF24E4CEE4|rigid:b9clZOWS3VP1O9j7wuYqnADJXTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83954 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591029|imex:IM-9152-1941 author score:0.010926929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:DAEA6EC26B711B62|rigid:wnebEjJMAfTXekQxzD4VkLdCAAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83667 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591023|imex:IM-9152-1940 author score:0.05681715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:3657F48E302C39FD|rigid:bEsby6titabwd77cRqJG6mGL7X0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83983 uniprotkb:O83726 intact:EBI-1586373|ensemblbacteria:AAC65970 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:gata_trepa(display_long)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)|uniprotkb:TP_1020(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591041|imex:IM-9152-1943 author score:0.700683555 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412("Glutamyl-tRNA(Gln) amidotransferase A subunit")|ensemblbacteria:AAC65970(transcript)|ensemblbacteria:TP_1020(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|refseq:WP_010882464.1|interpro:IPR036928 interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_1020|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:M+KheF38jzx6H71RxIAdEJXnNfQ243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:7203C4BDA7FD50A0|rigid:F+EAXBb9fzooFwwHHP/t/a/jY84 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83846 uniprotkb:O83958 intact:EBI-1587311|ensemblbacteria:AAC65839|ensemblbacteria:AGN76045 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83846_trepa(display_long)|uniprotkb:TP_0876(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591035|imex:IM-9152-1942 author score:0.000879563 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022496|interpro:IPR000905(Peptidase M22, glycoprotease)|ensemblbacteria:AAC65839(transcript)|ensemblbacteria:AGN76045(transcript)|ensemblbacteria:TP_0876(gene)|ensemblbacteria:TPANIC_0876(gene)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|interpro:IPR043129|refseq:WP_010882319.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0876; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8QoUW9gcfO8HEcy7eN3AQjlSPFY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D46A3B062ADCF470|rigid:3dT8qc3z8OK4x1BM2X/+s8HfUoM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83726 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591056|imex:IM-9152-1945 author score:0.430407445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:E6A0C713E1C46E66|rigid:NBC7kJfVOewg22T4+XkgmHf+OMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83726 uniprotkb:O83913 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591050|imex:IM-9152-1944 author score:0.622591587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:1864E12C6E34488B|rigid:xcd0wAR6Q0QD+Rlk/yPQ10ZfCYo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83726 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591068|imex:IM-9152-1947 author score:0.252020853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:D697A33CBF977B52|rigid:/6wkcwqkWCsrwwEWDOn7k/m3XpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83726 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591062|imex:IM-9152-1946 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:2A06FEE7A3CC4D45|rigid:FXZNYl9Y9Tql5QKz/RnG8eQyKxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83726 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591074|imex:IM-9152-1948 author score:0.237102582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:78CAE860605E5D48|rigid:3DnhSjWbQlyhxrqfun+6+JNvhWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83726 uniprotkb:O83927 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591080|imex:IM-9152-1949 author score:0.204713982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:21CF90D9C9CFD387|rigid:2f0OxnC/Rpfx5zKXvQCA6haYpHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83726 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591086|imex:IM-9152-1950 author score:0.055314123 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 intact-crc:E67CCAB6ED07BCDD|rigid:aJN5+kzEiL9oVOxy4wBr7ekVdd0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83726 uniprotkb:O83954 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591098|imex:IM-9152-1952 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:DBE9604036D7FF0F|rigid:RVp3pNapjM1LN3GVYg+BwYBPZHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83726 uniprotkb:O83282 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591092|imex:IM-9152-1951 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8452E2599A624A1C|rigid:oOJF+VYwphkWaAEiVJsPPJ3GAC0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83726 uniprotkb:O83958 intact:EBI-1591045|ensemblbacteria:AAC65712|ensemblbacteria:AGN75918 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83726_trepa(display_long)|uniprotkb:TP_0744(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591104|imex:IM-9152-1953 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007422(Protein of unknown function DUF464)|ensemblbacteria:AAC65712(transcript)|ensemblbacteria:AGN75918(transcript)|ensemblbacteria:TP_0744(gene)|ensemblbacteria:TPANIC_0744(gene)|refseq:WP_010882189.1|interpro:IPR036764 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0744; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Mt5xmHxaI0HfkZL/DTD68lJKfQ243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:E12C2C11DBEE1891|rigid:TYtEFSCcnHWQWrYR9+Y6ti9xjQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83242 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1591110|ensemblbacteria:AAC65201 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:rpoa_trepa(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:TP_0212(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591114|imex:IM-9152-1954 author score:0.698521129 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|ensemblbacteria:AAC65201(transcript)|ensemblbacteria:TP_0212(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:WP_010881660.1|interpro:IPR036603|interpro:IPR036643 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0212; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:TEgJZXgJTyijLD+seDCIyZrUUKg243276 intact-crc:FA32B1E65217CF8D|rigid:4m5/0sF2eULpAvghNrs6mC9tTs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83242 uniprotkb:O83099 intact:EBI-1591110|ensemblbacteria:AAC65201 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:rpoa_trepa(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:TP_0212(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591126|imex:IM-9152-1956 author score:0.333073726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|ensemblbacteria:AAC65201(transcript)|ensemblbacteria:TP_0212(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:WP_010881660.1|interpro:IPR036603|interpro:IPR036643 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0212; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TEgJZXgJTyijLD+seDCIyZrUUKg243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:12909FB662254B4E|rigid:ByrkF/LtYb7F1FDH2C9X8FdO8tE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83242 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1591110|ensemblbacteria:AAC65201 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:rpoa_trepa(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:TP_0212(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591120|imex:IM-9152-1955 author score:0.414759643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|ensemblbacteria:AAC65201(transcript)|ensemblbacteria:TP_0212(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|refseq:WP_010881660.1|interpro:IPR036603|interpro:IPR036643 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0212; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:TEgJZXgJTyijLD+seDCIyZrUUKg243276 intact-crc:7BCABC7D65E34BCA|rigid:x5sA2oY3h4aU1e8RzaEyjpjk/Fo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83404 uniprotkb:O83395 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591141|imex:IM-9152-1958 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0380|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:5CDFE540E7527D14|rigid:FsmUv2dxEpal3IAM9hfPuqqt3Zs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83284 uniprotkb:O83404 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591132|imex:IM-9152-1957 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0260|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:DAFF1D4EFCB33958|rigid:y4/9ZYZv7g8vjmFI6cozaZayxWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83404 uniprotkb:O83105 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591162|imex:IM-9152-1961 author score:0.661706315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:487F3E22D4A43460|rigid:Bg7LJDIZE8rHPUhPFh1hLSQvRJY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83588 uniprotkb:O83404 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591150|imex:IM-9152-1959 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0579|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:D25C38109A75FF45|rigid:gghMNd4B9qJnsWXpPg/5cmMC/tc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83404 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591156|imex:IM-9152-1960 author score:0.667706456 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:A41707A5C0679BB6|rigid:Z2vNCrDJK3nVkb9qQkY6LmZxlyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83404 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591168|imex:IM-9152-1962 author score:0.649239945 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:791096359009B931|rigid:zr39mnZUaIEetVg5IKM3iMsShPU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83404 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591174|imex:IM-9152-1963 author score:0.492731272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:BF21C1C7F066C06C|rigid:+nd8QgTmLP7QpQC9pgPDqcBoolc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83404 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591180|imex:IM-9152-1964 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:E338FA98E8668AC2|rigid:7jpRNLEGtNmIZY3OKmBPTSi+OHY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83404 uniprotkb:O83745 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591186|imex:IM-9152-1965 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:6B8582881553AA70|rigid:VOrSB8kiTG8aYoTN3sH8rrm/cKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83404 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591136|ensemblbacteria:AAC65373|ensemblbacteria:AGN75583 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83404_trepa(display_long)|uniprotkb:ftsA(gene name)|psi-mi:ftsA(display_short)|uniprotkb:TP_0389(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591192|imex:IM-9152-1966 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR043129|interpro:IPR020823|interpro:IPR003494(Cell division protein FtsA)|ensemblbacteria:AAC65373(transcript)|ensemblbacteria:AGN75583(transcript)|ensemblbacteria:TP_0389(gene)|ensemblbacteria:TPANIC_0389(gene)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|refseq:WP_010881837.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0389; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:si3xPra4cLrJP+CkeKNyDqCdtZc243276 intact-crc:91FAA97CC371BD9C|rigid:w54O3/5xpdxLIodGYUF7HtdrOQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83758 uniprotkb:O83395 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591201|imex:IM-9152-1967 author score:0.696871088 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0380|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:B69FD0A64B40BA29|rigid:PcxhpiGl7KbJ/8Wap9ODg0OKVyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83373 uniprotkb:O83758 intact:EBI-1582513|ensemblbacteria:AAC65341 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591207|imex:IM-9152-1968 author score:0.67954353 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 intact-crc:D2B3AF4820589293|rigid:jrW85McB3WP5fxF8CPJzY3XYQHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83758 uniprotkb:O83627 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591219|imex:IM-9152-1970 author score:0.579547284 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:515E82E5047442DB|rigid:kCszWiqSwcH5eEra2/LV6mM1TjE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83758 uniprotkb:O83089 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591213|imex:IM-9152-1969 author score:0.667706456 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:E7BD25B52BC7FEAC|rigid:sQjSS4URad+Z2bjV/Z3DbBy0EfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83758 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591231|imex:IM-9152-1972 author score:0.492731272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 intact-crc:1D8300978D52F62B|rigid:C5h/X6T6ShRe5dp48+/wDuT//F8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83758 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591225|imex:IM-9152-1971 author score:0.51291974 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 intact-crc:0480745709C59D98|rigid:D8rdjN2w+XcFNGpvcR+GFuQZQhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83758 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591237|imex:IM-9152-1973 author score:0.322575688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 intact-crc:E49470C3BC33A22D|rigid:ss4JWMEbhdW6qQ1IANKQuMkxEn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83758 uniprotkb:O83574 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591243|imex:IM-9152-1974 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:3170505E5041767B|rigid:Cca2FNQ/RxQcVzLJO64yaRQryUM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83758 uniprotkb:O83877 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591249|imex:IM-9152-1975 author score:0.150881184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:BE86E70022B9EAD1|rigid:Z2hSCDhSuZBCAA7Mh2FF/0HIFnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83758 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1591198|ensemblbacteria:AAC65747|ensemblbacteria:AGN75952 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83758_trepa(display_long)|uniprotkb:TP_0779(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591255|imex:IM-9152-1976 author score:0.08188443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR032816|interpro:IPR032818|ensemblbacteria:AAC65747(transcript)|ensemblbacteria:AGN75952(transcript)|ensemblbacteria:TP_0779(gene)|ensemblbacteria:TPANIC_0779(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882224.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0779; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:bW4P425sk8E0nvWnFcFD1GJgluw243276 intact-crc:BA7135FA22E92F5B|rigid:A2/1GeXUTb+KfBGDmY6C/iDklsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83176 uniprotkb:O83909 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591264|imex:IM-9152-1977 author score:0.696766881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:FFC53668E12F51CB|rigid:5W+Dw7ml7laGEL8hEcvLALMbLzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83176 uniprotkb:O83969 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591270|imex:IM-9152-1978 author score:0.302115441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:657AD2E9C69AEA1F|rigid:Ty4LCWx/xoG00EIiAhnj4pOIPBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83176 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591282|imex:IM-9152-1980 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 intact-crc:F58852C83483C3DC|rigid:glZl3POlZBt5xIwFGQxR7t4UGLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83176 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591276|imex:IM-9152-1979 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 intact-crc:941C7C137EFCE87F|rigid:PfatMKrjeMlFPXCs0jeD4wXUUtM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83176 uniprotkb:O83954 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591294|imex:IM-9152-1982 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:B42C4F4D547061D7|rigid:NXf97GDgq87zd9TvUffRAAf/Su8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83176 uniprotkb:O83745 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591288|imex:IM-9152-1981 author score:0.06996641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:FB307095A815B0C5|rigid:u6hB+XPoio9SVMbXSIFbBv/9Sko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83176 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591261|ensemblbacteria:AAC65128|ensemblbacteria:AGN75360 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83176_trepa(display_long)|uniprotkb:TP_0140(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591300|imex:IM-9152-2328 author score:0.002064733 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003445(Cation transporter)|interpro:IPR004772(Potassium uptake protein TrkH)|ensemblbacteria:AAC65128(transcript)|ensemblbacteria:AGN75360(transcript)|ensemblbacteria:TP_0140(gene)|ensemblbacteria:TPANIC_0140(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881588.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0140; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:rgOQWfXHju3g7FP8Czj7atmk/YQ243276 intact-crc:CD9BA24EEB590E0C|rigid:xoocIGEcRTIX85qLjEGqx9LN5ro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83517 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1586811|ensemblbacteria:AAC65493 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y504_trepa(display_long)|uniprotkb:TP_0504(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591312|imex:IM-9152-2330 author score:0.367817664 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65493(transcript)|ensemblbacteria:TP_0504(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0504; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:n9QSzS7951L1x/g+DzdsDg+Mu/Y243276 intact-crc:12A81EEF3538E5C3|rigid:9NnOfoawPrNxyQLQaEmdqhTMvDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83517 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1586811|ensemblbacteria:AAC65493 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:y504_trepa(display_long)|uniprotkb:TP_0504(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591306|imex:IM-9152-2329 author score:0.696662653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 ensemblbacteria:AAC65493(transcript)|ensemblbacteria:TP_0504(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0504; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:n9QSzS7951L1x/g+DzdsDg+Mu/Y243276 intact-crc:5159AEE6F968DC24|rigid:LgT/+SVRTfl0QCts+PWcHavFIzM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83517 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586811|ensemblbacteria:AAC65493 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y504_trepa(display_long)|uniprotkb:TP_0504(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591324|imex:IM-9152-2332 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65493(transcript)|ensemblbacteria:TP_0504(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0504; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:n9QSzS7951L1x/g+DzdsDg+Mu/Y243276 intact-crc:C33EFF74EB44CCDA|rigid:Y7qipLiINalofnY57VvT0Bxp8k4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83517 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1586811|ensemblbacteria:AAC65493 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y504_trepa(display_long)|uniprotkb:TP_0504(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591318|imex:IM-9152-2331 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65493(transcript)|ensemblbacteria:TP_0504(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0504; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:n9QSzS7951L1x/g+DzdsDg+Mu/Y243276 intact-crc:923587D76BDB4A72|rigid:jndXoYOd3iHKx0GIDAL5ieLK9Mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83885 uniprotkb:P16055 intact:EBI-1591336|ensemblbacteria:AAC65872|ensemblbacteria:AGN76083 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:o83885_trepa(display_long)|uniprotkb:TP_0915(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591339|imex:IM-9152-2334 author score:0.694797727 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65872(transcript)|ensemblbacteria:AGN76083(transcript)|ensemblbacteria:TP_0915(gene)|ensemblbacteria:TPANIC_0915(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|refseq:WP_010882358.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0915; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BWcja6waKf4+RZ8ay/0FQpyXOCQ243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:29ACF0CBD9DCDC31|rigid:RVSSy+/2KnWAGUnPAda6OGuu0nk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83570 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591330|imex:IM-9152-2333 author score:0.696558406 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0559; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:D5A758C6F32C4E67|rigid:fV58xbZNmZaJbo22r/MAEotsieY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83885 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1591336|ensemblbacteria:AAC65872|ensemblbacteria:AGN76083 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83885_trepa(display_long)|uniprotkb:TP_0915(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591351|imex:IM-9152-2336 author score:0.143215719 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65872(transcript)|ensemblbacteria:AGN76083(transcript)|ensemblbacteria:TP_0915(gene)|ensemblbacteria:TPANIC_0915(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|refseq:WP_010882358.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0915; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:BWcja6waKf4+RZ8ay/0FQpyXOCQ243276 intact-crc:B6443C77A931A639|rigid:ZnxarDQte5KVpMCCAn/H+5rbi2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83885 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1591336|ensemblbacteria:AAC65872|ensemblbacteria:AGN76083 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83885_trepa(display_long)|uniprotkb:TP_0915(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591345|imex:IM-9152-2335 author score:0.329171391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65872(transcript)|ensemblbacteria:AGN76083(transcript)|ensemblbacteria:TP_0915(gene)|ensemblbacteria:TPANIC_0915(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|refseq:WP_010882358.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0915; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:BWcja6waKf4+RZ8ay/0FQpyXOCQ243276 intact-crc:956A73DDB814B77E|rigid:0x1+iWxz7GzcpLflhF3wyLtwRS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83885 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591336|ensemblbacteria:AAC65872|ensemblbacteria:AGN76083 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83885_trepa(display_long)|uniprotkb:TP_0915(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591363|imex:IM-9152-2338 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65872(transcript)|ensemblbacteria:AGN76083(transcript)|ensemblbacteria:TP_0915(gene)|ensemblbacteria:TPANIC_0915(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|refseq:WP_010882358.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0915; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:BWcja6waKf4+RZ8ay/0FQpyXOCQ243276 intact-crc:7927EF9408C9BF91|rigid:osPG1OcxQ2KYfEPTyE7+jgLduo4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83885 uniprotkb:O83745 intact:EBI-1591336|ensemblbacteria:AAC65872|ensemblbacteria:AGN76083 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83885_trepa(display_long)|uniprotkb:TP_0915(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591357|imex:IM-9152-2337 author score:0.116537817 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007560(Restriction endonuclease, type IV-like, Mrr)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65872(transcript)|ensemblbacteria:AGN76083(transcript)|ensemblbacteria:TP_0915(gene)|ensemblbacteria:TPANIC_0915(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0009307"(DNA restriction-modification system)|refseq:WP_010882358.1|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0915; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BWcja6waKf4+RZ8ay/0FQpyXOCQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:2A86C4E72189DD24|rigid:BO80Cbxtpz8A4Bi9fOuMA11qvs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83970 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591375|imex:IM-9152-2340 author score:0.523916525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1005; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:708EDFA633FBFEA6|rigid:YejmjZcZZGippBpx9guJzsDRrBY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83970 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591369|imex:IM-9152-2339 author score:0.694797727 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1005; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:5683E20E342791CD|rigid:c/N4fxoXiNBclYSj7zO7Zwqk3oQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83667 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591381|imex:IM-9152-2341 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1005; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:986DA2FAECC94183|rigid:Jm+0g9vzGKW/iffzQIfDDMRA5HQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83970 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591393|imex:IM-9152-2343 author score:0.002147916 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1005; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:CD6CCF49CDA059EF|rigid:OhMOPyV9pngr0pY0f9lMGZMdvqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83970 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591387|imex:IM-9152-2342 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1005; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:E3BCDF390006E864|rigid:MH0s+lWdjA+fY4Za3bCetd/gZ4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83244 uniprotkb:O83884 intact:EBI-1589531|ensemblbacteria:AAC65210 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:y214_trepa(display_long)|uniprotkb:TP_0214(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591411|imex:IM-9152-2345 author score:0.68738031 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65210(transcript)|ensemblbacteria:TP_0214(gene)|refseq:WP_010881662.1 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0214|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HAC6HFUlZSuAKwcd7O49uTZBi/M243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:62A26E9C47135614|rigid:ftHQvQMqpiPNkWK2qmQdPgkMx3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:O83315 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1591402|ensemblbacteria:AAC65283|ensemblbacteria:AGN75496 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:o83315_trepa(display_long)|uniprotkb:TP_0291(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591405|imex:IM-9152-2344 author score:0.693136259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000262(FMN-dependent alpha-hydroxy acid dehydrogenase)|ensemblbacteria:AAC65283(transcript)|ensemblbacteria:AGN75496(transcript)|ensemblbacteria:TP_0291(gene)|ensemblbacteria:TPANIC_0291(gene)|go:"GO:0016491"(oxidoreductase activity)|refseq:WP_010881740.1|interpro:IPR037396 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0291|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:ozXuSbhyOOY2JNr80i/V7CgCdbE243276 intact-crc:5DA0540AFD446D29|rigid:JaV1tivQhv6GpYR+s9g7as5ILiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:O83969 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591423|imex:IM-9152-2347 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:68D2B7F3D982E275|rigid:5QHMGrxKydsv7MYegxS0CeK+FUg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83884 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591417|imex:IM-9152-2346 author score:0.607760467 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:61E03713ABF76FE2|rigid:+Ub/gO97FWWvXTyaaWIZRx/x5+8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83884 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591435|imex:IM-9152-2349 author score:0.159487671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:3E660CFE03B6ADC2|rigid:Xv6lohwHHjXNkaKA1YVi+A1j6rw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:P21992 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591429|imex:IM-9152-2348 author score:0.216678193 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:63CA6CF804F12F4D|rigid:svw5QKkQ5fY/BhhKqNk5AEsM/hY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83884 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591447|imex:IM-9152-2351 author score:0.078405193 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:C549934712FB8C77|rigid:/SbB6d6G9vimBohazVo2L4h0fMk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83884 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591441|imex:IM-9152-2350 author score:0.090447395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:4E5AE4135D814838|rigid:ytiCnVMRLYWat22bX5alkm1CW5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83884 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591459|imex:IM-9152-2353 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 intact-crc:79321ECB8248CAA4|rigid:J2BwthdTKywjBqKg9YdVnuVGClg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:O83767 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591453|imex:IM-9152-2352 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:844FDDB437130F09|rigid:IDV0pjnOxw2HwbM3xuPDEIlzV0c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:O83958 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591471|imex:IM-9152-2355 author score:0.00107844 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:93A6B95B745673DF|rigid:XBKJX3K/bELb9PX/QFOIQyqai4A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83884 uniprotkb:O83954 intact:EBI-1591399|ensemblbacteria:AAC65871|ensemblbacteria:AGN76082 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83884_trepa(display_long)|uniprotkb:TP_0914(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591465|imex:IM-9152-2354 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65871(transcript)|ensemblbacteria:AGN76082(transcript)|ensemblbacteria:TP_0914(gene)|ensemblbacteria:TPANIC_0914(gene)|refseq:WP_010882357.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0914; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sUxMQ/5TFy+v5sjhF6riBTC4Szk243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:C9042390675FE28E|rigid:TDzyCIh7LAneLrdd75Lqvtdqm0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83532 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591490|imex:IM-9152-2357 author score:0.508516923 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:65D04F623274B33A|rigid:vuGkNOBP0P2FDcDX1SMDea+UAF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83842 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1591480|ensemblbacteria:AAC65836 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:flid_trepa(display_long)|uniprotkb:fliD(gene name)|psi-mi:fliD(display_short)|uniprotkb:Filament cap protein(gene name synonym)|uniprotkb:Flagellar cap protein(gene name synonym)|uniprotkb:TP_0872(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591484|imex:IM-9152-2356 author score:0.693136259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 interpro:IPR040026|interpro:IPR010809(Flagellar hook-associated 2, C-terminal)|interpro:IPR003481(Flagellar hook-associated protein 2, N-terminal)|ensemblbacteria:AAC65836(transcript)|ensemblbacteria:TP_0872(gene)|go:"GO:0007155"(cell adhesion)|go:"GO:0009421"(bacterial-type flagellum filament cap)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0055040"(periplasmic flagellum)|refseq:WP_010882315.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0872|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:6f3uV/HnRU2Wfz0sJa7uhHbErV0243276 intact-crc:68D5FAAC8775C01E|rigid:w/jaHRPU7gqkLVV1OXkrpI5WN/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83078 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1591477|ensemblbacteria:AAC65030 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591502|imex:IM-9152-2359 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 intact-crc:37ACDA60B29AEEFD|rigid:n1rXU2vbQcL2Qkpf9wzBMK8IBLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83565 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591496|imex:IM-9152-2358 author score:0.488328011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:F22FD239E810142B|rigid:6OU8YeyXklapcr4r2pzbxvqwOQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83574 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591520|imex:IM-9152-2362 author score:0.159487671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C46BDCA4D9E84BD1|rigid:59H0/7PyKMWsHbbPJYFcYRZ6+s4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83078 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1591477|ensemblbacteria:AAC65030 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591514|imex:IM-9152-2361 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 intact-crc:2D420EAF20DE0E03|rigid:dvS9IkzD1ys5C1hSEfqNa7eiPWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83982 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591508|imex:IM-9152-2360 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:D82B9E1B112C56BC|rigid:Vghf0ump7VXL393Yr4BK6rw7UNU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83078 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1591477|ensemblbacteria:AAC65030 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591532|imex:IM-9152-2364 author score:0.097315309 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 intact-crc:15DFFADA5A60312E|rigid:1jt4Ls1p/lSkeXTKcGxIPCNdcbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83877 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591526|imex:IM-9152-2363 author score:0.143991274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:283C0A224A923C00|rigid:8m4ilAQAkyqyuBJ3aP2epGnkwq0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83078 uniprotkb:O83767 intact:EBI-1591477|ensemblbacteria:AAC65030 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591538|imex:IM-9152-2365 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:EFC75CE50713F7BE|rigid:ss9QsUvpCtUdK63dAxmMl6RMgRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83078 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1591477|ensemblbacteria:AAC65030 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591544|imex:IM-9152-2366 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 intact-crc:443E135839BB97F2|rigid:xU6SOhWevV35jgUEhUCDnl7Ykjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08255 uniprotkb:O83284 intact:EBI-1584220|ensemblbacteria:AAC65647 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591556|imex:IM-9152-2368 author score:0.692926388 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:03F5E9DBDAC2BED9|rigid:RU1RHbtJgz74KUs5oSW2H7SG1nU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83078 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591477|ensemblbacteria:AAC65030 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y035_trepa(display_long)|uniprotkb:TP_0035(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591550|imex:IM-9152-2367 author score:0.00107844 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|ensemblbacteria:AAC65030(transcript)|ensemblbacteria:TP_0035(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881484.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0035; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:0YqmcxouYA0beAJ8wHxi7VwQNXo243276 intact-crc:1E9C89932AB206A3|rigid:JpCLRi0ps9lZHNlqcEysynT/W7I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83284 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591562|imex:IM-9152-2369 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:138C9131179DD5BD|rigid:SuX5XJU+su7zvClwZaAqcTqH2Q0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83284 uniprotkb:O83805 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591574|imex:IM-9152-2371 author score:0.57500693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:2AE147EF04EF0EFA|rigid:GniQtlZp7QZ7kdilEKBaBtHgf8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83284 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591568|imex:IM-9152-2370 author score:0.57500693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:9CF44236AD556EA0|rigid:8Hoaxm11bgp7JGq98swmgA/cPjU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83284 uniprotkb:O83745 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591586|imex:IM-9152-2373 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:96C0CB1FF5E50146|rigid:Ajpr6U7zA/6Fl0Hlb2huL3ubkJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83284 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591580|imex:IM-9152-2372 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0260; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:615ADA7FCFFA6B51|rigid:g8dH97nw5cYZwGi6gG1gAmyBkac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83121 uniprotkb:O83068 intact:EBI-1591596|ensemblbacteria:AAC65079 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591601|imex:IM-9152-2375 author score:0.68716828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:D8B17FCB5FEC9377|rigid:A4Wux56JB/ZXw7kThNTdKG+fJ1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83121 uniprotkb:O83913 intact:EBI-1591596|ensemblbacteria:AAC65079 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591592|imex:IM-9152-2374 author score:0.692926388 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:19B62997C8156EAB|rigid:lZR+9B3YdG+SW+FIoMueHSmiM7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83121 uniprotkb:O83752 intact:EBI-1591596|ensemblbacteria:AAC65079 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591613|imex:IM-9152-2377 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:9C532F884506A144|rigid:Kk0n53tmqnYuJaWmZ+uE37JaryY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83121 uniprotkb:O83596 intact:EBI-1591596|ensemblbacteria:AAC65079 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591607|imex:IM-9152-2376 author score:0.645303091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:0F73024BD5CA66D2|rigid:fJMEjrxdykOrnNDRve93uNbuKtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83121 uniprotkb:O83413 intact:EBI-1591596|ensemblbacteria:AAC65079 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591625|imex:IM-9152-2379 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CBFF2A4205C22AF4|rigid:wm4L3/0QTSfSTqqDBMLEM/s6mhU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83121 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1591596|ensemblbacteria:AAC65079 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83121_trepa(display_long)|uniprotkb:TP_0083(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591619|imex:IM-9152-2378 author score:0.216510799 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR025275|ensemblbacteria:AAC65079(transcript)|ensemblbacteria:TP_0083(gene)|interpro:IPR017853(Glycoside hydrolase, catalytic core) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0083; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ZrkMl29DxJLpXcSMa4xUciT+rMA243276 intact-crc:A5232C06E0B565FE|rigid:/ksmmpFNbL9CJLEnQnFzAAujxbY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83141 uniprotkb:O83667 intact:EBI-1591631|ensemblbacteria:AAC65098|ensemblbacteria:AGN75322 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83141_trepa(display_long)|uniprotkb:TP_0103(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591646|imex:IM-9152-2382 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65098(transcript)|ensemblbacteria:TP_0103(gene)|ensemblbacteria:TPANIC_0103(gene)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|ensemblbacteria:AGN75322(transcript)|refseq:WP_010881552.1|interpro:IPR027417 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0103; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DIDxbLUmWb5LP3G6w7UehLEPztk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:1319FCFC418E0B72|rigid:mxs59CitiujQ1PtLlpjMBozTuPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83141 uniprotkb:O83570 intact:EBI-1591631|ensemblbacteria:AAC65098|ensemblbacteria:AGN75322 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83141_trepa(display_long)|uniprotkb:TP_0103(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591640|imex:IM-9152-2381 author score:0.641146495 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65098(transcript)|ensemblbacteria:TP_0103(gene)|ensemblbacteria:TPANIC_0103(gene)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|ensemblbacteria:AGN75322(transcript)|refseq:WP_010881552.1|interpro:IPR027417 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0103; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DIDxbLUmWb5LP3G6w7UehLEPztk243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:E578B94D962AC512|rigid:9usKxijNnCZotnxax9EUyYy6St8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83141 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1591631|ensemblbacteria:AAC65098|ensemblbacteria:AGN75322 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83141_trepa(display_long)|uniprotkb:TP_0103(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591634|imex:IM-9152-2380 author score:0.691751178 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65098(transcript)|ensemblbacteria:TP_0103(gene)|ensemblbacteria:TPANIC_0103(gene)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|ensemblbacteria:AGN75322(transcript)|refseq:WP_010881552.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0103; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:DIDxbLUmWb5LP3G6w7UehLEPztk243276 intact-crc:61A23953EB7A9ED2|rigid:SbnC+vk/4juDnMtiUa710jq+e10 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83141 uniprotkb:O83958 intact:EBI-1591631|ensemblbacteria:AAC65098|ensemblbacteria:AGN75322 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83141_trepa(display_long)|uniprotkb:TP_0103(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591658|imex:IM-9152-2384 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65098(transcript)|ensemblbacteria:TP_0103(gene)|ensemblbacteria:TPANIC_0103(gene)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|ensemblbacteria:AGN75322(transcript)|refseq:WP_010881552.1|interpro:IPR027417 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0103; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DIDxbLUmWb5LP3G6w7UehLEPztk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:AB93CAC02AC8CE28|rigid:6uFe2D69/RWNzUp0a8emAHeSMR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83141 uniprotkb:O83745 intact:EBI-1591631|ensemblbacteria:AAC65098|ensemblbacteria:AGN75322 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83141_trepa(display_long)|uniprotkb:TP_0103(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591652|imex:IM-9152-2383 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65098(transcript)|ensemblbacteria:TP_0103(gene)|ensemblbacteria:TPANIC_0103(gene)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|ensemblbacteria:AGN75322(transcript)|refseq:WP_010881552.1|interpro:IPR027417 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0103; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DIDxbLUmWb5LP3G6w7UehLEPztk243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:D7E0B903A410B61D|rigid:kzs4XY3Kv5Ymv+ImU78P6UDsDkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83771 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1591668|ensemblbacteria:AAC65766 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591664|imex:IM-9152-2385 author score:0.691048678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 intact-crc:7995A1B39F14D4D9|rigid:0Uex5D1JWHThs8gc80yWM90jPfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83771 uniprotkb:O83767 intact:EBI-1591668|ensemblbacteria:AAC65766 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591685|imex:IM-9152-2388 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:401FDED57C9765B6|rigid:xEWgYB44q+UZZS2dzTSDRmUZn1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83771 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1591668|ensemblbacteria:AAC65766 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591679|imex:IM-9152-2387 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 intact-crc:C929F1B1925840FA|rigid:0y8ifcjdeIAN4HFLazih9fLSUQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83771 uniprotkb:O83805 intact:EBI-1591668|ensemblbacteria:AAC65766 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591673|imex:IM-9152-2386 author score:0.559628514 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:C8771238B6D0FC43|rigid:Pc9TcaHAqE0zgxJPHMqUx5leRds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83771 uniprotkb:O83282 intact:EBI-1591668|ensemblbacteria:AAC65766 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591691|imex:IM-9152-2389 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:A29602100676D5A7|rigid:suc6HtWhy7f4f20N3Y6FEdBtTF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83771 uniprotkb:O83958 intact:EBI-1591668|ensemblbacteria:AAC65766 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591703|imex:IM-9152-2391 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:CD877421C86BFB74|rigid:Q6qNQPBVcROVUJZed45rIlQVFdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83771 uniprotkb:O83954 intact:EBI-1591668|ensemblbacteria:AAC65766 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y793_trepa(display_long)|uniprotkb:TP_0793(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591697|imex:IM-9152-2390 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65766(transcript)|ensemblbacteria:TP_0793(gene)|refseq:WP_010882238.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0793; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aj6DVYdmY0rtQxRtR6ptpPF/zIY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:B89507B42AA64AB0|rigid:uHdNgWUglfOmo6ogSI5l3lHhnlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83619 uniprotkb:O83239 intact:EBI-1585533|ensemblbacteria:AAC65586|ensemblbacteria:AGN75791 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o83619_trepa(display_long)|uniprotkb:TP_0610(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591709|imex:IM-9152-2392 author score:0.690838016 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|refseq:WP_010882056.1|ensemblbacteria:AAC65586(transcript)|ensemblbacteria:AGN75791(transcript)|ensemblbacteria:TP_0610(gene)|ensemblbacteria:TPANIC_0610(gene) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0610; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dqO6wT1ywWuAFOW36caK/OfV0E0243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:B671136E4E34FCAA|rigid:/nZ9J6QUGXjRZfJPFg3rG+Md5VQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83895 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1583951|ensemblbacteria:AAC65882 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:flav_trepa(display_long)|uniprotkb:fldA(gene name)|psi-mi:fldA(display_short)|uniprotkb:TP_0925(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591715|imex:IM-9152-2393 author score:0.690838016 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR010087(Flavodoxin, short chain)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR001226(Flavodoxin, conserved site)|ensemblbacteria:AAC65882(transcript)|ensemblbacteria:TP_0925(gene)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|refseq:WP_010882368.1|interpro:IPR029039 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0925; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:sjn5lih40bMPlilJS+bcmuaqFls243276 intact-crc:C1667EAB19584F63|rigid:JYcmjD8U2/18rmBG4f8XOldRraw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83480 uniprotkb:O83931 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591733|imex:IM-9152-2395 author score:0.685271352 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:F1BAEF7EADED99DD|rigid:vTrJuQ+oSL8x5OmkQ4FPmKKdO6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83896 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1591725|ensemblbacteria:AAC65883|ensemblbacteria:AGN76093 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83896_trepa(display_long)|uniprotkb:TP_0926(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591721|imex:IM-9152-2394 author score:0.690838016 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR000223(Peptidase S26A, signal peptidase I)|interpro:IPR019757|ensemblbacteria:AAC65883(transcript)|ensemblbacteria:AGN76093(transcript)|ensemblbacteria:TP_0926(gene)|ensemblbacteria:TPANIC_0926(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882369.1|interpro:IPR036286|interpro:IPR019533 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0926; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:W4tFsrtsIiJ5JGq5Uzna1KC+K3A243276 intact-crc:6CB5B0B6CB47817D|rigid:re/M+z4Rvao+GEjGwORPFCuxTcM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83480 uniprotkb:O83398 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591745|imex:IM-9152-2397 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:1EDACBF2DC7F9619|rigid:BMoPbPPAyqfPqspG/ZX7DolO0nw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83480 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591739|imex:IM-9152-2396 author score:0.605422711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 intact-crc:F43F5C831DCF930C|rigid:04y4VyA0uHBVXp/ov+5ZxmFkrYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83480 uniprotkb:O83667 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591757|imex:IM-9152-2399 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:0CBD0511633D7024|rigid:/oJKJYCzlIvl9zY2aZ7R8mRqTA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83480 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591751|imex:IM-9152-2398 author score:0.302115441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 intact-crc:FDDBABEBDB5B7244|rigid:4ToDaDev7ioLLtImZeEiZ5h3l6o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83480 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591763|imex:IM-9152-2400 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 intact-crc:2C8D364F49B1F98C|rigid:IHJRYnmWX2rvhFMYtXGyhSYOCF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83480 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591769|imex:IM-9152-2401 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0467; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 intact-crc:599F45DAAB7C4848|rigid:rBOHBx/fBGgo8oRXlV4tBu0ayww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83257 uniprotkb:O83745 intact:EBI-1591779|ensemblbacteria:AAC65215|ensemblbacteria:AGN75442 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83257_trepa(display_long)|uniprotkb:TP_0229(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591784|imex:IM-9152-2403 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005273(Phage SPO1 DNA polymerase-related protein)|interpro:IPR005122(Uracil-DNA glycosylase-like)|ensemblbacteria:AAC65215(transcript)|ensemblbacteria:AGN75442(transcript)|ensemblbacteria:TP_0229(gene)|ensemblbacteria:TPANIC_0229(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR036895 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0229; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6Cxs8CkmEopTptM4OgVk+GyjqQY243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:45404367965103FA|rigid:W4KrLM+7RiEq8xtroULynvtRhCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83257 uniprotkb:O66107 intact:EBI-1591779|ensemblbacteria:AAC65215|ensemblbacteria:AGN75442 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83257_trepa(display_long)|uniprotkb:TP_0229(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591775|imex:IM-9152-2402 author score:0.685164959 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005273(Phage SPO1 DNA polymerase-related protein)|interpro:IPR005122(Uracil-DNA glycosylase-like)|ensemblbacteria:AAC65215(transcript)|ensemblbacteria:AGN75442(transcript)|ensemblbacteria:TP_0229(gene)|ensemblbacteria:TPANIC_0229(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR036895 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0229; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6Cxs8CkmEopTptM4OgVk+GyjqQY243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:1CDAF100877A8925|rigid:Re7nDRuoA88aejapSMfDGS5tldA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83909 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591802|imex:IM-9152-2406 author score:0.683368222 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:7834BBCA662460B1|rigid:RWl3JWS58xlsDfVFMWwOtiA4zJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83257 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591779|ensemblbacteria:AAC65215|ensemblbacteria:AGN75442 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83257_trepa(display_long)|uniprotkb:TP_0229(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591796|imex:IM-9152-2405 author score:0.002519196 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005273(Phage SPO1 DNA polymerase-related protein)|interpro:IPR005122(Uracil-DNA glycosylase-like)|ensemblbacteria:AAC65215(transcript)|ensemblbacteria:AGN75442(transcript)|ensemblbacteria:TP_0229(gene)|ensemblbacteria:TPANIC_0229(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR036895 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0229; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:6Cxs8CkmEopTptM4OgVk+GyjqQY243276 intact-crc:14EFF649BB207130|rigid:5VeBz+MCZ/DT0DJUpFRHl3O/RTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83257 uniprotkb:O83282 intact:EBI-1591779|ensemblbacteria:AAC65215|ensemblbacteria:AGN75442 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83257_trepa(display_long)|uniprotkb:TP_0229(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591790|imex:IM-9152-2404 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005273(Phage SPO1 DNA polymerase-related protein)|interpro:IPR005122(Uracil-DNA glycosylase-like)|ensemblbacteria:AAC65215(transcript)|ensemblbacteria:AGN75442(transcript)|ensemblbacteria:TP_0229(gene)|ensemblbacteria:TPANIC_0229(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR036895 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0229; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6Cxs8CkmEopTptM4OgVk+GyjqQY243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:6AD055C242577F56|rigid:uDoJ97KsGR3g1AkpfdsUYtcoxZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:Q08255 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591808|imex:IM-9152-2407 author score:0.665639147 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:F06D6A766D7396A7|rigid:/1+tEiHcIgSABLDfY/SvLUTfSAs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83709 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591814|imex:IM-9152-2408 author score:0.463547325 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:FD545C8EB5F4472D|rigid:bITEYsogmd7kHMCVKbOqOAxErBY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83767 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591826|imex:IM-9152-2410 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:97404D00C8047E1E|rigid:Yp9COs2xIELMl1jZqNHmFdZgA98 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83413 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591820|imex:IM-9152-2409 author score:0.121660562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:A412224B26F69A0C|rigid:fT4C4dBt6wXZ3/F34nlWzTT5cQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83954 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591838|imex:IM-9152-2412 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1B042E40AF787FBA|rigid:17OSYm+l7ce965hJo5u96vYz1cI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83282 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591832|imex:IM-9152-2411 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:091E1354CBEFFD7F|rigid:JezEi1yDamrZB6G1MsJ60MHiDxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83789 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1583765|ensemblbacteria:AAC65785 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:y813_trepa(display_long)|uniprotkb:TP_0813(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591850|imex:IM-9152-2414 author score:0.681565996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 ensemblbacteria:AAC65785(transcript)|ensemblbacteria:TP_0813(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0813|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:wL71DWwNtjOq2v6Bj7n8xyMImTI243276 intact-crc:B811511AEB8B8809|rigid:IkGH+qX41QJK1dqdFgxYVNK0wvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83958 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591844|imex:IM-9152-2413 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0751; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7D6D4463999A3A08|rigid:PZN7iM6I0ZPfSoqLf/jHByf4b7g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:P16055 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591865|imex:IM-9152-2416 author score:0.594852717 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 intact-crc:2630AEAA189DDEC2|rigid:sniIsV2f5dwPqembYHrxC8sDKB4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83732 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591859|imex:IM-9152-2415 author score:0.657751009 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 intact-crc:2C53BCAC4A0260C1|rigid:2bXadL7A10IIDH9BEICHwhXMkIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83783 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1591854|ensemblbacteria:AAC65772 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591877|imex:IM-9152-2418 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 intact-crc:FE943F763A51CDAB|rigid:D+RiYFFzefma88+yxsF7uLI3mwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83805 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591871|imex:IM-9152-2417 author score:0.481603579 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:FBAFBD63151735CA|rigid:YtfFhCq4iE4tt0y8HowFRxhTyxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83783 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1591854|ensemblbacteria:AAC65772 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591883|imex:IM-9152-2419 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 intact-crc:ADC4EBD91EA4EFE9|rigid:4oe+KYu9CzOt/QYzd++4GLxy+2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83969 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591889|imex:IM-9152-2420 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:E5603A534E3B8CD3|rigid:Jw8gaA2sT7uUdwuvS+tfkeCm/5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83667 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591895|imex:IM-9152-2421 author score:0.090447395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C9A81F60B8260498|rigid:Ef+Mws4LN+pY+4V16l7B9t2xOlg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83783 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1591854|ensemblbacteria:AAC65772 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591907|imex:IM-9152-2423 author score:0.052129895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 intact-crc:E84B42E565A770E3|rigid:vAveubm83nVan8wZlOAO3lIoSfA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83783 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1591854|ensemblbacteria:AAC65772 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591901|imex:IM-9152-2422 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 intact-crc:03BD26C7D2B443A9|rigid:UmDSKgPW0RdNcDji+hz6gqoCxyw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83783 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1591854|ensemblbacteria:AAC65772 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591919|imex:IM-9152-2425 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 intact-crc:2B8832B6DF314465|rigid:VPNKSacSGFx+ulzYcvd5ljczdVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83783 uniprotkb:O83282 intact:EBI-1591854|ensemblbacteria:AAC65772 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83783_trepa(display_long)|uniprotkb:TP_0805(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591913|imex:IM-9152-2424 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001900(Ribonuclease II and R)|ensemblbacteria:AAC65772(transcript)|ensemblbacteria:TP_0805(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036388 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0805; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OR/M12Ng/VVxSdaMsTthLFoaeVc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:FEC0E5B867EF8604|rigid:XMnFM8GhNNGbyLX8vVyB19Gcnvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83261 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591934|imex:IM-9152-2427 author score:0.677514296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:01048A310BFF6157|rigid:+g3cPVyPS6Ag4Er5GhSVvNxdetM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83342 uniprotkb:O83572 intact:EBI-1591925|ensemblbacteria:AAC65310|ensemblbacteria:AGN75522 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83342_trepa(display_long)|uniprotkb:TP_0322(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591928|imex:IM-9152-2426 author score:0.679644825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001851(Bacterial inner-membrane translocator)|ensemblbacteria:AAC65310(transcript)|ensemblbacteria:AGN75522(transcript)|ensemblbacteria:TP_0322(gene)|ensemblbacteria:TPANIC_0322(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010881770.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0322; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:zxomiDomc4JTVER7nu1OjcwT9NM243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:5CF85A036D5A2029|rigid:zbXdY4e5AMx2KIcSWKAw7+CW8EM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83682 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1585709|ensemblbacteria:AAC65652 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591940|imex:IM-9152-2428 author score:0.671604151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 intact-crc:EE9169036F9F3461|rigid:p/RwV7wD6z8NZA7ITxLt/wc1aac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83099 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591946|imex:IM-9152-2429 author score:0.267451934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:D409F57BA7FFF7D2|rigid:f3bpA58+gFwdwGJkE9H1ejqV1II false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83682 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1585709|ensemblbacteria:AAC65652 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591952|imex:IM-9152-2430 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 intact-crc:714A5086E5098C8E|rigid:to6ilVwmUu4w5pHvDvg9iVIyg/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83954 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591970|imex:IM-9152-2433 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:B1C3FF67A10B3188|rigid:auC9i74Ld9JOIIqNW+TDceZmN1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83877 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591964|imex:IM-9152-2432 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:3FBDF9B22B8A49AE|rigid:b8oHBkhfIAQ4J7wyKcSX0+YcClQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83682 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1585709|ensemblbacteria:AAC65652 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591958|imex:IM-9152-2431 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 intact-crc:5458FEEFC23A0559|rigid:7Tv0YRa5Iu+IVYd2oE4vjpugU00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88138 uniprotkb:O83239 intact:EBI-1584653|ensemblbacteria:AAC65107|ensemblbacteria:AAC65117|ensemblbacteria:AGN75353|ensemblbacteria:AGN75336 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o88138_trepa(display_long)|uniprotkb:TP_0117(locus name)|uniprotkb:TP_0131(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591982|imex:IM-9152-2435 author score:0.677298715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65107(transcript)|ensemblbacteria:AAC65117(transcript)|ensemblbacteria:AGN75336(transcript)|ensemblbacteria:AGN75353(transcript)|ensemblbacteria:TP_0117(gene)|ensemblbacteria:TP_0131(gene)|ensemblbacteria:TPANIC_0117(gene)|ensemblbacteria:TPANIC_0131(gene)|refseq:WP_010881566.1 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0117; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E3rUnbUNBCn31ZBDe9ej3SZrZRo243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:33BDFE1DF559369F|rigid:wzbkQXZ3nxUseA+Ct46N0oJ8TGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83682 uniprotkb:O83958 intact:EBI-1585709|ensemblbacteria:AAC65652 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y676_trepa(display_long)|uniprotkb:TP_0676(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591976|imex:IM-9152-2434 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65652(transcript)|ensemblbacteria:TP_0676(gene)|refseq:WP_010882121.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0676; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vPuOM6mfcNF1UQcb+4I+Sj6xHL4243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D7AA954497E9743A|rigid:bpfDgr5Hjp04ALW9OizbeKzfSGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83621 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1591994|ensemblbacteria:AAC65588|ensemblbacteria:AGN75793 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83621_trepa(display_long)|uniprotkb:TP_0612(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591997|imex:IM-9152-2437 author score:0.677298715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|ensemblbacteria:AAC65588(transcript)|ensemblbacteria:AGN75793(transcript)|ensemblbacteria:TP_0612(gene)|ensemblbacteria:TPANIC_0612(gene)|go:"GO:0016226"(iron-sulfur cluster assembly)|refseq:WP_010882058.1|interpro:IPR037284 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0612; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:6j8iK7axBWhtHxDU2wRivWMFlDM243276 intact-crc:D8D942E8E3940512|rigid:hFgHGMeKfeRjDMNfVBDfQhW3vkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88138 uniprotkb:O83767 intact:EBI-1584653|ensemblbacteria:AAC65107|ensemblbacteria:AAC65117|ensemblbacteria:AGN75353|ensemblbacteria:AGN75336 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o88138_trepa(display_long)|uniprotkb:TP_0117(locus name)|uniprotkb:TP_0131(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1591988|imex:IM-9152-2436 author score:0.110516645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65107(transcript)|ensemblbacteria:AAC65117(transcript)|ensemblbacteria:AGN75336(transcript)|ensemblbacteria:AGN75353(transcript)|ensemblbacteria:TP_0117(gene)|ensemblbacteria:TP_0131(gene)|ensemblbacteria:TPANIC_0117(gene)|ensemblbacteria:TPANIC_0131(gene)|refseq:WP_010881566.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0117; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E3rUnbUNBCn31ZBDe9ej3SZrZRo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E6908C543CBA26D6|rigid:CjkgYfICPHlufP7uB/wETYaYGeo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96120 uniprotkb:P45685 intact:EBI-1592013|uniprotkb:Q7DFP9 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592009|imex:IM-9152-2439 author score:0.675478348 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:2BFD1A1506D6FAD7|rigid:7XHv5ILJH44XerxkEZsnPAbpzzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83621 uniprotkb:O83958 intact:EBI-1591994|ensemblbacteria:AAC65588|ensemblbacteria:AGN75793 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83621_trepa(display_long)|uniprotkb:TP_0612(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592003|imex:IM-9152-2438 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010231(SUF system FeS cluster assembly, SufB)|interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|ensemblbacteria:AAC65588(transcript)|ensemblbacteria:AGN75793(transcript)|ensemblbacteria:TP_0612(gene)|ensemblbacteria:TPANIC_0612(gene)|go:"GO:0016226"(iron-sulfur cluster assembly)|refseq:WP_010882058.1|interpro:IPR037284 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0612; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6j8iK7axBWhtHxDU2wRivWMFlDM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6A40D6784C8BEBE5|rigid:+RFtOcE7PtajnE3mHETdQ16KPTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96120 uniprotkb:O83312 intact:EBI-1592013|uniprotkb:Q7DFP9 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592025|imex:IM-9152-2441 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:907CDF9828699E3D|rigid:z6IPXJIhyXDvK/FmzfQFcUGs/T0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:P96120 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1592013|uniprotkb:Q7DFP9 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592019|imex:IM-9152-2440 author score:0.555160027 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 intact-crc:0E0FA4173F8EC462|rigid:mg3611UcsGNt7bemyK8ruBEtsAQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:P96120 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1592013|uniprotkb:Q7DFP9 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592037|imex:IM-9152-470 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 intact-crc:A4E65784C52A7247|rigid:MvYJ5KErW39SytbL4aNSZiCJNgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96120 uniprotkb:O83927 intact:EBI-1592013|uniprotkb:Q7DFP9 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592031|imex:IM-9152-2442 author score:0.260414641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:D636606573FA5C63|rigid:Ha3eqVvb2QQiFJQXxHiBIfQNlfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83405 uniprotkb:P45685 intact:EBI-1592053|ensemblbacteria:AAC65374 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592049|imex:IM-9152-11 author score:0.675478348 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:CE5A706342ECB0E8|rigid:diplLOqnuMZUvLqhXzEAM/bUo14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P96120 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1592013|uniprotkb:Q7DFP9 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592043|imex:IM-9152-10 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0167; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 intact-crc:2AE8955D2DE9C476|rigid:kvYkzu8k65OqQ18qhebcqzyvy5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83405 uniprotkb:O83099 intact:EBI-1592053|ensemblbacteria:AAC65374 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592059|imex:IM-9152-12 author score:0.382179455 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:265E50951A74C717|rigid:XZyyduAiPp0xL8iqqLn+UKI70xQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83405 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1592053|ensemblbacteria:AAC65374 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592077|imex:IM-9152-15 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 intact-crc:51DD9C91C092B5CA|rigid:/b91C+a4bPZxaUcC18pX3S4jSTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83405 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1592053|ensemblbacteria:AAC65374 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592071|imex:IM-9152-14 author score:0.257333324 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 intact-crc:A3B9B4E582251CE0|rigid:MB3Z+mPh5aK4jGcAiS3108DTRTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83405 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1592053|ensemblbacteria:AAC65374 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592065|imex:IM-9152-13 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 intact-crc:D52DBCEDD123219E|rigid:zWUtBC32h4DEpbjBcOzBKjHxg90 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83405 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1592053|ensemblbacteria:AAC65374 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:ftsz_trepa(display_long)|uniprotkb:ftsZ(gene name)|psi-mi:ftsZ(display_short)|uniprotkb:TP_0390(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592083|imex:IM-9152-16 author score:0.002698696 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR020805|interpro:IPR000158(Cell division protein FtsZ, N-terminal)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR018316|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR024757|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051258"(protein polymerization)|go:"GO:0005737"(cytoplasm)|ensemblbacteria:AAC65374(transcript)|ensemblbacteria:TP_0390(gene)|go:"GO:0000917"(division septum assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|refseq:WP_010881838.1|interpro:IPR036525 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0390; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:oJeI8H4VTdUC3KrdGrm4yX5Pqbo243276 intact-crc:EF05F30CA09EE577|rigid:ZoY0IH0h8OLLzkoxiytlFP54pJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83709 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592095|imex:IM-9152-18 author score:0.526113444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0587; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:CE55C114CFA64004|rigid:6ICuLglbUfgIm7bUwjsKpcD+YHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83596 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592089|imex:IM-9152-17 author score:0.673435743 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0587; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:BEE8C1925545706C|rigid:BEvdsdEEv9VfJmYNgneXTaK/7EI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83596 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592107|imex:IM-9152-20 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0587; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:B2A0D584B7996585|rigid:I10lOlgLnB9DJb4cXU3AB+4L/c0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83596 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592101|imex:IM-9152-19 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0587; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:D745306BB4B09A5A|rigid:v9LnlE0UVpYZzfsOpWdMSZ77sH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83474 uniprotkb:O83654 intact:EBI-1584186|ensemblbacteria:AAC65454|ensemblbacteria:AGN75655 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83474_trepa(display_long)|uniprotkb:TP_0461(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592128|imex:IM-9152-23 author score:0.621417109 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65454(transcript)|ensemblbacteria:AGN75655(transcript)|ensemblbacteria:TP_0461(gene)|ensemblbacteria:TPANIC_0461(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881910.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0461|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FfbL2qyGrSt2UWRgwcMrwgMFpNc243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:57C5D698214A4701|rigid:aWRICBWPq1Lffh7ZHOjxsHMo930 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83946 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592122|imex:IM-9152-22 author score:0.672996519 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0981|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 intact-crc:9996F9E372485867|rigid:Z20vmDyF1SryM5Y0vqes5N2m7iw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83075 uniprotkb:O83532 intact:EBI-1592113|ensemblbacteria:AAC65027 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:rsme_trepa(display_long)|uniprotkb:rsmE(gene name)|psi-mi:rsmE(display_short)|uniprotkb:16S rRNA m3U1498 methyltransferase(gene name synonym)|uniprotkb:TP_0032(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592116|imex:IM-9152-21 author score:0.673327256 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006700(Protein of unknown function DUF558, methyltransferase predicted)|ensemblbacteria:AAC65027(transcript)|ensemblbacteria:TP_0032(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:WP_010881481.1|interpro:IPR029026|interpro:IPR029028 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0032; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3iuFSebMHTVA76XrDetTC5ptj4A243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:CD22A3B31E5D055A|rigid:G5LfCxQgreMMDM1MbdgspGU1ZD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83373 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592140|imex:IM-9152-25 author score:0.520691519 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:3C97565D9CEADD8C|rigid:fooxtdhErGEXMZ0iymwOiW12vMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83654 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592134|imex:IM-9152-24 author score:0.54118865 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:CDCFB91A645E2B0E|rigid:J3zfKxwcwZejmn9bVsRCNjOsvcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83527 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581703|ensemblbacteria:AAC65502 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592155|imex:IM-9152-27 author score:0.41630558 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 intact-crc:76667FBED175C91C|rigid:8F8Wdp91Cg+IWy1mU7Ib4hEGJEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83526 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1592146|ensemblbacteria:AAC65501|ensemblbacteria:AGN75702 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83526_trepa(display_long)|uniprotkb:TP_0513(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592149|imex:IM-9152-26 author score:0.435586021 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|ensemblbacteria:AAC65501(transcript)|ensemblbacteria:AGN75702(transcript)|ensemblbacteria:TP_0513(gene)|ensemblbacteria:TPANIC_0513(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|refseq:WP_010881962.1|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0513|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:a4ai6430LAmmKePJdR/ZjwQF/H0243276 intact-crc:B762A641566E2898|rigid:1/au0hxBt74haSVe8nT2OXtzjDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83909 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592170|imex:IM-9152-29 author score:0.362619145 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:2919D589002DA7A4|rigid:qQtGAcCudTceUhmfZ9Fd3nYwRD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83962 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1592165|ensemblbacteria:AAC26585 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592161|imex:IM-9152-28 author score:0.387858147 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 intact-crc:7C6C6FE1261CA6BC|rigid:dFypIcWV3CfTdyRnStgeeCH/Afs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83654 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592182|imex:IM-9152-31 author score:0.334880992 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:062B65E238792919|rigid:iRd/ypQ58Awr0EagL+Knhv+CXfo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83654 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592176|imex:IM-9152-30 author score:0.358434488 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:104CC8B755CECAF1|rigid:R2DotoD2dIAMnFQJxyzEMhZL+50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83865 uniprotkb:O83654 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592200|imex:IM-9152-34 author score:0.32240642 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0895|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:A61BC178E5C8EB67|rigid:nXB5jXpG5eQNxiYAGoQQTBoz1is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83913 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592194|imex:IM-9152-33 author score:0.323413057 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:C6E962F1283C9B44|rigid:PXCBTuqT8Hccb4NdBxpd2FC1HHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83591 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1584735|ensemblbacteria:AAC65556|ensemblbacteria:AGN75768 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83591_trepa(display_long)|uniprotkb:TP_0582(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592188|imex:IM-9152-32 author score:0.33428009 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC65556(transcript)|ensemblbacteria:AGN75768(transcript)|ensemblbacteria:TP_0582(gene)|ensemblbacteria:TPANIC_0582(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025857|refseq:WP_010882028.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0582|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:sIqK+Gq7VqPjw1lTwwblsXbstvA243276 intact-crc:1E7ABD3536FE3D16|rigid:WvTREq9ryMJN9s+8AUxR2aIyeK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83457 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592212|imex:IM-9152-36 author score:0.305020752 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:217B55DF662C32CC|rigid:NrEsiNeoy7vB9/LPUJ4mTy1Gibs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83654 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592206|imex:IM-9152-35 author score:0.315901073 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:23C0008A42944A0F|rigid:64yNx+va3wGDZ0ENs6itE9g9eoI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83239 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592224|imex:IM-9152-38 author score:0.275308969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:78ABA59E8490962D|rigid:tdk6Gbc7wE6gKgVeEUyXMRxHAnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83565 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592218|imex:IM-9152-37 author score:0.284605015 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:9EADF3D41BA09EBB|rigid:IrcmXUTdsEzYPNp6z0Ljy3l/pG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83227 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592242|imex:IM-9152-41 author score:0.256201779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:E103A61EBA30ABE7|rigid:CZfZLO7wp8wWr6Ms8SresP+gqt0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83133 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592236|imex:IM-9152-40 author score:0.256201779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:5060853B252CF784|rigid:sBnbVcFamgHP1vOhn0QsMXVaskE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83361 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592230|imex:IM-9152-39 author score:0.271893471 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:E54558899094BCD0|rigid:UPgw0Wwx/e4N709wk06iN0SzUtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O66107 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592254|imex:IM-9152-43 author score:0.226647447 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:9DF87F5014CB4AE9|rigid:gsxIliWLC+XpF2CXqdKfKbLtKyQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83459 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592248|imex:IM-9152-42 author score:0.240912544 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:CC155A61EA9B1FB0|rigid:QO1ciQTPdEc1qJUr/sLwEaQ0SZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83970 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592266|imex:IM-9152-45 author score:0.19320097 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:EE78069E6EC7EA92|rigid:npOzikss4vdsigcUY/GA9eixkBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83939 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592260|imex:IM-9152-44 author score:0.217348703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:EF84FF4E7916086F|rigid:xy+ttqNPQveCd+UNR031WOrApFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83654 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592278|imex:IM-9152-47 author score:0.14535216 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:23C2971F4F0BC526|rigid:GcmglGm9zYKr6CiKmKPN7l5VRac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83887 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592272|imex:IM-9152-46 author score:0.173625715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:FBCA5886FEA53B0F|rigid:kN+DXx164yUMcUEaV9Oq+yMdHSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83969 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592296|imex:IM-9152-50 author score:0.088639021 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:64029E46F51EFF23|rigid:Rr51nBBgczaI5udWz9fhk8rr2zI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83982 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592290|imex:IM-9152-49 author score:0.110262303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:F22A9E3E6DA18A2C|rigid:AwLehTDTghBhsAbAx4jt0oz33xA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83463 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592284|imex:IM-9152-48 author score:0.115575455 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:234C5FF0155BED07|rigid:n52tKXE99njE6D0KXV9SeXTiqBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83877 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592308|imex:IM-9152-52 author score:0.050416466 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C9B160D9B1394F94|rigid:j7SBjQ/BdV9hLq6C14BaVFrycn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83099 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592302|imex:IM-9152-51 author score:0.087487341 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:BF3BACD346C56871|rigid:IHQD6/PvOQiYg/gA4cEbtugogZQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83654 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592320|imex:IM-9152-54 author score:0.018388801 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:348A66196310A99C|rigid:659/kQ7T/135x1uxUN5VEes05e8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83574 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592314|imex:IM-9152-53 author score:0.040474856 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:78A9BF4029F56BDC|rigid:JwVjxtc5ARRNyU6It+eOQVWKnko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83654 uniprotkb:O83954 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592332|imex:IM-9152-56 author score:0.004037785 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:C5DB446F72144F18|rigid:jezTGKtqLf1Rq83J+KsmfbCU20g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83654 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592326|imex:IM-9152-55 author score:0.004871085 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:4860030E01DDEEC5|rigid:v8ZYX6o1t1O0SmKLJDsOpaFj638 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83081 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1592348|ensemblbacteria:AAC65040 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:y039_trepa(display_long)|uniprotkb:TP_0039(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592344|imex:IM-9152-58 author score:0.671495353 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65040(transcript)|ensemblbacteria:TP_0039(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0039; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:8xb0ZAjIxX2YZcGMDcGgvM/3qMo243276 intact-crc:2D189ACBE92B496A|rigid:9mcIphSyuzdbn6jpt2E25qCxaCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83654 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592338|imex:IM-9152-57 author score:0.000332312 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0648; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:C3F15ADF28F0FD01|rigid:j19USK9r1twK8n79SF8xMXjn2Wg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83081 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1592348|ensemblbacteria:AAC65040 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y039_trepa(display_long)|uniprotkb:TP_0039(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592365|imex:IM-9152-61 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65040(transcript)|ensemblbacteria:TP_0039(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0039; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:8xb0ZAjIxX2YZcGMDcGgvM/3qMo243276 intact-crc:55E9E0827855BA86|rigid:XNbII+CU1ss3k+i6JhAQOm09F9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83081 uniprotkb:O83767 intact:EBI-1592348|ensemblbacteria:AAC65040 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y039_trepa(display_long)|uniprotkb:TP_0039(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592359|imex:IM-9152-60 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65040(transcript)|ensemblbacteria:TP_0039(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0039; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8xb0ZAjIxX2YZcGMDcGgvM/3qMo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:87735BCD3CE3698B|rigid:Of0WK8wH695jRsMqEbTpKQSVikU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83081 uniprotkb:O83398 intact:EBI-1592348|ensemblbacteria:AAC65040 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y039_trepa(display_long)|uniprotkb:TP_0039(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592353|imex:IM-9152-59 author score:0.384703151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65040(transcript)|ensemblbacteria:TP_0039(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0039; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8xb0ZAjIxX2YZcGMDcGgvM/3qMo243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:739A012DA21B4C9B|rigid:ASqCJ81wczPYqTXzQpKk3j2Z39c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83081 uniprotkb:O83282 intact:EBI-1592348|ensemblbacteria:AAC65040 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y039_trepa(display_long)|uniprotkb:TP_0039(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592371|imex:IM-9152-62 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65040(transcript)|ensemblbacteria:TP_0039(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0039; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8xb0ZAjIxX2YZcGMDcGgvM/3qMo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:4CA8BBD678820AA1|rigid:VzZOvR4XbO7m0y4GufI4OJk/SM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83581 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1592377|ensemblbacteria:AAC65544|ensemblbacteria:AGN75758 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83581_trepa(display_long)|uniprotkb:TP_0571(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592386|imex:IM-9152-64 author score:0.510472021 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR007156(LemA)|interpro:IPR023353|refseq:WP_010882018.1|ensemblbacteria:AAC65544(transcript)|ensemblbacteria:AGN75758(transcript)|ensemblbacteria:TP_0571(gene)|ensemblbacteria:TPANIC_0571(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0571; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:HfwjUq3UpllvOWP2yYf/+mNk5cA243276 intact-crc:192E0F4E99A0A308|rigid:c0PbQIi90O/lo6q9Cw+8voRDfdI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83581 uniprotkb:O83098 intact:EBI-1592377|ensemblbacteria:AAC65544|ensemblbacteria:AGN75758 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:o83581_trepa(display_long)|uniprotkb:TP_0571(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592380|imex:IM-9152-63 author score:0.671495353 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007156(LemA)|interpro:IPR023353|refseq:WP_010882018.1|ensemblbacteria:AAC65544(transcript)|ensemblbacteria:AGN75758(transcript)|ensemblbacteria:TP_0571(gene)|ensemblbacteria:TPANIC_0571(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0571; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HfwjUq3UpllvOWP2yYf/+mNk5cA243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:E2E752CBDA30E9EF|rigid:CB3ZW6Y6FDGktNTWzNgdGy0y8UU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83581 uniprotkb:O83413 intact:EBI-1592377|ensemblbacteria:AAC65544|ensemblbacteria:AGN75758 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83581_trepa(display_long)|uniprotkb:TP_0571(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592404|imex:IM-9152-67 author score:0.143215719 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007156(LemA)|interpro:IPR023353|refseq:WP_010882018.1|ensemblbacteria:AAC65544(transcript)|ensemblbacteria:AGN75758(transcript)|ensemblbacteria:TP_0571(gene)|ensemblbacteria:TPANIC_0571(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0571; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HfwjUq3UpllvOWP2yYf/+mNk5cA243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:4A0589EB13614F64|rigid:K8qVQh8tnSDUqPwmTSQXKGWW9m0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83581 uniprotkb:O83099 intact:EBI-1592377|ensemblbacteria:AAC65544|ensemblbacteria:AGN75758 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83581_trepa(display_long)|uniprotkb:TP_0571(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592398|imex:IM-9152-66 author score:0.305843263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007156(LemA)|interpro:IPR023353|refseq:WP_010882018.1|ensemblbacteria:AAC65544(transcript)|ensemblbacteria:AGN75758(transcript)|ensemblbacteria:TP_0571(gene)|ensemblbacteria:TPANIC_0571(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0571; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HfwjUq3UpllvOWP2yYf/+mNk5cA243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:F9BCCEE3913F006A|rigid:9qjRSJAbn3wOIxHSu+S/RqsiIbY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83581 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1592377|ensemblbacteria:AAC65544|ensemblbacteria:AGN75758 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83581_trepa(display_long)|uniprotkb:TP_0571(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592392|imex:IM-9152-65 author score:0.391095335 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR007156(LemA)|interpro:IPR023353|refseq:WP_010882018.1|ensemblbacteria:AAC65544(transcript)|ensemblbacteria:AGN75758(transcript)|ensemblbacteria:TP_0571(gene)|ensemblbacteria:TPANIC_0571(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0571; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:HfwjUq3UpllvOWP2yYf/+mNk5cA243276 intact-crc:CA9353B5C43DAB76|rigid:t/MJfFNZiBIhCGlYdc4W9McQe38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83225 uniprotkb:O83413 intact:EBI-1592414|ensemblbacteria:AAC65180 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:rs3_trepa(display_long)|uniprotkb:rpsC(gene name)|psi-mi:rpsC(display_short)|uniprotkb:TP_0195(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592420|imex:IM-9152-69 author score:0.159289405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005704(Ribosomal protein S3, bacterial)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR018280|ensemblbacteria:AAC65180(transcript)|ensemblbacteria:TP_0195(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881642.1|interpro:IPR036419 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0195; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4NxA1altsz72xeerBwtzWfYyGtQ243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:EB4A535166674238|rigid:8ZE6fJLvwKJwDjmSBDFGdsYMKwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83225 uniprotkb:O83570 intact:EBI-1592414|ensemblbacteria:AAC65180 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:rs3_trepa(display_long)|uniprotkb:rpsC(gene name)|psi-mi:rpsC(display_short)|uniprotkb:TP_0195(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592410|imex:IM-9152-68 author score:0.669439946 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005704(Ribosomal protein S3, bacterial)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR018280|ensemblbacteria:AAC65180(transcript)|ensemblbacteria:TP_0195(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881642.1|interpro:IPR036419 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0195; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4NxA1altsz72xeerBwtzWfYyGtQ243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:0BEE4AF1A9B1E18D|rigid:1z87qKHChm+31TJsJos/4EoxEN4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83225 uniprotkb:O83745 intact:EBI-1592414|ensemblbacteria:AAC65180 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:rs3_trepa(display_long)|uniprotkb:rpsC(gene name)|psi-mi:rpsC(display_short)|uniprotkb:TP_0195(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592426|imex:IM-9152-70 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005704(Ribosomal protein S3, bacterial)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR018280|ensemblbacteria:AAC65180(transcript)|ensemblbacteria:TP_0195(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881642.1|interpro:IPR036419 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0195; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4NxA1altsz72xeerBwtzWfYyGtQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:65FBD12794491C3D|rigid:w+KDbHGdbaCJwwctoGIXyDQ64W4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83300 uniprotkb:O83312 intact:EBI-1592432|ensemblbacteria:AAC65264|ensemblbacteria:AGN75487 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83300_trepa(display_long)|uniprotkb:TP_0276(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592441|imex:IM-9152-72 author score:0.353260356 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015947(PUA-like)|interpro:IPR006700(Protein of unknown function DUF558, methyltransferase predicted)|ensemblbacteria:AAC65264(transcript)|ensemblbacteria:AGN75487(transcript)|ensemblbacteria:TP_0276(gene)|ensemblbacteria:TPANIC_0276(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR029026|interpro:IPR029028|refseq:WP_010881725.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0276; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E8XJM8V4WrobzwXBWpPYZ5dYb9I243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:83447A16B90D77B3|rigid:WqXV2QaB9f3JXfKAYgqukou3t9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83300 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1592432|ensemblbacteria:AAC65264|ensemblbacteria:AGN75487 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83300_trepa(display_long)|uniprotkb:TP_0276(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592435|imex:IM-9152-71 author score:0.666276164 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR015947(PUA-like)|interpro:IPR006700(Protein of unknown function DUF558, methyltransferase predicted)|ensemblbacteria:AAC65264(transcript)|ensemblbacteria:AGN75487(transcript)|ensemblbacteria:TP_0276(gene)|ensemblbacteria:TPANIC_0276(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|interpro:IPR029026|interpro:IPR029028|refseq:WP_010881725.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0276; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:E8XJM8V4WrobzwXBWpPYZ5dYb9I243276 intact-crc:B93E59D7F3BA7F81|rigid:bWlYbF06/KoWHVCxUIqHQ1GAeZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83528 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1592459|ensemblbacteria:AAC65503|ensemblbacteria:AGN75704 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:o83528_trepa(display_long)|uniprotkb:TP_0515(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592462|imex:IM-9152-74 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 interpro:IPR007543(Organic solvent tolerance protein)|ensemblbacteria:AAC65503(transcript)|ensemblbacteria:AGN75704(transcript)|ensemblbacteria:TP_0515(gene)|ensemblbacteria:TPANIC_0515(gene)|go:"GO:0010033"(response to organic substance)|go:"GO:0019867"(outer membrane)|go:"GO:0061024"(membrane organization)|refseq:WP_010881964.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0515|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:kiyeDheuVMOrcXShaYr7g5+wu/c243276 intact-crc:1B4215E110C73E6E|rigid:fLP8hocJaWzbXOf2MPjqkVn3kHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83206 uniprotkb:O83636 intact:EBI-1592447|ensemblbacteria:AAC65166 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:y176_trepa(display_long)|uniprotkb:TP_0176(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592453|imex:IM-9152-73 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65166(transcript)|ensemblbacteria:TP_0176(gene) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0176|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LKjhLMTLYIdINoznqOhfwa55nFE243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:CA5DC0F14BE37962|rigid:3MUmGl0WlYkuhi7GYJqF53klVXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83428 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1198445|intact:EBI-1582090|ensemblbacteria:AAC65401|ensemblbacteria:AGN75608 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:o83428_trepa(display_long)|uniprotkb:TP_0413(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592484|imex:IM-9152-77 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|refseq:WP_010881861.1|ensemblbacteria:AAC65401(transcript)|ensemblbacteria:AGN75608(transcript)|ensemblbacteria:TP_0413(gene)|ensemblbacteria:TPANIC_0413(gene)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016868"(intramolecular transferase activity, phosphotransferases)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0413|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:xdf7iMFGW04XcnA65OQGOvw/VAE243276 intact-crc:A26A5CFD9B7B551A|rigid:RdycKdKl4eEbxAibg/ey1L2u1Ho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83336 uniprotkb:O83636 intact:EBI-1198975|intact:EBI-1585224|ensemblbacteria:AAC65305 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:y314_trepa(display_long)|uniprotkb:TP_0314(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592478|imex:IM-9152-76 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65305(transcript)|ensemblbacteria:TP_0314(gene) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0314|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rjZuIwOLYsidiK8cJHZrG52uw9o243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:0411FBF10D9D389D|rigid:98W4y3m0z70/JUDQ9VoSi1ifjGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O84001 uniprotkb:O83636 intact:EBI-1592468|ensemblbacteria:AAC26593 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:apt_trepa(display_long)|uniprotkb:apt(gene name)|psi-mi:apt(display_short)|uniprotkb:TP_1039(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592472|imex:IM-9152-75 author score:0.665858674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005764(Adenine phosphoribosyl transferase)|interpro:IPR000836(Phosphoribosyltransferase)|refseq:WP_010882483.1|ensemblbacteria:AAC26593(transcript)|ensemblbacteria:TP_1039(gene)|go:"GO:0003999"(adenine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0044209"(AMP salvage)|interpro:IPR029057 interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_1039|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0JCvhwQKBKS5ynaa0XMmjN7mg0I243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:B575D8142360B71C|rigid:VR8P5z0294zQge1zquj4tFs2u2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83717 uniprotkb:O83636 intact:EBI-1584293|ensemblbacteria:AAC65703|ensemblbacteria:AGN75909 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:o83717_trepa(display_long)|uniprotkb:TP_0735(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592496|imex:IM-9152-79 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017896|interpro:IPR006004("Glutamate synthase (NADPH), homotetrameric")|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR023753|ensemblbacteria:AAC65703(transcript)|ensemblbacteria:AGN75909(transcript)|ensemblbacteria:TP_0735(gene)|ensemblbacteria:TPANIC_0735(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010882180.1|interpro:IPR028261|interpro:IPR036188 interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0735|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G49VLaWESe0ywK6wQ33JQEyEMzg243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:6698F17ED507D9DC|rigid:I4OWxpdU/98mMhlNikNG0VjxmdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83683 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1586466|ensemblbacteria:AAC65653 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:y677_trepa(display_long)|uniprotkb:TP_0677(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592490|imex:IM-9152-78 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 ensemblbacteria:AAC65653(transcript)|ensemblbacteria:TP_0677(gene)|refseq:WP_010882122.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0677|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:UHLVvx30vXgRFAnf6IHOfk/TsAI243276 intact-crc:0180C9D202152BC0|rigid:c+J8zziRgiYe2ZdEMbIFJ2WTKFk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83636 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592508|imex:IM-9152-81 author score:0.590599372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:FDC40B7C12D45F95|rigid:alW81VBKXIofBMcrzK0Vgh26lJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83952 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1587505|ensemblbacteria:AAC65950 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:y987_trepa(display_long)|uniprotkb:TP_0987(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592502|imex:IM-9152-80 author score:0.659842166 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 ensemblbacteria:AAC65950(transcript)|ensemblbacteria:TP_0987(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0987|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:XPQPEHLaISB8DFhui/DyfCu12dQ243276 intact-crc:B2F39194C77F7C2F|rigid:7Y6cxLYwpbLz5boCGGzg/4yd/8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83636 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592514|imex:IM-9152-82 author score:0.21826134 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:7C727AA2B99128EF|rigid:6dP0HgfAGp6vAEzXC8D9s8EHUmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83745 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592520|imex:IM-9152-83 author score:0.046274348 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:5141747436A9D728|rigid:ozJUmY6nVjgCQ7bIqXw5ewV7DXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83282 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592526|imex:IM-9152-84 author score:0.019055643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:E2996D49A4D17BF0|rigid:G2G0TWvoKm3EOfdwsgQ3Wra3WsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83636 uniprotkb:O83954 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592532|imex:IM-9152-85 author score:0.015834394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:6BB1EEF933C34642|rigid:8ZbGV05kRZ7F8gd1JtzRZBVMKOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83636 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1592450|ensemblbacteria:AAC65600|ensemblbacteria:AGN75809 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83636_trepa(display_long)|uniprotkb:TP_0628(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592538|imex:IM-9152-86 author score:0.000951547 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR007229(Nicotinate phosphoribosyltransferase-related)|interpro:IPR006405(Nicotinate phosphoribosyltransferase putative)|interpro:IPR040727|ensemblbacteria:AAC65600(transcript)|ensemblbacteria:AGN75809(transcript)|ensemblbacteria:TP_0628(gene)|ensemblbacteria:TPANIC_0628(gene)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0004516"(nicotinate phosphoribosyltransferase activity)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882074.1|interpro:IPR041525|interpro:IPR041619|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0628; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:4BoHDJlvs3SdVzctzPX67qIH5wQ243276 intact-crc:D1D5DF9BE31747EB|rigid:jV/j4tCWMYTvIU0ds+q+KkhcTlI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83323 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1592544|ensemblbacteria:AAC65289|ensemblbacteria:AGN75505 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:rfuc_trepa(display_long)|uniprotkb:rfuC(gene name)|psi-mi:rfuC(display_short)|uniprotkb:TPANIC_0301(orf name)|uniprotkb:TP_0301(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592547|imex:IM-9152-87 author score:0.665852431 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001851(Bacterial inner-membrane translocator)|ensemblbacteria:AAC65289(transcript)|ensemblbacteria:AGN75505(transcript)|ensemblbacteria:TP_0301(gene)|ensemblbacteria:TPANIC_0301(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010881750.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0301; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:sJ3UuiarA2xBNVdqwKO/NDwKnNo243276 intact-crc:D334F5526A0A64F5|rigid:6LoqSTPwmf/UmwluvlCbC27vjiQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83323 uniprotkb:O83887 intact:EBI-1592544|ensemblbacteria:AAC65289|ensemblbacteria:AGN75505 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:rfuc_trepa(display_long)|uniprotkb:rfuC(gene name)|psi-mi:rfuC(display_short)|uniprotkb:TPANIC_0301(orf name)|uniprotkb:TP_0301(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592553|imex:IM-9152-88 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001851(Bacterial inner-membrane translocator)|ensemblbacteria:AAC65289(transcript)|ensemblbacteria:AGN75505(transcript)|ensemblbacteria:TP_0301(gene)|ensemblbacteria:TPANIC_0301(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010881750.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0301; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sJ3UuiarA2xBNVdqwKO/NDwKnNo243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:5B01BF6C1BCEE254|rigid:u5tufv6Uc1yXyx3cz8QBaMSS4VQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83261 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592565|imex:IM-9152-90 author score:0.635157622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:31B4451BAE63F778|rigid:1hthfWJJgCfrm38Nk6p7zq2NyBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83373 uniprotkb:O83843 intact:EBI-1582513|ensemblbacteria:AAC65341 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592559|imex:IM-9152-89 author score:0.665748919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 intact-crc:73AA2C1F0A3AC270|rigid:xuoILTiRzMqpDqc4nWgK6uxA+dg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83843 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592571|imex:IM-9152-91 author score:0.622591587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 intact-crc:626FFFA67057CB5F|rigid:y0BpaAgO0vMUlDdsxE+z5BTEgBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83843 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592577|imex:IM-9152-92 author score:0.544257149 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 intact-crc:4F62EA5E0D3DD77A|rigid:QuYBc2ftNtIQcEDBovtB1QM75RU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83312 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592595|imex:IM-9152-95 author score:0.237102582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:814FD746D9B7AF95|rigid:SqTfXqjYfpVNVZxthYcrcJLEtV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83805 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592583|imex:IM-9152-93 author score:0.497258971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:3717F599A0680B76|rigid:P63987MPedZfpmT+ms/XeBBkBCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:P21992 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592589|imex:IM-9152-94 author score:0.312982552 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:8626C591D647094D|rigid:w3imgcffcFIAuxjS3jpU5crjCqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83843 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592607|imex:IM-9152-97 author score:0.113339703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 intact-crc:9E74C93EFE79937A|rigid:DTEFtQMNWpE6tpLMH4HZSDYQoKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83099 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592601|imex:IM-9152-96 author score:0.232267228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:5D705018BCAEB6AF|rigid:t54P/l+IqcddOlOxUvxWPapfJmc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83282 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592613|imex:IM-9152-98 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:7DD7DD7F238BB8C1|rigid:R+Z5ZUZSH/pRT9zN/dNSak6ndJs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83843 uniprotkb:O83958 intact:EBI-1198862|intact:EBI-1588522|ensemblbacteria:AAC65847 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y873_trepa(display_long)|uniprotkb:TP_0873(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592619|imex:IM-9152-99 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882316.1|ensemblbacteria:AAC65847(transcript)|ensemblbacteria:TP_0873(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0873; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+e/MtR94aFPEq3AqI7np6LJO334243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9D93AD5FADE0E106|rigid:MaOO8QxuS8cfNeeFLprjA5TfZZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83962 uniprotkb:O83102 intact:EBI-1592165|ensemblbacteria:AAC26585 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592625|imex:IM-9152-100 author score:0.665748919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:05BC2D1C155FB13E|rigid:5RjkHojyaJQvGwbqrysGMEicczM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83102 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592635|imex:IM-9152-101 author score:0.549833253 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:AA40CD1DF590140C|rigid:3EkBgMlvybScWGTG75CeraghhIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83102 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592647|imex:IM-9152-103 author score:0.417259429 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:4E6C0A6B5B4CA8A4|rigid:BblHBatetgM39JtGjnPIFacGBh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83102 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592641|imex:IM-9152-102 author score:0.430427006 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:5C0D06CD8F2A1F01|rigid:Ro0mnlNFD5FumDd2YWxaOmJyYnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83102 uniprotkb:O83531 intact:EBI-1592629|ensemblbacteria:AAC65058 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592659|imex:IM-9152-105 author score:0.272857387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:8A36F5F1015649D9|rigid:P1VJ0+r0BqrBTA95EZ/2iJB1gwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83102 uniprotkb:O83398 intact:EBI-1592629|ensemblbacteria:AAC65058 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592653|imex:IM-9152-104 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:B1CA8DDA31F7C567|rigid:H/sapO3mbkwjmmvYvytutGrrg6o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83102 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592665|imex:IM-9152-106 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:78037C348F12CD9D|rigid:Nc8HIyTzGTWHwBppiVwkVoG+JEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83102 uniprotkb:O83767 intact:EBI-1592629|ensemblbacteria:AAC65058 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592671|imex:IM-9152-107 author score:0.066028043 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:3CB72AF679EF1618|rigid:tRpTkxj2oyCXJjLphW3iH8IHEzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83102 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592677|imex:IM-9152-108 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:C66D6212E6E6C778|rigid:X3D/AcXYfLEzHkejjH6sGX7Xf/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83102 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592689|imex:IM-9152-110 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:95671B57EA6328F2|rigid:ZJN8/pD+JWE2SktNyGFSz0OpHJU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83102 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1592629|ensemblbacteria:AAC65058 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:rs6_trepa(display_long)|uniprotkb:rpsF(gene name)|psi-mi:rpsF(display_short)|uniprotkb:TP_0063(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592683|imex:IM-9152-109 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR000529(Ribosomal protein S6)|interpro:IPR020814|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|ensemblbacteria:AAC65058(transcript)|ensemblbacteria:TP_0063(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881512.1|interpro:IPR035980 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0063; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:taxokUlg2435BeTTOWvpzUdnoBg243276 intact-crc:AFA25706075ACF6C|rigid:B9WxsofcRVTTZb1gV5RC+i4/4vU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83113 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592698|imex:IM-9152-111 author score:0.665652367 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:5B103E7FC78537AC|rigid:w+VpiB3lhKnDDP16Hia7kRAG/qM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16055 uniprotkb:O83113 intact:EBI-1581538|uniprotkb:O83201|ensemblbacteria:AAC65160 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:ta15_trepa(display_long)|uniprotkb:Major membrane immunogen(gene name synonym)|uniprotkb:TP_0171(locus name)|uniprotkb:tpp15(gene name)|psi-mi:tpp15(display_short) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592710|imex:IM-9152-113 author score:0.579667473 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007329(FMN-binding)|interpro:IPR017058(Major membrane immunogen, tpp15, predicted)|ensemblbacteria:AAC65160(transcript)|ensemblbacteria:TP_0171(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0171|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6fawJAEoGBKVKyVBIkwPY6wuHQ0243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:8906EB8BD701D480|rigid:LpGKO10dFyWx1sfbIDwaCXGlsY0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O66107 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592704|imex:IM-9152-112 author score:0.654425952 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:5B0F301ACA310D7E|rigid:InTvYguCRAs53wfzMH0sIF59umg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83113 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592722|imex:IM-9152-115 author score:0.575151361 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:B2B75CAA4F7D6FC8|rigid:etjxVsXq1S/h4leYDcq0hvdamvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83113 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592716|imex:IM-9152-114 author score:0.578406625 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:5B0516D1EA422033|rigid:KRus6k3+Bup7fx5pU6ZGZ2VXzMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O83305 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592734|imex:IM-9152-117 author score:0.280103578 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:45A7336457BCCF78|rigid:xo5+Yd9+5MPWP1R+RhtR21Bm7Z0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83113 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592728|imex:IM-9152-116 author score:0.539883493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:930F363CA1214B74|rigid:h1CddC4X1awi7OR/XQKcm8vIIkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O83745 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592752|imex:IM-9152-120 author score:0.04911944 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:AB6D1587065EAEB2|rigid:E3Kiq8Mr0Iips1weafxcU08PnCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O83413 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592746|imex:IM-9152-119 author score:0.091948564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6D230ABC60E81154|rigid:+SjcgvpT4P4yMFXgoEb5GWNjGoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O83982 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592740|imex:IM-9152-118 author score:0.274707055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:C80B7B1EB6F9F2FE|rigid:xU5SESMkJNqDWtGGHkv5BJkD8Rc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83113 uniprotkb:O83954 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592764|imex:IM-9152-122 author score:0.016840989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:7E033094DF155A31|rigid:kNyIO/E6wftCqwhEIohqYcjO3X4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83113 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592758|imex:IM-9152-121 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:695C000368EC6867|rigid:kEGTvU5wTHKEPNPGLGza4kY7Xoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83873 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592776|imex:IM-9152-124 author score:0.665120623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:7BC6F060DF17C572|rigid:tSk4/qdLtkEACZrC1FtYYC3uUqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83113 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1592695|ensemblbacteria:AAC65069|ensemblbacteria:AGN75293 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83113_trepa(display_long)|uniprotkb:TP_0074(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592770|imex:IM-9152-123 author score:0.001013011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|ensemblbacteria:AAC65069(transcript)|ensemblbacteria:AGN75293(transcript)|ensemblbacteria:TP_0074(gene)|ensemblbacteria:TPANIC_0074(gene)|refseq:WP_010881523.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0074; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:BJssXCG8CfqxVpYN79XnXbgEWX4243276 intact-crc:FB9B3A9521BD1539|rigid:VkI+OZirqqVIjDlAktjVE60ewyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83138 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1198745|intact:EBI-1582971|ensemblbacteria:AAC65095|ensemblbacteria:AGN75319 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:o83138_trepa(display_long)|uniprotkb:TP_0100(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592788|imex:IM-9152-1063 author score:0.595090448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR013740(Redoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|refseq:WP_010881549.1|ensemblbacteria:AAC65095(transcript)|ensemblbacteria:AGN75319(transcript)|ensemblbacteria:TP_0100(gene)|ensemblbacteria:TPANIC_0100(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036249 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0100|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:WRj9yJvMgdIyHzWbNWKfwP6aYKQ243276 intact-crc:238F209AEBA90C4A|rigid:MemxxVJ6oavNi6h+jPVIh6GZW3g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83411 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592782|imex:IM-9152-471 author score:0.63361933 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 intact-crc:F648B4625E24607E|rigid:b6XzrsxwciSiVZtS3pg0rByeJv4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83873 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592800|imex:IM-9152-1065 author score:0.455041183 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:E0F73248FCA07010|rigid:kX7MsnW0YdQX5mkPfgIhnKIVkCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83873 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592794|imex:IM-9152-1064 author score:0.562284136 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0064|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:BA62BC668CD0B868|rigid:20lE/N2XlNIVG9VjhiEsQIUS/Nw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83873 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592812|imex:IM-9152-1067 author score:0.315913318 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:42007C4846FABAB3|rigid:OqHjYIGa45lYWer+WNrFSvZMjQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83804 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592806|imex:IM-9152-1066 author score:0.370443541 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:8E40C2279B7C6016|rigid:I5+3rZxgyrUKK1vbITeYCzY1j5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:P21992 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592824|imex:IM-9152-1069 author score:0.214959941 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:8FF2711B23A0DD13|rigid:096hEgrwHAv7Kfz6zAIMItAhRwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83873 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592818|imex:IM-9152-1068 author score:0.293122498 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:469F17CF52DDC7D9|rigid:t21LCPbORA4CNRTTupkOl/MmDpw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83877 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592836|imex:IM-9152-1071 author score:0.183384552 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:ED43CB7B03834920|rigid:2fx0oe1UgADgvM0umaZ3HkZXuwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83873 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592830|imex:IM-9152-1070 author score:0.199121537 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:919DA789862DEB31|rigid:50g8DsES3rvDKDiZuwa5H1DQpQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83574 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592848|imex:IM-9152-1073 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:911B6139C26CFF36|rigid:n+GyZbeVeyTCxFuW84nELx9ANqQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83873 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592842|imex:IM-9152-1072 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:5C602C226696EF07|rigid:F3q7J1E5sJvab0ijqeFBCRUOil0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83667 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592860|imex:IM-9152-1075 author score:0.063917372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:2CB21AFE33824561|rigid:BORgwoUzsD2QbVNL+WwtNwJmGW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83873 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592854|imex:IM-9152-1074 author score:0.103450393 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:7B685E41774DD47C|rigid:fCEW5S7wmBwdc1G4AEqzMXeVPWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83873 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592872|imex:IM-9152-1077 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:B5257960DB07E451|rigid:h7mHgzmNwm3bj2CfdhHFX72Phtg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83873 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1587062|ensemblbacteria:AAC65856 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592866|imex:IM-9152-1076 author score:0.043607063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 intact-crc:2AE52A50EF9DD3CB|rigid:Or6/YiTIVwsuVGRTq5sE9tnI7TI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74931 uniprotkb:O83572 intact:EBI-1198709|intact:EBI-1592888|ensemblbacteria:AAC65683 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:fliq_trepa(display_long)|uniprotkb:fliQ(gene name)|psi-mi:fliQ(display_short)|uniprotkb:TP_0717(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592884|imex:IM-9152-1079 author score:0.664579627 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002191(Bacterial export protein FliQ, family 3)|interpro:IPR006305(Flagellar biosynthesis protein FliQ)|ensemblbacteria:AAC65683(transcript)|ensemblbacteria:TP_0717(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0717; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GAgnHPduZjnw1xL9YyxIug24C3E243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:3DE61DE854CC2877|rigid:l2AwfQ6EBpQxqhNRS8aVCJpsjYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83873 uniprotkb:O83958 intact:EBI-1587062|ensemblbacteria:AAC65856 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:murd_trepa(display_long)|uniprotkb:murD(gene name)|psi-mi:murD(display_short)|uniprotkb:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase(gene name synonym)|uniprotkb:D-glutamic acid-adding enzyme(gene name synonym)|uniprotkb:TP_0903(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592878|imex:IM-9152-1078 author score:0.0013363 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR005762(UDP-N-acetylmuramoylalanine-D-glutamate ligase)|ensemblbacteria:AAC65856(transcript)|ensemblbacteria:TP_0903(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008764"(UDP-N-acetylmuramoylalanine-D-glutamate ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882346.1|interpro:IPR036565|interpro:IPR036615 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0903; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciR0v5/sQnu+wwVkOy+tsVlVGG8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BEF6C6A43E7B2B4A|rigid:y18xB3jH1+Uhe7zkrupeOVfRW2A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83261 uniprotkb:O83698 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592900|imex:IM-9152-1081 author score:0.663675566 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 intact-crc:BE689B7A14D1BF0E|rigid:7MBGByBTqc0a91Zboh8bXQRqg7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:P74931 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1198709|intact:EBI-1592888|ensemblbacteria:AAC65683 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:fliq_trepa(display_long)|uniprotkb:fliQ(gene name)|psi-mi:fliQ(display_short)|uniprotkb:TP_0717(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592894|imex:IM-9152-1080 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR002191(Bacterial export protein FliQ, family 3)|interpro:IPR006305(Flagellar biosynthesis protein FliQ)|ensemblbacteria:AAC65683(transcript)|ensemblbacteria:TP_0717(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0717; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:GAgnHPduZjnw1xL9YyxIug24C3E243276 intact-crc:9F2366B4BD52B37A|rigid:DJOMCL5UilNP2hgJu2dDwdws03g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83698 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592912|imex:IM-9152-1083 author score:0.255356726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 intact-crc:D55B33E6C6731FC2|rigid:XnJese8rKQqxSwLJFnC3mUKRj28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83698 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592906|imex:IM-9152-1082 author score:0.333292903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 intact-crc:D6C445FD15AD547B|rigid:GpBjz40Bai5HMSEL33/CJeeOrAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83698 uniprotkb:O83877 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592924|imex:IM-9152-1085 author score:0.126555569 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:3F3FD0321EA6BE48|rigid:J99ps1S7w2C2mP5zq26SZZTFfto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83698 uniprotkb:O83574 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592918|imex:IM-9152-1084 author score:0.186323126 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:59F6B8A8EB1D2F90|rigid:0WvbJbvJ6jRG0FyooVB54Nq/2Ho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83698 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592936|imex:IM-9152-1087 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 intact-crc:2E0292370E36990E|rigid:vTebTroJUnIxhgCvkbPexE2fcgM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83698 uniprotkb:O83767 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592930|imex:IM-9152-1086 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:2CE0B397307C96FD|rigid:gY0fLtI4NqSMtkvQ0Sngbhd4oS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83698 uniprotkb:O83954 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592942|imex:IM-9152-1088 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:7D7607C8317A4AF0|rigid:jeEeji2sNB6Kv6Iw0w7boSqo1X8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83311 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592954|imex:IM-9152-1090 author score:0.663675566 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:FD48C2FC107582E0|rigid:675r/izhwjntWfKnqZbFDh9edg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83698 uniprotkb:O83958 intact:EBI-1198761|intact:EBI-1585869|ensemblbacteria:AAC65669 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y700_trepa(display_long)|uniprotkb:TP_0700(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592948|imex:IM-9152-1089 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882145.1|ensemblbacteria:AAC65669(transcript)|ensemblbacteria:TP_0700(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0700; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aPqFmXDBq1hvERO6FRVzuJMZ7ew243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:C758011C3108CD1E|rigid:5F87dravz3zUGf8xF6FUrUv1PUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83311 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592966|imex:IM-9152-1092 author score:0.429670838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:EB902738286B22F2|rigid:D9/EupYGKBFbzGIReZyZ6jm1fNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83970 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592960|imex:IM-9152-1091 author score:0.461357314 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:ABAF609183148E2A|rigid:Oscr7GaWOcdAHFcxh3/K54e82Is false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83877 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592978|imex:IM-9152-1094 author score:0.126555569 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:4030DD6C16CBC67D|rigid:CQrai45+tKyC/tjoQ0sX2APOYUQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83982 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592972|imex:IM-9152-1093 author score:0.327337582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:E7B110CE219B685C|rigid:iYlk6fNXZ5BDjox4gIGT69GEREo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83311 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592990|imex:IM-9152-1096 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:53EFBEC93811EEC8|rigid:IN0mDzDC7JQq6oH69zBQfr+G5Lo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83311 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592984|imex:IM-9152-1095 author score:0.115122451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:D1117BBC8B8B60B9|rigid:CPU0IgA2lu4eUIapE5Tj+ygy9Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83392 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593008|imex:IM-9152-1099 author score:0.66345533 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0377; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:084D7833559158C8|rigid:NkPFLY1GIpmjTUm2m3aV9lf9Y0E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83311 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593002|imex:IM-9152-1098 author score:0.001301161 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:B8570C423965B52B|rigid:HfEJezZHf23M4UBIlPdQXasVrTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83282 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1592996|imex:IM-9152-1097 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0287; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9768E43DC9CE2F57|rigid:forCidnVv+LAQxveaDSSQx6Qx00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83392 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593014|imex:IM-9152-1100 author score:0.521595597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0377; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:65A3E705C42B38AB|rigid:IoNLosES53+nnrYGGX8Poi6JrwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83710 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1198680|intact:EBI-1593026|uniprotkb:Q56337|ensemblbacteria:AAC65681 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:flhb_trepa(display_long)|uniprotkb:flhB(gene name)|psi-mi:flhB(display_short)|uniprotkb:TP_0715(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593036|imex:IM-9152-1103 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR006136(Flagellar biosynthetic protein FlhB)|interpro:IPR006135(Type III secretion exporter)|interpro:IPR029025|refseq:WP_010882160.1|ensemblbacteria:AAC65681(transcript)|ensemblbacteria:TP_0715(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0715; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:5ZTxbvKPj8yzBccfblZByWaphdM243276 intact-crc:0BDCFBB9953711DB|rigid:yeWAOc/DKJ/jLBPsNaH+XXr4h/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83710 uniprotkb:O83572 intact:EBI-1198680|intact:EBI-1593026|uniprotkb:Q56337|ensemblbacteria:AAC65681 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:flhb_trepa(display_long)|uniprotkb:flhB(gene name)|psi-mi:flhB(display_short)|uniprotkb:TP_0715(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593030|imex:IM-9152-1102 author score:0.662878829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006136(Flagellar biosynthetic protein FlhB)|interpro:IPR006135(Type III secretion exporter)|interpro:IPR029025|refseq:WP_010882160.1|ensemblbacteria:AAC65681(transcript)|ensemblbacteria:TP_0715(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0715; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5ZTxbvKPj8yzBccfblZByWaphdM243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:FE2E241805D1CDA0|rigid:7xvPBqu2eqYdjlMMDUbY6lOHSe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83392 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198676|intact:EBI-1586503|ensemblbacteria:AAC65363 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83392_trepa(display_long)|uniprotkb:TP_0377(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593020|imex:IM-9152-1101 author score:0.333073726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 ensemblbacteria:AAC65363(transcript)|ensemblbacteria:TP_0377(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0377; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:E8NQgFjR8Dik+G5aUCn++vQljek243276 intact-crc:A1E2B57AA1267BC3|rigid:G+9qHQ9vW0zwiNm5Gs78guIMuaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83630 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593048|imex:IM-9152-1105 author score:0.643510429 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 intact-crc:ADFFABA6B1F63A84|rigid:33rsqkqLY7uRj4QkWXmUilmM0mU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83666 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593042|imex:IM-9152-1104 author score:0.661816723 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0660|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:2317B5B7808CE49F|rigid:7i6hk9S+P1dj/1l/qL6IrWTQV3Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O83630 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593060|imex:IM-9152-1107 author score:0.612069792 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 intact-crc:CCFF72C9B945CF7D|rigid:XXyeRewS8Hr3pZ4Mf3pRpsaga88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83647 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593054|imex:IM-9152-1106 author score:0.631064977 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:AAF7497D97C2AA80|rigid:9WfFqjHmrj4ckS9pvQdLxRx36io false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83532 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593078|imex:IM-9152-1110 author score:0.492854561 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:74D475D2DE8590B8|rigid:SXvVTiJP/s2m/w/r3rDeXfk/lqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:Q08255 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593072|imex:IM-9152-1109 author score:0.592727782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:63A250B2E9C92951|rigid:KbDmHeiVEsBjBozhZdFMLI3W1kk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83630 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593066|imex:IM-9152-1108 author score:0.605658352 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 intact-crc:F5B22560FC4D5BC0|rigid:V+8HvaQuDDgsYuTey0B4xrBqnOM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83463 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593090|imex:IM-9152-1112 author score:0.355727749 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:E32AAC65707B59AD|rigid:4UXvgq7TdWpWLI1zhIkIijc/YTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83709 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593084|imex:IM-9152-1111 author score:0.387141619 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:F1DFC36A4016F10A|rigid:grFhe/wU7FgsGHkAVt2YE7/ynNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83531 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593102|imex:IM-9152-1114 author score:0.248714004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:07345B266060F603|rigid:iFJxW4LlSaaQtje0EuH+W3/UkDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83305 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593096|imex:IM-9152-1113 author score:0.280103578 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:1DFB66CFCFAF68F1|rigid:LB91L3dxecQyZq1B5qQtBLOd/0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83630 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593114|imex:IM-9152-1116 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 intact-crc:1408F85852611CEF|rigid:sXnFrYRe1fXj5Ak9vC/f2xKEmPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83630 uniprotkb:O83413 intact:EBI-1590058|ensemblbacteria:AAC65603|ensemblbacteria:AGN75803 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83630_trepa(display_long)|uniprotkb:TP_0622(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593108|imex:IM-9152-1115 author score:0.091948564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65603(transcript)|ensemblbacteria:AGN75803(transcript)|ensemblbacteria:TP_0622(gene)|ensemblbacteria:TPANIC_0622(gene)|refseq:WP_010882068.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0622; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bBbWGGkdfaUjE0LdfzrBVUb6A4A243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:89913F2D1184A848|rigid:vIQclh5fRn/XIo0lEUYQbnN/KyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83644 uniprotkb:P21992 intact:EBI-1593124|ensemblbacteria:AAC65611 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:miaa_trepa(display_long)|uniprotkb:miaA(gene name)|psi-mi:miaA(display_short)|uniprotkb:"Isopentenyl-diphosphate:tRNA isopentenyltransferase"(gene name synonym)|uniprotkb:TP_0637(locus name)|uniprotkb:"Dimethylallyl diphosphate:tRNA dimethylallyltransferase"(gene name synonym) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593136|imex:IM-9152-1119 author score:0.313481504 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039657|interpro:IPR018022|ensemblbacteria:AAC65611(transcript)|ensemblbacteria:TP_0637(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0052381"(tRNA dimethylallyltransferase activity)|refseq:WP_010882082.1|interpro:IPR027417 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0637; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v1ibHSRp58mEjH75Dpo/qewyui0243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:9BE12209579AEBF1|rigid:URto+V4wnjtmQKdC1yhz24581Mc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83644 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1593124|ensemblbacteria:AAC65611 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:miaa_trepa(display_long)|uniprotkb:miaA(gene name)|psi-mi:miaA(display_short)|uniprotkb:"Isopentenyl-diphosphate:tRNA isopentenyltransferase"(gene name synonym)|uniprotkb:TP_0637(locus name)|uniprotkb:"Dimethylallyl diphosphate:tRNA dimethylallyltransferase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593130|imex:IM-9152-1118 author score:0.395660102 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR039657|interpro:IPR018022|ensemblbacteria:AAC65611(transcript)|ensemblbacteria:TP_0637(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0052381"(tRNA dimethylallyltransferase activity)|refseq:WP_010882082.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0637; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:v1ibHSRp58mEjH75Dpo/qewyui0243276 intact-crc:A4D67CAAD90924B9|rigid:GZJjAVx2RNKAqTliVB4PQCf9wfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83644 uniprotkb:O83412 intact:EBI-1593124|ensemblbacteria:AAC65611 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:miaa_trepa(display_long)|uniprotkb:miaA(gene name)|psi-mi:miaA(display_short)|uniprotkb:"Isopentenyl-diphosphate:tRNA isopentenyltransferase"(gene name synonym)|uniprotkb:TP_0637(locus name)|uniprotkb:"Dimethylallyl diphosphate:tRNA dimethylallyltransferase"(gene name synonym) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593120|imex:IM-9152-1117 author score:0.661485447 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039657|interpro:IPR018022|ensemblbacteria:AAC65611(transcript)|ensemblbacteria:TP_0637(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0052381"(tRNA dimethylallyltransferase activity)|refseq:WP_010882082.1|interpro:IPR027417 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0637; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:v1ibHSRp58mEjH75Dpo/qewyui0243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:6F8D1B2D8C8496B7|rigid:kQbfx7Wo/QbDNy8FejWSbmKY68M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O66075 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593148|imex:IM-9152-1121 author score:0.659731445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:F965747B94035BF8|rigid:UlmMpdSQi1NZGh3aLmvi/kMwHn4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83644 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1593124|ensemblbacteria:AAC65611 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:miaa_trepa(display_long)|uniprotkb:miaA(gene name)|psi-mi:miaA(display_short)|uniprotkb:"Isopentenyl-diphosphate:tRNA isopentenyltransferase"(gene name synonym)|uniprotkb:TP_0637(locus name)|uniprotkb:"Dimethylallyl diphosphate:tRNA dimethylallyltransferase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593142|imex:IM-9152-1120 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR039657|interpro:IPR018022|ensemblbacteria:AAC65611(transcript)|ensemblbacteria:TP_0637(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008033"(tRNA processing)|go:"GO:0052381"(tRNA dimethylallyltransferase activity)|refseq:WP_010882082.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0637; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:v1ibHSRp58mEjH75Dpo/qewyui0243276 intact-crc:84361D2FD0FEA462|rigid:1h2C8meJrlSQvLa5Gw6gsQ6fypU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66075 uniprotkb:O83670 intact:EBI-1593152|ensemblbacteria:AAC65244 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593164|imex:IM-9152-1123 author score:0.497258971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:7D0062E1F798E3F1|rigid:qulHWwmgC34kOcbCu91xkcdftWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66075 uniprotkb:O83738 intact:EBI-1593152|ensemblbacteria:AAC65244 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593158|imex:IM-9152-1122 author score:0.643488685 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:23C0594DAF162BFE|rigid:2/um/PWIXmJMMfEDceVRN79pyes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O66075 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593170|imex:IM-9152-1124 author score:0.417259429 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:86651BED0261EBDD|rigid:/akVyVHyVFQCV1EiyT79XAMdXt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O66075 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593176|imex:IM-9152-1125 author score:0.364917483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:6FCC0D1E1486CA55|rigid:2+B8ro8A8AYSygMHhJ27Z+5M5dI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O66075 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593182|imex:IM-9152-1126 author score:0.328192262 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:0EBCAD1E1C7306F5|rigid:XUjRTbu1VIlB1KwHz8H5X8uQk/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O66075 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593194|imex:IM-9152-1128 author score:0.210850521 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:2A54F4D297E61C5A|rigid:B4bDXcS5f85XDiINcZHvWsHX9bM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O66075 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593188|imex:IM-9152-1127 author score:0.306052744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:AAF28C50FBA0D13A|rigid:YcuBldkemt/1Q1aMsXNESqXOHq4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O66075 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593206|imex:IM-9152-1130 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:B00A6DB2D63F8EE4|rigid:bC3fnkgQmfP/bdCJh/kPbSzwo2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O66075 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593200|imex:IM-9152-1129 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:2CD804DBBFE39778|rigid:+v48BmeN9sZqT+9EETIRsPiriAs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O66075 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593212|imex:IM-9152-1131 author score:0.055314123 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0255; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:5A3EEC7685A7CFC7|rigid:CHFmsVIF61d1IPBs6fpPhnj5mOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83299 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593218|imex:IM-9152-1132 author score:0.657528895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 intact-crc:436C580B750EC3E4|rigid:NbXR3rp/sMEs+0ckIQOtQxCY4Bs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83299 uniprotkb:O83459 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593233|imex:IM-9152-1134 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:0BCBF1A3E08CA5EF|rigid:J7AckGZkddu/VYr8zMsyYMXPSMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83299 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593227|imex:IM-9152-1133 author score:0.645303091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 intact-crc:BD9192E4E8E35725|rigid:nnrBxucewwjS0OvjkfCGmkaFwz4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83299 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593251|imex:IM-9152-1137 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 intact-crc:C28850915BC9DBE7|rigid:sP/zqRGwYGl9m0L61fVnCr/UwEY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83299 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593245|imex:IM-9152-1136 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 intact-crc:791DBAED38EB1B03|rigid:7W1tk9rGsCKegoLkZi8ft9oRUwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83299 uniprotkb:O83305 intact:EBI-1593222|ensemblbacteria:AAC65263|ensemblbacteria:AGN75486 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83299_trepa(display_long)|uniprotkb:TP_0275(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593239|imex:IM-9152-1135 author score:0.376280693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004629(Glycosyl transferase WecB/TagA/CpsF)|ensemblbacteria:AAC65263(transcript)|ensemblbacteria:AGN75486(transcript)|ensemblbacteria:TP_0275(gene)|ensemblbacteria:TPANIC_0275(gene)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016740"(transferase activity)|refseq:WP_010881724.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0275; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yPLLfOoOOK1ioLLsZjGRxGV+2rc243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:5881D1F32A10DC25|rigid:X0+9FN7thYmNLqD43InTVle748Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O83634 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593260|imex:IM-9152-1138 author score:0.655653705 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:46FCCB5DCC0B823B|rigid:JgDNIzzayAPdUK3B3cU82aT1/Fs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O66107 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593266|imex:IM-9152-1139 author score:0.599091869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:9C3ED533955CDFFA|rigid:GmIPtPTEh5qaoAxg11W0AXFFNA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O83463 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593272|imex:IM-9152-1140 author score:0.399873643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:712682591202D545|rigid:vNoEQ+tc1i/V3iACpyyf6vpNrJ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O83305 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593278|imex:IM-9152-1141 author score:0.319518858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:96C639F5633EB8EC|rigid:TYdKsKVLDDMFb9IkQPfBAgblN/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83340 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1593257|ensemblbacteria:AAC65308 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593284|imex:IM-9152-1142 author score:0.285463752 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 intact-crc:32680DA80C700A24|rigid:zb9rb1rDb2fauAT+J+ehy5nPcfI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:P21992 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593290|imex:IM-9152-1143 author score:0.23869982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:F5298F41AA99BEDE|rigid:/pyhCHTpK4vux8COdCV4YctoQHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83340 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1593257|ensemblbacteria:AAC65308 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593302|imex:IM-9152-1145 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 intact-crc:CF2CEB37AD2D53F6|rigid:NNmtZc8CqWP8zkfymyREStHCyWw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83340 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1593257|ensemblbacteria:AAC65308 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593296|imex:IM-9152-1144 author score:0.215103369 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 intact-crc:8879754A48ECF200|rigid:y3iRuyR5Tnwfec3JdECToGFYGBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O83877 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593308|imex:IM-9152-1146 author score:0.119790274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:1E8BC83DB2CDA542|rigid:V0A41/xYt9Ysec0tZeZ0vrIUcYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83387 uniprotkb:O83970 intact:EBI-1593320|ensemblbacteria:AAC65357 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:rl25_trepa(display_long)|uniprotkb:rplY(gene name)|psi-mi:rplY(display_short)|uniprotkb:ctc(gene name synonym)|uniprotkb:General stress protein CTC(gene name synonym)|uniprotkb:TP_0372(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593324|imex:IM-9152-1148 author score:0.654025661 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR020057|interpro:IPR001021(Ribosomal protein L25)|interpro:IPR029751|ensemblbacteria:AAC65357(transcript)|ensemblbacteria:TP_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|refseq:WP_010881820.1|interpro:IPR037121 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0372; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWHfYOT+BPJjTV8IjOEQufMUDas243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:71BEA25E48C708E5|rigid:b9LVdMxi6yQFKo2mLcNztNxjGGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83340 uniprotkb:O83954 intact:EBI-1593257|ensemblbacteria:AAC65308 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y320_trepa(display_long)|uniprotkb:TP_0320(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593314|imex:IM-9152-1147 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65308(transcript)|ensemblbacteria:TP_0320(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0320; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7ad8eSdoexJu1DEOXYgY8NQAsJ8243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:3A7AC6D42C7016FC|rigid:q0GUj13I/UHniK+CJxk7AMi80Ec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83387 uniprotkb:O83927 intact:EBI-1593320|ensemblbacteria:AAC65357 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rl25_trepa(display_long)|uniprotkb:rplY(gene name)|psi-mi:rplY(display_short)|uniprotkb:ctc(gene name synonym)|uniprotkb:General stress protein CTC(gene name synonym)|uniprotkb:TP_0372(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593330|imex:IM-9152-1149 author score:0.416942463 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR020057|interpro:IPR001021(Ribosomal protein L25)|interpro:IPR029751|ensemblbacteria:AAC65357(transcript)|ensemblbacteria:TP_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|refseq:WP_010881820.1|interpro:IPR037121 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0372; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWHfYOT+BPJjTV8IjOEQufMUDas243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:258AF5EE68F148E6|rigid:5UneXgXCHtHrK8sArSivL3cnPko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83387 uniprotkb:O83877 intact:EBI-1593320|ensemblbacteria:AAC65357 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:rl25_trepa(display_long)|uniprotkb:rplY(gene name)|psi-mi:rplY(display_short)|uniprotkb:ctc(gene name synonym)|uniprotkb:General stress protein CTC(gene name synonym)|uniprotkb:TP_0372(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593336|imex:IM-9152-1150 author score:0.265754359 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR020057|interpro:IPR001021(Ribosomal protein L25)|interpro:IPR029751|ensemblbacteria:AAC65357(transcript)|ensemblbacteria:TP_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|refseq:WP_010881820.1|interpro:IPR037121 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0372; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWHfYOT+BPJjTV8IjOEQufMUDas243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:A15F9A5970233846|rigid:UrQ25XlP9ucnbLtgsxl5GYvKAgM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83387 uniprotkb:O83282 intact:EBI-1593320|ensemblbacteria:AAC65357 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rl25_trepa(display_long)|uniprotkb:rplY(gene name)|psi-mi:rplY(display_short)|uniprotkb:ctc(gene name synonym)|uniprotkb:General stress protein CTC(gene name synonym)|uniprotkb:TP_0372(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593342|imex:IM-9152-1151 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR020057|interpro:IPR001021(Ribosomal protein L25)|interpro:IPR029751|ensemblbacteria:AAC65357(transcript)|ensemblbacteria:TP_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|refseq:WP_010881820.1|interpro:IPR037121 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0372; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWHfYOT+BPJjTV8IjOEQufMUDas243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:AA202471E5540A98|rigid:pmp5MJ+qPm6grFhjcekZWdsk+QU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83387 uniprotkb:O83958 intact:EBI-1593320|ensemblbacteria:AAC65357 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rl25_trepa(display_long)|uniprotkb:rplY(gene name)|psi-mi:rplY(display_short)|uniprotkb:ctc(gene name synonym)|uniprotkb:General stress protein CTC(gene name synonym)|uniprotkb:TP_0372(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593348|imex:IM-9152-1152 author score:0.00218498 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR020057|interpro:IPR001021(Ribosomal protein L25)|interpro:IPR029751|ensemblbacteria:AAC65357(transcript)|ensemblbacteria:TP_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|refseq:WP_010881820.1|interpro:IPR037121 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0372; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWHfYOT+BPJjTV8IjOEQufMUDas243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:FA3FCD51EDA4F4CD|rigid:CTiIFSHjSL7A9X57sYeGqKHKPVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83137 uniprotkb:P45685 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593354|imex:IM-9152-1153 author score:0.653773655 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0099|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:C2D3BF998A8C6530|rigid:jE1BFfGeTJM0e0UMptxjiBGy1NQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:P45685 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593370|imex:IM-9152-1155 author score:0.590599372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:2ABC22233A11C7B7|rigid:vSuPkJ9G50MSQzlvnmVN1dHbgmE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27771 uniprotkb:P45685 intact:EBI-1593360|uniprotkb:O83775|ensemblbacteria:AAC65760 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:p5cr_trepa(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:TP_0797(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593364|imex:IM-9152-1154 author score:0.641486887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|ensemblbacteria:AAC65760(transcript)|ensemblbacteria:TP_0797(gene)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010882242.1|interpro:IPR029036|interpro:IPR036291 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0797|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nzwapTm7KjLpf0btHIa+PzwyOK4243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:56172A3C82F6907B|rigid:NJ2hdHuVcIHmZceYDVmB5/TGPMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:P45685 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593382|imex:IM-9152-1157 author score:0.55883503 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:9FC902FB01DE6590|rigid:5dEWFZdBBjPXH7/iKWHLP+YJ7L8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:P45685 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593376|imex:IM-9152-1156 author score:0.567810405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:DE2DE659F0CC9DA8|rigid:tIZOrTYMlxbfMTYbMicSciqdSyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O66107 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593394|imex:IM-9152-1159 author score:0.537694317 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:8B7338E8F3AB473A|rigid:AzDsq7zTykDgh8aRLSWr+J378Zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:P45685 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593388|imex:IM-9152-1158 author score:0.551048718 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:CAC75B22F0C3573F|rigid:aQXFwezMjrxvUgt8O5nVomt7u2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83982 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593406|imex:IM-9152-1161 author score:0.26240127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:32E57362D4C31F39|rigid:q9kOFWi2qd00CwM8CStn+FI5HMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83311 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593400|imex:IM-9152-1160 author score:0.497382283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:7DFD8737381D1204|rigid:fje6etmCjPEbezOsybjY7h1200U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83877 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593412|imex:IM-9152-1162 author score:0.095778469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:9C050DCDE7464402|rigid:xIQKBn8Wp3xMGTp/quWWtehh10s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83413 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593418|imex:IM-9152-1163 author score:0.086849309 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CC1D16634E8CD48D|rigid:UhuK3fMqlqVCG4SdbA58wrMLY8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:P45685 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593424|imex:IM-9152-1164 author score:0.055339904 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:D12FC5C56E5D58FD|rigid:MEFgN2WuoBcLCTjOpt4X9XHBBhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P45685 uniprotkb:O83954 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593430|imex:IM-9152-1165 author score:0.015834394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F26906F46FA5E063|rigid:dzbzpuDlm4HmV0lJcTQlQiQWnKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P45685 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593436|imex:IM-9152-1166 author score:0.000951547 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0046; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:D30E80D6F3B252B5|rigid:+lOeMeRzrzLGjUSJ4jEBx+6mgQE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83592 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1586275|ensemblbacteria:AAC65561 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593448|imex:IM-9152-1168 author score:0.607760467 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 intact-crc:527E0E1216EE4626|rigid:pLghEsAY3P/PKy+Axua/FxCEImk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83723 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593442|imex:IM-9152-1167 author score:0.651664885 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:40D78D254F9628BD|rigid:Mqm5NrsRmPCCTwjPRP1iayeQbBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83412 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593460|imex:IM-9152-1170 author score:0.542071132 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:1EBDC043F3AE1539|rigid:sZPaan6pSYofGsoJuJJajIUBrps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83596 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593454|imex:IM-9152-1169 author score:0.555403642 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:9C8E4CCA0472C8AB|rigid:hznsPau3DdEp2ad7vaUJrui7gYs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83592 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1586275|ensemblbacteria:AAC65561 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593466|imex:IM-9152-1171 author score:0.508516923 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 intact-crc:3C5B8A3E6A47696A|rigid:TYY17v4ZRPg7d7OY5R7VlNcblnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83752 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593472|imex:IM-9152-1172 author score:0.508516923 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:181BAE02D2F8E4F6|rigid:gDNGJ85+/I4OYCq8QG1f+fq3pjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83670 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593478|imex:IM-9152-1173 author score:0.481603579 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:C55B446F249C089B|rigid:XyrQaT+/PUL3ztLKpwrfN8Zs6bE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83738 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593484|imex:IM-9152-1174 author score:0.468177107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:DACCF14CFD05B6E3|rigid:99VMbmtRIDVRs8eNOmXCDJooe5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83305 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593490|imex:IM-9152-1175 author score:0.292909869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:E016E322D14B9B0E|rigid:tTtmiOZwoR6gJfhStSaSAhQcIQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83592 uniprotkb:O83398 intact:EBI-1586275|ensemblbacteria:AAC65561 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593496|imex:IM-9152-1176 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:4B596B35F3F218F9|rigid:MmWZIaWIKfLZGvtNVnBV9dOBlxY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83592 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1586275|ensemblbacteria:AAC65561 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593502|imex:IM-9152-1177 author score:0.216678193 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 intact-crc:B94FAD70AD6AC288|rigid:2xe3wYrQp9mDrHsiz93Kcci20/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83592 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1586275|ensemblbacteria:AAC65561 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y583_trepa(display_long)|uniprotkb:TP_0583(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593508|imex:IM-9152-1523 author score:0.090447395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65561(transcript)|ensemblbacteria:TP_0583(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0583; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:H/65Du+PCZrIcZ5iRrOK6uwsL48243276 intact-crc:52651C2999F6BFD3|rigid:dXtsQd/DiI6YoJEBkSDNwzYUSfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83253 uniprotkb:O83311 intact:EBI-1593518|ensemblbacteria:AAC65218 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:y224_trepa(display_long)|uniprotkb:TP_0224(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593514|imex:IM-9152-1524 author score:0.649325558 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65218(transcript)|ensemblbacteria:TP_0224(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0224; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YcgwZUUAzqQG2GtOr7R77YNOjL0243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:4704628F99C4D39E|rigid:W0quT/n50s8n2RzlLZEX203n7Ys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83253 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1593518|ensemblbacteria:AAC65218 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y224_trepa(display_long)|uniprotkb:TP_0224(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593523|imex:IM-9152-1525 author score:0.406113471 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65218(transcript)|ensemblbacteria:TP_0224(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0224; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:YcgwZUUAzqQG2GtOr7R77YNOjL0243276 intact-crc:0FFD7199A1D7652A|rigid:7ugdFNJFPPiQX/RjL67dYiN8Lbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83253 uniprotkb:O83312 intact:EBI-1593518|ensemblbacteria:AAC65218 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y224_trepa(display_long)|uniprotkb:TP_0224(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593529|imex:IM-9152-1526 author score:0.325184226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65218(transcript)|ensemblbacteria:TP_0224(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0224; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YcgwZUUAzqQG2GtOr7R77YNOjL0243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:C95F6C5628EBEE33|rigid:FukH7/rXwvRGGMFWwH9Mlx3jBpQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83291 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1593545|ensemblbacteria:AAC65255|ensemblbacteria:AGN75478 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83291_trepa(display_long)|uniprotkb:TP_0267(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593541|imex:IM-9152-1528 author score:0.649213234 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR007607(Protein of unknown function DUF583)|ensemblbacteria:AGN75478(transcript)|ensemblbacteria:TP_0267(gene)|ensemblbacteria:TPANIC_0267(gene)|ensemblbacteria:AAC65255(transcript)|refseq:WP_010881716.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0267; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:Ej+irE9Ibs/7sx5toT9RBAWR614243276 intact-crc:83D8519D252D3D8E|rigid:3IDJ8TzzI5veKwmTymf1pyecQzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83253 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1593518|ensemblbacteria:AAC65218 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y224_trepa(display_long)|uniprotkb:TP_0224(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593535|imex:IM-9152-1527 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65218(transcript)|ensemblbacteria:TP_0224(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0224; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:YcgwZUUAzqQG2GtOr7R77YNOjL0243276 intact-crc:32DBD0D0B735F9A3|rigid:8YT1goUiEA6SsCxZuJ8PKCQt6VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83850 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1586209|ensemblbacteria:AAC65842|ensemblbacteria:AGN76049 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83850_trepa(display_long)|uniprotkb:TP_0880(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593550|imex:IM-9152-1529 author score:0.649213234 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) ensemblbacteria:AAC65842(transcript)|ensemblbacteria:AGN76049(transcript)|ensemblbacteria:TP_0880(gene)|ensemblbacteria:TPANIC_0880(gene)|refseq:WP_010882323.1|interpro:IPR025699 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0880; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:YnCITab2vyISVmGkTw61JqUnMfk243276 intact-crc:393C699A86523B1D|rigid:KLXMagrptMktVSg2BIYYEurc23E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83903 uniprotkb:O83805 intact:EBI-1593556|ensemblbacteria:AAC65885 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:mure_trepa(display_long)|uniprotkb:murE(gene name)|psi-mi:murE(display_short)|uniprotkb:UDP-MurNAc-tripeptide synthetase(gene name synonym)|uniprotkb:TP_0933(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593560|imex:IM-9152-1530 author score:0.649213234 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005761(UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase)|ensemblbacteria:AAC65885(transcript)|ensemblbacteria:TP_0933(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882376.1|interpro:IPR035911|interpro:IPR036565|interpro:IPR036615 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0933; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ajV0qs/oSzFNPCE0HjQ5LujQOGE243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:C3BF776437C16AA4|rigid:P6vDY8Ns4n4QP/3Kcp1hJmEubqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83764 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1593570|ensemblbacteria:AAC65749|ensemblbacteria:AGN75957 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83764_trepa(display_long)|uniprotkb:TP_0785(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593566|imex:IM-9152-1531 author score:0.647316935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR005653(OstA-like protein)|ensemblbacteria:AAC65749(transcript)|ensemblbacteria:AGN75957(transcript)|ensemblbacteria:TP_0785(gene)|ensemblbacteria:TPANIC_0785(gene)|refseq:WP_010882230.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0785; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:chqFJ3kK0mEzje0a+OWUPBenHcA243276 intact-crc:3AC69311E4F24620|rigid:opx4+Kv7UoAXDepO4FZERdTx7zs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83764 uniprotkb:O83463 intact:EBI-1593570|ensemblbacteria:AAC65749|ensemblbacteria:AGN75957 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83764_trepa(display_long)|uniprotkb:TP_0785(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593575|imex:IM-9152-1532 author score:0.476837049 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005653(OstA-like protein)|ensemblbacteria:AAC65749(transcript)|ensemblbacteria:AGN75957(transcript)|ensemblbacteria:TP_0785(gene)|ensemblbacteria:TPANIC_0785(gene)|refseq:WP_010882230.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0785; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:chqFJ3kK0mEzje0a+OWUPBenHcA243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:ADAE8AE0D4C74BAF|rigid:BEikQ58PDB8g5JUXZvjZQ7jzNek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83764 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1593570|ensemblbacteria:AAC65749|ensemblbacteria:AGN75957 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83764_trepa(display_long)|uniprotkb:TP_0785(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593581|imex:IM-9152-1533 author score:0.353373057 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR005653(OstA-like protein)|ensemblbacteria:AAC65749(transcript)|ensemblbacteria:AGN75957(transcript)|ensemblbacteria:TP_0785(gene)|ensemblbacteria:TPANIC_0785(gene)|refseq:WP_010882230.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0785; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:chqFJ3kK0mEzje0a+OWUPBenHcA243276 intact-crc:EBF8A4488D23D54B|rigid:wr2TAKmHgaHC9cMIAVrMJbxdzek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83764 uniprotkb:P21992 intact:EBI-1593570|ensemblbacteria:AAC65749|ensemblbacteria:AGN75957 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83764_trepa(display_long)|uniprotkb:TP_0785(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593587|imex:IM-9152-1534 author score:0.3001576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005653(OstA-like protein)|ensemblbacteria:AAC65749(transcript)|ensemblbacteria:AGN75957(transcript)|ensemblbacteria:TP_0785(gene)|ensemblbacteria:TPANIC_0785(gene)|refseq:WP_010882230.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0785; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:chqFJ3kK0mEzje0a+OWUPBenHcA243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:424AC62B6CFAAF73|rigid:0AbcYzfvq3e4Rd4UzC7JIDX+o2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83764 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1593570|ensemblbacteria:AAC65749|ensemblbacteria:AGN75957 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83764_trepa(display_long)|uniprotkb:TP_0785(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593593|imex:IM-9152-1535 author score:0.057022822 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005653(OstA-like protein)|ensemblbacteria:AAC65749(transcript)|ensemblbacteria:AGN75957(transcript)|ensemblbacteria:TP_0785(gene)|ensemblbacteria:TPANIC_0785(gene)|refseq:WP_010882230.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0785; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:chqFJ3kK0mEzje0a+OWUPBenHcA243276 intact-crc:AFD87582C9B907ED|rigid:yO/XD4UtAsa9hAPBe3nPwVQ/59U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83801 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593599|imex:IM-9152-1536 author score:0.647169394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 intact-crc:BCF5AB0A3A4C1A0A|rigid:aOEOxEr8eTxgIV0tJPZgqgsT200 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83801 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593608|imex:IM-9152-1537 author score:0.603670339 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0412|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 intact-crc:9AB310E6140E3E42|rigid:XmUWBT/hrFebYRIzgGxd33ALmHM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83634 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593617|imex:IM-9152-1538 author score:0.551170744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:6A2D5EC86CDC1B23|rigid:y9Pkc75J8f5WA8D3+ZRtZ2ecG/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83542 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593623|imex:IM-9152-1539 author score:0.504236091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:781D15F6813DBBC9|rigid:OTHEJ8Y8Wm1F0titJeEa2YHqsyg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83532 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593629|imex:IM-9152-1540 author score:0.430649313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:3E298D1D84001154|rigid:X1HKKX8JlYh8gO/W9NrOnUnaUTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83801 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593635|imex:IM-9152-1541 author score:0.410966854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 intact-crc:4BD7206F110274F4|rigid:9ImTGxZU5miM65k1k0whxjTmTWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83801 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593647|imex:IM-9152-1543 author score:0.300572225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 intact-crc:9DFF14E2E3FEA4AA|rigid:u8S9qiV7hLc3EmVXDgllzkgRs1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:P21992 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593653|imex:IM-9152-1544 author score:0.238278583 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:F4084BC6017F7C00|rigid:0fIWXXVJqL6chxTJfAnAdxmTOR8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83805 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593641|imex:IM-9152-1542 author score:0.404465623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:D258014AD3B9601B|rigid:DL870UaM8zLUSE/3V9ojrD2qDDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83531 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593659|imex:IM-9152-1545 author score:0.20487464 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:4202FD5D461A64D0|rigid:L6HJWYdGmVTRzDJylZeH3iVymj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83801 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593665|imex:IM-9152-1546 author score:0.175873531 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 intact-crc:94D8E1F31A3068B6|rigid:xEcv11Q3iGP5GNKsqf7rLI36EBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83877 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593677|imex:IM-9152-1548 author score:0.080690608 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:BEE72FA65818BC1B|rigid:QcskONqkbUgfjX6qZODbG3tkYmU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83574 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593671|imex:IM-9152-1547 author score:0.121818779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:D3AC65F6FA07AD38|rigid:Lcns7fj3rBBuWRF+ABu1M/Y5fzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83767 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593689|imex:IM-9152-1550 author score:0.046296122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:45D3214E3730498E|rigid:eH29JqxERsQBWGDl0UophOzUkrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83667 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593683|imex:IM-9152-1549 author score:0.067770131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:F562078EAE993F7F|rigid:ETwtmJcFykMon3k4cqwrmDiH24c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83954 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593695|imex:IM-9152-1551 author score:0.013156781 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:C894812FCEFB8D1A|rigid:uRqEHGejDntKAhh56SiIRcKguXQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83801 uniprotkb:O83958 intact:EBI-1593603|ensemblbacteria:AAC65795|ensemblbacteria:AGN75999 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83801_trepa(display_long)|uniprotkb:TP_0829(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593701|imex:IM-9152-1552 author score:0.000788623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018708|ensemblbacteria:AAC65795(transcript)|ensemblbacteria:AGN75999(transcript)|ensemblbacteria:TP_0829(gene)|ensemblbacteria:TPANIC_0829(gene)|refseq:WP_010882273.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0829; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ogPDuVerPOcQ+6NGF/KVhzN9YpA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:3278269672387808|rigid:VBDlIJI0ErQHp4eqg5vwvxuM/Ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83480 uniprotkb:O83925 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593710|imex:IM-9152-1553 author score:0.64564172 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0467|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:F8379078A53B5EF2|rigid:95Eusg8WXxFhViHh9xJRNHloqiA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96115 uniprotkb:O83925 intact:EBI-1198311|uniprotkb:O83197|intact:EBI-1581520|ensemblbacteria:AAC65150 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:ruvb_trepa(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:TP_0162(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593716|imex:IM-9152-1554 author score:0.639458295 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|refseq:WP_010881609.1|ensemblbacteria:AAC65150(transcript)|ensemblbacteria:TP_0162(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009432"(SOS response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0162|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pKRvyji0nd7AkF5U2AAlQB988W0243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:09084135E422621B|rigid:oyBq950MywfWubYOlDEjH99PDHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83284 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1198794|intact:EBI-1585107|ensemblbacteria:AAC65253 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:y260_trepa(display_long)|uniprotkb:TP_0260(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593722|imex:IM-9152-1555 author score:0.626953387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR003646(Bacterial SH3-like region)|refseq:WP_010881709.1|ensemblbacteria:AAC65253(transcript)|ensemblbacteria:TP_0260(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0260|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:6FLFtFh4813Hhv9UyfYZj2+9nGg243276 intact-crc:2AEEEF05A2C41BC2|rigid:Bmmd1zREat6MGIS1bnSQRGztH5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83126 uniprotkb:O83925 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593728|imex:IM-9152-1556 author score:0.607878048 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:E009E271A5E25F5A|rigid:EBZgoQxWFQE+699lgCblhNVsuXU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83925 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593740|imex:IM-9152-1558 author score:0.558359276 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:5BAF4328903A9550|rigid:/G9WGLXU9MHzmz9vXCxIPkudqEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83051 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1198241|intact:EBI-1582345|ensemblbacteria:AAC64998 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:gyra_trepa(display_long)|uniprotkb:gyrA(gene name)|psi-mi:gyrA(display_short)|uniprotkb:TP_0005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593734|imex:IM-9152-1557 author score:0.601442441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR005743(DNA gyrase, subunit A)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|refseq:WP_010881455.1|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|ensemblbacteria:AAC64998(transcript)|ensemblbacteria:TP_0005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0046677"(response to antibiotic)|interpro:IPR035516 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:6wyB1LWK7Ht42imzj0bLSNv95PA243276 intact-crc:A3BDD7181EB3295C|rigid:okreICL+tS28YzNKH8UP3i4XOBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:P45685 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593746|imex:IM-9152-1559 author score:0.542193571 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:FEB88B0F4DE557C5|rigid:up0LeT9gc1jTy6xpXzsTOu64HGo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83804 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593752|imex:IM-9152-1560 author score:0.415238646 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:AF966C52F5F9FFC6|rigid:I/51eUp74XJKrNEN8O22p7G7e9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83312 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593758|imex:IM-9152-1561 author score:0.194779272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:6793D99951B838E8|rigid:PvjrRbUXDxEmSED58mckcfOSIBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83574 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593764|imex:IM-9152-1562 author score:0.135871832 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:DD1F4DBDD7D30091|rigid:2kqRWPXsSO+uLy0RgQj4N5Z4FU4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83925 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593770|imex:IM-9152-1563 author score:0.090487982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:CDAF846FED4BE914|rigid:4DNl/9NwabX9RniPje1LFeTbcdM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83925 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593776|imex:IM-9152-1564 author score:0.043586496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:D5D156A09A07F872|rigid:7Cein7EMp5QPD6Q/FPZVbxjbr84 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83925 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593782|imex:IM-9152-1565 author score:0.017919089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:8F45A61983F57427|rigid:/+s2MGIGUWKSd9X/EaDTuF8aWMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83925 uniprotkb:O83954 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593788|imex:IM-9152-1566 author score:0.014887052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:EF8710EEDE59EF3C|rigid:MpWpRtMoZrEQAE0Nk077DHuhDak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83925 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593794|imex:IM-9152-1567 author score:0.000893809 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0959; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:31CDA8C8412ACAC4|rigid:5L9Ks0RzkwXCmIaL58Ps4+YIgRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83310 uniprotkb:O83475 intact:EBI-1588258|ensemblbacteria:AAC65268 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593800|imex:IM-9152-1568 author score:0.64552886 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:EE8044D56CDE6F16|rigid:RgX4okCXpFyr0eH2WLS96EbMcYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83647 uniprotkb:O83475 intact:EBI-1582557|ensemblbacteria:AAC65615 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593806|imex:IM-9152-1569 author score:0.64552886 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:AFBD40AD3E96F294|rigid:J7gOBMYGOJnrTzqvfxfdMQzasYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:Q08255 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593812|imex:IM-9152-1570 author score:0.607760467 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:22937430214C19FF|rigid:D4D+CSx1JRosU7clPMbkX/97JTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83475 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593818|imex:IM-9152-1571 author score:0.528678094 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:B99D7937B3B5D577|rigid:JFTqcuf9xaLVOTXqYNwmAaJ/5Fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83475 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593824|imex:IM-9152-1572 author score:0.488328011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:CFC8D871DCAB87F1|rigid:d6fjhQXGgUQ68i1Y469eUSMvtBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83475 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593836|imex:IM-9152-1574 author score:0.402108192 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:A0344739F05CC601|rigid:XUp++hGKqJBjTSF0TUVL/WptrXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83398 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593842|imex:IM-9152-1575 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:F93F1BF83BE1E571|rigid:Mi6786R1aZo6qxGnQ0up+xPBnaE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83475 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593830|imex:IM-9152-1573 author score:0.468177107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:783E83D09979248A|rigid:EAJsrbkRNsgIJKz5N6lEwcMk7VU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83475 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593848|imex:IM-9152-1576 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:D29B025AE08C5D71|rigid:g9e7KrMsoRLa4775wufD5WB4hWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83767 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593854|imex:IM-9152-1577 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:D22056AD33A86464|rigid:SCrc5565CpF7aZcaEhz8P4Jn2+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83282 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593866|imex:IM-9152-1579 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:F96BC136665FAEDE|rigid:Jf0xejQzJjUc9bqWLWym4yUx8Zg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83745 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593860|imex:IM-9152-1578 author score:0.052129895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0462; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:8EAA04A6F979C0F3|rigid:rdcu7FuHUOnqWUqpACwF1jYlD2k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83647 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593872|imex:IM-9152-1580 author score:0.64552886 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:0D210E43A04D293E|rigid:xelqEtvHZ18v98cT0WcB6ba28zA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83185 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593878|imex:IM-9152-1581 author score:0.508516923 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:BDD1CBB39A52FC3A|rigid:AEZI3PghWX2XzpwSgNhfmhePz8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83565 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593884|imex:IM-9152-1582 author score:0.488328011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:2A2E56E840365B2B|rigid:6tY5XA2lo8t0Sc+oXlBtSG83e2E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83185 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593890|imex:IM-9152-1583 author score:0.402108192 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:45D2C9A06CC11ADB|rigid:NagncYxSAARTQ1W63f9bTHdt9Hc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83185 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593896|imex:IM-9152-1584 author score:0.3702135 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:D483411D9CDB264B|rigid:b/mNW7u/GJLYfcNzJsbnH+/dck8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83982 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593902|imex:IM-9152-1585 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:002A1ACAB90A19BC|rigid:bzJJ1Zmoex1Srm3ng7VdxX0HX5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83531 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593908|imex:IM-9152-1586 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:377D8CC37C1181AB|rigid:Czk7nNI5tvYFoj0+frUiFUtEEjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83185 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593914|imex:IM-9152-1587 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:F5438A7E88F84103|rigid:TdoRn1AvJwAtut5N5wHw4huTi4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83185 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593920|imex:IM-9152-1588 author score:0.107194186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:83770EA30CFBA0F2|rigid:BbjrX6DOASia/BB3B/pvRxUKUEM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83185 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1586442|ensemblbacteria:AAC65142 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593932|imex:IM-9152-1590 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 intact-crc:37C6D834AF35B8BE|rigid:pJWHQk28JsoGGh4peAJ8SFf7X74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83958 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593938|imex:IM-9152-1591 author score:0.00107844 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:19DDF98E0AF90524|rigid:otmXucZcRoWyTgYeiuTtEvVdZfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83185 uniprotkb:O83667 intact:EBI-1586442|ensemblbacteria:AAC65142 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y150_trepa(display_long)|uniprotkb:TP_0150(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593926|imex:IM-9152-1589 author score:0.090447395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65142(transcript)|ensemblbacteria:TP_0150(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0150; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8z8xVt8/JsgZwLAdxUgiomoIZHk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:1571E02C6117F160|rigid:/zEHmck5WuMr8TORquwUpjdAY/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83239 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593944|imex:IM-9152-1592 author score:0.645303091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:D9017511A99A42AE|rigid:98/Kl9OGkVVeZPFc6ihQKMD8AGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83532 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593950|imex:IM-9152-1593 author score:0.601087672 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:10F7BC5B68E3290E|rigid:j9Mo+k3N6EjBFWuKOF134fl9KAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83239 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593956|imex:IM-9152-1594 author score:0.369983517 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:4AD852440836313F|rigid:KwBhyRrzca0lVwXUIMBHgLEwlvA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83239 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593962|imex:IM-9152-1595 author score:0.339191351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:A7FA9D390A55C21F|rigid:FzVg2WtO1qsvppowhOXF41SjwAA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83282 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593974|imex:IM-9152-1597 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:DD821D4D8FA0AE1D|rigid:R1F4Uw3OyYNYGKQ6+5mM8aalVug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83239 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593968|imex:IM-9152-1596 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0209; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:A5852025986CF4C1|rigid:gOLTiI7A2epaO4ql3n7f3g0KBc4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83103 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593980|imex:IM-9152-1598 author score:0.645190182 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0064; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 intact-crc:B0A1AC0134701468|rigid:7Q3ppbS6CEzWxWAxEde07vthWdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83103 uniprotkb:O83305 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593986|imex:IM-9152-1599 author score:0.42130928 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0064; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:9096C73BF14AF751|rigid:UYroSvyal4qhGFR3jVg1H5gseDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83103 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1198259|intact:EBI-1581772|ensemblbacteria:AAC65064 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y064_trepa(display_long)|uniprotkb:TP_0064(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593992|imex:IM-9152-1600 author score:0.414759643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") refseq:WP_010881513.1|ensemblbacteria:AAC65064(transcript)|ensemblbacteria:TP_0064(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0064; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:WAesUNGA5UU/IgN/dGj8IMo8KH8243276 intact-crc:2041CC644F7ABA9B|rigid:s8fh5lpgrLWNl5/nKLWZpfzE8dc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83478 uniprotkb:O83666 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1593998|imex:IM-9152-1601 author score:0.643510429 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:492B852593A51F0B|rigid:MPa/ku0kDHyF9FO6+GDEfkfVRAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83666 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594004|imex:IM-9152-1602 author score:0.627812618 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:C46F5AEBC5292289|rigid:udCpBuTnx+UnscoB5EfMi8/jDys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83634 uniprotkb:O83666 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594010|imex:IM-9152-1603 author score:0.612069792 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:71A9DD615E066B7E|rigid:h3ZZhvhsxQTpXNlJ/K2Wut1lIws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83666 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594016|imex:IM-9152-1604 author score:0.586212783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:A2752169A654F40E|rigid:fgrzjMeAA12f/LnQ5hzL89lQ+3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:O83413 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594022|imex:IM-9152-1605 author score:0.387606503 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:DC2D4046A4595474|rigid:DtAUJnSYWP7FNn9qLwJcZYv8mes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83666 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594028|imex:IM-9152-1606 author score:0.274707055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:CF2063D67945D5EE|rigid:laLlbgBAQZioFs3CM9sSLRXO2Cg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83666 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594034|imex:IM-9152-1607 author score:0.248714004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:DF74034FE62C4B68|rigid:Xp9WkPvXLUlBGQQRHlKl/w4VpwU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:O83312 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594040|imex:IM-9152-1608 author score:0.215186659 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:C0C06C211498CB02|rigid:O6jK5ES7f6v5IuV3cpI4NQS7MVA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83666 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594052|imex:IM-9152-1610 author score:0.151266804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:2AF73EC2A0AB9E24|rigid:unwNXLXBRNwPUCzOkHWIESqVR00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:O83099 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594046|imex:IM-9152-1609 author score:0.210674823 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:4E2521080D2461C4|rigid:ntiC/EyjNR88SpSqt+gd5XKy+KA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83666 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594064|imex:IM-9152-1612 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:03CE3AA78279290E|rigid:aPko4TET/HkeKk/vyV+gkXCmUGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83666 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594070|imex:IM-9152-1613 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:05D18E4B7AFA7CBD|rigid:rhFwdcA1C7GzVd1AZnKApRJGCKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83666 uniprotkb:O83667 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594058|imex:IM-9152-1611 author score:0.08542356 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0660; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:A1D2C1D88906BE07|rigid:cfHenFulivI5XrPuIty3Z5tcKeA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07884 uniprotkb:O83773 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594076|imex:IM-9152-1614 author score:0.641486887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0727|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:BA16F51050181077|rigid:rQErEO1a8Y8q7agdLnn3Rc1gGAo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83773 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594082|imex:IM-9152-1615 author score:0.590599372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:79DDD2024A57F48D|rigid:B1wwtt3f7kcLur1tsIMUnxQwSHo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O66106 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594088|imex:IM-9152-1616 author score:0.551048718 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:6F2451370275057E|rigid:bhMSLESDGEWHCIxGc9Jcd4nRfYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83773 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594094|imex:IM-9152-1617 author score:0.537694317 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:2E9032FD011D157B|rigid:gATQmXh9McoclkXKUW1JSdM5HhM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83773 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594100|imex:IM-9152-1618 author score:0.341501451 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:BEB55E3F89246AD8|rigid:PXGsC3XQFOErk3rf47DEWu2BGcc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83305 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594106|imex:IM-9152-1619 author score:0.267645258 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:84817012C2E77905|rigid:5sCuwtgfAHNZf6ysDaqTV59kH9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83773 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594112|imex:IM-9152-1620 author score:0.26240127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:908276F980CCDB76|rigid:1V5LXIabOmNc/Lj1YEIXIAsR7SY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83773 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594118|imex:IM-9152-1621 author score:0.26240127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:B3EAE44352284F65|rigid:lpJyfIYd5NAsURWvbHVLbkwHEUk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83969 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594130|imex:IM-9152-1623 author score:0.21826134 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:E377F6A77C21F98F|rigid:liuFs9Ht7admV9Cekkak7IA3GnU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83531 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594124|imex:IM-9152-1622 author score:0.237191817 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:56E05794436CDBB9|rigid:4tYAncZKS8Mw8dRPmFqvZTtyNRI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:P21992 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594136|imex:IM-9152-1624 author score:0.196164711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:757B4A1931F09F1C|rigid:czU8uhS9FRiG0DNk0yDBdCv+BK0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83667 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594142|imex:IM-9152-1625 author score:0.080654025 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:6093B08D3EF0D333|rigid:/XZCwS01OygQJFXUkSz72EEuGVw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83773 uniprotkb:O83767 intact:EBI-1585034|ensemblbacteria:AAC65767 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594148|imex:IM-9152-1626 author score:0.055339904 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:74CCCFD09CEB0ABC|rigid:2KXW6AcdCVZhTbYJos8GzXLNAhE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83773 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1585034|ensemblbacteria:AAC65767 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y795_trepa(display_long)|uniprotkb:TP_0795(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594154|imex:IM-9152-1627 author score:0.015834394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65767(transcript)|ensemblbacteria:TP_0795(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0795; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:2XabOAwBAoHxklegNBO8ua4+jtY243276 intact-crc:3FC5A4248B0DFA95|rigid:EJ/aB1ZET4adLKDFwqIYdPzG8N4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08255 uniprotkb:O66105 intact:EBI-1584220|ensemblbacteria:AAC65647 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594170|imex:IM-9152-1629 author score:0.577519459 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:5DBDFEA51F307040|rigid:OlcTnuQlh9ZPpPboIIDawX6Ljbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07884 uniprotkb:O66105 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594164|imex:IM-9152-1628 author score:0.641486887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0727|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:28D2FD2FB158754D|rigid:RQbCOt6Gd4pAk/8x5MzjD5KOAa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83565 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594182|imex:IM-9152-1631 author score:0.457104252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:35FBAAAC4BBFF488|rigid:rJCfTyfn/ksA0R6dv1LROzMvOFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O66105 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594176|imex:IM-9152-1630 author score:0.517566882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:8AEAF8913DCDE51A|rigid:EQeKN6QnyxJ7pSDXMEu1/4ekokc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83670 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594188|imex:IM-9152-1632 author score:0.450431281 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:1DD62F0B1A092BB7|rigid:7ukGGnc1VDglOnXAX6DrZceWfog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O66105 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594194|imex:IM-9152-1633 author score:0.450431281 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:74159A2F15A09585|rigid:FneVTL+UzOWEcGKlZVEVfadd/0A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83738 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594200|imex:IM-9152-1634 author score:0.437141026 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:47C898AA6E1EB96C|rigid:BrLDMLeNt/Ik/uksyXUsHpLW6pE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83305 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594206|imex:IM-9152-1635 author score:0.267645258 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:39952769832034E3|rigid:4vbv/oo61DNP7QjuSoMNp07EUH4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O66105 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594212|imex:IM-9152-1636 author score:0.196164711 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:4FCC5EA374130590|rigid:yDd+GuxCR6lfrSEy/WTRhOqKESg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O66105 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594224|imex:IM-9152-1983 author score:0.095778469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:D57F28819190F900|rigid:Gx9S+Asxpbac1v+yfG7+cAaExN4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83574 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594218|imex:IM-9152-1637 author score:0.14339739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:D2FBC5D36BBA9B8B|rigid:pZU33w5wIsaoN2jEin27mBofsOs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O66105 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594230|imex:IM-9152-1984 author score:0.080654025 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:78D7280CF4BE82C8|rigid:eEJM8AE1V/pakNyfZBMSU8kepN4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O66105 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1594160|ensemblbacteria:AAC65904 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594236|imex:IM-9152-1985 author score:0.055339904 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 intact-crc:842A56EEF21555A8|rigid:hs8nQbMExY5HcobRYYwSGVUQAAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66105 uniprotkb:O83958 intact:EBI-1594160|ensemblbacteria:AAC65904 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:ppib_trepa(display_long)|uniprotkb:ppiB(gene name)|psi-mi:ppiB(display_short)|uniprotkb:ppi(gene name synonym)|uniprotkb:TP_0947(locus name)|uniprotkb:Rotamase(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594242|imex:IM-9152-1986 author score:0.000951547 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020892|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|ensemblbacteria:AAC65904(transcript)|ensemblbacteria:TP_0947(gene)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|refseq:WP_010882390.1|interpro:IPR029000|interpro:IPR044666 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0947; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GSfYyb7tm9JzwVKJ9MQH6kbiDWo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BF1681FC1E3A61B0|rigid:6CvOWnGUQw14Th4sN7qvGL+ZxZg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83156 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1594258|ensemblbacteria:AAC65109|ensemblbacteria:AGN75338 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:o83156_trepa(display_long)|uniprotkb:TP_0119(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594254|imex:IM-9152-1988 author score:0.637424712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|ensemblbacteria:AAC65109(transcript)|ensemblbacteria:AGN75338(transcript)|ensemblbacteria:TP_0119(gene)|ensemblbacteria:TPANIC_0119(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010881568.1|interpro:IPR035906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0119|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:yoC6gxeiibRm2jnHyMU4vUIROaI243276 intact-crc:AABAA808CB7764CE|rigid:KlL+0lCRwh8/fJUQpmW9WHohu7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83854 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1583647|ensemblbacteria:AAC26574|ensemblbacteria:AGN76053 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:o83854_trepa(display_long)|uniprotkb:TP_0884(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594248|imex:IM-9152-1987 author score:0.641224506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005495(Predicted permease YjgP/YjgQ)|ensemblbacteria:AAC26574(transcript)|ensemblbacteria:AGN76053(transcript)|ensemblbacteria:TP_0884(gene)|ensemblbacteria:TPANIC_0884(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0884; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:0NJ4SPoxnLNgc6nou7DoPdZDgLw243276 intact-crc:BC94DC7546B755E7|rigid:0fK24UQeYJHPUwBxpsAlypM4x2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83205 uniprotkb:O83996 intact:EBI-1594270|ensemblbacteria:AAC65165 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:y175_trepa(display_long)|uniprotkb:TP_0175(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594266|imex:IM-9152-1989 author score:0.637424712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002826(Protein of unknown function DUF115)|ensemblbacteria:AAC65165(transcript)|ensemblbacteria:TP_0175(gene) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0175|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LRgR/vj8QTpvXyx7TeI73xK49G0243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:A02AED627CD0FBB6|rigid:ahNsVPML+AvdPOMY77ylq2XPRLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83996 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594275|imex:IM-9152-1990 author score:0.355840805 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:686E5DE8842F3559|rigid:AKXeQD7EZesVCxYmcBk93/lafso false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83463 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594281|imex:IM-9152-1991 author score:0.313906279 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:9DF82D4B3CF550AF|rigid:R4/ljBPfqI1pQOX/B8RcGL+lLkc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:P21992 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594293|imex:IM-9152-1993 author score:0.271488039 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:C04DE69A6AA8891E|rigid:Wz62SQvhja7wEFU5IWSBnxv8iZI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83996 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594287|imex:IM-9152-1992 author score:0.272748469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:CD2A1AED6A915688|rigid:y2jhNKWGe0rJ9U8CG/qK5R9WyQo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83982 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594299|imex:IM-9152-1994 author score:0.238879139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:D970F342E9C91EBB|rigid:tk63wVFEJE2jOsjWjIkkNmaWjm8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83996 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594305|imex:IM-9152-1995 author score:0.197635793 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:14F1AAE2FF5FD721|rigid:bm5W3FYhcejwhMUEeo1LsiG2nLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83996 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594311|imex:IM-9152-1996 author score:0.185139981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:51E487688415B73D|rigid:gFeMxBgGNJNaP8F4yk4OXgmzPrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83996 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594317|imex:IM-9152-1997 author score:0.176364806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:6E78F9CF387C435B|rigid:PrpfezJPKwOixmb3Hctpp6wQKOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83413 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594323|imex:IM-9152-1998 author score:0.099760006 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:65FA5CF132B48CA8|rigid:d3AxmBCCgzwGDuYwRa9JIsbZBws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83877 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594329|imex:IM-9152-1999 author score:0.085462104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:4D86D313F59C4A19|rigid:KbSNjzj1Ce0fXi1vtxs8URPBvo8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83745 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594335|imex:IM-9152-2000 author score:0.057499906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:E807626DBE94B0BD|rigid:SHrbGAC7zrFbdqjcNhX7VuiBhZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83996 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594341|imex:IM-9152-2001 author score:0.016849158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 intact-crc:22096AA5FC57AF27|rigid:v608QZcG4tA9Db6BZXN902XPH60 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83954 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594347|imex:IM-9152-2002 author score:0.013995581 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1F928629198634CF|rigid:8qQoXgTXDnRYO84SPKOLWrw4W/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83996 uniprotkb:O83958 intact:EBI-1594261|ensemblbacteria:AAC65980|ensemblbacteria:AGN76197 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83996_trepa(display_long)|uniprotkb:TP_1033(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594353|imex:IM-9152-2003 author score:0.001184843 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR002641(Patatin)|ensemblbacteria:AAC65980(transcript)|ensemblbacteria:AGN76197(transcript)|ensemblbacteria:TP_1033(gene)|ensemblbacteria:TPANIC_1033(gene)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010882477.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1033; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qLvY1CSWT+Xbtfjt05lqZfNzEDw243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:58920D74DD5B1B79|rigid:BW2Vjn7W2QoY1wXSOZ55YMe/0yY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83424 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1585489|ensemblbacteria:AAC65397 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594359|imex:IM-9152-2004 author score:0.637196683 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 intact-crc:8E3DD739A0739A6E|rigid:hUZbq4a7ORT5la+ALJodoN/TfTo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83098 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594365|imex:IM-9152-2005 author score:0.599091869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:9DAC9B58AC682547|rigid:5zpPn1AqkwJKbRzTZxYlq6+o8Mo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83596 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594371|imex:IM-9152-2006 author score:0.58609313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:904E9F14808F4EDD|rigid:FcpTCFb+FuHn+DOcXS8rLLxHxBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83424 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1585489|ensemblbacteria:AAC65397 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594377|imex:IM-9152-2007 author score:0.539760961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 intact-crc:FD965617E6ED7CC8|rigid:QsGTjM8qgV14M5A+8R/jcDn6hwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83305 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594383|imex:IM-9152-2008 author score:0.319518858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:ACA7D6AD4B898161|rigid:PdHmJzVnv34VjRdzUlueF9nDTPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83424 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1585489|ensemblbacteria:AAC65397 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594389|imex:IM-9152-2009 author score:0.119790274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 intact-crc:757F30407EF244B2|rigid:fgaf12uSFkbnJlyZ7OQ+GXCQEBo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83667 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594395|imex:IM-9152-2010 author score:0.101298891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:0614CFFC8C19D746|rigid:mBjxh+rO0r7W04bTHlFSl/kO0To false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83767 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594401|imex:IM-9152-2011 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:C21A1680B81812DA|rigid:uCQE/eRLQbAMv981LycU3I4uLBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83424 uniprotkb:O83954 intact:EBI-1585489|ensemblbacteria:AAC65397 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594407|imex:IM-9152-2012 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:518E3EA9E04FF70C|rigid:Nv3B+sZn09tXOuDqOLoWO/QuJi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83424 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1585489|ensemblbacteria:AAC65397 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y409_trepa(display_long)|uniprotkb:TP_0409(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594413|imex:IM-9152-2013 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65397(transcript)|ensemblbacteria:TP_0409(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0409; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ha52Z2fwbyOxtnLv1kbSxWKX4cg243276 intact-crc:D61A40AE4A058558|rigid:bvbH6qzQFjrbmUzHE3bWHhqyj1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83106 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594428|imex:IM-9152-2015 author score:0.63603608 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:5516C6BFDE3067D2|rigid:AK1kR1+epf66pgK0eWtLGiZVbCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83356 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1594434|ensemblbacteria:AAC65322|ensemblbacteria:AGN75534 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83356_trepa(display_long)|uniprotkb:TP_0336(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594437|imex:IM-9152-2016 author score:0.607995616 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR004477(ComEC/Rec2-related protein)|ensemblbacteria:AAC65322(transcript)|ensemblbacteria:AGN75534(transcript)|ensemblbacteria:TP_0336(gene)|ensemblbacteria:TPANIC_0336(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881784.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0336|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:fQBM50Sxo7PyPLRObSKg6xcmvuU243276 intact-crc:70822B4958B1DDD5|rigid:oHyZs3rIPjIuhj+tQ85euP+5zfs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83156 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1594258|ensemblbacteria:AAC65109|ensemblbacteria:AGN75338 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83156_trepa(display_long)|uniprotkb:TP_0119(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594419|imex:IM-9152-2014 author score:0.636539362 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|ensemblbacteria:AAC65109(transcript)|ensemblbacteria:AGN75338(transcript)|ensemblbacteria:TP_0119(gene)|ensemblbacteria:TPANIC_0119(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|refseq:WP_010881568.1|interpro:IPR035906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0119; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:yoC6gxeiibRm2jnHyMU4vUIROaI243276 intact-crc:E8E5537C1CA26ED0|rigid:0xLGcPQzaXld5n8SfgF4n/iKdcU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83947 uniprotkb:O83472 intact:EBI-1594449|ensemblbacteria:AAC65937|ensemblbacteria:AGN76146 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:o83947_trepa(display_long)|uniprotkb:TP_0982(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594452|imex:IM-9152-2018 author score:0.607995616 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022764|ensemblbacteria:AAC65937(transcript)|ensemblbacteria:AGN76146(transcript)|ensemblbacteria:TP_0982(gene)|ensemblbacteria:TPANIC_0982(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882426.1|interpro:IPR035952 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0982|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aJ+DcXEG2pmndVqR+BuWAv1zt7c243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:60B7D1253CA75177|rigid:eGsoKx5ITo6aGeI3DDgdWmCt6Gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83844 uniprotkb:O83472 intact:EBI-1587391|ensemblbacteria:AAC65837|ensemblbacteria:AGN76043 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:o83844_trepa(display_long)|uniprotkb:TP_0874(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594443|imex:IM-9152-2017 author score:0.607995616 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65837(transcript)|ensemblbacteria:AGN76043(transcript)|ensemblbacteria:TP_0874(gene)|ensemblbacteria:TPANIC_0874(gene)|refseq:WP_010882317.1 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0874|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DAvZ07QDH2IUmDCpEj1Gx1SGfCY243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:D787AC2CA84F2A6D|rigid:FW9qYhSOkBbSRa6UeMS1nKQ8Qa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83738 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594458|imex:IM-9152-2019 author score:0.528432798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:DEC17EED8851F577|rigid:QnniLM03IJII8OeT45Hww6un2zM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83099 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594464|imex:IM-9152-2020 author score:0.281146504 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:93CEAF6E93B98022|rigid:riOxD+grtaNFYBOakVZZmRE3Ics false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83472 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594470|imex:IM-9152-2021 author score:0.281036856 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:C0FBABA956FC6C0A|rigid:q59UaM2lJvnKDs3DelUgajWmqf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83472 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594476|imex:IM-9152-2022 author score:0.280964712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:9E2306BA7C29ED51|rigid:FyDVx7A0SxeqXQH0GEaqpFl7s7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83531 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594488|imex:IM-9152-2024 author score:0.194856647 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:5E3D9A7BC2E56971|rigid:hGdUfj+bpHBsUjrieadJ8CPQBFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83472 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594482|imex:IM-9152-2023 author score:0.221452594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:0E8B44E344099AD4|rigid:Abrd8YbAukG/PUqbhKU1TNeDVOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:P21992 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594500|imex:IM-9152-2026 author score:0.15961996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:F3D0940DE0F71E77|rigid:R65/zgnYsunIT6wjLfEMKVF01Qk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83472 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594494|imex:IM-9152-2025 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:80399F29E41AE687|rigid:zd2UjYytV5vQO+msxKHTRswDwqY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83927 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594506|imex:IM-9152-2027 author score:0.142378866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:B6687ECC26CB4DBB|rigid:MWTMrmxI02eNgMVIWSqDpETj03g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83574 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594512|imex:IM-9152-2028 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:F1C5EF63370E369F|rigid:TtUTQoEjqCmjiccqVMaDEsk6Aa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83767 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594524|imex:IM-9152-2030 author score:0.043607063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:54B4B2AFA533A8A9|rigid:VkXsugi9FY6RUJUDurjfRut7c3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83472 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594518|imex:IM-9152-2029 author score:0.068923443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:BB543862DA14F0FB|rigid:edbT+UFnGvieamLhFZwAB+vVNVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83472 uniprotkb:O83282 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594530|imex:IM-9152-2031 author score:0.014894287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9DC9DD93C0CCE809|rigid:S40Zhcix/BahxrUfBkoPgyTYqis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83472 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1594425|ensemblbacteria:AAC65447|ensemblbacteria:AGN75653 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83472_trepa(display_long)|uniprotkb:TP_0459(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594536|imex:IM-9152-2032 author score:0.001047434 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR018496|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65447(transcript)|ensemblbacteria:AGN75653(transcript)|ensemblbacteria:TP_0459(gene)|ensemblbacteria:TPANIC_0459(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986|interpro:IPR042092|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0459; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:4fWampR47uE8kjViJPu0n3PcC0E243276 intact-crc:00B931A300298C36|rigid:AoKfPEMDfVe04aT9ANeh7RJQzIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83261 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594542|imex:IM-9152-2033 author score:0.635157622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:320B9E11AE0DEB34|rigid:vQXWcVut6f1FMwttgE2AsY5Mml4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83939 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594554|imex:IM-9152-2035 author score:0.570816448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:36EC7FD70B473BD5|rigid:Y/Ma9cEpgm+DHcOd0qh+hX3f2Kw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83911 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1587757|ensemblbacteria:AAC65900 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594548|imex:IM-9152-2034 author score:0.628896407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 intact-crc:797F76BFBD84EE6F|rigid:n+zm6xC4doXKdzUguuV79W+dVKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83627 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594560|imex:IM-9152-2036 author score:0.564208645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:9D4D4B303DB15F05|rigid:fgNYhr8R/Q1rmk9JKokDfdW8CEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83099 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594572|imex:IM-9152-2038 author score:0.232267228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:5ECF8B12BCC0AAE3|rigid:qHv2hSz5PXvohElIGLnS5RG9VSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83532 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594566|imex:IM-9152-2037 author score:0.524162585 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:63E7EF3BB7450605|rigid:UmyxleyrdKfbgyrRds+pcsThX6A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83911 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1587757|ensemblbacteria:AAC65900 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594578|imex:IM-9152-2039 author score:0.204713982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 intact-crc:9F15C37476F52113|rigid:adp/NK+SOfV5S7tib4O/WARb90k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83574 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594584|imex:IM-9152-2040 author score:0.168066845 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:539045763BDCBFE7|rigid:ARk6kfdqPjrqkcgxDr+hlhQ+0WY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83911 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1587757|ensemblbacteria:AAC65900 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594596|imex:IM-9152-2042 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 intact-crc:7E68067523E5A48D|rigid:DO8xxFxZsXez2SChRw3MZMjhXJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83911 uniprotkb:O83877 intact:EBI-1587757|ensemblbacteria:AAC65900 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594590|imex:IM-9152-2041 author score:0.113339703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:9399E0F9B51795E6|rigid:DOWeWdf65x4d+JIKzWoDD3iUuSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83733 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1594612|ensemblbacteria:AAC65729 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594608|imex:IM-9152-2044 author score:0.63504331 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 intact-crc:EAA60738991E4294|rigid:qyO40dH2K+/Mf1P92C3yD3QvvTc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83911 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1587757|ensemblbacteria:AAC65900 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y941_trepa(display_long)|uniprotkb:TP_0941(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594602|imex:IM-9152-2043 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65900(transcript)|ensemblbacteria:TP_0941(gene)|refseq:WP_010882384.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0941; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Th/JkRvQG9DLZXnKtaKFfmI891I243276 intact-crc:5FF67FBC64D4EA05|rigid:klaqqgFZZGRU36eVCgS9W5izbNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83733 uniprotkb:O83099 intact:EBI-1594612|ensemblbacteria:AAC65729 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594617|imex:IM-9152-2045 author score:0.267451934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:B7B25DDFEEAFBF36|rigid:myVwwWet4sYmKr2paDRvCol9s+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83733 uniprotkb:O83927 intact:EBI-1594612|ensemblbacteria:AAC65729 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594623|imex:IM-9152-2046 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:CDE360E556622301|rigid:BzNQEIRb9JBwBW+zrsSJe2Go12A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83733 uniprotkb:O83574 intact:EBI-1594612|ensemblbacteria:AAC65729 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594629|imex:IM-9152-2047 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:37E3564B8B6A4DBD|rigid:NXa3VdLbiylXmqklBn4/jhkqRpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83733 uniprotkb:O83877 intact:EBI-1594612|ensemblbacteria:AAC65729 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594635|imex:IM-9152-2048 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B1FEFBB54220C063|rigid:p6EGUgilGMEIM0JCciLdcKwChz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83733 uniprotkb:O83413 intact:EBI-1594612|ensemblbacteria:AAC65729 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594641|imex:IM-9152-2049 author score:0.121660562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:53C367BF9501DFFB|rigid:dfAE6LrYpcCzuK+dddMoJVrCrr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83733 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1594612|ensemblbacteria:AAC65729 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594647|imex:IM-9152-2050 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 intact-crc:FECF56A07818B888|rigid:cx7qsXcd2P2mB+v2fxRfJWhFXcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83189 uniprotkb:O83239 intact:EBI-1587618|ensemblbacteria:AAC65144 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594659|imex:IM-9152-2052 author score:0.634928983 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0154; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:295149B0D0FAA294|rigid:fY/ZLV+jDP8IroyTFlE2J93o5Lo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83733 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1594612|ensemblbacteria:AAC65729 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y752_trepa(display_long)|uniprotkb:TP_0752(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594653|imex:IM-9152-2051 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR007730(Sporulation/cell division region, bacteria)|ensemblbacteria:AAC65729(transcript)|ensemblbacteria:TP_0752(gene)|go:"GO:0042834"(peptidoglycan binding)|refseq:WP_010882197.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0752; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:fhlvBmg+ETjRT2x3rFie/Wu5ELo243276 intact-crc:0D6ACF0412609E07|rigid:9gGOxiO+jfYHwr9/UciyAV3aEvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83189 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1587618|ensemblbacteria:AAC65144 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594665|imex:IM-9152-2053 author score:0.476837049 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0154; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 intact-crc:DA95A6C8FF7CFCDD|rigid:mMlzIb8MDoc1ttb3IHqL9EOhVZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83189 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1587618|ensemblbacteria:AAC65144 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594671|imex:IM-9152-2054 author score:0.364688885 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0154; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 intact-crc:6F10880C832C1CE2|rigid:bvMxKlrRvUsQ1IMUJlEHS+OY+nE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83189 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1587618|ensemblbacteria:AAC65144 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594677|imex:IM-9152-2055 author score:0.329171391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0154; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 intact-crc:EC3920235AC07EBB|rigid:eqPjyO1xpjX5tZbtIw7xZ8kn2K4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83189 uniprotkb:O83099 intact:EBI-1587618|ensemblbacteria:AAC65144 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83189_trepa(display_long)|uniprotkb:TP_0154(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594683|imex:IM-9152-2056 author score:0.305843263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR006145(Pseudouridine synthase)|interpro:IPR002942(RNA-binding S4)|ensemblbacteria:AAC65144(transcript)|ensemblbacteria:TP_0154(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|interpro:IPR036986 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0154; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4toh+vG8r8YpaSSbwh3GN6zIKVE243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:3A1F93830448EA1F|rigid:heydLMrw5wxG3ecBa9cmipb8SGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83650 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1586873|ensemblbacteria:AAC65618 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:syk_trepa(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0644(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594689|imex:IM-9152-2057 author score:0.634814641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002904(Lysyl-tRNA synthetase, class Ic, archaeal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65618(transcript)|ensemblbacteria:TP_0644(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation)|refseq:WP_010882089.1|interpro:IPR042078 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0644; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:1iKQyXCF8vSJ0ysGig7WLZZXQcw243276 intact-crc:9106E97E1B352640|rigid:KN8ZVW6eOREvGJk5xwF0MvkcJ48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83650 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1586873|ensemblbacteria:AAC65618 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:syk_trepa(display_long)|uniprotkb:lysS(gene name)|psi-mi:lysS(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0644(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594695|imex:IM-9152-2058 author score:0.156878757 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002904(Lysyl-tRNA synthetase, class Ic, archaeal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65618(transcript)|ensemblbacteria:TP_0644(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation)|refseq:WP_010882089.1|interpro:IPR042078 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0644; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:1iKQyXCF8vSJ0ysGig7WLZZXQcw243276 intact-crc:AB8098C74E711E59|rigid:kdTmblcBV08MbLFCKWgVVwtaIjM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83482 uniprotkb:O83805 intact:EBI-1582780|ensemblbacteria:AAC65450 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83482_trepa(display_long)|uniprotkb:TP_0469(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594701|imex:IM-9152-2059 author score:0.634814641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65450(transcript)|ensemblbacteria:TP_0469(gene) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0469; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nAw1P0S86smynE/4ogE1RDNgE24243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:9EF146A0D49B8C5C|rigid:KvfEQx6kTwbF8fqdeaozDTRTE/U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83482 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582780|ensemblbacteria:AAC65450 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83482_trepa(display_long)|uniprotkb:TP_0469(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594707|imex:IM-9152-2060 author score:0.002790209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65450(transcript)|ensemblbacteria:TP_0469(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0469; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:nAw1P0S86smynE/4ogE1RDNgE24243276 intact-crc:99016EB7B1B64A8C|rigid:GAJEYT20uBoZPUVcFa3moBBjEKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83692 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1594713|ensemblbacteria:AAC65661|ensemblbacteria:AGN75872 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83692_trepa(display_long)|uniprotkb:TP_0694(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594716|imex:IM-9152-2061 author score:0.634814641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|ensemblbacteria:AAC65661(transcript)|ensemblbacteria:AGN75872(transcript)|ensemblbacteria:TP_0694(gene)|ensemblbacteria:TPANIC_0694(gene)|refseq:WP_010882139.1|interpro:IPR024185|interpro:IPR037171 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0694; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:J1D19PIw3hT+AdsUhuc8ePDSYg8243276 intact-crc:D635625C5FAEE685|rigid:bbAkBQd6whvLfid7tAnC0L++Tiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83692 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1594713|ensemblbacteria:AAC65661|ensemblbacteria:AGN75872 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83692_trepa(display_long)|uniprotkb:TP_0694(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594722|imex:IM-9152-2062 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR002698(5-formyltetrahydrofolate cyclo-ligase)|ensemblbacteria:AAC65661(transcript)|ensemblbacteria:AGN75872(transcript)|ensemblbacteria:TP_0694(gene)|ensemblbacteria:TPANIC_0694(gene)|refseq:WP_010882139.1|interpro:IPR024185|interpro:IPR037171 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0694; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:J1D19PIw3hT+AdsUhuc8ePDSYg8243276 intact-crc:7156419C609B320E|rigid:IYoM4XkvdTe0KkNCCVTf2Eh9AVs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83894 uniprotkb:O83805 intact:EBI-1594732|ensemblbacteria:AAC65881|ensemblbacteria:AGN76091 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83894_trepa(display_long)|uniprotkb:TP_0924(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594728|imex:IM-9152-2063 author score:0.634814641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044146|interpro:IPR032639|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|ensemblbacteria:AAC65881(transcript)|ensemblbacteria:AGN76091(transcript)|ensemblbacteria:TP_0924(gene)|ensemblbacteria:TPANIC_0924(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|refseq:WP_010882367.1|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR041692|interpro:IPR037027 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0924; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AO8a82SCzKqicrOwOpXJd2yOT4Y243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:7E3FB4F708785E53|rigid:yclPKZLCywdlEgB5Eab6j5YcigQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83894 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1594732|ensemblbacteria:AAC65881|ensemblbacteria:AGN76091 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83894_trepa(display_long)|uniprotkb:TP_0924(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594737|imex:IM-9152-2064 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR044146|interpro:IPR032639|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR023323|interpro:IPR023319|interpro:IPR018974|interpro:IPR006641(Resolvase, RNase H-like fold)|ensemblbacteria:AAC65881(transcript)|ensemblbacteria:AGN76091(transcript)|ensemblbacteria:TP_0924(gene)|ensemblbacteria:TPANIC_0924(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|refseq:WP_010882367.1|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR041692|interpro:IPR037027 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0924; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:AO8a82SCzKqicrOwOpXJd2yOT4Y243276 intact-crc:6441D1E6A9760702|rigid:o093hsXrzFJ6En54BYJx4dPI/o4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83924 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1594747|ensemblbacteria:AAC65914|ensemblbacteria:AGN76123 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83924_trepa(display_long)|uniprotkb:TP_0958(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594743|imex:IM-9152-2065 author score:0.634814641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR010656(TRAP C4-dicarboxylate transport system permease DctM subunit)|interpro:IPR007387(Tripartite ATP-independent periplasmic transporter, DctQ component)|interpro:IPR004681(TRAP dicarboxylate transporter, DctM subunit)|ensemblbacteria:AAC65914(transcript)|ensemblbacteria:AGN76123(transcript)|ensemblbacteria:TP_0958(gene)|ensemblbacteria:TPANIC_0958(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882402.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0958; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:6Dy58GBIS1QbTReMh8B+EtOADtQ243276 intact-crc:E2739817F9D1574A|rigid:NqfQcbbcN/NeA1wIMuWt5rkrP7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83924 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1594747|ensemblbacteria:AAC65914|ensemblbacteria:AGN76123 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83924_trepa(display_long)|uniprotkb:TP_0958(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594752|imex:IM-9152-2066 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR010656(TRAP C4-dicarboxylate transport system permease DctM subunit)|interpro:IPR007387(Tripartite ATP-independent periplasmic transporter, DctQ component)|interpro:IPR004681(TRAP dicarboxylate transporter, DctM subunit)|ensemblbacteria:AAC65914(transcript)|ensemblbacteria:AGN76123(transcript)|ensemblbacteria:TP_0958(gene)|ensemblbacteria:TPANIC_0958(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882402.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0958; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:6Dy58GBIS1QbTReMh8B+EtOADtQ243276 intact-crc:C6A0C171AC0B4D3A|rigid:70TgrmhMNsA5xl8xQCoUK9/EKBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83558 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1594771|ensemblbacteria:AAC65533 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594767|imex:IM-9152-2068 author score:0.630950128 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 intact-crc:533786D46FB9221B|rigid:E1gDlspDsM8TRrrliECudspuOzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83190 uniprotkb:O83887 intact:EBI-1594758|ensemblbacteria:AAC65145|ensemblbacteria:AGN75374 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83190_trepa(display_long)|uniprotkb:TP_0155(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594761|imex:IM-9152-2067 author score:0.63433274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|ensemblbacteria:AAC65145(transcript)|ensemblbacteria:AGN75374(transcript)|ensemblbacteria:TP_0155(gene)|ensemblbacteria:TPANIC_0155(gene)|refseq:WP_010881602.1|interpro:IPR036779 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0155; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K88+uiMAqHN/ZBl32EnppOYoZP4243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:58A2DDD0E3667F44|rigid:VmLQQ6oCFNZA9Xwkvt+ZoV3FcWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83558 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1594771|ensemblbacteria:AAC65533 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594777|imex:IM-9152-2069 author score:0.559750072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 intact-crc:1BA10F08E08613E5|rigid:TnRBIceF2ROIi/3HieU7fzK36g8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83558 uniprotkb:O83459 intact:EBI-1594771|ensemblbacteria:AAC65533 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594783|imex:IM-9152-2070 author score:0.539760961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:C676EFE34C782B9F|rigid:KDToeh2xx7KNphRGj2abCPchoCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83558 uniprotkb:O83463 intact:EBI-1594771|ensemblbacteria:AAC65533 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594789|imex:IM-9152-2071 author score:0.399873643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:ACC8215956BA0C92|rigid:tJRWK+vE0B0xCrF18Q4sBzS1ToQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83558 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1594771|ensemblbacteria:AAC65533 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594795|imex:IM-9152-2072 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 intact-crc:91551F74049B5CC5|rigid:Mi8RexhUv63cZiZuki0rNXcn0YY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83558 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1594771|ensemblbacteria:AAC65533 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594807|imex:IM-9152-2074 author score:0.248621847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 intact-crc:D5DF2C45168D7573|rigid:0NqNYtEzaeTSauMsjy3NmZcB3+4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83558 uniprotkb:P21992 intact:EBI-1594771|ensemblbacteria:AAC65533 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594801|imex:IM-9152-2073 author score:0.291254398 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:017EC1196CEAB05F|rigid:2Md1joStQ/fzJi280QgSlyek2mw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83558 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1594771|ensemblbacteria:AAC65533 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594813|imex:IM-9152-2075 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 intact-crc:754C99C5A4E3E10C|rigid:oktxsbHaysCAasxdY5NzhjniYVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83558 uniprotkb:O83954 intact:EBI-1594771|ensemblbacteria:AAC65533 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594819|imex:IM-9152-2076 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:08A7CC36D88B84B4|rigid:G86lPwYjKAGmys4hKsvJHkDAEYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83558 uniprotkb:O83958 intact:EBI-1594771|ensemblbacteria:AAC65533 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:isph_trepa(display_long)|uniprotkb:ispH(gene name)|psi-mi:ispH(display_short)|uniprotkb:lytB(gene name synonym)|uniprotkb:TP_0547(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594825|imex:IM-9152-2077 author score:0.001653934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003451(LytB protein)|ensemblbacteria:AAC65533(transcript)|ensemblbacteria:TP_0547(gene)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051745"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity)|refseq:WP_010881994.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0547; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZhNZdhmzB7gHt1wzFlfjbPgtuNg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:733F791889D5BCCB|rigid:K+mP3BUPXvBbR/3tXPUdnwhSacU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83260 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1594831|ensemblbacteria:AAC65231 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594834|imex:IM-9152-2078 author score:0.630835265 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 intact-crc:13D444EDE5DBEB38|rigid:vkGIJf6P/k26/uYMCueR9c8r6os false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83260 uniprotkb:O83982 intact:EBI-1594831|ensemblbacteria:AAC65231 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594840|imex:IM-9152-2079 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:C7D3AE189BE87022|rigid:D5b6hivbVZs9ZknRHHRUysj7RKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83260 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1594831|ensemblbacteria:AAC65231 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594846|imex:IM-9152-2080 author score:0.302115441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 intact-crc:D169B48027B47257|rigid:cySA3U1rHCY9CiEaZaV9vaNmYvk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83260 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1594831|ensemblbacteria:AAC65231 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594852|imex:IM-9152-2081 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 intact-crc:5049A8B8F8787CFF|rigid:D0VBvbDQFVN6NsQm+4W+FliKvKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83260 uniprotkb:O83767 intact:EBI-1594831|ensemblbacteria:AAC65231 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594858|imex:IM-9152-2082 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:419B34A1D5AD5B94|rigid:p7f4c65x0lq6O/OmVonZJ+whOOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83260 uniprotkb:O83282 intact:EBI-1594831|ensemblbacteria:AAC65231 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594870|imex:IM-9152-2084 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:0271A5AB8C3CF74F|rigid:IQkpMSv9tq7BBHjbOrDPtwhsvdw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83465 uniprotkb:O83939 intact:EBI-1594876|ensemblbacteria:AAC65442 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594879|imex:IM-9152-2085 author score:0.630835265 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:394F9E9DE7310823|rigid:MUxfqho1FgbO3WoleakGsEOAPSk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83260 uniprotkb:O83745 intact:EBI-1594831|ensemblbacteria:AAC65231 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y232_trepa(display_long)|uniprotkb:TP_0232(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594864|imex:IM-9152-2083 author score:0.06996641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65231(transcript)|ensemblbacteria:TP_0232(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0232; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:00/7bwZeWh/JsKa6t7YxTjpR5xk243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:E9E20BA6818CFD01|rigid:EHCL0+TeZmnUr8jK8Ka16KpwSmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83465 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1594876|ensemblbacteria:AAC65442 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594885|imex:IM-9152-2086 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 intact-crc:ED48746899029339|rigid:TAT3PDU6JgOztAJ1yLn3RZqWPEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83465 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1594876|ensemblbacteria:AAC65442 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594891|imex:IM-9152-2087 author score:0.302115441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 intact-crc:FBF26EF0255E914C|rigid:++O//9Mjpb/HP6bQ6FY5EVuBvMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83465 uniprotkb:O83413 intact:EBI-1594876|ensemblbacteria:AAC65442 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594897|imex:IM-9152-2088 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6877A2842B8D2CA6|rigid:yIJZetXGW451Gs7HGGtF1C/WGbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83465 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1594876|ensemblbacteria:AAC65442 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594903|imex:IM-9152-2089 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 intact-crc:3DBED954FD04E82D|rigid:5ApTf9WAucT+6LRSQ6MesDFUkYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83465 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1594876|ensemblbacteria:AAC65442 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594909|imex:IM-9152-2090 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 intact-crc:2AA4F354B7B41A84|rigid:3rqRWHBsQNehPbed5jrHWlQ+41g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83465 uniprotkb:O83958 intact:EBI-1594876|ensemblbacteria:AAC65442 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y451_trepa(display_long)|uniprotkb:TP_0451(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594915|imex:IM-9152-2091 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65442(transcript)|ensemblbacteria:TP_0451(gene)|refseq:WP_010881899.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0451; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9Ny8da3pg0HVoc6ThPyCPbQ4yMo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:5FB680C15579AB40|rigid:y8wIRLiFNUzuRpIpiaMFMugOZsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83218 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594921|imex:IM-9152-2092 author score:0.630720386 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0188; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:E4D3A2413E0BC68A|rigid:LOrx1JJVZ59Jz+QCjqkPXn0PJe4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83218 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594927|imex:IM-9152-2093 author score:0.630720386 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0188; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:2377757116E3A5A9|rigid:EC3qwTLysRGSow3lteezX2fDxBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83218 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594933|imex:IM-9152-2094 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0188; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:EF7848554D77A118|rigid:IkIlLUTaLP8r0+oyLEP7SQDfgHw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83218 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594939|imex:IM-9152-2095 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0188; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:71E4C3274C17336B|rigid:iPMZPZHrGbl0hlDeLHK7K9Z4p5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83926 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1594945|ensemblbacteria:AAC65915|ensemblbacteria:AGN76125 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:o83926_trepa(display_long)|uniprotkb:Flagellar basal-body rod protein FlgG(gene name synonym)|uniprotkb:TP_0960(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594948|imex:IM-9152-2096 author score:0.630605493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR012834(Flagellar basal-body rod FlgG)|ensemblbacteria:AAC65915(transcript)|ensemblbacteria:AGN76125(transcript)|ensemblbacteria:TP_0960(gene)|ensemblbacteria:TPANIC_0960(gene)|go:"GO:0009426"(bacterial-type flagellum basal body, distal rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010882404.1|interpro:IPR037925 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0960; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:+UvjfLGp4qHlmt0XVfRIK9EGJqQ243276 intact-crc:9DE30FA709EB8062|rigid:LgIflJc/2PolGVCTL2xNBDhjJgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83977 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1583534|ensemblbacteria:AAC65964 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594954|imex:IM-9152-2097 author score:0.628896407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 intact-crc:5CEDF069119D21FE|rigid:n7MdAZ8H+Q78IYrARodQRzORwAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:P96129 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1590491|ensemblbacteria:AAC65657 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594960|imex:IM-9152-2443 author score:0.570816448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 intact-crc:C304F9B33679B13F|rigid:962OTm4IM6oUjR+iFCNE/4AjepM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:P96129 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1590491|ensemblbacteria:AAC65657 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594972|imex:IM-9152-2445 author score:0.483803375 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 intact-crc:DFDA7F143D88D1AC|rigid:pvDSR+0wcF37G+o/Vl2YbrDbGfc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83627 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594966|imex:IM-9152-2444 author score:0.564208645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:9FF5377DB74293E4|rigid:4tQYpPeIM8tExO6lCSF8HEgOz9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83305 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594978|imex:IM-9152-2446 author score:0.306052744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:34D70676E134336F|rigid:zDd0UDXzA+pjyX8FFl1YY4cnCIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83099 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594984|imex:IM-9152-2447 author score:0.232267228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:5C77F75F36336602|rigid:zb8wC81otRXjTakekOcGGRuo1WE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:P96129 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1590491|ensemblbacteria:AAC65657 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594990|imex:IM-9152-2448 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 intact-crc:0E13EEC74C086BB8|rigid:cpJkKC31QKK7PwPUUqKhXm7TRGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83767 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1594996|imex:IM-9152-2449 author score:0.066028043 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:27697F13156FA5C6|rigid:OkEIbcCAcg1szSaOgIiJECuO+xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83745 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595002|imex:IM-9152-2450 author score:0.055314123 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:3E959E3CCDC8A8BD|rigid:oAJeMr6JGawbv3pbClSWi5c0gLM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96129 uniprotkb:O83282 intact:EBI-1590491|ensemblbacteria:AAC65657 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595008|imex:IM-9152-2451 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:7CD07A38A916686C|rigid:wdezTVEGavNSfDnHD8lUJHe2+us false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:P96129 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590491|ensemblbacteria:AAC65657 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y688_trepa(display_long)|uniprotkb:TP_0688(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595014|imex:IM-9152-2452 author score:0.001673272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR040449|interpro:IPR003507(Peptidase S66, LD-carboxypeptidase A)|ensemblbacteria:AAC65657(transcript)|ensemblbacteria:TP_0688(gene)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|interpro:IPR027461|interpro:IPR027478|refseq:WP_010882133.1|interpro:IPR029062|interpro:IPR040921 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0688; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:6VVqXpJFu4SCZVn1l2ZtCSic1hU243276 intact-crc:8BB488BD6469D47C|rigid:xoCTpGXXBXIp/UlK5+TXESbECvg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83395 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595020|imex:IM-9152-2453 author score:0.626953387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0380|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:B313C309AD5FD4BD|rigid:VR2BOaW2I0ZVXCzV5mALo1vc6JE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83105 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595026|imex:IM-9152-2454 author score:0.588467562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:E862E9D457FC5067|rigid:n7wFDvuqC4I7SQD4TfsE7AK8fqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:P45685 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595038|imex:IM-9152-2456 author score:0.542193571 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:D18C9F02136A7ACA|rigid:y655lM/mAQCN+HbXiIVc8C2zT70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83195 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595032|imex:IM-9152-2455 author score:0.562162731 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:6B331CB46ED28B85|rigid:a34aA9PidIQmwqkhTKcXFQ0L8lI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83877 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595050|imex:IM-9152-2458 author score:0.209410925 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:FCB66933D8A3593D|rigid:8eqL3uYfZmlDJmAkW1cl0KoKlt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83804 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595044|imex:IM-9152-2457 author score:0.415238646 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:031202F9C1991C32|rigid:585Zk8giNUHO3j/2g0/BLp9eTVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83312 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595056|imex:IM-9152-2459 author score:0.194779272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:784E0D9B45C2B3DB|rigid:XEyTnDmZzzIwW9sbtin7RiHn9xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:P21992 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595062|imex:IM-9152-2460 author score:0.186472735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:EE1ABDB5A8C75CFF|rigid:Ucrf3ABhhw9syOzk9TU0/HRndkA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83587 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595068|imex:IM-9152-2461 author score:0.166907239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 intact-crc:0C266B0CDF25D3A8|rigid:B1Gda5rFQWFr31oOM/DQ1ph6SEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83574 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595074|imex:IM-9152-2462 author score:0.135871832 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C2C299BFC3A98BA2|rigid:WHPiG9p956yLh241tIeJl0bBhIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83587 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595080|imex:IM-9152-2463 author score:0.052154273 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 intact-crc:3B7209B4D3CA111B|rigid:43PnQq2CU8XONPlHtt2ORTPZMJo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83587 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595086|imex:IM-9152-2464 author score:0.043586496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 intact-crc:DE926BEA3A235EAE|rigid:KoEgZ138SIStgbgeVchEd/NAOsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83282 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595092|imex:IM-9152-2465 author score:0.017919089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9098721B978FFF14|rigid:1nJCFehpFehB0xsJnphscVYgIVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83954 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595098|imex:IM-9152-2466 author score:0.014887052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:C0B304E380D6C233|rigid:8QmjdA81LMJdk/i1RvcZvP71qUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83587 uniprotkb:O83958 intact:EBI-1586844|ensemblbacteria:AAC65553|ensemblbacteria:AGN75764 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83587_trepa(display_long)|uniprotkb:TP_0578(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595104|imex:IM-9152-2467 author score:0.000893809 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004390(Cell division transporter substrate-binding protein FtsY)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|ensemblbacteria:AAC65553(transcript)|ensemblbacteria:AGN75764(transcript)|ensemblbacteria:TP_0578(gene)|ensemblbacteria:TPANIC_0578(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|refseq:WP_010882024.1|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0578; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8oRmvhSZdlRy3zvbfeVLcyYuUZ4243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1EF9BCC51FA5E7CB|rigid:ywpalJSSdx/loYmyveX9UYq3Klo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83118 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595110|imex:IM-9152-2468 author score:0.626607228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 intact-crc:D62089E2C2940AD9|rigid:I1MI4YBJryug61DJ28cQEJ2YXAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83118 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595119|imex:IM-9152-2469 author score:0.166916726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 intact-crc:AF3727C40E63C128|rigid:oQkigZ/yD5hmXxDa9bUdaPEH7ME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83118 uniprotkb:O83282 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595137|imex:IM-9152-2472 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:B295AF689B0DBF4E|rigid:GQocUTGktbhm6qV+i638KX0I47M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83118 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595131|imex:IM-9152-2471 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 intact-crc:3D088360B6DE8F85|rigid:3R6B0GpUWvEEjbYBKw+oiHADdXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83118 uniprotkb:O83767 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595125|imex:IM-9152-2470 author score:0.088177508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:97C8B21784D92C69|rigid:nQRS3dN9+SMCFb0ThaCKHH3my/o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83118 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1595114|ensemblbacteria:AAC65074|ensemblbacteria:AGN75298 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83118_trepa(display_long)|uniprotkb:TP_0079(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595143|imex:IM-9152-2473 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|refseq:WP_010881528.1|ensemblbacteria:AAC65074(transcript)|ensemblbacteria:AGN75298(transcript)|ensemblbacteria:TP_0079(gene)|ensemblbacteria:TPANIC_0079(gene)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR036856|interpro:IPR037165 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0079; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:LIaJL0g5hdG9tLAIYlSH852i0qc243276 intact-crc:5A73CAB5CAA3FEC6|rigid:C2rjf3XNuIwXEWDUQZqHog7iUhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83262 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595155|imex:IM-9152-2475 author score:0.576972177 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:27F347DAC35A7719|rigid:Te9lDtL+Ri6IfwTJUmAzcRnesjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O66106 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595149|imex:IM-9152-2474 author score:0.624990831 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:090DED4265A0FD27|rigid:New2MOwhhMS4YCYSWDS+DMKDjc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83262 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595161|imex:IM-9152-2476 author score:0.446195506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:C159EFFBE0486D54|rigid:fJhyyWZ2JzrotdLRabgGlHOCNyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83939 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595167|imex:IM-9152-2477 author score:0.446195506 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:795192C601B6971D|rigid:BbgV0kO7RwNohsyB7SWihj64QPo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83532 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595179|imex:IM-9152-2479 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:4B02325936B42F8F|rigid:WUh5snHz9Va4OaZRfcbfuqIFFYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83262 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595173|imex:IM-9152-2478 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:8CA6E5691E5C4CAC|rigid:nubYDzYdsv5M9ghab3HKCUATzCw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83670 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595191|imex:IM-9152-2481 author score:0.374677525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:844AEA3C9C3B0D9F|rigid:f/pimEmJs8uFrbD0/kywa3SzgGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83565 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595185|imex:IM-9152-2480 author score:0.381006278 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:8F25C6B173F235A3|rigid:PJekjDrYFvXVFob+EKbcGWgvCHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83969 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595209|imex:IM-9152-2484 author score:0.212007964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:42367AADFDDAB24E|rigid:lv91QHf5UvBJfM6DmpiXLfJS7lo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83709 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595197|imex:IM-9152-2482 author score:0.302531602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:9F1CFE06A816742E|rigid:nsjkVAymJHt2NYcxJzWqqT/AOg0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83982 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595203|imex:IM-9152-2483 author score:0.266313147 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:905F42F49BA6D2B9|rigid:sz/0pr7orcMltWpW1+vLc4ulaQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83531 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595221|imex:IM-9152-2486 author score:0.185214407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:BEEAFFB068F1AB76|rigid:jclusvi365tNRTC+7w4OMXjL2Fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83262 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595215|imex:IM-9152-2485 author score:0.210838919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:4C5B6B7AF090E630|rigid:x75pse/xI7sR+ibv81g08VVDRf8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83413 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595227|imex:IM-9152-2487 author score:0.06500969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:3FFFF5B52BDE73C6|rigid:8bWqfvCrdG7kkmiPQb0IivJP4Qw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83667 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595233|imex:IM-9152-2488 author score:0.060269483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:9F8C245FE4632D16|rigid:cpbgjpnEWp4ieWHCSkve9HCTkJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83767 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595239|imex:IM-9152-2489 author score:0.04106747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:440947E1A3FCB400|rigid:Rq5RP/J322Kd4ADZmJMaLKI67e0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83745 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595245|imex:IM-9152-2490 author score:0.034255184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:DA7B673C40F6E6E2|rigid:YByV4aPWhuaN5gU1imzUJnRyDZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83262 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1586738|ensemblbacteria:AAC65222 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595251|imex:IM-9152-2491 author score:0.01400239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 intact-crc:3C6E71F7DE0C1450|rigid:dRdZX53wgb8ak3+fnrOAr+6XtD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83262 uniprotkb:O83958 intact:EBI-1586738|ensemblbacteria:AAC65222 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rl33_trepa(display_long)|uniprotkb:rpmG(gene name)|psi-mi:rpmG(display_short)|uniprotkb:TP_0234(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595257|imex:IM-9152-2492 author score:0.000695806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001705(Ribosomal protein L33)|interpro:IPR018264|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65222(transcript)|ensemblbacteria:TP_0234(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR038584|refseq:WP_010881682.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0234; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rhtTfHujP98pWC4o4Ojz8y/Y5Ic243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:03D84570502402E1|rigid:GyVAvoib/x7XRYu12GGSE4/B7EM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54312 uniprotkb:O83457 intact:EBI-1585555|ensemblbacteria:AAC65025 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:mura_trepa(display_long)|uniprotkb:murA(gene name)|psi-mi:murA(display_short)|uniprotkb:Enoylpyruvate transferase(gene name synonym)|uniprotkb:UDP-N-acetylglucosamine enolpyruvyl transferase(gene name synonym)|uniprotkb:TP_0029(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595263|imex:IM-9152-2493 author score:0.622823362 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001986(3-phosphoshikimate 1-carboxyvinyltransferase, core)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR005750(UDP-N-acetylglucosamine 1-carboxyvinyltransferase)|ensemblbacteria:AAC65025(transcript)|ensemblbacteria:TP_0029(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008760"(UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0019277"(UDP-N-acetylgalactosamine biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036968|refseq:WP_010881478.1 refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0029|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:d4PyWi87nR8fF05GyNfhlPPwVSs243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:0B7D51730E954AF8|rigid:9kGy8ruvgqQVHn3/1RiiaG2lo6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83457 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595275|imex:IM-9152-2495 author score:0.512538615 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:C9EF863BB34B915D|rigid:XdYi4VNGnfUrogDI3abvoo/3O7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83986 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595269|imex:IM-9152-2494 author score:0.544501835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:9881EAEC7FA67905|rigid:4epJGID0qzlnSIa3HJT8TLJVpzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83457 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595281|imex:IM-9152-2496 author score:0.504236091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:9285E961039C43C2|rigid:O9xRDS0MJApCqo0oZCNXPgtArJE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83275 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595287|imex:IM-9152-2497 author score:0.497505594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:657DA53DA9112851|rigid:sW/GArqluIP33GDKMNYdmGq0LGc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O66107 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595293|imex:IM-9152-2498 author score:0.490776001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:BD8E7252F0288194|rigid:iCiYojhGj/WIsgK9Q47NY0n15Ps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83752 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595299|imex:IM-9152-2499 author score:0.430649313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:77D20D7B13105177|rigid:2OIMtRsnyASyrC6Uc5ifb4TUk58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83970 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595305|imex:IM-9152-2500 author score:0.341612383 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:A249D84ABDB2F47B|rigid:maLnbejvrj/0fj+4Qma5j4no2Mg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83982 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595311|imex:IM-9152-2501 author score:0.227674498 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:E9B3B25D1358191D|rigid:Lt36ge6cvpPcF3BKs5vG5arYODI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83969 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595317|imex:IM-9152-2502 author score:0.187888124 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:500E260889B18C1A|rigid:ms/lVLRnWqWUPdNKE8HGBuSNY2c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83413 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595323|imex:IM-9152-2503 author score:0.110901453 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:0B2D2E7D9E65E1EC|rigid:2jZcK05lGtDrxQ8y+ge5HWkdku0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83457 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595329|imex:IM-9152-2504 author score:0.080690608 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:7094B1150F3D8F4E|rigid:j47QluPrZhPJOIqpw0pV/pAK5e4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83667 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595335|imex:IM-9152-2505 author score:0.067770131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:8AE76BDA21765E46|rigid:zlTlwuUxreWSQMLeoFhX1P3VnyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83457 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595341|imex:IM-9152-2506 author score:0.046296122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:D2F44CA51C6F2658|rigid:8u+yWZdVkvl6iMWutY3KKszN+J8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83457 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595347|imex:IM-9152-2507 author score:0.015842082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:ADE4D607E3FF8C04|rigid:Q63ajLmLeHrIwqxKDp17mj5BDXw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83954 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595353|imex:IM-9152-2508 author score:0.013156781 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:06E71F9C99DEBE4F|rigid:ZgAfz8eTOe+xe/+RGxEV3FwLOzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83958 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595359|imex:IM-9152-2509 author score:0.000788623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0443; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:FC0BB825251D4B5D|rigid:rTfUkuj+LfoLrxmPXq8yIAWk0Ug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83261 uniprotkb:O83902 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595365|imex:IM-9152-2510 author score:0.620519326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:8738849B016BD0DF|rigid:HVyGWvcYyYPALGvALJ4yGKTN/s0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83902 uniprotkb:O83977 intact:EBI-1595369|ensemblbacteria:AAC65890 intact:EBI-1583534|ensemblbacteria:AAC65964 psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595374|imex:IM-9152-2511 author score:0.614159502 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 intact-crc:68E7DA1F445ADCFB|rigid:bVBsAaN3sDchtawKzmNQmy1aPAg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83902 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595380|imex:IM-9152-2512 author score:0.292909869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:B8AA8F07B9018E1A|rigid:dSnOiQ1BQ/4jjdU7p/P69P6gvfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83902 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595386|imex:IM-9152-2513 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:13E507109BB80DED|rigid:gSXQyRCOrLVeiyrPbGE+CSUIDyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83902 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595392|imex:IM-9152-2514 author score:0.225956533 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:BCB563029B4FA8DC|rigid:SPj3Y5gkOAqD5HE23J562zP1CW0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83902 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595398|imex:IM-9152-2515 author score:0.194701921 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:5279A4435D6050A8|rigid:Y9IzAgGxUJB/zBv1VnF11KrHDKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83902 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595404|imex:IM-9152-2516 author score:0.159487671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:54E5CFEB47F82124|rigid:dSpy65l/NOMSJ4tfKF4DjrqhXpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83902 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595422|imex:IM-9152-2519 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:13B1DDDEC6064642|rigid:BKsOu+AUwpwnXYr0AlxDnCwgH68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83902 uniprotkb:O83877 intact:EBI-1595369|ensemblbacteria:AAC65890 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595410|imex:IM-9152-2517 author score:0.107194186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:46027E513A0D2BF4|rigid:kkvuVm2/hbfLvCyvH0V8eVKttFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83902 uniprotkb:O83767 intact:EBI-1595369|ensemblbacteria:AAC65890 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595416|imex:IM-9152-2518 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:EECC1EA1735D83EF|rigid:jS8IHMMb81lPTinP3FiHUrF5l40 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83902 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1595369|ensemblbacteria:AAC65890 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595428|imex:IM-9152-2520 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 intact-crc:21436CD08D7F72C0|rigid:PH+9fedYsq8s4pe7MMlBlUjBLu0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83902 uniprotkb:O83958 intact:EBI-1595369|ensemblbacteria:AAC65890 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595434|imex:IM-9152-2521 author score:0.00107844 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0932; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7BE1F61B9E76E391|rigid:K4iPsSyTlLNGK5k+aVHyyogGjrg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83752 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595444|imex:IM-9152-2522 author score:0.616414601 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:2D1DEDB7C858302E|rigid:ITi3Ib7DdOBbByV8EIoFwnV8JGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83670 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595462|imex:IM-9152-2525 author score:0.465984223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:6A1613B8F1D6B11F|rigid:UiEENQOBoTReSy58RlxdbJNnNkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83570 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595450|imex:IM-9152-2523 author score:0.598485753 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:E7497E8368A69B9E|rigid:3/m4GOasl7pb02iGDRHzBEz34G8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83265 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1595440|ensemblbacteria:AAC65225 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595456|imex:IM-9152-2524 author score:0.492854561 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 intact-crc:34B31B9B1E039E44|rigid:oaUJSnMXyudrPfWU22Vc4QfijKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83265 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1595440|ensemblbacteria:AAC65225 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595468|imex:IM-9152-2526 author score:0.387141619 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 intact-crc:058F4663D0321F45|rigid:Yf62RtnBjrKVN89H9q2VhP/SFgI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83531 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595474|imex:IM-9152-2527 author score:0.248714004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:D593D8BFB3D61420|rigid:7XefZpkLIHf5R3wo2Fr1PmsavEI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83312 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595480|imex:IM-9152-2528 author score:0.215186659 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:3F2820C9E9EF81BC|rigid:TyLG1dZa71zDdX5kuqLl+blUxJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83265 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1595440|ensemblbacteria:AAC65225 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595486|imex:IM-9152-2529 author score:0.091948564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 intact-crc:04E88B221B40D359|rigid:FAsY1krrWHEhzXJPdMo2mVwF4iY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83667 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595492|imex:IM-9152-2530 author score:0.08542356 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B542415FB0DE12AE|rigid:QDhBUPV7qkUmhMQpCNAi6yR2ddU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83767 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595498|imex:IM-9152-2531 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E0587D51C245F2A0|rigid:htpTGg2IkPtUAjTXouMWYz32hTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83265 uniprotkb:O83745 intact:EBI-1595440|ensemblbacteria:AAC65225 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595504|imex:IM-9152-2532 author score:0.04911944 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:C15A489FAA9DA4F2|rigid:VoFRf2ng1pY/xBA/LUsErYhiw9I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83265 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1595440|ensemblbacteria:AAC65225 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595510|imex:IM-9152-2533 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 intact-crc:0097819D1344AA6A|rigid:xBZpJOh2NHyXkdFmHMO2PXef8Xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83265 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1595440|ensemblbacteria:AAC65225 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rl11_trepa(display_long)|uniprotkb:rplK(gene name)|psi-mi:rplK(display_short)|uniprotkb:TP_0237(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595516|imex:IM-9152-2534 author score:0.001013011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020785|interpro:IPR020784|ensemblbacteria:AAC65225(transcript)|ensemblbacteria:TP_0237(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|refseq:WP_010881685.1|interpro:IPR036769|interpro:IPR036796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0237; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:T5+xAvjFhsu9ubNqA/CS99vmWsg243276 intact-crc:9250BB0B5A15D734|rigid:mJ597RjVzjhpgxoggjQTs4crkfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83425 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1595522|ensemblbacteria:AAC65398 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595526|imex:IM-9152-2535 author score:0.61603482 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 intact-crc:E8C9A358DBCD4E37|rigid:RRosATosri3RuC2xi60CPdCE4l4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83425 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1595522|ensemblbacteria:AAC65398 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595532|imex:IM-9152-2536 author score:0.60120594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 intact-crc:B2F60A8906D51E17|rigid:gel6oaFIzqoFYUQcWeg5lKaY/Wk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83425 uniprotkb:O83311 intact:EBI-1595522|ensemblbacteria:AAC65398 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595538|imex:IM-9152-2537 author score:0.575127466 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:E3FA8C80C8BE410C|rigid:wU7j4wdPnZlUtcgm8y8LjlBlRIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83425 uniprotkb:O83305 intact:EBI-1595522|ensemblbacteria:AAC65398 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595544|imex:IM-9152-2538 author score:0.333292903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:6150394DD294F4F2|rigid:yHHVHB+JufYHr4K1drNBedTAs6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83425 uniprotkb:O83398 intact:EBI-1595522|ensemblbacteria:AAC65398 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595550|imex:IM-9152-2539 author score:0.327337582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:A42982FADBA486E6|rigid:CKPxFgbvIHtTXsC6cso1Hoa4Rlg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83425 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1595522|ensemblbacteria:AAC65398 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595556|imex:IM-9152-2540 author score:0.298413524 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 intact-crc:C82AEC20D56A6011|rigid:q7ychPelpsZZ7E0AZudEuAi26eU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83425 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1595522|ensemblbacteria:AAC65398 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595574|imex:IM-9152-2543 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 intact-crc:9CF64284219EE6AA|rigid:gD219iv4p0i5cQ+qaa6mxcDucaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83425 uniprotkb:O83667 intact:EBI-1595522|ensemblbacteria:AAC65398 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595562|imex:IM-9152-2541 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:EA0C12A05BE4F5DA|rigid:/wJa/b3rksFs0F7LN66tvqP6GkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83425 uniprotkb:O83767 intact:EBI-1595522|ensemblbacteria:AAC65398 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:secd_trepa(display_long)|uniprotkb:secD(gene name)|psi-mi:secD(display_short)|uniprotkb:TP_0410(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595568|imex:IM-9152-2542 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005791(SecD export membrane protein)|interpro:IPR022813|interpro:IPR022645|ensemblbacteria:AAC65398(transcript)|ensemblbacteria:TP_0410(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881858.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0410; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hF+LtaJGXG+sQUIRRAn7eOR1Arw243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:5683E260AC6D7150|rigid:jZJRZN7/Hu8B7F+hjrYa1LqlmP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83092 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1198878|intact:EBI-1588541|ensemblbacteria:AAC65049 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:rir2_trepa(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:TP_0053(locus name)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595580|imex:IM-9152-2544 author score:0.615895006 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|refseq:WP_010881502.1|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)|ensemblbacteria:AAC65049(transcript)|ensemblbacteria:TP_0053(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0053; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:z67SeoH9YUD2zHKtcxYMO/oOe9M243276 intact-crc:93A9BCA1976CE5DC|rigid:CZ2wD8uqgTx6HAP/aJuj0u3r+v8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83092 uniprotkb:O83927 intact:EBI-1198878|intact:EBI-1588541|ensemblbacteria:AAC65049 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rir2_trepa(display_long)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:TP_0053(locus name)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595586|imex:IM-9152-2545 author score:0.31148288 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR030475|refseq:WP_010881502.1|interpro:IPR033909|interpro:IPR012348(Ribonucleotide reductase-related)|ensemblbacteria:AAC65049(transcript)|ensemblbacteria:TP_0053(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046872"(metal ion binding) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0053; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z67SeoH9YUD2zHKtcxYMO/oOe9M243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:26A4113825BAFB02|rigid:fOHBMWJLMjE26TMphF7qzXUdYBA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83426 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1595596|ensemblbacteria:AAC65399 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:secf_trepa(display_long)|uniprotkb:secF(gene name)|psi-mi:secF(display_short)|uniprotkb:TP_0411(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595592|imex:IM-9152-2546 author score:0.609301798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR022813|interpro:IPR022645|interpro:IPR005665(SecF protein)|ensemblbacteria:AAC65399(transcript)|ensemblbacteria:TP_0411(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881859.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0411; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:f2tWET9wWWP3fbJBsinaxBJLhFw243276 intact-crc:96B2AF0D97B9A7E2|rigid:eCRRVZgYMJWo9zDx/Dkh5HhAhoo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83426 uniprotkb:O83572 intact:EBI-1595596|ensemblbacteria:AAC65399 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:secf_trepa(display_long)|uniprotkb:secF(gene name)|psi-mi:secF(display_short)|uniprotkb:TP_0411(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595602|imex:IM-9152-2547 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022813|interpro:IPR022645|interpro:IPR005665(SecF protein)|ensemblbacteria:AAC65399(transcript)|ensemblbacteria:TP_0411(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881859.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0411; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f2tWET9wWWP3fbJBsinaxBJLhFw243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:414118228530E19F|rigid:1VieZv6ly9C4k79bSzeTCRSE6o8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83191 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1595608|ensemblbacteria:AAC65146|ensemblbacteria:AGN75375 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:o83191_trepa(display_long)|uniprotkb:TP_0156(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595611|imex:IM-9152-2548 author score:0.607995616 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR006684(4-hydroxybenzoyl-CoA thioesterase)|interpro:IPR006683(Thioesterase superfamily)|ensemblbacteria:AAC65146(transcript)|ensemblbacteria:AGN75375(transcript)|ensemblbacteria:TP_0156(gene)|ensemblbacteria:TPANIC_0156(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881603.1|interpro:IPR029069 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0156|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:hLcPNDzxtINfYUerE/QNCqEBJoA243276 intact-crc:245845818ED66C19|rigid:Kiokzvc98XCp0rs6x2iKbu1Z094 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83657 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595617|imex:IM-9152-2549 author score:0.528923905 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:204C389F0100FE3E|rigid:RXn0WNrwHBbWHlO3T25+b2IgXAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83595 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595623|imex:IM-9152-2550 author score:0.508763479 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:7ABC615A9FD12DE7|rigid:9lKgUgAYqTbVzost2m8el9wu+34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83412 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595629|imex:IM-9152-2551 author score:0.448373455 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:1F86F5CA71DBA7E6|rigid:2h3NPtVAnouHU8ZgfHiIc6ciKKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83970 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595635|imex:IM-9152-2552 author score:0.327663494 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:A8C04F358AA4ED74|rigid:ri7oz+mBVXY6hVLA9ROcYr3tIO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83463 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595641|imex:IM-9152-2553 author score:0.287567173 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:1AD0CAD2F4A2C22A|rigid:GwEq7rxYQg0IPCuUIe18TBKs2v4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83398 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595647|imex:IM-9152-2554 author score:0.21684568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:A1B70ACE98C850AD|rigid:n6uzpR/Mssce/Pbn+k3TdLGWiLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83969 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595665|imex:IM-9152-2557 author score:0.178514259 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:529F2D9C27A95A83|rigid:l4HIMwwSDZjNiZU14V5yW4xHnoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83099 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595653|imex:IM-9152-2555 author score:0.215968529 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:801FB1E5F0D9EDCF|rigid:ViLCJvTk4vWKlkiZZwBbn8UeP70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83531 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595659|imex:IM-9152-2556 author score:0.194856647 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:47C471A90C565789|rigid:MHGwId8iuIOujuE23eeb+xpEGI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83657 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595671|imex:IM-9152-125 author score:0.15961996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:A8231E6069D3AEB7|rigid:wvupCt5L4gFa4O3N5SHv0EKtL/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83657 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595677|imex:IM-9152-126 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:0106DC30EEB137A1|rigid:2uOcrd2a4QgIG3TFcBvMq5dua2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83877 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595683|imex:IM-9152-127 author score:0.076163326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:D3370F99CD934A43|rigid:QdCguhHZztkx+mCjKQLiMIiZ8v0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83413 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595689|imex:IM-9152-128 author score:0.068923443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:AE6761ADC3B129B4|rigid:8IPwateo/ig2VhP7bqiyajgYOZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83767 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595695|imex:IM-9152-129 author score:0.043607063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E381A126A0BA8611|rigid:4xQCnX7/SuH+nlVco3FED/or310 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83657 uniprotkb:O83282 intact:EBI-1584057|ensemblbacteria:AAC65624 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595701|imex:IM-9152-130 author score:0.014894287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:88FA845CD9693146|rigid:I8pvUyv7XVEeRPIX+AkpKEDXPtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83657 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595707|imex:IM-9152-131 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:C86E7651E5AD2BE0|rigid:GsZ8iFccG+PpkUSG7LiBX4IAhc8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83657 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584057|ensemblbacteria:AAC65624 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83657_trepa(display_long)|uniprotkb:TP_0651(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595713|imex:IM-9152-132 author score:0.000740763 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011624(Metal-dependent phosphohydrolase, 7TM extracellular region)|interpro:IPR011621(Metal-dependent phosphohydrolase, 7TM intracellular region)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR006675(HDIG)|ensemblbacteria:AAC65624(transcript)|ensemblbacteria:TP_0651(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882096.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0651; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:HEu0bG/vxAeZ7Tekt9Xzu2WvLaM243276 intact-crc:26646F8B7FF7F7F7|rigid:tTlOoxtpikFvXhTxiuHHbyoredI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83227 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595722|imex:IM-9152-133 author score:0.607760467 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:FA14111F9268519B|rigid:PX6Y9DQrJkgfVcGfHLIWCXaWbKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83531 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595728|imex:IM-9152-134 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:BC4F75B9B4FFDFC6|rigid:CQ8zNGisoP+Mq4tZAc/ZycF12sk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83969 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595734|imex:IM-9152-135 author score:0.240394489 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:7E71730440161F6E|rigid:lxlz4RqS8PS/NrHpyn5wu35RD2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83193 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595740|imex:IM-9152-136 author score:0.221282554 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:C1B8A9C211BEA89B|rigid:CbWgf8SMZmnDHBel8SkxoxlSNZA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83193 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595746|imex:IM-9152-137 author score:0.194701921 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:2377849B821C8B27|rigid:IJRVoAR20MgHZknU65KwKEw6jrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83574 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595752|imex:IM-9152-138 author score:0.159487671 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:9758A10FB9205ABC|rigid:lljSbXaxbmTLn4Zp2TrYcHiGksk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83193 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595764|imex:IM-9152-140 author score:0.090447395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:9E431956A9F9AF0D|rigid:Ei4PhbLkyopS8eUsbb2zg+ZrbD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83193 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595758|imex:IM-9152-139 author score:0.107194186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:0845F7D9C415FE9F|rigid:YTlbxVMkr4wrR9cuZNZK3XwopcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83193 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595776|imex:IM-9152-142 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:E0EAAFFEF1F03FB4|rigid:dyqbTsxvmSzydOteGtz8TXRAgEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83767 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595770|imex:IM-9152-141 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:BCF4214E67DBE6D3|rigid:uNo+eTsINmrzIctF8W7GibvrwdI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83193 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595782|imex:IM-9152-143 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 intact-crc:EC061985F7A6F19A|rigid:7mHobQDy52fro7rUD+LPXAj7Vmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83193 uniprotkb:O83958 intact:EBI-1595719|ensemblbacteria:AAC65148|ensemblbacteria:AGN75377 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83193_trepa(display_long)|uniprotkb:TP_0158(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595788|imex:IM-9152-144 author score:0.00107844 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|ensemblbacteria:AAC65148(transcript)|ensemblbacteria:AGN75377(transcript)|ensemblbacteria:TP_0158(gene)|ensemblbacteria:TPANIC_0158(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881605.1|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR010237(Pyrimidine 5-nucleotidase)|interpro:IPR036412 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0158; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gdCCJPQ6QkvNtbZPdbYDmfoDbSg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B6A4834EE4AF60CB|rigid:hLe152eqxSDRU/AUecwVhDJmNzc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83481 uniprotkb:O83738 intact:EBI-1595794|ensemblbacteria:AAC65449 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83481_trepa(display_long)|uniprotkb:TP_0468(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595797|imex:IM-9152-145 author score:0.60740765 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65449(transcript)|ensemblbacteria:TP_0468(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0468; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uc7oQrslh2/02U579WTZJ/KOegk243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:9EE517866242D6E9|rigid:3VR1UCNc2PuMkLtnf6k4fjPQO1c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83481 uniprotkb:O83982 intact:EBI-1595794|ensemblbacteria:AAC65449 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83481_trepa(display_long)|uniprotkb:TP_0468(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595803|imex:IM-9152-146 author score:0.414759643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65449(transcript)|ensemblbacteria:TP_0468(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0468; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uc7oQrslh2/02U579WTZJ/KOegk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:C5A6D9627EE7E496|rigid:UfSVTSo74LTh99j/j4hMIH0Mg9k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83481 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1595794|ensemblbacteria:AAC65449 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83481_trepa(display_long)|uniprotkb:TP_0468(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595809|imex:IM-9152-147 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65449(transcript)|ensemblbacteria:TP_0468(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0468; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:uc7oQrslh2/02U579WTZJ/KOegk243276 intact-crc:0C5CB6AD474217C7|rigid:viSPrAvRSvDrt2xsiR3lOEhcQkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83909 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595815|imex:IM-9152-148 author score:0.605397601 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:90B25150EBC44117|rigid:+H/Z6dxb0MUtbxOgCJkXivK6MXw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83909 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595821|imex:IM-9152-149 author score:0.515490037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:A115CA3BC9045FF1|rigid:oyaiV5ky4cQ6NVekdeE+ECbMwYg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83738 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595827|imex:IM-9152-150 author score:0.376743865 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:B9B9A864A239EBDA|rigid:CUaRrE7cxlc745/uY6y5BPZ3j7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83969 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595839|imex:IM-9152-152 author score:0.272198216 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:49AECB797B34255E|rigid:9265rxpuzKNUHuQ7UL84izAbjPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83909 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595833|imex:IM-9152-151 author score:0.287567173 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:8BE46782092EC88E|rigid:cLVHQCZ68RbfX3lV38RUiLwLQOc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83909 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595845|imex:IM-9152-153 author score:0.221452594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:8A8CB07CA020493F|rigid:nGwiCixe+gkboqFJUgYSi8a+58I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83982 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595851|imex:IM-9152-154 author score:0.21684568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:083D82956A94CF4D|rigid:IIA/cQQlA9avSbyUI7OuNABF4xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83909 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595857|imex:IM-9152-155 author score:0.213399063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:86A4A521F1C89538|rigid:qel3VX5aHpDNN6xA31tW9jReCRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83531 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595863|imex:IM-9152-156 author score:0.194856647 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:D6F0DCF9F1DA5D2D|rigid:ia94zMznWWJixTPMv/6HwIRZ+Mw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83909 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595869|imex:IM-9152-157 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:043E6BB60033356C|rigid:2g7Y0gej1RwgV0S7CeMzmx5dmAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83927 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595875|imex:IM-9152-158 author score:0.142378866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:5C6C76C0A5779C8B|rigid:qe8OZZ3r3ceezJjOEleVROmky3I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83877 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595887|imex:IM-9152-160 author score:0.076163326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:5E72751C0E8F75A5|rigid:k/Tp5u8nvLU5bsUP/PXkYUE047A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83574 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595881|imex:IM-9152-159 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:11BE255564BC9D56|rigid:H0eQDvzocFOYTquznBodh+eAYWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83909 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595899|imex:IM-9152-162 author score:0.058354843 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:050DA7126151725D|rigid:cEQwPolD8nY4Bd8KEXlERxr2k28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83909 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595893|imex:IM-9152-161 author score:0.068923443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 intact-crc:3F53CCFD3E3D2310|rigid:A5fMrWnqJVen341x8FZdzfRl6dU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83954 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595911|imex:IM-9152-164 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:955F6DD46398D468|rigid:mMcbit/YWmBdLFfdfl5uaKxsM0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83958 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595917|imex:IM-9152-165 author score:0.000740763 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7B55740EF9C2087F|rigid:dOUKBJ0MioXLNby/5cAcUvTcZVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83282 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595905|imex:IM-9152-163 author score:0.014894287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0939; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:19CE290C24E53BE2|rigid:pRqQySOnSXXzSM8i7NtRdeJdcXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83107 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1585371|ensemblbacteria:AAC65061 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595923|imex:IM-9152-166 author score:0.60435058 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 intact-crc:FCBD8FE49ECBC9D7|rigid:AuOWDv4jHS58e/ZY2T5uZHitVDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83107 uniprotkb:O83969 intact:EBI-1585371|ensemblbacteria:AAC65061 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595929|imex:IM-9152-167 author score:0.424106037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:6D05BEED7785831A|rigid:pgKQUmOd9r6OX7Mdbvc+4cOiaFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83107 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1585371|ensemblbacteria:AAC65061 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595935|imex:IM-9152-168 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 intact-crc:323839C97832CB62|rigid:efJze7P5AMxIGzc5gJj9sibO7dU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83107 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1585371|ensemblbacteria:AAC65061 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595941|imex:IM-9152-169 author score:0.093055067 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 intact-crc:46DC8835D996BED3|rigid:/RlohsSabhdFFIhLcP+I36FxyFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83107 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1585371|ensemblbacteria:AAC65061 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595947|imex:IM-9152-170 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 intact-crc:51E21259A910B191|rigid:g7b1TlaUzKtOy22nqoR5oJftsEg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83107 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1585371|ensemblbacteria:AAC65061 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595953|imex:IM-9152-171 author score:0.002148373 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0068; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 intact-crc:2E3B5887BE8D4B02|rigid:fz/UYphyo04zmInsENDa927QqOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83463 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595965|imex:IM-9152-173 author score:0.430286523 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:4F187B3404D22034|rigid:SZilC3S31TXACtGU06MjV+tLaL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83595 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595959|imex:IM-9152-172 author score:0.603316244 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:49F2BDCFBD54B59B|rigid:tRuP8B4YZc73Yz09hRlooYCPm08 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83595 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595977|imex:IM-9152-175 author score:0.347357628 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:FE7D0879F5DDC607|rigid:p1d7200GQfBIaQL28auFBqui08o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83099 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595971|imex:IM-9152-174 author score:0.35523835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:0F72DD841ED7C1A3|rigid:gRIEVvy8fGBcu4ohvahN6QmM4aU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83595 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595983|imex:IM-9152-176 author score:0.262210377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:0AB1393B7A61B2DF|rigid:TKzGYRAIb6QdTt7qJmU8izfix18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83877 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595989|imex:IM-9152-177 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:CD63463F1BF8B273|rigid:v2DjM9xNU/GgI0bH/D9x9YZfJSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83595 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596001|imex:IM-9152-179 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:1F83F84AFC34407C|rigid:nIkk9uw2Q4JcPpZXSyHMLAHwjv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83282 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1595995|imex:IM-9152-178 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0586; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:ACED3B5D192700F9|rigid:nYrpHLrVj69iSWvXZEfv1EnH+aE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83637 uniprotkb:P29722 intact:EBI-1198342|intact:EBI-1582991|ensemblbacteria:AAC65612 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:y629_trepa(display_long)|uniprotkb:TP_0629(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596017|imex:IM-9152-181 author score:0.575489017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65612(transcript)|ensemblbacteria:TP_0629(gene) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0629|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XN07TtykhiRKrwrGTR75f3xtRXk243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:710B88FCF285D6C9|rigid:cdVTFont9sqqZSfOizFfB4AIoao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83480 uniprotkb:P29722 intact:EBI-1198943|intact:EBI-1591730|ensemblbacteria:AAC65458 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:y467_trepa(display_long)|uniprotkb:TP_0467(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596011|imex:IM-9152-180 author score:0.601560674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65458(transcript)|ensemblbacteria:TP_0467(gene)|refseq:WP_010881916.1 rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0467|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nDrRjBq25heuBpAxyJmI6S5DhJM243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:F611A3DD5D6F8A1B|rigid:gav6o6JVtxhi8n/V1n5zOiQPSCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O07885 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596023|imex:IM-9152-182 author score:0.568898823 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 intact-crc:A7167883E5BE2994|rigid:5iqGR0kOBfVS3NzzFO522n8muAY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:P29722 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596029|imex:IM-9152-183 author score:0.562284136 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:2103B5C4E9000736|rigid:LTJCCPWS+Nj8yI9V5pTejfmXnKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83089 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596035|imex:IM-9152-184 author score:0.548990408 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0050|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:4FEDCA890FE1508E|rigid:DWbMxZTDkptEYBiYbXgdSkVqg4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:P45685 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1198212|intact:EBI-1581726|ensemblbacteria:AAC65042 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:tpl_trepa(display_long)|uniprotkb:tpl(gene name)|psi-mi:tpl(display_short)|uniprotkb:TP_0046(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596047|imex:IM-9152-186 author score:0.495303277 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR007557(PSP1 C-terminal conserved region)|refseq:WP_010881495.1|ensemblbacteria:AAC65042(transcript)|ensemblbacteria:TP_0046(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0046|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:2HhlfKIaE8nMy3JExH7pJ0L/rig243276 intact-crc:1EC4818ADF98C116|rigid:63DL4PEzCsu7c33MfLFEWi1CFvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:P29722 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596041|imex:IM-9152-185 author score:0.515490037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:7690B32204968E5B|rigid:AKZFphHTffw06xxIuNcip8Uuoac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:P29722 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596059|imex:IM-9152-188 author score:0.435095847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:EEA0F2E398994B6F|rigid:Pi/mJfNDWmFJRMYMH4IT1PpUpi4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83275 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596053|imex:IM-9152-187 author score:0.481849879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:E17CCF770C4A5F66|rigid:NB7vXSD3AQkT97BpBTj7/p+2BdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:P29722 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596065|imex:IM-9152-189 author score:0.376743865 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:6E3CD17D6FAB3A70|rigid:OCfTwXkIOqsarmBiIlilrQAfdkM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83312 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596077|imex:IM-9152-191 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:D3BB12AFCDA1E4C6|rigid:d0vlamjC4JKPf3IoCUo0bv8PST8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:P29722 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596071|imex:IM-9152-190 author score:0.370443541 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:019BFCAA304B6BD7|rigid:P4LrnqsCeKIPg+vIn95gvzpf78A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83574 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596083|imex:IM-9152-192 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C5773664F66C3BD0|rigid:WvyDUWjWeHCZBJvqubil7rAnMT4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83877 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596089|imex:IM-9152-193 author score:0.076163326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:89F70C05C31DA40F|rigid:hPUxDsfAL+R20JTkGaUcbig3VMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83767 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596101|imex:IM-9152-195 author score:0.043607063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:A53E14DD44AAD80A|rigid:z0YRfInCzTxxPeX07bdBwxXJd+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83282 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596107|imex:IM-9152-196 author score:0.014894287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:CE4B5015E977EA48|rigid:ejE73HqPM4MbmvYJIcVmOuxUPBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29722 uniprotkb:O83667 intact:EBI-1596007|ensemblbacteria:AAC65423 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596095|imex:IM-9152-194 author score:0.063917372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:A369247398B54EA0|rigid:pDa4T4UYwhLPNWnNp+3s6N1AAA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:P29722 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1596007|ensemblbacteria:AAC65423 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:ta17_trepa(display_long)|uniprotkb:tpp17(gene name)|psi-mi:tpp17(display_short)|uniprotkb:TP_0435(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596113|imex:IM-9152-197 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) rcsb pdb:4U3Q|interpro:IPR007298(Copper resistance lipoprotein NlpE)|ensemblbacteria:AAC65423(transcript)|ensemblbacteria:TP_0435(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881883.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0435; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:BhBnCzOX2SpVa1ybYlBls3jhkwc243276 intact-crc:2CCFE6EB3CBEF8D4|rigid:LNXfzjxDl3fRR9b4hSqs4z+2ZOM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:Q01305 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596123|imex:IM-9152-198 author score:0.599210334 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:95E57ED04ECE6713|rigid:7v/6UgDtMqyAMpbEhASSPs18Kew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01305 uniprotkb:O66106 intact:EBI-1596119|ensemblbacteria:AAC65002 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596129|imex:IM-9152-199 author score:0.566494659 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:EE65A25B6E4149A6|rigid:12z5FcnPQt09HMlIXRzQ02PYXjU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01305 uniprotkb:O66107 intact:EBI-1596119|ensemblbacteria:AAC65002 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596135|imex:IM-9152-200 author score:0.553227201 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:358D8FBA5584B59F|rigid:rfO0XhkEyYGTQNgrj+2lsYshgeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:Q01305 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596141|imex:IM-9152-201 author score:0.539883493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:321F7B01BBC85222|rigid:vG5qo+tYjxzMDHxYe1Qoqo5ZweA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:Q01305 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596153|imex:IM-9152-203 author score:0.465984223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:32A27A857B77BC30|rigid:s/X7k1XRJsg3520AnGqb2RgV+us false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01305 uniprotkb:O83627 intact:EBI-1596119|ensemblbacteria:AAC65002 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596147|imex:IM-9152-202 author score:0.533188916 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:E39E8BC73EFD2010|rigid:U6XtyqVHz/s8c9ZnfiqXJFPxxPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:Q01305 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596159|imex:IM-9152-204 author score:0.280103578 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:C7B7D489B5BC8E16|rigid:rcffIbZhlJe9Ary/91saX1nv97U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:Q01305 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596165|imex:IM-9152-205 author score:0.248714004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:DD78E9601A7310E4|rigid:LphtpTI50MnY+XYpju8TJJWZpdI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:Q01305 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596171|imex:IM-9152-206 author score:0.151266804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:28FBD4ED5CF4C5A8|rigid:grijC1HY8K+Hij0NK2PO9MLSk6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:Q01305 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596177|imex:IM-9152-207 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:4671D56774D46331|rigid:63uecGGnfdcAO6UsdxO3YzfJ+Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:Q01305 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1596119|ensemblbacteria:AAC65002 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596183|imex:IM-9152-208 author score:0.04911944 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 intact-crc:66168435FA98EAEE|rigid:xKhygRYIINoxeWhPyTO9n15cZC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01305 uniprotkb:O83954 intact:EBI-1596119|ensemblbacteria:AAC65002 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596189|imex:IM-9152-209 author score:0.016840989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:13FF3C7D2F2F8482|rigid:fCRsQ+mJIF/sZmIxO3cnnsBlBWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83910 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596201|imex:IM-9152-211 author score:0.599210334 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:9D6E8AAA01D75227|rigid:fdOmjbbHS1PPdz8o4JJyyCZMgds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01305 uniprotkb:O83958 intact:EBI-1596119|ensemblbacteria:AAC65002 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:tp75_trepa(display_long)|uniprotkb:Tp75(gene name)|psi-mi:Tp75(display_short)|uniprotkb:TP_0006(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596195|imex:IM-9152-210 author score:0.001013011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65002(transcript)|ensemblbacteria:TP_0006(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0006; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wH5cCB+jTeuGD72TD9gOi9he1+I243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:0D64813C9D4478F5|rigid:zGrrKJKo8lXknlzwb+F2HGEwSvU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83910 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596210|imex:IM-9152-212 author score:0.533188916 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:2D80219659E1B21E|rigid:dd2By+LFh8zYXe5ENLy42zm761w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83805 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596216|imex:IM-9152-213 author score:0.465984223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:9AE66583C89B7A0D|rigid:UgiPWQ0Qo4nYwH2k+r2jBbWi8r0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83970 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596222|imex:IM-9152-214 author score:0.399992018 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:4D05A3D29CDCDF47|rigid:pTNeIZRt2zcIOX5rKlP1slERGE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83910 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596228|imex:IM-9152-215 author score:0.274707055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:FBBF11147AF72AEE|rigid:4b7yh97VwsIQQ8Oebi52utM5q+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83312 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596234|imex:IM-9152-216 author score:0.215186659 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:0CD22C5F8FDB0280|rigid:AKXB6Q+fxsv3U2DiSmEsfjRmJDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83877 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596252|imex:IM-9152-219 author score:0.101343805 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:23D80D79182595E1|rigid:uE5ExoPt1NGNTvMnP6Cdwjzk64Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83910 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596246|imex:IM-9152-218 author score:0.151266804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:E6E57EBC3BE857A6|rigid:lTjZnv0usHAv7BBOzT2qcENscgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83927 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596240|imex:IM-9152-217 author score:0.185065578 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:832080CAD74F75D5|rigid:S+l1FmctMd856Fv+Biyt3zNjOwg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83910 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596264|imex:IM-9152-221 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:C9C3CE35E1B9B53F|rigid:XAcA/+P0jbJ3dSy/NJawS+6O8Cw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83767 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596258|imex:IM-9152-220 author score:0.058708063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:886F7F3613C8F13F|rigid:2rPW1UFf7EMIqxCeusAT3yA9i8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83910 uniprotkb:O83954 intact:EBI-1596205|ensemblbacteria:AAC65899 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596270|imex:IM-9152-222 author score:0.016840989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4DB75A9E131B8221|rigid:6e0rGXw/1yq2f91ivt8Xi6YyyAc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83910 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596276|imex:IM-9152-223 author score:0.001013011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0940; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:C82F509FEDB3CD29|rigid:SJO0kGK2XgN2liFHK/ztRGjl5j4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83165 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1596282|ensemblbacteria:AAC65120 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596291|imex:IM-9152-225 author score:0.497258971 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 intact-crc:0D1D224F047D59FD|rigid:zDu6jqx3/CuEd1T0utAxvdB5m2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83106 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596285|imex:IM-9152-224 author score:0.596974104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:498065212A80926D|rigid:/Y2JXfyAyM7cyhFgDikMlWfDdho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83165 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1596282|ensemblbacteria:AAC65120 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596309|imex:IM-9152-228 author score:0.232267228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 intact-crc:61A01F9396A9F94B|rigid:6dauUVbaWaf/lgeP/vuFchJu0lA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83165 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1596282|ensemblbacteria:AAC65120 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596297|imex:IM-9152-226 author score:0.483803375 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 intact-crc:2FD4607FD4069592|rigid:HszWt8YiivzkZROMXpM1xkSLIhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83398 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596303|imex:IM-9152-227 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:09DEDCF29B3F3C12|rigid:0xsHhe9Y66zi3cmcsmkEhn6TzD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83413 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596315|imex:IM-9152-229 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:5CC544754C062D74|rigid:COeZf7Q31Y0OxJyC7Hd2hNy4ppg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83667 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596321|imex:IM-9152-230 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C0172D1C25DA34E8|rigid:O4zq9tb/nZcL6XrV93UKh+VSVE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83767 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596327|imex:IM-9152-231 author score:0.066028043 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:84A37BDED327EF6D|rigid:rcpySwWfHqs6upSXRiZdYJBL3ts false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83165 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1596282|ensemblbacteria:AAC65120 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596333|imex:IM-9152-232 author score:0.055314123 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 intact-crc:2A23ACD8764275CB|rigid:uyLzvhdfSYLBOJanoW3haHAarjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83958 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596345|imex:IM-9152-234 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:2D734A7F40ABD187|rigid:PzbfGGoXCY8PnWwABhaVNFsBueE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83165 uniprotkb:O83954 intact:EBI-1596282|ensemblbacteria:AAC65120 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y128_trepa(display_long)|uniprotkb:TP_0128(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596339|imex:IM-9152-233 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65120(transcript)|ensemblbacteria:TP_0128(gene)|refseq:WP_010881577.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0128; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cUcimvxWlZvrwAOTa9rs6kXvBcA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:17B6062EAD923619|rigid:LJo05IFG6XlSRpNrLndBz5NhZg8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83939 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596357|imex:IM-9152-236 author score:0.570816448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:B03B3532111C6ECD|rigid:r7o6CmIPH3rvY7Di1Tsf7giL0WI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83542 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596351|imex:IM-9152-235 author score:0.596974104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:F1FA006D01DFCBA5|rigid:JQYolgarFO8ipV5Oy6d5rP5xckQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83982 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596363|imex:IM-9152-237 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:120BE7AF06ADEAC9|rigid:YVz9zkt/9nCGqDCyJ/y5iEXXNHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83312 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596369|imex:IM-9152-238 author score:0.237102582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:3B78E14C17C717E8|rigid:2k2iMtjNp9/kC5uYbbQ0TPJ//bg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83542 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596375|imex:IM-9152-239 author score:0.227501077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:EA65821A277C8883|rigid:zMRBpx3q4icfxeq7qqvsJGYJdSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83542 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596393|imex:IM-9152-1179 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:B5237F8A08E50368|rigid:B02A1OjWmNk0rs7v9ZQ4QIBhjdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83542 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596381|imex:IM-9152-585 author score:0.204713982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:19C289916CAE740B|rigid:1dQ7nQAF/oNdZzgJtD3qnzeOj58 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83542 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596387|imex:IM-9152-1178 author score:0.168066845 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:973513DBA31D4993|rigid:nyrxFOgnhIDVjNTSSkSETV0eP+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83282 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596405|imex:IM-9152-1181 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:C7E0EB75EDFB00BC|rigid:GDLoBc74XzwNhokDJYu/id0or4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83667 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596399|imex:IM-9152-1180 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:3445523A1BFE5A72|rigid:imI+mJGU1kaA6g9tbwVPMDHVyik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83954 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596411|imex:IM-9152-1182 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0530; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:E3E4790893B65883|rigid:JFPHxjfqY+p7j1ypYpYix4IT+J4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83928 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596420|imex:IM-9152-1183 author score:0.590360819 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:D6FE812F8704B661|rigid:v9tl3GDPBM6X8zoKItqPU3SqGS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83928 uniprotkb:O83305 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596426|imex:IM-9152-1184 author score:0.347357628 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:B1A26B548571431E|rigid:rbiRj7ETLbey4iITwEbf4ERn5o4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83928 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596432|imex:IM-9152-1185 author score:0.272759532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:96E882FC4ABE87E5|rigid:7QsdZw7iTjLH0TLqIlY8fOtWHe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83928 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596438|imex:IM-9152-1186 author score:0.163176131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:9316730D893E6527|rigid:02YtpL1t1W8lZxcmuAp1iFbe3YY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83928 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596450|imex:IM-9152-1188 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:E3325870698B85E0|rigid:c8iSoLy0MMjEgztgeLA4YaKHlYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83928 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596444|imex:IM-9152-1187 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:6E84D1828FA9D9C2|rigid:n9t6JeUKtd8i9XfVLt7X2PekEzE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83928 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596462|imex:IM-9152-1190 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:6D1ED47F1F7296EF|rigid:fvVqonNoMqWX0i6lgw8H1xZ4Tok false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83928 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1596417|ensemblbacteria:AGN76127|ensemblbacteria:AAC65917 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83928_trepa(display_long)|uniprotkb:TP_0962(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596456|imex:IM-9152-1189 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|interpro:IPR025857|ensemblbacteria:AGN76127(transcript)|ensemblbacteria:TP_0962(gene)|ensemblbacteria:TPANIC_0962(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:AAC65917(transcript)|refseq:WP_010882406.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0962; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:zPCb5wZ3/ccYfFgPunWMQgBNM1U243276 intact-crc:0B77BE5C2990D35D|rigid:hlyUzBiADApxSJs9E0V2h05gyes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83192 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596468|imex:IM-9152-1191 author score:0.586212783 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 intact-crc:E718755BD1DB9AE7|rigid:ttLrZWVD6t1SnyUaCuGz1tS6850 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83570 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596477|imex:IM-9152-1192 author score:0.519766244 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:EE7C87D967E671DA|rigid:pBowWYRyDaHv7f8YCvzHU4mcI9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83752 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596483|imex:IM-9152-1193 author score:0.492854561 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:330FC44F4D0A3787|rigid:ipNgH/z1bJmMDuA0wpt5SCYjZ8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83463 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596489|imex:IM-9152-1194 author score:0.355727749 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:1535607589D5537D|rigid:O019XKX0oWTmn8YMz8qQwHeoHzY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83192 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596495|imex:IM-9152-1195 author score:0.274707055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 intact-crc:44A2BCE02E13CF4F|rigid:u2nS02bd+gyilQup115LLXKLJwI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83192 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596501|imex:IM-9152-1196 author score:0.229140169 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 intact-crc:FF93A830EBC43590|rigid:cSuOdEjOQZYvRZlzgemWaT59+yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83099 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596507|imex:IM-9152-1197 author score:0.210674823 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:0B48753A7AAB0F2D|rigid:VYcsX+6mhP97iawsMa24VK3TkcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83192 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596513|imex:IM-9152-1198 author score:0.206232729 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 intact-crc:83754C07DE71B016|rigid:UMu8NjD7rXsAOL0tljK7r8IzQrE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83574 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596519|imex:IM-9152-1199 author score:0.151266804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:FA356BB0E379B521|rigid:OO+bjH1j2h08AtI9iO+gbrULoSM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83877 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596525|imex:IM-9152-1200 author score:0.101343805 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B2F2FF19C074D995|rigid:bjQuMqmAFjBulT+8AiPJplCa8jo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83192 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596537|imex:IM-9152-1202 author score:0.016840989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 intact-crc:F2AAF76A47FF6780|rigid:Thi43SOWrwHrI2tEYNh/u+Fj2v0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83282 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596531|imex:IM-9152-1201 author score:0.020262798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:E5F5C7FDF00655D6|rigid:6xtiC2L7Tl2NeOAPUc8TPw95Xsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83079 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1586680|ensemblbacteria:AAC65031 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:y036_trepa(display_long)|uniprotkb:TP_0036(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596549|imex:IM-9152-1204 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001626(ABC-3)|ensemblbacteria:AAC65031(transcript)|ensemblbacteria:TP_0036(gene)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|refseq:WP_010881485.1|interpro:IPR037294 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0036; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:c0I8SrM7uCvFiIAIeEx0w2T9LPc243276 intact-crc:52DB47BE9F90D819|rigid:gGRYzuF30QR/fH+Xr/KAoqpRPi4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83183 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1586606|ensemblbacteria:AAC65140 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:y148_trepa(display_long)|uniprotkb:TP_0148(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596555|imex:IM-9152-1205 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65140(transcript)|ensemblbacteria:TP_0148(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881595.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0148; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:Uj76HnVA1pIu+VetvJ6w7DCMeCY243276 intact-crc:EB03D5B006FF3228|rigid:37CdYjaqRUZ00/6SghImkTsm0Ps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83192 uniprotkb:O83958 intact:EBI-1596472|ensemblbacteria:AAC65147|ensemblbacteria:AGN75376 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83192_trepa(display_long)|uniprotkb:TP_0157(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596543|imex:IM-9152-1203 author score:0.001013011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002123(Phospholipid/glycerol acyltransferase)|ensemblbacteria:AAC65147(transcript)|ensemblbacteria:AGN75376(transcript)|ensemblbacteria:TP_0157(gene)|ensemblbacteria:TPANIC_0157(gene)|go:"GO:0016746"(acyltransferase activity)|refseq:WP_010881604.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0157; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9KFZfIz/Yjs3urM43QlUE5cjgQY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7732FD6BB9572888|rigid:cTqhBNvLTSQ9Di2Ppb4EylEqv5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83263 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1596565|ensemblbacteria:AAC65223 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:sece_trepa(display_long)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:TP_0235(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596561|imex:IM-9152-1206 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005807(SecE subunit of protein translocation complex)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR038379|ensemblbacteria:AAC65223(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|ensemblbacteria:TP_0235(gene)|refseq:WP_010881683.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0235; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:EViPo7r7knLF1Z36NVvBTEOwDWc243276 intact-crc:972C3BEE964C7342|rigid:4Qbjn/ApIz6IlN1g40hfHnGpYhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83334 uniprotkb:O83572 intact:EBI-1596571|ensemblbacteria:AAC65299|ensemblbacteria:AGN75515 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83334_trepa(display_long)|uniprotkb:TP_0312(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596574|imex:IM-9152-1207 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007163(Protein of unknown function DUF368)|ensemblbacteria:AAC65299(transcript)|ensemblbacteria:AGN75515(transcript)|ensemblbacteria:TP_0312(gene)|ensemblbacteria:TPANIC_0312(gene)|refseq:WP_010881761.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0312; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pZBhZvFd8DoJJu2W+idTm35H+Dw243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:15CD3D5B1C081E02|rigid:0lTc1/DBQH6UbbIcOBQqSkgv9J4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83512 uniprotkb:O83572 intact:EBI-1582576|ensemblbacteria:AAC65486|ensemblbacteria:AGN75689 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83512_trepa(display_long)|uniprotkb:TP_0499(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596589|imex:IM-9152-1209 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017225(Cell shape-determining protein MreD, predicted)|interpro:IPR007227(Cell shape-determining protein MreD)|ensemblbacteria:AAC65486(transcript)|ensemblbacteria:AGN75689(transcript)|ensemblbacteria:TP_0499(gene)|ensemblbacteria:TPANIC_0499(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881948.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0499; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gsifFJ+3XwpDmrTw4ngHj7sGTDI243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:4D5528945DB4E711|rigid:f5/U4s/0sV8xbj3oatQPpEzmM1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83445 uniprotkb:O83572 intact:EBI-1596584|ensemblbacteria:AAC65416|ensemblbacteria:AGN75624 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83445_trepa(display_long)|uniprotkb:TP_0430(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596580|imex:IM-9152-1208 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|ensemblbacteria:AAC65416(transcript)|ensemblbacteria:AGN75624(transcript)|ensemblbacteria:TP_0430(gene)|ensemblbacteria:TPANIC_0430(gene)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033177"(proton-transporting two-sector ATPase complex, proton-transporting domain)|refseq:WP_010881878.1|interpro:IPR035921 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0430; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:WyPLJ7ckVOCpMLimkM2iFUKbyzU243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:CA181F91D9F6835E|rigid:g+n8R+HD+u+cl6wJS4Q49bNjMYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83566 uniprotkb:O83572 intact:EBI-1596599|ensemblbacteria:AAC26559 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83566_trepa(display_long)|uniprotkb:TP_0555(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596595|imex:IM-9152-1210 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001991("Sodium:dicarboxylate symporter")|ensemblbacteria:AAC26559(transcript)|ensemblbacteria:TP_0555(gene)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882002.1|interpro:IPR036458 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0555; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:b6T1VZFyFuZ16VjV/gRxyzkVAnM243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:3C2B649076E12F40|rigid:Kz3i6xfk17ClYVTonSGfyg/CetI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83609 uniprotkb:O83572 intact:EBI-1596608|ensemblbacteria:AAC65573 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y600_trepa(display_long)|uniprotkb:TP_0600(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596604|imex:IM-9152-1211 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004387(Peptidase M50, putative membrane-associated zinc metallopeptidase)|interpro:IPR008915(Peptidase M50)|ensemblbacteria:AAC65573(transcript)|ensemblbacteria:TP_0600(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882046.1|interpro:IPR036034|interpro:IPR041489 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0600; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hkDIsxkLzHelag5KK+9SUkZqnd8243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:ABFCE531382CF234|rigid:7EKKKn1BKj3kUsHcv5CWVhwuS1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83447 uniprotkb:O83970 intact:EBI-1585025|ensemblbacteria:AAC65420 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y432_trepa(display_long)|uniprotkb:TP_0432(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596613|imex:IM-9152-1212 author score:0.585734108 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65420(transcript)|ensemblbacteria:TP_0432(gene)|refseq:WP_010881880.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0432; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:C9WqS8T1hASpueWfFwanX4vNYXE243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:5D1D54FAEB5C8913|rigid:IlfKDvnE4BhcR9Bz4oE2PTm7rXY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O07896 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596623|imex:IM-9152-1213 author score:0.58440605 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:84246449CF3AF299|rigid:5HyUJnEfzC31PP2TBfKoodIi3vU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83133 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596629|imex:IM-9152-1214 author score:0.51787162 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:9596630D0FADE510|rigid:xIatUrw3nVw3Dx2ouElggMETazM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83525 uniprotkb:O07896 intact:EBI-1596639|ensemblbacteria:AAC65500 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:ispdf_trepa(display_long)|uniprotkb:ispDF(gene name)|psi-mi:ispDF(display_short)|uniprotkb:TP_0512(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596635|imex:IM-9152-1215 author score:0.468791231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018294|interpro:IPR003526(2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core)|interpro:IPR020555|interpro:IPR034683|ensemblbacteria:AAC65500(transcript)|ensemblbacteria:TP_0512(gene)|go:"GO:0008685"(2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050518"(2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity)|interpro:IPR029044|interpro:IPR036571 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0512|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:k1c41TB+PTGeTsGUVH014w7rMPs243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:F673547156D14AA1|rigid:gK4IsqAsZKJIp8mA+n3MF8vCsA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83676 uniprotkb:O07896 intact:EBI-1596649|ensemblbacteria:AAC26568 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:ddl_trepa(display_long)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)|uniprotkb:ddlA(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:TP_0670(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596645|imex:IM-9152-1216 author score:0.468791231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011127(D-alanine--D-alanine ligase, N-terminal)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|ensemblbacteria:AAC26568(transcript)|ensemblbacteria:TP_0670(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008716"(D-alanine-D-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882115.1 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0670|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:3zdRrMBrjY/9kju33T37PHuMZ3A243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:68E770026FA373A1|rigid:QD8zxgiKRiZy7t0IsEW//PH2y1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O07896 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596658|imex:IM-9152-1217 author score:0.468791231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_1002|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:C530B384C88D542D|rigid:IR10dkg2o4r19ymaGsO4GuBa79M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83526 uniprotkb:O07896 intact:EBI-1592146|ensemblbacteria:AAC65501|ensemblbacteria:AGN75702 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83526_trepa(display_long)|uniprotkb:TP_0513(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596670|imex:IM-9152-1219 author score:0.448739483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|ensemblbacteria:AAC65501(transcript)|ensemblbacteria:AGN75702(transcript)|ensemblbacteria:TP_0513(gene)|ensemblbacteria:TPANIC_0513(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|refseq:WP_010881962.1|interpro:IPR036291|interpro:IPR036721 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0513|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a4ai6430LAmmKePJdR/ZjwQF/H0243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:25A102AD53CB63E4|rigid:7RIEcmTB2oX7T8cEkTCxxNDYDqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83414 uniprotkb:O07896 intact:EBI-1198353|intact:EBI-1581603|ensemblbacteria:AAC65387 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:flif_trepa(display_long)|uniprotkb:fliF(gene name)|psi-mi:fliF(display_short)|uniprotkb:TP_0399(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596664|imex:IM-9152-1218 author score:0.462092867 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013556(Flagellar M-ring C-terminal)|interpro:IPR000067(Flagellar FliF M-ring protein)|interpro:IPR006182(Secretory protein YscJ/FliF)|refseq:WP_010881847.1|interpro:IPR043427|ensemblbacteria:AAC65387(transcript)|ensemblbacteria:TP_0399(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009431"(bacterial-type flagellum basal body, MS ring)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0399|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kreI83O50O7NxlQh3Qhq2WFPKNE243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:902B3D52DA79F772|rigid:9QixuFEf4zcc+5S8zbJi2lcAkck false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O52778 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1198452|intact:EBI-1582080|uniprotkb:Q7DFP3 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o52778_trepl(display_long)|uniprotkb:mcp4(gene name)|psi-mi:mcp4(display_short)|uniprotkb:FA889_03315(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596676|imex:IM-9152-1220 author score:0.442089186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR004090(Chemotaxis methyl-accepting receptor)|interpro:IPR004089(Chemotaxis methyl-accepting receptor, signalling)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882085.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0640|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:1L4P4tShLbFX9YkRRP1wS/2w3JU160 intact-crc:A115E2735FADD0A3|rigid:Hzny+wdzO+xS3YHothS0o0MyWnk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83890 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1583720|ensemblbacteria:AAC65878 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596682|imex:IM-9152-1221 author score:0.428852997 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 intact-crc:E5DE898E6BE68ED1|rigid:i5xUB8hX/D1NISRSB7bgvkOnAE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O07896 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596688|imex:IM-9152-1222 author score:0.39624284 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:5FADE288D36679BA|rigid:ooabSUurKaA+FOsVCGVnYV4lDjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O07896 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596700|imex:IM-9152-1224 author score:0.266307318 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:73374A0D16BCB1C9|rigid:VdcXbq4u0zkH9iyef9ZtRhn/eRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83275 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596694|imex:IM-9152-1223 author score:0.346032576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:BAF822554C01CB2B|rigid:rs64OnCDDPg5P3JiIDuzbz+wZwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83463 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596712|imex:IM-9152-1226 author score:0.186772231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:5CFFB84BE6527976|rigid:glF7tviWoROl2jxgYUiAQ6VGvDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83970 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596706|imex:IM-9152-1225 author score:0.217097086 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:83B1A3E18A0AEFEB|rigid:Ef0cbtr88qwbwEMvjZTYEhe4BA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83398 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596718|imex:IM-9152-1227 author score:0.136103654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:C42C9F0B62DAC095|rigid:Vqy0/S3aMdPS6DEAEriubXAydKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O07896 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596724|imex:IM-9152-1228 author score:0.132621674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:65434B667326F023|rigid:mS8K4rPB8128HXuqyEKM5pF2Cwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O07896 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596730|imex:IM-9152-1229 author score:0.121036798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:2D2224D8C47BD7A5|rigid:W779whzrRk7hGsJjgyOkgo33AX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83312 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596736|imex:IM-9152-1230 author score:0.102375376 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:C07F6661B97EF936|rigid:b/Dm3iB81W+ftHyWRPvpoF8yv3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:P21992 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596742|imex:IM-9152-1231 author score:0.097532176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:B64CB183A5E22A1A|rigid:Jqr2gfpTsbNUD1mCrEBYvsYdz+I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83927 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596748|imex:IM-9152-1232 author score:0.086308643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:2A9CDBFBC7CF01F3|rigid:I299jKjL1xDkKn8HNdNJHkSO9eI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O07896 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596754|imex:IM-9152-1233 author score:0.040417425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:812BD9BD3A770471|rigid:vQp8vWjFLSOGyfQ1b0t2ukD2vds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83767 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596766|imex:IM-9152-1235 author score:0.025287264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:DD5BA258623E0E73|rigid:GW2R32plpkVLAawe8APPZ2OwB5o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83667 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596760|imex:IM-9152-1234 author score:0.037398649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:23A72E33E41F47CB|rigid:cz/Hi2ztNHgAzyNajuAyP1e9GtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O07896 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1596619|ensemblbacteria:AAC65782 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596772|imex:IM-9152-1236 author score:0.021035184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 intact-crc:74F7B0FDF071A85F|rigid:7r9CmsZhLcT+Maqf0IPcLip0Jus false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83282 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596778|imex:IM-9152-1237 author score:0.008529458 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9AE1977C811C4547|rigid:ZUv/jUhXyM2sjGu7KDFd0WpxzZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83954 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596784|imex:IM-9152-1238 author score:0.007074768 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:443B1870E3ECBBA7|rigid:33TyoHOVmo4NGbRt+fwOwbFBuXc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07896 uniprotkb:O83958 intact:EBI-1596619|ensemblbacteria:AAC65782 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rnz_trepa(display_long)|uniprotkb:rnz(gene name)|psi-mi:rnz(display_short)|uniprotkb:tRNase Z(gene name synonym)|uniprotkb:tRNA 3 endonuclease(gene name synonym)|uniprotkb:TP_0819(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596790|imex:IM-9152-1239 author score:0.000587236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001279(Beta-lactamase-like)|interpro:IPR013471(Ribonuclease Z)|ensemblbacteria:AAC65782(transcript)|ensemblbacteria:TP_0819(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|interpro:IPR036866 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0819; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D/hA/EJa25Y/UcNsYUJmJmZjJzk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D8803B8248AB33B6|rigid:vY7rF0JvJ7nAmlESvdHEVD0bpL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:P74936 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1596800|ensemblbacteria:AAC65336 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:prob_trepa(display_long)|uniprotkb:proB(gene name)|psi-mi:proB(display_short)|uniprotkb:Gamma-glutamyl kinase(gene name synonym)|uniprotkb:TP_0351(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596806|imex:IM-9152-1241 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR019797|ensemblbacteria:AAC65336(transcript)|ensemblbacteria:TP_0351(gene)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010881799.1|interpro:IPR036393|interpro:IPR041739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0351; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:Gs4QQVxBlp1GqoZ1pX1Baj23hcU243276 intact-crc:97B6C07A0A942B78|rigid:zJ99NVm5XWKxKE3cMj6mqFWPWk0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74936 uniprotkb:O83738 intact:EBI-1596800|ensemblbacteria:AAC65336 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:prob_trepa(display_long)|uniprotkb:proB(gene name)|psi-mi:proB(display_short)|uniprotkb:Gamma-glutamyl kinase(gene name synonym)|uniprotkb:TP_0351(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596796|imex:IM-9152-1240 author score:0.577158366 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR019797|ensemblbacteria:AAC65336(transcript)|ensemblbacteria:TP_0351(gene)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010881799.1|interpro:IPR036393|interpro:IPR041739 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0351; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Gs4QQVxBlp1GqoZ1pX1Baj23hcU243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:7B11129A7D0C73F3|rigid:hGVvb6AQSECgVq3dk295rAVPLmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:P74936 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1596800|ensemblbacteria:AAC65336 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:prob_trepa(display_long)|uniprotkb:proB(gene name)|psi-mi:proB(display_short)|uniprotkb:Gamma-glutamyl kinase(gene name synonym)|uniprotkb:TP_0351(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596812|imex:IM-9152-1242 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR019797|ensemblbacteria:AAC65336(transcript)|ensemblbacteria:TP_0351(gene)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010881799.1|interpro:IPR036393|interpro:IPR041739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0351; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Gs4QQVxBlp1GqoZ1pX1Baj23hcU243276 intact-crc:69773F750F0C4BF5|rigid:2SMCnEZC8/R5y5oPs405GQTBARo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74936 uniprotkb:O83958 intact:EBI-1596800|ensemblbacteria:AAC65336 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:prob_trepa(display_long)|uniprotkb:proB(gene name)|psi-mi:proB(display_short)|uniprotkb:Gamma-glutamyl kinase(gene name synonym)|uniprotkb:TP_0351(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596824|imex:IM-9152-1244 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR019797|ensemblbacteria:AAC65336(transcript)|ensemblbacteria:TP_0351(gene)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010881799.1|interpro:IPR036393|interpro:IPR041739 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0351; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Gs4QQVxBlp1GqoZ1pX1Baj23hcU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:FE8365F8B4A2DE9D|rigid:ezoWH2AH/gpjoLtiTMeFGP8I3uY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:P74936 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1596800|ensemblbacteria:AAC65336 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:prob_trepa(display_long)|uniprotkb:proB(gene name)|psi-mi:proB(display_short)|uniprotkb:Gamma-glutamyl kinase(gene name synonym)|uniprotkb:TP_0351(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596818|imex:IM-9152-1243 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR011529(Glutamate 5-kinase, pro-B)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR019797|ensemblbacteria:AAC65336(transcript)|ensemblbacteria:TP_0351(gene)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010881799.1|interpro:IPR036393|interpro:IPR041739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0351; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:Gs4QQVxBlp1GqoZ1pX1Baj23hcU243276 intact-crc:0C91B21336780F25|rigid:MXWAfINpahf+tbmDOabhik8mX7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83122 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596833|imex:IM-9152-1245 author score:0.575368509 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:DB7944420AFB3FAA|rigid:7+3clRvKYQYxzEfISi8J1Oy7C3U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83122 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596839|imex:IM-9152-1246 author score:0.522087915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:65756559B38F6973|rigid:bnre6pnl8ZwQ+HyEKRTH4Pz8eZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83122 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596845|imex:IM-9152-1247 author score:0.508640202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:3A7FC9FF07F750C5|rigid:qkKfZfxrkEJARfiHJsYpwpqvFug false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83122 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596851|imex:IM-9152-1248 author score:0.501910434 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:C987642AC0A69ED9|rigid:rHLCxif8zQz1nK8JPfJMbpj0gLA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83122 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596863|imex:IM-9152-1250 author score:0.434974615 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:E5133B4674DA8C8A|rigid:uryGhlu9RBNl+Y+rZiitVpOWQE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83709 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596869|imex:IM-9152-1251 author score:0.357862712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:4E45C5FC7AA1F65A|rigid:aGumUB5ZOVNVQynENOZ9woRapuk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83459 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596857|imex:IM-9152-1249 author score:0.46160248 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:E19C3EE3570F9E31|rigid:HI6yMO5C+um2+edbwDu/eUS+9l8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83305 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596875|imex:IM-9152-1252 author score:0.255544357 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:2E299AF80E11715D|rigid:s7RMyf/QZde4Kmc8XkeF0b2B+JI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83531 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596881|imex:IM-9152-1253 author score:0.226042815 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:E6DE71018AC1504F|rigid:czY66Oz4lIQuQxOFDNy1+aQvZKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83877 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596893|imex:IM-9152-1255 author score:0.090487982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:278CE27EB9DA15AC|rigid:W5C9REVMf4c7UIS5/fY8sWcjLjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83122 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596887|imex:IM-9152-1254 author score:0.190591409 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:11E30C14365AA6A6|rigid:24CA+UMdFhCYcd341sR9PYMBQpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83667 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596905|imex:IM-9152-1257 author score:0.076128626 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:7EA96A9D2A445B9B|rigid:gqldoeXVlUOOj101WpM7ih0EsJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83122 uniprotkb:O83413 intact:EBI-1596830|ensemblbacteria:AAC65088 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596899|imex:IM-9152-1256 author score:0.082007308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:3B34AD3FEA51C992|rigid:C040tYjnAvohOK1De7xcQ8Cik64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83122 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596917|imex:IM-9152-1259 author score:0.000893809 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:549A67D07C4C9A25|rigid:Q12jZonQX3hzMnBcBGeIsERkT8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83122 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1596830|ensemblbacteria:AAC65088 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y084_trepa(display_long)|uniprotkb:TP_0084(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596911|imex:IM-9152-1258 author score:0.043586496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010881533.1|ensemblbacteria:AAC65088(transcript)|ensemblbacteria:TP_0084(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0084; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:o7xTzm7negRhr0g0iSNAYH+uWuA243276 intact-crc:94F1B0FF59CA2340|rigid:Jp6HqkYpnYUGv0mrVCg26LP+zJY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83100 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1583370|ensemblbacteria:AAC65056 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596923|imex:IM-9152-1260 author score:0.575127466 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 intact-crc:F131536256F666A6|rigid:U8W+k+YaFZCFXmIQqSQnJBDBt/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83982 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596929|imex:IM-9152-1261 author score:0.458153543 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:3DE2D64BA64C18AA|rigid:lTfuHho+vCC+WWwA59WPziFdlrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83100 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1583370|ensemblbacteria:AAC65056 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596935|imex:IM-9152-1262 author score:0.448007483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 intact-crc:74AD5B4E5EA18C4D|rigid:zBCaOfgDv3gm9o0DLXOCNDJkxq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83100 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1583370|ensemblbacteria:AAC65056 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596941|imex:IM-9152-1263 author score:0.388972037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 intact-crc:92169CBFAA12D037|rigid:wIn1X5LyW6MyRoG28gtFstJehEo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83312 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596947|imex:IM-9152-1264 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:22BD9397482E60E6|rigid:pTDNaCnpExlzYJwD+KG5o2y83wc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83767 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596953|imex:IM-9152-1265 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0174CB71063564A4|rigid:Ulnq6mZp+qfcbtcrC7HXVgRug8U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83954 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596965|imex:IM-9152-1267 author score:0.02153435 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:ECAB45EF7E8E14C1|rigid:r2s2BKNUF6IKOM6gNXOxHMyuMhs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83100 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1583370|ensemblbacteria:AAC65056 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596959|imex:IM-9152-1266 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 intact-crc:E3339F8BD0BE6E9B|rigid:sj/pzxwAWjLwZ/c0bubPxImRkPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:Q56328 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1596981|ensemblbacteria:AAC65287 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596977|imex:IM-9152-1269 author score:0.575127466 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 intact-crc:DF21117748EC6250|rigid:szpTyq+g0PmBPkRmsK428OwHmmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83100 uniprotkb:O83958 intact:EBI-1583370|ensemblbacteria:AAC65056 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rs18_trepa(display_long)|uniprotkb:rpsR(gene name)|psi-mi:rpsR(display_short)|uniprotkb:TP_0061(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596971|imex:IM-9152-1268 author score:0.001818538 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001648(Ribosomal protein S18)|ensemblbacteria:AAC65056(transcript)|ensemblbacteria:TP_0061(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881510.1|interpro:IPR036870 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0061; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nfO19hY+wlzr5jc3CmrpgpRfSZQ243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B49147A480CE7600|rigid:Nq9SLViR6DsgfEl/LtXPgqpXZlE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:Q56328 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1596981|ensemblbacteria:AAC65287 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596987|imex:IM-9152-1270 author score:0.51512044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 intact-crc:01F76AE8289E4801|rigid:u8OgPi+P+e5PKRv3brcDeh/6DkU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56328 uniprotkb:O83398 intact:EBI-1596981|ensemblbacteria:AAC65287 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596993|imex:IM-9152-1271 author score:0.327337582 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:98F21F0D5BF6A5BA|rigid:PciMxXD2KAGLyvBdNPDAZhIC4VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:Q56328 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1596981|ensemblbacteria:AAC65287 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597005|imex:IM-9152-1273 author score:0.27275983 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 intact-crc:22CE33E04D7DDEAA|rigid:luiBgzdBF1VJPSupZW8QGRAZtvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:Q56328 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1596981|ensemblbacteria:AAC65287 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1596999|imex:IM-9152-1272 author score:0.298413524 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 intact-crc:D602FDECDA95883A|rigid:X5p1W9qKxg/JIoz7Y1ITbDe5Mis false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56328 uniprotkb:O83312 intact:EBI-1596981|ensemblbacteria:AAC65287 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597011|imex:IM-9152-1274 author score:0.260509653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:9E6D3C52450488CF|rigid:Ly/41mrTpc6NhGY97/mdSuJONu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:Q56328 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1596981|ensemblbacteria:AAC65287 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597023|imex:IM-9152-1276 author score:0.074188775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 intact-crc:E6696A45BCA60C2E|rigid:LWaO8aKgu7ywpqM/zvcJn1aa0OQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56328 uniprotkb:O83667 intact:EBI-1596981|ensemblbacteria:AAC65287 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597017|imex:IM-9152-1275 author score:0.107146989 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B2449B3AEF9F864B|rigid:oRZ1EUeGP/qKc+0+546ZeRUoXgA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q56328 uniprotkb:O83282 intact:EBI-1596981|ensemblbacteria:AAC65287 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rfua_trepa(display_long)|uniprotkb:rfuA(gene name)|psi-mi:rfuA(display_short)|uniprotkb:"Membrane lipoprotein TpN38(b)"(gene name synonym)|uniprotkb:tpn38(gene name synonym)|uniprotkb:TP_0298(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597029|imex:IM-9152-1277 author score:0.025884665 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4IIL|interpro:IPR003760(Basic membrane lipoprotein)|ensemblbacteria:AAC65287(transcript)|ensemblbacteria:TP_0298(gene)|go:"GO:0005886"(plasma membrane)|interpro:IPR028082|refseq:WP_010881747.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0298; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MgSJyDAmRmD8oZgZi5MfGxsaHPk243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:A54D7370495D1ADB|rigid:fIPqyFBTkS7g3kU7ZNwnFe7JO7Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83639 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1590070|ensemblbacteria:AAC65606 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597035|imex:IM-9152-1278 author score:0.572865458 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 intact-crc:AF28643DD50C2C58|rigid:Y68iyuXy+IKm5tOwi3+SMDtfVqs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83639 uniprotkb:O83804 intact:EBI-1590070|ensemblbacteria:AAC65606 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597041|imex:IM-9152-1279 author score:0.555160027 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 intact-crc:EA457A28D936FC47|rigid:0duI90xnIRe6y8pPrTKHGG/5VdY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83639 uniprotkb:O83312 intact:EBI-1590070|ensemblbacteria:AAC65606 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597047|imex:IM-9152-1280 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:70FA7A2602636BCB|rigid:gA6s8xDKIUu73m241Ray24O1OIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83639 uniprotkb:O83282 intact:EBI-1590070|ensemblbacteria:AAC65606 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597059|imex:IM-9152-1282 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:BAF68AF004FD5292|rigid:coozCUaj8VlUazbWjqyPtEkVt6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83639 uniprotkb:O83745 intact:EBI-1590070|ensemblbacteria:AAC65606 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597053|imex:IM-9152-1281 author score:0.161866751 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:74FFF72D554F7283|rigid:m8aCoTHsfDfw6is2joENm+CobKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83588 uniprotkb:O83709 intact:EBI-1198338|intact:EBI-1582986|ensemblbacteria:AAC65559 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y579_trepa(display_long)|uniprotkb:TP_0579(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597071|imex:IM-9152-1284 author score:0.572611239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882025.1|ensemblbacteria:AAC65559(transcript)|ensemblbacteria:TP_0579(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0579; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nWWFurIENwbhGo0ck707dXmX1Kw243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:B8167B78AFCAF198|rigid:ze9lmEE1tGopz6x/9Ck8yk4ye+8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83639 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1590070|ensemblbacteria:AAC65606 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:cheb_trepa(display_long)|uniprotkb:cheB(gene name)|psi-mi:cheB(display_short)|uniprotkb:TP_0631(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597065|imex:IM-9152-1283 author score:0.002099918 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011006(CheY-like)|interpro:IPR008248(Signal transduction response regulator, chemotaxis, CheB-like)|interpro:IPR000673(Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase)|interpro:IPR001789(Signal transduction response regulator, receiver region)|ensemblbacteria:AAC65606(transcript)|ensemblbacteria:TP_0631(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0008984"(protein-glutamate methylesterase activity)|go:"GO:0018277"(protein deamination)|go:"GO:0050568"(protein-glutamine glutaminase activity)|refseq:WP_010882077.1|interpro:IPR035909 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0631; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:gUsjMtiENDkl2LxbaHLy5BuBsI0243276 intact-crc:DC6BC1B0C5C429A0|rigid:Y/ZehkxBcs6V6z0VWxTmbIP29fw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83310 uniprotkb:O83780 intact:EBI-1588258|ensemblbacteria:AAC65268 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597077|imex:IM-9152-1285 author score:0.571058113 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:7E897BA0ED6033F9|rigid:gcw4jPtMdJeOmf9YoE3vTs/zhQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83634 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597086|imex:IM-9152-1286 author score:0.551170744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:E643521F84CC6B9C|rigid:uhIOe54UNHvYhpZ8FoAXU7yJ8FQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83542 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597098|imex:IM-9152-1288 author score:0.504236091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:F4731921692DCB76|rigid:meWmofS508tG0m9quNv6lx1WHG4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08255 uniprotkb:O83780 intact:EBI-1584220|ensemblbacteria:AAC65647 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597092|imex:IM-9152-1287 author score:0.531118397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:D9D3A0A449031E3F|rigid:2ph/LXt4MWrGCgFLnFsDQ/jZxio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83780 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597110|imex:IM-9152-1290 author score:0.430649313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:B24781CA6C1061EB|rigid:MPsrvTg2+CrMxKbo/07RBt/jGIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83780 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597104|imex:IM-9152-1289 author score:0.430649313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:8E791ECE2423A374|rigid:aCd3BujlssTwc4bNKyYgCzJHg04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83780 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597116|imex:IM-9152-1291 author score:0.430649313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:CDD89ADA351D4B92|rigid:IKvyyaFIGaU5L23An3ROphagyZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83780 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597122|imex:IM-9152-1292 author score:0.410966854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:C7B92CB8F912044B|rigid:7x40gITYYNkluj8bzYgfOm89hGs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83670 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597128|imex:IM-9152-1638 author score:0.404465623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:903C8AEA744A6EAB|rigid:SFG6V1dF1WCO2ieYZIDl5ekxzRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83780 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597134|imex:IM-9152-1639 author score:0.391565294 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:EB2911013670FB53|rigid:R84ipVd9XXAv7og2iQDmPqpZ2eQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83463 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597140|imex:IM-9152-1640 author score:0.300572225 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:119118350BEED415|rigid:fkeiQPJb3d7jKMix8bZdkz5MKog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83780 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597146|imex:IM-9152-1641 author score:0.232443189 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:6887FDC2E8C42BF9|rigid:rgs8kdsi0mqXqc2Y/cWYFcyp8Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83531 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597152|imex:IM-9152-1642 author score:0.20487464 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:C35D4ABE5461D238|rigid:07lyENFGF19RSBibtpxWyQHA0q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83780 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597158|imex:IM-9152-1643 author score:0.121818779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:5FC269211217DD87|rigid:FFUvMDXTtaZ4M8TmOxEVRCHtFf8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83413 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597164|imex:IM-9152-1644 author score:0.073054404 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:5A4734CFE7F4A90C|rigid:b1zzon5EWagZsBm4cbc43BzaO4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83780 uniprotkb:O83667 intact:EBI-1597081|ensemblbacteria:AAC65774 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597170|imex:IM-9152-1645 author score:0.067770131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:790C0B5946894FC0|rigid:yDYFZbYBLHQ5CvqAHLgzlqR21o8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83780 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1597081|ensemblbacteria:AAC65774 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y802_trepa(display_long)|uniprotkb:TP_0802(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597176|imex:IM-9152-1646 author score:0.015842082 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65774(transcript)|ensemblbacteria:TP_0802(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0802; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:nl3z7TMVM2mmbYiwpbUd2oTm1zk243276 intact-crc:D7E7D5F6BDDE0BA7|rigid:BzrgXpQuTfZ/f4Nc90ttU7P1KGk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83606 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597182|imex:IM-9152-1647 author score:0.570816448 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:493BF666DF4B4F98|rigid:4dtZpA5oBbkpNOzN0xR23F+ysbk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83606 uniprotkb:O83459 intact:EBI-1597186|ensemblbacteria:AAC65580 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597191|imex:IM-9152-1648 author score:0.524162585 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:484F30F9E96A7D75|rigid:ZkJyIq9gTPfnFC9mhV2GEwrQhAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83606 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597197|imex:IM-9152-1649 author score:0.483803375 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:2286DC0D2475DA5D|rigid:CTDNd7qy2v4dJkd32Vtx7aRtfn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83606 uniprotkb:O83982 intact:EBI-1597186|ensemblbacteria:AAC65580 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597209|imex:IM-9152-1651 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:EB0B24FBC8FACB9C|rigid:kcROlk4B+oPBPvg4oER8GKzRJTs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83606 uniprotkb:O83305 intact:EBI-1597186|ensemblbacteria:AAC65580 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597203|imex:IM-9152-1650 author score:0.306052744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:21F93AFD7DDB4661|rigid:fwdNbTO46r0SEXEAT/XH7eXy5cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83606 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597215|imex:IM-9152-1652 author score:0.272857387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:2A040576EE0D1A5C|rigid:xTgZnDdjaSJn+vaMRfAmUT7AA7s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83606 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597221|imex:IM-9152-1653 author score:0.252020853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:179A7920D4A1FD8B|rigid:gto8biOzjUO+w7OSIvY7ONqkW6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83606 uniprotkb:O83667 intact:EBI-1597186|ensemblbacteria:AAC65580 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597227|imex:IM-9152-1654 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:CD45916ED5A97B27|rigid:eZj8fHWSYCRqRQohM3UOKPIQwfQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83606 uniprotkb:O83767 intact:EBI-1597186|ensemblbacteria:AAC65580 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597233|imex:IM-9152-1655 author score:0.066028043 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:89F1C7AC2354A0A2|rigid:4G59L1gUEIQDpsMCHKFA29VfF/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83606 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597239|imex:IM-9152-1656 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:69FE46B335F91D62|rigid:wV58IOSrSoN/yW6UOZFnjqlednQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83094 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1597255|ensemblbacteria:AAC65053 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:y055_trepa(display_long)|uniprotkb:TP_0055(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597251|imex:IM-9152-1658 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005899(Sodium ion-translocating decarboxylase)|refseq:WP_010881504.1|ensemblbacteria:AAC65053(transcript)|ensemblbacteria:TP_0055(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008948"(oxaloacetate decarboxylase activity)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036376"(sodium ion export across plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0055; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:ibu/L49AN6gnTPlu1DXIR95Kjlg243276 intact-crc:9BF03AB9902729A3|rigid:yG1Hc2uzt4lS47jQ/OrPKbm6Ono false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83606 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1597186|ensemblbacteria:AAC65580 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y597_trepa(display_long)|uniprotkb:TP_0597(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597245|imex:IM-9152-1657 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65580(transcript)|ensemblbacteria:TP_0597(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0597; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:HJSCj1fy0xc8B4eTKFRG189Sdmo243276 intact-crc:2021F60DB0D89E48|rigid:h8f3rNAwSct8JerN/0qR24BxPf4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83429 uniprotkb:O83572 intact:EBI-1584628|ensemblbacteria:AAC65402|ensemblbacteria:AGN75609 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83429_trepa(display_long)|uniprotkb:TP_0414(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597266|imex:IM-9152-1660 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001463("Sodium:alanine symporter")|ensemblbacteria:AAC65402(transcript)|ensemblbacteria:AGN75609(transcript)|ensemblbacteria:TP_0414(gene)|ensemblbacteria:TPANIC_0414(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015655"("alanine:sodium symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881862.1 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0414; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sMlFdWAkjglgnHCFAkTeld2vd4A243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:8CFEB4D84AA94850|rigid:QIXmMs0MGKjtq5jbjGaYH6mr5Jg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83094 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1597255|ensemblbacteria:AAC65053 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y055_trepa(display_long)|uniprotkb:TP_0055(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597260|imex:IM-9152-1659 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR005899(Sodium ion-translocating decarboxylase)|refseq:WP_010881504.1|ensemblbacteria:AAC65053(transcript)|ensemblbacteria:TP_0055(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008948"(oxaloacetate decarboxylase activity)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036376"(sodium ion export across plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0055; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:ibu/L49AN6gnTPlu1DXIR95Kjlg243276 intact-crc:2EA3D289EE73716A|rigid:Vw356HTXkjywnFLdUytQmCKF2Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83429 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1584628|ensemblbacteria:AAC65402|ensemblbacteria:AGN75609 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83429_trepa(display_long)|uniprotkb:TP_0414(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597272|imex:IM-9152-1661 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR001463("Sodium:alanine symporter")|ensemblbacteria:AAC65402(transcript)|ensemblbacteria:AGN75609(transcript)|ensemblbacteria:TP_0414(gene)|ensemblbacteria:TPANIC_0414(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015655"("alanine:sodium symporter activity")|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881862.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0414; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:sMlFdWAkjglgnHCFAkTeld2vd4A243276 intact-crc:39AD5CE834FD1099|rigid:3CboSA1ut/yTVmldzA2uBoHHlRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83635 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1597282|ensemblbacteria:AAC65599 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:sbcc_trepa(display_long)|uniprotkb:sbcC(gene name)|psi-mi:sbcC(display_short)|uniprotkb:TP_0627(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597278|imex:IM-9152-1662 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004592(Exonuclease SbcC)|interpro:IPR027417|refseq:WP_010882073.1|interpro:IPR038729|ensemblbacteria:AAC65599(transcript)|ensemblbacteria:TP_0627(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006260"(DNA replication) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0627; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:VRjmlkCkzhqxYjvxaDrgr8fwc38243276 intact-crc:BB2D7CB162E6CECD|rigid:c/5TU76+XKVxb7gLgElNqkHynMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83635 uniprotkb:O83958 intact:EBI-1597282|ensemblbacteria:AAC65599 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:sbcc_trepa(display_long)|uniprotkb:sbcC(gene name)|psi-mi:sbcC(display_short)|uniprotkb:TP_0627(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597289|imex:IM-9152-1663 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004592(Exonuclease SbcC)|interpro:IPR027417|refseq:WP_010882073.1|interpro:IPR038729|ensemblbacteria:AAC65599(transcript)|ensemblbacteria:TP_0627(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006260"(DNA replication) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0627; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VRjmlkCkzhqxYjvxaDrgr8fwc38243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:C02D3D8BF55C75F9|rigid:uupeieqKMoosewOCIlEsgyx3fzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83734 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1597299|ensemblbacteria:AAC65730 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y753_trepa(display_long)|uniprotkb:TP_0753(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597304|imex:IM-9152-1665 author score:0.537203825 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 refseq:WP_010882198.1|ensemblbacteria:AAC65730(transcript)|ensemblbacteria:TP_0753(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0753; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:CnBWT6Xu0mbqNVXrXmasEQ2ttMc243276 intact-crc:1028C369E226A4E6|rigid:Jpu8F3N8xRi7gw/A5uyLqidLrFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83734 uniprotkb:O83572 intact:EBI-1597299|ensemblbacteria:AAC65730 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:y753_trepa(display_long)|uniprotkb:TP_0753(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597295|imex:IM-9152-1664 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882198.1|ensemblbacteria:AAC65730(transcript)|ensemblbacteria:TP_0753(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0753; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CnBWT6Xu0mbqNVXrXmasEQ2ttMc243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:2716ADF493E53DC8|rigid:g9nUwTP4Ma8kEyT/GcU+x8k2vRM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83817 uniprotkb:O83970 intact:EBI-1597310|ensemblbacteria:AAC65813 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y845_trepa(display_long)|uniprotkb:TP_0845(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597313|imex:IM-9152-1666 author score:0.570453887 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003791(Protein of unknown function DUF188)|ensemblbacteria:AAC65813(transcript)|ensemblbacteria:TP_0845(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0845; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yjYuBeF+zkix/Gjfpcn+KolRGVM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:895BFFEB3140E488|rigid:VYqEoScvSHDZ2VWE0iN//+fI7tA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83475 uniprotkb:O83899 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597334|imex:IM-9152-1669 author score:0.531241232 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:93C96E0762435F5D|rigid:s9UZHEJfMIl8RuSqcs+Xj2GNeGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83817 uniprotkb:O83954 intact:EBI-1597310|ensemblbacteria:AAC65813 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y845_trepa(display_long)|uniprotkb:TP_0845(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597319|imex:IM-9152-1667 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003791(Protein of unknown function DUF188)|ensemblbacteria:AAC65813(transcript)|ensemblbacteria:TP_0845(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0845; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yjYuBeF+zkix/Gjfpcn+KolRGVM243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4D9656FBC0E6B417|rigid:T3MK+SkslZWR38xZQCvZbhbWd3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83137 uniprotkb:O83899 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597325|imex:IM-9152-1668 author score:0.564572454 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0099|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:4DB7C708E31803ED|rigid:oIak7zs8ce/lWt03IoPu4vAPVw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83899 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597346|imex:IM-9152-1671 author score:0.484172939 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:B15419253A4C19DF|rigid:dANQX9VF4uuMFprdaLXRPZ2Axfw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83261 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597340|imex:IM-9152-1670 author score:0.497628906 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:3498037995B6DE77|rigid:YWeDF9ji3xJyB8YDjAYd3BLf7W8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83899 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597358|imex:IM-9152-1673 author score:0.300675932 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:ADCB17C16AE891BD|rigid:xT8yXQMC6kZTSorXO6r0CjibLC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83899 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597352|imex:IM-9152-1672 author score:0.424181352 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:A30D41C70FC78D82|rigid:4kLeh4z0eSZhr9rzBNMkMt3M82s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83305 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597370|imex:IM-9152-1675 author score:0.200602862 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:03DBC430A54BDEE8|rigid:mhTUtdcJdZaHh+ilTwg8hpdKeyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83463 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597364|imex:IM-9152-1674 author score:0.262592252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:EB589BB0556A8410|rigid:ZBuNL9PZGHU2NNUGxuksTRuqP8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83899 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597376|imex:IM-9152-1676 author score:0.196320315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:1C8007AAE1108BD5|rigid:WsLA/l3P9ThZjKCJor/2IC53na0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83099 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597388|imex:IM-9152-1678 author score:0.146859815 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:45260DF788ECA876|rigid:VosdMJJ3pfyaOMmvijNpNfc8chI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83899 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597382|imex:IM-9152-1677 author score:0.175945036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:1A109D3933E30816|rigid:aWhZWBCrLl81FawZdnkWAYgN0zk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83899 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597394|imex:IM-9152-1679 author score:0.143518612 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:E927CCC94931180D|rigid:AgDXYFBnNGIDEgkVCjVrYlBi2G0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83899 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597400|imex:IM-9152-1680 author score:0.127752296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:19EA6B4926862C5A|rigid:0qN4mKzQcUokkZ2bwn4ikV8GkWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83899 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597418|imex:IM-9152-1683 author score:0.061303543 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:A1F6F47A6EBB8298|rigid:6FNmxyJmbqIumaHNiA1cGuUJGtQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83899 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597406|imex:IM-9152-1681 author score:0.103096528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:E85AFA783D75BBFD|rigid:FuD9/yJZLp3TjETwx7CXRvc2C6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83877 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597412|imex:IM-9152-1682 author score:0.0678013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:020283D7F309E111|rigid:vqthlEUKCJATdhxUz8OY7DVK078 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83767 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597424|imex:IM-9152-1684 author score:0.038669797 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:DD95EFD1833F4B6D|rigid:fg6nwYqpU77Lly3njFPrtRi+bM8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83282 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597430|imex:IM-9152-1685 author score:0.013163187 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:DF0D97BAE8BCE8F9|rigid:6QX5C2T9mATV/nc45wEbvTRx7gE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83899 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1597329|ensemblbacteria:AAC65888 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597436|imex:IM-9152-1686 author score:0.010926929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 intact-crc:EE80B1E6DD511DCC|rigid:O++oUhfBzvGIWqRlsFKCy7pAnnQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83899 uniprotkb:O83958 intact:EBI-1597329|ensemblbacteria:AAC65888 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y929_trepa(display_long)|uniprotkb:TP_0929(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597442|imex:IM-9152-1687 author score:0.000653576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65888(transcript)|ensemblbacteria:TP_0929(gene)|refseq:WP_010882372.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0929; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HEQFQEzM6qnVD3sL6YAuSL1vwfE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:E88780E8E343D62C|rigid:FeAIQUI0t1z0Y9ntwDgzHIejaZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83167 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597465|imex:IM-9152-1690 author score:0.088177508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 intact-crc:747F57FB9872C30F|rigid:+FAvLHfcwJxXqsXNATUDXfNzn28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83167 uniprotkb:O83738 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597451|imex:IM-9152-1688 author score:0.561798472 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:048E7912E21A3CAF|rigid:+1acIrddqdMyWDO84ObOy4uWFIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83167 uniprotkb:O83531 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597459|imex:IM-9152-1689 author score:0.339191351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:2B5ACAF002533C2A|rigid:ror83chfAfCSiufeOb/DAM3uR60 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83167 uniprotkb:O83954 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597477|imex:IM-9152-1692 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:209294722545F01C|rigid:1hfmJ3M9A8jehZptcL9v7XEANe8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83167 uniprotkb:O83745 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597471|imex:IM-9152-1691 author score:0.074154903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:DEBF668CAA7560E3|rigid:wrq1VtEInmTuDZD4hLk1bFPGq/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83949 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1597493|ensemblbacteria:AAC65938 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597489|imex:IM-9152-1694 author score:0.557306914 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 intact-crc:DF68D5AAB0D89D45|rigid:KP03tF5SvVcivnnNWEYzUX3Na/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83167 uniprotkb:O83958 intact:EBI-1597448|ensemblbacteria:AAC65122|ensemblbacteria:AGN75352 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83167_trepa(display_long)|uniprotkb:TP_0130(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597483|imex:IM-9152-1693 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881579.1|ensemblbacteria:AAC65122(transcript)|ensemblbacteria:AGN75352(transcript)|ensemblbacteria:TP_0130(gene)|ensemblbacteria:TPANIC_0130(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0130; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jF7oSGa+05tRQA2I3mTARe7qos243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B9C42F59D60811A0|rigid:S/6eD40wlaUyPwu1BoEtWhybEhw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83949 uniprotkb:O83099 intact:EBI-1597493|ensemblbacteria:AAC65938 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597511|imex:IM-9152-1697 author score:0.243626594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:02350153D5AABE35|rigid:Pb8ghcX0BgBUmSAjcLCVrte39MQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83949 uniprotkb:O83982 intact:EBI-1597493|ensemblbacteria:AAC65938 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597499|imex:IM-9152-1695 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:A6123C9D7206AE25|rigid:KFp/UwZxYsLJOnB5q29+RzYvSR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83949 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1597493|ensemblbacteria:AAC65938 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597505|imex:IM-9152-1696 author score:0.248621847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 intact-crc:96BE1FBB69B180BE|rigid:Oryt//b7qQJLztSBZeSF7C7Vhhk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83949 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1597493|ensemblbacteria:AAC65938 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597517|imex:IM-9152-1698 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 intact-crc:AF3EBAC2AA99E352|rigid:3egKen9IZ7TNQiKAIvP3WmHhrKk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83949 uniprotkb:O83877 intact:EBI-1597493|ensemblbacteria:AAC65938 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597523|imex:IM-9152-1699 author score:0.119790274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:F3637EA4B5B9BB15|rigid:T8l7aGTdVgjvAnD1TxyaKhUwg/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83949 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1597493|ensemblbacteria:AAC65938 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597529|imex:IM-9152-1700 author score:0.108892141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 intact-crc:2ADE0996C14E1F55|rigid:8fGTfR4J2mYn00dTa7ZR2EKxZ6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83949 uniprotkb:O83282 intact:EBI-1597493|ensemblbacteria:AAC65938 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597535|imex:IM-9152-1701 author score:0.024350912 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:1AB5DFC2D5D39F2C|rigid:aQxhoRfnRp4Ae1b/hC1eZ22k7yo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83949 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1597493|ensemblbacteria:AAC65938 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597547|imex:IM-9152-1703 author score:0.001562202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 intact-crc:10C0FC6B9D81C267|rigid:Zt4wBVlAW3jrRyigaBeWswsG8Gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83949 uniprotkb:O83954 intact:EBI-1597493|ensemblbacteria:AAC65938 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:htpg_trepa(display_long)|uniprotkb:htpG(gene name)|psi-mi:htpG(display_short)|uniprotkb:High temperature protein G(gene name synonym)|uniprotkb:TP_0984(locus name)|uniprotkb:Heat shock protein HtpG(gene name synonym) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597541|imex:IM-9152-1702 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|refseq:WP_010882428.1|ensemblbacteria:AAC65938(transcript)|ensemblbacteria:TP_0984(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR036890|interpro:IPR037196 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0984; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tjCqGx4uXajOQwdvBjqz430ntMk243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:3FE0EFDFAE167654|rigid:B0SEcU2g9DaN8hEfbnMbEsIpydE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83227 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597559|imex:IM-9152-1705 author score:0.156878757 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0197; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:322D30552D140BAC|rigid:A84Z+m/yUu8AE6JaiAljOiPrEMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83532 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597565|imex:IM-9152-1706 author score:0.555965394 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:551F29CA2089073B|rigid:MbyV26CY1NSr5nKIu3ePgQzeM+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83227 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597553|imex:IM-9152-1704 author score:0.55721289 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0197; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:C1A0B9CCF585400B|rigid:WCpzK3I+htuJGLKnhXiw8ytEg5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83132 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597575|imex:IM-9152-1707 author score:0.506883309 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:441F95C5A7CA090D|rigid:BwQlflu3y7LP/GtPf/hJGyZp6ho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83310 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1588258|ensemblbacteria:AAC65268 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597593|imex:IM-9152-1710 author score:0.493224433 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 intact-crc:3979EBCFB3A951BE|rigid:glT75x0HyoJEYC5AGNz9/m8B5sw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83478 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597581|imex:IM-9152-1708 author score:0.506684858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 intact-crc:2F0B0384645913FB|rigid:Rq3OS2qou0pu71aenmg8zCwhS8o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83890 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1583720|ensemblbacteria:AAC65878 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:y920_trepa(display_long)|uniprotkb:TP_0920(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597587|imex:IM-9152-1709 author score:0.506684858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:TP_0920(gene)|ensemblbacteria:AAC65878(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0920|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:Q+H3nbqL+zZ0Gmxo/shYT8e9QoI243276 intact-crc:B619707445A9E49F|rigid:kd9OoqkL+xGC4McmIDXDZY6z2Cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83132 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597599|imex:IM-9152-1711 author score:0.466352473 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:139CFFFF79FEE867|rigid:v5WZjknahr/OuL/upHw8rtavi1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83275 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597605|imex:IM-9152-1712 author score:0.41988362 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:C196C08947B4B31D|rigid:zLhHrjoCsF6bkzEScRxnMyW4FYo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83098 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597611|imex:IM-9152-1713 author score:0.413340315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:104F2161500DA7B4|rigid:T0c7B6X2ve+8ZJDvQOjAMmK4bEQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83311 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597617|imex:IM-9152-1714 author score:0.3747931 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:A01A5A754C78EF03|rigid:9F7ktNJDH/myHLFCMEIStwu3mKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83132 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597623|imex:IM-9152-1715 author score:0.356066965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:3CFAC19516CEE423|rigid:vtB2gR4aMINqikPRQr3XMABnLQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83132 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597629|imex:IM-9152-1716 author score:0.337770981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:98727FD9A43DFC6A|rigid:sr52ejmy+ASxALXjHmG12cuZS+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83132 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597641|imex:IM-9152-1718 author score:0.192452827 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:1B0D2EBBCCA4C34B|rigid:ebuBtqswO9EoYqprn89wWYjgMKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83670 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597635|imex:IM-9152-1717 author score:0.331775463 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:B842B29A94F69742|rigid:RWU3YbZPmMO16gv0w6Sp8C2Sxwc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83132 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597653|imex:IM-9152-1720 author score:0.177297932 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:E9ADCB945E2F13AB|rigid:5XtjkkM8EtC17GXRgs6hY9W+K48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83305 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597647|imex:IM-9152-1719 author score:0.18125911 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:38F1D991811C0060|rigid:1ej0o4bDGt716vpXNMWBY3yf+34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83132 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597659|imex:IM-9152-1721 author score:0.177297932 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:062A8FEFFD99ABEA|rigid:ToACZqqAoY+Gjf6twhpOfw63ofQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83132 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597665|imex:IM-9152-1722 author score:0.092072191 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:6C5E9C211DC5ECCB|rigid:ec+CZmbxlXeg43yjwq/sgXWCd6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83413 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597677|imex:IM-9152-1724 author score:0.054476779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:86C05F56E73DC54C|rigid:cvVJZl1u2a1vvajT86rOulWBBx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83132 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597671|imex:IM-9152-1723 author score:0.083061854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:47175D46A74D2F0D|rigid:VvctSJAeoarj/AqbYiZH6TPk+i4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83132 uniprotkb:O83282 intact:EBI-1597569|ensemblbacteria:AAC65090 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597683|imex:IM-9152-1725 author score:0.01163091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:C1514F2FCC1943B9|rigid:TBjdDorjgJDP75ZXKrwjkDVr2cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83132 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597695|imex:IM-9152-1727 author score:0.000576645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:098E118D6A6EAF1D|rigid:X0oNMa2vzwGLbGQ88wOcKjm/FF0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83132 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1597569|ensemblbacteria:AAC65090 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:ptas_trepa(display_long)|uniprotkb:pta(gene name)|psi-mi:pta(display_short)|uniprotkb:Phosphotransacetylase(gene name synonym)|uniprotkb:TP_0094(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597689|imex:IM-9152-1726 author score:0.00965242 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR012147(Phosphate acetyl/butyryltransferase)|interpro:IPR004614(Phosphate acetyltransferase)|interpro:IPR002505(Phosphate acetyl/butaryl transferase)|refseq:WP_010881543.1|ensemblbacteria:AAC65090(transcript)|ensemblbacteria:TP_0094(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0008959"(phosphate acetyltransferase activity)|interpro:IPR042112|interpro:IPR042113 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0094; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:16F/eiF0xjRGXnDbCh4aVmA6KH0243276 intact-crc:D82985931512A719|rigid:m1G7+nRV5OFgf7jyHNkHT0qNbOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83659 uniprotkb:O83572 intact:EBI-1597701|ensemblbacteria:AAC65628|ensemblbacteria:AGN75832 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:o83659_trepa(display_long)|uniprotkb:TP_0653(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597704|imex:IM-9152-1728 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_010882098.1|ensemblbacteria:AAC65628(transcript)|ensemblbacteria:AGN75832(transcript)|ensemblbacteria:TP_0653(gene)|ensemblbacteria:TPANIC_0653(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR035906 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0653; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vEtsIErdVg3MTJOvtZsNzJ+2JeE243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:A82B37819951B8BC|rigid:4uzeLW2dQg2nJurH5TqyKkyFvE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83659 uniprotkb:O83413 intact:EBI-1597701|ensemblbacteria:AAC65628|ensemblbacteria:AGN75832 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83659_trepa(display_long)|uniprotkb:TP_0653(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597710|imex:IM-9152-1729 author score:0.159289405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_010882098.1|ensemblbacteria:AAC65628(transcript)|ensemblbacteria:AGN75832(transcript)|ensemblbacteria:TP_0653(gene)|ensemblbacteria:TPANIC_0653(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR035906 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0653; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vEtsIErdVg3MTJOvtZsNzJ+2JeE243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:F57C53C671A10B62|rigid:qb9ijpaULmd4J38NxBVDnq6/EBs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83659 uniprotkb:O83958 intact:EBI-1597701|ensemblbacteria:AAC65628|ensemblbacteria:AGN75832 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83659_trepa(display_long)|uniprotkb:TP_0653(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597716|imex:IM-9152-1730 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:WP_010882098.1|ensemblbacteria:AAC65628(transcript)|ensemblbacteria:AGN75832(transcript)|ensemblbacteria:TP_0653(gene)|ensemblbacteria:TPANIC_0653(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR035906 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0653; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vEtsIErdVg3MTJOvtZsNzJ+2JeE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:08EAB9913EAA77F1|rigid:TEMEv/kE1UC6zEL92gHJhPbXrx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83735 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1597726|ensemblbacteria:AAC65721 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:miab_trepa(display_long)|uniprotkb:miaB(gene name)|psi-mi:miaB(display_short)|uniprotkb:"tRNA-i(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0754(locus name)|uniprotkb:"(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597722|imex:IM-9152-1731 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006463("tRNA-i(6)A37 modification enzyme MiaB")|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR038135|refseq:WP_010882199.1|ensemblbacteria:AAC65721(transcript)|ensemblbacteria:TP_0754(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0035596"(methylthiotransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0754; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:iAjpdU4FJ8PId77+Ppv9eJVRJ4c243276 intact-crc:D03AE957494D973E|rigid:wyC/jmJC73VK43J8jCyJsOcRlWg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83735 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1597726|ensemblbacteria:AAC65721 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:miab_trepa(display_long)|uniprotkb:miaB(gene name)|psi-mi:miaB(display_short)|uniprotkb:"tRNA-i(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0754(locus name)|uniprotkb:"(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597731|imex:IM-9152-1732 author score:0.339080801 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006463("tRNA-i(6)A37 modification enzyme MiaB")|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR038135|refseq:WP_010882199.1|ensemblbacteria:AAC65721(transcript)|ensemblbacteria:TP_0754(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0035596"(methylthiotransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0754; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:iAjpdU4FJ8PId77+Ppv9eJVRJ4c243276 intact-crc:CCD9F6088492F744|rigid:+a4C1U7W4/Tif0RRXhIcF5z99Sw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83768 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1597747|ensemblbacteria:AAC65764 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y789_trepa(display_long)|uniprotkb:TP_0789(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597752|imex:IM-9152-1735 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR033399|refseq:WP_010882234.1|ensemblbacteria:AAC65764(transcript)|ensemblbacteria:TP_0789(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0789; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:e6/nLcXi5GIJ3rviTNpC03K0baU243276 intact-crc:F338EE08682FB39F|rigid:TXbYSiDIgqRmYwKh+PRG+27N72I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83768 uniprotkb:O83970 intact:EBI-1597747|ensemblbacteria:AAC65764 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y789_trepa(display_long)|uniprotkb:TP_0789(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597743|imex:IM-9152-1734 author score:0.55503821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033399|refseq:WP_010882234.1|ensemblbacteria:AAC65764(transcript)|ensemblbacteria:TP_0789(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0789; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e6/nLcXi5GIJ3rviTNpC03K0baU243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:A41B0EB7A9534BDD|rigid:/mafAI40MEWXkDohFxy2g2Mjw2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83735 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1597726|ensemblbacteria:AAC65721 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:miab_trepa(display_long)|uniprotkb:miaB(gene name)|psi-mi:miaB(display_short)|uniprotkb:"tRNA-i(6)A37 methylthiotransferase"(gene name synonym)|uniprotkb:TP_0754(locus name)|uniprotkb:"(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597737|imex:IM-9152-1733 author score:0.003230313 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR020612|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR006463("tRNA-i(6)A37 modification enzyme MiaB")|interpro:IPR007197(Radical SAM)|interpro:IPR023404|interpro:IPR038135|refseq:WP_010882199.1|ensemblbacteria:AAC65721(transcript)|ensemblbacteria:TP_0754(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0035596"(methylthiotransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0754; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:iAjpdU4FJ8PId77+Ppv9eJVRJ4c243276 intact-crc:602039A9A49ABA28|rigid:pW0WMrVxdWXVt+FaIyKpbsylWaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83527 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1581703|ensemblbacteria:AAC65502 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597764|imex:IM-9152-1737 author score:0.553471022 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 intact-crc:09862899E36B7193|rigid:WilFGdSPQJHXleDf0ZzcNtCA3iw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83768 uniprotkb:O83958 intact:EBI-1597747|ensemblbacteria:AAC65764 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y789_trepa(display_long)|uniprotkb:TP_0789(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597758|imex:IM-9152-1736 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033399|refseq:WP_010882234.1|ensemblbacteria:AAC65764(transcript)|ensemblbacteria:TP_0789(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0789; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e6/nLcXi5GIJ3rviTNpC03K0baU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:2C5FEEF8A630087D|rigid:cJRnZtgsqTR7HczpMurBkGQJazM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83119 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597770|imex:IM-9152-1738 author score:0.51328943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:31E9ACBFED26D0FA|rigid:p/jctkNxMsS4ceGSdP/hf9HS87w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83805 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597776|imex:IM-9152-1739 author score:0.499831323 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:E23EE2EFDAF02D6A|rigid:qbmCaIKiZFsCaTjCJZ+D96QO8cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83805 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597788|imex:IM-9152-1741 author score:0.426334568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:51791C86A69A7773|rigid:RithtnxF5iKtluCcC/OFHVZznWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83068 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597782|imex:IM-9152-1740 author score:0.493101142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:66FB93B60FD621B0|rigid:prsSejvTgQMa9rEEIwvrAsJFXfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83805 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597806|imex:IM-9152-1744 author score:0.381006278 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:2BDAEFC40EE5D7DA|rigid:6XkC0OXrpC5P/43OYPDXJPUcXcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83239 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597794|imex:IM-9152-1742 author score:0.419763476 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 intact-crc:53FE639E57266743|rigid:JB+M+HiSklg+B1YqLDbuZDJAYrc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83459 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597800|imex:IM-9152-1743 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:FDFABA0E5B2B23A9|rigid:ybI+7+iK//cSExzRcpiwZJAAxyU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83805 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597812|imex:IM-9152-1745 author score:0.374677525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:CC13485D89A32612|rigid:g/+U/svuaRmEUab2nrETh6yaJEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83805 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597818|imex:IM-9152-1746 author score:0.374677525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:E4E75DEAFDFEC937|rigid:Jl9RXirenVuG7GBObkaAQOhAPXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83805 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597824|imex:IM-9152-1747 author score:0.302531602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:3DA1E2977084592E|rigid:axZ+J1vs019OplbX7Vw80nVoqFw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:P21992 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597842|imex:IM-9152-1750 author score:0.151393502 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:68EA150CE6004A86|rigid:k6VsP+63Qf5S/OyeMvn0O6OegrM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83463 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597830|imex:IM-9152-1748 author score:0.274903655 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:C2C711DB910D01BD|rigid:lW6CzcnvPqcEEjX1vIQs8bwXO44 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83805 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597836|imex:IM-9152-1749 author score:0.154884883 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:3808EEC2C9913E28|rigid:bk3QgjEuYGzcOEq6Z3O2JHUUJc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83805 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597854|imex:IM-9152-1752 author score:0.06500969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:2DC2EEBDC56820B8|rigid:xhr2xOaaY0NuGm9o4zXI2W+un1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83574 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597848|imex:IM-9152-1751 author score:0.109035814 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:ABFD5CF9927CD692|rigid:CQHxa/atDxnqMQEDo9DGgmgxhFg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83805 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597860|imex:IM-9152-2098 author score:0.060269483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:C1EA468A697B94CA|rigid:G0Q+eOn+2gZ2UCofhStUDHboIKY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83805 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597866|imex:IM-9152-2099 author score:0.04106747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:5A9A232F0B4680C9|rigid:FPdk8JJaH4XuNJ9iOZC1ED3f0sk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83238 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1585669|ensemblbacteria:AAC65198 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83238_trepa(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TP_0208(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597878|imex:IM-9152-2101 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|ensemblbacteria:AAC65198(transcript)|ensemblbacteria:TP_0208(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|refseq:WP_010881656.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0208; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:lEmXcpm7ehHfYtWFoAIjCA8/aYA243276 intact-crc:B650A2CF35B625D3|rigid:vBbiCBFDDRLro1ai2L1SHUQ9MsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83958 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597872|imex:IM-9152-2100 author score:0.000695806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0833; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:0AB647823E48787B|rigid:RIvDtQA8L6uFfChHhJ8+kklAoJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83396 uniprotkb:O83887 intact:EBI-1597894|ensemblbacteria:AAC65382 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:y381_trepa(display_long)|uniprotkb:TP_0381(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597890|imex:IM-9152-2103 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011737(Conserved hypothetical protein CHP02206, TP0381)|refseq:WP_010881829.1|ensemblbacteria:AAC65382(transcript)|ensemblbacteria:TP_0381(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0381; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LTrGl4YpLhr37hayLB/PadKYrvY243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:391C60B705F8327A|rigid:Xm4AEbmLDwPKgl17AyQaYin3A3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83324 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1586228|ensemblbacteria:AAC65290|ensemblbacteria:AGN75506 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:rfud_trepa(display_long)|uniprotkb:rfuD(gene name)|psi-mi:rfuD(display_short)|uniprotkb:TPANIC_0302(orf name)|uniprotkb:TP_0302(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597884|imex:IM-9152-2102 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR001851(Bacterial inner-membrane translocator)|ensemblbacteria:AAC65290(transcript)|ensemblbacteria:AGN75506(transcript)|ensemblbacteria:TP_0302(gene)|ensemblbacteria:TPANIC_0302(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|refseq:WP_010881751.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0302; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:FIaKRVgLj4PQ9+o2zpdqvaCRogM243276 intact-crc:31C4161792F60A2A|rigid:DKhfKCDmQj0B16HchhtkYPgB/IQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83548 uniprotkb:O83887 intact:EBI-1597899|ensemblbacteria:AAC65522 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:tpis_trepa(display_long)|uniprotkb:tpiA(gene name)|psi-mi:tpiA(display_short)|uniprotkb:tpi(gene name synonym)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TP_0537(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597903|imex:IM-9152-2104 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022896|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR020861|refseq:WP_010881984.1|ensemblbacteria:AAC65522(transcript)|ensemblbacteria:TP_0537(gene)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|interpro:IPR035990 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0537; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LouVci1Br1otHfdSIYJy1MBVcRs243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:767AD141435F583C|rigid:nEdPq+GRrUtYC0HG3P3PVF2K0cU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83677 uniprotkb:O83887 intact:EBI-1597909|ensemblbacteria:AAC26569|ensemblbacteria:AGN75849 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83677_trepa(display_long)|uniprotkb:TP_0671(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597912|imex:IM-9152-2105 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|ensemblbacteria:AAC26569(transcript)|ensemblbacteria:AGN75849(transcript)|ensemblbacteria:TP_0671(gene)|ensemblbacteria:TPANIC_0671(gene)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016780"(phosphotransferase activity, for other substituted phosphate groups) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0671; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HprFrwHI3QTQOoOgim0OVGwt2uc243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:3D5BF18B61CE18FD|rigid:/fMuQLga0U20f0ciiWxql7QxtfE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83744 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1585682|ensemblbacteria:AAC65734 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:y763_trepa(display_long)|uniprotkb:TP_0763(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597918|imex:IM-9152-2106 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 ensemblbacteria:AAC65734(transcript)|ensemblbacteria:TP_0763(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0763; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:92wDQngr5kpfX9RmKyfjPh9uS2w243276 intact-crc:3658246B8D67A805|rigid:er2Drukn4XUSuIswymzr+JjPtaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83947 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1594449|ensemblbacteria:AAC65937|ensemblbacteria:AGN76146 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:o83947_trepa(display_long)|uniprotkb:TP_0982(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597924|imex:IM-9152-2107 author score:0.552739481 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR022764|ensemblbacteria:AAC65937(transcript)|ensemblbacteria:AGN76146(transcript)|ensemblbacteria:TP_0982(gene)|ensemblbacteria:TPANIC_0982(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882426.1|interpro:IPR035952 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0982; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:aJ+DcXEG2pmndVqR+BuWAv1zt7c243276 intact-crc:8DCBB31F47AB8805|rigid:gyJJeiD44/e5CFyEu4UMIJFyGEw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08399 uniprotkb:O83505 intact:EBI-1585657|ensemblbacteria:AAC65954 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:gyrb_trepa(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:TP_1006(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597930|imex:IM-9152-2108 author score:0.551125747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|ensemblbacteria:AAC65954(transcript)|go:"GO:0006265"(DNA topological change)|ensemblbacteria:TP_1006(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|refseq:WP_010882450.1|interpro:IPR034160|interpro:IPR036890 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_1006|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OkQQ4SjHW9+OzASF/QiIYqo75Lg243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:B74D797A358B5AD2|rigid:K0MS2/Pww+TiTk2rdAux+Yrk6as false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83654 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597936|imex:IM-9152-2109 author score:0.51117083 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0648|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:A5E13D93CA8B9E53|rigid:EI7fjms7LlfRVmzAuX9H6vkjIVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:P27771 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1593360|uniprotkb:O83775|ensemblbacteria:AAC65760 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:p5cr_trepa(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:TP_0797(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597948|imex:IM-9152-2111 author score:0.474871675 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|ensemblbacteria:AAC65760(transcript)|ensemblbacteria:TP_0797(gene)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010882242.1|interpro:IPR029036|interpro:IPR036291 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0797|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:nzwapTm7KjLpf0btHIa+PzwyOK4243276 intact-crc:567493215B9D942A|rigid:yKyfpwIeNVn2SjbbfXrl0roHTa4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83395 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597942|imex:IM-9152-2110 author score:0.474871675 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0380|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:58CED6309AA3BE1D|rigid:PSxvynPYURKi9nNBPlhQWecujqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83505 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597960|imex:IM-9152-2113 author score:0.430101987 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:03E6601781540876|rigid:ws7E3/nuNKVLqX/mAqU4BOqSL00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83133 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597954|imex:IM-9152-2112 author score:0.430851242 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:B403ACCC90C17420|rigid:Km3sGKv/aNtFYCLyoaBu/zzoBHQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96121 uniprotkb:O83505 intact:EBI-1597970|ensemblbacteria:AAC65158 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:gpma_trepa(display_long)|uniprotkb:gpmA(gene name)|psi-mi:gpmA(display_short)|uniprotkb:gpm(gene name synonym)|uniprotkb:pgm(gene name synonym)|uniprotkb:TP_0168(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597966|imex:IM-9152-2114 author score:0.422392 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|refseq:WP_010881615.1|go:"GO:0006096"(glycolytic process)|go:"GO:0046538"(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|ensemblbacteria:AAC65158(transcript)|ensemblbacteria:TP_0168(gene)|go:"GO:0006094"(gluconeogenesis)|interpro:IPR029033 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0168|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Oa6Fp1PMj8xavrV1twn2TxYwVhM243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:6E4EBE0A2F515656|rigid:aNW7bc0Z6+p2iy66528GnjLD1xw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83912 uniprotkb:O83505 intact:EBI-1597980|ensemblbacteria:AAC65901 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:y942_trepa(display_long)|uniprotkb:TP_0942(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597976|imex:IM-9152-2115 author score:0.422392 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882385.1|ensemblbacteria:AAC65901(transcript)|ensemblbacteria:TP_0942(gene)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036679 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0942|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5kOR2Iaqif1c+6KTNjFR7VGW9CE243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:A119F48C70071340|rigid:6Vnp3oGlIOi6JRowV5UpVMp5QqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83327 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198543|intact:EBI-1583552|ensemblbacteria:AAC65292 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:pyrg_trepa(display_long)|uniprotkb:pyrG(gene name)|psi-mi:pyrG(display_short)|uniprotkb:TP_0305(locus name)|uniprotkb:UTP--ammonia ligase(gene name synonym)|uniprotkb:Cytidine 5'-triphosphate synthase(gene name synonym)|uniprotkb:Cytidine triphosphate synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597985|imex:IM-9152-2116 author score:0.402819925 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR033828|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|refseq:WP_010881754.1|ensemblbacteria:AAC65292(transcript)|ensemblbacteria:TP_0305(gene)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0305|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:APACO59bBWxloqEuy3KSnF0gPp8243276 intact-crc:0A41BF368A11E0E2|rigid:7lVcP8SXrOR1RUgsDTZBPC7JRJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83847 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198567|intact:EBI-1583350|ensemblbacteria:AAC65840|ensemblbacteria:AGN76046 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83847_trepa(display_long)|uniprotkb:TP_0877(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597991|imex:IM-9152-2117 author score:0.402819925 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR037522|refseq:WP_010882320.1|ensemblbacteria:AAC65840(transcript)|ensemblbacteria:AGN76046(transcript)|ensemblbacteria:TP_0877(gene)|ensemblbacteria:TPANIC_0877(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0877|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:+QpyFXrHDZlRcsvImMZ76wZft48243276 intact-crc:A421507C56C48638|rigid:p1W3DN4zjoDx8U3tTFbM/UsLD64 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83732 uniprotkb:O83505 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1597997|imex:IM-9152-2118 author score:0.383552535 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:175CF9251F7FBA5E|rigid:xzPFE4+9pHO9uj79fIq2d668/aE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83126 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198532|intact:EBI-1583164|ensemblbacteria:AAC65083|ensemblbacteria:AGN75307 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83126_trepa(display_long)|uniprotkb:TP_0088(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598003|imex:IM-9152-2119 author score:0.377207262 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 refseq:WP_010881537.1|ensemblbacteria:AAC65083(transcript)|ensemblbacteria:AGN75307(transcript)|ensemblbacteria:TP_0088(gene)|ensemblbacteria:TPANIC_0088(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0088|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:aL81GOgbO9MHAhIsf+BwaII/JUs243276 intact-crc:19DCEBFBC3584011|rigid:uVslQR8hXniTjvJeEpfoxxIXWMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83130 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598009|imex:IM-9152-2120 author score:0.364644001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:6C83692CDE3C8E19|rigid:d5haewoGaeKIb2bhhPTE1nhKETs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83105 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598015|imex:IM-9152-2121 author score:0.358429657 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:8B5D1AAB299C8D42|rigid:14lk2oYHeiAim9fIcSZtFXQzowg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83195 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198300|intact:EBI-1581790|ensemblbacteria:AAC65149 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:syp_trepa(display_long)|uniprotkb:proS(gene name)|psi-mi:proS(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0160(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598021|imex:IM-9152-2122 author score:0.334060589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004500(Prolyl-tRNA synthetase, class IIa, bacterial)|interpro:IPR023717|interpro:IPR007214(YbaK/aminoacyl-tRNA synthetase associated region)|interpro:IPR033730|ensemblbacteria:AAC65149(transcript)|ensemblbacteria:TP_0160(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR036621|interpro:IPR036754|interpro:IPR044140 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0160|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:KgWsHUocIl6BMMEJXcLve8R0juA243276 intact-crc:89A192B1AD6E4486|rigid:JumOxAmWLcW4NXnhzBqgyrZUadc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83505 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598027|imex:IM-9152-2123 author score:0.334060589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:DC6BFAD21AA6B2A1|rigid:WzaJvzlP/VasMoN/J0ugrk5oje0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83068 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598033|imex:IM-9152-2124 author score:0.328098301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:0DBFBC31B7F9227A|rigid:wZ1Bnx1DexksUXES13q/M5YKWv4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83505 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598039|imex:IM-9152-2125 author score:0.250919657 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:9DD2197881A0296B|rigid:vi6KmE8ahFFWXT0yPZwdA90q1i8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83804 uniprotkb:O83505 intact:EBI-1581690|ensemblbacteria:AAC65801|ensemblbacteria:AGN76002 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83804_trepa(display_long)|uniprotkb:TP_0832(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598051|imex:IM-9152-2127 author score:0.217180935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019606|interpro:IPR016862(Uncharacterised conserved protein UCP027936)|ensemblbacteria:AAC65801(transcript)|ensemblbacteria:AGN76002(transcript)|ensemblbacteria:TP_0832(gene)|ensemblbacteria:TPANIC_0832(gene)|refseq:WP_010882276.1 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0832|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AkP7ORlA0IEHgdxrigirL3nlO+w243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:4BCC7C0E72F19604|rigid:kVt7EK1owyOs95RBuuDkNEthYls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83505 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598045|imex:IM-9152-2126 author score:0.231225662 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:9E094E097A0EAEFB|rigid:BxTOAQtdls4r2vcbTDp1k34sRbE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83505 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598057|imex:IM-9152-2128 author score:0.086347549 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:DEC6D23E53C4897F|rigid:TAtmkKRmYOiulxYkZwr+f+2HApg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83927 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598063|imex:IM-9152-2129 author score:0.072592789 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:95B50C5E9C335EB2|rigid:FiUCVzBJNOksKTzMTMjfuTGDOqA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83877 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598069|imex:IM-9152-2130 author score:0.03741641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:193E01AFC1748AE9|rigid:4AipaZk9ZpihtMw+5gEe2nxePWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83413 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598075|imex:IM-9152-2131 author score:0.033725249 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:0938DF0F3D2CE549|rigid:fqA01YhhSm6qwvyu0qrtKuSh3zU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83667 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598081|imex:IM-9152-2132 author score:0.031190064 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:5E5B498CC5BABF83|rigid:w9rBqzM3EvK/ispEobfuzv2BhtM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83505 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598087|imex:IM-9152-2133 author score:0.021045343 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:DEE907C56381D4BA|rigid:PH0YmpMV1b/j8SyLYKxAvxoxPM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83745 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598093|imex:IM-9152-2134 author score:0.017493745 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:9F4BEFAA626BCD6E|rigid:dOZS3mHVelvSre3HUwonBuM+fBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83505 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598099|imex:IM-9152-2135 author score:0.007078233 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:138CB2D261918C37|rigid:SE78yL7B1IZlIdyKLNZcGlSBkuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83505 uniprotkb:O83954 intact:EBI-1587673|ensemblbacteria:AAC65479 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598105|imex:IM-9152-2136 author score:0.005869583 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:DFCB9DEA020A9097|rigid:CQ3ylrUO9U5vnGCPM8NvtdT93Uk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83505 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1587673|ensemblbacteria:AAC65479 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:dnag_trepa(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:TP_0492(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598111|imex:IM-9152-2137 author score:0.0003494 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR013264(DNA primase, catalytic core, N-terminal)|interpro:IPR006295(DNA primase, DnaG)|interpro:IPR006171(TOPRIM)|interpro:IPR002694(Zinc finger, CHC2-type)|ensemblbacteria:AAC65479(transcript)|ensemblbacteria:TP_0492(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:1990077"(primosome complex)|interpro:IPR030846|refseq:WP_010881941.1|interpro:IPR034151|interpro:IPR036977|interpro:IPR037068 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0492; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:cffTzAXol7sfoK1trqONZV6vrZg243276 intact-crc:E4878922BDDB66F9|rigid:njXaQL/JZZmKPxwnRzlEeUErdcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83142 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598120|imex:IM-9152-2138 author score:0.544257149 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:C9FDFAB1C2B73C72|rigid:F8WTE5wU62xQT8+0+MAQfs4RB1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83142 uniprotkb:O83572 intact:EBI-1598117|ensemblbacteria:AAC26552 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598126|imex:IM-9152-2139 author score:0.430407445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 intact-crc:BA959382892FFFB6|rigid:bAd21teYm7xecCG0QaSV7SPt3K4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83142 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598138|imex:IM-9152-2141 author score:0.306052744 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:F79D77E3B774FAC3|rigid:ANCNDh6yiTYGCMS8adOo8wX18BM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83887 uniprotkb:O83142 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598132|imex:IM-9152-2140 author score:0.397761405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:366F6428B6C0A52B|rigid:ur+6JCTHuHNucY4IkZJRkImnd8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83142 uniprotkb:O83982 intact:EBI-1598117|ensemblbacteria:AAC26552 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598144|imex:IM-9152-2142 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:CB2B239487B815A6|rigid:dTOlET/IZs6xoIG8+wPtq7mOXwY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83142 uniprotkb:O83531 intact:EBI-1598117|ensemblbacteria:AAC26552 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598150|imex:IM-9152-2143 author score:0.272857387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:1F501FC414AF2159|rigid:o7/dfZV7T4j20wF/rKjxOoSo5ME false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83142 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598156|imex:IM-9152-2144 author score:0.232267228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:FCEFA4D7610BCA03|rigid:YhYr3GB26dckU120zLRJfBKT/nw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83142 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598162|imex:IM-9152-2145 author score:0.113339703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:03E69503AC03320E|rigid:xE9GUqWijbREIlkjN8D4B/OchHc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83142 uniprotkb:O83954 intact:EBI-1598117|ensemblbacteria:AAC26552 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598174|imex:IM-9152-2147 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:3AC4BD3312A3A7EC|rigid:Xrnpjj8JBV33W811GG9hNHd/4/c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83142 uniprotkb:O83745 intact:EBI-1598117|ensemblbacteria:AAC26552 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598168|imex:IM-9152-2146 author score:0.077160036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:585504082B4ADC4D|rigid:K81dRUMQBLLnr0o3ScfAw7vFbDE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83142 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1598117|ensemblbacteria:AAC26552 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:5ntd_trepa(display_long)|uniprotkb:TP_0104(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598180|imex:IM-9152-2148 author score:0.001148091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006420(NAD pyrophosphatase/5-nucleotidase NadN)|refseq:WP_010881553.1|ensemblbacteria:AAC26552(transcript)|ensemblbacteria:TP_0104(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009166"(nucleotide catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029052|interpro:IPR036907 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0104; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:K3i0WV2FwmravJdZ61VXUYAJhgo243276 intact-crc:0001F162FF9A4072|rigid:8Ou2OoOqK5NEStWC7ddcq3BV/Yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83086 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598189|imex:IM-9152-2149 author score:0.54191072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:0278C004F7508AA2|rigid:SAi2qbvyZguYJ2onIAmDg1qG4/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27771 uniprotkb:O83086 intact:EBI-1593360|uniprotkb:O83775|ensemblbacteria:AAC65760 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:p5cr_trepa(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:TP_0797(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598195|imex:IM-9152-2150 author score:0.488821012 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|ensemblbacteria:AAC65760(transcript)|ensemblbacteria:TP_0797(gene)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010882242.1|interpro:IPR029036|interpro:IPR036291 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0797|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nzwapTm7KjLpf0btHIa+PzwyOK4243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:B9CC7C99D574D8DA|rigid:MRFRtIaVNXRF2UD5Pmu97m8O7Nc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83086 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598201|imex:IM-9152-2151 author score:0.435338337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:65CA7EB40BC1700F|rigid:IgXTUw6LVH97KQoqXlv85KWuFjI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83931 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598207|imex:IM-9152-2152 author score:0.428732183 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:5CE9D87CFD6B8697|rigid:YcFziSU6CVbefkrBPTcEQZoc0Ao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:Q08255 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598213|imex:IM-9152-2153 author score:0.422151331 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:47DEFD6C5642BF91|rigid:2INShH8z+mdebNSFJXVGKAAcQxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83086 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598219|imex:IM-9152-2154 author score:0.415598004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:F79E7FA93630E31A|rigid:kv4apI0GFuQ/7nMZgXcUmNNbV7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83596 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598231|imex:IM-9152-2156 author score:0.370673642 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:B588552963C60824|rigid:q+IQ64e5Eb2kWUSGJ2agtSi3PHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83542 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598225|imex:IM-9152-2155 author score:0.396124841 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:5E71538DD2D8A3B8|rigid:n6sDU6ZTdR8WlI4MAf56U1coZpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83086 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598237|imex:IM-9152-2157 author score:0.370673642 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:0D8028148238F26D|rigid:8R0FjvDoTBVDD2wLCSftVXB5X5U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83086 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598243|imex:IM-9152-2158 author score:0.368580626 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:F14684B13793E323|rigid:QcZHO8hTWhWBe+Hevmj41ES3lYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83086 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598261|imex:IM-9152-2161 author score:0.24075496 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:BE3A272D0560E721|rigid:3/VvqaFDQzFNVkodiQHE+u4hFPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83627 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598249|imex:IM-9152-2159 author score:0.364415477 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:0B8775F979135367|rigid:SeBA7kreSilV5lwfgCwbrHb0478 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83086 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598255|imex:IM-9152-2160 author score:0.32788086 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:AD1469E51686D95A|rigid:VvPaH3TZkhpraQ76l8dPKFdeOhc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83086 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598273|imex:IM-9152-2163 author score:0.167880558 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:B002085DC9253A32|rigid:Wgmq4nsdwd8cy4NpwlYuCxGsEMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83086 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598267|imex:IM-9152-2162 author score:0.174820751 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:ED63A7BD4546660D|rigid:E+6Zu1qe7D9DZ1/2UPsIw10uVng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83982 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598285|imex:IM-9152-2165 author score:0.159752337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:39D62AF83EFBC498|rigid:sR9+Wjw3q/Is4RYZggSFmKG0hGw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83086 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598279|imex:IM-9152-2164 author score:0.159752337 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:D6516E839D4D7CD9|rigid:JrmwYLFpsEprllZ/tdAer4OvV1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83086 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598291|imex:IM-9152-2166 author score:0.102330057 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:DD757EA6E7F344EE|rigid:0jLYOq5P/aRlU93ZYX9ChnAuLA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83667 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598303|imex:IM-9152-2168 author score:0.044785961 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:CD0C31068666F9AD|rigid:FHX8qAo0Xr/7N8JvpsrDr+5dtY4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83086 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598297|imex:IM-9152-2167 author score:0.048371069 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:0149B0E9C8F0C665|rigid:vFjL5+nzNzwxZ6QrpKd3FXUr4Bw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83767 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598309|imex:IM-9152-2169 author score:0.030357676 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:81A455B5177EBB62|rigid:0POPHXh6WxnpKERXV7FoYwbDopw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83282 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598315|imex:IM-9152-2170 author score:0.010275142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8A371672727E0000|rigid:3uM8C0oxeqguZEoNDyOsP0ExvWA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83086 uniprotkb:O83958 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598327|imex:IM-9152-2172 author score:0.000508764 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8B4E59A9E3C8EAD3|rigid:Ng+P6oUMJ31Pd/pgj1Y2BJijBeY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83086 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1598186|ensemblbacteria:AAC65043|ensemblbacteria:AGN75267 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83086_trepa(display_long)|uniprotkb:TP_0047(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598321|imex:IM-9152-2171 author score:0.008525287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005585(Protein of unknown function DUF327)|interpro:IPR024042|refseq:WP_010881496.1|ensemblbacteria:AAC65043(transcript)|ensemblbacteria:AGN75267(transcript)|ensemblbacteria:TP_0047(gene)|ensemblbacteria:TPANIC_0047(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0047; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:T9CbMorSblq+mscNLtaQO1H/Oq8243276 intact-crc:B9BC329FAC3FC2FC|rigid:j44P3diU3z+I05XsaZQ1fAVhgZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83074 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1598337|ensemblbacteria:AAC65032 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y031_trepa(display_long)|uniprotkb:TP_0031(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598342|imex:IM-9152-2174 author score:0.367817664 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 refseq:WP_010881480.1|ensemblbacteria:AAC65032(transcript)|ensemblbacteria:TP_0031(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0031; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:uBscc+CcVisiswFEc+NDygK13MM243276 intact-crc:AA0CFA500DC0DF30|rigid:96kbU6TPE5H2nvQW2YfzF5eJ60s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83572 uniprotkb:O83074 intact:EBI-1198361|intact:EBI-1581581|ensemblbacteria:AAC26565|ensemblbacteria:AGN75748 intact:EBI-1598337|ensemblbacteria:AAC65032 psi-mi:o83572_trepa(display_long)|uniprotkb:TP_0561(locus name) psi-mi:y031_trepa(display_long)|uniprotkb:TP_0031(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598333|imex:IM-9152-2173 author score:0.539515881 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007621(Protein of unknown function DUF477)|ensemblbacteria:AAC26565(transcript)|ensemblbacteria:AGN75748(transcript)|ensemblbacteria:TP_0561(gene)|ensemblbacteria:TPANIC_0561(gene)|go:"GO:0016021"(integral component of membrane) refseq:WP_010881480.1|ensemblbacteria:AAC65032(transcript)|ensemblbacteria:TP_0031(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0031; PREY protein TP_0561|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Qz8S1VEv+rYW7kZHpIWxd16RT+Q243276 rogid:uBscc+CcVisiswFEc+NDygK13MM243276 intact-crc:F1996750E5D00FB6|rigid:fQ6/B1ZFf68EIxVXIKZqFJ0EkG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83074 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1598337|ensemblbacteria:AAC65032 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y031_trepa(display_long)|uniprotkb:TP_0031(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598348|imex:IM-9152-2175 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010881480.1|ensemblbacteria:AAC65032(transcript)|ensemblbacteria:TP_0031(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0031; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:uBscc+CcVisiswFEc+NDygK13MM243276 intact-crc:2A91636853237081|rigid:uR1zKBbQE7HB1O6yu5HSZmt8XIM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83634 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598360|imex:IM-9152-2177 author score:0.535626377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:46CEAB5B0734088F|rigid:QQBmgepSndkZqdsDKTJTLDiG9Qc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83074 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1598337|ensemblbacteria:AAC65032 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y031_trepa(display_long)|uniprotkb:TP_0031(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598354|imex:IM-9152-2176 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010881480.1|ensemblbacteria:AAC65032(transcript)|ensemblbacteria:TP_0031(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0031; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:uBscc+CcVisiswFEc+NDygK13MM243276 intact-crc:8842A775178169C6|rigid:BkDcbwdsfXwxxRcwnAtElvv+dLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O66107 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598369|imex:IM-9152-2178 author score:0.475131818 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:7A2FA7EA483ACF28|rigid:bRs4OomVf2dlDd1PAVePcW0mbkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83412 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598375|imex:IM-9152-2179 author score:0.448373455 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:043F6C0562C57EE6|rigid:aYUZEOjVhQ6Q4TcHKW8aRThCxm0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83563 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598381|imex:IM-9152-2180 author score:0.441724236 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:6BD4D377341F8414|rigid:A2iXR7fAUoeSqJajwlHOmHdkX9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83563 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598387|imex:IM-9152-2181 author score:0.327663494 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:7A6386179FC78682|rigid:qe0TS8SUVagd7IocTItIldIgtx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83463 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598393|imex:IM-9152-2182 author score:0.287567173 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:0169531DE7BC1B2A|rigid:HooPIJsEjQMkChIIC0RS3PpUIFw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83563 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598405|imex:IM-9152-2184 author score:0.21684568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:182EC70E861153BE|rigid:4OL9NsS1CDNLsW+8H/5WdU7CqOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83563 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598399|imex:IM-9152-2183 author score:0.221452594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:000184E34EB29A9B|rigid:nvKgWN4SaRLS8b5fSH/sQa8MpXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83531 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598411|imex:IM-9152-2185 author score:0.194856647 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:5C7DE8661F488E89|rigid:wWV+hg3IPMSlIZFXeJCIGLN2mdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83099 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598423|imex:IM-9152-2187 author score:0.163264557 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:03B6317C50343F53|rigid:UpHegRYEWybp+Jvun65y3QE8ko4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83563 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598417|imex:IM-9152-2186 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:8EB35F29EEA1E6C8|rigid:TrwTSYAZ8sMUCId8Zq7opDu/0Dw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:P21992 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598429|imex:IM-9152-2188 author score:0.15961996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:FBEA3EA60AB85B39|rigid:/A0yz7Tlr3JrD6v5i+BbO4PVh5M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83927 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598435|imex:IM-9152-2189 author score:0.142378866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:D3FEA467362108F5|rigid:DPvbxkSw0qqYCe/8cIIdtPzJboc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83877 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598447|imex:IM-9152-2191 author score:0.076163326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:0194C6BBD8F021B5|rigid:hJOHc+p5YEwt86NrFDougqaKKbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83574 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598441|imex:IM-9152-2190 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:F9FF45C8DD4173D1|rigid:GwxQNzHwliCMLwT7YaXY4v7tVak false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83954 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598459|imex:IM-9152-2193 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1ACDBF73F0CE4016|rigid:NgZ5EOSRTf5ZL6XLYtyC8FpssoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83563 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598453|imex:IM-9152-2192 author score:0.014894287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:93431D93CA77E846|rigid:QmCJMbG2x1q5ELWk295AvCnvZqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83500 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1598471|ensemblbacteria:AAC65482 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y487_trepa(display_long)|uniprotkb:TP_0487(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598474|imex:IM-9152-2195 author score:0.531364063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|ensemblbacteria:AAC65482(transcript)|ensemblbacteria:TP_0487(gene)|refseq:WP_010881936.1|interpro:IPR011989(Armadillo-like helical) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0487|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:IhdwVzcDmzqfP+kof/3w9Gs8f2U243276 intact-crc:8E67338DB65ED0AF|rigid:HFlcmhG0O77UKovXKni6amNuj14 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83958 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598465|imex:IM-9152-2194 author score:0.000740763 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0552; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:F4C7A6A96A949C01|rigid:KPWfGqo1vs9A2pWcNOaZAHP2Ir4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83436 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598486|imex:IM-9152-2197 author score:0.511211561 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0421|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 intact-crc:22DAFB073046C6BA|rigid:AlacKPRUhcgER6GWXLy/wFZo0oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83133 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598480|imex:IM-9152-2196 author score:0.513376653 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:31CE1F4C78C5B77F|rigid:ohNLjAx9nxLleQEmLatZyahRhvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83158 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598492|imex:IM-9152-2198 author score:0.491022549 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:ACA0DF121016EC0D|rigid:n+luhx8t/uN8LvgMd8CBH7yMXlo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83702 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598498|imex:IM-9152-2199 author score:0.457471497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:5C6D47DA87B9E9D5|rigid:Fu/0SQvtn4j07cVAca46/28GcPc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83395 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598504|imex:IM-9152-2200 author score:0.457471497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:AB3439B9629927AB|rigid:/m7SsVl4kvoYlSYEKGCXPVcv8Hk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83459 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598510|imex:IM-9152-2201 author score:0.420251377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:4991AD3CEF67E78F|rigid:2XIZ8y8YN7/iUDnWLoTd6qQz2aI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83570 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598516|imex:IM-9152-2202 author score:0.366458388 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:DFCF376580E535F3|rigid:jgzoPZtAssBBTOcTCUEOFtYURZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83395 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598522|imex:IM-9152-2203 author score:0.341834299 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:E5B46D04A820B596|rigid:7LEJOTv895SNrbDY/bDbYIWec8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83395 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598528|imex:IM-9152-2204 author score:0.32390178 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:903083E482E4B4F3|rigid:hcFQGk5nhptoU1dq59Fpy29v/rE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83395 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598534|imex:IM-9152-2205 author score:0.262687777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:4C6AE8D513879E09|rigid:GMdW4bsR7W74GveiZLTVlLo58DY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83395 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598540|imex:IM-9152-2206 author score:0.227848013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:3DB0F7790D5CAABC|rigid:DVTxNtXKknY70k4L3LHJI3G6E38 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83531 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598546|imex:IM-9152-2207 author score:0.150328149 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:853CBAEBB99475C7|rigid:OFOQNZAtvDM4p3lg+72MPf7Di8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83395 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598552|imex:IM-9152-2208 author score:0.137084463 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:E60D0BCF2E3A5051|rigid:FQQXd0w9YvE/ZuMGjy89jd2Ap3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83395 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598558|imex:IM-9152-2209 author score:0.127807271 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:4CC9988936CAAA35|rigid:Lxnj5c7IQLGAw/b+eb0XQpeMN/0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:P21992 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598564|imex:IM-9152-2210 author score:0.121924355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:4AEE9DFF1A638A20|rigid:fpccwsWGeRjBA7jQMGXg5mbKNu0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83667 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598576|imex:IM-9152-2212 author score:0.047544104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:7D36B3686B45BA30|rigid:YmlqcBjcCBcYppPS32IUSt30Wag false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83767 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598582|imex:IM-9152-2558 author score:0.03225726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E31A3F643D7B00D7|rigid:n0jU/1e7mcd3/bRlr4FOmGjTHXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83413 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598570|imex:IM-9152-2211 author score:0.051338134 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:C5691FB235AD0847|rigid:5rIbnpBEivMSesoaGMrMoSLJiE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83395 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598588|imex:IM-9152-2559 author score:0.02686547 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:EE3460D7A4A22F2D|rigid:LpylNOSEPaxPd2zVvSONTwyNj4E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83395 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598594|imex:IM-9152-2560 author score:0.010932261 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:930CA5059472E3E2|rigid:PmclQ9un7KOllzgde+IGaOZH6Sg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83954 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598600|imex:IM-9152-2561 author score:0.009071525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:8210F0D23F5E1559|rigid:MH+FVkGYe4CDDUOyaIRIO5evc9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83806 uniprotkb:O83353 intact:EBI-1598619|ensemblbacteria:AAC65798 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:syy_trepa(display_long)|uniprotkb:tyrS(gene name)|psi-mi:tyrS(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0834(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598615|imex:IM-9152-2563 author score:0.531364063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR024088|interpro:IPR024107|ensemblbacteria:AAC65798(transcript)|ensemblbacteria:TP_0834(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006437"(tyrosyl-tRNA aminoacylation)|interpro:IPR036986|refseq:WP_014342602.1 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0834|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wZsW+MogxpTWOBr/a4m2VWwEESA243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:89235650D9BC44ED|rigid:Q5tTiz7ujXDvx6z26nBlq6dkeXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83395 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598606|imex:IM-9152-2562 author score:0.000541643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0380; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 intact-crc:09775C619D5EA318|rigid:iya0SP5hUWKIkPkUp7x5tH1TNgU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83478 uniprotkb:O83353 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598631|imex:IM-9152-2565 author score:0.491022549 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:85EE9110F0A4FD4A|rigid:G9sMs3/aT85+QXyVVC+4O5PC4N8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83353 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598637|imex:IM-9152-2566 author score:0.479424189 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:B21B4AD86FB6F075|rigid:/rokEt0z07a3KFfHtPXBHxsxvu8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83910 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1596205|ensemblbacteria:AAC65899 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:y940_trepa(display_long)|uniprotkb:TP_0940(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598625|imex:IM-9152-2564 author score:0.531364063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 ensemblbacteria:AAC65899(transcript)|ensemblbacteria:TP_0940(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0940|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:ilySwJt49PRWwS9/gzSuMpgOg54243276 intact-crc:B020D03ACAC19ACF|rigid:pqgNSVtgqBQV3fe2hE3LWs7bVnE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83634 uniprotkb:O83353 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598643|imex:IM-9152-2567 author score:0.457471497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:EA55992FCDFD248D|rigid:NPM1rjwo1M53hs56yenqIFZQuyk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83542 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598655|imex:IM-9152-2569 author score:0.411205684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:44A876488D1A9C71|rigid:7vzAsbjB6CErkqf0Y5a8zVV4azU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83595 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598649|imex:IM-9152-2568 author score:0.430891214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:44CD0E8C4156D7A5|rigid:t12+49YVUVNk52oShMeDpacvBDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O66106 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598661|imex:IM-9152-2570 author score:0.411205684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:36813B8C7C6645FF|rigid:K9DqX97mAJwPjjGElSMwCevWkhI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83353 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598667|imex:IM-9152-2571 author score:0.385403935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:7E87FD442264BF1B|rigid:BcHKYTYfccZ/FKXzehm56pu0xVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83565 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598679|imex:IM-9152-2573 author score:0.32390178 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:DCF4C757D119B0A1|rigid:h+PPP9zZmedEgQOhEHnJ6ewJGr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83353 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598673|imex:IM-9152-2572 author score:0.379046866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:26CE900F20631F24|rigid:Y24Gs04UOQXhrkFwLj6Ogh1H1as false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83670 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598685|imex:IM-9152-2574 author score:0.318034215 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:0BF7EEDC5A415942|rigid:jJ9o+Q/c3gQFxuCE6cALBMoyuG4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83805 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598691|imex:IM-9152-2575 author score:0.318034215 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:62345BF855E8E770|rigid:VEQ3lfFaCdUb1LVLQNun3idStDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83463 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598703|imex:IM-9152-2577 author score:0.227848013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:46CEEC6DBD0454B0|rigid:YynlS9MtYE3ZdvDF4BeAWqFVq4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83709 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598697|imex:IM-9152-2576 author score:0.252392965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:5951201D6FEE823B|rigid:YS5/zAbQWvT9wHWjy75tCAMmUHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83353 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598709|imex:IM-9152-2578 author score:0.221592874 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:1EF2702715F7F3D8|rigid:+zojk5CtGrYQovRfAWG5BNqLQ0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83353 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598721|imex:IM-9152-2580 author score:0.172145866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:3F19BFD81D59D46E|rigid:s5H02Jqv6lgO60jLkJRvW4k6Igs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83353 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598715|imex:IM-9152-2579 author score:0.182902516 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:EBB2CE951DD6ED3B|rigid:rKRPg4OBdWzf/ECoD9otwLMlR+s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83353 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598727|imex:IM-9152-2581 author score:0.150328149 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:FE42A1FF09CC8BCB|rigid:6O6L2wxGG/wkRXme84gwmmejn0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83877 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598733|imex:IM-9152-2582 author score:0.056843589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:3DC85FD2C9B3A1A0|rigid:DAlH3cj/91HcZ7TkyW3o8s6Nnq0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83353 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598739|imex:IM-9152-2583 author score:0.047544104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 intact-crc:0648A87CDB1D443C|rigid:R81O3zdMY3ZMHRjYo7woaAEwaj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83767 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598745|imex:IM-9152-2584 author score:0.03225726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:AFDE7BD76E860485|rigid:SCAGeuv4d1GiUGVbe+YrJWKVmws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83927 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598763|imex:IM-9152-2587 author score:0.237013371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:E75285316566A298|rigid:gqjj7HXvBUM+wjSWkJpvVbmCVjY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83738 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598757|imex:IM-9152-2586 author score:0.530749869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:62B5FDD5988100AB|rigid:wWpfpNRDZbT1S6jM6LL3k8nfweU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83353 uniprotkb:O83954 intact:EBI-1598612|ensemblbacteria:AAC65320|ensemblbacteria:AGN75531 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83353_trepa(display_long)|uniprotkb:TP_0333(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598751|imex:IM-9152-2585 author score:0.009071525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004564(Outer membrane lipoprotein carrier protein LolA)|refseq:WP_010881781.1|ensemblbacteria:AAC65320(transcript)|ensemblbacteria:AGN75531(transcript)|ensemblbacteria:TP_0333(gene)|ensemblbacteria:TPANIC_0333(gene)|interpro:IPR029046 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0333; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6pP15tbx8vBJKtHb2G/m/+S4FIs243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F96EEBC68F06EB55|rigid:ECWulIzslpHhkA62S1F6jnqA/6k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83967 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598769|imex:IM-9152-2588 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 intact-crc:41DF36676D5358A0|rigid:grcAwFK6QTQ39ZIIAg5wLgPq1ho false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83767 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598781|imex:IM-9152-2590 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0545BF7E7803F1B7|rigid:DpxWbU1gifVYpcf4JhyBUP30uM4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83877 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598775|imex:IM-9152-2589 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:10FD624376F98790|rigid:pzOHZaBdykFRsChot8MX6RXgg7c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83967 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598787|imex:IM-9152-2591 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 intact-crc:88F3368C9E21AD95|rigid:DGN94bGQ2eEx2Mxvk+egUx4sD00 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83954 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598793|imex:IM-9152-2592 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:2B1FF97F227C7D3C|rigid:caSIPY4CQwEFDa/u1nQWinpmj+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83967 uniprotkb:O83958 intact:EBI-1596655|ensemblbacteria:AAC65951|ensemblbacteria:AGN76166 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83967_trepa(display_long)|uniprotkb:TP_1002(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598799|imex:IM-9152-2593 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018725|ensemblbacteria:AAC65951(transcript)|ensemblbacteria:AGN76166(transcript)|ensemblbacteria:TP_1002(gene)|ensemblbacteria:TPANIC_1002(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1002; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:YGPt1k5Dn+dwXxSyIon7TZrQOZE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D675241C585D8BF1|rigid:qpA24mdOPPKimeeJk3QOAy2X/Go false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83311 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598805|imex:IM-9152-2594 author score:0.528678094 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:38D38FE3B8B8BC4A|rigid:3MumJkulofBr9B4UIK+VHNGkP74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83969 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598817|imex:IM-9152-2596 author score:0.29278387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:863C4EF0F075173C|rigid:g70MBBolw+MRwYknT0INF1Ymoes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83398 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598823|imex:IM-9152-2597 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:943E9139C9097771|rigid:bme0F7e969qKP4jt3cqnJcOA42c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83305 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598811|imex:IM-9152-2595 author score:0.292909869 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:57C1485F99E57135|rigid:ny0DVpHsFAdzj18EAyRHZKA111g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83279 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582625|ensemblbacteria:AAC65237 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598829|imex:IM-9152-2598 author score:0.287365105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 intact-crc:7BB9D5426ABFCF30|rigid:pIsJO71D8rZfvi+sV3GNS/OZ4zw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83413 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598841|imex:IM-9152-2600 author score:0.097315309 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:B64DB18321F3A8A2|rigid:hgJEqaqQ/jBTu/YhxsRWfjAeo8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83531 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598835|imex:IM-9152-2599 author score:0.260604688 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:4CEE434BAFA45727|rigid:xHbrZs0skCs/SKfQtYBypYkvQqE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83279 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1582625|ensemblbacteria:AAC65237 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598847|imex:IM-9152-2601 author score:0.062267707 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 intact-crc:4C5517BC7C806E32|rigid:mP2UrAn9Er/qd9BwpD8ecXLUAMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83745 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598853|imex:IM-9152-2602 author score:0.052129895 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:10DF45B7B651CAA5|rigid:qrA8bmRGW8ZywSjOIX8BqH47TRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83279 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582625|ensemblbacteria:AAC65237 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598865|imex:IM-9152-2604 author score:0.01791041 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 intact-crc:E100E944AC271A2F|rigid:wBhdh6wxgfpyIzG5I5s865pudbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83282 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598859|imex:IM-9152-2603 author score:0.021544746 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:104B990CEAABB755|rigid:idGkhaoFUvZ8tsQNEKgKyvzDfP0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83232 uniprotkb:O83709 intact:EBI-1598877|ensemblbacteria:AAC65191 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:rs14z_trepa(display_long)|uniprotkb:rpsZ(gene name)|psi-mi:rpsZ(display_short)|uniprotkb:rpsN(gene name synonym)|uniprotkb:TP_0202(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598881|imex:IM-9152-2606 author score:0.526113444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR023053|interpro:IPR043140|refseq:WP_010881649.1|ensemblbacteria:AAC65191(transcript)|ensemblbacteria:TP_0202(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0202; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4Vx/vbuRvmKX99X+cN3dBGPNcTk243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:AD78D5E638971B73|rigid:jzAAOlRTvbyN+2lNWpiXf9XhA+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83279 uniprotkb:O83958 intact:EBI-1582625|ensemblbacteria:AAC65237 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:lnt1_trepa(display_long)|uniprotkb:lnt1(gene name)|psi-mi:lnt1(display_short)|uniprotkb:TP_0252(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598871|imex:IM-9152-2605 author score:0.002043484 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004563(Apolipoprotein N-acyltransferase)|interpro:IPR003010(Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0042158"(lipoprotein biosynthetic process)|ensemblbacteria:AAC65237(transcript)|ensemblbacteria:TP_0252(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881701.1|interpro:IPR036526 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0252; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tImm9QTFMz/vG7dBNgPZUjqQoxU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6CE44EF984F61034|rigid:SK1hplrAYdOMhwftU/pTcUSftjs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83232 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1598877|ensemblbacteria:AAC65191 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rs14z_trepa(display_long)|uniprotkb:rpsZ(gene name)|psi-mi:rpsZ(display_short)|uniprotkb:rpsN(gene name synonym)|uniprotkb:TP_0202(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598887|imex:IM-9152-2607 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR023053|interpro:IPR043140|refseq:WP_010881649.1|ensemblbacteria:AAC65191(transcript)|ensemblbacteria:TP_0202(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0202; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:4Vx/vbuRvmKX99X+cN3dBGPNcTk243276 intact-crc:B46824994381C12D|rigid:liNORDEgF48xrQUHktohrH0nplI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83232 uniprotkb:O83767 intact:EBI-1598877|ensemblbacteria:AAC65191 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:rs14z_trepa(display_long)|uniprotkb:rpsZ(gene name)|psi-mi:rpsZ(display_short)|uniprotkb:rpsN(gene name synonym)|uniprotkb:TP_0202(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598893|imex:IM-9152-2608 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR023053|interpro:IPR043140|refseq:WP_010881649.1|ensemblbacteria:AAC65191(transcript)|ensemblbacteria:TP_0202(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0202; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4Vx/vbuRvmKX99X+cN3dBGPNcTk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:735E056B040A27B5|rigid:fmS/X/SL5TqvASra8WOIZRHkL6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83497 uniprotkb:O83970 intact:EBI-1598909|ensemblbacteria:AAC65473 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y484_trepa(display_long)|uniprotkb:TP_0484(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598905|imex:IM-9152-2610 author score:0.523916525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006860(FecR protein)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_010881933.1|ensemblbacteria:AAC65473(transcript)|ensemblbacteria:TP_0484(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0484; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZK0sg3rIJWcJRnlGz7MEfkz+wZM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:01330CF768B6677B|rigid:L2VcPrw4vN80xRl5YWOLg/O8C9Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83232 uniprotkb:O83958 intact:EBI-1598877|ensemblbacteria:AAC65191 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rs14z_trepa(display_long)|uniprotkb:rpsZ(gene name)|psi-mi:rpsZ(display_short)|uniprotkb:rpsN(gene name synonym)|uniprotkb:TP_0202(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598899|imex:IM-9152-2609 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR023053|interpro:IPR043140|refseq:WP_010881649.1|ensemblbacteria:AAC65191(transcript)|ensemblbacteria:TP_0202(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0202; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4Vx/vbuRvmKX99X+cN3dBGPNcTk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:22557DC88495A11D|rigid:WkGEgsL8Z3L3yY6aikAKuPsnO3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83497 uniprotkb:O83574 intact:EBI-1598909|ensemblbacteria:AAC65473 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y484_trepa(display_long)|uniprotkb:TP_0484(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598914|imex:IM-9152-2611 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006860(FecR protein)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_010881933.1|ensemblbacteria:AAC65473(transcript)|ensemblbacteria:TP_0484(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0484; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZK0sg3rIJWcJRnlGz7MEfkz+wZM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:AA20F726A6512173|rigid:NMzgfNXRXV+2wmyxZVk/5gkPLo0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83497 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1598909|ensemblbacteria:AAC65473 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y484_trepa(display_long)|uniprotkb:TP_0484(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598920|imex:IM-9152-2612 author score:0.15694401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR006860(FecR protein)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_010881933.1|ensemblbacteria:AAC65473(transcript)|ensemblbacteria:TP_0484(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0484; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ZK0sg3rIJWcJRnlGz7MEfkz+wZM243276 intact-crc:0C7C2E714AA7A366|rigid:qO2rlLA1UnBm2QUnmDDVOKVSRtQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83497 uniprotkb:O83954 intact:EBI-1598909|ensemblbacteria:AAC65473 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y484_trepa(display_long)|uniprotkb:TP_0484(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598926|imex:IM-9152-2613 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006860(FecR protein)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_010881933.1|ensemblbacteria:AAC65473(transcript)|ensemblbacteria:TP_0484(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0484; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZK0sg3rIJWcJRnlGz7MEfkz+wZM243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:FE524101A04584CD|rigid:6ivAFc0R53KibyE76deOiG+ONkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83497 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1598909|ensemblbacteria:AAC65473 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y484_trepa(display_long)|uniprotkb:TP_0484(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598932|imex:IM-9152-2614 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006860(FecR protein)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_010881933.1|ensemblbacteria:AAC65473(transcript)|ensemblbacteria:TP_0484(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0484; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ZK0sg3rIJWcJRnlGz7MEfkz+wZM243276 intact-crc:77B52E00BE7F6BB0|rigid:Xm/FRd4IhCw7NQLzGipsX/wuc18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83648 uniprotkb:O83463 intact:EBI-1598942|ensemblbacteria:AAC65616|ensemblbacteria:AGN75822 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83648_trepa(display_long)|uniprotkb:TP_0642(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598938|imex:IM-9152-2615 author score:0.523793491 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|refseq:WP_010882087.1|ensemblbacteria:AAC65616(transcript)|ensemblbacteria:AGN75822(transcript)|ensemblbacteria:TP_0642(gene)|ensemblbacteria:TPANIC_0642(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016868"(intramolecular transferase activity, phosphotransferases)|interpro:IPR036900 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0642; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kZL3JtxC01YcTSCzkm4HE2TgxY243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:0926968F74191258|rigid:4hgLbsO/SjShqlz2/BD4gky6KOA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83648 uniprotkb:O83099 intact:EBI-1598942|ensemblbacteria:AAC65616|ensemblbacteria:AGN75822 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83648_trepa(display_long)|uniprotkb:TP_0642(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598947|imex:IM-9152-2616 author score:0.347134018 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|refseq:WP_010882087.1|ensemblbacteria:AAC65616(transcript)|ensemblbacteria:AGN75822(transcript)|ensemblbacteria:TP_0642(gene)|ensemblbacteria:TPANIC_0642(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016868"(intramolecular transferase activity, phosphotransferases)|interpro:IPR036900 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0642; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kZL3JtxC01YcTSCzkm4HE2TgxY243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:85DFF9E8DDF76378|rigid:bddoxQAmrXmBktlz8hsKSRPWg4Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83816 uniprotkb:O83463 intact:EBI-1598953|ensemblbacteria:AAC65812 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:g3p_trepa(display_long)|uniprotkb:gap(gene name)|psi-mi:gap(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)|uniprotkb:TP_0844(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598957|imex:IM-9152-2617 author score:0.523793491 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|refseq:WP_010882288.1|ensemblbacteria:AAC65812(transcript)|ensemblbacteria:TP_0844(gene)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR036291 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0844; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GhBe+2/+3tJypLr8c8og/6Is0w0243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:FE791F6EC269AF07|rigid:wBefslLNLJmgrR350dk0o+yDpoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83816 uniprotkb:P21992 intact:EBI-1598953|ensemblbacteria:AAC65812 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:g3p_trepa(display_long)|uniprotkb:gap(gene name)|psi-mi:gap(display_short)|uniprotkb:NAD-dependent glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)|uniprotkb:TP_0844(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598963|imex:IM-9152-2618 author score:0.341057897 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020831|interpro:IPR020830|interpro:IPR020829|interpro:IPR020828|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|refseq:WP_010882288.1|ensemblbacteria:AAC65812(transcript)|ensemblbacteria:TP_0844(gene)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR036291 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0844; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GhBe+2/+3tJypLr8c8og/6Is0w0243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:E5C173F861BF2721|rigid:blJOg2+U+jURqnbzD/hOTkpPJFc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83539 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598985|imex:IM-9152-2621 author score:0.515490037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:99154EBAE2AD0A4E|rigid:Dv+ueHusOOnwXAPoqBaYt0WgafE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83931 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598969|imex:IM-9152-2619 author score:0.522210988 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:E49B6CFE7936B211|rigid://3Y/U28WQC6xtZk28IrqLSkIus false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83539 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598979|imex:IM-9152-2620 author score:0.515490037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:29D7FBAEECACE61B|rigid:zdNzUp6kMOuAGQVIb6Z+SeOZIBg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83098 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598991|imex:IM-9152-2622 author score:0.475131818 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:F351B6C79C828A03|rigid:ec0OLIzNbyG4ZkEWkuaJODxeSv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83463 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1598997|imex:IM-9152-2623 author score:0.287567173 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:B3E4E30322879D31|rigid:7KEGLeI2Z6Iv167EWRv4bQry6gQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83398 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599003|imex:IM-9152-2624 author score:0.21684568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:52EAC9CEBA924A7D|rigid:NAI9sph3Jih3YJtWDdu9GarI9Ys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83982 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599009|imex:IM-9152-2625 author score:0.21684568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:3113569791BF5006|rigid:13vzGEyUE5aBIZbPfSndZvG76yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83539 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599015|imex:IM-9152-2626 author score:0.166975838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:3C3EEF372B9A60D3|rigid:H0iHHAipjwwsekfePGA4idUJrK0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83539 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599021|imex:IM-9152-2627 author score:0.163264557 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:B13B8162950FB948|rigid:Wpd36+qWIxrK8tIrLmOBSijE2Rs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83539 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599027|imex:IM-9152-2628 author score:0.15961996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:D403E67CA100B790|rigid:X/wzS5krnrjDpfv5S+HqffoZA6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83539 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599033|imex:IM-9152-2629 author score:0.142378866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:35F639AFE98DB51B|rigid:/VMYaGjGbHxhDD3uzvRvqbY9oBM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83574 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599039|imex:IM-9152-2630 author score:0.11527328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:D6169D1276F99F78|rigid:lRuwpnAA5t1RSpwQlnpnDGbR9nY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83539 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599045|imex:IM-9152-2631 author score:0.076163326 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:E79C5B73075C9C5B|rigid:O737jvAV743GpIM0KLjncPYCjkA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83413 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599051|imex:IM-9152-2632 author score:0.068923443 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:0753487C159476AF|rigid:TtnkO3EQ3oYsBKlTLJj+a8MzEFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83539 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599057|imex:IM-9152-2633 author score:0.063917372 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:39DFC4DD12DAC84C|rigid:SKwjWlMYW7lYR11pZh5rBfAYkM0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83539 uniprotkb:O83958 intact:EBI-1598973|ensemblbacteria:AAC65514 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599075|imex:IM-9152-2636 author score:0.000740763 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:12CF3B61B53821EF|rigid:qcWHAWHf5NhF2k8GbHKhzNtc5Uo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83539 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599063|imex:IM-9152-2634 author score:0.036389495 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:1D40AF8E76B46F70|rigid:cCveaYh10bjbHo+PNsE+50Eu65U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83539 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1598973|ensemblbacteria:AAC65514 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:vatd2_trepa(display_long)|uniprotkb:atpD2(gene name)|psi-mi:atpD2(display_short)|uniprotkb:V-ATPase subunit D 2(gene name synonym)|uniprotkb:TP_0527(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599069|imex:IM-9152-2635 author score:0.012367623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010881975.1|ensemblbacteria:AAC65514(transcript)|ensemblbacteria:TP_0527(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0527; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:NpvqhWj1+SpgjPDu9Cs7j0z39jo243276 intact-crc:FCC522BB2F62FDF8|rigid:Ed+XSI0LfrqoSmdmM9Hkk23031A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83960 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1583870|ensemblbacteria:AAC26583 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83960_trepa(display_long)|uniprotkb:TP_0995(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599081|imex:IM-9152-2637 author score:0.520135599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC26583(transcript)|ensemblbacteria:TP_0995(gene)|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0995|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:e/7IeUNCDYEoLFDH9to3t6L3g3E243276 intact-crc:E4605238577BD8A1|rigid:41J6Bu9fpBfpWh4Rvr62wDf47t0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83310 uniprotkb:O83098 intact:EBI-1588258|ensemblbacteria:AAC65268 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599087|imex:IM-9152-2638 author score:0.493224433 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:E4C9DD157F88C5EA|rigid:hjCVA6Mi3PMPvRAOX/xrWq5tJQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83098 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599093|imex:IM-9152-2639 author score:0.466352473 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:ABBCDEDC1122D6E7|rigid:v08jWApO6g+qH0P6EUNTBTCJ/zQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83542 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599099|imex:IM-9152-2640 author score:0.426455211 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:1AAD19B270290B7F|rigid:A16ZIMo8aL1/r3Jk0ql/PGAwDPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83098 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599105|imex:IM-9152-2641 author score:0.426455211 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:46549D514884CCF8|rigid:JQYUE8/TyaCzFxqyDKFC/ThvKqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83098 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599111|imex:IM-9152-2642 author score:0.413340315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:D17F586812F94EB3|rigid:ye0Ha9DV5WofXY2NqXF1uSSB+Wg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O66107 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599117|imex:IM-9152-2643 author score:0.413340315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:A42259BBA3D73695|rigid:hD7NboyILU74MU4ilQ2yBfE0JSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83098 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599123|imex:IM-9152-2644 author score:0.400347215 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:3F35CEFD34067277|rigid:22aZ6pQKFalXaeUZmxC34IEYd9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83752 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599141|imex:IM-9152-2647 author score:0.356066965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:C430B9CB424C452B|rigid:8AHNVA2ek4nQrfxxGZqUCXOWXdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83311 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599129|imex:IM-9152-2645 author score:0.3747931 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:D77BDB55D920641E|rigid:bwuEyGMBHgphi3pOaWAa1c3gI/w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83459 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599135|imex:IM-9152-2646 author score:0.356066965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:E14AF74FDAEF7077|rigid:b13/HRWBxIxFc1iw94m0v+WU8E0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83565 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599147|imex:IM-9152-2648 author score:0.337770981 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:45C24903681C683E|rigid:5j+8h7z3RITxvh3OS+IM4XQgLSI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83098 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599153|imex:IM-9152-2649 author score:0.264397636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:A2067BABFC242D9C|rigid:3EQgTS3v82EXQTzWaqZ78Hc/BBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83305 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599159|imex:IM-9152-2650 author score:0.18125911 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:223C4350AC8555EA|rigid:PBBuz0mVV/HNz0mDfxWgYvplMX0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83398 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599165|imex:IM-9152-2651 author score:0.177297932 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:341DFD4E920E87FF|rigid:dVSsE+CrToPahC/Nvm7+uautx9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83098 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599171|imex:IM-9152-2652 author score:0.054476779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:5B70698C2B1C5118|rigid:FdWNpt5eFOZxW+TJe466rJX4VGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83098 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599177|imex:IM-9152-2653 author score:0.050463133 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:D367AA3F470FA275|rigid:ouk723I3jsZG0E0ag8/f/leEoLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83767 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599183|imex:IM-9152-2654 author score:0.034271505 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:ACBD1E314344B2C1|rigid:bMExQu24HycILQKzlU3VmJ1ddwI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83745 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599189|imex:IM-9152-2655 author score:0.028552969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:0FD2FC0DDD13FADF|rigid:o06IQX7qECCb69HaN9d3ZkOKGaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83282 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599195|imex:IM-9152-2656 author score:0.01163091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:DB9CD5EEE1801633|rigid:74Us0+DEtLem7GvmF+myhMtXbTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83954 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599201|imex:IM-9152-2657 author score:0.00965242 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:C2E41F52388BF293|rigid:/LX3TXlP3H7y/bSW4npMrTppBbI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83098 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599207|imex:IM-9152-2658 author score:0.000576645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0059; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:D43E2757A64F3B49|rigid:LFFETrOziBsn4DCEiDUvhwo+d6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83047 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1582316|ensemblbacteria:AAC64999 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599213|imex:IM-9152-2659 author score:0.51793636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0001|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 intact-crc:AE6D534FCD1C724D|rigid:MYK+8PdxnZe4sSEfCV87BFFGWkY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83395 uniprotkb:O83213 intact:EBI-1591145|ensemblbacteria:AAC65366|ensemblbacteria:AGN75575 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83395_trepa(display_long)|uniprotkb:TP_0380(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599231|imex:IM-9152-2662 author score:0.504482702 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032830|interpro:IPR032438|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|ensemblbacteria:AAC65366(transcript)|ensemblbacteria:AGN75575(transcript)|ensemblbacteria:TP_0380(gene)|ensemblbacteria:TPANIC_0380(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:WP_010881828.1|interpro:IPR027417 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0380|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ancII8Il8rITiSNPnl/N0VkhaG0243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:153B06674894CFAA|rigid:WmaLP4KG4tc7EVHxuAksHghXQPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83654 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1198390|intact:EBI-1581968|ensemblbacteria:AAC65621|ensemblbacteria:AGN75828 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:o83654_trepa(display_long)|uniprotkb:TP_0648(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599219|imex:IM-9152-2660 author score:0.51793636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010882093.1|ensemblbacteria:AAC65621(transcript)|ensemblbacteria:AGN75828(transcript)|ensemblbacteria:TP_0648(gene)|ensemblbacteria:TPANIC_0648(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0648|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:/p+6DxYCl/0mcmssQQa9jg70UTg243276 intact-crc:C622AF2A1CE2C9FD|rigid:Zb4I0UQbZ214h+f1Y9zofq0hmjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83436 uniprotkb:O83213 intact:EBI-1198509|intact:EBI-1583135|ensemblbacteria:AAC65409|ensemblbacteria:AGN75615 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83436_trepa(display_long)|uniprotkb:TP_0421(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599225|imex:IM-9152-2661 author score:0.511211561 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:WP_010881869.1|ensemblbacteria:AAC65409(transcript)|ensemblbacteria:AGN75615(transcript)|ensemblbacteria:TP_0421(gene)|ensemblbacteria:TPANIC_0421(gene) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0421|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uAXXwBzuJ+F0cQFr/WXbhXayqp8243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:41671C4873A9E029|rigid:8LIdwQIhitTvPiHxj1W6r5+J9a8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83527 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1581703|ensemblbacteria:AAC65502 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:uvra_trepa(display_long)|uniprotkb:uvrA(gene name)|psi-mi:uvrA(display_short)|uniprotkb:Excinuclease ABC subunit A(gene name synonym)|uniprotkb:TP_0514(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599237|imex:IM-9152-2663 author score:0.491022549 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR004602(Excinuclease ABC, A subunit)|ensemblbacteria:AAC65502(transcript)|ensemblbacteria:TP_0514(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009380"(excinuclease repair complex)|go:"GO:0009381"(excinuclease ABC activity)|go:"GO:0009432"(SOS response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:WP_010881963.1|interpro:IPR027417|interpro:IPR041102|interpro:IPR041552 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0514|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:roFG5ff5EO6HZs2OascSWpkq9Lk243276 intact-crc:64B08467F5FB47B6|rigid:vtobcHygmMpI8ye77sDPww789Jc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83373 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599243|imex:IM-9152-2664 author score:0.484296132 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:4EDC39CCA9CCD723|rigid:jt8Y1xyM+GRUU+4qAPViHzgt3vQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83213 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599249|imex:IM-9152-2665 author score:0.470862777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0092|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:429C9D04477529F8|rigid:87BmlkUn1m8TBQwNEfZAfCBBKsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83105 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599255|imex:IM-9152-2666 author score:0.464160677 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0066|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 intact-crc:E16717686E4ABC54|rigid:d6AUSlqE7sVPHWhMDbbufnigsig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83634 uniprotkb:O83213 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599261|imex:IM-9152-2667 author score:0.457471497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:F29665743E4AFC12|rigid:bJxjfRvJFIl/QaGaSHtm2oX5ofo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83909 uniprotkb:O83213 intact:EBI-1198910|intact:EBI-1584197|ensemblbacteria:AAC65895|ensemblbacteria:AGN76104 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83909_trepa(display_long)|uniprotkb:TP_0939(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599267|imex:IM-9152-2668 author score:0.457471497 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029061|interpro:IPR017896|interpro:IPR017900|interpro:IPR019456|interpro:IPR019752|interpro:IPR002880(Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal)|interpro:IPR011895("Pyruvate:ferredoxin (flavodoxin) oxidoreductase")|interpro:IPR002869(Pyruvate ferredoxin/flavodoxin oxidoreductase)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR033412|refseq:WP_010882382.1|ensemblbacteria:AAC65895(transcript)|ensemblbacteria:AGN76104(transcript)|ensemblbacteria:TP_0939(gene)|ensemblbacteria:TPANIC_0939(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016903"(oxidoreductase activity, acting on the aldehyde or oxo group of donors)|go:"GO:0022900"(electron transport chain)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR037112 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0939|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2Y7rYsHu2Szjpo0qEE+ujPY9k24243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:C889DEF621760138|rigid:UldjFpAN04CQIfTjr49y9zMnM1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83986 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599273|imex:IM-9152-2669 author score:0.450797616 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:F171E9895C51454F|rigid:WJdwM9Mb+isRF+4hYCsnisRFMPY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83213 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599291|imex:IM-9152-2672 author score:0.411205684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:FEE638FAEB5A2D1E|rigid:KFBa4zGTMiICcIOgiiXIsMeHzeQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83213 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599279|imex:IM-9152-2670 author score:0.430891214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:9D3FE457E37D8B0C|rigid:FxO4UToolkEGfGs9N+zg4/LT4qc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83213 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599285|imex:IM-9152-2671 author score:0.411205684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:5C6B8A137EAD44EE|rigid:RaeZF4pSzONdaYEVeYG9+xPg0V8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83738 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599297|imex:IM-9152-240 author score:0.306471946 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:D76D91C41520A7C9|rigid:ClaBucsyyErJZVNTA/foE3arBY4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83213 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599303|imex:IM-9152-241 author score:0.127807271 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:65E95D137D713767|rigid:RaZvudsjrNv2MK7ltdDEG1KiSvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83927 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599309|imex:IM-9152-242 author score:0.108230516 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:DB0FA3F298C83CC1|rigid:XiS294u6lQceSPgt2Wk0gZPjza8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83213 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599315|imex:IM-9152-243 author score:0.056843589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:250BA3893A04793F|rigid:fLlCVpFqemtb2A3jnRSI8b+9QTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83213 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599321|imex:IM-9152-244 author score:0.051338134 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:A6D4F8FD76422ED4|rigid:Ksm8hH0igpqOfBlj4eaYrULJedI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83767 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599327|imex:IM-9152-245 author score:0.03225726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0F4D7344D25C909E|rigid:ZI4+HI0Gp7Il5HF7fMM3A0u9sqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83213 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599333|imex:IM-9152-246 author score:0.010932261 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:408223A14B00E2D9|rigid:ELhvWSt4yPCFwJwgOPRjhXtmlSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83213 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599339|imex:IM-9152-247 author score:0.009071525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:E1AD179D7CB133CA|rigid:pRuOEdLg8fCgxuN+0Ry2OBa8p4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83213 uniprotkb:O83958 intact:EBI-1589991|ensemblbacteria:AAC65196 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599345|imex:IM-9152-248 author score:0.000541643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0183; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6ACABB2EDEB1858B|rigid:tr8EK7RjjWJSdMNvtjOAtojJMlc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83685 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1599355|ensemblbacteria:AAC65655 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599351|imex:IM-9152-249 author score:0.51291974 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 intact-crc:286966C350BA5B66|rigid:vFKOFNZzP1ehpfy9/r9Px3BR2gk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:O83305 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599360|imex:IM-9152-250 author score:0.319518858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:EDAD829F3C75EADB|rigid:SHArmNMnGFE6Bl4dQd3dj7O5Ivo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:P21992 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599366|imex:IM-9152-251 author score:0.23869982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:55E71424890407C8|rigid:km2aieIdEUMmpi12F3cJt494SYE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83685 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1599355|ensemblbacteria:AAC65655 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599372|imex:IM-9152-252 author score:0.215103369 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 intact-crc:9672FCA654CA63B5|rigid:8OwfIgBTwtrmapV/YaigrRYUz3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83685 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1599355|ensemblbacteria:AAC65655 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599378|imex:IM-9152-253 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 intact-crc:19D9A71162C63D70|rigid:0MO68Wtavzp5yiPPHb/6Ys1rqCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:O83667 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599384|imex:IM-9152-254 author score:0.101298891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C2322B13C123487B|rigid:d4X3WE2j7GSdzfbANWq9FF4r2fM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:O83767 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599390|imex:IM-9152-255 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:B7E567116801629F|rigid:BTdzGNXitpYK1SfswJD6YNqj3Ig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83685 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1599355|ensemblbacteria:AAC65655 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599396|imex:IM-9152-256 author score:0.058680811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 intact-crc:599A1ACB4C3EE2F1|rigid:T2LXUiqNrVyM6UXFOhlf7G9LiqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:O83954 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599402|imex:IM-9152-257 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:24714F3830568749|rigid:jKFPn3LfW2QV4QCjZu7moDdAQsE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83685 uniprotkb:O83958 intact:EBI-1599355|ensemblbacteria:AAC65655 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y679_trepa(display_long)|uniprotkb:TP_0679(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599408|imex:IM-9152-258 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882124.1|ensemblbacteria:AAC65655(transcript)|ensemblbacteria:TP_0679(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0679; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f1i1PpNLKykik35YzKJx7z30Z2I243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:A3E5313F9A1CF51D|rigid:A2URW/rI0hDUSWdF6akVUNbsSJs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1599418 uniprotkb:O83970 - intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599414|imex:IM-9152-259 author score:0.508270364 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0866; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:60E72B6B3E1F05B1 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 intact:EBI-1599418 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 - psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599421|imex:IM-9152-260 author score:0.287163122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 - psi-mi:"MI:0469"(intact) - no-uniprot-update: author-identifiers:BAIT protein TP_0866; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 - intact-crc:37E8ACAD81E32349 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1599418 uniprotkb:O83877 - intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599427|imex:IM-9152-261 author score:0.14883104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0866; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:E3676E43B4FC1C1C false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1599418 uniprotkb:O83282 - intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599433|imex:IM-9152-262 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0866; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:5096AA3BA50B1A7F false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1599418 uniprotkb:O83954 - intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599439|imex:IM-9152-263 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) no-uniprot-update: - author-identifiers:BAIT protein TP_0866; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 - rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:FFFB1567264B80CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 intact:EBI-1599418 intact:EBI-1581658|ensemblbacteria:AAC65949 - psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:tp_0866(display_short)|psi-mi:EBI-1599418(display_long) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599445|imex:IM-9152-264 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 - psi-mi:"MI:0469"(intact) - no-uniprot-update: author-identifiers:BAIT protein TP_0866; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 - intact-crc:7F4AE55C8675982F false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83752 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599451|imex:IM-9152-265 author score:0.506032515 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:7CC6F6BCFCB49ED7|rigid:eUBOGpXN7Z/i56HMFtGIHAROgn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83459 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599469|imex:IM-9152-268 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:8CB4432D0CC117ED|rigid:Jve3f9vO67zXL60IbLvw32Z/aRc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83785 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599457|imex:IM-9152-266 author score:0.499831323 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:3843A13A032D0443|rigid:LI1WaS3hOMcyXkzNpteh0jAKiGY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83627 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599463|imex:IM-9152-267 author score:0.439552849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:FE737FF19AD7FB67|rigid:6izBlfirRb0almbIC8MQzvh+Ywg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83970 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599475|imex:IM-9152-269 author score:0.393458678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:C517259DCDA2F0DE|rigid:CIR0u/bvJ7/ZXecpBmsZFM/wIKc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83670 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599481|imex:IM-9152-270 author score:0.374677525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:BD5DB17EDE491256|rigid:eMXvr/W5QnAca78tPx9d52cdanc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83709 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599487|imex:IM-9152-271 author score:0.302531602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:4CEF1BB4276E6D6A|rigid:5BmkkkEoSiCExCTPlQKUNRU/ros false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83785 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599493|imex:IM-9152-272 author score:0.274903655 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:B389E8F8C6E735F9|rigid:PujOTGamlVv1GTJorQd+RwZW9Vw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83785 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599499|imex:IM-9152-273 author score:0.249599038 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:72C9D2F0469EF435|rigid:tHu9uHKuFCOrAkaeBdF6oMjlWIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83785 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599505|imex:IM-9152-274 author score:0.210838919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:C6233F76A1EB77B5|rigid:2O7OVND2jzLb+kRAjFU3jFjTmmw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83785 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599511|imex:IM-9152-275 author score:0.206394269 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:D9F197FF0F3ACDBA|rigid:3PspeRqYa/2E/oz4yva6IQ+e/oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83785 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599517|imex:IM-9152-276 author score:0.134898342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:19662713910CF467|rigid:zXxydH8lR07J1lmS62j9VzXBOqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83785 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599523|imex:IM-9152-277 author score:0.129773569 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:21601EAA948E7B4C|rigid:hOufiDV0qoqKXhKKjiyJ+T0Vl8c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83785 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599529|imex:IM-9152-278 author score:0.06500969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:A5F91DEE2C5863EF|rigid:/CgguZ2bl+PZOfRu4A/BnQIbKbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83667 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599535|imex:IM-9152-279 author score:0.060269483 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B0A4BFA93E91A08E|rigid:f6cCQUilMN6qvK8pA8YFb1cp4uA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83785 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599547|imex:IM-9152-281 author score:0.01400239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:298B2949EF9AA914|rigid:D18t40i2jd4XgCYYI9o2d4sHkPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83785 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599541|imex:IM-9152-280 author score:0.04106747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:D2A1D07CE276C39E|rigid:+F3/xmhuGIVzMad0lkoLwPKmULs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83954 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599553|imex:IM-9152-282 author score:0.011625241 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1DC9D7C9243C8CC7|rigid:fJrFi+MDUeFOordN47pOcU7an20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83785 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584132|ensemblbacteria:AAC65776 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599559|imex:IM-9152-283 author score:0.000695806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0807; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 intact-crc:758B4A47B3456EEE|rigid:rXk+betSd7QR9gxuqOy5aK+88EQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27771 uniprotkb:O83516 intact:EBI-1593360|uniprotkb:O83775|ensemblbacteria:AAC65760 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:p5cr_trepa(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:TP_0797(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599565|imex:IM-9152-284 author score:0.504482702 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|ensemblbacteria:AAC65760(transcript)|ensemblbacteria:TP_0797(gene)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010882242.1|interpro:IPR029036|interpro:IPR036291 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0797|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nzwapTm7KjLpf0btHIa+PzwyOK4243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:47C20938227DBB6D|rigid:YpV9tNYZRRB837D602riIoJlVsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83475 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599574|imex:IM-9152-285 author score:0.484296132 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:96A0AA6085923478|rigid:OLsW6+Y0C4hVL4NwOqJk1JmSk1Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83516 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599586|imex:IM-9152-287 author score:0.430891214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:FF235F7952425E3B|rigid:gjnAUkEYlyOO3h6ps8dplh3TZWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83411 uniprotkb:O83516 intact:EBI-1198324|intact:EBI-1582948|ensemblbacteria:AAC65384|ensemblbacteria:AGN75590 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83411_trepa(display_long)|uniprotkb:TP_0396(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599580|imex:IM-9152-286 author score:0.437505157 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR006300(Flagellar basal-body rod protein FlgB)|refseq:WP_010881844.1|ensemblbacteria:AAC65384(transcript)|ensemblbacteria:AGN75590(transcript)|ensemblbacteria:TP_0396(gene)|ensemblbacteria:TPANIC_0396(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0396|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XfwazGT6RZa9K4zdsH7s3kKJmPo243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:1BC0796F348C51BD|rigid:s8sDDuvHosBTkvWyD2C/OIhmxz8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83516 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599598|imex:IM-9152-289 author score:0.398234135 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:DA8323EF62C8F205|rigid:jqzV82Z7LhZzy/AP9ApOLrDuk/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83516 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599592|imex:IM-9152-288 author score:0.411205684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:FF4627BD9E0E15EF|rigid:4OpKhZORwUCE7lAL5zdy2v9f9Q0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83516 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599604|imex:IM-9152-290 author score:0.385403935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:C569ACB131703685|rigid:g3tNW7OajNjMr3Tqpl0qR/Bp9vE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83939 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599610|imex:IM-9152-291 author score:0.385403935 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:7D61D18CD08ECCCC|rigid:zZNXyAABQbwcgF623X72tv+XN2I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83627 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599616|imex:IM-9152-292 author score:0.379046866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:9D20C1FA337796BA|rigid:emWAZ/Ez43EUkFOu5k6AU50jZFA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83516 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599622|imex:IM-9152-293 author score:0.372731062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:033F2A48F1B40ED5|rigid:Gb9NydtKj7Vl5Jx9WSdIiR/7arI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83516 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599634|imex:IM-9152-295 author score:0.32390178 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:6707E7E4C6962D6F|rigid:RhQ4AI3yLxzXUuDjneLSm/Epm5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83738 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599640|imex:IM-9152-296 author score:0.306471946 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:74403C6AF583F6C8|rigid:4LXuxvCiKbDlyqlyyrLRxT5gP84 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83516 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599628|imex:IM-9152-294 author score:0.366458388 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:1F5F7D8423A94261|rigid:J9ifpZLFZjdArJgYgEihj0y61PA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83463 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599646|imex:IM-9152-297 author score:0.227848013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:C26914C88F74D3CA|rigid:UvF9f52GJTJCzUJnSlR8PKjSy8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83516 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599652|imex:IM-9152-298 author score:0.172145866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:187C234E2087F060|rigid:lLJ7EYdxOJNOWuVANvQYE7DKUqM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83982 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599658|imex:IM-9152-299 author score:0.168342896 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:41A00E4E28BD4E60|rigid:TEeGEsUAY+j/ogD4Q9/pPSCT9Cg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83312 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599664|imex:IM-9152-300 author score:0.127807271 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:CD58C71CDD616A3B|rigid:el3Rn5cbFYZBh2MnYF84/Xad/60 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83516 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599676|imex:IM-9152-302 author score:0.108230516 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:78220E5C786B6DC0|rigid:ripOiObxj8nVTpy9kJjKK5+VTIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83516 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599670|imex:IM-9152-301 author score:0.121924355 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:8A7ED71EB92FFDB2|rigid:cigk+XLmVxtGw5GxZIyeN1OH1WA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83667 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599688|imex:IM-9152-304 author score:0.047544104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:BDA6F989C809CDA2|rigid:IWI+ryn36KV6Neav/lmYt4SrWcE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83516 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1599569|ensemblbacteria:AAC65492 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599682|imex:IM-9152-303 author score:0.086966737 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 intact-crc:51D35D9F472DFEA1|rigid:Gb6+SiyPId82SvNu3vXCSizUGlI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83767 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599694|imex:IM-9152-305 author score:0.03225726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:142D5B647909994B|rigid:Oa8u2YradosX/6FuLM2w9tb1bPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83516 uniprotkb:O83954 intact:EBI-1599569|ensemblbacteria:AAC65492 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y503_trepa(display_long)|uniprotkb:TP_0503(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599700|imex:IM-9152-306 author score:0.009071525 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881952.1|ensemblbacteria:AAC65492(transcript)|ensemblbacteria:TP_0503(gene)|go:"GO:0005886"(plasma membrane) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0503; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XIN+AffjWw5EDLSDwLZJL8x1NAg243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:4280BA339C1262CB|rigid:q/dUiL+zQpKxDIe9wwNlx6N2chU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83412 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599721|imex:IM-9152-309 author score:0.417619287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:8D7D204BA3D8DD01|rigid:jVbp7+WauUNxeDzc8oSeh7Bpo8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83542 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599715|imex:IM-9152-308 author score:0.457349077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:245C9E957C1E00DA|rigid:Wp+PjIcTuK7CmQ6mFANKz3QYIDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83634 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599709|imex:IM-9152-307 author score:0.504359397 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:8E1EC81EE1EDB221|rigid:5nNnlADTu42qzkiD41V2CdUknAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83468 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599733|imex:IM-9152-311 author score:0.404584441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:ABF1ED2A53488D76|rigid:zM+xiXTxx+XlxofGZPBoyL/qKuE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83468 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599727|imex:IM-9152-310 author score:0.411086264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:1CF06FD08E49047A|rigid:ILLc6CVmQUCdK/icZdGoKNYTmMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83468 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599739|imex:IM-9152-312 author score:0.366343877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:513F6B473FE76301|rigid:TWaWgc1Vt5LxCrpFB1epK0V613g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83463 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599745|imex:IM-9152-313 author score:0.262592252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:65E1444DBB77E060|rigid:QDtwvRPTwLXY3CJquC2stI29DRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83398 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599751|imex:IM-9152-314 author score:0.196320315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:9239D8570F0DEFA5|rigid:5+oxaa74igONi6G35iWdRD/znng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83982 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599757|imex:IM-9152-315 author score:0.196320315 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:9677FBA8E3593723|rigid:/jlbjbyKT3ZqVU3VLSWgZc9zK9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83531 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599763|imex:IM-9152-316 author score:0.175945036 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:F4E0239DD0440EB5|rigid:+s/uvNBo23ikAta5NnXyQAbTAHA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83468 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599781|imex:IM-9152-319 author score:0.143518612 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:9FB07FDD8EDC67AB|rigid:+vu/BYFw2bPQLxO9FcnQpEW2NPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83468 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599775|imex:IM-9152-318 author score:0.146859815 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:CB9FD20A66F1CC06|rigid:I3eTnqVHlKkHQX6ORd0HLTMhLTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83468 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599769|imex:IM-9152-317 author score:0.160871832 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:59B3880500D93054|rigid:srvA6lAIjNTnJmLDUyA6mHEWxLI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83877 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599793|imex:IM-9152-321 author score:0.0678013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C6867321D6A284F1|rigid:eo8zgEG1MZCUIRO+kTddlJZrTgM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83574 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599787|imex:IM-9152-320 author score:0.103096528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:39ED8C3E2BB836AF|rigid:8l6C/RID+OO/6PtJt1aGNEoETbI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83468 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599799|imex:IM-9152-322 author score:0.061303543 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:2F4F2B8780A6E6E8|rigid:C76mNIGNtM5/JeBuZZ/Gldr+ct4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83468 uniprotkb:O83767 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599805|imex:IM-9152-323 author score:0.038669797 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:9DA7C89C7FACD89B|rigid:PnHJfF7IaTE5yRNcM+8bfWkoNKE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83468 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599823|imex:IM-9152-326 author score:0.000653576 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:9E1033FC24AEA98A|rigid:vA2/7R8hUB4KOWoEpzC38JAP30o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83468 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599817|imex:IM-9152-325 author score:0.010926929 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:981702F21ABC626A|rigid:RIDZvbrUtxzPsrhdeAbcrg7y+l8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83468 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1599706|ensemblbacteria:AAC65440|ensemblbacteria:AGN75649 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83468_trepa(display_long)|uniprotkb:TP_0455(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599811|imex:IM-9152-324 author score:0.013163187 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65440(transcript)|ensemblbacteria:AGN75649(transcript)|ensemblbacteria:TP_0455(gene)|ensemblbacteria:TPANIC_0455(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0455; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:fSmXYYw+0JrjLnmUkyqMEQYGToo243276 intact-crc:51B4484706A18C89|rigid:tjwESM/Q7Mj5DQTMtAJw/cDzVsQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83787 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1599829|ensemblbacteria:AAC65778 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599839|imex:IM-9152-328 author score:0.371829559 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 intact-crc:86137F5801482672|rigid:BIWoXwXvGRVgyNwlBsjDpegESXg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83787 uniprotkb:O83709 intact:EBI-1599829|ensemblbacteria:AAC65778 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599833|imex:IM-9152-327 author score:0.494810066 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:8A2903DE2FB9A062|rigid:S09AeFEm0KnfxlKoDmRacGFm2tk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83787 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1599829|ensemblbacteria:AAC65778 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599845|imex:IM-9152-329 author score:0.260414641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 intact-crc:F083987537255178|rigid:91Zh00r8OxK4C6Ln+mVyAb41r20 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83787 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1599829|ensemblbacteria:AAC65778 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599851|imex:IM-9152-330 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 intact-crc:38C123762635A86E|rigid:+YYuioUEjYIlFmJSiNPbf/7rgl4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83787 uniprotkb:O83667 intact:EBI-1599829|ensemblbacteria:AAC65778 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599857|imex:IM-9152-331 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:EE2F85643F12373C|rigid:o2/86WuCnNuy8Gn2wZBSjA8ps8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83787 uniprotkb:O83954 intact:EBI-1599829|ensemblbacteria:AAC65778 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:rnc_trepa(display_long)|uniprotkb:rnc(gene name)|psi-mi:rnc(display_short)|uniprotkb:Ribonuclease III(gene name synonym)|uniprotkb:TP_0809(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599863|imex:IM-9152-332 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR000999(Ribonuclease III)|interpro:IPR011907(Ribonuclease III, bacterial)|refseq:WP_010882254.1|ensemblbacteria:AAC65778(transcript)|ensemblbacteria:TP_0809(gene)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR036389 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0809; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LNshL3RXRPLIbp+tQC5fi9f/LjE243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:2EB6B3BBC34CEA2D|rigid:f3Xci3xYSPN5vN3xQ5YFekht6S8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83412 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599878|imex:IM-9152-334 author score:0.432931776 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 intact-crc:710CDE7CF14D8409|rigid:JDi6FoWO2eiv2D+ySTMDqKdzrrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83595 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599872|imex:IM-9152-333 author score:0.493101142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:B5E72F0CB6BEDF65|rigid:x0EUvKl0rQMprkFFIJtSlOputNw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83470 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599884|imex:IM-9152-335 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:114B69A3FAE82530|rigid:wi4KoxPYjyVsVJGIaEngeLnWzdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83470 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599890|imex:IM-9152-336 author score:0.274903655 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:1DE3D26B114FD039|rigid:+pyPxN8TgS9NcmllM+X7EMCH9Kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83470 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599896|imex:IM-9152-337 author score:0.210838919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:684905E576439275|rigid:kSmE/t5IaxbRJwlfr2At+jb77BU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83982 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599908|imex:IM-9152-339 author score:0.206394269 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:17355A86904CFD75|rigid:mvWMaS618ZmyOaObDXdqYATLvPI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83470 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599902|imex:IM-9152-338 author score:0.206394269 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:0C87E35DBB6BE802|rigid:If6u/+/HmOLSKujyj85Ji5VOQ8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83969 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599920|imex:IM-9152-341 author score:0.169510447 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:90743E56B8C970F2|rigid:Is6TOUjYax7D7g8x+Kv8dYj1rTw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83531 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599914|imex:IM-9152-340 author score:0.185214407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:067D3DFE14E6F7B6|rigid:5pPIJfLD2H82+miGLIj0KzzaT9s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83470 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599926|imex:IM-9152-342 author score:0.154884883 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:E72C2D7249D3EFAC|rigid:LwdHbEO5c0GTXMuwLG6BB9omlac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83470 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599932|imex:IM-9152-343 author score:0.151393502 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:D913D5B0F47B6CDC|rigid:9ct6ywahtsG1H/kMBsd9ArqweH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83470 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599938|imex:IM-9152-344 author score:0.134898342 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:D7A2EA6A0E7AC4A8|rigid:nJGB4U6ycFN9pojnL/BbJX2dIAE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83470 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599944|imex:IM-9152-345 author score:0.071870197 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:7ACCFB4C4393BD82|rigid:dcdGqMXZer6gUdZ+5Fc/YtuBCFE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83413 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599950|imex:IM-9152-346 author score:0.06500969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:7484F57981B1A637|rigid:Ry3VtXN7ZRADlKTM9DCd3kD3EBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83470 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599956|imex:IM-9152-347 author score:0.04106747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:E4BEAC3EB2A571C9|rigid:zazkqgqBIZifYm4eL6jnn2q6JC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83470 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599962|imex:IM-9152-348 author score:0.034255184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:62ECA5723CE1BA22|rigid:mXhdfwEcixUTLWIGo0agdFcKn2M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83470 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599968|imex:IM-9152-349 author score:0.01400239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 intact-crc:F8F6C1DE42736CCC|rigid:0W3Tr8kwALagTNSahM+btEa+5Y8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83958 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599980|imex:IM-9152-351 author score:0.000695806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BB4F873E2C335E21|rigid:R9gt5KZpP2Znkftkq7ekkXc3EBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83470 uniprotkb:O83954 intact:EBI-1599869|ensemblbacteria:AAC65441|ensemblbacteria:AGN75651 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83470_trepa(display_long)|uniprotkb:TP_0457(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599974|imex:IM-9152-350 author score:0.011625241 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881906.1|ensemblbacteria:AAC65441(transcript)|ensemblbacteria:AGN75651(transcript)|ensemblbacteria:TP_0457(gene)|ensemblbacteria:TPANIC_0457(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0457; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:oLZBraRvCIKcqkvmLISv8l6uMOM243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:D30D1AB0BB4ABC08|rigid:Z7iKEgoQd+AY0qOdosl2mfv5fXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83312 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599995|imex:IM-9152-353 author score:0.285363151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:CB237AA675388AEE|rigid:4HBNGlr6vA2igqgye+szIyc+UZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83970 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1599989|imex:IM-9152-352 author score:0.492607984 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:3DF966C8C52F1E96|rigid:m+gaPcm2chxIoy7hrZEy74MrAKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83413 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600001|imex:IM-9152-354 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:71BAE2E9A875F373|rigid:5R/tlh2e6av3MerffdyjFJMQH+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83667 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600007|imex:IM-9152-700 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:5672C5588824A02D|rigid:Ry8nPUWwri4ctuxrndrnsLD9wEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83745 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600013|imex:IM-9152-1293 author score:0.06996641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:202BE807735BE555|rigid:gttg0f2RYNgwPqeMEmhJQcp3ULI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83282 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600019|imex:IM-9152-1294 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:3D3D1386FB9A5C26|rigid:iuCUkndJNqHY87YiiMZx26JkVtw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83602 uniprotkb:O83970 intact:EBI-1600031|ensemblbacteria:AAC65571 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600034|imex:IM-9152-1296 author score:0.492607984 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:6E2CDBCFB173A0DC|rigid:+kwwn5w2p4Mqtq5ZNmOkAAW+w9w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83389 uniprotkb:O83958 intact:EBI-1599986|ensemblbacteria:AAC65362 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y374_trepa(display_long)|uniprotkb:TP_0374(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600025|imex:IM-9152-1295 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881822.1|ensemblbacteria:AAC65362(transcript)|ensemblbacteria:TP_0374(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0374; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bknYYt5QKtkeLQ+sfXLQO+nDreM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:0350859340659841|rigid:u70CiuKDSSsKKYfWB07SJshnVF8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83602 uniprotkb:O83982 intact:EBI-1600031|ensemblbacteria:AAC65571 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600040|imex:IM-9152-1297 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:E27BCC3DF8421E72|rigid:gYupo3/HmxLkk/tKHACR3VLeeK8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83602 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1600031|ensemblbacteria:AAC65571 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600046|imex:IM-9152-1298 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 intact-crc:381304D8B4EB005D|rigid:MdjklTGG6nRb2TyjFjbZeBYxKNg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83602 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1600031|ensemblbacteria:AAC65571 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600052|imex:IM-9152-1299 author score:0.141067282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 intact-crc:18DEE324E7C1ED2E|rigid:uml80jyma224TQaxR0wH+JshVKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83602 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1600031|ensemblbacteria:AAC65571 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600058|imex:IM-9152-1300 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 intact-crc:8E3BE7658B05A01E|rigid:iRwYqhTVgEibwdyRLySYu/l5Z+8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83602 uniprotkb:O83954 intact:EBI-1600031|ensemblbacteria:AAC65571 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600064|imex:IM-9152-1301 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:25974B01D6F497CF|rigid:/dilkwSFQFsuhkTnC6B4TA2VTYI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83123 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600079|imex:IM-9152-1303 author score:0.490317105 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:2CDBD477E8782BC7|rigid:6UyQ2zr+irCG1JxDhof3aHJ9E2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83602 uniprotkb:O83958 intact:EBI-1600031|ensemblbacteria:AAC65571 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y593_trepa(display_long)|uniprotkb:TP_0593(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600070|imex:IM-9152-1302 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882039.1|ensemblbacteria:AAC65571(transcript)|ensemblbacteria:TP_0593(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0593; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z7KNxiwBfuX4+95JoWqNFavz6IY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:508538943439260B|rigid:mD0l1JL6E2H0JrZeUMuspqeJsJ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83123 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600091|imex:IM-9152-1305 author score:0.459536293 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:1593A18E67C4B6C9|rigid:tMMxqw3flwZiEIbZgFLq3HaewMU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83123 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600085|imex:IM-9152-1304 author score:0.463521187 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:A6F641782AE0EFCD|rigid:lv4gyzMLxGjl+qcwuMX+PCqUxbo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83123 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600097|imex:IM-9152-1306 author score:0.426334568 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:2B91C845D0F60AD9|rigid:ysMOFub8fuRUqOMy6lJc3/6QreA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83311 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600103|imex:IM-9152-1307 author score:0.419763476 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:574D7CEECCC4759C|rigid:IsKhmfeU32v/K3yxdWcw+26jkE4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83123 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600115|imex:IM-9152-1309 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:128BDF8F08DB3CE7|rigid:oGQqkGYGN8NlhH4pt+XkvXIDDqk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83459 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600109|imex:IM-9152-1308 author score:0.400228804 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:37F1910B907809BB|rigid:k+gE5trARauzC0YUS5zfH6uohvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83305 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600127|imex:IM-9152-1311 author score:0.210838919 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:F70C1F187EB4A327|rigid:CuxSHn10k5rqzQb6HaKQp0NRO24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83123 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600121|imex:IM-9152-1310 author score:0.302531602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:244B8A6426323139|rigid:whRczki+O3xQGDkeowrjVS+0RLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83398 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600133|imex:IM-9152-1312 author score:0.206394269 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:FB72A8D1C1C95CE3|rigid:D8kchJfr4W7nxKlbjFPi1id8Z1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83123 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600139|imex:IM-9152-1313 author score:0.206394269 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:14F5ECAA627FE4A2|rigid:rD7NxStzO7KBwRXspqNi7NKm/lo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83123 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600145|imex:IM-9152-1314 author score:0.196974308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:F0D3EAB7737E1AC5|rigid:46UpV49tYXLSPffyxEAwUBAmD04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83531 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600151|imex:IM-9152-1315 author score:0.185214407 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:05BD8BD2E6D5EE61|rigid:M6b9Ujuevaz/skcu2Geo7Tdg1i4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83413 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600157|imex:IM-9152-1316 author score:0.06500969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:3A54C45A04986E04|rigid:O3CCYW+J/K4Cw3rMnlv0exy8Otc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83123 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600163|imex:IM-9152-1317 author score:0.049179154 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:3A1E88AAFA0C59E2|rigid:2uPyy+g5eahrHRjtSkiXVJ9+t0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83954 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600181|imex:IM-9152-1320 author score:0.011625241 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:D0CDAC9C4979A5DF|rigid:va2TfwTjKLw9VV01pkWDXBWUH78 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83123 uniprotkb:O83282 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600175|imex:IM-9152-1319 author score:0.01400239 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:39C54018F14A0992|rigid:jnOrHa5/l3SYjTaENRiXE8yRBi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83123 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600169|imex:IM-9152-1318 author score:0.04106747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:41A2760E8CBAA9C2|rigid:UaMfAmXglSpFUwtTtpGh6fgfhE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83864 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600193|imex:IM-9152-1322 author score:0.481973032 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 intact-crc:93623460A6293FA5|rigid:1QAXcRZm75me4hGGe7O+KigycRs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83123 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1600076|ensemblbacteria:AAC65080|ensemblbacteria:AGN75304 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83123_trepa(display_long)|uniprotkb:TP_0085(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600187|imex:IM-9152-1321 author score:0.000695806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR002178(Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2)|refseq:WP_010881534.1|ensemblbacteria:AAC65080(transcript)|ensemblbacteria:AGN75304(transcript)|ensemblbacteria:TP_0085(gene)|ensemblbacteria:TPANIC_0085(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0085; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:0Db7o+7YqTEIBUv4nNGgP2XhaFU243276 intact-crc:B88F3112DE0047F6|rigid:nhM04ldcLCNC4QLQQtdq4XuJVyY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83596 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600199|imex:IM-9152-1323 author score:0.415478208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:BDB4D379C00580EB|rigid:CQAapRV85GSQBbAObB/r/dvV+aU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83570 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600205|imex:IM-9152-1324 author score:0.396006855 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:14A6E9FC38316462|rigid:HoGCKUANKA/y8oyYrTR54JEfBq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83311 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600211|imex:IM-9152-1325 author score:0.389585756 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:926BA549824B3156|rigid:FFX4Ef2rdjfBi8Qyma2qMGPWL/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83056 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600223|imex:IM-9152-1327 author score:0.370558584 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:50AB48CA741BA008|rigid:qQRiKcWF/azHSy36UGcUhwqsZpk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83752 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600229|imex:IM-9152-1328 author score:0.370558584 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:B275D17EC450F677|rigid:bQbTCunqeX3B2M6Z4G+RVjZ6RlM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83459 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600217|imex:IM-9152-1326 author score:0.370558584 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:970F9FFA5CF3C32B|rigid:DhNeUGO1WsOF4UiHZLKn3Y7vmI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83056 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600235|imex:IM-9152-1329 author score:0.345809367 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:EA6E9C1B53E01CC1|rigid:Mo878x+Y2W2UzSr6BLln1ZWOAog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83709 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600241|imex:IM-9152-1330 author score:0.276761915 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:E41F47E81B169B1D|rigid:oBwfF2d8O8flbSNjBtg6f5O7L1E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83463 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600247|imex:IM-9152-1331 author score:0.250641622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:C7FA2DE401D5B084|rigid:SzmmJLOxu3prn80JTOEx13cA5M8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83305 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600253|imex:IM-9152-1332 author score:0.190743641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:7A946F11179DEA79|rigid:K5z15kq8HwKzGuFZlvT35hwA/S0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83531 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600265|imex:IM-9152-1334 author score:0.167044459 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:4B5C5B6B6BCA8A35|rigid:e9+TcQyxV87L+qTzYXwbGch7/1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83056 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600259|imex:IM-9152-1333 author score:0.186622436 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:70940C422C7F1684|rigid:z5/5ZCOaq7F7nSvu+jCS5Ya6AQI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83056 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600277|imex:IM-9152-1336 author score:0.063946891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:B372ED4E84C9DFA9|rigid:CUsnGQi3vTLYCJEq12Fr1CNNmsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83969 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600271|imex:IM-9152-1335 author score:0.15259257 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:46961821BD070159|rigid:T0a9KAlZv/zpjf/oqH5Aw26jCTg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83667 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600283|imex:IM-9152-1337 author score:0.053551303 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:3417C04B1A8DA356|rigid:RhH90/Ge2hDIStPjwMp60ak0ENc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83056 uniprotkb:O83767 intact:EBI-1582638|ensemblbacteria:AAC65012 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600289|imex:IM-9152-1338 author score:0.036406795 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:64207A4C6F039AFB|rigid:XUaeES6dtZzK7P+1o2yl0YU/PDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83056 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600301|imex:IM-9152-1340 author score:0.012373649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:926B2ACCBB0E15E2|rigid:7wwr9b01nrLMbhfsPZuOk+q67cA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83056 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600295|imex:IM-9152-1339 author score:0.03034316 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:9DD92577D3DB9269|rigid:E82ClEHeuymmxBuRUxYdABXZl3s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83056 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600307|imex:IM-9152-1341 author score:0.010270127 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:79FEC234F8A82B93|rigid:+MWd75T0RaOvi5rUOy/A2CJ/DP4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83130 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600319|imex:IM-9152-1343 author score:0.471952334 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:84996FE82B1B32A8|rigid:C9Lfv71agsDkahGqdBCf2YSZ+R0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83056 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582638|ensemblbacteria:AAC65012 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y012_trepa(display_long)|uniprotkb:TP_0012(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600313|imex:IM-9152-1342 author score:0.000613907 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65012(transcript)|ensemblbacteria:TP_0012(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0012; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:FKAaFOAMRO2AyN+z+IuOcEizjpg243276 intact-crc:2D983949A1F99AA4|rigid:rQg+1Rxh2ViFLy6svP5KZnW6Nzw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83099 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600325|imex:IM-9152-1344 author score:0.458182508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:E475F7D41E23F4D0|rigid:OvKGlibW54aH6NC3d/9w20ExllI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83130 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600331|imex:IM-9152-1345 author score:0.285363151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:5C1D1472E3D603A7|rigid:/d7hNglR3Iv3s1c3vpVLoHDZGKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83745 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600337|imex:IM-9152-1346 author score:0.134100424 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:A267F3724BC3E5D8|rigid:8I2fE8h4zunVXdl4wHB3+QxjBy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83130 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600343|imex:IM-9152-1347 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:72D381BDEA53CE7E|rigid:wF3xM6hTx8cN4eGKHJCmZwAHovE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83130 uniprotkb:O83282 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600349|imex:IM-9152-1348 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:50AD3E6CF9BD4906|rigid:46iCNI+l+ibY99AN/FF5lP5X7B8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83349 uniprotkb:O83282 intact:EBI-1600365|ensemblbacteria:AAC65317 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:glya_trepa(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:TP_0329(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600361|imex:IM-9152-1350 author score:0.468791231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|ensemblbacteria:AAC65317(transcript)|ensemblbacteria:TP_0329(gene)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|interpro:IPR039429 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0329|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LFMwg5Gy2bjW5KbUHE/f9otRy6M243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:ADB003C19E31E1F3|rigid:d8Prgz1MfA7fJyEYGlGSt/b4jyc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83130 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600355|imex:IM-9152-1349 author score:0.001877487 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0092; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:D1D3BA34D15344AA|rigid:+I+W7QS3zUZz62uivHdgesGt3WY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83679 uniprotkb:O83282 intact:EBI-1600371|ensemblbacteria:AAC26571 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:sye_trepa(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0673(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600375|imex:IM-9152-1351 author score:0.468791231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033910|refseq:WP_010882118.1|ensemblbacteria:AAC26571(transcript)|ensemblbacteria:TP_0673(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|interpro:IPR020752 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0673|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nvqK5EgGT4yJnD2HYec4tPrUj0c243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:4A7BF14AD1C68011|rigid:s3JijBTGJQwtMi8flVYrEY32Odk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83361 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600381|imex:IM-9152-1352 author score:0.39624284 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:3F8C0E42DD6A5B30|rigid:SEXvGz79hexE27bz2JBOqeKx4tI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83282 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600387|imex:IM-9152-1353 author score:0.377091391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:2B3A31591D325C7C|rigid:JlW2RC0Lvvij/+TdzOgrK+l3Ess false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83098 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600393|imex:IM-9152-1354 author score:0.339965696 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:20B91EF70BDF408C|rigid:74Us0+DEtLem7GvmF+myhMtXbTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83459 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600405|imex:IM-9152-1356 author score:0.287870433 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:226A6C89461A375A|rigid:u9AM1goNtL8B1dxSKE9sVu1VXYc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83570 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600399|imex:IM-9152-1355 author score:0.310440769 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:23AC29BEAEB1F5A9|rigid:1SbrRmbs/HtIN1kmjDCoIZgqvDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83282 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600411|imex:IM-9152-1357 author score:0.287870433 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:0710220DDEB90206|rigid:E2yZgGcMZxitmbJlgTogkUvzoCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83565 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600417|imex:IM-9152-1358 author score:0.271600623 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:EBDA300D1094C2D8|rigid:Vc3ElB6PYkhgfKUyUsXLsGiiMss false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83282 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600423|imex:IM-9152-1359 author score:0.266307318 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:AD983D2F3DB6B6EE|rigid:Y/dOzYJYDzkWa2QLnRiaZ8SuCgE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83709 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600435|imex:IM-9152-1361 author score:0.20808474 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:19C65610DE590D4F|rigid:SAtHwHJBmYrjeEcmUUZGOFQJlK4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83970 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600429|imex:IM-9152-1360 author score:0.217097086 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:5D1ED4C3A100E8CC|rigid:9lk6GOZYqMemyFCQFPZwNIq1WmE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83282 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600441|imex:IM-9152-1362 author score:0.186772231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8250CF69CD587E51|rigid:KkF8W0TP9q1flZYcTdesYdhtSZY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83282 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600447|imex:IM-9152-1363 author score:0.139300308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:E6B580ABE79F47E3|rigid:dwirfpV4T5OcZUGdVmCCCtFhfNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83398 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600453|imex:IM-9152-1364 author score:0.136103654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:1A83E82949D0C7B2|rigid:3IScY6lhe3ivbTJj8RqFkjpKyDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83282 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600465|imex:IM-9152-1366 author score:0.110039438 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:D4543D2A3ABBE230|rigid:tO1l9PnrHBXiokR4vZ/NsRl8vOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83282 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600459|imex:IM-9152-1365 author score:0.136103654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:F504AC52EA667FF3|rigid:S7lZRrCcC20S2XHrU7iFN3+Rlbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:P21992 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600477|imex:IM-9152-1368 author score:0.097532176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:68E3C6A18EE82D3D|rigid:GnwfeTSzot4HDaviwxD/U3aYPcw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83099 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600471|imex:IM-9152-1367 author score:0.099927695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:3B41C10F38B00138|rigid:/0IQpKniWBiMRXq1irr0O9SB2+g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83282 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600483|imex:IM-9152-1369 author score:0.069018465 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:91DFF663B537ABEE|rigid:dG9eQ854Oiv9b5FqXfoHTo9y1NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83877 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600489|imex:IM-9152-1370 author score:0.044807068 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:FBA41946141381D9|rigid:X5rpdH2OMDwPIg82cNXLZCOj6og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83413 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600495|imex:IM-9152-1371 author score:0.040417425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:5F84AE9F117D0356|rigid:sapvGgW8kUWPPQQaN0GOhJJFDUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83282 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600501|imex:IM-9152-1372 author score:0.037398649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:FD085911CF1540EC|rigid:dFRKE/Q6aAckM+yZOQXNJZJlTGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83282 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600513|imex:IM-9152-1374 author score:0.008529458 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:444EE05EAA164260|rigid:MHbIGRietprT1qnWGHd+N0dWaUY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83767 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600507|imex:IM-9152-1373 author score:0.025287264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:03F4D57A49340954|rigid:YsgnCLEYZR0WGMOqDbe56hFON+k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83282 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600525|imex:IM-9152-1376 author score:0.000421622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:86563157BA7114F1|rigid:NLQdY3FQy5eFHe51/Ww+eocSyDo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83282 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600519|imex:IM-9152-1375 author score:0.007074768 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0258; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9A946F52C8E6BC80|rigid:r/Q9uqavrd9tSyNZtLQhOSxT6Ls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83059 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1600531|ensemblbacteria:AAC65007 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:syfb_trepa(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:TP_0015(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600535|imex:IM-9152-1377 author score:0.462674733 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010881464.1|ensemblbacteria:AAC65007(transcript)|ensemblbacteria:TP_0015(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR020825|interpro:IPR041616 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0015; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:OtYcOxu3X974TCRDqefIetX37Eg243276 intact-crc:92B39DB418462047|rigid:EdremNX62fjZng5/P3Bvrl2IIp4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83059 uniprotkb:O83574 intact:EBI-1600531|ensemblbacteria:AAC65007 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:syfb_trepa(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:TP_0015(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600541|imex:IM-9152-1378 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010881464.1|ensemblbacteria:AAC65007(transcript)|ensemblbacteria:TP_0015(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR020825|interpro:IPR041616 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0015; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OtYcOxu3X974TCRDqefIetX37Eg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:A998922C61C42CE6|rigid:VQiitnO1EtR4ErgXbYH7RmVXswY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83059 uniprotkb:O83958 intact:EBI-1600531|ensemblbacteria:AAC65007 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:syfb_trepa(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:TP_0015(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600559|imex:IM-9152-1381 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010881464.1|ensemblbacteria:AAC65007(transcript)|ensemblbacteria:TP_0015(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR020825|interpro:IPR041616 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0015; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OtYcOxu3X974TCRDqefIetX37Eg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:740D4B0A79EA6625|rigid:t2enQ+/RR4IX85wi2JLH1iW2sLw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83059 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1600531|ensemblbacteria:AAC65007 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:syfb_trepa(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:TP_0015(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600553|imex:IM-9152-1380 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010881464.1|ensemblbacteria:AAC65007(transcript)|ensemblbacteria:TP_0015(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR020825|interpro:IPR041616 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0015; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:OtYcOxu3X974TCRDqefIetX37Eg243276 intact-crc:FDEA240B67D08958|rigid:H42VOMyQd9N9lBxUWMP6UaaXEew false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83059 uniprotkb:O83282 intact:EBI-1600531|ensemblbacteria:AAC65007 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:syfb_trepa(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:TP_0015(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600547|imex:IM-9152-1379 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010881464.1|ensemblbacteria:AAC65007(transcript)|ensemblbacteria:TP_0015(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR020825|interpro:IPR041616 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0015; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OtYcOxu3X974TCRDqefIetX37Eg243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:113F639DF7E5AE37|rigid:r9iTErrxq5i5B3UzEiQ3fIYgwMo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83058 uniprotkb:O83574 intact:EBI-1198380|intact:EBI-1582007|ensemblbacteria:AAC65014 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y014_trepa(display_long)|uniprotkb:TP_0014(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600565|imex:IM-9152-1382 author score:0.462092867 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65014(transcript)|ensemblbacteria:TP_0014(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0014|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7rMeCmvee8WGRi8XmRFI64EGDm4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:1E9C689D1957D5A4|rigid:RNE9vp94yhLytIoGkjlEi4bFtsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83574 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600571|imex:IM-9152-1383 author score:0.442089186 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0981|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:0D984BCF647D32BE|rigid:ZKqanU794oJPv8MNU0RF7Nuf1Vg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83574 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600577|imex:IM-9152-1384 author score:0.39624284 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:BF217074C9C682E6|rigid:Rj8jIHIFG+AOL06FIpQA6H/z5T4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83986 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600583|imex:IM-9152-1385 author score:0.389820384 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:12838F80330E58C7|rigid:187ocR0A1nseKlZquFcgm5BiRxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83913 uniprotkb:O83574 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600589|imex:IM-9152-1386 author score:0.377091391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:F4A7C4078459CC06|rigid:NdrvP6TKaAzWDsO3XcmZdnWL5x8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83574 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600595|imex:IM-9152-1387 author score:0.370788714 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:BBD68DE4DA447E1D|rigid:/kwmUbOQ9iNsX6pGB554h12paAU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83574 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600601|imex:IM-9152-1388 author score:0.370788714 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:B9B261917C60CE89|rigid:FBGcsr+q0GtBbf857jfOtqz5fP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O66106 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600607|imex:IM-9152-1389 author score:0.35214996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:449076488D796D73|rigid:RLtW1mF0W8UV44KpGeqo6FOqENU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83574 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600613|imex:IM-9152-1390 author score:0.327989572 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:DE6ECB9D9347A321|rigid:83MLYCQCLJ3m92AI4+VMzW6dhgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83574 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600625|imex:IM-9152-1392 author score:0.255919891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:0738E03B501A4B2F|rigid:ybaShKJGVI8IqOk27A/F3O27Vxc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83574 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600619|imex:IM-9152-1391 author score:0.266307318 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:8951FE30EEF3518C|rigid:i7H3S3qI3IQElP+X5PoOqU8UC88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83574 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600631|imex:IM-9152-1393 author score:0.217097086 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:79D717DC72450FAE|rigid:fTxzeu6uYlSEBklDDXlQlnxh80k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83709 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600637|imex:IM-9152-1394 author score:0.20808474 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:4B479DD898B26774|rigid:lZap5HiH8IZO5gytEEU0kUlvWsI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83463 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600643|imex:IM-9152-1395 author score:0.186772231 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:16AA6D9D8280BE9B|rigid:ULs3MEEYtGihOnjrF22WvDyvb5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83398 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600649|imex:IM-9152-1396 author score:0.136103654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:C42345E98D0A1223|rigid:ut0TKRp3dVNnQ755LaQJN0In1wQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83982 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600655|imex:IM-9152-1397 author score:0.136103654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:D1CD6F4D39239891|rigid:sRXWGbyxT91xR3BbT5hsr1YOO3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83531 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600661|imex:IM-9152-1398 author score:0.121036798 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:A6ADF8E769F30707|rigid:KtPoikcMx4L8NqhyVJVjZw0SsNk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83574 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600667|imex:IM-9152-1399 author score:0.102375376 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:BEFF2D46BC7B3C62|rigid:4eGFmfkYtLH9xHtaxVRvir7mAzc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83574 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600673|imex:IM-9152-1400 author score:0.099927695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:2F6E1ED422DBE434|rigid:Tq63CiCYHBkm7p/AleTF39NLU2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83574 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600679|imex:IM-9152-1401 author score:0.097532176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:4C2A05BE5DADCA5F|rigid:wsayMmicCt49Y+WQL8Ktfui7PKI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83574 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600691|imex:IM-9152-1403 author score:0.069018465 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:B516357C66724C8C|rigid:68fm6sSfVIiUOlTEAdsgcZAQJOk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83927 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600685|imex:IM-9152-1402 author score:0.086308643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:D0FA6FC63F80E1B6|rigid:eHTJwT/G+zCDhzT/HfR6Zy6KSiM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83574 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600697|imex:IM-9152-1404 author score:0.044807068 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:DF6DDA59C75666BB|rigid:7YwI8IeekF/H5J70WERGavzY8bc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83667 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600703|imex:IM-9152-1405 author score:0.037398649 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:D9C19A0E1C50A78E|rigid:nd86oMBk5vc1ix64lPTKrIuF9f0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83574 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600709|imex:IM-9152-1406 author score:0.025287264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:273D16659A71EE36|rigid:FndKctBTJj47RO/8M3KyVpWZ/gQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83574 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600715|imex:IM-9152-1407 author score:0.008529458 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:1ECF9F6510D01C7A|rigid:dG9eQ854Oiv9b5FqXfoHTo9y1NE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83498 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600736|imex:IM-9152-1755 author score:0.434673096 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 intact-crc:1EDC164BC2B29BEC|rigid:DqYkKmDLHdxdq/eNWQi8b7GU4LI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83574 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600721|imex:IM-9152-1753 author score:0.007074768 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0563; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:BE5DAC4D1BA35BE2|rigid:eC0dpZR3e9t/Gz8LmL/oO9tpPIw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83498 uniprotkb:O83887 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 intact:EBI-1581590|ensemblbacteria:AAC65873|ensemblbacteria:AGN76084 psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:o83887_trepa(display_long)|uniprotkb:TP_0917(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600727|imex:IM-9152-1754 author score:0.459046304 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR006668(MgtE intracellular region)|interpro:IPR006667(MgtE integral membrane region)|interpro:IPR006669(Divalent cation transporter)|ensemblbacteria:AAC65873(transcript)|ensemblbacteria:AGN76084(transcript)|ensemblbacteria:TP_0917(gene)|ensemblbacteria:TPANIC_0917(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882360.1|interpro:IPR038076|interpro:IPR036739 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0917|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 rogid:6aiXfTsgUS7SLyGaGaB55agbl7w243276 intact-crc:561290C9816D8C8C|rigid:wDz+sBmyg7UEWfl8UqD5Ay9/VJ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83498 uniprotkb:O83574 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600748|imex:IM-9152-1757 author score:0.206071282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C575C2DFE0952BD7|rigid:2EJkxmtDxauadt44aGc7T7VKaSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83498 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600742|imex:IM-9152-1756 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 intact-crc:1F48C04C8E789394|rigid:TpCjOXauB52WNqWvUqYTwTUWnxI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83498 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600754|imex:IM-9152-1758 author score:0.141067282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 intact-crc:424F0AAECEE99B7E|rigid:njs3wcXusws3mI95D3UQ9AkmtOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83498 uniprotkb:O83954 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600760|imex:IM-9152-1759 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:7F06A28BFFDCE19F|rigid:drrwbf2BzbFBpS2PwsG5V+qJHLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83498 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1600731|ensemblbacteria:AAC65466|ensemblbacteria:AGN75676 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83498_trepa(display_long)|uniprotkb:TP_0485(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600766|imex:IM-9152-1760 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR029787|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|refseq:WP_010881934.1|ensemblbacteria:AAC65466(transcript)|ensemblbacteria:AGN75676(transcript)|ensemblbacteria:TP_0485(gene)|ensemblbacteria:TPANIC_0485(gene)|go:"GO:0009190"(cyclic nucleotide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0485; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:rO+av9xT2MTfvMJwXvjA0QeGKDE243276 intact-crc:0A14D11E1D11505B|rigid:jFE/1ynUfANff752NKRXe3JL134 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83881 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1199028|intact:EBI-1585205|ensemblbacteria:AAC65862|ensemblbacteria:AGN76079 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83881_trepa(display_long)|uniprotkb:TP_0911(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600772|imex:IM-9152-1761 author score:0.452124226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR029025|interpro:IPR004683(FlhB-like)|interpro:IPR006135(Type III secretion exporter)|refseq:WP_010882354.1|ensemblbacteria:AAC65862(transcript)|ensemblbacteria:AGN76079(transcript)|ensemblbacteria:TP_0911(gene)|ensemblbacteria:TPANIC_0911(gene)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0911; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:5jI5N/SVRQzQ66Jqtz9tsAS0IFg243276 intact-crc:F96ACB42F668306B|rigid:0fXpoH2UKhkyrjvR5ZHOMR1WEt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83386 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1585474|ensemblbacteria:AAC65356 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:ispe_trepa(display_long)|uniprotkb:ispE(gene name)|psi-mi:ispE(display_short)|uniprotkb:"4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase"(gene name synonym)|uniprotkb:TP_0371(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600778|imex:IM-9152-1762 author score:0.448254013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR006204(GHMP kinase)|interpro:IPR004424(4-diphosphocytidyl-2C-methyl-D-erythritol kinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65356(transcript)|ensemblbacteria:TP_0371(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0050515"("4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity")|refseq:WP_010881819.1|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0371; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:ES/0eXhZ+H0Qa/tkW2BOa7n+6pQ243276 intact-crc:D457DABF92DA8D84|rigid:x9k62ldKAEDiwiUSZtJ/2xx/Kxg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83170 uniprotkb:O83305 intact:EBI-1586597|ensemblbacteria:AAC65125 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:y134_trepa(display_long)|uniprotkb:TP_0134(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600790|imex:IM-9152-1764 author score:0.436655624 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65125(transcript)|ensemblbacteria:TP_0134(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881582.1 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0134; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Z2YYYZZu6zrWkkkuj8sTOYMJO1k243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:B733EDD90430640F|rigid:JcL830DBKUEBIVwjRQZKCaI7HyI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83386 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1585474|ensemblbacteria:AAC65356 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:ispe_trepa(display_long)|uniprotkb:ispE(gene name)|psi-mi:ispE(display_short)|uniprotkb:"4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase"(gene name synonym)|uniprotkb:TP_0371(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600784|imex:IM-9152-1763 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR006204(GHMP kinase)|interpro:IPR004424(4-diphosphocytidyl-2C-methyl-D-erythritol kinase)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65356(transcript)|ensemblbacteria:TP_0371(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0050515"("4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity")|refseq:WP_010881819.1|interpro:IPR036554 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0371; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ES/0eXhZ+H0Qa/tkW2BOa7n+6pQ243276 intact-crc:540C65EE6A71D29B|rigid:+tWNrS5F6RsY5h22Ri0hjDDzef0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83137 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600802|imex:IM-9152-1766 author score:0.430360235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0099; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 intact-crc:ACC46250D0D27684|rigid:2NKg50RPm/stI9Fa0aw2NUf38fk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83170 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1586597|ensemblbacteria:AAC65125 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y134_trepa(display_long)|uniprotkb:TP_0134(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600796|imex:IM-9152-1765 author score:0.183444879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65125(transcript)|ensemblbacteria:TP_0134(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881582.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0134; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:Z2YYYZZu6zrWkkkuj8sTOYMJO1k243276 intact-crc:7777460D12A283F6|rigid:Octkhgd208Dt3Sswohj7bCcmZCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83137 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600814|imex:IM-9152-1768 author score:0.206073073 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0099; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 intact-crc:774175C3C86CEEC0|rigid:+KoKJIKa3VvpSeEUdExyWIHuEPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83137 uniprotkb:O83305 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600808|imex:IM-9152-1767 author score:0.391095335 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0099; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:3CE76F08E5879FC0|rigid:wmwCjomwQl8jtZp7A5C6laGQSl8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83137 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600826|imex:IM-9152-1770 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0099; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 intact-crc:5FAEFCC1B1C76B3B|rigid:XtNSHzUmjIMxKEyu6IXo/lm7Bw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83391 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1600836|ensemblbacteria:AAC65381 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600832|imex:IM-9152-1771 author score:0.430286523 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 intact-crc:A255C9A5090AB48B|rigid:lMBZVv7zaadxTld3ck/x1LBxq4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83137 uniprotkb:O83745 intact:EBI-1583259|ensemblbacteria:AAC65094|ensemblbacteria:AGN75318 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83137_trepa(display_long)|uniprotkb:Uridylate kinase(gene name synonym)|uniprotkb:TP_0099(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600820|imex:IM-9152-1769 author score:0.106356811 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65094(transcript)|ensemblbacteria:AGN75318(transcript)|ensemblbacteria:TP_0099(gene)|ensemblbacteria:TPANIC_0099(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0044210"('de novo' CTP biosynthetic process)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|interpro:IPR011817(Uridylate kinase)|refseq:WP_010881548.1|interpro:IPR011818(Uridylate kinase, archaeal/spirochete, putative)|interpro:IPR036393 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0099; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PkHFBRSlxfEcxLCINfsmokSncOI243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:1720817ED0C4FDC0|rigid:o6H+7bSF1NZxSpGoyRkLZQJJ0cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83391 uniprotkb:P21992 intact:EBI-1600836|ensemblbacteria:AAC65381 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600847|imex:IM-9152-1773 author score:0.262210377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:3A78320FC59AB979|rigid:A2rmvgaeYRhLyswxJqzPs1WeboU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83391 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1600836|ensemblbacteria:AAC65381 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600841|imex:IM-9152-1772 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 intact-crc:B63C57040DCE4A9C|rigid:VgsUO4owLFsQ8uakWZwY/2oCi4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83391 uniprotkb:O83574 intact:EBI-1600836|ensemblbacteria:AAC65381 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600853|imex:IM-9152-1774 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:7611482CDBBDFDCD|rigid:r/eSBQwuIdfrF03t0DkLS9bw+ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83391 uniprotkb:O83877 intact:EBI-1600836|ensemblbacteria:AAC65381 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600859|imex:IM-9152-1775 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C1C1E720EFF51B5E|rigid:7mGowRczLhlTgKGCmjLrD0KKxlo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83391 uniprotkb:O83413 intact:EBI-1600836|ensemblbacteria:AAC65381 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600865|imex:IM-9152-1776 author score:0.121660562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:72A886ACE9CE7D48|rigid:ySQqMSJTxXRRvLZ3hwm0CzN9KWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83391 uniprotkb:O83667 intact:EBI-1600836|ensemblbacteria:AAC65381 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600871|imex:IM-9152-1777 author score:0.113290143 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:7A6D4A5E6B5C3057|rigid:B0+6qMriOM59bE1azcOvtsJha5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83391 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1600836|ensemblbacteria:AAC65381 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y376_trepa(display_long)|uniprotkb:TP_0376(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600877|imex:IM-9152-1778 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65381(transcript)|ensemblbacteria:TP_0376(gene)|refseq:WP_010881824.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0376; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:uwk8m5CYU8FFIzgIPwsPdmT3/c8243276 intact-crc:2F4AF37E43CF4BDA|rigid:lISgwjj3N8NXNSTxdlxhEu7fUsY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83240 uniprotkb:O83282 intact:EBI-1582475|ensemblbacteria:AAC65199 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:rs13_trepa(display_long)|uniprotkb:rpsM(gene name)|psi-mi:rpsM(display_short)|uniprotkb:TP_0210(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600889|imex:IM-9152-1780 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR019980|interpro:IPR018269|ensemblbacteria:AAC65199(transcript)|ensemblbacteria:TP_0210(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881658.1|interpro:IPR027437 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0210; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:lpIJO6TLBl77jH2jY17vj/fgxOc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:31AB58D5CA551CB7|rigid:K//Y2YxuZAuGizgq5G71O0SLkSA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83240 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1582475|ensemblbacteria:AAC65199 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:rs13_trepa(display_long)|uniprotkb:rpsM(gene name)|psi-mi:rpsM(display_short)|uniprotkb:TP_0210(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600883|imex:IM-9152-1779 author score:0.430044705 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR019980|interpro:IPR018269|ensemblbacteria:AAC65199(transcript)|ensemblbacteria:TP_0210(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881658.1|interpro:IPR027437 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0210; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:lpIJO6TLBl77jH2jY17vj/fgxOc243276 intact-crc:4D154D39FF08E456|rigid:or2gPq1n9IQG8DpvLFFmTvhRJto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83533 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1600899|ensemblbacteria:AAC65508|ensemblbacteria:AGN75709 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83533_trepa(display_long)|uniprotkb:TP_0521(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600904|imex:IM-9152-1782 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR027417|refseq:WP_010881969.1|ensemblbacteria:AAC65508(transcript)|ensemblbacteria:AGN75709(transcript)|ensemblbacteria:TP_0521(gene)|ensemblbacteria:TPANIC_0521(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0521; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:+PNQP6QJzEp9m1aFpHYEcYrHSjc243276 intact-crc:023331A5F67F771B|rigid:JU6p0U/MI77gO0YPRfntaHTa/UA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83533 uniprotkb:O83958 intact:EBI-1600899|ensemblbacteria:AAC65508|ensemblbacteria:AGN75709 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83533_trepa(display_long)|uniprotkb:TP_0521(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600910|imex:IM-9152-1783 author score:0.003724617 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:WP_010881969.1|ensemblbacteria:AAC65508(transcript)|ensemblbacteria:AGN75709(transcript)|ensemblbacteria:TP_0521(gene)|ensemblbacteria:TPANIC_0521(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0521; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+PNQP6QJzEp9m1aFpHYEcYrHSjc243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:33AB343EF1A70633|rigid:tCzsRjbFvhFDBz6Zm1onr3/EcVc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83533 uniprotkb:O83982 intact:EBI-1600899|ensemblbacteria:AAC65508|ensemblbacteria:AGN75709 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83533_trepa(display_long)|uniprotkb:TP_0521(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600895|imex:IM-9152-1781 author score:0.414759643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:WP_010881969.1|ensemblbacteria:AAC65508(transcript)|ensemblbacteria:AGN75709(transcript)|ensemblbacteria:TP_0521(gene)|ensemblbacteria:TPANIC_0521(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0521; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:+PNQP6QJzEp9m1aFpHYEcYrHSjc243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:4B996ACC02AB6FD6|rigid:dTLEHsKlmh6C53fGrTVE3HHvx80 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O84000 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1584675|ensemblbacteria:AAC26591 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y1037_trepa(display_long)|uniprotkb:TP_1037(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600916|imex:IM-9152-1784 author score:0.406113471 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR004254(Hly-III related)|interpro:IPR005744(HylII)|ensemblbacteria:AAC26591(transcript)|ensemblbacteria:TP_1037(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1037; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:r+uWDoYer8CosA2mHSlK0VJXjfM243276 intact-crc:91CAB5473AC31EEC|rigid:nldrpuIXPU8wqHSKF2Cjub8ds/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O84000 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1584675|ensemblbacteria:AAC26591 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y1037_trepa(display_long)|uniprotkb:TP_1037(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600922|imex:IM-9152-1785 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004254(Hly-III related)|interpro:IPR005744(HylII)|ensemblbacteria:AAC26591(transcript)|ensemblbacteria:TP_1037(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1037; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:r+uWDoYer8CosA2mHSlK0VJXjfM243276 intact-crc:B5A2F0B590554C26|rigid:42HdFtfgUSYM5ABrjeeUFxQkttw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O84000 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1584675|ensemblbacteria:AAC26591 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y1037_trepa(display_long)|uniprotkb:TP_1037(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600928|imex:IM-9152-1786 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004254(Hly-III related)|interpro:IPR005744(HylII)|ensemblbacteria:AAC26591(transcript)|ensemblbacteria:TP_1037(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1037; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:r+uWDoYer8CosA2mHSlK0VJXjfM243276 intact-crc:43C928BE70871D0B|rigid:CVYdqN/3idBXjtrYt1DTwUktRkA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83463 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600940|imex:IM-9152-1788 author score:0.399873643 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:8C5815876DF1895F|rigid:nkNH5NLPCtlv3c7GRUBPchvSMbc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O84000 uniprotkb:O83745 intact:EBI-1584675|ensemblbacteria:AAC26591 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y1037_trepa(display_long)|uniprotkb:TP_1037(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600934|imex:IM-9152-1787 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004254(Hly-III related)|interpro:IPR005744(HylII)|ensemblbacteria:AAC26591(transcript)|ensemblbacteria:TP_1037(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1037; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:r+uWDoYer8CosA2mHSlK0VJXjfM243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:79F2FAC7AADC7BE6|rigid:1xfcjwWnG2axp6zRxxCwmPuymjk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83781 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600946|imex:IM-9152-1789 author score:0.319518858 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 intact-crc:38BB986CB05D44F9|rigid:VPFvn7D5rT4TES+Q9wanVMlPUAI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83982 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600952|imex:IM-9152-1790 author score:0.313693853 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:66C915F6FF606EDF|rigid:38t2TIyQZXFP3cnHaGCjVIiCQ/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:P21992 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600958|imex:IM-9152-1791 author score:0.310076695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:E1B205F168A406FE|rigid:ocLbWL4z5JMlr+14+klVrMMBPIE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83574 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600964|imex:IM-9152-1792 author score:0.177010321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:CCCFBDE2EEEE9352|rigid:u8xhYScaKQUquX3yL6Or8lC15LI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83781 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600970|imex:IM-9152-1793 author score:0.119790274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 intact-crc:DBCAC85DBDCD0510|rigid:Of5DILRXBy4stZhjvhWtnEsNINM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83781 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600982|imex:IM-9152-1795 author score:0.069998513 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 intact-crc:3B88E923DDBA2D2A|rigid:eqsYrg2amZ2j7HpX4IWCMRKgYEA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83667 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600976|imex:IM-9152-1794 author score:0.101298891 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:172431E04D0BE659|rigid:hy4IRn5XgygaszLdQiOxFHZV4Xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83958 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600994|imex:IM-9152-1797 author score:0.001222235 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:78AFB8B3893AC4FA|rigid:o+BfibiyF0tcOvT1JBU4Iy4q+XM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83781 uniprotkb:O83954 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1600988|imex:IM-9152-1796 author score:0.020253008 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0803; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:FF3BC6B42370B6AE|rigid:QoeeHZsl5PwMrbje+DR/8Uc/Jq0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83675 uniprotkb:O83531 intact:EBI-1601000|ensemblbacteria:AAC26567 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:dpo3a_trepa(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:TP_0669(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601005|imex:IM-9152-1798 author score:0.397406982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|refseq:WP_010882114.1|ensemblbacteria:AAC26567(transcript)|ensemblbacteria:TP_0669(gene)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0669; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0+1yzoLXqMEGPzOBcDN9MRnrYg243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:541B40AA0736B2B0|rigid:hxkCZ112yMGGfOyluIvB9aBVpaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83675 uniprotkb:O83413 intact:EBI-1601000|ensemblbacteria:AAC26567 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:dpo3a_trepa(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:TP_0669(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601011|imex:IM-9152-1799 author score:0.167860044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR004805(DNA polymerase III, alpha subunit)|refseq:WP_010882114.1|ensemblbacteria:AAC26567(transcript)|ensemblbacteria:TP_0669(gene)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0669; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0+1yzoLXqMEGPzOBcDN9MRnrYg243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:60A30547C0BAD7BD|rigid:E5cVZg/uAiIJEmzYBlPsGpyk9d8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83668 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1601021|ensemblbacteria:AAC65635 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:alf_trepa(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:Fructose-1,6-bisphosphate aldolase(gene name synonym)|uniprotkb:fda(gene name synonym)|uniprotkb:TP_0662(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601017|imex:IM-9152-1800 author score:0.392870254 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011289(Fructose-1,6-bisphosphate aldolase, class II)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|refseq:WP_010882107.1|ensemblbacteria:AAC65635(transcript)|ensemblbacteria:TP_0662(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0662; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:2ZlmTynCZu1UtIbTCAyblxoxVFQ243276 intact-crc:DBABF2D19E6A4F23|rigid:6saj0wbJUSOcNxf2mxlVDpCqdjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83668 uniprotkb:O83413 intact:EBI-1601021|ensemblbacteria:AAC65635 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:alf_trepa(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:Fructose-1,6-bisphosphate aldolase(gene name synonym)|uniprotkb:fda(gene name synonym)|uniprotkb:TP_0662(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601027|imex:IM-9152-1801 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011289(Fructose-1,6-bisphosphate aldolase, class II)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|refseq:WP_010882107.1|ensemblbacteria:AAC65635(transcript)|ensemblbacteria:TP_0662(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0662; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2ZlmTynCZu1UtIbTCAyblxoxVFQ243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:D10B9182C72E5DCE|rigid:dp+BYQndZylkG0JafaPSW3oFjL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83668 uniprotkb:O83954 intact:EBI-1601021|ensemblbacteria:AAC65635 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:alf_trepa(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:Fructose-1,6-bisphosphate aldolase(gene name synonym)|uniprotkb:fda(gene name synonym)|uniprotkb:TP_0662(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601033|imex:IM-9152-1802 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011289(Fructose-1,6-bisphosphate aldolase, class II)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|refseq:WP_010882107.1|ensemblbacteria:AAC65635(transcript)|ensemblbacteria:TP_0662(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0662; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2ZlmTynCZu1UtIbTCAyblxoxVFQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:EFA81BD687FFCB31|rigid:fB9SMOsuJl6VEZhr1+qsW+G7ZTM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83668 uniprotkb:O83958 intact:EBI-1601021|ensemblbacteria:AAC65635 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:alf_trepa(display_long)|uniprotkb:fba(gene name)|psi-mi:fba(display_short)|uniprotkb:Fructose-1,6-bisphosphate aldolase(gene name synonym)|uniprotkb:fda(gene name synonym)|uniprotkb:TP_0662(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601039|imex:IM-9152-1803 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR011289(Fructose-1,6-bisphosphate aldolase, class II)|interpro:IPR000771(Ketose-bisphosphate aldolase, class-II)|refseq:WP_010882107.1|ensemblbacteria:AAC65635(transcript)|ensemblbacteria:TP_0662(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0662; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2ZlmTynCZu1UtIbTCAyblxoxVFQ243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1FAE443BDB2FE19D|rigid:HYzmrWhekrwOB1ohShAzAy5Wkdc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96120 uniprotkb:O83124 intact:EBI-1592013|uniprotkb:Q7DFP9 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:p96120_trepl(display_long)|uniprotkb:troR(gene name)|psi-mi:troR(display_short)|uniprotkb:FA889_00910(orf name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601045|imex:IM-9152-1804 author score:0.392153026 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001367(Iron dependent repressor)|interpro:IPR022689|interpro:IPR022687|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036390|interpro:IPR036421|interpro:IPR036388|refseq:WP_010881614.1 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0167|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aMu9a64zyTkT95QLR2fimy2I27o160 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:E73ABCEE84F21D53|rigid:6pxK4bF9SaSzLiTUJy+eciXMOLs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83124 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601051|imex:IM-9152-1805 author score:0.380479882 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:110AD85DFF9D2834|rigid:jeRr9HMSKN7qyR8dQ5u41mNge4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83865 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1589795|ensemblbacteria:AAC65865|ensemblbacteria:AGN76064 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83865_trepa(display_long)|uniprotkb:TP_0895(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601057|imex:IM-9152-1806 author score:0.379395224 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR005180(Protein of unknown function DUF302)|ensemblbacteria:AAC65865(transcript)|ensemblbacteria:AGN76064(transcript)|ensemblbacteria:TPANIC_0895(gene)|ensemblbacteria:TP_0895(gene)|refseq:WP_010882338.1|interpro:IPR035923 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0895|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:ZX7XoS5vDkIBmHSa7iHEo8sNgK4243276 intact-crc:B484D473C321AD37|rigid:swp0rhqlQ69J6OPE2NBurbc4YkM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83427 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601063|imex:IM-9152-1807 author score:0.373077102 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0412|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:B31B54677022912F|rigid:m/wZadeXQaRE6zOqpycZy5LAldM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27771 uniprotkb:O83124 intact:EBI-1593360|uniprotkb:O83775|ensemblbacteria:AAC65760 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:p5cr_trepa(display_long)|uniprotkb:proC(gene name)|psi-mi:proC(display_short)|uniprotkb:PCA reductase(gene name synonym)|uniprotkb:TP_0797(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601075|imex:IM-9152-1809 author score:0.36680201 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR028939|ensemblbacteria:AAC65760(transcript)|ensemblbacteria:TP_0797(gene)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0055129"(L-proline biosynthetic process)|refseq:WP_010882242.1|interpro:IPR029036|interpro:IPR036291 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0797|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nzwapTm7KjLpf0btHIa+PzwyOK4243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:A295D09357A4200F|rigid:Jaqh971OwzMjZXSuJDy1Ta+4okk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83526 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1592146|ensemblbacteria:AAC65501|ensemblbacteria:AGN75702 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83526_trepa(display_long)|uniprotkb:TP_0513(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601069|imex:IM-9152-1808 author score:0.373077102 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|ensemblbacteria:AAC65501(transcript)|ensemblbacteria:AGN75702(transcript)|ensemblbacteria:TP_0513(gene)|ensemblbacteria:TPANIC_0513(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|refseq:WP_010881962.1|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0513|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:a4ai6430LAmmKePJdR/ZjwQF/H0243276 intact-crc:39B1618785226584|rigid:mr/PNs3nVB2a3fHSDeKdqCPr7Cg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83962 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1592165|ensemblbacteria:AAC26585 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601081|imex:IM-9152-1810 author score:0.348252742 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 intact-crc:71FCF5B01BC89376|rigid:bm8L3zYJGuHlR96BepuKGEUnLpI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O83124 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601087|imex:IM-9152-1811 author score:0.32422592 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:3B1EB80543B4DF13|rigid:hk2flCrTykkUVrDPrbYDXECe0Jw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83124 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601093|imex:IM-9152-1812 author score:0.318355248 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:0A93E323CEF43F4F|rigid:3qigPAJeobPL8rncYuOC9oyEZg0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83124 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601099|imex:IM-9152-1813 author score:0.312541712 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:561CEB88F8F2CF6D|rigid:vLCfD6Za2rcuxpytbBWX3ZU42kI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83939 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601111|imex:IM-9152-1815 author score:0.262974485 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:8C2712B1B21BE882|rigid:T7vHAfHVECNa6Somw4KMWpiGLYU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83068 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601105|imex:IM-9152-1814 author score:0.301090965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:C3CB8BAF11E519EC|rigid:1wc4LuASgE52B+ll88kc8Nzrfqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83124 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601117|imex:IM-9152-1816 author score:0.247622473 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:C9AD26FD5865EA33|rigid:jaybKLyJWy/UwynNZNNkn3kCmYI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83124 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601129|imex:IM-9152-1818 author score:0.22810846 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:51EF77617C341261|rigid:oXuDqUVhUslseLQLShpXj4MtZJc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83459 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601123|imex:IM-9152-1817 author score:0.22810846 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 intact-crc:D0C0565C945CC9BC|rigid:kGQxltZUy2MGQ2TMzRCAJNM+rC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83124 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601135|imex:IM-9152-1819 author score:0.22810846 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:263C1DFB376C68DA|rigid:a3a5GicjrowCUHLxaXAqLbCg0N4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83805 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601141|imex:IM-9152-1820 author score:0.209703637 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:5EDE528F3F56B2CB|rigid:Pe9GGFxgZbgScijLeO4CCrGStgU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83124 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601147|imex:IM-9152-1821 author score:0.161138354 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:95A1F7438625DBC1|rigid:suwxVt8ncQSV8LkihXD836lSiio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83463 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601153|imex:IM-9152-1822 author score:0.14376131 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:44E6895EA7AD60B2|rigid:At/7hLZvf3M6sT3NMreFItXvTVE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83982 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601165|imex:IM-9152-1824 author score:0.103279113 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:E692B04F18EE0944|rigid:Ucm3X84FrZWkDWJVEl4lCcVMeQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83124 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601159|imex:IM-9152-1823 author score:0.103279113 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:0915F434BB58B105|rigid:96OKbTAjkxeSYHTBW6Vp5VC849U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83969 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601171|imex:IM-9152-1825 author score:0.082897695 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:8CDC63406D566AA0|rigid:lxahsHlG10sEnnrdCBnqe/vm5oc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83312 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601177|imex:IM-9152-1826 author score:0.076960537 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:15178A1F9A62AD00|rigid:E9yPWG9681vb8blg/o12rhcwSH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83574 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601195|imex:IM-9152-1829 author score:0.051410251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:DFBF7324DCD9D525|rigid:UnlDV2Z4RUwJL3Oc+Am9LgXnySA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:P21992 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601189|imex:IM-9152-1828 author score:0.073221591 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:C8788215E75A8EC4|rigid:r1cJUCGcgRkmEG50GCAd9mOJmn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83099 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601183|imex:IM-9152-1827 author score:0.075069678 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:06C5DB524D642809|rigid:mYVO+KHeSOgSS48X9iEBCV2GHpo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83124 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601201|imex:IM-9152-1830 author score:0.033155761 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:EA7325A8D2CE3831|rigid:T5VAzDSpflxafyDmptjjW865Pns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83124 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601207|imex:IM-9152-1831 author score:0.029871873 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:3EBCD88FEE642ADD|rigid:qnkgwnyW5xvO8w9bfDzV5m5MmOs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83124 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601213|imex:IM-9152-1832 author score:0.027618074 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:8B00C63F73C1B409|rigid:d7ixWdf0k7UQ/CGIDNPq1lbvJvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83124 uniprotkb:O83282 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601219|imex:IM-9152-1833 author score:0.006249797 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:23168B7B59F77DA2|rigid:zos475UxxOMGs1XyqxKZlemJt6M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83124 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601225|imex:IM-9152-1834 author score:0.005181868 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:34D0F6B432073A56|rigid:6MnoS1sh5bBZ15x1mzdpT7Siaw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83124 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582125|ensemblbacteria:AAC65081|ensemblbacteria:AGN75305 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83124_trepa(display_long)|uniprotkb:TP_0086(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601231|imex:IM-9152-1835 author score:0.000308261 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR009875(Type IV pilus assembly PilZ)|ensemblbacteria:AAC65081(transcript)|ensemblbacteria:AGN75305(transcript)|ensemblbacteria:TPANIC_0086(gene)|go:"GO:0035438"(cyclic-di-GMP binding)|ensemblbacteria:TP_0086(gene)|refseq:WP_010881535.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0086; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:NuGHTxZoyVb0RkofSsVwc0xxvBM243276 intact-crc:B53FC42B23E57A9C|rigid:400Pl706bcvKPnerkS9Tn5/as8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83178 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601240|imex:IM-9152-1836 author score:0.388836562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 intact-crc:B78882ADAFC92507|rigid:+5KxaBDPIBbb2I7VcOnR9F91bC8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83305 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601252|imex:IM-9152-1838 author score:0.347357628 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:7506A49C376CD467|rigid:hx0ZjXMdWdn0PLPSELV5EwUVbO0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83531 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601246|imex:IM-9152-1837 author score:0.388622782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:9BB2A0872CAF1678|rigid:Sg2X7R02Jx0jFHeICqqHqGcWWYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83877 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601264|imex:IM-9152-1840 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:B8230572D2E52B29|rigid:/bHDF6nfRrkY1O6x1uT22Flpzx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83982 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601258|imex:IM-9152-1839 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:4FA4979A93683759|rigid:Gprey9sxJL5o+2moubH1A5NyNRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83178 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601270|imex:IM-9152-1841 author score:0.065997631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 intact-crc:8E36E601E4A80961|rigid:WlMMxt2AKAYNtBkuXT9WyQH+OG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83954 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601276|imex:IM-9152-1842 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:6B96B34F75F15DED|rigid:hJ9YhI1rzZY3HyrJaI1+SqN5Uzg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83178 uniprotkb:O83958 intact:EBI-1601237|ensemblbacteria:AAC65130|ensemblbacteria:AGN75362 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83178_trepa(display_long)|uniprotkb:TP_0142(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601282|imex:IM-9152-1843 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010881590.1|ensemblbacteria:AAC65130(transcript)|ensemblbacteria:AGN75362(transcript)|ensemblbacteria:TP_0142(gene)|ensemblbacteria:TPANIC_0142(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR015853(ABC transporter, ferric cation import, FbpC) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0142; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:laArdpv8AyoQYhbttXhDQTjcjTA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:0DFFD96C4313185F|rigid:IWJVhv8oRJu4V7E23dj3Zo2MFa8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83463 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601288|imex:IM-9152-1844 author score:0.384936692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:E96051C0AD9BC799|rigid:o0lB17ji4StnvpyIrHo7qvb9Y/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83543 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601303|imex:IM-9152-1846 author score:0.272857387 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 intact-crc:70ABED4487FA4277|rigid:UPAa13w1GvksjqSNXtnhjuNrkSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83543 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601297|imex:IM-9152-1845 author score:0.300364872 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 intact-crc:C0D793B2F503CCDD|rigid:1meGQW1CaVFTmAYpyVBE25f1jTA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83927 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601309|imex:IM-9152-1847 author score:0.204713982 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:0CCC68D5D3B495B4|rigid:k8LtCHjAfIJHKz4fM3K4YtI9AQs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83574 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601315|imex:IM-9152-1848 author score:0.168066845 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:823BF29F1C07A82C|rigid:6nb22Vmd6c4BNxFzYdp4Lj4j4I8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83543 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601321|imex:IM-9152-1849 author score:0.113339703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 intact-crc:CFC8B07C920C2CDE|rigid:atRbGyay+AtdnTewFQlIObovx5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83413 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601327|imex:IM-9152-1850 author score:0.102959777 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:41923A7EB910469D|rigid:gucvXa84aszLmdfN1CoAELYgPBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83543 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601345|imex:IM-9152-1853 author score:0.022905901 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 intact-crc:3351AE815C0E4549|rigid:QXCnifD5ZN4Vv2RmT3XPq3gzJ88 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83543 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601339|imex:IM-9152-1852 author score:0.055314123 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 intact-crc:CB7F32BAF77CFAEE|rigid:i4Bb3N2KNp1r6PiKHmFdvSJ0gjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83667 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601333|imex:IM-9152-1851 author score:0.095735759 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:214BB37EA4E4BBCD|rigid:4z4faOgYdI3pTlqxTaVMwosmdt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83543 uniprotkb:O83954 intact:EBI-1601292|ensemblbacteria:AAC65518|ensemblbacteria:AGN75719 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83543_trepa(display_long)|uniprotkb:TP_0531(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601351|imex:IM-9152-1854 author score:0.019046425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|ensemblbacteria:AAC65518(transcript)|ensemblbacteria:AGN75719(transcript)|ensemblbacteria:TP_0531(gene)|ensemblbacteria:TPANIC_0531(gene)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR036906 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0531; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CG8K9GKKvAM/SlP2kNrqpa+XzXQ243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F6EA984C2CACB93C|rigid:hxo94GiNIkb/lFa9O1SY5pEEsIs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83974 uniprotkb:O83398 intact:EBI-1601361|ensemblbacteria:AAC65961 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:ndk_trepa(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:TP_1010(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601357|imex:IM-9152-1855 author score:0.384703151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|refseq:WP_010882454.1|ensemblbacteria:AAC65961(transcript)|ensemblbacteria:TP_1010(gene)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036850 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1010; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7c60rcBp9LWCW8H6X6H4vaS+pgw243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:05C33FF3EC108588|rigid:efYPND+cON9igsgapjmP+MCrs2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83974 uniprotkb:O83099 intact:EBI-1601361|ensemblbacteria:AAC65961 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:ndk_trepa(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:TP_1010(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601367|imex:IM-9152-1856 author score:0.305843263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|refseq:WP_010882454.1|ensemblbacteria:AAC65961(transcript)|ensemblbacteria:TP_1010(gene)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036850 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1010; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7c60rcBp9LWCW8H6X6H4vaS+pgw243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:C9FC3AFD01FF7ACC|rigid:+8qrlUDXSB/0qLNZq5UnKMzF2n0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83974 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1601361|ensemblbacteria:AAC65961 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:ndk_trepa(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:TP_1010(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601373|imex:IM-9152-1857 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|refseq:WP_010882454.1|ensemblbacteria:AAC65961(transcript)|ensemblbacteria:TP_1010(gene)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036850 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1010; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:7c60rcBp9LWCW8H6X6H4vaS+pgw243276 intact-crc:3691BA86179AC886|rigid:r7P2wY3ubSnFCK03AxHFqXFBKmo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83974 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1601361|ensemblbacteria:AAC65961 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:ndk_trepa(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:TP_1010(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601385|imex:IM-9152-1859 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|refseq:WP_010882454.1|ensemblbacteria:AAC65961(transcript)|ensemblbacteria:TP_1010(gene)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036850 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1010; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:7c60rcBp9LWCW8H6X6H4vaS+pgw243276 intact-crc:BED057F348954839|rigid:0osJ7QeOgSbkVP01ObFg5sFmdbg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83974 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1601361|ensemblbacteria:AAC65961 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:ndk_trepa(display_long)|uniprotkb:ndk(gene name)|psi-mi:ndk(display_short)|uniprotkb:Nucleoside-2-P kinase(gene name synonym)|uniprotkb:TP_1010(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601379|imex:IM-9152-1858 author score:0.093346775 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|refseq:WP_010882454.1|ensemblbacteria:AAC65961(transcript)|ensemblbacteria:TP_1010(gene)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR036850 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1010; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:7c60rcBp9LWCW8H6X6H4vaS+pgw243276 intact-crc:D468FA272F8437D9|rigid:D/4XO+3gHApod94lK8NIVqVDAps false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83962 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1592165|ensemblbacteria:AAC26585 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601397|imex:IM-9152-1861 author score:0.377207262 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 intact-crc:201816FBA8A8F9E5|rigid:+nWE5s7LcFfCmrDBMWuc8w8Paeg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83158 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601391|imex:IM-9152-1860 author score:0.383552535 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 intact-crc:1023D93793AD988D|rigid:LWU7TZouKJBJmtRDF3L8UrYZYR0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83361 uniprotkb:O83427 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601403|imex:IM-9152-1862 author score:0.352262501 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:5566637616DB5B4F|rigid:pMIJRTuZIbE1dcD5hkbqysY/iy4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83913 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601409|imex:IM-9152-1863 author score:0.334060589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:85B6416D9366AF44|rigid:vab6uWTC+iDfOfsW+XwME3eH7kI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83595 uniprotkb:O83427 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601415|imex:IM-9152-1864 author score:0.328098301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:9DB4C17E1B1DFA7D|rigid:ShOF1eY3QE2B8mlVVBcRkXfoDIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83106 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601421|imex:IM-9152-1865 author score:0.31054637 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:F1DFE27B56C6ED88|rigid:lxBTE+5susx1yR3qVQ3qmkk29ls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83275 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601427|imex:IM-9152-1866 author score:0.304811667 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:E7198B2B6616AA76|rigid:coqQB3F2vUclJ5gXW0a/B1xTj5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83239 uniprotkb:O83427 intact:EBI-1198384|intact:EBI-1582038|ensemblbacteria:AAC65209 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:rl36_trepa(display_long)|uniprotkb:rpmJ(gene name)|psi-mi:rpmJ(display_short)|uniprotkb:TP_0209(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601433|imex:IM-9152-1867 author score:0.266403705 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000473(Ribosomal protein L36)|refseq:WP_010881657.1|ensemblbacteria:AAC65209(transcript)|ensemblbacteria:TP_0209(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR035977 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0209|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JPEJDL6m30JkfcSmcIvcCdkK0sw243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:D5325DF44A182B34|rigid:pR9gUIggoWZvIz+4R02y9jTrPP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83752 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601445|imex:IM-9152-2214 author score:0.250919657 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:92D88B3925EC3DB0|rigid:I2Rl89tEbI5bQduoXgMPWR9AIQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83311 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601439|imex:IM-9152-2213 author score:0.266403705 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:151FB6ADD2FFA7B3|rigid:CwK4eL2To6nbwdvM4x2D1TYucWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83427 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601457|imex:IM-9152-2216 author score:0.231225662 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:1A1EF0D861A0526D|rigid:w7JOTtlmSto/4wRRbextCAuqtQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83565 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601451|imex:IM-9152-2215 author score:0.236046 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:AE6C23AE5D1759BA|rigid:RQ4JeE0D1Kt2YfRBjuLXWmPpfBw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83738 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601465|imex:IM-9152-2217 author score:0.221792954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:831A9EA9B560423A|rigid:ExHCSKKYIi/17yFck+ZsO2+bcrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83427 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601471|imex:IM-9152-2218 author score:0.186847162 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:31130AE822021CDD|rigid:tI5icZ2F31dJhjqQf3lsepi7Ru0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83427 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601477|imex:IM-9152-2219 author score:0.178803782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:E379A5B7E41DA9CE|rigid:TgPy9oioKJsY0PxEf7eFCx1WNt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83398 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601489|imex:IM-9152-2221 author score:0.115474654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:8FA87B2D00C0BC51|rigid:mcub3MphyptGD2vY5eU9tAfTcSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83427 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601483|imex:IM-9152-2220 author score:0.118253118 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:DFC513E1DF2F3F13|rigid:dnZ8bTiRxnwmfzritIAHcY+KrMc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83427 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601495|imex:IM-9152-2222 author score:0.102420713 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:AA99A9D90A80C190|rigid:oRhNJq2ZzKTyqSEmc6x2jTVfvy8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83427 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601501|imex:IM-9152-2223 author score:0.09293596 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:626A3761D69F150B|rigid:BMCD7O8ixOr2KGsftIQ2bjNomxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83427 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601507|imex:IM-9152-2224 author score:0.086347549 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:6CCCEE5D9EB152E9|rigid:ABhV63Nr2NpOfj3jPc4PjuEnzNw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83427 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601513|imex:IM-9152-2225 author score:0.084247109 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:B92EC6F3C7CA5FBE|rigid:gc65F5bFzz7w+U07ZdPE3gjbujY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:P21992 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601519|imex:IM-9152-2226 author score:0.082193167 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:F59D8101DBE05B38|rigid:0Vb9Pn+tw7faCIsv5lCJcOavIxM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83427 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601525|imex:IM-9152-2227 author score:0.072592789 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:786107AB88341C16|rigid:b51XolqT8+OPm/DvxFVjA6Ptsq8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83667 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601543|imex:IM-9152-2230 author score:0.031190064 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B38F4279D1BDFD27|rigid:6i/429931NaFWy0NzD1DEMCv4h0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83877 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601531|imex:IM-9152-2228 author score:0.03741641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:AD3874BBCE362643|rigid:lkodUdM4cfetd02AtR+Uje+iX/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83427 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601537|imex:IM-9152-2229 author score:0.033725249 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:BB32E36CF0593EDF|rigid:3uEeXo+6RIYvgracu5Sd49HU/rM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83282 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601555|imex:IM-9152-2232 author score:0.007078233 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:A1868EB1ACE457A1|rigid:0Np3yn0PtvWos2m1TQgdiBNrGuY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83767 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601549|imex:IM-9152-2231 author score:0.021045343 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:333D0C307786961E|rigid:35nZ2qqsbm9/SL3IVWE9784LxBQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83427 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601561|imex:IM-9152-2233 author score:0.005869583 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:321F961F160DD233|rigid:8rZgYImV/F6eSIiEJgfBTs98gdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83427 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601567|imex:IM-9152-2234 author score:0.0003494 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0412; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:E2FF1D2DF777C431|rigid:c7rs8TI8Z1WSOWFTXgC83s2Ufro false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83769 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1601577|ensemblbacteria:AAC65756|ensemblbacteria:AGN75962 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83769_trepa(display_long)|uniprotkb:TP_0790(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601582|imex:IM-9152-2236 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004869(MMPL)|interpro:IPR000731(Sterol-sensing 5TM box)|refseq:WP_010882235.1|ensemblbacteria:AAC65756(transcript)|ensemblbacteria:AGN75962(transcript)|ensemblbacteria:TP_0790(gene)|ensemblbacteria:TPANIC_0790(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0790; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:PSxQ5hEMNkjtbw5GG9I79REYYuA243276 intact-crc:3B136EC521BD08D1|rigid:IALFenfBcCC4wMzqDKNk+xSwYjQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83769 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1601577|ensemblbacteria:AAC65756|ensemblbacteria:AGN75962 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:o83769_trepa(display_long)|uniprotkb:TP_0790(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601573|imex:IM-9152-2235 author score:0.382503445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR004869(MMPL)|interpro:IPR000731(Sterol-sensing 5TM box)|refseq:WP_010882235.1|ensemblbacteria:AAC65756(transcript)|ensemblbacteria:AGN75962(transcript)|ensemblbacteria:TP_0790(gene)|ensemblbacteria:TPANIC_0790(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0790; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:PSxQ5hEMNkjtbw5GG9I79REYYuA243276 intact-crc:B047BB4192E57466|rigid:7ExJMZ9p4Umx8oCq9OBY7AUyobU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83769 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1601577|ensemblbacteria:AAC65756|ensemblbacteria:AGN75962 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83769_trepa(display_long)|uniprotkb:TP_0790(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601588|imex:IM-9152-2237 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004869(MMPL)|interpro:IPR000731(Sterol-sensing 5TM box)|refseq:WP_010882235.1|ensemblbacteria:AAC65756(transcript)|ensemblbacteria:AGN75962(transcript)|ensemblbacteria:TP_0790(gene)|ensemblbacteria:TPANIC_0790(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0790; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:PSxQ5hEMNkjtbw5GG9I79REYYuA243276 intact-crc:3560BFBC1123E8CA|rigid:VgjjWwQ6fiMJUGlxyTfU1gN2YKs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83574 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601600|imex:IM-9152-2239 author score:0.250086168 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1023; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:CA2873F74D541BC3|rigid:187ocR0A1nseKlZquFcgm5BiRxU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83954 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601606|imex:IM-9152-2240 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1023; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:CCE5BD31E6D38145|rigid:NwOadMOJ8RtwPrTCW3v7TZ/r3DA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83986 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601594|imex:IM-9152-2238 author score:0.382503445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1023; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:437D133499393021|rigid:aD75ARj3Mj4aUi7/kliYouQ7VG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83385 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1601612|ensemblbacteria:AAC65361 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601615|imex:IM-9152-2241 author score:0.376280693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 intact-crc:E82638EEA28535E7|rigid:gObYeYOoZMiLLtQeGQT1rX+KBe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83385 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1601612|ensemblbacteria:AAC65361 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601621|imex:IM-9152-2242 author score:0.287163122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 intact-crc:84D9A67DA8FDDF29|rigid:zL0ecLVnXfFXZ7WlazMrTKkcV1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83385 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1601612|ensemblbacteria:AAC65361 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601627|imex:IM-9152-2243 author score:0.14883104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 intact-crc:F10F08FA5E4CA02A|rigid:2E3KsFA2U0tHk6YHqZ1C8Z7zpw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83385 uniprotkb:O83767 intact:EBI-1601612|ensemblbacteria:AAC65361 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601633|imex:IM-9152-2244 author score:0.088177508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:AA432E2298BCFD0E|rigid:EeA9nqSZ9Ig3Q5p7CM59urlCcBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83385 uniprotkb:O83282 intact:EBI-1601612|ensemblbacteria:AAC65361 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601639|imex:IM-9152-2245 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:5D2CED12ABFBA625|rigid:UdI73hXF6yOvriV7UszVhvoAd/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83330 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1601651|ensemblbacteria:AAC65297|ensemblbacteria:AGN75512 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83330_trepa(display_long)|uniprotkb:TP_0308(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601654|imex:IM-9152-2247 author score:0.374951877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|refseq:WP_010881757.1|ensemblbacteria:AAC65297(transcript)|ensemblbacteria:AGN75512(transcript)|ensemblbacteria:TP_0308(gene)|ensemblbacteria:TPANIC_0308(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0308; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:fOZT08Z+D6wT3l6apIz4FK1j2rY243276 intact-crc:2A8356A38455100C|rigid:hvVeiXz07946StbdId7o0Lm6cmk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83385 uniprotkb:O83954 intact:EBI-1601612|ensemblbacteria:AAC65361 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y370_trepa(display_long)|uniprotkb:TP_0370(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601645|imex:IM-9152-2246 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65361(transcript)|ensemblbacteria:TP_0370(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0370; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xU5jsWXD3ycE8RnpOKYixXXzppo243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:DF8D8E12EF79F59E|rigid:TbP/Qbvl3JD3+Lr9Si/JX+cc5uw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83330 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1601651|ensemblbacteria:AAC65297|ensemblbacteria:AGN75512 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83330_trepa(display_long)|uniprotkb:TP_0308(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601660|imex:IM-9152-2248 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|refseq:WP_010881757.1|ensemblbacteria:AAC65297(transcript)|ensemblbacteria:AGN75512(transcript)|ensemblbacteria:TP_0308(gene)|ensemblbacteria:TPANIC_0308(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0308; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:fOZT08Z+D6wT3l6apIz4FK1j2rY243276 intact-crc:3F32E4FBB42C659B|rigid:Mz4SLdiuGhQBDUHfUXSrRJXSdCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83330 uniprotkb:O83958 intact:EBI-1601651|ensemblbacteria:AAC65297|ensemblbacteria:AGN75512 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83330_trepa(display_long)|uniprotkb:TP_0308(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601666|imex:IM-9152-2249 author score:0.002666406 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001638(Bacterial extracellular solute-binding protein, family 3)|refseq:WP_010881757.1|ensemblbacteria:AAC65297(transcript)|ensemblbacteria:AGN75512(transcript)|ensemblbacteria:TP_0308(gene)|ensemblbacteria:TPANIC_0308(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0308; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fOZT08Z+D6wT3l6apIz4FK1j2rY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D8667533B07F87FA|rigid:13sQmAeEfDpFv76dWdfciDNcLSw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83246 uniprotkb:O83969 intact:EBI-1601672|ensemblbacteria:AAC65204 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:dnak_trepa(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:TP_0216(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601676|imex:IM-9152-2250 author score:0.371924141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012725(Chaperone DnaK)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129|refseq:WP_010881664.1|ensemblbacteria:AAC65204(transcript)|ensemblbacteria:TP_0216(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR029047|interpro:IPR029048 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0216; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aetYW3eGKdZNTsejtE/7HDkZtA8243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:697E942EE30D3B4D|rigid:k6pFkpx+AO2SWhHla2zOk24Wnsc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83246 uniprotkb:O83958 intact:EBI-1601672|ensemblbacteria:AAC65204 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:dnak_trepa(display_long)|uniprotkb:dnaK(gene name)|psi-mi:dnaK(display_short)|uniprotkb:Heat shock protein 70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein(gene name synonym)|uniprotkb:HSP70(gene name synonym)|uniprotkb:TP_0216(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601682|imex:IM-9152-2251 author score:0.003068202 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012725(Chaperone DnaK)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129|refseq:WP_010881664.1|ensemblbacteria:AAC65204(transcript)|ensemblbacteria:TP_0216(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR029047|interpro:IPR029048 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0216; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aetYW3eGKdZNTsejtE/7HDkZtA8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:69E41DB2CA2D1661|rigid:mtIMpHdP/KqzMJslAZg4Cs21NaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83956 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1590930|ensemblbacteria:AAC65947 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:rubr_trepa(display_long)|uniprotkb:TP_0991(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601694|imex:IM-9152-2253 author score:0.183444879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR018527|ensemblbacteria:AAC65947(transcript)|ensemblbacteria:TP_0991(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|interpro:IPR024922|interpro:IPR024934|interpro:IPR024935|refseq:WP_010882435.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0991; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:zn6kAatILy/x8kIkBZ3z/pfLkLc243276 intact-crc:C6D2CE857A43CD98|rigid:Cj119NBMt/agD5GYn5hOzg3SwNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83956 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1590930|ensemblbacteria:AAC65947 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:rubr_trepa(display_long)|uniprotkb:TP_0991(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601688|imex:IM-9152-2252 author score:0.371924141 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR018527|ensemblbacteria:AAC65947(transcript)|ensemblbacteria:TP_0991(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|interpro:IPR024922|interpro:IPR024934|interpro:IPR024935|refseq:WP_010882435.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0991; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:zn6kAatILy/x8kIkBZ3z/pfLkLc243276 intact-crc:A2660DAB89541153|rigid:K+VrXdiLvMcTHvrzZlbkCqZqND8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83089 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601700|imex:IM-9152-2254 author score:0.369983517 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:3679580B8837016D|rigid:ZRWxDS86fpgI8Sy4fuEgohbTpR4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83531 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601706|imex:IM-9152-2255 author score:0.339191351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:34DCD30D29E24A0C|rigid:+CxKIwbeuGPaQ1I2nbS6PBxhnuc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83312 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601712|imex:IM-9152-2256 author score:0.298310264 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:7E06E0913E40833E|rigid:DD2c5ZYrxHWnS+c3bYbrxaZZMMs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83089 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601718|imex:IM-9152-2257 author score:0.287163122 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:4563C6598382970E|rigid:C7uCGQIbtzPY0c0pGitvK76oDdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83089 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601724|imex:IM-9152-2258 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 intact-crc:36A36E11BBDB7CD2|rigid:VDDrW1gR72z1XHsnZSDeCeZvjRw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83089 uniprotkb:O83282 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601730|imex:IM-9152-2259 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0050; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:4EA45379AC17260E|rigid:1rd9i7TuD/a8kAXI2uXbcLtVS+M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83531 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601736|imex:IM-9152-2260 author score:0.367817664 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0989; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:29E066A3E544075A|rigid:9fDroI7jRRikKhraSjcJJpEACJQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83954 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601748|imex:IM-9152-2262 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0989; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:22629DBD049A8A61|rigid:riS20E7tVEKr0gWuYD/07sPmqvI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83877 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601742|imex:IM-9152-2261 author score:0.165413283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0989; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C28EC6D6DBE02F64|rigid:I6GoX9RyoIDB24kSub+JpXbbmTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83101 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1601760|ensemblbacteria:AAC65057 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:ssb_trepa(display_long)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:TP_0062(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601764|imex:IM-9152-2264 author score:0.367702975 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|refseq:WP_010881511.1|ensemblbacteria:AAC65057(transcript)|ensemblbacteria:TP_0062(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0006260"(DNA replication) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0062; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:bXPplBq3xT6zfOARZQG2Sj98Ag4243276 intact-crc:B15871A1CA150851|rigid:XHDPa1w9HDx5g/xF1yDavvLXeEE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83745 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601754|imex:IM-9152-2263 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0989; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:121094469DF3B324|rigid:wGfttsA6zpGBtEmgBGGv19aUoaQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83379 uniprotkb:O83312 intact:EBI-1601774|ensemblbacteria:AAC65345|ensemblbacteria:AGN75557 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83379_trepa(display_long)|uniprotkb:TP_0360(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601770|imex:IM-9152-2265 author score:0.367702975 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65345(transcript)|ensemblbacteria:AGN75557(transcript)|ensemblbacteria:TP_0360(gene)|ensemblbacteria:TPANIC_0360(gene) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0360; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7O+oZR13egi3vm08m1zo7LfUVgs243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:DF4E11E441BD2D76|rigid:gYI03ioZaWGlIDDAxkZpYIucXUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83971 uniprotkb:O83099 intact:EBI-1601779|ensemblbacteria:AAC65955 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601783|imex:IM-9152-2266 author score:0.366564062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:E88AD6AF71379F0F|rigid:ZEBrKTmyC88SFcMwoAd6nhk/skc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83971 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1601779|ensemblbacteria:AAC65955 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601789|imex:IM-9152-2267 author score:0.216510799 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 intact-crc:7226D0B72A662BF6|rigid:hVJLkJXj50gjCTvSD97EEOPDE70 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83971 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1601779|ensemblbacteria:AAC65955 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601795|imex:IM-9152-2268 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 intact-crc:7C632987E309763F|rigid:Sbc4YQxjUMOyWLBP8QYsQPtlLPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83971 uniprotkb:O83958 intact:EBI-1601779|ensemblbacteria:AAC65955 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601813|imex:IM-9152-2271 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:24834D4C12ED5F5C|rigid:dlhpSZX7BTqmRURvAzJLMD8jEIo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83971 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1601779|ensemblbacteria:AAC65955 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601801|imex:IM-9152-2269 author score:0.088177508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 intact-crc:D025A7EF2D57B3A3|rigid:BK1L7SLVLwrqSMErxQk1ufa+nFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83971 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1601779|ensemblbacteria:AAC65955 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:thyx_trepa(display_long)|uniprotkb:thyX(gene name)|psi-mi:thyX(display_short)|uniprotkb:FAD-dependent thymidylate synthase(gene name synonym)|uniprotkb:Thymidylate synthase ThyX(gene name synonym)|uniprotkb:TP_1007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601807|imex:IM-9152-2270 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003669(Thymidylate synthase ThyX)|ensemblbacteria:AAC65955(transcript)|ensemblbacteria:TP_1007(gene)|go:"GO:0006231"(dTMP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050797"("thymidylate synthase (FAD) activity")|interpro:IPR036098 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1007; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:FBU6bDpXyVCbtCK+p7FwIX2WZPs243276 intact-crc:A054A04CB0BE761A|rigid:/2/88+riMKndx8ZnlkwLG9TjmMQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83925 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198939|intact:EBI-1593707|ensemblbacteria:AAC65923 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y959_trepa(display_long)|uniprotkb:TP_0959(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601819|imex:IM-9152-2272 author score:0.362719427 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR019301|refseq:WP_010882403.1|ensemblbacteria:AAC65923(transcript)|ensemblbacteria:TP_0959(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0959|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:8JCzUQdbcWlp45gaIl2cTxmLZT4243276 intact-crc:5B2B9A2E75F10645|rigid:D0Oey7z0L18RCZ8hLwMfOKnOts0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83378 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601828|imex:IM-9152-2273 author score:0.344264367 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0807|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:4242F6379F87EFCE|rigid:LlJjyo3ie3vKzJiRtir9snGtFvQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83378 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601834|imex:IM-9152-2274 author score:0.338212454 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0981|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:993A4B16E6F81FBB|rigid:4PAB1I3bYBzNcM8uqNzOJYvlWIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83457 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601840|imex:IM-9152-2275 author score:0.332213031 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 intact-crc:B2FD87D578166053|rigid:csHPmClXYokal9DNk5uFKvhBYoU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07885 uniprotkb:O83378 intact:EBI-1198204|uniprotkb:Q7DFN8|intact:EBI-1582957 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o07885_trepl(display_long)|uniprotkb:orf4(gene name)|psi-mi:orf4(display_short)|uniprotkb:FA889_03755(orf name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601846|imex:IM-9152-2276 author score:0.326267562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009384(Flagellar)|refseq:WP_010882171.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0726|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QEJdDSps2ym7hUq77EjAW95JvCc160 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:82070B449E4478A9|rigid:Y/5hiQ8OYIEjfJ4ASAwgHQVxuXk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83373 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601852|imex:IM-9152-2277 author score:0.320377449 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:6167D42E8F4659A8|rigid:KNIwqzxwjq3G03n4cWlGydpwjrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83962 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1592165|ensemblbacteria:AAC26585 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601858|imex:IM-9152-2278 author score:0.320377449 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 intact-crc:EA4C64A5ABAE7939|rigid:OOtJxnDrDxWtY5kpr0tlFVdBDi0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83986 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601864|imex:IM-9152-2279 author score:0.291801608 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:0D54A5A2D829937F|rigid:1Iw44c05KA2kAfB1HX8WVizq4fc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83378 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601870|imex:IM-9152-2280 author score:0.280800351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:23B8DEDEF6F44D8A|rigid:uOLdaapNFDiCyuOwbbi90QeDdKg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83378 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601876|imex:IM-9152-2281 author score:0.275395538 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:B525D5355A0751D6|rigid:FEhlDzb2baWXKqxSzNwjtZl43Ms false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83542 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601882|imex:IM-9152-2282 author score:0.259573787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:F0104400BF1EE652|rigid:XOfsXqt2IR3CnDpHw88Yp7jUrvw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83098 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601888|imex:IM-9152-2283 author score:0.24935974 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:BBDCDE302144A2F4|rigid:gFCc/cCugvMylY0++tNGdOkpGqU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83596 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601894|imex:IM-9152-2284 author score:0.239417648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:02006978242052FD|rigid:M0ESQQRTgnkXpgZlHou0wFHS+tI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83939 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601900|imex:IM-9152-2285 author score:0.239417648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:BA081445C5DEA8B4|rigid:OKhDGy601r+9VULOLO5y+Wknm2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83378 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601906|imex:IM-9152-2286 author score:0.229750627 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:CAB8880AAABD77BC|rigid:7iIYEsdNMZWHLWqvVnsw9IM11vM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83670 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601912|imex:IM-9152-2287 author score:0.189690555 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:DAD35F0D3DBC5295|rigid:PCHKKNiGSdlwLQIBXJV/EFOGz7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83805 uniprotkb:O83378 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601918|imex:IM-9152-2288 author score:0.189690555 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:B310EA293215ECA7|rigid:ZbQrYYoVhPZlvjm3OwGxhusdbN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83709 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601924|imex:IM-9152-2289 author score:0.144910252 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:851A7D0D070EABAD|rigid:gjgwIw+RqXCPRZ9BcJAb2wxCFec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83463 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601930|imex:IM-9152-2290 author score:0.129014086 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:D58BC018D6BB0692|rigid:qQ/eRgbY5TWhs5y/6pkQKVh9s7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83378 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601936|imex:IM-9152-2291 author score:0.094516349 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:AEC4CFCDBBD3810A|rigid:oC7VFfqK6hjfxPBrjfRXhO9e5bU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83398 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601942|imex:IM-9152-2292 author score:0.09223726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:5E91F36E30006DC5|rigid:8dYwLIDIWAcyLQCnPB0hjIuY1C4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83378 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601948|imex:IM-9152-2293 author score:0.09223726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:DEEBD1A293B62077|rigid:nOVbOlqiVhXNnZmbgZ4O9oCUPfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83378 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601954|imex:IM-9152-2294 author score:0.081567969 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:5150906ADBFDF887|rigid:vZRlTPYurblwlMV8bvgEyTuCMu4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83378 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601960|imex:IM-9152-2295 author score:0.068517476 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:25F8A8F4941745AD|rigid:Dc60uXvD4ZLDFHOmkatLC7vgnrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83378 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601966|imex:IM-9152-2296 author score:0.06681904 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:873FF9DE53068609|rigid:FRSFjNGWwI31ZLxU8k3J4VzzU5I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:P21992 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601972|imex:IM-9152-2297 author score:0.065159761 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:7A4E6AC0B4D5EBF6|rigid:Zi35l9kuF1o5tgbE1w1SiI18spY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83378 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601978|imex:IM-9152-2298 author score:0.045631648 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:B28122982BAD1006|rigid:OaU6CLcl7SimyKt9S4NODEOJvt0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83413 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601984|imex:IM-9152-2299 author score:0.026446725 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:6CD4993BABAE9030|rigid:pFDrjgwUh7pxyf0hq88x6fNgWLk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83667 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601990|imex:IM-9152-2300 author score:0.024444838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:5E50472F0311DEEC|rigid:kZW+zhMNE23P//NHEk1fyiDOrA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83378 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1601996|imex:IM-9152-2301 author score:0.016456768 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:1611270C820B6865|rigid:2vsNdrS/qEMo9bDuBDI3mNeVX18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83378 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602002|imex:IM-9152-2302 author score:0.013668722 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:74094CD1A3461BE1|rigid:52Dl/DhcohTx8LgX4vvrHmNqXMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83378 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602008|imex:IM-9152-2303 author score:0.005517782 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:C6300B4E266665E3|rigid:ZrPpurXzsT0yaRKwM27XEysEC3A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83954 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602014|imex:IM-9152-2304 author score:0.00457436 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:9D41FE1C75FB3E2D|rigid:BCyAiYVdWOpOoMVk6WigzGlajQg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83958 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602020|imex:IM-9152-2305 author score:0.000271965 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0359; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:3E7804D0FA5D27F9|rigid:DLKAn7VAxup+eD+B/6zGPnv12nc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83109 uniprotkb:O83969 intact:EBI-1602026|ensemblbacteria:AAC65067 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y070_trepa(display_long)|uniprotkb:TP_0070(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602029|imex:IM-9152-2306 author score:0.357409441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881519.1|ensemblbacteria:AAC65067(transcript)|ensemblbacteria:TP_0070(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0070; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:91G4IIKloeuW7UsLhmi6pcif0zk243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:02F8358924EBAE6A|rigid:7koA49/ZEKwzm1dnZigW7ZVqrxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83109 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1602026|ensemblbacteria:AAC65067 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y070_trepa(display_long)|uniprotkb:TP_0070(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602035|imex:IM-9152-2307 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) refseq:WP_010881519.1|ensemblbacteria:AAC65067(transcript)|ensemblbacteria:TP_0070(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0070; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:91G4IIKloeuW7UsLhmi6pcif0zk243276 intact-crc:862A6714FDACDDCB|rigid:ADv67ue33qdOSCMZ3cdeOdoJcfA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83109 uniprotkb:O83958 intact:EBI-1602026|ensemblbacteria:AAC65067 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y070_trepa(display_long)|uniprotkb:TP_0070(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602041|imex:IM-9152-2308 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881519.1|ensemblbacteria:AAC65067(transcript)|ensemblbacteria:TP_0070(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0070; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:91G4IIKloeuW7UsLhmi6pcif0zk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8859B66DCD323DD0|rigid:RZWOOQ5xObUote3DyfYKq1M88sA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83799 uniprotkb:O83969 intact:EBI-1602051|ensemblbacteria:AAC65800|ensemblbacteria:AGN75997 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83799_trepa(display_long)|uniprotkb:TP_0827(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602047|imex:IM-9152-2309 author score:0.357409441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012505(YbbR-like)|ensemblbacteria:AAC65800(transcript)|ensemblbacteria:AGN75997(transcript)|ensemblbacteria:TP_0827(gene)|ensemblbacteria:TPANIC_0827(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0827; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DEX30gNevap6wjkSkWUqH3zdwco243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:0EAD3A64053CE3D1|rigid:obJnrRmIgVpTt0Ij7lm3p2WABD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83799 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1602051|ensemblbacteria:AAC65800|ensemblbacteria:AGN75997 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83799_trepa(display_long)|uniprotkb:TP_0827(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602056|imex:IM-9152-2310 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR012505(YbbR-like)|ensemblbacteria:AAC65800(transcript)|ensemblbacteria:AGN75997(transcript)|ensemblbacteria:TP_0827(gene)|ensemblbacteria:TPANIC_0827(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0827; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:DEX30gNevap6wjkSkWUqH3zdwco243276 intact-crc:11E24BFF0EB8041B|rigid:skOiSwaaXSTeGlQSPsF6IA8e798 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83799 uniprotkb:O83282 intact:EBI-1602051|ensemblbacteria:AAC65800|ensemblbacteria:AGN75997 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83799_trepa(display_long)|uniprotkb:TP_0827(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602062|imex:IM-9152-2311 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012505(YbbR-like)|ensemblbacteria:AAC65800(transcript)|ensemblbacteria:AGN75997(transcript)|ensemblbacteria:TP_0827(gene)|ensemblbacteria:TPANIC_0827(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0827; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DEX30gNevap6wjkSkWUqH3zdwco243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:54DDDE9ABC4A9C9C|rigid:zKLQEOf6qKv5jsJQbRzZvPh0I2U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83540 uniprotkb:O83398 intact:EBI-1602068|ensemblbacteria:AAC65515 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602072|imex:IM-9152-2312 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:3F1E807BE1C450DB|rigid:TwddAR+eDad2//xfKrTsOUcOrPQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83540 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1602068|ensemblbacteria:AAC65515 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602078|imex:IM-9152-2313 author score:0.285363151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 intact-crc:67047468A51832B4|rigid:vGGvgSqBOMBJy7uorsxj5A54Wt8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83540 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1602068|ensemblbacteria:AAC65515 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602084|imex:IM-9152-2314 author score:0.279904694 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 intact-crc:72FB8525C2DD80B4|rigid:2ASYkMrvlYLBJ2vGWtpqM9R0pRE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83540 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1602068|ensemblbacteria:AAC65515 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602090|imex:IM-9152-2315 author score:0.248529713 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 intact-crc:704C217A90E8D334|rigid:aoJ9j+EQ0iIF6pzQdvyikePzWoc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83540 uniprotkb:O83667 intact:EBI-1602068|ensemblbacteria:AAC65515 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602096|imex:IM-9152-2316 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:8DD04C90BA7A7BBA|rigid:bDtECIxDeHeUylDP6LvNdaAP/74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83540 uniprotkb:O83954 intact:EBI-1602068|ensemblbacteria:AAC65515 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602102|imex:IM-9152-2317 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:ADE07FCE90F6F212|rigid:M1EnvkNIasxfyMGY+62omDI4eQc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83540 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1602068|ensemblbacteria:AAC65515 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:vatb2_trepa(display_long)|uniprotkb:atpB2(gene name)|psi-mi:atpB2(display_short)|uniprotkb:V-ATPase subunit B 2(gene name synonym)|uniprotkb:TP_0528(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602108|imex:IM-9152-2318 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|interpro:IPR027417|refseq:WP_010881976.1|ensemblbacteria:AAC65515(transcript)|ensemblbacteria:TP_0528(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0528; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:jQfInwxKUuSpsRSD+Tzp6sCc6Mw243276 intact-crc:D8F20C5B723B43D6|rigid:iunkKhCt+QjWBgEAtpwTePlz+b0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83982 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602117|imex:IM-9152-2319 author score:0.355501686 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:EEFC0B7A657BD8F8|rigid:Prt5cVKHLqE4nsSG4o+uHxX5ogg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83413 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602123|imex:IM-9152-2320 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:2EE898A941108BB3|rigid:hyzz+NN7b3w9Wu/BKgMpCVRWgpU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83667 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602129|imex:IM-9152-2321 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:0920BF186141D8ED|rigid:UjqUHtyer5h/hAQJaEsePZwjeKw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83767 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602135|imex:IM-9152-2322 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:68B491C32B3EF34E|rigid:uvCDGI6rBiDzRyWY9gb+Loe1wBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83745 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602141|imex:IM-9152-2323 author score:0.06996641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:D648395819242C3D|rigid:D9jiLY3DJZ5bHpah+fPIr/pZMLo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83306 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1602114|ensemblbacteria:AAC65279 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602147|imex:IM-9152-2324 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 intact-crc:1BA1CE73CD7B0664|rigid:+IIwgnw3Xxs5sDtblPfGqrflNUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83306 uniprotkb:O83958 intact:EBI-1602114|ensemblbacteria:AAC65279 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y282_trepa(display_long)|uniprotkb:TP_0282(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602153|imex:IM-9152-2325 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010881731.1|ensemblbacteria:AAC65279(transcript)|ensemblbacteria:TP_0282(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0282; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:5SaTzO2w4egY1jnHnsgSQjT4G6U243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:5C02FFD3A900E081|rigid:N+G5utdKe7WpSionuH0s+3YvgTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83645 uniprotkb:P21992 intact:EBI-1602159|ensemblbacteria:AAC65625 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y638_trepa(display_long)|uniprotkb:TP_0638(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602162|imex:IM-9152-2326 author score:0.355275687 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882083.1|ensemblbacteria:AAC65625(transcript)|ensemblbacteria:TP_0638(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0638; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:DclK57Xno4ct4Q8AHFs56h8wPjI243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:3EFB62BAC0E44987|rigid:Mg2AZWGCDd8lN71xsQ0oOy9lfLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83808 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1602168|ensemblbacteria:AAC65808 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y836_trepa(display_long)|uniprotkb:TP_0836(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602171|imex:IM-9152-2327 author score:0.355275687 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 refseq:WP_010882280.1|ensemblbacteria:AAC65808(transcript)|ensemblbacteria:TP_0836(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0836; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:zbxv3PPVddbQZUQuKopRep+s52c243276 intact-crc:2074C11D27073630|rigid:20I1vDiHhgg5FVd2tmp8meczux4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83866 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1582364|ensemblbacteria:AAC65866 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y896_trepa(display_long)|uniprotkb:TP_0896(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602177|imex:IM-9152-355 author score:0.353260356 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65866(transcript)|ensemblbacteria:TP_0896(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0896; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:eaoIVijCat8PdDxAr4wmCfeAnnM243276 intact-crc:9B438E7CCC5C9C87|rigid:RNVhbnFlJCJ7d6AMDNH8JlgjfIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83866 uniprotkb:O83927 intact:EBI-1582364|ensemblbacteria:AAC65866 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y896_trepa(display_long)|uniprotkb:TP_0896(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602183|imex:IM-9152-356 author score:0.31148288 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65866(transcript)|ensemblbacteria:TP_0896(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0896; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:eaoIVijCat8PdDxAr4wmCfeAnnM243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:A27D95B0A05971A6|rigid:A38H5M0HCKR24lnWk655ubn1saI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83210 uniprotkb:O83662 intact:EBI-1602189|ensemblbacteria:AAC65195 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:y180_trepa(display_long)|uniprotkb:TP_0180(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602195|imex:IM-9152-357 author score:0.348364706 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65195(transcript)|ensemblbacteria:TP_0180(gene) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0180|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QWJPxF2TxFL0o5ZJFSQYPyW+Rg0243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:C7319FCBEE572CAF|rigid:xdWOOoC2Y6B8E6F6dVJxpEBlCdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83960 uniprotkb:O83662 intact:EBI-1583870|ensemblbacteria:AAC26583 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83960_trepa(display_long)|uniprotkb:TP_0995(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602201|imex:IM-9152-358 author score:0.324334004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|ensemblbacteria:AAC26583(transcript)|ensemblbacteria:TP_0995(gene)|interpro:IPR036890 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0995|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:e/7IeUNCDYEoLFDH9to3t6L3g3E243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:F88FBA060EAA5AA1|rigid:1h6cgB1yqJmW4rOS5TNEm961PsM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83662 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602207|imex:IM-9152-359 author score:0.318462297 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:964B5991F2EE2FCE|rigid:AGctp7yZfrBY8faYzlk73lytCMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83723 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602213|imex:IM-9152-360 author score:0.306891469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:FE15F12A9C18B291|rigid:lVD6pkwQ4j244QQ0CQgjQcIJpdA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83310 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1588258|ensemblbacteria:AAC65268 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602219|imex:IM-9152-361 author score:0.301194774 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 intact-crc:88F34CD1C08D91CD|rigid:WvtkBHyIbXLRPdp7XYWyVurCr/4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83647 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602225|imex:IM-9152-362 author score:0.301194774 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:2146A17BC8DE03BE|rigid:6cy2tv21lWkV2ScAxJBTrQVlzG4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83119 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602231|imex:IM-9152-363 author score:0.279024651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:C2E89FB5E4BAC96F|rigid:PxdONjIRDi8kDToPYqbglk721x8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83864 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602237|imex:IM-9152-364 author score:0.279024651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 intact-crc:799916BD1EA69BA1|rigid:ixMQDx8rH72Zn+5D+JbqZjF1g7k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83662 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602243|imex:IM-9152-365 author score:0.268322591 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:F8E25A81BC6CC055|rigid:HYBV00pfMuUkIgAGTGx88p4+72k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83106 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1582491|ensemblbacteria:AAC65060 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602249|imex:IM-9152-366 author score:0.247714381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 intact-crc:6276E816C165F57C|rigid:6l2Mp+/ba1brHKYQpoTyhBibqNU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O66106 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602255|imex:IM-9152-367 author score:0.247714381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:0EB0A78A9A70EF2C|rigid:GGTDztaCzqCunsXy/fsd2i1fO6Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83662 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602261|imex:IM-9152-368 author score:0.242731471 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:3108922A06F0E291|rigid:Bj8zr09pGljK2LUT2zn+7YQfcDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83098 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602267|imex:IM-9152-369 author score:0.237817107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:34D4B97D885E7A94|rigid:kvSXg1qv/+5Pj1PxrjEkSA4aY4U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O66107 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602273|imex:IM-9152-370 author score:0.237817107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:0F27184E99DDB9A4|rigid:R3pnXwxiqSUTg0QEPaZvfIC34tA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83596 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602279|imex:IM-9152-371 author score:0.228195322 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:C65808F951E1E3FC|rigid:A5a/ZPc5BGYWgxQetw1Bz9CLVvY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83627 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602285|imex:IM-9152-372 author score:0.223488404 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:DE1562C6933ED519|rigid:lDTtzqGRbYfcUeA3BPCsoYgIG18 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83662 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602291|imex:IM-9152-373 author score:0.209785395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:DB52AA408C606CF6|rigid:z7cmi4FJMtCZotmb5UzJfg5N+AY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83662 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602297|imex:IM-9152-374 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:F3FEBF8E5DDA5928|rigid:4Gc020OopIemyM/MJGNK/lN3mTE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83662 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602303|imex:IM-9152-375 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:CFC0208A15E99BB7|rigid:8kWiIPVHfE/xJL3bwCyb0xSF968 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83752 uniprotkb:O83662 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602309|imex:IM-9152-376 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:B0515A2898EA34DB|rigid:hkKSvFXuZ4zBWSXw1PVDxDhNmRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83662 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602315|imex:IM-9152-377 author score:0.184259029 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:5FC83370EADB2A9F|rigid:RMExDRVR9uAQ/WtHVLPz7v3xgs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83670 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602321|imex:IM-9152-378 author score:0.180246724 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:873DB479A7FFF176|rigid:kOsQdfsODff2in+d4hY/4kYuFPA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83738 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602327|imex:IM-9152-379 author score:0.172427228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:711CDCC1D90ECB7F|rigid:Xhnscs0STvKO+XUV1LRUrxQHVg0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83662 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602333|imex:IM-9152-380 author score:0.089288693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:17BE2306B4CC587F|rigid:LXZ6P04fIyLuHgVHGVDNfP3Y7m4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83398 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602339|imex:IM-9152-381 author score:0.087123531 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:A3180A2E0615A992|rigid:yMgqYhJ72XOuC1SL3DCNaOgUIIY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83662 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602345|imex:IM-9152-382 author score:0.076995584 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:B9AE438703012E4E|rigid:h7Tkc7cKvcm19e1NPt6tpBMj1Kc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83969 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602351|imex:IM-9152-383 author score:0.069682556 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:C7121A03C0FF1EF4|rigid:gArV8fzTVtUh+yb0h1q5RIJMAIk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83662 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602357|imex:IM-9152-384 author score:0.027631324 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:310E43D1895D64C1|rigid:3XFMzLhCS9vBxavvwHL8s+9Br24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83662 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602363|imex:IM-9152-385 author score:0.024880519 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:CE850735C9F1FABF|rigid:+PLr4hzaGe4Ah2iAqrCXtxXgLjo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83662 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602369|imex:IM-9152-386 author score:0.022994386 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:3BA2E9F6D1552CA8|rigid:qPEzYvkK0zYZxZEQ8VsmEtKHz6Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83662 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602375|imex:IM-9152-387 author score:0.015472776 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:7C0A4AB4DB344775|rigid:1s0uU9tJwV1nAr+U9RsmRELSxtM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83662 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602381|imex:IM-9152-388 author score:0.012849257 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:1FD6EF719B9383BE|rigid:856yAeiC3JgW19rU9ESgy1NlQvc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83662 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602399|imex:IM-9152-391 author score:0.000255453 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:80F12B77282E15BB|rigid:0fo/smBuatELxyjxsrzeWW/NduY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83662 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1602192|ensemblbacteria:AAC65639 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602387|imex:IM-9152-389 author score:0.005184412 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 intact-crc:7B7E449A30D400F9|rigid:QdzrovIUEcc1HBKhm0X3ymKOC68 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83662 uniprotkb:O83954 intact:EBI-1602192|ensemblbacteria:AAC65639 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y656_trepa(display_long)|uniprotkb:TP_0656(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602393|imex:IM-9152-390 author score:0.004297743 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65639(transcript)|ensemblbacteria:TP_0656(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0656; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7r1XlZ1BWA+lXmH+u1K/fQtFz2E243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:D1164969CC757523|rigid:QXZezEu3NT9DhFTukH4jBHYmUBI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83116 uniprotkb:O83099 intact:EBI-1586088|ensemblbacteria:AAC65072|ensemblbacteria:AGN75296 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83116_trepa(display_long)|uniprotkb:TP_0077(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602405|imex:IM-9152-392 author score:0.347134018 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003869(Polysaccharide biosynthesis protein CapD)|ensemblbacteria:AAC65072(transcript)|ensemblbacteria:AGN75296(transcript)|ensemblbacteria:TP_0077(gene)|ensemblbacteria:TPANIC_0077(gene)|refseq:WP_010881526.1|interpro:IPR036291 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0077; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:O3zntxZ5EpPqtPsSVRaDA4jn/4o243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:2619B08202D6E27A|rigid:LRmtgkJ2cLWkQtRNNW/vGyWBmwE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83116 uniprotkb:O83958 intact:EBI-1586088|ensemblbacteria:AAC65072|ensemblbacteria:AGN75296 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83116_trepa(display_long)|uniprotkb:TP_0077(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602411|imex:IM-9152-393 author score:0.003399518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003869(Polysaccharide biosynthesis protein CapD)|ensemblbacteria:AAC65072(transcript)|ensemblbacteria:AGN75296(transcript)|ensemblbacteria:TP_0077(gene)|ensemblbacteria:TPANIC_0077(gene)|refseq:WP_010881526.1|interpro:IPR036291 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0077; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:O3zntxZ5EpPqtPsSVRaDA4jn/4o243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:870D478F019BFDF1|rigid:x5EjNCplRfrqSv50PTBpA7esiMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83057 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1602417|ensemblbacteria:AAC65013 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y013_trepa(display_long)|uniprotkb:TP_0013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602420|imex:IM-9152-394 author score:0.34315171 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR024258|ensemblbacteria:AAC65013(transcript)|ensemblbacteria:TP_0013(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0013; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:PuM/7WTroK38DOC/a9u7vhYN85w243276 intact-crc:CC77DCA27A8902B4|rigid:ujaAOxBrK+Ves6KkPdDe5fDoge8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83057 uniprotkb:O83877 intact:EBI-1602417|ensemblbacteria:AAC65013 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y013_trepa(display_long)|uniprotkb:TP_0013(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602426|imex:IM-9152-395 author score:0.165413283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65013(transcript)|ensemblbacteria:TP_0013(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0013; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PuM/7WTroK38DOC/a9u7vhYN85w243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:84764BA48F9EC50F|rigid:9iCuVPmkxmg2nzlqKJyaRKqL3mo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83057 uniprotkb:O83745 intact:EBI-1602417|ensemblbacteria:AAC65013 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y013_trepa(display_long)|uniprotkb:TP_0013(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602432|imex:IM-9152-396 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65013(transcript)|ensemblbacteria:TP_0013(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0013; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PuM/7WTroK38DOC/a9u7vhYN85w243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:FFEB997A5ED17EC5|rigid:YEkm/dRI9SVGQLh1oi1usFGD3t8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83057 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1602417|ensemblbacteria:AAC65013 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y013_trepa(display_long)|uniprotkb:TP_0013(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602438|imex:IM-9152-397 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR024258|ensemblbacteria:AAC65013(transcript)|ensemblbacteria:TP_0013(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0013; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:PuM/7WTroK38DOC/a9u7vhYN85w243276 intact-crc:0C3325C49AECE12A|rigid:Wp8XXA5AkL1EgkeIpQ5wOc6x0VE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83934 uniprotkb:O83969 intact:EBI-1586349|ensemblbacteria:AAC65926 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y968_trepa(display_long)|uniprotkb:TP_0968(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602444|imex:IM-9152-398 author score:0.34315171 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65926(transcript)|ensemblbacteria:TP_0968(gene)|refseq:WP_010882412.1 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0968; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bnUiwPhzNZ/mhlkGJYOYjO04XCo243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:5B0B3320B8B14FF2|rigid:tdud4MNT4Dbp3bj/DqX4kS1sQHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83934 uniprotkb:O83312 intact:EBI-1586349|ensemblbacteria:AAC65926 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:y968_trepa(display_long)|uniprotkb:TP_0968(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602450|imex:IM-9152-399 author score:0.325184226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65926(transcript)|ensemblbacteria:TP_0968(gene)|refseq:WP_010882412.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0968; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bnUiwPhzNZ/mhlkGJYOYjO04XCo243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:0193212126FDF8FB|rigid:VmYxlMc8r+aQlKG/hWigTsr8iKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83934 uniprotkb:O83745 intact:EBI-1586349|ensemblbacteria:AAC65926 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y968_trepa(display_long)|uniprotkb:TP_0968(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602456|imex:IM-9152-400 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65926(transcript)|ensemblbacteria:TP_0968(gene)|refseq:WP_010882412.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0968; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bnUiwPhzNZ/mhlkGJYOYjO04XCo243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:3936B3DAA75E84B9|rigid:X6sUjj8bSXDRbix8bxqrUG2/+Y8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83934 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586349|ensemblbacteria:AAC65926 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y968_trepa(display_long)|uniprotkb:TP_0968(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602462|imex:IM-9152-401 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65926(transcript)|ensemblbacteria:TP_0968(gene)|refseq:WP_010882412.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0968; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:bnUiwPhzNZ/mhlkGJYOYjO04XCo243276 intact-crc:6D273D372329DB6B|rigid:+TcsCi774m1eEHYcdKr6I7OerSs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83061 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602468|imex:IM-9152-402 author score:0.342204393 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0017; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 intact-crc:CA6D93920497845B|rigid:UQbdwZqYYvrfhoaQnczMtTVgUZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83061 uniprotkb:O83574 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602474|imex:IM-9152-403 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0017; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:B8525B2A5EDB0D36|rigid:Xb4jKpqGcck2B0zAPAwlcHL2NW4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83061 uniprotkb:O83667 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602480|imex:IM-9152-404 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0017; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:DD4DB4302DB382AF|rigid:tM7FZqEacET11S4ZghxgSiITZXs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83061 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602486|imex:IM-9152-405 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0017; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 intact-crc:00F5AA9BC8FA8FE7|rigid:le+V/CzGaBw7Y50vDvwubqIkyww false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83061 uniprotkb:O83958 intact:EBI-1589928|ensemblbacteria:AAC65009|ensemblbacteria:AGN75239 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83061_trepa(display_long)|uniprotkb:TP_0017(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602492|imex:IM-9152-406 author score:0.002313197 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65009(transcript)|ensemblbacteria:AGN75239(transcript)|ensemblbacteria:TP_0017(gene)|ensemblbacteria:TPANIC_0017(gene)|refseq:WP_010881466.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0017; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6IKwF2XZ5lolrGbBgWD/yKa/kT8243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:38E63022522A2FE8|rigid:PO8WZ/kougaW1+hJwiw1kwcw0Dc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83398 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602498|imex:IM-9152-407 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:70E81402E5982B98|rigid:Lb7P1AK8wMplemVWos3aey+1FtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83969 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602507|imex:IM-9152-408 author score:0.289071214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:6C53851E06404B79|rigid:7Vbtl26EFpXopAK6pqlRvatg+C0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83052 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1602502|ensemblbacteria:AAC65003 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602513|imex:IM-9152-409 author score:0.272759532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 intact-crc:006A7DE081F2C09D|rigid:M20gkSWSe9k7qeXeMNuJd8beXIU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83052 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1602502|ensemblbacteria:AAC65003 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602519|imex:IM-9152-410 author score:0.267451934 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 intact-crc:2A1B9BA63D9A65BE|rigid:uU4HTdRVDmCvE6sf/gWFO/+EHKA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83877 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602525|imex:IM-9152-411 author score:0.13364493 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:0715A42607A37A5A|rigid:FBbTsetGF+rpQA6LV8QfR2m5L/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83767 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602531|imex:IM-9152-412 author score:0.078608673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:A3CB206FF35C1E19|rigid:Fl9g1k1PWHbUH96JVm/DTAZ8hzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83745 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602537|imex:IM-9152-413 author score:0.065997631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:CA2F166105794B31|rigid:4x2gIBbvtEC/hKYNDddddqtmuvE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83052 uniprotkb:O83282 intact:EBI-1602502|ensemblbacteria:AAC65003 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y007_trepa(display_long)|uniprotkb:TP_0007(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602543|imex:IM-9152-414 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024258|ensemblbacteria:AAC65003(transcript)|ensemblbacteria:TP_0007(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0007; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:R+80/IfrboVliasM9pXFX1VaBkw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8F1EE452360E5EF1|rigid:i/DA+RMqB9XAVfmQPwtg19hus7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83851 uniprotkb:O83398 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602552|imex:IM-9152-415 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:3363791BC9DEC18B|rigid:o4qXoA8iGrGRU6y/hRKW6EFZqw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83851 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602558|imex:IM-9152-416 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 intact-crc:E234018649F27B05|rigid:PidBLBxdrVhSCAcM3hm9WDgGt8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83851 uniprotkb:O83531 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602564|imex:IM-9152-417 author score:0.31169449 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:71A13C8D20C4745D|rigid:Enh3fjNa2WY6SiqvlWveR/jcT/I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83851 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602576|imex:IM-9152-419 author score:0.121660562 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 intact-crc:BFA8A1563A2FFAED|rigid:6I/SxYeYYItVgpEKjUP5NxxqB+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83851 uniprotkb:O83969 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602570|imex:IM-9152-418 author score:0.289071214 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:53D90EA4C847996A|rigid:+yMV/VV8HiRpI3uaS0NJP0s+ON0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83851 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602582|imex:IM-9152-420 author score:0.065997631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 intact-crc:418A199CBAF30349|rigid:n6/fmAbZExjRmDnP7x00C5fu+Xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83851 uniprotkb:O83954 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602588|imex:IM-9152-421 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1005C8955A27CDAE|rigid:9QlZ0Giv1PCadbmYrREFYXVWddI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83935 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1602604|ensemblbacteria:AAC65927 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602600|imex:IM-9152-423 author score:0.34127964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 intact-crc:BAAA7BB4EE94D207|rigid:9l0iFFdKP+JmQJVsJ243GDlnGcA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83851 uniprotkb:O83958 intact:EBI-1602549|ensemblbacteria:AAC65843|ensemblbacteria:AGN76050 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83851_trepa(display_long)|uniprotkb:TP_0881(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602594|imex:IM-9152-422 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|refseq:WP_010882324.1|ensemblbacteria:AAC65843(transcript)|ensemblbacteria:AGN76050(transcript)|ensemblbacteria:TP_0881(gene)|ensemblbacteria:TPANIC_0881(gene)|go:"GO:0005524"(ATP binding) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0881; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AbujcBqctLq9Li8MXygxuLnLdew243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:766CA2B66CC5881C|rigid:30M4jSLNMVN620aCZydr5FPiyto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83935 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1602604|ensemblbacteria:AAC65927 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602609|imex:IM-9152-424 author score:0.31169449 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 intact-crc:002DE280AF5CC1EA|rigid:Fz+bCtrVwt/dwgNL4iMtVvOsCQ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83935 uniprotkb:O83574 intact:EBI-1602604|ensemblbacteria:AAC65927 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602621|imex:IM-9152-426 author score:0.196009199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:2375245D91C5F918|rigid:GX6p6gDDLPecJp0weY2hKNDBB0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83935 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1602604|ensemblbacteria:AAC65927 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602615|imex:IM-9152-425 author score:0.272759532 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 intact-crc:9F83FE3A41820E28|rigid:wzGINabuJ4unJE/hIM62naSjN7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83935 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1602604|ensemblbacteria:AAC65927 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602627|imex:IM-9152-427 author score:0.065997631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 intact-crc:B977AD630F7292FA|rigid:8Z4eE6sFbm+QRR9URj0aVY3bWHU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83935 uniprotkb:O83282 intact:EBI-1602604|ensemblbacteria:AAC65927 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602633|imex:IM-9152-428 author score:0.027512298 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:EA5924B662B70C2D|rigid:f9rNLTh5m9lX8HQi+EnxmRE9a1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83935 uniprotkb:O83954 intact:EBI-1602604|ensemblbacteria:AAC65927 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602639|imex:IM-9152-429 author score:0.022894864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1AA16ECED08EA201|rigid:x0aWxEt2lxv4lTPL+MGNp3HeVhQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83935 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1602604|ensemblbacteria:AAC65927 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y969_trepa(display_long)|uniprotkb:TP_0969(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602645|imex:IM-9152-430 author score:0.001385176 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65927(transcript)|ensemblbacteria:TP_0969(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0969; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:TH9FqDCWvli9qpFjVO2cdsUcB90243276 intact-crc:7CC804EDE66CE7B3|rigid:7jQI3SiWOhavjDUFJN5rUPYaPr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83508 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1602655|ensemblbacteria:AAC65490 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y495_trepa(display_long)|uniprotkb:TP_0495(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602666|imex:IM-9152-433 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65490(transcript)|ensemblbacteria:TP_0495(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0495; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:cDhR+gDqnn8nSJcyAXlAY0spjw4243276 intact-crc:0CABE146D469E9E4|rigid:Ig0E77rq98PxtuiWMggdJptFSOw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83508 uniprotkb:P21992 intact:EBI-1602655|ensemblbacteria:AAC65490 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y495_trepa(display_long)|uniprotkb:TP_0495(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602660|imex:IM-9152-432 author score:0.3271204 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65490(transcript)|ensemblbacteria:TP_0495(gene) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0495; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cDhR+gDqnn8nSJcyAXlAY0spjw4243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:3CE32E2F625CF30E|rigid:TDnCnCiFu+TZWvIh51S1JdGIj+0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83508 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1602655|ensemblbacteria:AAC65490 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:y495_trepa(display_long)|uniprotkb:TP_0495(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602651|imex:IM-9152-431 author score:0.339080801 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) ensemblbacteria:AAC65490(transcript)|ensemblbacteria:TP_0495(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0495; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:cDhR+gDqnn8nSJcyAXlAY0spjw4243276 intact-crc:99AF7097E720F8E3|rigid:yzp3i8bL/iwbG4ZsREZ01XD0/Yw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83133 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1585148|ensemblbacteria:AAC65099 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602678|imex:IM-9152-435 author score:0.312035335 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 intact-crc:79910F10C7275DD3|rigid:xfbbtV/ZgrJiicIgoqeje+t3q9M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83595 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198475|intact:EBI-1581824|ensemblbacteria:AAC65562 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:syl_trepa(display_long)|uniprotkb:leuS(gene name)|psi-mi:leuS(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0586(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602672|imex:IM-9152-434 author score:0.337027814 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR025709|refseq:WP_010882032.1|ensemblbacteria:AAC65562(transcript)|ensemblbacteria:TP_0586(gene)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0586|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:ONh8uF5GAn9X2EjxFHo49hgjDMM243276 intact-crc:7D1AAEC9ED9C28DA|rigid:xirKY0ugVTgTPEzLt4IN87NfJVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83913 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602690|imex:IM-9152-437 author score:0.26778395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:A5ED7702BE8610F9|rigid:HoPW6FnNratAAzNUmxTziooFJbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83931 uniprotkb:O83087 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602684|imex:IM-9152-436 author score:0.283038227 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:B867D4EE9D0CFAFE|rigid:69rWjW8FJgx/CHeWEj2aUVSMxJA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83087 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602696|imex:IM-9152-438 author score:0.254723179 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:4EA993A14559085E|rigid:Qo/QZpSceK6sa+qpAdKxHCyz2HI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83361 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602702|imex:IM-9152-439 author score:0.225193063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:04605E59D9674570|rigid:s5c7SjDcW2AQQDCoSLtnESlc2Kk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83864 uniprotkb:O83087 intact:EBI-1582697|ensemblbacteria:AAC65851|ensemblbacteria:AGN76063 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83864_trepa(display_long)|uniprotkb:TP_0894(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602714|imex:IM-9152-441 author score:0.220530377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025605|interpro:IPR021139|ensemblbacteria:AAC65851(transcript)|ensemblbacteria:AGN76063(transcript)|ensemblbacteria:TP_0894(gene)|ensemblbacteria:TPANIC_0894(gene)|refseq:WP_010882337.1|interpro:IPR041966 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0894|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:B4Wy2o+XpOdh8o+zZ/Msh/rBOYM243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:1B3EE37F36143782|rigid:46JDVoVnDIh5/4EqDmQ9Sc+G5fo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83634 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602708|imex:IM-9152-440 author score:0.225193063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:FA37C668DE174575|rigid:T4ykr+QfQqAqGfIY7W6YTBbSdvo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83986 uniprotkb:O83087 intact:EBI-1585764|ensemblbacteria:AAC65974 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602720|imex:IM-9152-442 author score:0.220530377 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:69C2BEC9992D9372|rigid:p3h8it6VJT0Dw4uG61VNPOiBUrw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83087 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602726|imex:IM-9152-443 author score:0.211413992 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:3D5930D163FD22B3|rigid:r6dgpYAP972LystsVK9rmd73x1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83087 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602732|imex:IM-9152-444 author score:0.211312573 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:89ED03BA24E7A6AF|rigid:4sG/y4hyq3zDcGM8UcKnHeoVVgg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83087 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602738|imex:IM-9152-445 author score:0.202049195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:A1756E4F4BCCDAC0|rigid:OoI4qs3bKmzLzwR3woBHPp7rhv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83087 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602750|imex:IM-9152-447 author score:0.185736038 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:328AF409B76ACF74|rigid:9ArZGdnOV97Zi/y0n1JTHLEs4d0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83087 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602744|imex:IM-9152-446 author score:0.194017585 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:A8F26B0A610F085C|rigid:Dh6w9jw9zFPRsyyrO1xrHnIZ39E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83087 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602756|imex:IM-9152-448 author score:0.185736038 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:2C1510EEE9B90756|rigid:y/Is/ZB0zgzsQG3XxP9E/Y80Wiw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83087 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602762|imex:IM-9152-449 author score:0.177730034 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:E3606DCCAAA5844D|rigid:dqvjmN5Ab67nRCB6Zlo1N+e2q8E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83087 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602768|imex:IM-9152-450 author score:0.173829605 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:2D8DC4CA2CBEDABF|rigid:tZUb/UmUfu8KrbVvEoP34nD3GQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83752 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602786|imex:IM-9152-453 author score:0.151837631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:48F64120FA2B6DD5|rigid:8DM7TAXbumyArXZQW0LXgSrFIaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83087 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602780|imex:IM-9152-452 author score:0.162534071 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:A522D71C3418FCF3|rigid:TugPVwnu1hMT5GorvGjgGhtamRg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83570 uniprotkb:O83087 intact:EBI-1585774|ensemblbacteria:AAC26563 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602774|imex:IM-9152-451 author score:0.166232045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:7A26F70F84A31490|rigid:QstZikeBPFjGVd04HYkZNpX9s2w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83565 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602792|imex:IM-9152-454 author score:0.141725999 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:3B1D322BC015ADBB|rigid:yDZWP8YDQ/nBd8Pb2mc6uLC4W2o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83087 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602798|imex:IM-9152-455 author score:0.138482636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:6E54E5110813E63A|rigid:MnlPCuNZYJ5J/pqAMT2ZTz8x3kA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83087 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602804|imex:IM-9152-456 author score:0.109371697 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:F2E4744EF5541714|rigid:7EhxixCII6aU+1CUjoAyMXTcEJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83087 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602810|imex:IM-9152-457 author score:0.104235949 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:7BA99FB989279E17|rigid:IYewGoxtxpqTohMawlL2ZHzZ858 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83463 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602816|imex:IM-9152-458 author score:0.092319894 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:3CE207B5D93468BF|rigid:O77jD8T2semFRAMv/rUfTk8lCdU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83087 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602822|imex:IM-9152-459 author score:0.07029005 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:63B23DA737B03F91|rigid:tjwJpU8AqS3ZvZ4FdxfBsTlQDrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83398 uniprotkb:O83087 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602834|imex:IM-9152-461 author score:0.065219879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:F785BD67ECB15980|rigid:q7+obu21Kc1I76900pqL+gVk8Og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83982 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602840|imex:IM-9152-462 author score:0.065219879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:1802F91C4F07E1C1|rigid:WM4j/wEDkyQyxFw0U78NPOcGAao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83305 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602828|imex:IM-9152-460 author score:0.06688058 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:7DDA11B87FCBA6A6|rigid:kLtcrZwmgQYgEbRLZIJdhrAIp6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83531 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602846|imex:IM-9152-463 author score:0.05747787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:FF4C6C778A769F27|rigid:kP4otnm/+DrVF026qdvJuh9X0Xg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83087 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602852|imex:IM-9152-464 author score:0.051914365 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:32283C11D6FBEF9F|rigid:aG1Am2UPFeMgr6lYQuCHocRbFVg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83087 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602864|imex:IM-9152-466 author score:0.031787565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:7922B04DC74CF0C0|rigid:9xUFpgSIwrkIzdkltVSXx9/4dzU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83087 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602858|imex:IM-9152-465 author score:0.046862597 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:5C30E3372D7787B0|rigid:mt8tlRQLCwJbLaeT1sqSMyKK7oY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83087 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602876|imex:IM-9152-468 author score:0.018311436 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:0637247CFF8B4C2F|rigid:dervQoE+kVPSs5SSEJ5K7wtMVsg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83087 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602870|imex:IM-9152-467 author score:0.020351117 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:393F8119428057E6|rigid:ZaWadbwFlSogtjonYMBruDfOlJI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83767 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602888|imex:IM-9152-815 author score:0.01135864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:E00902C7888C982A|rigid:cPg3kGVhrazJnhmrFJVXzPmgj2g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83667 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602882|imex:IM-9152-469 author score:0.016914651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:48EB172C14046E6B|rigid:Vqf1QLwrrYLlcqW0G8KsU3/nqNU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83087 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602894|imex:IM-9152-472 author score:0.009426023 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:CF8F7366B79B1661|rigid:y0hPklqhPinUiRoc+2HytooAD/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83087 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602900|imex:IM-9152-473 author score:0.003145501 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 intact-crc:8A976A8E45A681CF|rigid:OkxtfEIWxdG9RbAmpS1jzhJQ8Cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83087 uniprotkb:O83958 intact:EBI-1198740|intact:EBI-1585854|ensemblbacteria:AAC65044|ensemblbacteria:AGN75268 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83087_trepa(display_long)|uniprotkb:TP_0048(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602906|imex:IM-9152-474 author score:0.000186761 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007607(Protein of unknown function DUF583)|refseq:WP_010881497.1|ensemblbacteria:AAC65044(transcript)|ensemblbacteria:AGN75268(transcript)|ensemblbacteria:TP_0048(gene)|ensemblbacteria:TPANIC_0048(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0048; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AQsxDd6qTESwedHZO5mioxS9jnk243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:4CBB27C1E30A7B85|rigid:ysEFcEkln56jnkgYN8ujZBLICD8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83111 uniprotkb:O83099 intact:EBI-1602912|ensemblbacteria:AAC65068|ensemblbacteria:AGN75291 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83111_trepa(display_long)|uniprotkb:TP_0072(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602915|imex:IM-9152-475 author score:0.333073726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002109(Glutaredoxin)|interpro:IPR017167(Uncharacterised conserved protein UCP037291, glutaredoxin-related)|refseq:WP_010881521.1|ensemblbacteria:AAC65068(transcript)|ensemblbacteria:AGN75291(transcript)|ensemblbacteria:TP_0072(gene)|ensemblbacteria:TPANIC_0072(gene)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR036249 interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0072; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xHg2aSgo3Rwa7DoUDGEMQAsAsOs243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:37E5C99A5B51751F|rigid:rWsSsZX9u7A+45YpicRpWDh1TCs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83111 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1602912|ensemblbacteria:AAC65068|ensemblbacteria:AGN75291 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83111_trepa(display_long)|uniprotkb:TP_0072(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602921|imex:IM-9152-476 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR002109(Glutaredoxin)|interpro:IPR017167(Uncharacterised conserved protein UCP037291, glutaredoxin-related)|refseq:WP_010881521.1|ensemblbacteria:AAC65068(transcript)|ensemblbacteria:AGN75291(transcript)|ensemblbacteria:TP_0072(gene)|ensemblbacteria:TPANIC_0072(gene)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR036249 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0072; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:xHg2aSgo3Rwa7DoUDGEMQAsAsOs243276 intact-crc:B9B35B6585207BCD|rigid:qXhVEYAXDuw+CEaCZouEAUunuog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83521 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1602937|ensemblbacteria:AAC65496 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:clpx_trepa(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:TP_0508(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602933|imex:IM-9152-478 author score:0.333073726 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR003959(AAA ATPase, core)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR019489|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR027417|interpro:IPR038366|refseq:WP_010881957.1|ensemblbacteria:AAC65496(transcript)|ensemblbacteria:TP_0508(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0508; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:6PiecJsCqqb30G12KtXAbK5ZedY243276 intact-crc:33F579215B5FA80F|rigid:FI6pSzjSrfdTJ7zfhNjE+GA6EDc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83111 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1602912|ensemblbacteria:AAC65068|ensemblbacteria:AGN75291 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83111_trepa(display_long)|uniprotkb:TP_0072(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602927|imex:IM-9152-477 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR002109(Glutaredoxin)|interpro:IPR017167(Uncharacterised conserved protein UCP037291, glutaredoxin-related)|refseq:WP_010881521.1|ensemblbacteria:AAC65068(transcript)|ensemblbacteria:AGN75291(transcript)|ensemblbacteria:TP_0072(gene)|ensemblbacteria:TPANIC_0072(gene)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR036249 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0072; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:xHg2aSgo3Rwa7DoUDGEMQAsAsOs243276 intact-crc:EA93B5E66960685D|rigid:t/fUZsqxXPyN92Ne1HBHB+oZ6to false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83927 uniprotkb:O83521 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 intact:EBI-1602937|ensemblbacteria:AAC65496 psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:clpx_trepa(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:TP_0508(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602943|imex:IM-9152-479 author score:0.298207024 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR003959(AAA ATPase, core)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR019489|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR027417|interpro:IPR038366|refseq:WP_010881957.1|ensemblbacteria:AAC65496(transcript)|ensemblbacteria:TP_0508(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0508; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 rogid:6PiecJsCqqb30G12KtXAbK5ZedY243276 intact-crc:6DC00AC8493D02F2|rigid:KTUxiKMVY2VQoeR23caIQQhRPQA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83521 uniprotkb:O83954 intact:EBI-1602937|ensemblbacteria:AAC65496 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:clpx_trepa(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:TP_0508(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602949|imex:IM-9152-480 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003959(AAA ATPase, core)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR019489|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR027417|interpro:IPR038366|refseq:WP_010881957.1|ensemblbacteria:AAC65496(transcript)|ensemblbacteria:TP_0508(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0508; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6PiecJsCqqb30G12KtXAbK5ZedY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:BD13A57809121D9A|rigid:X4DVJhSEXkt5VoAKUiCPNnk9HqQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83785 uniprotkb:O83449 intact:EBI-1584132|ensemblbacteria:AAC65776 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:rl32_trepa(display_long)|uniprotkb:rpmF(gene name)|psi-mi:rpmF(display_short)|uniprotkb:TP_0807(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602955|imex:IM-9152-481 author score:0.33026151 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002677(Ribosomal protein L32p)|interpro:IPR011332(Ribosomal protein, zinc-binding)|ensemblbacteria:AAC65776(transcript)|ensemblbacteria:TP_0807(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|refseq:WP_010882252.1 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0807|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2b7FE8wqA771y9032aVgsEVBpQM243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:0D342F43CC17DE58|rigid:csXnOaJ8yOv3390T923wD4RMhfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O07884 uniprotkb:O83449 intact:EBI-1198798|intact:EBI-1582455|ensemblbacteria:AAC65692 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:flge_trepa(display_long)|uniprotkb:flgE(gene name)|psi-mi:flgE(display_short)|uniprotkb:TP_0727(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602964|imex:IM-9152-482 author score:0.324334004 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882172.1|interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR011491(Flagellar basal body FlaE)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR019776|interpro:IPR020013|interpro:IPR037925|ensemblbacteria:AAC65692(transcript)|ensemblbacteria:TP_0727(gene)|go:"GO:0009425"(bacterial-type flagellum basal body)|interpro:IPR037058 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0727|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hOE7G2FnYhkT9hRfVfMWC/qudDM243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:01B85F9826573E25|rigid:1qKyw2+ytn29OVzAcY/qpmYOFko false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83478 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602970|imex:IM-9152-483 author score:0.312647703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 intact-crc:BD857F7FB510A2C2|rigid:UIySSe3/RyyiytU1uVN70mhr8YM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83723 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1587106|ensemblbacteria:AAC65710 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602982|imex:IM-9152-485 author score:0.306891469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 intact-crc:9C140F1DE71AD257|rigid:xXbJVbJuTgERj0LygaWGXNjS9sI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83475 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602976|imex:IM-9152-484 author score:0.306891469 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0463|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:A6902D48AD4DB977|rigid:unEqehvY0SNJFfZzQsa3d/Mnfcg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83361 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602994|imex:IM-9152-487 author score:0.284472725 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:1EEFBF42B8BF7E75|rigid:hWj2NN9nLuEafzk6XPyPPutD+pc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83119 uniprotkb:O83449 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603000|imex:IM-9152-488 author score:0.279024651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:EA93D5E4D288A5B4|rigid:xmfESP6Oha5m0e/9gCSUXH+kExc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83647 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1602988|imex:IM-9152-486 author score:0.301194774 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:CEABB695463D3246|rigid:GkeVAgjvl41BI2KWpFKLDWIi+R8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83986 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603006|imex:IM-9152-489 author score:0.279024651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:6964B53CCA9D5F97|rigid:C/sk57eEe1HWY3SHHXEkYhPtDbA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83977 uniprotkb:O83449 intact:EBI-1583534|ensemblbacteria:AAC65964 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:ch10_trepa(display_long)|uniprotkb:groES(gene name)|psi-mi:groES(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin-10(gene name synonym)|uniprotkb:groS(gene name synonym)|uniprotkb:TP_1013(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603012|imex:IM-9152-490 author score:0.273641013 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65964(transcript)|ensemblbacteria:TP_1013(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|interpro:IPR020818|interpro:IPR018369|interpro:IPR011032(GroES-like)|refseq:WP_010882457.1|interpro:IPR037124 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_1013|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:PfWugdGoY0whDsLkmAgQZHRJ/g4243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:050B49C2110EC3EB|rigid:pv7E0N1dB8Q8o/xXz9nSbtVr2Tk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:Q08255 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603018|imex:IM-9152-491 author score:0.268322591 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:9FD1D886E73E6119|rigid:PCmv6yYifR4/1PerxrYTW+AJSek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83449 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603024|imex:IM-9152-492 author score:0.247714381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:730F7765F882F793|rigid:jNImNRIyINZk1F18Vupmrwoyjac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83098 uniprotkb:O83449 intact:EBI-1582702|ensemblbacteria:AAC65063 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603036|imex:IM-9152-494 author score:0.237817107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:1CAFF32CBE6C164F|rigid:4nL2l2CkS+3y114M4DJ2DVKlx/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O66106 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603030|imex:IM-9152-493 author score:0.247714381 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:26CBEDDBAC4283F7|rigid:pdIu92zRW0c5KSNP4vXX1U42ILU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83939 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603048|imex:IM-9152-496 author score:0.228195322 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 intact-crc:D3EE78492D81B320|rigid:nHEYZeAQS/i6+Jnq0v+XoZeoUnY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O66107 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603042|imex:IM-9152-495 author score:0.237817107 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:275C521FAFEFD57F|rigid:rddlzInrfpTDHZdqa+ogADo6Ggg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83627 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603054|imex:IM-9152-497 author score:0.223488404 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:CDFDF4F3BDFB8538|rigid:+4tVbCZ8yZNNUyLtjSoZVTOVk/Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83570 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603060|imex:IM-9152-498 author score:0.214283354 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:C90B989252506B7B|rigid:CFOp0411MTNZr+vDRWo6Pi7yqXk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83449 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603072|imex:IM-9152-500 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:F72AEA9B7B4B6141|rigid:lKtdM2NjKz7J1Zw/mkUaGozQmwM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83311 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603066|imex:IM-9152-499 author score:0.209785395 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:F329E011BA52002D|rigid:W5RTE8sc1eranFA5RO4fRQOmtY0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83532 uniprotkb:O83449 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603078|imex:IM-9152-501 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:308E3DAB53A30262|rigid:joxfkkWWdZNIsaqmWBMz77NQCz0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83752 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603084|imex:IM-9152-502 author score:0.196709735 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:D250A41FE3E8541D|rigid:zXwLNKkN17X14Q3cYRueUNpCuTU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83449 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603090|imex:IM-9152-503 author score:0.172427228 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:131D22F6A20CABB9|rigid:9G7uuVQ9k5JL9mm/ypEpJAy9G0M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83709 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603096|imex:IM-9152-504 author score:0.137318025 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:E6B45FB516C444A2|rigid:dEH3O1QtZLNPGGWXHf18Tp9tKx0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83449 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603102|imex:IM-9152-505 author score:0.089288693 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:3FC5695782FE34A4|rigid:EkXVY88uooEmJmjbcp7f/hfOSZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83398 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603108|imex:IM-9152-506 author score:0.087123531 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:8B63407F3027C549|rigid:m8Hyn+W/2JIPrS4fzMm0T95TYAk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83982 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603114|imex:IM-9152-507 author score:0.087123531 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:AA91B879B28166CD|rigid:fqOe+IMzMbiaJyuuQYekUaK55ds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83531 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603120|imex:IM-9152-508 author score:0.076995584 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:D420B376567B5B44|rigid:6crgYC139KETTdGiMuIYdGylHS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83574 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603132|imex:IM-9152-510 author score:0.042979445 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:71FE9C04BE4BE3DD|rigid:URy4x671dWnEy6PXIhL8daoCwgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83969 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603126|imex:IM-9152-509 author score:0.069682556 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:A513E434BBFD7E32|rigid:4udXGFBllmXj2eoMsSzDWUtndCE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83413 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603138|imex:IM-9152-511 author score:0.024880519 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:E6FE4D64FFC39664|rigid:zA9FSUX3H+V78mhJFg0y+gs7udI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83767 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603144|imex:IM-9152-512 author score:0.015472776 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:1E0BB483A03627B3|rigid:7Wct1R3jencvs9eB/h+TbtLrp50 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83449 uniprotkb:O83282 intact:EBI-1602959|ensemblbacteria:AAC65422 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603150|imex:IM-9152-513 author score:0.005184412 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:53050ECB06E66C22|rigid:sJ3vat7Uabil8z3HBUWL57lkNow false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83449 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603156|imex:IM-9152-514 author score:0.004297743 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:B317B75EB77715E5|rigid:5NUrCeDAt3sATInPByrZ/VNu8e8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83449 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1602959|ensemblbacteria:AAC65422 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83449_trepa(display_long)|uniprotkb:TP_0434(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603162|imex:IM-9152-515 author score:0.000255453 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65422(transcript)|ensemblbacteria:TP_0434(gene)|go:"GO:0042834"(peptidoglycan binding)|interpro:IPR036680 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0434; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:FveDWtibnWUgcQb8nl8HdBfXkIM243276 intact-crc:E2F0D540532C757D|rigid:uy9L8XbzPfwYEVgZMnCmZQQYbZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83792 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1603168|ensemblbacteria:AAC65787 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:y816_trepa(display_long)|uniprotkb:TP_0816(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603171|imex:IM-9152-516 author score:0.329171391 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 refseq:WP_010882260.1|ensemblbacteria:AAC65787(transcript)|ensemblbacteria:TP_0816(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0816; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:6kuxlfmsn+e1Nt+RMF768WTxpeM243276 intact-crc:E73DF09C6910C33B|rigid:B2dmz9Lzc1Rg5INXOfDPqBS2zJM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83792 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1603168|ensemblbacteria:AAC65787 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y816_trepa(display_long)|uniprotkb:TP_0816(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603183|imex:IM-9152-518 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010882260.1|ensemblbacteria:AAC65787(transcript)|ensemblbacteria:TP_0816(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0816; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:6kuxlfmsn+e1Nt+RMF768WTxpeM243276 intact-crc:67997CF52F745915|rigid:NtHJmvOlIzKbUnwjv93NS3O+N/E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83792 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1603168|ensemblbacteria:AAC65787 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y816_trepa(display_long)|uniprotkb:TP_0816(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603177|imex:IM-9152-517 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 refseq:WP_010882260.1|ensemblbacteria:AAC65787(transcript)|ensemblbacteria:TP_0816(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0816; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:6kuxlfmsn+e1Nt+RMF768WTxpeM243276 intact-crc:FCBE0E9C13987D48|rigid:YHUIoNMxLgAcxMBAnFrq5hSIYrk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83792 uniprotkb:O83282 intact:EBI-1603168|ensemblbacteria:AAC65787 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y816_trepa(display_long)|uniprotkb:TP_0816(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603189|imex:IM-9152-519 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882260.1|ensemblbacteria:AAC65787(transcript)|ensemblbacteria:TP_0816(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0816; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6kuxlfmsn+e1Nt+RMF768WTxpeM243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:68C75C4771116225|rigid:zVI237C8/PhkncjeMeCTCi1oqEU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83792 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1603168|ensemblbacteria:AAC65787 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y816_trepa(display_long)|uniprotkb:TP_0816(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603195|imex:IM-9152-520 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010882260.1|ensemblbacteria:AAC65787(transcript)|ensemblbacteria:TP_0816(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0816; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:6kuxlfmsn+e1Nt+RMF768WTxpeM243276 intact-crc:0B706CD5D9CDCBD4|rigid:DzVVYkMI0+L+hyERc1p7/odGR2s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O66075 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1593152|ensemblbacteria:AAC65244 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603201|imex:IM-9152-521 author score:0.328315816 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0255|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 intact-crc:729733A89B3A25A9|rigid:SBKv3VcBzSbD+BWlnTxPYK6Rym8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83563 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603210|imex:IM-9152-522 author score:0.32240642 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0552|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:4934593DF8303A38|rigid:ocrLUPdBEv7S2detXYah79OVPdo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83478 uniprotkb:O83168 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603216|imex:IM-9152-523 author score:0.299343785 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:F62A2885674FAF4E|rigid:sYlPLMHfN2KcfZXRWEEw9oChpfg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83647 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1582557|ensemblbacteria:AAC65615 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:syh_trepa(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0641(locus name)|uniprotkb:hisS(gene name)|psi-mi:hisS(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603228|imex:IM-9152-525 author score:0.288173884 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|ensemblbacteria:AAC65615(transcript)|ensemblbacteria:TP_0641(gene)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|refseq:WP_010882086.1|interpro:IPR041715 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0641|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:G6Um5xNcx3hVPS4/9SW6mZer4V0243276 intact-crc:5C4A45297C8256C8|rigid:hXSz36B/bbUoPDPYYsU1kWs04DI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83962 uniprotkb:O83168 intact:EBI-1592165|ensemblbacteria:AAC26585 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603222|imex:IM-9152-524 author score:0.293727821 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:BB1A5352BC54806F|rigid:Ar/EwYrdlPqa1YJoQcRICYuQI5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83168 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603240|imex:IM-9152-527 author score:0.256201779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:844D3194AF4CC1FD|rigid:5Y1l5AV5WSTgeMWfgGMDSbfa3V0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83986 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603234|imex:IM-9152-526 author score:0.266596548 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:B8805FA9322CE32E|rigid:WBdLuTCq+1LFhO/Wf5rKuCQXo7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83227 uniprotkb:O83168 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603246|imex:IM-9152-528 author score:0.256201779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:C3A31493E2E5D489|rigid:NuDzn4xnw9XnhipKfO3NZpVQAWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:Q08255 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1584220|ensemblbacteria:AAC65647 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603252|imex:IM-9152-529 author score:0.256201779 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 intact-crc:75F0065F05B21E5A|rigid:LoxCzQLVQXa0uN+9CVDhH4Z6kcI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83168 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603258|imex:IM-9152-530 author score:0.236223943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:469E3C4737DFFD07|rigid:bL+d3NGKwRtW33yZ8ZN6ZMDq/AU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O66106 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603264|imex:IM-9152-531 author score:0.236223943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:2A5873DB6CCAE757|rigid:Qc0rNKu6J4umXFXdXx8L5Aior0I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83168 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603270|imex:IM-9152-532 author score:0.231401072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:AC22E90370EE64DB|rigid:JKuRcjs/BZyTYW98QpaxPXVR9o4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O66107 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603276|imex:IM-9152-533 author score:0.226647447 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:49D5CBFF9EAB7C90|rigid:iginc24la9gODYBrV2GB2rOy4dI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83168 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603282|imex:IM-9152-534 author score:0.217348703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:F5CE454FF1486F42|rigid:ZYoM/YbHVd1H/eOJPTx8wzs3wQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83168 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603288|imex:IM-9152-535 author score:0.217348703 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:4DC6387210B6950B|rigid:VT1TRpdSj9EVb+j+fAHRqPLeo0w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83570 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603300|imex:IM-9152-537 author score:0.203923284 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:61F187D258B79EFB|rigid:ZTORTFW3uTtP7/tdYTIYMQxobzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83168 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603294|imex:IM-9152-536 author score:0.212803827 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:CF1953719D4FCEEF|rigid:DCjxhSCwf+Z0VX6qi1rdQg+rZXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83168 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603312|imex:IM-9152-539 author score:0.186997096 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:841AE19D9592AE9D|rigid:RZNOwQCa77Jj6OANdSb6AtHi3/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83311 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603306|imex:IM-9152-538 author score:0.19958755 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 intact-crc:F9B2723ED8B7A830|rigid:Pjasi9vk34Kg8vhXxt0N9Xdddw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83532 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603318|imex:IM-9152-540 author score:0.186997096 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:43BE36ADBD7ACDBE|rigid:e+tmCbSsO64WCv0MWSgGyrlrrRM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83168 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603324|imex:IM-9152-541 author score:0.1750272 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:B5357533AEC51F47|rigid:xiYTOu+t2gpIDu8LpG4w7cA7DBU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83670 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603330|imex:IM-9152-542 author score:0.171173739 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:0510DC56CBE3A07B|rigid:snkKyHBZ1fRHPBZxI7M3A7yHVcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83738 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603336|imex:IM-9152-543 author score:0.163669263 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:D34CFF688569617D|rigid:EpvB+7JUIiEjGi06+GfoPCD7jw0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83709 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603342|imex:IM-9152-544 author score:0.130063072 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:BB6915A0DDC50577|rigid:y0SWwxOeC2SvWlnVs70LS+RBdHE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83168 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603348|imex:IM-9152-545 author score:0.115575455 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:7CD884AE6DAB9BB3|rigid:iJYuIi6RRpr96Fp6W5jWYQpIyWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83168 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603354|imex:IM-9152-546 author score:0.08432325 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:53BB306B5C61F8F1|rigid:i5l94m/5vUJp4JRfScVHQH7suPk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83398 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603360|imex:IM-9152-547 author score:0.082267618 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:F93F96ED6109590E|rigid:vfYi5ymA5DiE86BiIngaR6+pwDk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83982 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603366|imex:IM-9152-548 author score:0.082267618 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:16B8D296C2BFE14F|rigid:X/c6spquZICVE+gTMZFMfZ8pmrU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83099 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603378|imex:IM-9152-550 author score:0.059416948 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:6B35AE8BD2B481E5|rigid:WDDhMdUCT3gysBHNLdWsQ4fHJS4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83531 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603372|imex:IM-9152-549 author score:0.072659232 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:1E9FD2DA83522228|rigid:ROnOLwWuJzqoyBb8woAc1LInAA0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83877 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603384|imex:IM-9152-551 author score:0.025996837 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:D6AF5D381B6AE875|rigid:bBkPXShtdvVUPa0THuLMGkWEgE8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83667 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603390|imex:IM-9152-552 author score:0.021628089 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:85ED17F71201CE02|rigid:O8dR6zp1BfkZbbes5Zc8sBpRDcQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83168 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603402|imex:IM-9152-554 author score:0.012078318 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:AA3AD576E9F103A9|rigid:jQxBOpguOnC5Rr3eApvwEEonP+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83168 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603396|imex:IM-9152-553 author score:0.014546749 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:C3CEEDA0186B211F|rigid:ytiTp9OY6oV7jZ1n0SrU1Gni03g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83168 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1603205|ensemblbacteria:AAC65123 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603414|imex:IM-9152-556 author score:0.000239942 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 intact-crc:1325538AEFE0ED4D|rigid:CGbGccDouSoLd5Q3btRnCz7jAiI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83168 uniprotkb:O83954 intact:EBI-1603205|ensemblbacteria:AAC65123 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y132_trepa(display_long)|uniprotkb:TP_0132(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603408|imex:IM-9152-555 author score:0.004037785 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65123(transcript)|ensemblbacteria:TP_0132(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0132; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pr5QPFtj0Te4xAqPnTArRGdleSI243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:679983531BB4D27C|rigid:osCsxB4j7e7NhSxjib1G0hPhsQ0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83555 uniprotkb:O83282 intact:EBI-1603420|ensemblbacteria:AAC65531|ensemblbacteria:AGN75731 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83555_trepa(display_long)|uniprotkb:TP_0544(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603429|imex:IM-9152-558 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:WP_010881991.1|ensemblbacteria:AAC65531(transcript)|ensemblbacteria:AGN75731(transcript)|ensemblbacteria:TP_0544(gene)|ensemblbacteria:TPANIC_0544(gene)|go:"GO:0003824"(catalytic activity)|interpro:IPR036691 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0544; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Lvn2H2+qs7Z4P4QPuOIkcM97um0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:AD0FD9270791BD35|rigid:5izVXb/OSU38IWqdtAHlIpGxRVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83555 uniprotkb:P21992 intact:EBI-1603420|ensemblbacteria:AAC65531|ensemblbacteria:AGN75731 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:o83555_trepa(display_long)|uniprotkb:TP_0544(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603423|imex:IM-9152-557 author score:0.3271204 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:WP_010881991.1|ensemblbacteria:AAC65531(transcript)|ensemblbacteria:AGN75731(transcript)|ensemblbacteria:TP_0544(gene)|ensemblbacteria:TPANIC_0544(gene)|go:"GO:0003824"(catalytic activity)|interpro:IPR036691 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0544; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Lvn2H2+qs7Z4P4QPuOIkcM97um0243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:7CBF8F727D81115C|rigid:lqNe6TZxa1d8bDV2Pmavfo7SZD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83555 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1603420|ensemblbacteria:AAC65531|ensemblbacteria:AGN75731 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83555_trepa(display_long)|uniprotkb:TP_0544(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603435|imex:IM-9152-559 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:WP_010881991.1|ensemblbacteria:AAC65531(transcript)|ensemblbacteria:AGN75731(transcript)|ensemblbacteria:TP_0544(gene)|ensemblbacteria:TPANIC_0544(gene)|go:"GO:0003824"(catalytic activity)|interpro:IPR036691 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0544; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Lvn2H2+qs7Z4P4QPuOIkcM97um0243276 intact-crc:CF9209B512D13CD1|rigid:Q6rJrBSB+EKHwyd5clNqiZRP/iE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83802 uniprotkb:O83312 intact:EBI-1603445|ensemblbacteria:AAC65796 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:trua_trepa(display_long)|uniprotkb:truA(gene name)|psi-mi:truA(display_short)|uniprotkb:hisT(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:TP_0830(locus name)|uniprotkb:"tRNA pseudouridine(38-40) synthase"(gene name synonym) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603441|imex:IM-9152-560 author score:0.325184226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020097|interpro:IPR020095|ensemblbacteria:AAC65796(transcript)|ensemblbacteria:TP_0830(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|refseq:WP_010882274.1|interpro:IPR020094 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0830; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:U0UeYHAGSSkkQTkxV1hSf1uiC/Y243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:9FD24A65D4ECCCF3|rigid:btgLKY+INdTNvhfiii4aaPYhQkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83802 uniprotkb:O83877 intact:EBI-1603445|ensemblbacteria:AAC65796 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:trua_trepa(display_long)|uniprotkb:truA(gene name)|psi-mi:truA(display_short)|uniprotkb:hisT(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:TP_0830(locus name)|uniprotkb:"tRNA pseudouridine(38-40) synthase"(gene name synonym) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603451|imex:IM-9152-561 author score:0.165413283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020097|interpro:IPR020095|ensemblbacteria:AAC65796(transcript)|ensemblbacteria:TP_0830(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|refseq:WP_010882274.1|interpro:IPR020094 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0830; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:U0UeYHAGSSkkQTkxV1hSf1uiC/Y243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:A00222E196882CFA|rigid:bi/60YnsIwPSyIK16nOt/synXJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83802 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1603445|ensemblbacteria:AAC65796 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:trua_trepa(display_long)|uniprotkb:truA(gene name)|psi-mi:truA(display_short)|uniprotkb:hisT(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:TP_0830(locus name)|uniprotkb:"tRNA pseudouridine(38-40) synthase"(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603457|imex:IM-9152-562 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR020103|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020097|interpro:IPR020095|ensemblbacteria:AAC65796(transcript)|ensemblbacteria:TP_0830(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|refseq:WP_010882274.1|interpro:IPR020094 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0830; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:U0UeYHAGSSkkQTkxV1hSf1uiC/Y243276 intact-crc:D841136CDF2A2273|rigid:FMIETClBthBz4iQeBpDvWwsrg7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83802 uniprotkb:O83958 intact:EBI-1603445|ensemblbacteria:AAC65796 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:trua_trepa(display_long)|uniprotkb:truA(gene name)|psi-mi:truA(display_short)|uniprotkb:hisT(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:TP_0830(locus name)|uniprotkb:"tRNA pseudouridine(38-40) synthase"(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603463|imex:IM-9152-563 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020103|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020097|interpro:IPR020095|ensemblbacteria:AAC65796(transcript)|ensemblbacteria:TP_0830(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|refseq:WP_010882274.1|interpro:IPR020094 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0830; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:U0UeYHAGSSkkQTkxV1hSf1uiC/Y243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:28474C8183FA08DF|rigid:paTWJFEB/HUbZt9MmYcma+YjULE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83957 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1589703|ensemblbacteria:AAC65948|ensemblbacteria:AGN76156 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83957_trepa(display_long)|uniprotkb:TP_0992(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603475|imex:IM-9152-565 author score:0.165413283 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65948(transcript)|ensemblbacteria:AGN76156(transcript)|ensemblbacteria:TP_0992(gene)|ensemblbacteria:TPANIC_0992(gene)|refseq:WP_010882436.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0992; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:EIrFAyXg8Dt2Z/CS5ZukQWliPWI243276 intact-crc:636CB8CB01F6E072|rigid:zhaaf691dvesROOfyv/lJO3SpA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83957 uniprotkb:O83312 intact:EBI-1589703|ensemblbacteria:AAC65948|ensemblbacteria:AGN76156 intact:EBI-1581856|ensemblbacteria:AAC65270 psi-mi:o83957_trepa(display_long)|uniprotkb:TP_0992(locus name) psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603469|imex:IM-9152-564 author score:0.325184226 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65948(transcript)|ensemblbacteria:AGN76156(transcript)|ensemblbacteria:TP_0992(gene)|ensemblbacteria:TPANIC_0992(gene)|refseq:WP_010882436.1 interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0992; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:EIrFAyXg8Dt2Z/CS5ZukQWliPWI243276 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 intact-crc:8B5778A0C6460070|rigid:fZxFbf4aYoQHoriM/+9t0Ef1fTQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83957 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1589703|ensemblbacteria:AAC65948|ensemblbacteria:AGN76156 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83957_trepa(display_long)|uniprotkb:TP_0992(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603481|imex:IM-9152-566 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65948(transcript)|ensemblbacteria:AGN76156(transcript)|ensemblbacteria:TP_0992(gene)|ensemblbacteria:TPANIC_0992(gene)|refseq:WP_010882436.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0992; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:EIrFAyXg8Dt2Z/CS5ZukQWliPWI243276 intact-crc:A65D186F7E85F2A8|rigid:m5/RSTW0HuM6tBeZ2zL9wJcVRxo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83957 uniprotkb:O83282 intact:EBI-1589703|ensemblbacteria:AAC65948|ensemblbacteria:AGN76156 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83957_trepa(display_long)|uniprotkb:TP_0992(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603487|imex:IM-9152-567 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65948(transcript)|ensemblbacteria:AGN76156(transcript)|ensemblbacteria:TP_0992(gene)|ensemblbacteria:TPANIC_0992(gene)|refseq:WP_010882436.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0992; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:EIrFAyXg8Dt2Z/CS5ZukQWliPWI243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8A7D8718CD518B89|rigid:H1zo4ba2p/Yr1YXknCS+odCOONg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83549 uniprotkb:O83927 intact:EBI-1603497|ensemblbacteria:AAC65523 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:pgk_trepa(display_long)|uniprotkb:pgk(gene name)|psi-mi:pgk(display_short)|uniprotkb:TP_0538(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603493|imex:IM-9152-568 author score:0.325075995 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|ensemblbacteria:AAC65523(transcript)|ensemblbacteria:TP_0538(gene)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process)|interpro:IPR036043 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0538; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:tsskESZyq2/69sZsVkXBG+7P+VM243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:E38ED4F8D36AE5D5|rigid:a1FoBvLfK8o2Lvz4NuUO0qOxcNI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21992 uniprotkb:O83828 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 intact:EBI-1586932|ensemblbacteria:AAC65828 psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:y856_trepa(display_long)|uniprotkb:TP_0856(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603509|imex:IM-9152-570 author score:0.313481504 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65828(transcript)|ensemblbacteria:TP_0856(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0856; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 rogid:yWQHb9hzPMZ1HBvQbPI4IcndhHY243276 intact-crc:D78CBD2888174434|rigid:h0R7fRVeLK5IB98MX4j0MM1qs9U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83828 uniprotkb:O83099 intact:EBI-1586932|ensemblbacteria:AAC65828 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:y856_trepa(display_long)|uniprotkb:TP_0856(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603503|imex:IM-9152-569 author score:0.319304401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65828(transcript)|ensemblbacteria:TP_0856(gene) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0856; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yWQHb9hzPMZ1HBvQbPI4IcndhHY243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:B066FCEAAEFA9A88|rigid:p5zY9SFk5JUYjzSwUZroLPgVlkk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83828 uniprotkb:O83574 intact:EBI-1586932|ensemblbacteria:AAC65828 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y856_trepa(display_long)|uniprotkb:TP_0856(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603515|imex:IM-9152-571 author score:0.238520594 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65828(transcript)|ensemblbacteria:TP_0856(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0856; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yWQHb9hzPMZ1HBvQbPI4IcndhHY243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:D328C434D1B5C46D|rigid:scnCzOX7E/3RWLCCleCnIZj4pWk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83828 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1586932|ensemblbacteria:AAC65828 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y856_trepa(display_long)|uniprotkb:TP_0856(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603521|imex:IM-9152-572 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR005362(Protein of unknown function UPF0164)|ensemblbacteria:AAC65828(transcript)|ensemblbacteria:TP_0856(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0856; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:yWQHb9hzPMZ1HBvQbPI4IcndhHY243276 intact-crc:AA0273C39EDDDCA5|rigid:33bIdvIThUtX14ngRwSDPA+6vtg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83312 uniprotkb:O83224 intact:EBI-1581856|ensemblbacteria:AAC65270 intact:EBI-1603527|ensemblbacteria:AAC65179 psi-mi:o83312_trepa(display_long)|uniprotkb:TP_0288(locus name) psi-mi:rl22_trepa(display_long)|uniprotkb:rplV(gene name)|psi-mi:rplV(display_short)|uniprotkb:TP_0194(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603531|imex:IM-9152-573 author score:0.311588675 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029044|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|ensemblbacteria:AAC65270(transcript)|ensemblbacteria:TP_0288(gene) interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR018260|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|refseq:WP_010881641.1|ensemblbacteria:AAC65179(transcript)|ensemblbacteria:TP_0194(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036394 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0194; PREY protein TP_0288|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xRUn7yBGdTH+SWkecunvKLHnsNQ243276 rogid:Aas7yAAfCDcITR8/wilyqGZQTCQ243276 intact-crc:AB03BF3FD9989F5B|rigid:MyFD2emDfQ42Jv137zEHz6+1IEc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83224 uniprotkb:O83667 intact:EBI-1603527|ensemblbacteria:AAC65179 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rl22_trepa(display_long)|uniprotkb:rplV(gene name)|psi-mi:rplV(display_short)|uniprotkb:TP_0194(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603537|imex:IM-9152-574 author score:0.133587829 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR018260|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|refseq:WP_010881641.1|ensemblbacteria:AAC65179(transcript)|ensemblbacteria:TP_0194(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036394 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0194; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Aas7yAAfCDcITR8/wilyqGZQTCQ243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:B61C732EB8BDFF5A|rigid:g3IS8sfNqpSDW3a32xTO6pKHUrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83224 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1603527|ensemblbacteria:AAC65179 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rl22_trepa(display_long)|uniprotkb:rplV(gene name)|psi-mi:rplV(display_short)|uniprotkb:TP_0194(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603543|imex:IM-9152-575 author score:0.078572954 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR018260|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|refseq:WP_010881641.1|ensemblbacteria:AAC65179(transcript)|ensemblbacteria:TP_0194(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036394 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0194; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:Aas7yAAfCDcITR8/wilyqGZQTCQ243276 intact-crc:72E536D15D234235|rigid:Zn0jAsb/o02SG7b3HXx5LBB/Qwo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83224 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1603527|ensemblbacteria:AAC65179 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl22_trepa(display_long)|uniprotkb:rplV(gene name)|psi-mi:rplV(display_short)|uniprotkb:TP_0194(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603549|imex:IM-9152-576 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR018260|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|refseq:WP_010881641.1|ensemblbacteria:AAC65179(transcript)|ensemblbacteria:TP_0194(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036394 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0194; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Aas7yAAfCDcITR8/wilyqGZQTCQ243276 intact-crc:6BA46D855DF4F212|rigid:MKtmMGa0h3Zzt0Hp8Ci0NFzh/oM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83224 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1603527|ensemblbacteria:AAC65179 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rl22_trepa(display_long)|uniprotkb:rplV(gene name)|psi-mi:rplV(display_short)|uniprotkb:TP_0194(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603555|imex:IM-9152-577 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR018260|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|refseq:WP_010881641.1|ensemblbacteria:AAC65179(transcript)|ensemblbacteria:TP_0194(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036394 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0194; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Aas7yAAfCDcITR8/wilyqGZQTCQ243276 intact-crc:0E964512D3FB3A00|rigid:mHKMJUVuzkFOCm7CxvXZCCkVQS8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83888 uniprotkb:O83927 intact:EBI-1603565|ensemblbacteria:AAC65874|ensemblbacteria:AGN76085 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83888_trepa(display_long)|uniprotkb:TP_0918(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603561|imex:IM-9152-578 author score:0.31148288 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882361.1|ensemblbacteria:AAC65874(transcript)|ensemblbacteria:AGN76085(transcript)|ensemblbacteria:TP_0918(gene)|ensemblbacteria:TPANIC_0918(gene) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0918; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ny+BnXgLafiabdbwjwWjVX6fUmo243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:C8ED57CA5D904459|rigid:C9qkVRQ0vbUnKAmLnWfH2VVOFaw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83888 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1603565|ensemblbacteria:AAC65874|ensemblbacteria:AGN76085 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83888_trepa(display_long)|uniprotkb:TP_0918(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603570|imex:IM-9152-579 author score:0.238359213 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010882361.1|ensemblbacteria:AAC65874(transcript)|ensemblbacteria:AGN76085(transcript)|ensemblbacteria:TP_0918(gene)|ensemblbacteria:TPANIC_0918(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0918; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:ny+BnXgLafiabdbwjwWjVX6fUmo243276 intact-crc:CC090087A9162808|rigid:ny33Q9Jgz0RS+2E6E8wpM1NcY6U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83969 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603576|imex:IM-9152-580 author score:0.302115441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:23975C5CABA692FF|rigid:MAc+cZn4jRfTWSifM+9sD/gjtCM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83308 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1586129|ensemblbacteria:AAC65280 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603582|imex:IM-9152-581 author score:0.128516062 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 intact-crc:F539D5173391C3C1|rigid:MYPmcFS0G3aQOStDa8LURIf2pbU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83767 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603588|imex:IM-9152-582 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:B365DC7D59BFBB3C|rigid:TYYPfYBkH7ZiryA9STCROfosRVQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83745 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603594|imex:IM-9152-583 author score:0.06996641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:62A5872C986A58BF|rigid:EUPUQGeYrwfnfL5aNEFgmkM2X4Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83282 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603600|imex:IM-9152-584 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:280C7DEDEEE6B5FC|rigid:n4wEbpQvdImosd7pbMnjOs0gubc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83308 uniprotkb:O83954 intact:EBI-1586129|ensemblbacteria:AAC65280 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603606|imex:IM-9152-930 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F2C1C1F8394C1937|rigid:Fi2RJV+im2HJZrC5y8DTcXtivWM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83308 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586129|ensemblbacteria:AAC65280 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y284_trepa(display_long)|uniprotkb:TP_0284(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603612|imex:IM-9152-586 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65280(transcript)|ensemblbacteria:TP_0284(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0284; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:vL4KEvsNJyiYM6qUq0tXOIC2vE4243276 intact-crc:87D3B26DDB81A8F3|rigid:V8736fO9ij8wlWpC6xuYcoPaDCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83576 uniprotkb:O83927 intact:EBI-1603618|ensemblbacteria:AAC65548|ensemblbacteria:AGN75752 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83576_trepa(display_long)|uniprotkb:TP_0565(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603621|imex:IM-9152-587 author score:0.298207024 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007407(Protein of unknown function DUF459)|ensemblbacteria:AAC65548(transcript)|ensemblbacteria:AGN75752(transcript)|ensemblbacteria:TP_0565(gene)|ensemblbacteria:TPANIC_0565(gene)|interpro:IPR036514 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0565; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1qYKaW6S0Z05UrGLco7Ike39O9g243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:644B49732833D4A2|rigid:CKKeo+y069qoaBxAtMy194VodVI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83576 uniprotkb:O83954 intact:EBI-1603618|ensemblbacteria:AAC65548|ensemblbacteria:AGN75752 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83576_trepa(display_long)|uniprotkb:TP_0565(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603627|imex:IM-9152-588 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007407(Protein of unknown function DUF459)|ensemblbacteria:AAC65548(transcript)|ensemblbacteria:AGN75752(transcript)|ensemblbacteria:TP_0565(gene)|ensemblbacteria:TPANIC_0565(gene)|interpro:IPR036514 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0565; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1qYKaW6S0Z05UrGLco7Ike39O9g243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:B498E6C3681CCBCA|rigid:4F4zH8bC/yk/88qd3DZ6rSo5Kao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83898 uniprotkb:O83927 intact:EBI-1585589|ensemblbacteria:AAC65887 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:y928_trepa(display_long)|uniprotkb:TP_0928(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603639|imex:IM-9152-590 author score:0.298207024 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65887(transcript)|ensemblbacteria:TP_0928(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882371.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0928; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pk6pOPdwzaF0NT5fTg+KJYTFZLg243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:A509BD7281BAA534|rigid:Ir9flLcTQJsBhtZDHxvoFhme23M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83576 uniprotkb:O83958 intact:EBI-1603618|ensemblbacteria:AAC65548|ensemblbacteria:AGN75752 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83576_trepa(display_long)|uniprotkb:TP_0565(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603633|imex:IM-9152-589 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007407(Protein of unknown function DUF459)|ensemblbacteria:AAC65548(transcript)|ensemblbacteria:AGN75752(transcript)|ensemblbacteria:TP_0565(gene)|ensemblbacteria:TPANIC_0565(gene)|interpro:IPR036514 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0565; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1qYKaW6S0Z05UrGLco7Ike39O9g243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BAEB37BA58822BD1|rigid:Ij2A8qZ0HMMJQF+Rn96rqzhhQes false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83898 uniprotkb:O83958 intact:EBI-1585589|ensemblbacteria:AAC65887 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y928_trepa(display_long)|uniprotkb:TP_0928(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603651|imex:IM-9152-592 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65887(transcript)|ensemblbacteria:TP_0928(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882371.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0928; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pk6pOPdwzaF0NT5fTg+KJYTFZLg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7BA9C3BBF10B5A47|rigid:5uo4wOycRQ4q8Pnxmbhi/tcmaCg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83902 uniprotkb:O83667 intact:EBI-1595369|ensemblbacteria:AAC65890 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y932_trepa(display_long)|uniprotkb:TP_0932(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603657|imex:IM-9152-593 author score:0.293830159 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65890(transcript)|ensemblbacteria:TP_0932(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0932|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZBtgIlu03HjMbIt9NBFIw64lVo0243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C88B83F74A080FE5|rigid:UFNHz4qGVnXTfe9eVOr+/rewnBE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83898 uniprotkb:O83745 intact:EBI-1585589|ensemblbacteria:AAC65887 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y928_trepa(display_long)|uniprotkb:TP_0928(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603645|imex:IM-9152-591 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65887(transcript)|ensemblbacteria:TP_0928(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882371.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0928; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pk6pOPdwzaF0NT5fTg+KJYTFZLg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:71869CB74729D58E|rigid:sDyjOL93hF9vyKdXtLsZW978N3k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83218 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1584091|ensemblbacteria:AAC65173 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rs10_trepa(display_long)|uniprotkb:rpsJ(gene name)|psi-mi:rpsJ(display_short)|uniprotkb:TP_0188(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603663|imex:IM-9152-594 author score:0.288275077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001848(Ribosomal protein S10)|interpro:IPR018268|ensemblbacteria:AAC65173(transcript)|ensemblbacteria:TP_0188(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010881635.1|interpro:IPR027486|interpro:IPR036838 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0188|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:4GmqHSYQd4rzQjuJFNAXK+3CXqw243276 intact-crc:FEEDC15301CE17E5|rigid:iPMZPZHrGbl0hlDeLHK7K9Z4p5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83378 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1601823|ensemblbacteria:AAC65354 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603669|imex:IM-9152-595 author score:0.288275077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0359|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 intact-crc:CAD510807B0EF01A|rigid:kZW+zhMNE23P//NHEk1fyiDOrA4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83781 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1590915|ensemblbacteria:AAC65775|ensemblbacteria:AGN75975 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83781_trepa(display_long)|uniprotkb:TP_0803(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603675|imex:IM-9152-596 author score:0.288275077 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|ensemblbacteria:AAC65775(transcript)|ensemblbacteria:AGN75975(transcript)|ensemblbacteria:TP_0803(gene)|ensemblbacteria:TPANIC_0803(gene)|refseq:WP_010882248.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0803|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:Kmxg99Mc5m6f9Vs8JorBwbay0og243276 intact-crc:2CAD4620483F0626|rigid:hy4IRn5XgygaszLdQiOxFHZV4Xk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83526 uniprotkb:O83667 intact:EBI-1592146|ensemblbacteria:AAC65501|ensemblbacteria:AGN75702 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83526_trepa(display_long)|uniprotkb:TP_0513(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603681|imex:IM-9152-597 author score:0.277354704 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|ensemblbacteria:AAC65501(transcript)|ensemblbacteria:AGN75702(transcript)|ensemblbacteria:TP_0513(gene)|ensemblbacteria:TPANIC_0513(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|refseq:WP_010881962.1|interpro:IPR036291|interpro:IPR036721 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0513|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a4ai6430LAmmKePJdR/ZjwQF/H0243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:4C026C5FF70AABA2|rigid:6C3eZiAVmOLI+BzGMTQIs/79oMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83158 uniprotkb:O83667 intact:EBI-1198536|intact:EBI-1586535|ensemblbacteria:AAC65111 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y121_trepa(display_long)|uniprotkb:TP_0121(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603693|imex:IM-9152-599 author score:0.261461011 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR003739(Protein of unknown function DUF160)|ensemblbacteria:AAC65111(transcript)|ensemblbacteria:TP_0121(gene)|go:"GO:0016853"(isomerase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007197(Radical SAM) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0121|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cST7wX3tQsmlfOf9UCUb+Egqe1w243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:A4C39CCA6ECB911E|rigid:OHCiaYsN2+X+vy28aBQiucAx9Rs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83666 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198601|intact:EBI-1582187|ensemblbacteria:AAC65634|ensemblbacteria:AGN75838 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83666_trepa(display_long)|uniprotkb:TP_0660(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603687|imex:IM-9152-598 author score:0.277354704 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR002371(Flagellar hook-associated protein)|interpro:IPR010810(Flagellin hook IN)|refseq:WP_010882105.1|ensemblbacteria:AAC65634(transcript)|ensemblbacteria:AGN75838(transcript)|ensemblbacteria:TP_0660(gene)|ensemblbacteria:TPANIC_0660(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009424"(bacterial-type flagellum hook)|go:"GO:0044780"(bacterial-type flagellum assembly) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0660|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:6zvD4gAWlTZx/E9BY9UgJY469C8243276 intact-crc:A7106E26C63F04F1|rigid:cfHenFulivI5XrPuIty3Z5tcKeA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83373 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603699|imex:IM-9152-600 author score:0.256295787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:7B54D506C7CE99CF|rigid:0DCf8RMFRBu8Hh9XrcaXbfrjynQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83723 uniprotkb:O83667 intact:EBI-1587106|ensemblbacteria:AAC65710 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:nadd_trepa(display_long)|uniprotkb:nadD(gene name)|psi-mi:nadD(display_short)|uniprotkb:"Deamido-NAD(+) pyrophosphorylase"(gene name synonym)|uniprotkb:"Deamido-NAD(+) diphosphorylase"(gene name synonym)|uniprotkb:Nicotinate mononucleotide adenylyltransferase(gene name synonym)|uniprotkb:TP_0741(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603705|imex:IM-9152-601 author score:0.256295787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|ensemblbacteria:AAC65710(transcript)|ensemblbacteria:TP_0741(gene)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0009435"(NAD biosynthetic process)|refseq:WP_010882186.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0741|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:uTODxmb3jN3M8XSNj/3MSI3h4lw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:12338EC0EB028883|rigid:wZsnwcp/j3CjN2NTlArvnz9GA0k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83310 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1588258|ensemblbacteria:AAC65268 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603711|imex:IM-9152-602 author score:0.251197896 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 intact-crc:57AD6F150CD73F90|rigid:CiyCWiSAdNGuQ65acgHKmy5IEQw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83634 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603717|imex:IM-9152-603 author score:0.236312949 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:DF867CF7EB7AD074|rigid:crBZuTi66pEIOgRSB1pilDwBUOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08255 uniprotkb:O83667 intact:EBI-1584220|ensemblbacteria:AAC65647 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603723|imex:IM-9152-604 author score:0.22204847 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:F28B13EB406AA9C5|rigid:Sz93A808IyQj+32gyJgBPRMsyP0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83068 uniprotkb:O83667 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603729|imex:IM-9152-605 author score:0.217432622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:D3B7B8993BF12B11|rigid:dApQ+F0rV59OgB1pJFF/Nuwdd5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83275 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603747|imex:IM-9152-608 author score:0.199666361 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 intact-crc:9893328027653755|rigid:DtJiNMI9hohv9j492E+8tETin7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O66106 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603741|imex:IM-9152-607 author score:0.204003371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:8E161A4ECF85621D|rigid:hz7x7Xf0vBo2u+QnEAmrAWd0LYA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83542 uniprotkb:O83667 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603735|imex:IM-9152-606 author score:0.204003371 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:92E3E9FFFB156D0A|rigid:imI+mJGU1kaA6g9tbwVPMDHVyik false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83667 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603759|imex:IM-9152-610 author score:0.19539892 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:7951CF19FB4AEB91|rigid:b8wG6NSk30Hgj4Cgl1K7TZ7yzZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83098 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603753|imex:IM-9152-609 author score:0.19539892 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:FEEA39B578822554|rigid:ouk723I3jsZG0E0ag8/f/leEoLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83667 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603765|imex:IM-9152-611 author score:0.187072097 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:A265280CB3989566|rigid:v9LnlE0UVpYZzfsOpWdMSZ77sH0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83627 uniprotkb:O83667 intact:EBI-1584236|ensemblbacteria:AAC65601 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603771|imex:IM-9152-612 author score:0.183012279 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:FEF75FA477C8392E|rigid:elx0S2cMHuMKYpdfbc3crR25Z+U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83667 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603777|imex:IM-9152-613 author score:0.179021165 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:AD6562BD991DB587|rigid:8Id6Uzgq+Td7aGmwWULvmXdoj1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83570 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1585774|ensemblbacteria:AAC26563 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:thii_trepa(display_long)|uniprotkb:TP_0559(locus name)|uniprotkb:thiI(gene name)|psi-mi:thiI(display_short)|uniprotkb:tRNA 4-thiouridine synthase(gene name synonym)|uniprotkb:Sulfur carrier protein ThiS sulfurtransferase(gene name synonym)|uniprotkb:Thiamine biosynthesis protein ThiI(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603783|imex:IM-9152-614 author score:0.175098434 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR003720(Thiamine biosynthesis protein)|interpro:IPR020536|interpro:IPR004114(THUMP)|ensemblbacteria:AAC26563(transcript)|ensemblbacteria:TP_0559(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004810"(tRNA adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|refseq:WP_010882006.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0559|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:nRjNMdXYUcorb1xHhmN09rMlxZ0243276 intact-crc:EEE63E276D87DFB8|rigid:i1iS84zLWePuAEaS3WaP2G8/A8A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83667 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603789|imex:IM-9152-615 author score:0.17124373 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:73A5F9251ABB0845|rigid:7p2uepOw0VIQwplixTJdjJ0BpdQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83752 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603801|imex:IM-9152-617 author score:0.160083669 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:9C8D85FF9E06D72F|rigid:hD435JV+uwYYybhkEV/zlppRvYw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83667 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603795|imex:IM-9152-616 author score:0.160083669 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:D86356296E678FBC|rigid:+qod8GjKjC7n0nfRLOw8WCRa1Q8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83667 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603807|imex:IM-9152-618 author score:0.146128346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:11CC9C76D44954AD|rigid:CH66ZVlIkdeIF/NfNpTVRddG+9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83738 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603813|imex:IM-9152-619 author score:0.139537035 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:4BA14AF6ED791A4A|rigid:b+tvRvHXfY2YJgmNOg1jJTw7jfM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83667 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603819|imex:IM-9152-620 author score:0.110232807 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:9E7A8BBA199B34D6|rigid:d8eCZWo+Y+UB8mI8QhbHAGVszwk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83463 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582872|ensemblbacteria:AAC65437 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603825|imex:IM-9152-621 author score:0.09770598 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 intact-crc:6569E8B89D3FB10E|rigid:IXEU/pzEQsNJ3Royrbyw8ffbvYo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83398 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603837|imex:IM-9152-623 author score:0.06914535 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:92E7296C9E5E01F2|rigid:2U3ocH3QfYdQfcX5owJY1WWPeQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83667 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603831|imex:IM-9152-622 author score:0.070898425 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:573E2CD119958EDE|rigid:uUFnN3UokzUL9qn8Q7W1HGcRt4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83982 uniprotkb:O83667 intact:EBI-1582649|ensemblbacteria:AAC65969 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603843|imex:IM-9152-624 author score:0.06914535 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:ECA360F94CCAF4A1|rigid:HEPTNUPC5LgrC014Lsguh11TdaA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83531 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603849|imex:IM-9152-625 author score:0.060967754 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 intact-crc:3B55FA3ECC9CFC3C|rigid:FKgKjjbcWga2cme/25ctEP3OXw8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:P21992 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603855|imex:IM-9152-626 author score:0.048484722 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:2D92F741CDC38601|rigid:b4CocJIJi2kb+zikcUJ8PWOL/Zs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83667 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603861|imex:IM-9152-627 author score:0.019472382 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:67576A6BECF96DD0|rigid:GF0F1CYMzgj2iU/ruu6WXIts3Ac false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83667 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603867|imex:IM-9152-628 author score:0.017988664 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:55B83C4156C58803|rigid:gMIk0NHryYKSOT0C1ixMO8jw0v4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83667 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603873|imex:IM-9152-629 author score:0.004039769 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:63F435E3957E914F|rigid:dFRKE/Q6aAckM+yZOQXNJZJlTGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83954 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603879|imex:IM-9152-630 author score:0.003348205 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:A893C08D46998583|rigid:UXjNchQVv7U0rQb/SagYIrfQINA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83667 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603885|imex:IM-9152-631 author score:0.000198835 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0661; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:11EAA7C6FAF4355C|rigid:gVbadx/6UR/Ur7nvJDzwFxWwlj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83085 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603895|imex:IM-9152-632 author score:0.292705589 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 intact-crc:B50B8F8DADDE2012|rigid:/EOEHWvg1c0BekwS3KQRDN8VCsY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83085 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603901|imex:IM-9152-633 author score:0.135698184 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 intact-crc:C76E5126B66FF6DF|rigid:2znfewn/F5SPtdpBGLgF4hpX0dE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83085 uniprotkb:O83667 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603907|imex:IM-9152-634 author score:0.126501055 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:083E58F4CDBE6B05|rigid:NaDCcblHOOuGP5XQoDQ18PvQvGY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83085 uniprotkb:O83282 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603913|imex:IM-9152-635 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:BF696C4EA1A3AC03|rigid:idBLLpCHx+8zQtn2DgxIR5zaPBk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83085 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603919|imex:IM-9152-636 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 intact-crc:6D704FE127BDD9BA|rigid:cjcNi6KLe0WJbR4zLX1j/jIE/rc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83085 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1603891|ensemblbacteria:AAC65039|ensemblbacteria:AGN75265|uniprotkb:R9UUU2 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:addl_trepa(display_long)|uniprotkb:add(gene name)|psi-mi:add(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)|uniprotkb:TPANIC_0045(orf name)|uniprotkb:TP_0045(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603925|imex:IM-9152-637 author score:0.002235868 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR032466|refseq:WP_010881494.1|ensemblbacteria:AAC65039(transcript)|ensemblbacteria:AGN75265(transcript)|ensemblbacteria:TP_0045(gene)|ensemblbacteria:TPANIC_0045(gene)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0045; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:sxdFHjivZrWBTSf6m8kZVSh1a8c243276 intact-crc:4E5BB910AE0F744A|rigid:S8EWdEvMzUh5AHenFURRE+rcF30 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83207 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1589433|ensemblbacteria:AAC65167 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y177_trepa(display_long)|uniprotkb:TP_0177(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603931|imex:IM-9152-638 author score:0.280999622 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR002826(Protein of unknown function DUF115)|ensemblbacteria:AAC65167(transcript)|ensemblbacteria:TP_0177(gene)|refseq:WP_010881624.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0177|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:3shVxHP2/lmq91hsOLVmAvH9Zuc243276 intact-crc:FCDB2F9FAF0F9167|rigid:sNi2lYBIRkL7OTxCi7Yu6FgwCjE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83563 uniprotkb:O83135 intact:EBI-1598364|ensemblbacteria:AAC65538 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603946|imex:IM-9152-640 author score:0.270250206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0552|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:8D2F18C62145E0F6|rigid:JQz9ePzSWcALchG1I2Gu+fWvoPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83117 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1603937|ensemblbacteria:AAC65073|ensemblbacteria:AGN75297 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83117_trepa(display_long)|uniprotkb:TP_0078(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603940|imex:IM-9152-639 author score:0.275592444 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR000653(DegT/DnrJ/EryC1/StrS aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_010881527.1|ensemblbacteria:AAC65073(transcript)|ensemblbacteria:AGN75297(transcript)|ensemblbacteria:TP_0078(gene)|ensemblbacteria:TPANIC_0078(gene)|go:"GO:0003824"(catalytic activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0078|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:dgs5VaBoQFLr25HA4x1ZHP0Mvlw243276 intact-crc:81DB0A6BB78AC18F|rigid:oNP/pzHKxao5tfREnp2NjruoY6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83427 uniprotkb:O83135 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603952|imex:IM-9152-641 author score:0.264973645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0412|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:557AE9FBAD60AC1C|rigid:SP3Ac6KE9tppyuukcOoZoQnLDrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83732 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198997|intact:EBI-1585254|ensemblbacteria:AAC65720 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y751_trepa(display_long)|uniprotkb:TP_0751(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603958|imex:IM-9152-642 author score:0.249544441 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 rcsb pdb:5JK2|refseq:WP_010882196.1|ensemblbacteria:AAC65720(transcript)|ensemblbacteria:TP_0751(gene)|interpro:IPR041037 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0751|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:G+1T7UF78J7P7nJbIY3NE+CmLDs243276 intact-crc:FB63F871686EAFF7|rigid:mVQEIkWjqpNeoxQcE3OPSEBRiFQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83962 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1592165|ensemblbacteria:AAC26585 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603964|imex:IM-9152-643 author score:0.244536684 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 intact-crc:E07B38FDB2F1C259|rigid:PQqsEL4fZ0QdFV7Oq68cG+GO2Js false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83135 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603970|imex:IM-9152-644 author score:0.243979903 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:2CEC033850445A4B|rigid:mCLquYbJfUjZ/J/wL5m8Rl3PT+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83310 uniprotkb:O83135 intact:EBI-1588258|ensemblbacteria:AAC65268 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603976|imex:IM-9152-645 author score:0.239597336 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:EF185AE6DD75573F|rigid:v+Y5QXhWAma0GHKObs9Yb7+pLyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83702 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603982|imex:IM-9152-646 author score:0.225193063 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 intact-crc:B0D331975E48F566|rigid:MrfDY1ZB21f8oXEslQKUTCuFELU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08255 uniprotkb:O83135 intact:EBI-1584220|ensemblbacteria:AAC65647 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:mglb_trepa(display_long)|uniprotkb:mglB(gene name)|psi-mi:mglB(display_short)|uniprotkb:tpp38(gene name synonym)|uniprotkb:TP_0684(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603988|imex:IM-9152-647 author score:0.211413992 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR025997|interpro:IPR040740|rcsb pdb:5JX2|ensemblbacteria:AAC65647(transcript)|ensemblbacteria:TP_0684(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|rcsb pdb:6BGC|rcsb pdb:6BGD|interpro:IPR028082|refseq:WP_010882129.1 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0684|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:KI0XTuhJgwU/T5rrMC++1aE7eKI243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:0CA81003FEE96B27|rigid:iv8PkTqNRNXuSmoq8a6ugb5sH4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83752 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1603994|imex:IM-9152-648 author score:0.197783288 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:6C9077AF68F5C470|rigid:1JCLbXubkTfC8jVSfDUr8ulYuKQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83532 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604000|imex:IM-9152-649 author score:0.196276289 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:8D8704766FCB5264|rigid:HUTR1mAkwIm5jLx4XFOB9cVkPfk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66106 uniprotkb:O83135 intact:EBI-1583195|ensemblbacteria:AAC65903 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604006|imex:IM-9152-650 author score:0.194017585 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:55B94DD42517F72C|rigid:3ks/3X/6rBH4qWRc0dpyOamWV6g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83135 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604018|imex:IM-9152-652 author score:0.185736038 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:E66557E77AF18FA5|rigid:Q5CPtCWymoBwUPLIWc1EbWlEpCo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83596 uniprotkb:O83135 intact:EBI-1589035|ensemblbacteria:AAC65569 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604024|imex:IM-9152-653 author score:0.177730034 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:64C25FD2D0E6070A|rigid:NsWF5NJmMps4f0BaSfTDs7i3A9A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83098 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1582702|ensemblbacteria:AAC65063 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y059_trepa(display_long)|uniprotkb:TP_0059(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604012|imex:IM-9152-651 author score:0.185736038 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 ensemblbacteria:AAC65063(transcript)|ensemblbacteria:TP_0059(gene)|refseq:WP_010881508.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0059|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:z0jLUZgTtWrzeqyRAc1O3F6D25s243276 intact-crc:DD96F6D46B724C95|rigid:0O7fmu8wmmG0lA06k49bjqP05sU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83627 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604036|imex:IM-9152-655 author score:0.173829605 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:AA2FF6D456FD59F8|rigid:IA7kJeQmbZCekCQ0HPK5fkXMCLY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83135 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604030|imex:IM-9152-654 author score:0.177730034 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0974|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:DCCA22EF3118FD43|rigid:okSDm2WgBhw4/EsIShSlIoq/mDI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83135 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604048|imex:IM-9152-657 author score:0.151837631 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:EA2E3DBA18CBDBCE|rigid:mdinhG0GYzkM2fF52CmG2FYSNZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83311 uniprotkb:O83135 intact:EBI-1198757|intact:EBI-1585286|ensemblbacteria:AAC65269 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83311_trepa(display_long)|uniprotkb:TP_0287(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604042|imex:IM-9152-656 author score:0.162534071 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65269(transcript)|ensemblbacteria:TP_0287(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0287|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZfA00BnKOyKdS75kE5hUBSBO0uE243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:2280E5024E5B7FB4|rigid:F1sg1bNh3CVFteJxRpy/MvNb8IA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83565 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604054|imex:IM-9152-658 author score:0.141725999 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 intact-crc:BCBF0035BA562EFC|rigid:9TQALgCXLWvCAtlpO5rgxoLpSSc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83670 uniprotkb:O83135 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604060|imex:IM-9152-659 author score:0.138482636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:E9F6D70F7250657D|rigid:P1yyLcbgBK7SW0USXoXnXV2QxG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83805 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604066|imex:IM-9152-660 author score:0.138482636 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:8035622B7DF9DB4F|rigid:4FM94NTvxzCbHL5/hn0GnG9d/4c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83738 uniprotkb:O83135 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604072|imex:IM-9152-661 author score:0.132182807 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:BDBF10F2A2C2888D|rigid:P9+F2SCoLXvBMiKpguyXygUgbe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83709 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604078|imex:IM-9152-662 author score:0.104235949 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 intact-crc:FC0BADA7F3641D50|rigid:vgAvMJRbtNdUI/yQFe7Wk7Mwld8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83305 uniprotkb:O83135 intact:EBI-1582887|ensemblbacteria:AAC65278 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604084|imex:IM-9152-663 author score:0.06688058 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:7672FFCD3147E34D|rigid:sMoWoN/8B9dQeZO/TeZQB64D404 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83398 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198346|intact:EBI-1581899|ensemblbacteria:AAC65367 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:mraz_trepa(display_long)|uniprotkb:mraZ(gene name)|psi-mi:mraZ(display_short)|uniprotkb:TP_0383(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604090|imex:IM-9152-664 author score:0.065219879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR003444(MraZ)|interpro:IPR020603|interpro:IPR007159(SpoVT/AbrB-like, predicted transcription regulator)|interpro:IPR038619|refseq:WP_010881831.1|interpro:IPR037914|ensemblbacteria:AAC65367(transcript)|ensemblbacteria:TP_0383(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009295"(nucleoid)|interpro:IPR035642|interpro:IPR035644 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0383|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:MehaA12LSPndG7CxQ/nmnV6Oy78243276 intact-crc:70278F7996F2DAC7|rigid:zY9sdeQZPsYjaiTx11458kGfuRA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83982 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604096|imex:IM-9152-665 author score:0.065219879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:9FA0CB0235446286|rigid:THGDXm3mZ7vOaoINE3DYo2s5arA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83135 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604114|imex:IM-9152-668 author score:0.051914365 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:B58A0E0FACB86CD8|rigid:vkfxjf7hsLKkPGIq/dARGEffB7U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83135 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604102|imex:IM-9152-666 author score:0.063418216 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:946F65B79D017202|rigid:D/3Rhg8AmJHQ6LQyvCF+YwfKAuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83135 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604108|imex:IM-9152-667 author score:0.05747787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:F4E48202C4FADACC|rigid:VCqvwbnFkuVX1LwusEqnIqNfPb8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83877 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604120|imex:IM-9152-669 author score:0.035549608 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:BFAE9A9881A362B4|rigid:EvJIvdaFzXipp2wPzWv1UUv3yVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83667 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604138|imex:IM-9152-672 author score:0.016914651 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:CF4925326E47ED2C|rigid:guwbuxim1dAMNOVgvpmmRf4l/Zg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83574 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604126|imex:IM-9152-670 author score:0.031787565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:FE808253BD0F7387|rigid:e9S2URUcdVgO3JUP6rq+FvpUHGg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83413 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604132|imex:IM-9152-671 author score:0.018311436 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:8195166285C8CF68|rigid:O8vw/eXr6eg3R24AAfMvimJNR8Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83135 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604144|imex:IM-9152-673 author score:0.01135864 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:EBA1ECB2C600DDC1|rigid:Y0aRwbmGhjyRK4AtumTynphcfQM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83745 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604150|imex:IM-9152-674 author score:0.009426023 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:482D4178CDD89526|rigid:+qVpy2AkKysM7kpTHaW7V2+S25A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83282 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604156|imex:IM-9152-675 author score:0.003795356 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:194A5FADC4C5B601|rigid:3pWMQl7FyZSkmZwoxxGUNC+cZI4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83135 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604162|imex:IM-9152-676 author score:0.003145501 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:0D3558903FE50288|rigid:MurZ0k4aijlR2OLWNmcSBX1GjSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83932 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1587347|ensemblbacteria:AAC65924 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:y966_trepa(display_long)|uniprotkb:TP_0966(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604180|imex:IM-9152-679 author score:0.274314116 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 ensemblbacteria:AAC65924(transcript)|ensemblbacteria:TP_0966(gene)|refseq:WP_010882410.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0966; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:H5jKNl5bFmPC5m+gwSHyZKnM5os243276 intact-crc:2EA484ECA7C8B2DE|rigid:L5e67hlcto6qpha/NXn9HYu3ubE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83135 uniprotkb:O83958 intact:EBI-1583625|ensemblbacteria:AAC65092 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604168|imex:IM-9152-677 author score:0.000186761 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0097; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:CB1915DF9949F8C2|rigid:5gZZr1tW0cEeIUmW/Xb+12pNHrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83070 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1198290|intact:EBI-1581545|ensemblbacteria:AAC65020|ensemblbacteria:AGN75247 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:o83070_trepa(display_long)|uniprotkb:TP_0026(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604174|imex:IM-9152-678 author score:0.274314116 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR000090(Flagellar motor switch protein FliG)|interpro:IPR011002(Flagellar motor switch protein FliG, alpha-helical)|interpro:IPR032779|interpro:IPR023087|interpro:IPR028263|refseq:WP_010881475.1|ensemblbacteria:AAC65020(transcript)|ensemblbacteria:AGN75247(transcript)|ensemblbacteria:TP_0026(gene)|ensemblbacteria:TPANIC_0026(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0026; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:USZwF2R3cf0tsIaz8dL9apgqM6c243276 intact-crc:08545E48D3D5CD12|rigid:4Vf0TirI+6y90fxDqRmI9Z5q8wA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83460 uniprotkb:O83413 intact:EBI-1604190|ensemblbacteria:AAC65433 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:ispg_trepa(display_long)|uniprotkb:ispG(gene name)|psi-mi:ispG(display_short)|uniprotkb:"1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase"(gene name synonym)|uniprotkb:TP_0446(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604186|imex:IM-9152-680 author score:0.266177199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016425(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial)|interpro:IPR004588(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type)|ensemblbacteria:AAC65433(transcript)|ensemblbacteria:TP_0446(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046429"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR011005(Dihydropteroate synthase-like) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0446; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0MEudGNBf2098OCiRW+QGr0cJy0243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:441FD76304E94A12|rigid:eCUedIHTE+mFHtXGrcICMfYPUIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83460 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1604190|ensemblbacteria:AAC65433 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:ispg_trepa(display_long)|uniprotkb:ispG(gene name)|psi-mi:ispG(display_short)|uniprotkb:"1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase"(gene name synonym)|uniprotkb:TP_0446(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604196|imex:IM-9152-681 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR016425(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial)|interpro:IPR004588(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type)|ensemblbacteria:AAC65433(transcript)|ensemblbacteria:TP_0446(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016114"(terpenoid biosynthetic process)|go:"GO:0019288"(isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway)|go:"GO:0046429"(4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR011005(Dihydropteroate synthase-like) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0446; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:0MEudGNBf2098OCiRW+QGr0cJy0243276 intact-crc:86B11810F1862E14|rigid:M6d4S3qzqkx+ponKBkbUZIZCmCc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83055 uniprotkb:O83574 intact:EBI-1604206|ensemblbacteria:AAC65006|ensemblbacteria:AGN75235 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83055_trepa(display_long)|uniprotkb:TP_0011(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604202|imex:IM-9152-682 author score:0.262019574 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|refseq:WP_010881460.1|ensemblbacteria:AAC65006(transcript)|ensemblbacteria:AGN75235(transcript)|ensemblbacteria:TP_0011(gene)|ensemblbacteria:TPANIC_0011(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0011; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:C6ncdhW7RhixrlXHEaiJd+xf7Jg243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:C5C30F931B711E0F|rigid:iUnHPdgK/H/pXHWN8xhgYzF/guk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83055 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1604206|ensemblbacteria:AAC65006|ensemblbacteria:AGN75235 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83055_trepa(display_long)|uniprotkb:TP_0011(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604211|imex:IM-9152-683 author score:0.156878757 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|refseq:WP_010881460.1|ensemblbacteria:AAC65006(transcript)|ensemblbacteria:AGN75235(transcript)|ensemblbacteria:TP_0011(gene)|ensemblbacteria:TPANIC_0011(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0011; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:C6ncdhW7RhixrlXHEaiJd+xf7Jg243276 intact-crc:866992B74A9EFE44|rigid:NEACxEMK+MeiOUK8PKgBldJIOn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83653 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1604217|ensemblbacteria:AAC65620 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:sys_trepa(display_long)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:TP_0647(locus name)|uniprotkb:Seryl-tRNA synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604221|imex:IM-9152-684 author score:0.262019574 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR033729|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|refseq:WP_010882092.1|ensemblbacteria:AAC65620(transcript)|ensemblbacteria:TP_0647(gene)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0016260"(selenocysteine biosynthetic process)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|interpro:IPR042103 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0647; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:0p6FjVjczH6f9AEXu2Esq4IjMuk243276 intact-crc:A04C8457DB5FD648|rigid:vfKyizgaboFjsQ9q12un+Ir+hig false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83721 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586911|ensemblbacteria:AGN75913|ensemblbacteria:AAC65707 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83721_trepa(display_long)|uniprotkb:TP_0739(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604239|imex:IM-9152-687 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004474(Cell envelope-related transcriptional attenuator)|ensemblbacteria:AAC65707(transcript)|ensemblbacteria:AGN75913(transcript)|ensemblbacteria:TP_0739(gene)|ensemblbacteria:TPANIC_0739(gene)|refseq:WP_010882184.1|interpro:IPR027381 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0739; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:i2D9xp91VVSHufLpK1JhOHaeFeA243276 intact-crc:E53F3376A6C656F4|rigid:r0L76cBPb142AmKkHga216yS4f4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83653 uniprotkb:O83767 intact:EBI-1604217|ensemblbacteria:AAC65620 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:sys_trepa(display_long)|uniprotkb:serS(gene name)|psi-mi:serS(display_short)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:TP_0647(locus name)|uniprotkb:Seryl-tRNA synthetase(gene name synonym) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604227|imex:IM-9152-685 author score:0.110516645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033729|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR010978(tRNA-binding arm)|refseq:WP_010882092.1|ensemblbacteria:AAC65620(transcript)|ensemblbacteria:TP_0647(gene)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0016260"(selenocysteine biosynthetic process)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|interpro:IPR042103 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0647; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:0p6FjVjczH6f9AEXu2Esq4IjMuk243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0C8A3EE36E3D4251|rigid:ZJAe8/9XX5eOX/XXlRWXCxVDe6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83721 uniprotkb:O83574 intact:EBI-1586911|ensemblbacteria:AGN75913|ensemblbacteria:AAC65707 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83721_trepa(display_long)|uniprotkb:TP_0739(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604233|imex:IM-9152-686 author score:0.262019574 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004474(Cell envelope-related transcriptional attenuator)|ensemblbacteria:AAC65707(transcript)|ensemblbacteria:AGN75913(transcript)|ensemblbacteria:TP_0739(gene)|ensemblbacteria:TPANIC_0739(gene)|refseq:WP_010882184.1|interpro:IPR027381 interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0739; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:i2D9xp91VVSHufLpK1JhOHaeFeA243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:201F9DD63E582683|rigid:PJhdEgBY81mVdjsWV6m++xW1P5s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83524 uniprotkb:O83927 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604248|imex:IM-9152-688 author score:0.260414641 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:A42D12FD9305EB46|rigid:zkWSKoo+MCKbbZ3uyTuaAWZxS80 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83524 uniprotkb:O83877 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604254|imex:IM-9152-689 author score:0.14883104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:49CF070F53C688FF|rigid:bXOfOS576lRxfi6l9gt786a6Aqg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83524 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604260|imex:IM-9152-690 author score:0.088177508 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 intact-crc:028FFB88CCB77021|rigid:1/fnMjHUdz/8trPc36kZVcuuIc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83524 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604266|imex:IM-9152-691 author score:0.031071045 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 intact-crc:039D1BE5CAD50B4B|rigid:WiB4jtsj+3mhp8WiWnHU+kN4ej4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83524 uniprotkb:O83954 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604272|imex:IM-9152-692 author score:0.02587223 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:674D81E7E2F3DD4B|rigid:qHrkyaNNzHTJyEZtjQ98t5CU/DM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83524 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1604245|ensemblbacteria:AAC65499|ensemblbacteria:AGN75700 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83524_trepa(display_long)|uniprotkb:TP_0511(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604278|imex:IM-9152-693 author score:0.001569806 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003711(Transcription factor CarD)|interpro:IPR042215|ensemblbacteria:AAC65499(transcript)|ensemblbacteria:TP_0511(gene)|ensemblbacteria:TPANIC_0511(gene)|ensemblbacteria:AGN75700(transcript)|interpro:IPR036101 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0511; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:8KrT5A4zU/hAq4AAeM+gIRwAb5M243276 intact-crc:CF34832A82CDA28E|rigid:0pV7jeWWQiYiEk57BTFkLCggPtU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83877 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604284|imex:IM-9152-694 author score:0.228214147 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0060; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:0784A6EE7B9A130F|rigid:emYIGc37sbHZPleUU04+oQmmmqo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83958 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604302|imex:IM-9152-697 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0060; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D9F174F5DA671ED6|rigid:n4Yhd1yvk7VkpRcCjtaRO2OEowM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83099 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604290|imex:IM-9152-695 author score:0.188548673 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0060; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:91814AED9579D8B7|rigid:fFwjbBeaZwEN1yfUXFxxyydM9BE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83099 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1582052|ensemblbacteria:AAC65055 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604296|imex:IM-9152-696 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0060; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 intact-crc:29F72B1886B7347A|rigid:QDZ7QnjinZDQHOfaCw0wUB7HiN8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83729 uniprotkb:O83574 intact:EBI-1604308|ensemblbacteria:AAC65718 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:y747_trepa(display_long)|uniprotkb:TP_0747(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604311|imex:IM-9152-698 author score:0.227327748 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882192.1|ensemblbacteria:AAC65718(transcript)|ensemblbacteria:TP_0747(gene) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0747; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ktz+QaAU/YNPm2+5NSD3mb1r62w243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:69B6B0FBC1F2B7CD|rigid:vM7p1VP7V50eN4BszarJUgdrG8w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83729 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1604308|ensemblbacteria:AAC65718 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y747_trepa(display_long)|uniprotkb:TP_0747(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604317|imex:IM-9152-699 author score:0.15694401 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010882192.1|ensemblbacteria:AAC65718(transcript)|ensemblbacteria:TP_0747(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0747; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:Ktz+QaAU/YNPm2+5NSD3mb1r62w243276 intact-crc:9BC1E81E31D1DBF2|rigid:+8WOtZzqnW7aX+4+fZfkkR5ryWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83729 uniprotkb:O83282 intact:EBI-1604308|ensemblbacteria:AAC65718 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y747_trepa(display_long)|uniprotkb:TP_0747(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604323|imex:IM-9152-945 author score:0.033013747 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882192.1|ensemblbacteria:AAC65718(transcript)|ensemblbacteria:TP_0747(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0747; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ktz+QaAU/YNPm2+5NSD3mb1r62w243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:E1F75D8E9EFD3772|rigid:KKUg/x6mAnjBpTM8MOuT10rzOL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83729 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1604308|ensemblbacteria:AAC65718 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:y747_trepa(display_long)|uniprotkb:TP_0747(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604329|imex:IM-9152-701 author score:0.027499104 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) refseq:WP_010882192.1|ensemblbacteria:AAC65718(transcript)|ensemblbacteria:TP_0747(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0747; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Ktz+QaAU/YNPm2+5NSD3mb1r62w243276 intact-crc:3295F7851C32F2BA|rigid:KIr6lxrAGexuS2BFkPo52Rd84HY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83729 uniprotkb:O83958 intact:EBI-1604308|ensemblbacteria:AAC65718 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y747_trepa(display_long)|uniprotkb:TP_0747(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604335|imex:IM-9152-702 author score:0.001671139 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882192.1|ensemblbacteria:AAC65718(transcript)|ensemblbacteria:TP_0747(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0747; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ktz+QaAU/YNPm2+5NSD3mb1r62w243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:BB72988402081DC7|rigid:p1HNQvIvCez8JxN7LSvWp5ijJT0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83757 uniprotkb:O83877 intact:EBI-1604345|ensemblbacteria:AAC65746|ensemblbacteria:AGN75951 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:o83757_trepa(display_long)|uniprotkb:TP_0778(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604341|imex:IM-9152-703 author score:0.217654884 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004518(NTP pyrophosphohydrolase MazG, putative catalytic core)|interpro:IPR011551(NTP pyrophosphohydrolase MazG, bacterial)|refseq:WP_010882223.1|ensemblbacteria:AAC65746(transcript)|ensemblbacteria:AGN75951(transcript)|ensemblbacteria:TP_0778(gene)|ensemblbacteria:TPANIC_0778(gene) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0778; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rJaTu84QUWhrSf9i96j08z+k+CU243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:C9654B09D6CFE7E1|rigid:fw8rPY/hlk528dOkGzFa2tbS5eE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83757 uniprotkb:O83282 intact:EBI-1604345|ensemblbacteria:AAC65746|ensemblbacteria:AGN75951 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83757_trepa(display_long)|uniprotkb:TP_0778(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604350|imex:IM-9152-704 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004518(NTP pyrophosphohydrolase MazG, putative catalytic core)|interpro:IPR011551(NTP pyrophosphohydrolase MazG, bacterial)|refseq:WP_010882223.1|ensemblbacteria:AAC65746(transcript)|ensemblbacteria:AGN75951(transcript)|ensemblbacteria:TP_0778(gene)|ensemblbacteria:TPANIC_0778(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0778; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rJaTu84QUWhrSf9i96j08z+k+CU243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:7BA6993574CBAE16|rigid:ZG4+kqCZiBax2dex1WczFMLhQ3Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83757 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1604345|ensemblbacteria:AAC65746|ensemblbacteria:AGN75951 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83757_trepa(display_long)|uniprotkb:TP_0778(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604356|imex:IM-9152-705 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR004518(NTP pyrophosphohydrolase MazG, putative catalytic core)|interpro:IPR011551(NTP pyrophosphohydrolase MazG, bacterial)|refseq:WP_010882223.1|ensemblbacteria:AAC65746(transcript)|ensemblbacteria:AGN75951(transcript)|ensemblbacteria:TP_0778(gene)|ensemblbacteria:TPANIC_0778(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0778; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:rJaTu84QUWhrSf9i96j08z+k+CU243276 intact-crc:1E2741016BEEF0C9|rigid:rHHeu6jYNQNduZyM/ClGnjKsslA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83757 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1604345|ensemblbacteria:AAC65746|ensemblbacteria:AGN75951 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83757_trepa(display_long)|uniprotkb:TP_0778(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604362|imex:IM-9152-706 author score:0.002519196 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004518(NTP pyrophosphohydrolase MazG, putative catalytic core)|interpro:IPR011551(NTP pyrophosphohydrolase MazG, bacterial)|refseq:WP_010882223.1|ensemblbacteria:AAC65746(transcript)|ensemblbacteria:AGN75951(transcript)|ensemblbacteria:TP_0778(gene)|ensemblbacteria:TPANIC_0778(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0778; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:rJaTu84QUWhrSf9i96j08z+k+CU243276 intact-crc:4C56177CDE723740|rigid:3j5t4LEXmZAgLhNbo5f8O2swPGI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83624 uniprotkb:O83574 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604371|imex:IM-9152-707 author score:0.206071282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 intact-crc:3B6BA0CAFFDFDDD6|rigid:XiXR6cxBmePobuRCOnwnN83hpVo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83624 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604377|imex:IM-9152-708 author score:0.141067282 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 intact-crc:211E8BADECEB946C|rigid:ZqDPmfExgnJMI19tJb9tf1UFmDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83624 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604383|imex:IM-9152-709 author score:0.119738274 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 intact-crc:3C6710D6F7526725|rigid:3gfqZJ/ZRWy5AkwO7LNQYg7z878 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83624 uniprotkb:O83954 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604401|imex:IM-9152-712 author score:0.024339195 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:1C572388DDDEEE8D|rigid:y4Oo4VPzJUtIjOSBiWxszHPod/8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83624 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604389|imex:IM-9152-710 author score:0.083268209 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 intact-crc:5DF33E0DBD2D4C86|rigid:PY7dyfFe/SaMrqp9YflYrFs1VCU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83624 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604395|imex:IM-9152-711 author score:0.029239206 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 intact-crc:B3B050D510DA1B20|rigid:gkgP9P69uqnNIJ8SyaSVDQxkvuo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83624 uniprotkb:O83958 intact:EBI-1604368|ensemblbacteria:AAC65591|ensemblbacteria:AGN75796 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83624_trepa(display_long)|uniprotkb:TP_0615(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604407|imex:IM-9152-713 author score:0.001474609 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|refseq:WP_010882061.1|ensemblbacteria:AAC65591(transcript)|ensemblbacteria:AGN75796(transcript)|ensemblbacteria:TP_0615(gene)|ensemblbacteria:TPANIC_0615(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0615; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pku863QnIvtLQb2wpyX9OT+RmcY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:6945501D3F135F49|rigid:mU7pywJGuOPDygfL7J5WsYJlkX4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83691 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1604417|ensemblbacteria:AAC65665 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y693_trepa(display_long)|uniprotkb:TP_0693(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604413|imex:IM-9152-714 author score:0.19301682 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 refseq:WP_010882138.1|ensemblbacteria:AAC65665(transcript)|ensemblbacteria:TP_0693(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0693; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:gQBlKAKOdiQ7HQKaqq11vYMtr8g243276 intact-crc:3AF53ECF59787F85|rigid:3fxo7zb1OWOFpzJPAK1q0Swj9cQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83453 uniprotkb:O83745 intact:EBI-1604422|ensemblbacteria:AAC65426 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:chew_trepa(display_long)|uniprotkb:cheW(gene name)|psi-mi:cheW(display_short)|uniprotkb:TP_0439(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604426|imex:IM-9152-715 author score:0.184671014 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002545(CheW-like protein)|ensemblbacteria:AAC65426(transcript)|ensemblbacteria:TP_0439(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|interpro:IPR036061|interpro:IPR039315 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0439; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a+i9Na2WeWN5M4SnDxbl4BRXPA0243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:44C7F55B0B129F61|rigid:31XJ7T9Lkj+Cg2OAhX8Yvi/rxMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83453 uniprotkb:O83767 intact:EBI-1604422|ensemblbacteria:AAC65426 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:chew_trepa(display_long)|uniprotkb:cheW(gene name)|psi-mi:cheW(display_short)|uniprotkb:TP_0439(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604432|imex:IM-9152-716 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002545(CheW-like protein)|ensemblbacteria:AAC65426(transcript)|ensemblbacteria:TP_0439(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|interpro:IPR036061|interpro:IPR039315 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0439; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a+i9Na2WeWN5M4SnDxbl4BRXPA0243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:D3A5B64A49C77AD0|rigid:phH5Gd10BTkdvR/6ZMLWRGovL1w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83453 uniprotkb:O83282 intact:EBI-1604422|ensemblbacteria:AAC65426 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:chew_trepa(display_long)|uniprotkb:cheW(gene name)|psi-mi:cheW(display_short)|uniprotkb:TP_0439(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604438|imex:IM-9152-717 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002545(CheW-like protein)|ensemblbacteria:AAC65426(transcript)|ensemblbacteria:TP_0439(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|interpro:IPR036061|interpro:IPR039315 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0439; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a+i9Na2WeWN5M4SnDxbl4BRXPA0243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:2602D1ADED5697F6|rigid:XouSF6MX6v3s9VO32xmfWFSlf1s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83050 uniprotkb:O83877 intact:EBI-1584836|ensemblbacteria:AAC65005 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:y004_trepa(display_long)|uniprotkb:TP_0004(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604444|imex:IM-9152-718 author score:0.183444879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007922(Protein of unknown function DUF721)|ensemblbacteria:AAC65005(transcript)|ensemblbacteria:TP_0004(gene)|refseq:WP_010881454.1 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0004; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IxAoquYRvbXKT9V9t6ETfHG8dHo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:BC806EC17A99082F|rigid:ATd5tRZK1DyI1hZ1uaNLPeo/Dd8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83050 uniprotkb:O83282 intact:EBI-1584836|ensemblbacteria:AAC65005 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y004_trepa(display_long)|uniprotkb:TP_0004(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604450|imex:IM-9152-719 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007922(Protein of unknown function DUF721)|ensemblbacteria:AAC65005(transcript)|ensemblbacteria:TP_0004(gene)|refseq:WP_010881454.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0004; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IxAoquYRvbXKT9V9t6ETfHG8dHo243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:680E1733F937C9CC|rigid:67sXFAHN7rRdLSShWgL/lOFG5Zo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83877 uniprotkb:O83819 intact:EBI-1581925|ensemblbacteria:AAC65859 intact:EBI-1604456|ensemblbacteria:AAC65820 psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:y847_trepa(display_long)|uniprotkb:TP_0847(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604459|imex:IM-9152-720 author score:0.183444879 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 ensemblbacteria:AAC65820(transcript)|ensemblbacteria:TP_0847(gene)|refseq:WP_010882291.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0847; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 rogid:vMrJp1sRwSLVk1WNPAuguYBTM/U243276 intact-crc:976996522F877733|rigid:gRUzpWda3QLWw+D0+sF6yu+9n1U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83819 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1604456|ensemblbacteria:AAC65820 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y847_trepa(display_long)|uniprotkb:TP_0847(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604465|imex:IM-9152-721 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65820(transcript)|ensemblbacteria:TP_0847(gene)|refseq:WP_010882291.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0847; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:vMrJp1sRwSLVk1WNPAuguYBTM/U243276 intact-crc:1922592F3928B5BB|rigid:gdbEw7xpK8GQo4b1cSgPzDnlR/M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83241 uniprotkb:O83413 intact:EBI-1604471|ensemblbacteria:AAC65200 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:rs11_trepa(display_long)|uniprotkb:rpsK(gene name)|psi-mi:rpsK(display_short)|uniprotkb:TP_0211(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604475|imex:IM-9152-722 author score:0.176794854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001971(Ribosomal protein S11)|interpro:IPR019981|refseq:WP_010881659.1|ensemblbacteria:AAC65200(transcript)|ensemblbacteria:TP_0211(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR036967 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0211; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kwvyd2/exTyZ5UKKgxDvZ0MvJw4243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:1414559D581080EB|rigid:CxrI2eBXcV4WxuSu0ZgxJtBkHNY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83243 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1604485|ensemblbacteria:AAC65202 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:rl17_trepa(display_long)|uniprotkb:rplQ(gene name)|psi-mi:rplQ(display_short)|uniprotkb:TP_0213(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604481|imex:IM-9152-723 author score:0.176794854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR000456(Ribosomal protein L17)|refseq:WP_010881661.1|ensemblbacteria:AAC65202(transcript)|ensemblbacteria:TP_0213(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036373 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0213; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:TtXchlJOwd+EmsTbWJIv38bqSHo243276 intact-crc:3E09971426254395|rigid:HBVEsKoP05dHuSn0P5p1Bqb45bk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83616 uniprotkb:O83413 intact:EBI-1604495|ensemblbacteria:AAC65583 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:y607_trepa(display_long)|uniprotkb:TP_0607(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604491|imex:IM-9152-724 author score:0.176794854 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65583(transcript)|ensemblbacteria:TP_0607(gene) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0607; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Wlw4mclHzfDfJRUUN5S/xvRR41k243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:E34287F26B9C3E72|rigid:8TRAfIRWCFVM6tjKn2BxdiMyo6w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83083 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1587036|ensemblbacteria:AAC65037|ensemblbacteria:AGN75263 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83083_trepa(display_long)|uniprotkb:TP_0043(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604500|imex:IM-9152-725 author score:0.172049621 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR023346|interpro:IPR008258(Lytic transglycosylase-like, catalytic)|ensemblbacteria:AAC65037(transcript)|ensemblbacteria:AGN75263(transcript)|ensemblbacteria:TP_0043(gene)|ensemblbacteria:TPANIC_0043(gene)|refseq:WP_010881492.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0043; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:L5c/hn/KYHaZ7OiMJh6wEgilZZg243276 intact-crc:5DAE3658ECCDC118|rigid:WxgGK7UhoNxDWq/FNlCvrr/mTFU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83244 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1589531|ensemblbacteria:AAC65210 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:y214_trepa(display_long)|uniprotkb:TP_0214(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604506|imex:IM-9152-726 author score:0.167860044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) ensemblbacteria:AAC65210(transcript)|ensemblbacteria:TP_0214(gene)|refseq:WP_010881662.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0214; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:HAC6HFUlZSuAKwcd7O49uTZBi/M243276 intact-crc:56F8DAFF54F1FFE8|rigid:BC4G3TQdywaLVAfcPTP7OiHselU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83244 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1589531|ensemblbacteria:AAC65210 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y214_trepa(display_long)|uniprotkb:TP_0214(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604512|imex:IM-9152-727 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65210(transcript)|ensemblbacteria:TP_0214(gene)|refseq:WP_010881662.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0214; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:HAC6HFUlZSuAKwcd7O49uTZBi/M243276 intact-crc:ECEE4A2DA1D7E4DD|rigid:snKtFNP++PYPdKaASe5c0nxhrrY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83821 uniprotkb:O83413 intact:EBI-1604533|ensemblbacteria:AAC65815 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:rl35_trepa(display_long)|uniprotkb:rpmI(gene name)|psi-mi:rpmI(display_short)|uniprotkb:TP_0849(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604537|imex:IM-9152-730 author score:0.167860044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021137|interpro:IPR018265|interpro:IPR001706(Ribosomal protein L35)|refseq:WP_010882293.1|ensemblbacteria:AAC65815(transcript)|ensemblbacteria:TP_0849(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR037229 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0849; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pBJtKC9wQ4Md/v/n9ysrP+iXABI243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:133748EA9684CCA8|rigid:Lvqfno/3rFiqN+n8PLsMnOn91vU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83422 uniprotkb:O83413 intact:EBI-1604518|ensemblbacteria:AAC65394 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83422_trepa(display_long)|uniprotkb:TP_0407(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604521|imex:IM-9152-728 author score:0.167860044 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR041492|ensemblbacteria:AAC65394(transcript)|ensemblbacteria:TP_0407(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881855.1|interpro:IPR036412 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0407; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:UeMfQI+myY31/ZThmm3qeu53jaM243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:921C71B871E54EC4|rigid:m/5x7J7zhxT6cCWh0/41ZZ+XPe4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83422 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1604518|ensemblbacteria:AAC65394 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83422_trepa(display_long)|uniprotkb:TP_0407(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604527|imex:IM-9152-729 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR041492|ensemblbacteria:AAC65394(transcript)|ensemblbacteria:TP_0407(gene)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881855.1|interpro:IPR036412 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0407; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:UeMfQI+myY31/ZThmm3qeu53jaM243276 intact-crc:6E7E0DC2C661FFCD|rigid:qNQmyEC7pogpzVXnfWZv9F5Iwio false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83821 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1604533|ensemblbacteria:AAC65815 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl35_trepa(display_long)|uniprotkb:rpmI(gene name)|psi-mi:rpmI(display_short)|uniprotkb:TP_0849(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604543|imex:IM-9152-731 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR021137|interpro:IPR018265|interpro:IPR001706(Ribosomal protein L35)|refseq:WP_010882293.1|ensemblbacteria:AAC65815(transcript)|ensemblbacteria:TP_0849(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR037229 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0849; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:pBJtKC9wQ4Md/v/n9ysrP+iXABI243276 intact-crc:B88891E7E7F301C8|rigid:As0vgU6K1uCIgfPgnMs1A0b8ORA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83065 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1604553|ensemblbacteria:AAC65021 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:y021_trepa(display_long)|uniprotkb:TP_0021(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604549|imex:IM-9152-732 author score:0.165345199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 refseq:WP_010881470.1|ensemblbacteria:AAC65021(transcript)|ensemblbacteria:TP_0021(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0021; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:3P4X0d0uV+zzn/b1c4zqCBT+gxo243276 intact-crc:9815E98C0E04B8C6|rigid:ckVTpp1NT72aZqp8EWoQHAjHKds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83325 uniprotkb:O83667 intact:EBI-1604562|ensemblbacteria:AAC65291 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:mutl_trepa(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:TP_0303(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604558|imex:IM-9152-733 author score:0.165345199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038973|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020667|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|ensemblbacteria:AAC65291(transcript)|ensemblbacteria:TP_0303(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|interpro:IPR036890|interpro:IPR037198|interpro:IPR042120|interpro:IPR042121 ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0303; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JZVsq2xf6/r+ZRHIB5PKcTtdVLc243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:3911FD1A3D31146D|rigid:eZQpn7q1PTMYNcX2nqB9qZ7Db6I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83362 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1584754|ensemblbacteria:AAC65330 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:kcy_trepa(display_long)|uniprotkb:cmk(gene name)|psi-mi:cmk(display_short)|uniprotkb:Cytidine monophosphate kinase(gene name synonym)|uniprotkb:TP_0342(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604568|imex:IM-9152-734 author score:0.165345199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR011892(Cytidylate kinase, putative)|ensemblbacteria:AAC65330(transcript)|ensemblbacteria:TP_0342(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0036430"(CMP kinase activity)|go:"GO:0036431"(dCMP kinase activity)|interpro:IPR027417|interpro:IPR011994(Cytidylate kinase region) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0342; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:1643bjgy8ivHZTvvgo/QzspBeqw243276 intact-crc:C58D6040148FDBD0|rigid:ymEE0QYGi6lc5lS986QTY2tD0pI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83410 uniprotkb:O83667 intact:EBI-1604578|ensemblbacteria:AAC65379|ensemblbacteria:AGN75589 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:o83410_trepa(display_long)|uniprotkb:xerC(gene name)|psi-mi:xerC(display_short)|uniprotkb:TP_0395(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604574|imex:IM-9152-735 author score:0.165345199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013762(Integrase-like, catalytic core, phage)|interpro:IPR002104(Integrase, catalytic core, phage)|interpro:IPR004107(Integrase, N-terminal SAM-like, phage)|interpro:IPR023009|interpro:IPR044068|refseq:WP_010881843.1|ensemblbacteria:AAC65379(transcript)|ensemblbacteria:AGN75589(transcript)|ensemblbacteria:TP_0395(gene)|ensemblbacteria:TPANIC_0395(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006313"(transposition, DNA-mediated)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009037"(tyrosine-based site-specific recombinase activity)|go:"GO:0051301"(cell division)|interpro:IPR010998(Integrase, Lamba-type, N-terminal) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0395; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cSWmPbs7Yng/Wa+JocDZVQZQMU0243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:2976E55716576C4C|rigid:2Pn7FZKu1hEgMnE0MwkJcPu2PCA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O06686 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1586713|uniprotkb:Q7DFP8 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:o06686_trepl(display_long)|uniprotkb:FA889_01180(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604595|imex:IM-9152-738 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 rcsb pdb:6MLX|interpro:IPR026906|interpro:IPR032675|refseq:WP_010881673.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0225; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:mpR2IjBlohP7UHj/JdxS2qfVado160 intact-crc:07F5FF20521291A2|rigid:iEH2yMShAz4LADarIKyhOk3bmt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83789 uniprotkb:O83667 intact:EBI-1583765|ensemblbacteria:AAC65785 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y813_trepa(display_long)|uniprotkb:TP_0813(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604583|imex:IM-9152-736 author score:0.165345199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65785(transcript)|ensemblbacteria:TP_0813(gene) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0813; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:wL71DWwNtjOq2v6Bj7n8xyMImTI243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:0323E6CF694ED727|rigid:b7mC3kP9aXGPFjGrW9VAjeZ4U9o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O06686 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1586713|uniprotkb:Q7DFP8 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o06686_trepl(display_long)|uniprotkb:FA889_01180(orf name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604589|imex:IM-9152-737 author score:0.159289405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) rcsb pdb:6MLX|interpro:IPR026906|interpro:IPR032675|refseq:WP_010881673.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0225; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:mpR2IjBlohP7UHj/JdxS2qfVado160 intact-crc:091449F06D4D243B|rigid:PSibVUM8+7IjqR5cJeW4a2UFckQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O06686 uniprotkb:O83282 intact:EBI-1586713|uniprotkb:Q7DFP8 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o06686_trepl(display_long)|uniprotkb:FA889_01180(orf name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604601|imex:IM-9152-739 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6MLX|interpro:IPR026906|interpro:IPR032675|refseq:WP_010881673.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0225; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mpR2IjBlohP7UHj/JdxS2qfVado160 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:D4852505732369AE|rigid:AX1/Dr4i2449AdS9sNHUA7IwJk8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83553 uniprotkb:O83413 intact:EBI-1604611|ensemblbacteria:AGN75729|ensemblbacteria:AAC65526 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:pfp_trepa(display_long)|uniprotkb:6-phosphofructokinase, pyrophosphate dependent(gene name synonym)|uniprotkb:PPi-dependent phosphofructokinase(gene name synonym)|uniprotkb:Pyrophosphate-dependent 6-phosphofructose-1-kinase(gene name synonym)|uniprotkb:TPANIC_0542(orf name)|uniprotkb:TP_0542(locus name)|uniprotkb:pfp(gene name)|psi-mi:pfp(display_short) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604607|imex:IM-9152-740 author score:0.159289405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011183(Pyrophosphate-dependent phosphofructokinase PfpB)|interpro:IPR022953|interpro:IPR000023(Phosphofructokinase)|refseq:WP_010881989.1|ensemblbacteria:AGN75729(transcript)|ensemblbacteria:TP_0542(gene)|ensemblbacteria:TPANIC_0542(gene)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047334"(diphosphate-fructose-6-phosphate 1-phosphotransferase activity)|ensemblbacteria:AAC65526(transcript)|interpro:IPR035966 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0542; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Dv7Bg3+ZwNXClYue1Kmb5CUEMJo243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:CB46CA5958F67C30|rigid:/cdefDyEgvh2xF6uBVKSyJTT39M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83553 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1604611|ensemblbacteria:AGN75729|ensemblbacteria:AAC65526 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:pfp_trepa(display_long)|uniprotkb:6-phosphofructokinase, pyrophosphate dependent(gene name synonym)|uniprotkb:PPi-dependent phosphofructokinase(gene name synonym)|uniprotkb:Pyrophosphate-dependent 6-phosphofructose-1-kinase(gene name synonym)|uniprotkb:TPANIC_0542(orf name)|uniprotkb:TP_0542(locus name)|uniprotkb:pfp(gene name)|psi-mi:pfp(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604616|imex:IM-9152-741 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR011183(Pyrophosphate-dependent phosphofructokinase PfpB)|interpro:IPR022953|interpro:IPR000023(Phosphofructokinase)|refseq:WP_010881989.1|ensemblbacteria:AGN75729(transcript)|ensemblbacteria:TP_0542(gene)|ensemblbacteria:TPANIC_0542(gene)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047334"(diphosphate-fructose-6-phosphate 1-phosphotransferase activity)|ensemblbacteria:AAC65526(transcript)|interpro:IPR035966 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0542; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:Dv7Bg3+ZwNXClYue1Kmb5CUEMJo243276 intact-crc:5BAD2344A38FC2C1|rigid:ZzAZJjPbnX0+t4j/XAONdbDeGXA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83553 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1604611|ensemblbacteria:AGN75729|ensemblbacteria:AAC65526 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:pfp_trepa(display_long)|uniprotkb:6-phosphofructokinase, pyrophosphate dependent(gene name synonym)|uniprotkb:PPi-dependent phosphofructokinase(gene name synonym)|uniprotkb:Pyrophosphate-dependent 6-phosphofructose-1-kinase(gene name synonym)|uniprotkb:TPANIC_0542(orf name)|uniprotkb:TP_0542(locus name)|uniprotkb:pfp(gene name)|psi-mi:pfp(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604622|imex:IM-9152-742 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR011183(Pyrophosphate-dependent phosphofructokinase PfpB)|interpro:IPR022953|interpro:IPR000023(Phosphofructokinase)|refseq:WP_010881989.1|ensemblbacteria:AGN75729(transcript)|ensemblbacteria:TP_0542(gene)|ensemblbacteria:TPANIC_0542(gene)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047334"(diphosphate-fructose-6-phosphate 1-phosphotransferase activity)|ensemblbacteria:AAC65526(transcript)|interpro:IPR035966 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0542; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:Dv7Bg3+ZwNXClYue1Kmb5CUEMJo243276 intact-crc:46A8451CA3AE2108|rigid:SbcTF5tHsRyn9h0UhkTwLgm/Nn8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83413 uniprotkb:O83784 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 intact:EBI-1604632|ensemblbacteria:AAC65773|ensemblbacteria:AGN75978 psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:o83784_trepa(display_long)|uniprotkb:TP_0806(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604628|imex:IM-9152-743 author score:0.159289405 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR003447(Methicillin resistance protein)|refseq:WP_010882251.1|ensemblbacteria:AAC65773(transcript)|ensemblbacteria:AGN75978(transcript)|ensemblbacteria:TP_0806(gene)|ensemblbacteria:TPANIC_0806(gene)|go:"GO:0016755"(aminoacyltransferase activity)|go:"GO:0044038"(cell wall macromolecule biosynthetic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0806; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 rogid:IKerbK5OxWQxjvqWIVCzK9CWA7c243276 intact-crc:DDDB4D1946264A63|rigid:+u0AxlBEVaw8HvnT/Pi65fvUH4k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83784 uniprotkb:O83954 intact:EBI-1604632|ensemblbacteria:AAC65773|ensemblbacteria:AGN75978 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83784_trepa(display_long)|uniprotkb:TP_0806(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604637|imex:IM-9152-744 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR003447(Methicillin resistance protein)|refseq:WP_010882251.1|ensemblbacteria:AAC65773(transcript)|ensemblbacteria:AGN75978(transcript)|ensemblbacteria:TP_0806(gene)|ensemblbacteria:TPANIC_0806(gene)|go:"GO:0016755"(aminoacyltransferase activity)|go:"GO:0044038"(cell wall macromolecule biosynthetic process) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0806; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IKerbK5OxWQxjvqWIVCzK9CWA7c243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:962AD86B2F6DE326|rigid:Q0DnYcdwMkxpXAA9Faw45VaNkZM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83784 uniprotkb:O83958 intact:EBI-1604632|ensemblbacteria:AAC65773|ensemblbacteria:AGN75978 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83784_trepa(display_long)|uniprotkb:TP_0806(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604643|imex:IM-9152-745 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR003447(Methicillin resistance protein)|refseq:WP_010882251.1|ensemblbacteria:AAC65773(transcript)|ensemblbacteria:AGN75978(transcript)|ensemblbacteria:TP_0806(gene)|ensemblbacteria:TPANIC_0806(gene)|go:"GO:0016755"(aminoacyltransferase activity)|go:"GO:0044038"(cell wall macromolecule biosynthetic process) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0806; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IKerbK5OxWQxjvqWIVCzK9CWA7c243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:985909121FF3033D|rigid:3nVLjEm+RaVdyi+0ENyUDG6r9Yg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83276 uniprotkb:O83667 intact:EBI-1604649|ensemblbacteria:AAC65241 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:y248_trepa(display_long)|uniprotkb:TP_0248(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604652|imex:IM-9152-746 author score:0.156878757 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|ensemblbacteria:TP_0248(gene)|ensemblbacteria:AAC65241(transcript) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0248; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yU2gDR3v1N9aZbmpGJd2qQYbs/g243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:4C1DB6A5CA4B9079|rigid:NDGOwOpLcCz419+9UXmMnYjZ378 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83693 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1604664|ensemblbacteria:AAC65662|ensemblbacteria:AGN75873 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83693_trepa(display_long)|uniprotkb:TP_0695(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604673|imex:IM-9152-749 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR040570|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_010882140.1|ensemblbacteria:AAC65662(transcript)|ensemblbacteria:AGN75873(transcript)|ensemblbacteria:TP_0695(gene)|ensemblbacteria:TPANIC_0695(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR041472 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0695; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:krOWb6DNuWdvF70TjBMeTpIytVk243276 intact-crc:6458A0D8DF81D3B1|rigid:gi3PpN6zYkZN299GsQQXx40kpys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83276 uniprotkb:O83958 intact:EBI-1604649|ensemblbacteria:AAC65241 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y248_trepa(display_long)|uniprotkb:TP_0248(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604658|imex:IM-9152-747 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005886"(plasma membrane)|ensemblbacteria:TP_0248(gene)|ensemblbacteria:AAC65241(transcript) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0248; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:yU2gDR3v1N9aZbmpGJd2qQYbs/g243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B83B51F8AF93C2D9|rigid:07jouGx4+sz5QuxnV0U6QmYjnF4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83693 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1604664|ensemblbacteria:AAC65662|ensemblbacteria:AGN75873 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83693_trepa(display_long)|uniprotkb:TP_0695(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604667|imex:IM-9152-748 author score:0.156878757 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR040570|interpro:IPR013815(ATP-grasp fold, subdomain 1)|refseq:WP_010882140.1|ensemblbacteria:AAC65662(transcript)|ensemblbacteria:AGN75873(transcript)|ensemblbacteria:TP_0695(gene)|ensemblbacteria:TPANIC_0695(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR041472 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0695; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:krOWb6DNuWdvF70TjBMeTpIytVk243276 intact-crc:D627B6FFB1155872|rigid:nP9dgzcM9MgQDBLk2UczOXp7aV0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83135 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1583625|ensemblbacteria:AAC65092 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:if1_trepa(display_long)|uniprotkb:infA(gene name)|psi-mi:infA(display_short)|uniprotkb:TP_0097(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604679|imex:IM-9152-750 author score:0.155393632 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65092(transcript)|ensemblbacteria:TP_0097(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR006196(S1, IF1 type)|interpro:IPR004368(Translation initiation factor IF-1)|refseq:WP_010881546.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0097|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:Fn1cU1WIPxvd6jFVDawqLa2LWKU243276 intact-crc:A2782D4858AD3440|rigid:7Ujxt47ud8gH7VFEVyb73fpsJi4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83408 uniprotkb:O83720 intact:EBI-1604685|ensemblbacteria:AAC65377|ensemblbacteria:AGN75587 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83408_trepa(display_long)|uniprotkb:TP_0393(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604688|imex:IM-9152-751 author score:0.097120276 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003488(SMF protein)|refseq:WP_010881841.1|ensemblbacteria:AAC65377(transcript)|ensemblbacteria:AGN75587(transcript)|ensemblbacteria:TP_0393(gene)|ensemblbacteria:TPANIC_0393(gene)|go:"GO:0009294"(DNA mediated transformation) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0393|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:jdJ51G4riKF4cKEzAigpcB5bwN4243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:40D6A64AB58F6EBC|rigid:HmoDtE1bo/4+bjpx7EF870PbHek false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83229 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1604694|ensemblbacteria:AAC65184 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:rl14_trepa(display_long)|uniprotkb:rplN(gene name)|psi-mi:rplN(display_short)|uniprotkb:TP_0199(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604698|imex:IM-9152-752 author score:0.075447287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR005745(Ribosomal protein L14, bacterial-type)|interpro:IPR019972|interpro:IPR000218(Ribosomal protein L14b/L23e)|refseq:WP_010881646.1|ensemblbacteria:AAC65184(transcript)|ensemblbacteria:TP_0199(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036853 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0199|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:jsVp1NKlZ8HhtdYO6SvSIAMVq9U243276 intact-crc:B8630331A831AA51|rigid:/wQNDl/e7Ith10reucB6pcGw3hw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83390 uniprotkb:O83720 intact:EBI-1604708|ensemblbacteria:AAC65380 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y375_trepa(display_long)|uniprotkb:TP_0375(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604704|imex:IM-9152-753 author score:0.075447287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65380(transcript)|ensemblbacteria:TP_0375(gene) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0375|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:C1JjiUEiJ3FW7umk5PAUhH0kdTc243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:B777B4EDEF8300D7|rigid:Lgaqlro4y+7j6h1qlgQN6vSEhr8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83423 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1604717|ensemblbacteria:AAC65396|ensemblbacteria:AGN75602 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83423_trepa(display_long)|uniprotkb:TP_0408(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604713|imex:IM-9152-754 author score:0.075447287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010881856.1|ensemblbacteria:AAC65396(transcript)|ensemblbacteria:AGN75602(transcript)|ensemblbacteria:TP_0408(gene)|ensemblbacteria:TPANIC_0408(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0408|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:8u26NfdyuC69OlOcBNG4Rt9noZU243276 intact-crc:D52B9C5A6342E122|rigid:Yp2GemVW72dpAexc9wE6L7yyVUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83579 uniprotkb:O83720 intact:EBI-1604727|ensemblbacteria:AAC65543|ensemblbacteria:AGN75756 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83579_trepa(display_long)|uniprotkb:TP_0569(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604723|imex:IM-9152-755 author score:0.075447287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000587(Creatinase)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR032416|interpro:IPR033740|refseq:WP_010882016.1|ensemblbacteria:AAC65543(transcript)|ensemblbacteria:AGN75756(transcript)|ensemblbacteria:TP_0569(gene)|ensemblbacteria:TPANIC_0569(gene)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR029149|interpro:IPR036005 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0569|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:E9apHjTGtCF4nAmStRRgKfSEaOE243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:30D01E3958A8E47C|rigid:dUX3v/0Uti3Tl1v7oildQ7eLa6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83616 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1604495|ensemblbacteria:AAC65583 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y607_trepa(display_long)|uniprotkb:TP_0607(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604732|imex:IM-9152-756 author score:0.075447287 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65583(transcript)|ensemblbacteria:TP_0607(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0607|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:Wlw4mclHzfDfJRUUN5S/xvRR41k243276 intact-crc:53C8D8782A7DDF78|rigid:LGFfWskmqq5hzA3EpUhYGRx1v3E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83117 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1603937|ensemblbacteria:AAC65073|ensemblbacteria:AGN75297 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83117_trepa(display_long)|uniprotkb:TP_0078(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604738|imex:IM-9152-757 author score:0.073590644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR000653(DegT/DnrJ/EryC1/StrS aminotransferase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:WP_010881527.1|ensemblbacteria:AAC65073(transcript)|ensemblbacteria:AGN75297(transcript)|ensemblbacteria:TP_0078(gene)|ensemblbacteria:TPANIC_0078(gene)|go:"GO:0003824"(catalytic activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0078|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:dgs5VaBoQFLr25HA4x1ZHP0Mvlw243276 intact-crc:ECEA7265B0EC5750|rigid:pqzjyRGkAvU6C9m2bHjdYMwQi6c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83151 uniprotkb:O83720 intact:EBI-1590645|ensemblbacteria:AAC65102 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:hflk_trepa(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:TP_0113(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604744|imex:IM-9152-758 author score:0.073590644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|ensemblbacteria:AAC65102(transcript)|ensemblbacteria:TP_0113(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881562.1|interpro:IPR036013 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0113|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qyf2DLEImKw76cyCTbyhQtIKMhg243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:02E6F56E264C72F2|rigid:7cbVzGf4Gellj3GCIdGAZf0nxMw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66075 uniprotkb:O83720 intact:EBI-1593152|ensemblbacteria:AAC65244 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:rl31_trepa(display_long)|uniprotkb:rpmE(gene name)|psi-mi:rpmE(display_short)|uniprotkb:TP_0255(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604750|imex:IM-9152-759 author score:0.073590644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034704|interpro:IPR002150(Ribosomal protein L31)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|ensemblbacteria:TP_0255(gene)|ensemblbacteria:AAC65244(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0046872"(metal ion binding)|refseq:WP_010881704.1|interpro:IPR027491|interpro:IPR042105 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0255|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Plc17X4IfA156+SzigoLrjmKWk4243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:0122AA1EED0E63D6|rigid:lRIefjIFw1Q4YAelqnF80NrynhY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83378 uniprotkb:O83720 intact:EBI-1601823|ensemblbacteria:AAC65354 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y359_trepa(display_long)|uniprotkb:TP_0359(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604756|imex:IM-9152-760 author score:0.073590644 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032585|refseq:WP_010881807.1|ensemblbacteria:AAC65354(transcript)|ensemblbacteria:TP_0359(gene) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0359|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZNBm/twUcDj1nIzNnnstFw6rU4c243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:2A68D49A237DDB40|rigid:YIySt0hAlZCaQkK7PHP1IwM0NMQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83361 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198979|intact:EBI-1584166|ensemblbacteria:AAC65326 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:murc_trepa(display_long)|uniprotkb:murC(gene name)|psi-mi:murC(display_short)|uniprotkb:TP_0341(locus name)|uniprotkb:UDP-N-acetylmuramoyl-L-alanine synthetase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604768|imex:IM-9152-762 author score:0.072006542 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR004101(Mur ligase, C-terminal)|interpro:IPR013221(Mur ligase, central)|interpro:IPR000713(Mur ligase, N-terminal)|interpro:IPR005758(UDP-N-acetylmuramate-alanine ligase)|refseq:WP_010881789.1|ensemblbacteria:AAC65326(transcript)|ensemblbacteria:TP_0341(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008763"(UDP-N-acetylmuramate-L-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR036565|interpro:IPR036615 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0341|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ugoM3X6xQbDCFLT4G03V66aSITg243276 intact-crc:7C738B08C891280F|rigid:DdlIGdFR2yj6+unO2Bk0mt/+aYM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83931 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1581886|ensemblbacteria:AAC65920|ensemblbacteria:AGN76130 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83931_trepa(display_long)|uniprotkb:TP_0965(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604762|imex:IM-9152-761 author score:0.072100308 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR032317|ensemblbacteria:AAC65920(transcript)|ensemblbacteria:AGN76130(transcript)|ensemblbacteria:TP_0965(gene)|ensemblbacteria:TPANIC_0965(gene)|refseq:WP_010882409.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0965|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:KMW7R6aaSjjRTuHpclgPtj3uoQs243276 intact-crc:DE2D61DD24CA5CA9|rigid:ayGJ63iBA6R56USNK95udKonfgs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O30405 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198903|intact:EBI-1588248|ensemblbacteria:AAC65246 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:glpq_trepa(display_long)|uniprotkb:glpQ(gene name)|psi-mi:glpQ(display_short)|uniprotkb:glp(gene name synonym)|uniprotkb:TP_0257(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604774|imex:IM-9152-763 author score:0.071776142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010881706.1|interpro:IPR017946|interpro:IPR030395|ensemblbacteria:AAC65246(transcript)|ensemblbacteria:TP_0257(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008889"(glycerophosphodiester phosphodiesterase activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0257|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:cOoFtwqIopb3hvTptL8uBHpkpXw243276 intact-crc:EEB335E927A3396D|rigid:V4W1+Fgb9cpOKLmAdd1kzKUcjls false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83563 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1598364|ensemblbacteria:AAC65538 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y552_trepa(display_long)|uniprotkb:TP_0552(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604780|imex:IM-9152-764 author score:0.071776142 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010881999.1|ensemblbacteria:AAC65538(transcript)|ensemblbacteria:TP_0552(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0552|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:xZWaVKS9sO7lvlFzlBTsUvHMe+o243276 intact-crc:9CBA2303E22C799A|rigid:akODTFXOJ8Otgo3O4wHgoj5XCvs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83427 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1593612|ensemblbacteria:AAC65400|ensemblbacteria:AGN75607 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83427_trepa(display_long)|uniprotkb:TP_0412(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604786|imex:IM-9152-765 author score:0.070003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR021694|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|ensemblbacteria:AAC65400(transcript)|ensemblbacteria:AGN75607(transcript)|ensemblbacteria:TP_0412(gene)|ensemblbacteria:TPANIC_0412(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0032422"(purine-rich negative regulatory element binding)|refseq:WP_010881860.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0412|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:Onu1Iqy65I45pCnfwR8zBgYHZBg243276 intact-crc:C3D675C0047004C1|rigid:L+O51hKesZY0NEty4cvAE420Y74 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83354 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1585574|ensemblbacteria:AAC65321|ensemblbacteria:AGN75532 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83354_trepa(display_long)|uniprotkb:TP_0334(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604792|imex:IM-9152-766 author score:0.068270439 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|ensemblbacteria:AAC65321(transcript)|ensemblbacteria:AGN75532(transcript)|ensemblbacteria:TP_0334(gene)|ensemblbacteria:TPANIC_0334(gene)|go:"GO:0003677"(DNA binding)|refseq:WP_010881782.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0334|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:6DTfWAYClpSiRhhJB12fBKycHkA243276 intact-crc:2AA2411FADA77A72|rigid:+DWjM9302R0S0iSI4ulr6LqcxVA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83457 uniprotkb:O83720 intact:EBI-1198415|intact:EBI-1581959|ensemblbacteria:AAC65430|ensemblbacteria:AGN75636 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83457_trepa(display_long)|uniprotkb:TP_0443(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604804|imex:IM-9152-768 author score:0.066577689 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881891.1|ensemblbacteria:AAC65430(transcript)|ensemblbacteria:AGN75636(transcript)|ensemblbacteria:TP_0443(gene)|ensemblbacteria:TPANIC_0443(gene) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0443|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:cq2lCalN8njtrFwbaBmJAPYbRe8243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:2A50E20FFE777FC3|rigid:uv19G6IEPvKzoBkkypjGLToYmyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83946 uniprotkb:O83720 intact:EBI-1198886|intact:EBI-1583347|ensemblbacteria:AAC65936|ensemblbacteria:AGN76145 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83946_trepa(display_long)|uniprotkb:TP_0981(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604798|imex:IM-9152-767 author score:0.068270439 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029016|interpro:IPR000160(GGDEF)|interpro:IPR029787|refseq:WP_010882425.1|ensemblbacteria:AAC65936(transcript)|ensemblbacteria:AGN76145(transcript)|ensemblbacteria:TP_0981(gene)|ensemblbacteria:TPANIC_0981(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR043128 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0981|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:a68rblJnY4Du2P0aODT2XwjHKgM243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:5360369885487B63|rigid:JBmgpktuq6wn4YFm+iYZQ0eZzzo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O66106 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1583195|ensemblbacteria:AAC65903 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:rsmg_trepa(display_long)|uniprotkb:rsmG(gene name)|psi-mi:rsmG(display_short)|uniprotkb:gidB(gene name synonym)|uniprotkb:16S rRNA 7-methylguanosine methyltransferase(gene name synonym)|uniprotkb:Glucose-inhibited division protein B(gene name synonym)|uniprotkb:TP_0946(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604816|imex:IM-9152-770 author score:0.06416674 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65903(transcript)|ensemblbacteria:TP_0946(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0070043"("rRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR003682(Glucose inhibited division protein)|refseq:WP_010882389.1|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0946|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:f6qBFTfAfwRYdXHuUjXvIk4MO2o243276 intact-crc:089D9A532B4BAD79|rigid:12RaQkebAczbrZNVR8vigkhSmG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83478 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604810|imex:IM-9152-769 author score:0.064923986 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0465|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 intact-crc:32C7F86863CF4995|rigid:Gls50b1dATZMQKlZcbsuhM1g9NM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83373 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1582513|ensemblbacteria:AAC65341 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:kthy_trepa(display_long)|uniprotkb:tmk(gene name)|psi-mi:tmk(display_short)|uniprotkb:dTMP kinase(gene name synonym)|uniprotkb:TP_0354(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604822|imex:IM-9152-771 author score:0.063308572 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR018095|interpro:IPR018094|ensemblbacteria:AAC65341(transcript)|ensemblbacteria:TP_0354(gene)|go:"GO:0004798"(thymidylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006233"(dTDP biosynthetic process)|go:"GO:0006235"(dTTP biosynthetic process)|refseq:WP_010881802.1|interpro:IPR027417|interpro:IPR039430 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0354|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:3ZWudU4gyWn8zGVOFwof++FGCCU243276 intact-crc:35122E3BA3F0F6EF|rigid:KXGR94MehmgD4WtDYBpzXzP7fOo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83962 uniprotkb:O83720 intact:EBI-1592165|ensemblbacteria:AAC26585 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83962_trepa(display_long)|uniprotkb:TP_0997(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604828|imex:IM-9152-772 author score:0.063308572 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004634(Peptidase S49, protease IV)|interpro:IPR002142(Peptidase S49)|ensemblbacteria:AAC26585(transcript)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|ensemblbacteria:TP_0997(gene)|interpro:IPR029045|refseq:WP_010882441.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0997|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:p1nUuiQgfDUABShiOfzpnXyTHpw243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:5B4BFCF812909EA0|rigid:wDR/K3h1PS+TkjWiDlTFhmPD6L8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83275 uniprotkb:O83720 intact:EBI-1582141|ensemblbacteria:AAC65234|ensemblbacteria:AGN75459 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83275_trepa(display_long)|uniprotkb:TP_0247(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604840|imex:IM-9152-774 author score:0.060913602 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012854(Copper amine oxidase-like, N-terminal)|interpro:IPR002508(Cell wall hydrolase/autolysin, catalytic)|ensemblbacteria:AAC65234(transcript)|ensemblbacteria:AGN75459(transcript)|ensemblbacteria:TP_0247(gene)|ensemblbacteria:TPANIC_0247(gene)|go:"GO:0008745"(N-acetylmuramoyl-L-alanine amidase activity)|go:"GO:0009253"(peptidoglycan catabolic process)|refseq:WP_010881695.1|interpro:IPR036582 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0247|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CQCRiL+OJbjQnuKgSbmW+u3Xetk243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:6B58714B92E2DA61|rigid:L+Y7kxLg2VnZ1jiLFQm3eYPBjRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83310 uniprotkb:O83720 intact:EBI-1588258|ensemblbacteria:AAC65268 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83310_trepa(display_long)|uniprotkb:TP_0286(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604834|imex:IM-9152-773 author score:0.061730699 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65268(transcript)|ensemblbacteria:TP_0286(gene) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0286|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:mGA+Jl7wtJoPe9D4Fo/SFJ9DmmU243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:B91C5745D3CFFB1C|rigid:4mY665zcwyYDZHFHG2DcxplX+hc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83752 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1199016|intact:EBI-1582753|ensemblbacteria:AAC65740|ensemblbacteria:AGN75946 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83752_trepa(display_long)|uniprotkb:TP_0773(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604846|imex:IM-9152-775 author score:0.058316654 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|ensemblbacteria:AAC65740(transcript)|ensemblbacteria:AGN75946(transcript)|ensemblbacteria:TP_0773(gene)|ensemblbacteria:TPANIC_0773(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|interpro:IPR036034 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0773|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:R5Jo4EgPW1mHrxhjP03wwzi16Sc243276 intact-crc:2F15CA0B932DC17B|rigid:Z3IuxxsGp7jYr18q2M4KDrhi2gg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83634 uniprotkb:O83720 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604852|imex:IM-9152-776 author score:0.057214951 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0626|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:216721A341F5ABC4|rigid:cnyktes0RoPdMxkh0nuVxnqnqbw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83702 uniprotkb:O83720 intact:EBI-1584881|ensemblbacteria:AAC65672|ensemblbacteria:AGN75879 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83702_trepa(display_long)|uniprotkb:TP_0704(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604858|imex:IM-9152-777 author score:0.057214951 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001667(Phosphoesterase, RecJ-like)|interpro:IPR038763|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR004610(Bacterial RecJ exonuclease)|ensemblbacteria:AAC65672(transcript)|ensemblbacteria:AGN75879(transcript)|ensemblbacteria:TP_0704(gene)|ensemblbacteria:TPANIC_0704(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|refseq:WP_010882149.1|interpro:IPR041122 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0704|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LWNq+ih7RLa5qPu0glrhbmCCWTc243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:3700FEB0E92B7F2C|rigid:/gVT9xM88qTU4pEPWVRElaNuoMM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83119 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1584207|ensemblbacteria:AAC65075|ensemblbacteria:AGN75299 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83119_trepa(display_long)|uniprotkb:TP_0080(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604864|imex:IM-9152-778 author score:0.055779908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensemblbacteria:AAC65075(transcript)|ensemblbacteria:AGN75299(transcript)|ensemblbacteria:TP_0080(gene)|ensemblbacteria:TPANIC_0080(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|refseq:WP_010881529.1|interpro:IPR036010|interpro:IPR036884 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0080|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:7VK0Pmvw0df2M7WXIJl0pEsU5DA243276 intact-crc:5C082182D01F33CE|rigid:/T8EJ+591xby9C6RLQXUOC7YJLs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83261 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198409|intact:EBI-1581973|ensemblbacteria:AAC65221|ensemblbacteria:AGN75445 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83261_trepa(display_long)|uniprotkb:TP_0233(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604870|imex:IM-9152-779 author score:0.055779908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR003658(Anti-sigma factor antagonist)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|refseq:WP_010881681.1|ensemblbacteria:AAC65221(transcript)|ensemblbacteria:AGN75445(transcript)|ensemblbacteria:TP_0233(gene)|ensemblbacteria:TPANIC_0233(gene)|go:"GO:0043856"(anti-sigma factor antagonist activity)|interpro:IPR036513 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0233|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:nm93BPJDsE07g5Ok4U9T4tUxxFw243276 intact-crc:3BDD53E8DC37BD44|rigid:vr2S/3vn6A/C0shx8Uje/8skfbs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83986 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1585764|ensemblbacteria:AAC65974 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:recx_trepa(display_long)|uniprotkb:TP_1023(locus name)|uniprotkb:recX(gene name)|psi-mi:recX(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604876|imex:IM-9152-780 author score:0.055779908 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR003783(Regulatory protein RecX)|ensemblbacteria:AAC65974(transcript)|ensemblbacteria:TP_1023(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_1023|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ARvQQ5ZuZM8v+Y8yr5qnjsoIC6I243276 intact-crc:365E4371FC6E3D1B|rigid:aDbhvdvDAqAISz9lPqIKWQgU26Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83227 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198926|intact:EBI-1582211|ensemblbacteria:AAC65182 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:rl29_trepa(display_long)|uniprotkb:rpmC(gene name)|psi-mi:rpmC(display_short)|uniprotkb:TP_0197(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604888|imex:IM-9152-782 author score:0.053010877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR001854(Ribosomal protein L29)|refseq:WP_010881644.1|ensemblbacteria:AAC65182(transcript)|ensemblbacteria:TP_0197(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR036049 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0197|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:FWT3x8igNfoxF5Ou6BvVqHlDew0243276 intact-crc:8A808FA99F13F2E8|rigid:C35+qz9UKU4lmFStxeC/CDD3sZw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83133 uniprotkb:O83720 intact:EBI-1585148|ensemblbacteria:AAC65099 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y095_trepa(display_long)|uniprotkb:TP_0095(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604882|imex:IM-9152-781 author score:0.053010877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65099(transcript)|ensemblbacteria:TP_0095(gene)|refseq:WP_010881544.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0095|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1xh+BCJcJjIJtqfWLDMEYx664N4243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:3BE3AC8C000FAE8B|rigid:sAeTyJNCKFJ0bmkMMil0eCTWj8g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83913 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198847|intact:EBI-1582190|ensemblbacteria:AAC65896|ensemblbacteria:AGN76107 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83913_trepa(display_long)|uniprotkb:TP_0943(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604894|imex:IM-9152-783 author score:0.053010877 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR003713(Flagellar protein FliS)|refseq:WP_010882386.1|ensemblbacteria:AAC65896(transcript)|ensemblbacteria:AGN76107(transcript)|ensemblbacteria:TP_0943(gene)|ensemblbacteria:TPANIC_0943(gene)|go:"GO:0005829"(cytosol)|go:"GO:0044780"(bacterial-type flagellum assembly)|interpro:IPR036584 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0943|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:l9iRYXKzhpKiqXh5PW2pisAgKnc243276 intact-crc:9C8F75A51EF85A5E|rigid:CP5GHzqL5gMuoaPMpTy4TB0jBMI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83068 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198957|intact:EBI-1585277|ensemblbacteria:AAC65018|ensemblbacteria:AGN75245 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83068_trepa(display_long)|uniprotkb:TP_0024(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604900|imex:IM-9152-784 author score:0.051675499 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR006037(Regulator of K+ conductance, C-terminal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|refseq:WP_010881473.1|ensemblbacteria:AAC65018(transcript)|ensemblbacteria:AGN75245(transcript)|ensemblbacteria:TP_0024(gene)|ensemblbacteria:TPANIC_0024(gene)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|interpro:IPR036291|interpro:IPR036721 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0024|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:XTC1dWjqOYr9OwoU3I+WVPGtDaQ243276 intact-crc:4D968B948FF591A5|rigid:lNFgrHEhnMvtfRc5oa0kCkKJk+Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83542 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198334|intact:EBI-1583423|ensemblbacteria:AAC65517|ensemblbacteria:AGN75718 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83542_trepa(display_long)|uniprotkb:TP_0530(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604912|imex:IM-9152-786 author score:0.047857794 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010881978.1|ensemblbacteria:AAC65517(transcript)|ensemblbacteria:AGN75718(transcript)|ensemblbacteria:TP_0530(gene)|ensemblbacteria:TPANIC_0530(gene)|interpro:IPR038495 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0530|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:W2+QT0Abac3/Ka/hfeDM4hNhEaA243276 intact-crc:66C61249F2904EE6|rigid:kWe1o+dxx6ybWT1BQiW+pZd3f7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83106 uniprotkb:O83720 intact:EBI-1582491|ensemblbacteria:AAC65060 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83106_trepa(display_long)|uniprotkb:TP_0067(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604906|imex:IM-9152-785 author score:0.047857794 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblbacteria:AAC65060(transcript)|ensemblbacteria:TP_0067(gene)|refseq:WP_010881516.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0067|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:CSBsP0t0Z059RlRSsxcyiPXYsRs243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:16F5AE649D155BA1|rigid:QvVjkqlgNFQDYJCvAdZ68kPu1L8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O66107 uniprotkb:O83720 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604924|imex:IM-9152-788 author score:0.045463097 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0945|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:ECEE705AB36DA9CB|rigid:zlDL6yWxJZ2P3peMux4mSV0ZNjg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83738 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1199001|intact:EBI-1583854|ensemblbacteria:AAC65724 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:def_trepa(display_long)|uniprotkb:def(gene name)|psi-mi:def(display_short)|uniprotkb:TP_0757(locus name)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604918|imex:IM-9152-787 author score:0.045547577 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR023635|refseq:WP_010882202.1|ensemblbacteria:AAC65724(transcript)|ensemblbacteria:TP_0757(gene)|go:"GO:0006412"(translation)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR036821 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0757|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:mjvujgH4AwfUgB/qRCDVUIFB0Q0243276 intact-crc:3B2282B183078B67|rigid:0AEJz7J1MXCeMnCBa43qdApPMBc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83596 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1589035|ensemblbacteria:AAC65569 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y587_trepa(display_long)|uniprotkb:TP_0587(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604930|imex:IM-9152-789 author score:0.043182791 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65569(transcript)|ensemblbacteria:TP_0587(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0587|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ZcZm82Vj1HIRi06dv1sfQ7sDF98243276 intact-crc:9AE8444DC8966342|rigid:0r90OQGIJrAdaLwQJMxGKW2V99E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83565 uniprotkb:O83720 intact:EBI-1198823|intact:EBI-1583040|ensemblbacteria:AAC26558|ensemblbacteria:AGN75741 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83565_trepa(display_long)|uniprotkb:TP_0554(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604936|imex:IM-9152-790 author score:0.042223412 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023214|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|ensemblbacteria:AAC26558(transcript)|ensemblbacteria:AGN75741(transcript)|ensemblbacteria:TP_0554(gene)|ensemblbacteria:TPANIC_0554(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR036412|interpro:IPR041492 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0554|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:hWP3cAGV33vY50Xe0XIUNUc/svI243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:0E1B86AEFBF91636|rigid:uk1qQGP2anG9dABC/1YZxn/B7sY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83627 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1584236|ensemblbacteria:AAC65601 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y618_trepa(display_long)|uniprotkb:TP_0618(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604942|imex:IM-9152-791 author score:0.042083987 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR024471|ensemblbacteria:AAC65601(transcript)|ensemblbacteria:TP_0618(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0618|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:jyoxWyXwRferBfrLhvAZeyQQrWk243276 intact-crc:E10C8C289C1EF95E|rigid:gr5+H/ijr1zUzhcCrzpqhdFgzCI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83412 uniprotkb:O83720 intact:EBI-1198574|intact:EBI-1582849|ensemblbacteria:AAC65385|ensemblbacteria:AGN75591 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83412_trepa(display_long)|uniprotkb:TP_0397(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604948|imex:IM-9152-792 author score:0.041011945 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR006299(Flagellar basal-body rod protein FlgC)|ensemblbacteria:AAC65385(transcript)|ensemblbacteria:AGN75591(transcript)|ensemblbacteria:TP_0397(gene)|ensemblbacteria:TPANIC_0397(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010881845.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0397|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:FX4iQE6nwOAw+sTSls0M+JZ/TBw243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:4CB96F2A539A6E96|rigid:+OJO+SXnz6s5DAoE79Dw2IOHFDg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83459 uniprotkb:O83720 intact:EBI-1587921|ensemblbacteria:AGN75638|ensemblbacteria:AAC65432 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83459_trepa(display_long)|uniprotkb:TP_0445(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604954|imex:IM-9152-793 author score:0.0360328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002818(ThiJ/PfpI)|ensemblbacteria:AAC65432(transcript)|ensemblbacteria:AGN75638(transcript)|ensemblbacteria:TP_0445(gene)|ensemblbacteria:TPANIC_0445(gene)|refseq:WP_010881893.1|interpro:IPR029062 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0445|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:/PmnlosOhKXVrqXvmJyxS2Osdl4243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:E08330DFF783FF01|rigid:K21VbmSFL19eWlL18jbVbF/HE7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83670 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198989|intact:EBI-1584338|ensemblbacteria:AAC65637|ensemblbacteria:AGN75842 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83670_trepa(display_long)|uniprotkb:TP_0664(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604966|imex:IM-9152-795 author score:0.032473528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR006714(Flagellar filament outer layer protein FlaA)|refseq:WP_010882109.1|ensemblbacteria:AAC65637(transcript)|ensemblbacteria:AGN75842(transcript)|ensemblbacteria:TP_0664(gene)|ensemblbacteria:TPANIC_0664(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0664|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:4VBhXYG9GKUWCpFXb00ADOUJJo4243276 intact-crc:E8A758B8BD5F67B3|rigid:PZBO5jVEDMIwiu4MxTxe102M9rY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83532 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1584241|ensemblbacteria:AAC65507|ensemblbacteria:AGN75708 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83532_trepa(display_long)|uniprotkb:TP_0519(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604960|imex:IM-9152-794 author score:0.0360328 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011006(CheY-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR002197(Helix-turn-helix, Fis-type)|interpro:IPR002078(RNA polymerase sigma factor 54, interaction)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR025662|interpro:IPR025943|interpro:IPR025944|ensemblbacteria:AAC65507(transcript)|ensemblbacteria:AGN75708(transcript)|ensemblbacteria:TP_0519(gene)|ensemblbacteria:TPANIC_0519(gene)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043565"(sequence-specific DNA binding)|refseq:WP_010881968.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0519|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:xCsuuCy2mq7qxAm8S9lzVnj5hww243276 intact-crc:526E7CF93EEF60F1|rigid:ofk9aHWjaiMvsFFNPfigoOujT28 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83805 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198464|intact:EBI-1581732|ensemblbacteria:AAC65802 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y833_trepa(display_long)|uniprotkb:TP_0833(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604972|imex:IM-9152-796 author score:0.032473528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 refseq:WP_010882277.1|ensemblbacteria:AAC65802(transcript)|ensemblbacteria:TP_0833(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0833|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ZzTzYxa4xxhTQfi6BmhIJt4dIRI243276 intact-crc:7D6F0DF5C6DE3D4D|rigid:3z01jSNybtdvYgLdpmrH0bURxHk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83970 uniprotkb:O83720 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604978|imex:IM-9152-797 author score:0.025000472 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_1005|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:70149E89AA24AC6C|rigid:AuH+gSV09tRTsSHM+pcMTYyFd48 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83982 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1582649|ensemblbacteria:AAC65969 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:gatc_trepa(display_long)|uniprotkb:gatC(gene name)|psi-mi:gatC(display_short)|uniprotkb:TP_1019(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604984|imex:IM-9152-798 author score:0.024964708 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65969(transcript)|ensemblbacteria:TP_1019(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0050566"("asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_1019|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:9/qqO6eAKe78oz6x2UiuFRyh/HY243276 intact-crc:5478138D3467BDDF|rigid:HBzcMpRqbA+u/z79zLsoqsdCdpA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83709 uniprotkb:O83720 intact:EBI-1198665|intact:EBI-1584256|ensemblbacteria:AAC65677 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y711_trepa(display_long)|uniprotkb:TP_0711(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604990|imex:IM-9152-799 author score:0.02372101 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882156.1|ensemblbacteria:AAC65677(transcript)|ensemblbacteria:TP_0711(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0711|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Pwv3UCwcpePrKPq9Pscaa5yrgNM243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:9D6BDF11CDB5282A|rigid:gcH9Uc0R0QzYG5N/eBWiFDVjVRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83463 uniprotkb:O83720 intact:EBI-1582872|ensemblbacteria:AAC65437 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y449_trepa(display_long)|uniprotkb:TP_0449(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1604996|imex:IM-9152-800 author score:0.020795587 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|ensemblbacteria:AAC65437(transcript)|ensemblbacteria:TP_0449(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010881897.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0449|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:bWyAu5xKIUn1fs78TU3yTvxRM1Y243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:8663843E36084852|rigid:xXfmP0dBtanXXt3Yf84I4pjCgcs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83969 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1581850|ensemblbacteria:AAC65952 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605008|imex:IM-9152-802 author score:0.014380939 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_1004|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 intact-crc:4DFDAAD89D87C666|rigid:Y+G4duQ1YcHWZgNx8NpXai0BA+w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83305 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1582887|ensemblbacteria:AAC65278 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y281_trepa(display_long)|uniprotkb:TP_0281(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605002|imex:IM-9152-801 author score:0.014745067 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65278(transcript)|ensemblbacteria:TP_0281(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0281|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:sdpBjJSXQh+mZkAr2p8SuQt6Dsw243276 intact-crc:175424CC91DCB8DC|rigid:OKjlyQdKcPqoGUj836UP2EndQDA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83531 uniprotkb:O83720 intact:EBI-1198626|intact:EBI-1584373|ensemblbacteria:AAC65506|ensemblbacteria:AGN75707 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83531_trepa(display_long)|uniprotkb:TP_0518(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605014|imex:IM-9152-803 author score:0.012573301 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006282(Thiamin pyrophosphokinase)|interpro:IPR007371(Thiamin pyrophosphokinase, catalytic region)|refseq:WP_010881967.1|ensemblbacteria:AAC65506(transcript)|ensemblbacteria:AGN75707(transcript)|ensemblbacteria:TP_0518(gene)|ensemblbacteria:TPANIC_0518(gene)|go:"GO:0004788"(thiamine diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|interpro:IPR036371|interpro:IPR036759 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0518|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rrGeg33XoqpkKQgWVv6+yO96Yik243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:D50CB517059EFAE2|rigid:Ra8HHBpDRepg58pe36fdMFWSFOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83099 uniprotkb:O83720 intact:EBI-1582052|ensemblbacteria:AAC65055 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:rl9_trepa(display_long)|uniprotkb:rplI(gene name)|psi-mi:rplI(display_short)|uniprotkb:TP_0060(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605020|imex:IM-9152-804 author score:0.010161794 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020594|interpro:IPR020069|interpro:IPR020070|ensemblbacteria:AAC65055(transcript)|ensemblbacteria:TP_0060(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|refseq:WP_010881509.1|interpro:IPR036791|interpro:IPR036935 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0060|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2jje34Ooz7fALUzVaG/qvB3aqEU243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:A2C14F14C7C17B1B|rigid:uU8pwbn/gbcobndyjR511BwbeSo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:P21992 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198854|intact:EBI-1581911|uniprotkb:O83840|ensemblbacteria:AAC65835 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:flab3_trepa(display_long)|uniprotkb:flaB3(gene name)|psi-mi:flaB3(display_short)|uniprotkb:Class B(gene name synonym)|uniprotkb:Flagellar filament 31 kDa core protein(gene name synonym)|uniprotkb:TP_0870(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605026|imex:IM-9152-805 author score:0.009894534 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR001492(Flagellin, N-terminal)|interpro:IPR001029(Flagellin, C-terminal)|refseq:WP_010882313.1|ensemblbacteria:AAC65835(transcript)|ensemblbacteria:TP_0870(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0055040"(periplasmic flagellum)|interpro:IPR042187 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0870|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:FXtCjQP0o+TOyheo9qx+qXUEOw8243276 intact-crc:0B32F52463CC5865|rigid:VKvVcfgBeq396pqnacRy80xpvPM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83927 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1198947|intact:EBI-1581785|ensemblbacteria:AAC65916|ensemblbacteria:AGN76126 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83927_trepa(display_long)|uniprotkb:TP_0961(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605032|imex:IM-9152-806 author score:0.008659154 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR010930(Protein of unknown function DUF1078, C-terminal)|interpro:IPR001444(Flagellar basal body rod protein)|interpro:IPR020013|interpro:IPR012836(Flagellar basal-body rod FlgF)|refseq:WP_010882405.1|interpro:IPR037925|ensemblbacteria:AAC65916(transcript)|ensemblbacteria:AGN76126(transcript)|ensemblbacteria:TP_0961(gene)|ensemblbacteria:TPANIC_0961(gene)|go:"GO:0030694"(bacterial-type flagellum basal body, rod)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0961|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:AjuGthSrs8pLvu0iSBeI0USZmJk243276 intact-crc:FC65E005F39AAE01|rigid:IzwhSeVc07YmrbklWXtu6zp/HzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83877 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605044|imex:IM-9152-808 author score:0.005915875 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0907|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:EC2F2A7357F5DCE7|rigid:I66llsvXyQfGn16NbkUEBQoexpM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83574 uniprotkb:O83720 intact:EBI-1581747|ensemblbacteria:AAC65546|ensemblbacteria:AGN75750 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83574_trepa(display_long)|uniprotkb:TP_0563(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605038|imex:IM-9152-807 author score:0.006808554 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|ensemblbacteria:AAC65546(transcript)|ensemblbacteria:AGN75750(transcript)|ensemblbacteria:TP_0563(gene)|ensemblbacteria:TPANIC_0563(gene)|interpro:IPR036869 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0563|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TyfzWH3/GtejvqaTS283U6Iv5A4243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:53F2D76B2D5E0AEC|rigid:zW12m6X+bb+KghMaPFwnUoeT9t4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83720 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605050|imex:IM-9152-809 author score:0.003579725 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:C791773256D506E0|rigid:x1yUPrdkBIVLHT2qBsG8wfoT7pQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83767 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605056|imex:IM-9152-810 author score:0.002393218 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:1BFD6E4115AB10D3|rigid:srff/FWmSiEEY1QEUt9s27nRm+E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83745 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605062|imex:IM-9152-811 author score:0.001982964 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:89868D9FC85B690F|rigid:YG0gGWqOIK6pIg/pkw+iKGmvdSU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83720 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605068|imex:IM-9152-812 author score:0.000794866 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:F99CBFFA82CF0D0B|rigid:Pr1ccl+GMPdVfFWuisAnzQI4AFI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83720 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586100|ensemblbacteria:AAC65706 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605080|imex:IM-9152-814 author score:0.000140827 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 intact-crc:D754D65EF734B5F0|rigid:jn/PkkRoPikQ5fkRcTV49L+Y87s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83720 uniprotkb:O83954 intact:EBI-1586100|ensemblbacteria:AAC65706 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:iojap_trepa(display_long)|uniprotkb:rsfS(gene name)|psi-mi:rsfS(display_short)|uniprotkb:TP_0738(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605074|imex:IM-9152-813 author score:0.000658426 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004394(Iojap-related protein)|ensemblbacteria:AAC65706(transcript)|ensemblbacteria:TP_0738(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|refseq:WP_010882183.1|interpro:IPR043519 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0738; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IEjy9w6VHz7aWJZGYtQcSPbcH3k243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:8AE3B9DB235EAC74|rigid:OkO8Zp32DZ2R+ID2yoR6L+94uUw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83655 uniprotkb:O83413 intact:EBI-1605086|ensemblbacteria:AAC65622|ensemblbacteria:AGN75829 intact:EBI-1198218|intact:EBI-1582248|ensemblbacteria:AAC65386 psi-mi:o83655_trepa(display_long)|uniprotkb:TP_0649(locus name) psi-mi:flie_trepa(display_long)|uniprotkb:fliE(gene name)|psi-mi:fliE(display_short)|uniprotkb:TP_0398(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605089|imex:IM-9152-946 author score:0.15107692 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005170(Transporter-associated region)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:WP_010882094.1|ensemblbacteria:AAC65622(transcript)|ensemblbacteria:AGN75829(transcript)|ensemblbacteria:TP_0649(gene)|ensemblbacteria:TPANIC_0649(gene)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 interpro:IPR001624(Flagellar hook-basal body complex protein FliE)|refseq:WP_010881846.1|ensemblbacteria:AAC65386(transcript)|ensemblbacteria:TP_0398(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0009425"(bacterial-type flagellum basal body)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0649; PREY protein TP_0398|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rsetDXw6c6MHGj3ZNmqV6eU0ROA243276 rogid:vhmKQif6JhfmDjuSn8V1uq7KGu4243276 intact-crc:7C46BC6B9A461228|rigid:XI0DYgLzB8UmKK4eG8g7u4vnsyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83655 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605086|ensemblbacteria:AAC65622|ensemblbacteria:AGN75829 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83655_trepa(display_long)|uniprotkb:TP_0649(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605095|imex:IM-9152-816 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005170(Transporter-associated region)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:WP_010882094.1|ensemblbacteria:AAC65622(transcript)|ensemblbacteria:AGN75829(transcript)|ensemblbacteria:TP_0649(gene)|ensemblbacteria:TPANIC_0649(gene)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0649; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:rsetDXw6c6MHGj3ZNmqV6eU0ROA243276 intact-crc:4928466D51D5970B|rigid:foKR40/8Ho/xuSBLVPichXhuHtc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83655 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1605086|ensemblbacteria:AAC65622|ensemblbacteria:AGN75829 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83655_trepa(display_long)|uniprotkb:TP_0649(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605101|imex:IM-9152-817 author score:0.029225208 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005170(Transporter-associated region)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:WP_010882094.1|ensemblbacteria:AAC65622(transcript)|ensemblbacteria:AGN75829(transcript)|ensemblbacteria:TP_0649(gene)|ensemblbacteria:TPANIC_0649(gene)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0649; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:rsetDXw6c6MHGj3ZNmqV6eU0ROA243276 intact-crc:B774D686F79F8FAE|rigid:NAAawSIVRgGfVcrMnimijTVB/E0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83655 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605086|ensemblbacteria:AAC65622|ensemblbacteria:AGN75829 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83655_trepa(display_long)|uniprotkb:TP_0649(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605107|imex:IM-9152-818 author score:0.002481187 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005170(Transporter-associated region)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|refseq:WP_010882094.1|ensemblbacteria:AAC65622(transcript)|ensemblbacteria:AGN75829(transcript)|ensemblbacteria:TP_0649(gene)|ensemblbacteria:TPANIC_0649(gene)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0649; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:rsetDXw6c6MHGj3ZNmqV6eU0ROA243276 intact-crc:7657A859C8DB3FDD|rigid:DzQIZm5pbYpZiuAdvSBZydOHvMY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83151 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1590645|ensemblbacteria:AAC65102 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:hflk_trepa(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:TP_0113(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605113|imex:IM-9152-819 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|ensemblbacteria:AAC65102(transcript)|ensemblbacteria:TP_0113(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881562.1|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0113; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:qyf2DLEImKw76cyCTbyhQtIKMhg243276 intact-crc:456A11D63F5420CE|rigid:qwsoRJPmrCRzxRWCBr/gpDrYWL0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83151 uniprotkb:O83745 intact:EBI-1590645|ensemblbacteria:AAC65102 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:hflk_trepa(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:TP_0113(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605119|imex:IM-9152-820 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|ensemblbacteria:AAC65102(transcript)|ensemblbacteria:TP_0113(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881562.1|interpro:IPR036013 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0113; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qyf2DLEImKw76cyCTbyhQtIKMhg243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:2975B15096DF134B|rigid:HkDB6nYWyKWBVckKKKrfFyHv0Go false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83151 uniprotkb:O83958 intact:EBI-1590645|ensemblbacteria:AAC65102 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:hflk_trepa(display_long)|uniprotkb:hflK(gene name)|psi-mi:hflK(display_short)|uniprotkb:TP_0113(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605125|imex:IM-9152-821 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001107(Band 7 protein)|interpro:IPR010201(HflK)|ensemblbacteria:AAC65102(transcript)|ensemblbacteria:TP_0113(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881562.1|interpro:IPR036013 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0113; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:qyf2DLEImKw76cyCTbyhQtIKMhg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:433CE89C68AE4345|rigid:5sVlcj2m9is3PbP1FESvTtevoPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:P96122 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605135|uniprotkb:O83200|ensemblbacteria:AAC65159 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:mtnn_trepa(display_long)|uniprotkb:mtnN(gene name)|psi-mi:mtnN(display_short)|uniprotkb:mtn(gene name synonym)|uniprotkb:5'-methylthioadenosine nucleosidase(gene name synonym)|uniprotkb:S-adenosylhomocysteine nucleosidase(gene name synonym)|uniprotkb:TP_0170(locus name)|uniprotkb:5'-deoxyadenosine nucleosidase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605141|imex:IM-9152-823 author score:0.121080071 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR010049(MTA/SAH nucleosidase)|interpro:IPR000845(Nucleoside phosphorylase)|refseq:WP_010881617.1|ensemblbacteria:AAC65159(transcript)|ensemblbacteria:TP_0170(gene)|go:"GO:0008782"(adenosylhomocysteine nucleosidase activity)|go:"GO:0008930"(methylthioadenosine nucleosidase activity)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR035994 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0170; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:y3+6ugAnhXyd5AoBOIg5BNQ26Wo243276 intact-crc:0FA27F43DE772D11|rigid:iHB6/onMTmA3HRcQqwiE51FAIHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:P96122 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1605135|uniprotkb:O83200|ensemblbacteria:AAC65159 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:mtnn_trepa(display_long)|uniprotkb:mtnN(gene name)|psi-mi:mtnN(display_short)|uniprotkb:mtn(gene name synonym)|uniprotkb:5'-methylthioadenosine nucleosidase(gene name synonym)|uniprotkb:S-adenosylhomocysteine nucleosidase(gene name synonym)|uniprotkb:TP_0170(locus name)|uniprotkb:5'-deoxyadenosine nucleosidase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605131|imex:IM-9152-822 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR010049(MTA/SAH nucleosidase)|interpro:IPR000845(Nucleoside phosphorylase)|refseq:WP_010881617.1|ensemblbacteria:AAC65159(transcript)|ensemblbacteria:TP_0170(gene)|go:"GO:0008782"(adenosylhomocysteine nucleosidase activity)|go:"GO:0008930"(methylthioadenosine nucleosidase activity)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR035994 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0170; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:y3+6ugAnhXyd5AoBOIg5BNQ26Wo243276 intact-crc:9532E73D3DB024EC|rigid:X706+ZwTbLxOFnURqoWy6Q37tGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P96122 uniprotkb:O83958 intact:EBI-1605135|uniprotkb:O83200|ensemblbacteria:AAC65159 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:mtnn_trepa(display_long)|uniprotkb:mtnN(gene name)|psi-mi:mtnN(display_short)|uniprotkb:mtn(gene name synonym)|uniprotkb:5'-methylthioadenosine nucleosidase(gene name synonym)|uniprotkb:S-adenosylhomocysteine nucleosidase(gene name synonym)|uniprotkb:TP_0170(locus name)|uniprotkb:5'-deoxyadenosine nucleosidase(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605147|imex:IM-9152-824 author score:0.00303408 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010049(MTA/SAH nucleosidase)|interpro:IPR000845(Nucleoside phosphorylase)|refseq:WP_010881617.1|ensemblbacteria:AAC65159(transcript)|ensemblbacteria:TP_0170(gene)|go:"GO:0008782"(adenosylhomocysteine nucleosidase activity)|go:"GO:0008930"(methylthioadenosine nucleosidase activity)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|interpro:IPR035994 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0170; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:y3+6ugAnhXyd5AoBOIg5BNQ26Wo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D2D7F8A22E2B9D93|rigid:S+MgfbVz77e3JrdkNVtY5LKsVxs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83667 uniprotkb:O83634 intact:EBI-1582276|ensemblbacteria:AAC65640 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605153|imex:IM-9152-825 author score:0.148768565 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0626; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:30D1B8EF417D218C|rigid:crBZuTi66pEIOgRSB1pilDwBUOU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83634 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605159|imex:IM-9152-826 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0626; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 intact-crc:C046B69C40DE1540|rigid:y3RedZofymfLqXkyGOwRn/KjpuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83634 uniprotkb:O83954 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605165|imex:IM-9152-827 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0626; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:38F490DC2619A21C|rigid:OaRZ2+3h+sEk55YirRmDG9HzKSg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O67998 uniprotkb:O83667 intact:EBI-1605175|uniprotkb:Q7DFP5|uniprotkb:F7IW75|ensemblbacteria:AGN75647|ensemblbacteria:AAC65443 intact:EBI-1582276|ensemblbacteria:AAC65640 psi-mi:tp453_trepa(display_long)|uniprotkb:30kLP(gene name synonym)|uniprotkb:TPANIC_0453(orf name)|uniprotkb:TP_0453(locus name) psi-mi:y661_trepa(display_long)|uniprotkb:TP_0661(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605171|imex:IM-9152-828 author score:0.141007526 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3K8G|rcsb pdb:3K8H|rcsb pdb:3K8I|rcsb pdb:3K8J|refseq:WP_010881902.1|ensemblbacteria:AAC65443(transcript)|ensemblbacteria:AGN75647(transcript)|ensemblbacteria:TP_0453(gene)|ensemblbacteria:TPANIC_0453(gene)|go:"GO:0009279"(cell outer membrane) ensemblbacteria:AAC65640(transcript)|ensemblbacteria:TP_0661(gene)|refseq:WP_010882106.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0453; PREY protein TP_0661|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OiaCBbls2eeWJkZiNfYp1lySllU243276 rogid:1Eu6rMEkrE22peNFd784nu5byFc243276 intact-crc:C6030E7CAEFD89DD|rigid:JdRWowj6bkOzoKhnbZiGFJzVtwo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O67998 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1605175|uniprotkb:Q7DFP5|uniprotkb:F7IW75|ensemblbacteria:AGN75647|ensemblbacteria:AAC65443 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:tp453_trepa(display_long)|uniprotkb:30kLP(gene name synonym)|uniprotkb:TPANIC_0453(orf name)|uniprotkb:TP_0453(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605181|imex:IM-9152-829 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 rcsb pdb:3K8G|rcsb pdb:3K8H|rcsb pdb:3K8I|rcsb pdb:3K8J|refseq:WP_010881902.1|ensemblbacteria:AAC65443(transcript)|ensemblbacteria:AGN75647(transcript)|ensemblbacteria:TP_0453(gene)|ensemblbacteria:TPANIC_0453(gene)|go:"GO:0009279"(cell outer membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0453; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:OiaCBbls2eeWJkZiNfYp1lySllU243276 intact-crc:01352F8EE9766F45|rigid:U0tJPloNNRjE6Gr8QMwdXWu0LIQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O67998 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605175|uniprotkb:Q7DFP5|uniprotkb:F7IW75|ensemblbacteria:AGN75647|ensemblbacteria:AAC65443 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:tp453_trepa(display_long)|uniprotkb:30kLP(gene name synonym)|uniprotkb:TPANIC_0453(orf name)|uniprotkb:TP_0453(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605187|imex:IM-9152-830 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 rcsb pdb:3K8G|rcsb pdb:3K8H|rcsb pdb:3K8I|rcsb pdb:3K8J|refseq:WP_010881902.1|ensemblbacteria:AAC65443(transcript)|ensemblbacteria:AGN75647(transcript)|ensemblbacteria:TP_0453(gene)|ensemblbacteria:TPANIC_0453(gene)|go:"GO:0009279"(cell outer membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0453; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:OiaCBbls2eeWJkZiNfYp1lySllU243276 intact-crc:8C76FD3679D20AAE|rigid:2CnfjBcvCsaVzzXMIk8TlTJ7aRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O67998 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605175|uniprotkb:Q7DFP5|uniprotkb:F7IW75|ensemblbacteria:AGN75647|ensemblbacteria:AAC65443 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:tp453_trepa(display_long)|uniprotkb:30kLP(gene name synonym)|uniprotkb:TPANIC_0453(orf name)|uniprotkb:TP_0453(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605193|imex:IM-9152-831 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 rcsb pdb:3K8G|rcsb pdb:3K8H|rcsb pdb:3K8I|rcsb pdb:3K8J|refseq:WP_010881902.1|ensemblbacteria:AAC65443(transcript)|ensemblbacteria:AGN75647(transcript)|ensemblbacteria:TP_0453(gene)|ensemblbacteria:TPANIC_0453(gene)|go:"GO:0009279"(cell outer membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0453; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:OiaCBbls2eeWJkZiNfYp1lySllU243276 intact-crc:503E572D69E9E9ED|rigid:y4q7AxuKN2hzcVU6Iyq/VPlX6YQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83879 uniprotkb:O83745 intact:EBI-1587693|ensemblbacteria:AAC65861 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:rl19_trepa(display_long)|uniprotkb:rplS(gene name)|psi-mi:rplS(display_short)|uniprotkb:TP_0909(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605199|imex:IM-9152-832 author score:0.139142794 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001857(Ribosomal protein L19)|interpro:IPR018257|interpro:IPR008991(Translation protein SH3-like)|ensemblbacteria:AAC65861(transcript)|ensemblbacteria:TP_0909(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882352.1|interpro:IPR038657 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0909; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9du6UVWUJ5W1+DJGutXUAQCgWs243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:F39B3C722D2EF4B0|rigid:rJlnmh/kClG3NX7bMk1N0Qdlves false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83879 uniprotkb:O83958 intact:EBI-1587693|ensemblbacteria:AAC65861 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rl19_trepa(display_long)|uniprotkb:rplS(gene name)|psi-mi:rplS(display_short)|uniprotkb:TP_0909(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605205|imex:IM-9152-833 author score:0.003537787 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001857(Ribosomal protein L19)|interpro:IPR018257|interpro:IPR008991(Translation protein SH3-like)|ensemblbacteria:AAC65861(transcript)|ensemblbacteria:TP_0909(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|refseq:WP_010882352.1|interpro:IPR038657 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0909; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:T9du6UVWUJ5W1+DJGutXUAQCgWs243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B7B9DB973FB9A6B7|rigid:gVDwg+zzNacGnUWer8gv9jsQkWQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83112 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605215|ensemblbacteria:AAC65078 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y073_trepa(display_long)|uniprotkb:TP_0073(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605211|imex:IM-9152-834 author score:0.134419528 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR013976(Metal-dependent hydrolase HDOD)|refseq:WP_010881522.1|ensemblbacteria:AAC65078(transcript)|ensemblbacteria:TP_0073(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0073; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:6CPaoyDNP30M8vctwIUD0C1OvrM243276 intact-crc:3C1B36A803F8FD31|rigid:WD/quzYwMSptPJGrS0RaHEIIjfg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83112 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605215|ensemblbacteria:AAC65078 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y073_trepa(display_long)|uniprotkb:TP_0073(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605220|imex:IM-9152-835 author score:0.003716766 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR013976(Metal-dependent hydrolase HDOD)|refseq:WP_010881522.1|ensemblbacteria:AAC65078(transcript)|ensemblbacteria:TP_0073(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0073; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:6CPaoyDNP30M8vctwIUD0C1OvrM243276 intact-crc:501E9BFB9CF2170F|rigid:izXe8PeClih5FPvozZ9mP9O3B9c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83537 uniprotkb:O83745 intact:EBI-1605226|ensemblbacteria:AAC65512 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:efp_trepa(display_long)|uniprotkb:efp(gene name)|psi-mi:efp(display_short)|uniprotkb:TP_0525(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605230|imex:IM-9152-836 author score:0.131104996 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015365(Elongation factor P, C-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR020599|interpro:IPR013185(Translation elongation factor, KOW-like)|interpro:IPR001059(Translation elongation factor P/YeiP, central)|interpro:IPR013852(Translation elongation factor P/YeiP, conserved site)|interpro:IPR011768(Translation elongation factor P)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881973.1|ensemblbacteria:AAC65512(transcript)|ensemblbacteria:TP_0525(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005737"(cytoplasm) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0525; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:pSiMQlVyEGthq0DKoAtVswa1H28243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:B44E169FE3797190|rigid:YtOoDX+w0kOv9FxEiC0sxHlW4Oo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83522 uniprotkb:O83745 intact:EBI-1605236|ensemblbacteria:AAC65497|ensemblbacteria:AGN75698 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83522_trepa(display_long)|uniprotkb:Peroxiredoxin(gene name synonym)|uniprotkb:Thioredoxin peroxidase(gene name synonym)|uniprotkb:TP_0509(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605239|imex:IM-9152-837 author score:0.125170403 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017559(Peroxiredoxin)|refseq:WP_010881958.1|ensemblbacteria:AAC65497(transcript)|ensemblbacteria:AGN75698(transcript)|ensemblbacteria:TP_0509(gene)|ensemblbacteria:TPANIC_0509(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0102039"(alkylhydroperoxide reductase activity)|interpro:IPR036249 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0509; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:n2M1FP5NPKDFpJ5p4mXp1wnPWJQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:DD8D82CD4C242C2C|rigid:ud5Kn/j6VtVoQhBaTm1hS0prxUI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83522 uniprotkb:O83282 intact:EBI-1605236|ensemblbacteria:AAC65497|ensemblbacteria:AGN75698 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83522_trepa(display_long)|uniprotkb:Peroxiredoxin(gene name synonym)|uniprotkb:Thioredoxin peroxidase(gene name synonym)|uniprotkb:TP_0509(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605245|imex:IM-9152-838 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017559(Peroxiredoxin)|refseq:WP_010881958.1|ensemblbacteria:AAC65497(transcript)|ensemblbacteria:AGN75698(transcript)|ensemblbacteria:TP_0509(gene)|ensemblbacteria:TPANIC_0509(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0102039"(alkylhydroperoxide reductase activity)|interpro:IPR036249 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0509; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:n2M1FP5NPKDFpJ5p4mXp1wnPWJQ243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:67C3B8BB78CD9268|rigid:tdU/Sv7aqsAZY9KRPBvbX4msmC4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83679 uniprotkb:O83767 intact:EBI-1600371|ensemblbacteria:AAC26571 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:sye_trepa(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0673(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605257|imex:IM-9152-840 author score:0.110516645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033910|refseq:WP_010882118.1|ensemblbacteria:AAC26571(transcript)|ensemblbacteria:TP_0673(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|interpro:IPR020752 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0673; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:nvqK5EgGT4yJnD2HYec4tPrUj0c243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:CE7B5B8D6FAEB81A|rigid:5RGczVvIqtC+uxp7TfVJpyaZjv0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83349 uniprotkb:O83767 intact:EBI-1600365|ensemblbacteria:AAC65317 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:glya_trepa(display_long)|uniprotkb:glyA(gene name)|psi-mi:glyA(display_short)|uniprotkb:TP_0329(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605251|imex:IM-9152-839 author score:0.116827715 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|ensemblbacteria:AAC65317(transcript)|ensemblbacteria:TP_0329(gene)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|interpro:IPR039429 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0329; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LFMwg5Gy2bjW5KbUHE/f9otRy6M243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:315CA32EE1D54F49|rigid:q3PYTojd9sxzcoIJymmbpc75Kzs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83679 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1600371|ensemblbacteria:AAC26571 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:sye_trepa(display_long)|uniprotkb:gltX(gene name)|psi-mi:gltX(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0673(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605263|imex:IM-9152-841 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR020751|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033910|refseq:WP_010882118.1|ensemblbacteria:AAC26571(transcript)|ensemblbacteria:TP_0673(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|interpro:IPR020752 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0673; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:nvqK5EgGT4yJnD2HYec4tPrUj0c243276 intact-crc:348F93D5A2D560D9|rigid:s3JijBTGJQwtMi8flVYrEY32Odk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83756 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1605273|ensemblbacteria:AAC65750 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y777_trepa(display_long)|uniprotkb:TP_0777(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605269|imex:IM-9152-842 author score:0.110516645 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 refseq:WP_010882222.1|ensemblbacteria:AAC65750(transcript)|ensemblbacteria:TP_0777(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0777; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:LUM9hOI8zsg0TJLgqrE4X+b3gio243276 intact-crc:CB510FBBC90E990D|rigid:SmlQYPYf3aDuvUgb9nBNqfSR3+Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83756 uniprotkb:O83954 intact:EBI-1605273|ensemblbacteria:AAC65750 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y777_trepa(display_long)|uniprotkb:TP_0777(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605278|imex:IM-9152-843 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882222.1|ensemblbacteria:AAC65750(transcript)|ensemblbacteria:TP_0777(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0777; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:LUM9hOI8zsg0TJLgqrE4X+b3gio243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:2ECB2F65C2FEFCBE|rigid:XW9+ADlbEk2F9V/SgAkqWNTif7Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83172 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1605288|ensemblbacteria:AAC65137 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y136_trepa(display_long)|uniprotkb:TP_0136(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605284|imex:IM-9152-844 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65137(transcript)|ensemblbacteria:TP_0136(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0136; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:iwnEjOScvTkF3tuuyuZp41cV2Zs243276 intact-crc:DA9CBBF915F9EFD3|rigid:Q21yvjjB35aslpDFoYGkLq0hBqw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83172 uniprotkb:O83282 intact:EBI-1605288|ensemblbacteria:AAC65137 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y136_trepa(display_long)|uniprotkb:TP_0136(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605293|imex:IM-9152-845 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65137(transcript)|ensemblbacteria:TP_0136(gene)|go:"GO:0005886"(plasma membrane) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0136; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iwnEjOScvTkF3tuuyuZp41cV2Zs243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:09EC61DC34C817DF|rigid:z2jomDK9OONHo+vJ/1d6hsQlRPE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83172 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605288|ensemblbacteria:AAC65137 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y136_trepa(display_long)|uniprotkb:TP_0136(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605299|imex:IM-9152-846 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65137(transcript)|ensemblbacteria:TP_0136(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0136; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:iwnEjOScvTkF3tuuyuZp41cV2Zs243276 intact-crc:3085D69326F95441|rigid:zf9GLa+GbVXq60z1Ta2w2Xudr8M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83478 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605311|imex:IM-9152-848 author score:0.088137857 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0465; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 intact-crc:8D9FA6C633308CB1|rigid:D+EiFsDfRue0Q7YYVkw+4csYuOE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83478 uniprotkb:O83767 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605305|imex:IM-9152-847 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0465; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:0DCF9260FE41672D|rigid:dLE1gFTd1bXjHkFKObVXBJstU5w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83478 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198613|intact:EBI-1588422|ensemblbacteria:AAC65457 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y465_trepa(display_long)|uniprotkb:TP_0465(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605317|imex:IM-9152-849 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010881914.1|ensemblbacteria:AAC65457(transcript)|ensemblbacteria:TP_0465(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0465; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:ZkXhuCor4mV1NNPhpiCJ06wIZA8243276 intact-crc:E7D6FF0ACD41DCBF|rigid:wsZaVXTVrA0IKGZQ9GlO5fk0rh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83583 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1605323|ensemblbacteria:AAC65550 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:y573_trepa(display_long)|uniprotkb:TP_0573(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605326|imex:IM-9152-850 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 ensemblbacteria:AAC65550(transcript)|ensemblbacteria:TP_0573(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0573; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:VZWqjwVSAoSR+L0C5bHkRtOkNGw243276 intact-crc:A88C412AD13B6AAA|rigid:rFqmA+xjqoY5CJ7b7LmxbKRG+iQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83583 uniprotkb:O83282 intact:EBI-1605323|ensemblbacteria:AAC65550 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:y573_trepa(display_long)|uniprotkb:TP_0573(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605332|imex:IM-9152-851 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65550(transcript)|ensemblbacteria:TP_0573(gene) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0573; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VZWqjwVSAoSR+L0C5bHkRtOkNGw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:9F839B612158A574|rigid:IFRmX1JlDXXGLUuQQGbVPu7s/Yw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83583 uniprotkb:O83958 intact:EBI-1605323|ensemblbacteria:AAC65550 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y573_trepa(display_long)|uniprotkb:TP_0573(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605338|imex:IM-9152-852 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65550(transcript)|ensemblbacteria:TP_0573(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0573; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:VZWqjwVSAoSR+L0C5bHkRtOkNGw243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:42952C40E23BD138|rigid:OFC9WLUVaQvr5ySDR/vPVvIFAUo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83793 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1584868|ensemblbacteria:AAC65788 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:y818_trepa(display_long)|uniprotkb:TP_0818(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605350|imex:IM-9152-854 author score:0.037256849 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 ensemblbacteria:AAC65788(transcript)|ensemblbacteria:TP_0818(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0818; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:QnxKmMr04H37/A461aRYWlKKgdE243276 intact-crc:DD97AAD6550C3BDF|rigid:dAH3wLGC6q2FwwshbokEHuTyfQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83793 uniprotkb:O83767 intact:EBI-1584868|ensemblbacteria:AAC65788 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:y818_trepa(display_long)|uniprotkb:TP_0818(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605344|imex:IM-9152-853 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65788(transcript)|ensemblbacteria:TP_0818(gene) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0818; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:QnxKmMr04H37/A461aRYWlKKgdE243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:AF843D3C574DDF19|rigid:Z9+ed9CmO1depTiUL3ZLS30WKAM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83803 uniprotkb:O83767 intact:EBI-1587743|ensemblbacteria:AAC65797 intact:EBI-1582289|ensemblbacteria:AAC65763 psi-mi:syr_trepa(display_long)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0831(locus name) psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605362|imex:IM-9152-856 author score:0.104506158 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65797(transcript)|ensemblbacteria:TP_0831(gene)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|refseq:WP_010882275.1|interpro:IPR035684|interpro:IPR036695 ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0831; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aln69UFLKLBAAUJHdtg7+v6YzXE243276 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 intact-crc:4ABE755AF91B1E15|rigid:eMKuubWIXfOqaVmF9M7ySmhJt5A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83803 uniprotkb:O83954 intact:EBI-1587743|ensemblbacteria:AAC65797 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:syr_trepa(display_long)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0831(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605368|imex:IM-9152-857 author score:0.031056199 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65797(transcript)|ensemblbacteria:TP_0831(gene)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|refseq:WP_010882275.1|interpro:IPR035684|interpro:IPR036695 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0831; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aln69UFLKLBAAUJHdtg7+v6YzXE243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:84FF73719B20518A|rigid:BDLPZp7KIXVjNHQOqJRM1YlaohU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83793 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584868|ensemblbacteria:AAC65788 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y818_trepa(display_long)|uniprotkb:TP_0818(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605356|imex:IM-9152-855 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65788(transcript)|ensemblbacteria:TP_0818(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0818; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:QnxKmMr04H37/A461aRYWlKKgdE243276 intact-crc:03C4A12C6F01BDE8|rigid:P1uXrrU3X1AEcY9FDgurF6fb6As false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83803 uniprotkb:O83958 intact:EBI-1587743|ensemblbacteria:AAC65797 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:syr_trepa(display_long)|uniprotkb:argS(gene name)|psi-mi:argS(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:TP_0831(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605374|imex:IM-9152-858 author score:0.001893812 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|ensemblbacteria:AAC65797(transcript)|ensemblbacteria:TP_0831(gene)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|refseq:WP_010882275.1|interpro:IPR035684|interpro:IPR036695 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0831; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aln69UFLKLBAAUJHdtg7+v6YzXE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8A8CA208ABBEB191|rigid:J6I0YdXvxdrjGlxmkWuyhH8E2FI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83767 uniprotkb:O83975 intact:EBI-1582289|ensemblbacteria:AAC65763 intact:EBI-1605384|ensemblbacteria:AAC65962 psi-mi:y788_trepa(display_long)|uniprotkb:TP_0788(locus name) psi-mi:pth_trepa(display_long)|uniprotkb:pth(gene name)|psi-mi:pth(display_short)|uniprotkb:TP_1011(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605380|imex:IM-9152-859 author score:0.098786251 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65763(transcript)|ensemblbacteria:TP_0788(gene)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010882233.1 interpro:IPR001328(Peptidyl-tRNA hydrolase)|interpro:IPR018171|refseq:WP_010882455.1|ensemblbacteria:AAC65962(transcript)|ensemblbacteria:TP_1011(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|interpro:IPR036416 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1011; PREY protein TP_0788|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:RSeH1MUvLV0LT+8K8hNw+Wv3f4E243276 rogid:dsrrvsI7DmQ7qbDCYcjjhXd/XOg243276 intact-crc:7CD42C8C450790C1|rigid:2Vd3/80TczUpoyblUZECW+tdjHg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83975 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605384|ensemblbacteria:AAC65962 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:pth_trepa(display_long)|uniprotkb:pth(gene name)|psi-mi:pth(display_short)|uniprotkb:TP_1011(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605390|imex:IM-9152-860 author score:0.083230564 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001328(Peptidyl-tRNA hydrolase)|interpro:IPR018171|refseq:WP_010882455.1|ensemblbacteria:AAC65962(transcript)|ensemblbacteria:TP_1011(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|interpro:IPR036416 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1011; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:dsrrvsI7DmQ7qbDCYcjjhXd/XOg243276 intact-crc:697BDEB87C671E5B|rigid:tb/WulEUIbxpkJR+4XlDoUNH6K0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83975 uniprotkb:O83282 intact:EBI-1605384|ensemblbacteria:AAC65962 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:pth_trepa(display_long)|uniprotkb:pth(gene name)|psi-mi:pth(display_short)|uniprotkb:TP_1011(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605396|imex:IM-9152-861 author score:0.035073518 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001328(Peptidyl-tRNA hydrolase)|interpro:IPR018171|refseq:WP_010882455.1|ensemblbacteria:AAC65962(transcript)|ensemblbacteria:TP_1011(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|interpro:IPR036416 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1011; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dsrrvsI7DmQ7qbDCYcjjhXd/XOg243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:50F4B3FBF6D3E9E0|rigid:U+W4eN3n/lQHL57zn1K+5FwW7oU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83975 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605384|ensemblbacteria:AAC65962 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:pth_trepa(display_long)|uniprotkb:pth(gene name)|psi-mi:pth(display_short)|uniprotkb:TP_1011(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605402|imex:IM-9152-862 author score:0.001779001 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR001328(Peptidyl-tRNA hydrolase)|interpro:IPR018171|refseq:WP_010882455.1|ensemblbacteria:AAC65962(transcript)|ensemblbacteria:TP_1011(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|interpro:IPR036416 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1011; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:dsrrvsI7DmQ7qbDCYcjjhXd/XOg243276 intact-crc:14C2C62EB4582839|rigid:yLCPIpp+qBojN8OiI/KdrvWoksA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83080 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605412|ensemblbacteria:AAC65033 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:ldhd_trepa(display_long)|uniprotkb:ldhD(gene name)|psi-mi:ldhD(display_short)|uniprotkb:D-specific 2-hydroxyacid dehydrogenase(gene name synonym)|uniprotkb:TP_0037(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605408|imex:IM-9152-863 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|refseq:WP_010881486.1|ensemblbacteria:AAC65033(transcript)|ensemblbacteria:TP_0037(gene)|go:"GO:0008720"(D-lactate dehydrogenase activity)|go:"GO:0051287"(NAD binding)|interpro:IPR036291|rcsb pdb:7JP2 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0037; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:IVjmho34DATxVWqjc0OsFUVmVX0243276 intact-crc:932A2140F3FB29F8|rigid:yX+vpKuqBDQzZNeUnGB2+wcB/Z0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83091 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605418|ensemblbacteria:AAC65048|ensemblbacteria:AGN75272 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83091_trepa(display_long)|uniprotkb:prmC(gene name)|psi-mi:prmC(display_short)|uniprotkb:N5-glutamine methyltransferase PrmC(gene name synonym)|uniprotkb:"Protein-(glutamine-N5) MTase PrmC"(gene name synonym)|uniprotkb:Protein-glutamine N-methyltransferase PrmC(gene name synonym)|uniprotkb:TP_0052(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605421|imex:IM-9152-864 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR004556(Modification methylase HemK)|interpro:IPR019874|interpro:IPR040758|ensemblbacteria:AAC65048(transcript)|ensemblbacteria:AGN75272(transcript)|ensemblbacteria:TP_0052(gene)|ensemblbacteria:TPANIC_0052(gene)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0036009"(protein-glutamine N-methyltransferase activity)|go:"GO:0102559"("protein-(glutamine-N5) methyltransferase activity")|interpro:IPR029063 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0052; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:lA1hCfuhfqLYvCITke1ZwUC4aLA243276 intact-crc:7875DEE50C5DD5A2|rigid:Pn4qD6JaK3smfEVvrcQysXrDJmg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83147 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1583331|ensemblbacteria:AAC65100|ensemblbacteria:AGN75328 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:o83147_trepa(display_long)|uniprotkb:TP_0109(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605427|imex:IM-9152-865 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR004441(RNA methyltransferase TrmH, group 3)|interpro:IPR001537(tRNA/rRNA methyltransferase, SpoU)|ensemblbacteria:AAC65100(transcript)|ensemblbacteria:AGN75328(transcript)|ensemblbacteria:TP_0109(gene)|ensemblbacteria:TPANIC_0109(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|refseq:WP_010881558.1|interpro:IPR029026|interpro:IPR029028 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0109; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:4jhzBh20lX2enqR2C4ChM06aahI243276 intact-crc:78DBDE1E11F9815D|rigid:Ru7TflcaL0pK3LbVtPtgEulvn/k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83149 uniprotkb:O83745 intact:EBI-1586119|ensemblbacteria:AAC65101 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:rp54_trepa(display_long)|uniprotkb:rpoN(gene name)|psi-mi:rpoN(display_short)|uniprotkb:TP_0111(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605433|imex:IM-9152-866 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000394(RNA polymerase sigma factor 54)|interpro:IPR007046(RNA polymerase sigma factor 54, core-binding)|interpro:IPR007634(RNA polymerase sigma factor 54, DNA-binding)|ensemblbacteria:AAC65101(transcript)|ensemblbacteria:TP_0111(gene)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0111; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Swze8dOUOAa3pYgYd2J4MX+Rf2w243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:AA9B23A06D77C821|rigid:qaLh+WZ5UO3qJ9IeqQ+Hb1o1fNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83152 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605443|ensemblbacteria:AAC65104 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:hflc_trepa(display_long)|uniprotkb:hflC(gene name)|psi-mi:hflC(display_short)|uniprotkb:TP_0114(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605439|imex:IM-9152-867 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR001107(Band 7 protein)|interpro:IPR010200(HflC)|refseq:WP_010881563.1|ensemblbacteria:AAC65104(transcript)|ensemblbacteria:TP_0114(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052547"(regulation of peptidase activity)|interpro:IPR036013 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0114; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:olqAJNsF82F7WK+ubbb+vjWlg+k243276 intact-crc:C8EBB4A91E3FFCF7|rigid:Pw10dgCu6FVGS7pge/c3pdu37wQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83166 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605453|ensemblbacteria:AAC65121 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y129_trepa(display_long)|uniprotkb:TP_0129(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605449|imex:IM-9152-868 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 ensemblbacteria:AAC65121(transcript)|ensemblbacteria:TP_0129(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0129; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:NPVdYVAVmzVELkLrnPHi1/rJaAE243276 intact-crc:256F2298269C5520|rigid:zKosYAZIYXWekHvYniQS7jd4WL4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83223 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1198732|intact:EBI-1585859|ensemblbacteria:AAC65178 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rs19_trepa(display_long)|uniprotkb:rpsS(gene name)|psi-mi:rpsS(display_short)|uniprotkb:TP_0193(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605468|imex:IM-9152-870 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005732(Ribosomal protein S19, bacterial-type)|interpro:IPR020934|interpro:IPR023575|refseq:WP_010881640.1|ensemblbacteria:AAC65178(transcript)|ensemblbacteria:TP_0193(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0193; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:EBhFBJ6rA8hNYYWEGpwdquYzXqQ243276 intact-crc:C390B0885BDC94C6|rigid:3I998dwx8t/8SwGhQyJS717RbzQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83214 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605458|ensemblbacteria:AAC65169 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:ssrp_trepa(display_long)|uniprotkb:smpB(gene name)|psi-mi:smpB(display_short)|uniprotkb:Small protein B(gene name synonym)|uniprotkb:TP_0184(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605462|imex:IM-9152-869 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR023620|interpro:IPR000037(SmpB protein)|interpro:IPR020081|refseq:WP_010881631.1|ensemblbacteria:AAC65169(transcript)|ensemblbacteria:TP_0184(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0070929"(trans-translation) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0184; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:OLedLEHXd3prXxzrxIRR9fFGgnk243276 intact-crc:1E546574AB5B1DD9|rigid:z4YFfQO0QN7zMRqc13FwXyLBKP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83820 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605487|ensemblbacteria:AAC65814 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:rl20_trepa(display_long)|uniprotkb:rplT(gene name)|psi-mi:rplT(display_short)|uniprotkb:TP_0848(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605483|imex:IM-9152-872 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR005813(Ribosomal protein L20)|refseq:WP_010882292.1|ensemblbacteria:AAC65814(transcript)|ensemblbacteria:TP_0848(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR035566 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0848; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:f+0HqVPE4q5e3BP+LbiM+JHyPqU243276 intact-crc:8C928D7735108EB2|rigid:/u8IzpLftNrngcAYc4Hm46QTOfY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83633 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1605474|ensemblbacteria:AAC65604 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:y625_trepa(display_long)|uniprotkb:TP_0625(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605477|imex:IM-9152-871 author score:0.098742346 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 refseq:WP_010882071.1|ensemblbacteria:AAC65604(transcript)|ensemblbacteria:TP_0625(gene)|interpro:IPR011990(Tetratricopeptide-like helical) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0625; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:iMsG4IXt5Yrvlen0eZKc3y2vl5U243276 intact-crc:E96B98829C7D7B49|rigid:30apRT+vrNXjLm4TDAdiN4tBj1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83145 uniprotkb:O83745 intact:EBI-1605493|ensemblbacteria:AAC26555|ensemblbacteria:AGN75326 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:o83145_trepa(display_long)|uniprotkb:TP_0107(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605496|imex:IM-9152-873 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017190("Bifunctional CTP:phosphocholine cytidylyltransferase/choline kinase")|interpro:IPR011009(Protein kinase-like)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR025877|ensemblbacteria:TPANIC_0107(gene)|ensemblbacteria:AAC26555(transcript)|ensemblbacteria:AGN75326(transcript)|ensemblbacteria:TP_0107(gene)|interpro:IPR029044 interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0107; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:kA69Ee3HPq9Dte8fih/jLDkjcOU243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:D39550B15BDD39E1|rigid:b/MojnhYRUyyAEYDTM1Lvgeaayw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83145 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605493|ensemblbacteria:AAC26555|ensemblbacteria:AGN75326 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83145_trepa(display_long)|uniprotkb:TP_0107(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605502|imex:IM-9152-874 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR017190("Bifunctional CTP:phosphocholine cytidylyltransferase/choline kinase")|interpro:IPR011009(Protein kinase-like)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR025877|ensemblbacteria:TPANIC_0107(gene)|ensemblbacteria:AAC26555(transcript)|ensemblbacteria:AGN75326(transcript)|ensemblbacteria:TP_0107(gene)|interpro:IPR029044 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0107; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:kA69Ee3HPq9Dte8fih/jLDkjcOU243276 intact-crc:0826FE058CBB0919|rigid:VOk0nmEfMyHgGML1fiON/NynCrs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83451 uniprotkb:O83745 intact:EBI-1605512|ensemblbacteria:AAC65435 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 psi-mi:y437_trepa(display_long)|uniprotkb:TP_0437(locus name) psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605508|imex:IM-9152-875 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881885.1|ensemblbacteria:AAC65435(transcript)|ensemblbacteria:TP_0437(gene) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0437; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:EiV5kg/B6IQfz444hbYu823TYdQ243276 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 intact-crc:20F62A778359E489|rigid:uZUT5oKf8ZH0169wT6bfOQE0Zw4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83451 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605512|ensemblbacteria:AAC65435 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y437_trepa(display_long)|uniprotkb:TP_0437(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605517|imex:IM-9152-876 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010881885.1|ensemblbacteria:AAC65435(transcript)|ensemblbacteria:TP_0437(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0437; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:EiV5kg/B6IQfz444hbYu823TYdQ243276 intact-crc:FB4584C3543FD471|rigid:+ZRRCAeY6pJ6SdPMvTAyetjizog false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83745 uniprotkb:O83938 intact:EBI-1581810|ensemblbacteria:AAC65727|ensemblbacteria:AGN75937 intact:EBI-1587703|ensemblbacteria:AAC65930 psi-mi:o83745_trepa(display_long)|uniprotkb:TP_0764(locus name) psi-mi:syfa_trepa(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:TP_0973(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605523|imex:IM-9152-877 author score:0.093305037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65727(transcript)|ensemblbacteria:AGN75937(transcript)|ensemblbacteria:TP_0764(gene)|ensemblbacteria:TPANIC_0764(gene)|refseq:WP_010882209.1|interpro:IPR037522 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR022917|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|ensemblbacteria:AAC65930(transcript)|ensemblbacteria:TP_0973(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|refseq:WP_010882417.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0973; PREY protein TP_0764|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:D86Svi9tr46cKEJjhMOQad81Ers243276 rogid:NjlMzGYSGr173q4R8gEEajJDdTI243276 intact-crc:27D2BB0030E39C62|rigid:oOgkzCbP4LBgrleoCa8jdCNF+c4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83237 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605539|ensemblbacteria:AAC65197 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:rl15_trepa(display_long)|uniprotkb:rplO(gene name)|psi-mi:rplO(display_short)|uniprotkb:TP_0207(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605535|imex:IM-9152-879 author score:0.042021599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR005749(Ribosomal protein L15, bacterial-type)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR030878|refseq:WP_010881655.1|ensemblbacteria:AAC65197(transcript)|ensemblbacteria:TP_0207(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|interpro:IPR036227 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0207; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:7bvtcCOV3egxtM/mcBlMH8n/n1A243276 intact-crc:017CA568DA4696CF|rigid:iSkOSvp86Fzifdv3DbwxswVHUnw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83938 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1587703|ensemblbacteria:AAC65930 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:syfa_trepa(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:TP_0973(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605529|imex:IM-9152-878 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR022917|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|ensemblbacteria:AAC65930(transcript)|ensemblbacteria:TP_0973(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|refseq:WP_010882417.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0973; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:NjlMzGYSGr173q4R8gEEajJDdTI243276 intact-crc:C0AB90A7EB0CDFD8|rigid:VMMny1m7X72q33IkxuodULMJK3o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83264 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1198965|intact:EBI-1585097|ensemblbacteria:AAC65224 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:nusg_trepa(display_long)|uniprotkb:nusG(gene name)|psi-mi:nusG(display_short)|uniprotkb:TP_0236(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605545|imex:IM-9152-880 author score:0.042021599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR005824(KOW)|interpro:IPR001062(Transcription antitermination protein, NusG)|interpro:IPR015869(Transcription antitermination protein, NusG, bacteria, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR008991(Translation protein SH3-like)|refseq:WP_010881684.1|interpro:IPR043425|ensemblbacteria:AAC65224(transcript)|ensemblbacteria:TP_0236(gene)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR036735 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0236; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:xXU5PiV/OOduIUughdLPLggOh8A243276 intact-crc:563B13C14F2EC36B|rigid:i7SqNOWzuGPQmoqBw2MS7z3W4qw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P74929 uniprotkb:O83282 intact:EBI-1605565|uniprotkb:Q7DFP0 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:p74929_trepl(display_long)|uniprotkb:FA889_03725(orf name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:160(trepl)|taxid:160(Treponema pallidum) taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605561|imex:IM-9152-882 author score:0.042021599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022781|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044781"(bacterial-type flagellum organization)|refseq:WP_010882164.1 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0719; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:6jC0mLB9TaNXCLxJxe/9TDWer0A160 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:F077D45F03E461C8|rigid:LY5Qm4wbCMYg5we7vrTKim/Qstw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O07894 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605551|uniprotkb:Q7DFP4 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o07894_trepl(display_long)|uniprotkb:msp(gene name)|psi-mi:msp(display_short) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:160(trepl)|taxid:160(Treponema pallidum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605555|imex:IM-9152-881 author score:0.042021599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0621; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:j7Ft5tG+9qQBJF4EX57YndqD9Hw160 intact-crc:9FAEC89C243CCEF4|rigid:Azhgp/3ydH6T8v4sg+vNjCH01BI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O33844 uniprotkb:O83282 intact:EBI-1605570|ensemblbacteria:AAC65779 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:dma_trepa(display_long)|uniprotkb:dam(gene name)|psi-mi:dam(display_short)|uniprotkb:M.TpaI(gene name synonym)|uniprotkb:Deoxyadenosyl-methyltransferase(gene name synonym)|uniprotkb:DNA adenine methyltransferase(gene name synonym)|uniprotkb:TP_0810(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605574|imex:IM-9152-883 author score:0.042021599 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR023095|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR012263(Adenine modification methylase, M.EcoRV)|interpro:IPR012327(D12 class N6 adenine-specific DNA methyltransferase)|refseq:WP_010882255.1|ensemblbacteria:AAC65779(transcript)|ensemblbacteria:TP_0810(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009007"("site-specific DNA-methyltransferase (adenine-specific) activity")|interpro:IPR029063 ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0810; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:vFYD45PZQuYehChXL7C2D820gnc243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:8897C3D7F0CE59A4|rigid:uga3R6pCQ8fdh1qzYlKaNWRXfmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83153 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605580|ensemblbacteria:AAC65105 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:pdxk_trepa(display_long)|uniprotkb:Pyridoxal kinase(gene name synonym)|uniprotkb:pdxK(gene name)|psi-mi:pdxK(display_short)|uniprotkb:TP_0115(locus name)|uniprotkb:Vitamin B6 kinase(gene name synonym)|uniprotkb:Pyridoxamine kinase(gene name synonym)|uniprotkb:PN/PL/PM kinase(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605584|imex:IM-9152-884 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|refseq:WP_010881564.1|ensemblbacteria:AAC65105(transcript)|ensemblbacteria:TP_0115(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008478"(pyridoxal kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029056 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0115; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:gm9Dpyqw6mKqIbGqS9rX7BCJzWo243276 intact-crc:161965A090AB1001|rigid:3juowunpIRWSVhRZHgrAVNYpDKU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83153 uniprotkb:O83958 intact:EBI-1605580|ensemblbacteria:AAC65105 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:pdxk_trepa(display_long)|uniprotkb:Pyridoxal kinase(gene name synonym)|uniprotkb:pdxK(gene name)|psi-mi:pdxK(display_short)|uniprotkb:TP_0115(locus name)|uniprotkb:Vitamin B6 kinase(gene name synonym)|uniprotkb:Pyridoxamine kinase(gene name synonym)|uniprotkb:PN/PL/PM kinase(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605590|imex:IM-9152-885 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013749(Phosphomethylpyrimidine kinase type-1)|interpro:IPR004399(Phosphomethylpyrimidine kinase type-2)|refseq:WP_010881564.1|ensemblbacteria:AAC65105(transcript)|ensemblbacteria:TP_0115(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0008478"(pyridoxal kinase activity)|go:"GO:0008972"(phosphomethylpyrimidine kinase activity)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR029056 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0115; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:gm9Dpyqw6mKqIbGqS9rX7BCJzWo243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8C45B77F4E5E567E|rigid:a8LWq7lt/6u/kx1h8HMb/MUffO4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83282 uniprotkb:O83765 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 intact:EBI-1605596|ensemblbacteria:AAC65755|ensemblbacteria:AGN75958 psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:o83765_trepa(display_long)|uniprotkb:TP_0786(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605599|imex:IM-9152-886 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR032823|interpro:IPR027417|interpro:IPR030921|refseq:WP_010882231.1|ensemblbacteria:AAC65755(transcript)|ensemblbacteria:AGN75958(transcript)|ensemblbacteria:TP_0786(gene)|ensemblbacteria:TPANIC_0786(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0786; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 rogid:+g2bvgLTo5t94HP2oSCnp46tEI0243276 intact-crc:5F6B819090A3A82C|rigid:Y5kCWaSRIAv6ClP2DHZFOsNufWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83765 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605596|ensemblbacteria:AAC65755|ensemblbacteria:AGN75958 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83765_trepa(display_long)|uniprotkb:TP_0786(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605605|imex:IM-9152-887 author score:0.004342466 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR032823|interpro:IPR027417|interpro:IPR030921|refseq:WP_010882231.1|ensemblbacteria:AAC65755(transcript)|ensemblbacteria:AGN75958(transcript)|ensemblbacteria:TP_0786(gene)|ensemblbacteria:TPANIC_0786(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex") psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0786; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:+g2bvgLTo5t94HP2oSCnp46tEI0243276 intact-crc:B5C8E3C9E382B05E|rigid:R/Aa+rFZ7G7Ln2EdqN9ES4DEIYY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83778 uniprotkb:O83282 intact:EBI-1605611|ensemblbacteria:AAC65769|ensemblbacteria:AGN75972 intact:EBI-1582172|ensemblbacteria:AAC65247|ensemblbacteria:AGN75470 psi-mi:o83778_trepa(display_long)|uniprotkb:TP_0800(locus name) psi-mi:o83282_trepa(display_long)|uniprotkb:TP_0258(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605614|imex:IM-9152-888 author score:0.03957052 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:WP_010882245.1|ensemblbacteria:AAC65769(transcript)|ensemblbacteria:AGN75972(transcript)|ensemblbacteria:TP_0800(gene)|ensemblbacteria:TPANIC_0800(gene)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0071555"(cell wall organization) ensemblbacteria:AAC65247(transcript)|ensemblbacteria:AGN75470(transcript)|ensemblbacteria:TP_0258(gene)|ensemblbacteria:TPANIC_0258(gene)|refseq:WP_010881707.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0800; PREY protein TP_0258|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:HyqMfvY05IJKc8v2tUkPUKxeMNw243276 rogid:fLN1RgSWDUIDEfDGmdQ/TJ5zNus243276 intact-crc:AC335E00A1246921|rigid:uTpenPZXFzsf675bNXuMMpzAKwU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83778 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1605611|ensemblbacteria:AAC65769|ensemblbacteria:AGN75972 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83778_trepa(display_long)|uniprotkb:TP_0800(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605620|imex:IM-9152-889 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR018044|interpro:IPR001967(Peptidase S11, D-alanyl-D-alanine carboxypeptidase A)|refseq:WP_010882245.1|ensemblbacteria:AAC65769(transcript)|ensemblbacteria:AGN75972(transcript)|ensemblbacteria:TP_0800(gene)|ensemblbacteria:TPANIC_0800(gene)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0071555"(cell wall organization) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0800; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:HyqMfvY05IJKc8v2tUkPUKxeMNw243276 intact-crc:BADE968938058B01|rigid:oFvg0vzHOmnVX2t1mZqZR0cmdzI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83335 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1605626|ensemblbacteria:AAC65300|ensemblbacteria:AGN75516 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83335_trepa(display_long)|uniprotkb:TP_0313(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605629|imex:IM-9152-890 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|refseq:WP_010881762.1|ensemblbacteria:AAC65300(transcript)|ensemblbacteria:TP_0313(gene)|ensemblbacteria:TPANIC_0313(gene)|ensemblbacteria:AGN75516(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0313; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:Bd69amYGKddYnbtmdZy/+AwmnV8243276 intact-crc:C1CF563EEE0F008C|rigid:Hq1ynSSoVwEUciZoo7sq6fT0+/s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83336 uniprotkb:O83954 intact:EBI-1198975|intact:EBI-1585224|ensemblbacteria:AAC65305 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y314_trepa(display_long)|uniprotkb:TP_0314(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605635|imex:IM-9152-891 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|ensemblbacteria:AAC65305(transcript)|ensemblbacteria:TP_0314(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0314; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:rjZuIwOLYsidiK8cJHZrG52uw9o243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:F81C75F32B242249|rigid:l1SXTpupq81Gn14Tsmy6yFPf3G0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83428 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1198445|intact:EBI-1582090|ensemblbacteria:AAC65401|ensemblbacteria:AGN75608 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83428_trepa(display_long)|uniprotkb:TP_0413(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605641|imex:IM-9152-892 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|refseq:WP_010881861.1|ensemblbacteria:AAC65401(transcript)|ensemblbacteria:AGN75608(transcript)|ensemblbacteria:TP_0413(gene)|ensemblbacteria:TPANIC_0413(gene)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016868"(intramolecular transferase activity, phosphotransferases)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0413; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:xdf7iMFGW04XcnA65OQGOvw/VAE243276 intact-crc:37AE1D84BAC54C9F|rigid:JtCpmbxhLBxeYPAjonuhSfTOcNQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83439 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1586134|ensemblbacteria:AAC65411 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:vate_trepa(display_long)|uniprotkb:atpE(gene name)|psi-mi:atpE(display_short)|uniprotkb:V-ATPase subunit E(gene name synonym)|uniprotkb:TP_0424(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605647|imex:IM-9152-893 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65411(transcript)|ensemblbacteria:TP_0424(gene)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006811"(ion transport) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0424; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:thNeo9prIZeKnVV0CklqTbWHGZQ243276 intact-crc:D8E692214764B5C7|rigid:I9HvmdO2mMQwMdVvO6JGZ7qrawI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83626 uniprotkb:O83954 intact:EBI-1605653|ensemblbacteria:AAC65593 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:y617_trepa(display_long)|uniprotkb:TP_0617(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605656|imex:IM-9152-894 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024471|refseq:WP_010882063.1|ensemblbacteria:AAC65593(transcript)|ensemblbacteria:TP_0617(gene) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0617; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:w+PivtcdqH6tqgrjgpaNjAunSdI243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:59865A2708CF7ADA|rigid:FccZd1cvnbsYZSz5+rdJEWr6x/g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83640 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583301|ensemblbacteria:AAC65607 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:syw_trepa(display_long)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:trpS(gene name)|psi-mi:trpS(display_short)|uniprotkb:trsA(gene name synonym)|uniprotkb:TP_0632(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605662|imex:IM-9152-895 author score:0.035056828 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) ensemblbacteria:AAC65607(transcript)|ensemblbacteria:TP_0632(gene)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|interpro:IPR024109|refseq:WP_010882078.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0632; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:i+LUDNbkZaxwLqc2AQr1bAEBBZQ243276 intact-crc:F8A8FBFB1214651E|rigid:LND7oJsyGXTNPJSO6XNsj8OTqtE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83836 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1583992|ensemblbacteria:AAC65827|ensemblbacteria:AGN76033 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83836_trepa(display_long)|uniprotkb:TP_0864(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605668|imex:IM-9152-896 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|ensemblbacteria:AAC65827(transcript)|ensemblbacteria:AGN76033(transcript)|ensemblbacteria:TP_0864(gene)|ensemblbacteria:TPANIC_0864(gene)|refseq:WP_010882308.1|interpro:IPR036779 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0864; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:U5uJqBTWMZMzPVYqM8Opx1Vsplg243276 intact-crc:1192AA7DF682606B|rigid:lgZA+FKJEqdJaGWh6s7Fg9KfN1I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83836 uniprotkb:O83958 intact:EBI-1583992|ensemblbacteria:AAC65827|ensemblbacteria:AGN76033 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83836_trepa(display_long)|uniprotkb:TP_0864(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605674|imex:IM-9152-897 author score:0.003431943 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011055(Duplicated hybrid motif)|interpro:IPR016047(Peptidase M23)|interpro:IPR018392|ensemblbacteria:AAC65827(transcript)|ensemblbacteria:AGN76033(transcript)|ensemblbacteria:TP_0864(gene)|ensemblbacteria:TPANIC_0864(gene)|refseq:WP_010882308.1|interpro:IPR036779 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0864; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:U5uJqBTWMZMzPVYqM8Opx1Vsplg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9AF82F9D58043CEF|rigid:dFgpUkzzwkUPoWI+885g12NGLWE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83954 uniprotkb:O83919 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 intact:EBI-1605680|ensemblbacteria:AAC65908|ensemblbacteria:AGN76118 psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:o83919_trepa(display_long)|uniprotkb:TP_0953(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605683|imex:IM-9152-898 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) interpro:IPR002816(Pheromone shutdown-related, TraB)|interpro:IPR005230(Pheromone shutdown, TraB)|ensemblbacteria:AAC65908(transcript)|ensemblbacteria:AGN76118(transcript)|ensemblbacteria:TP_0953(gene)|ensemblbacteria:TPANIC_0953(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0953; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 rogid:zQP2z/zaNN1q0/QiZ1GJZgR3kxY243276 intact-crc:14BA2E4B5322427F|rigid:LopuVvea6PIWEYBFW7N9t3Px5rk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83919 uniprotkb:O83958 intact:EBI-1605680|ensemblbacteria:AAC65908|ensemblbacteria:AGN76118 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83919_trepa(display_long)|uniprotkb:TP_0953(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605689|imex:IM-9152-899 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002816(Pheromone shutdown-related, TraB)|interpro:IPR005230(Pheromone shutdown, TraB)|ensemblbacteria:AAC65908(transcript)|ensemblbacteria:AGN76118(transcript)|ensemblbacteria:TP_0953(gene)|ensemblbacteria:TPANIC_0953(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0953; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:zQP2z/zaNN1q0/QiZ1GJZgR3kxY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9D1F6C21DC690BA5|rigid:sgyElqdz8cHIiQFGUe3EJ2v526E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83954 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1581935|ensemblbacteria:AAC65945|ensemblbacteria:AGN76153 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:o83954_trepa(display_long)|uniprotkb:TP_0989(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605695|imex:IM-9152-900 author score:0.032998003 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR032640|ensemblbacteria:AAC65945(transcript)|ensemblbacteria:AGN76153(transcript)|ensemblbacteria:TP_0989(gene)|ensemblbacteria:TPANIC_0989(gene)|refseq:WP_010882433.1|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR013783(Immunoglobulin-like fold) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1004; PREY protein TP_0989|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:ys2QcO8dx8ZPK1XkgsQnQURbv9s243276 intact-crc:A7FE28910988911B|rigid:h7bg3eZdaH+JLYDCcBYINNvK0eA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83969 uniprotkb:O83958 intact:EBI-1581850|ensemblbacteria:AAC65952 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:recr_trepa(display_long)|uniprotkb:recR(gene name)|psi-mi:recR(display_short)|uniprotkb:TP_1004(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605701|imex:IM-9152-901 author score:0.002016017 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000093(RecR protein)|interpro:IPR023627|interpro:IPR015967(Zinc finger C4-type, RecR)|interpro:IPR006171(TOPRIM)|ensemblbacteria:AAC65952(transcript)|ensemblbacteria:TP_1004(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0046872"(metal ion binding)|refseq:WP_010882448.1|interpro:IPR034137 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1004; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aNEdk3sF0pxmiDbseaLd+35gL+s243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:B558DDBBCA006BBE|rigid:ntkDqzcPRzVY0FXOJ+Tgh9eKOng false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83741 uniprotkb:O83958 intact:EBI-1198893|intact:EBI-1588495|ensemblbacteria:AAC65726|ensemblbacteria:AGN75933 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83741_trepa(display_long)|uniprotkb:TP_0760(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605707|imex:IM-9152-902 author score:0.01070321 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR005543(PASTA)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|refseq:WP_010882205.1|ensemblbacteria:AAC65726(transcript)|ensemblbacteria:AGN75933(transcript)|ensemblbacteria:TP_0760(gene)|ensemblbacteria:TPANIC_0760(gene)|go:"GO:0008658"(penicillin binding)|go:"GO:0016020"(membrane)|interpro:IPR036138 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0760; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:1VwIquwM2EcCFCPSBYI3bC9UWSY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:5C2AE3B00C132622|rigid:Q8n4Z2HlytiesfZ7lhIAahGMIDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83632 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605717|ensemblbacteria:AAC65597|ensemblbacteria:AGN75805 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83632_trepa(display_long)|uniprotkb:TP_0624(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605713|imex:IM-9152-903 author score:0.004391237 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006665(Outer membrane protein, OmpA/MotB, C-terminal)|refseq:WP_010882070.1|rcsb pdb:5JIR|ensemblbacteria:AAC65597(transcript)|ensemblbacteria:AGN75805(transcript)|ensemblbacteria:TP_0624(gene)|ensemblbacteria:TPANIC_0624(gene)|go:"GO:0016020"(membrane)|interpro:IPR036737 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0624; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:h1pQIN5r2DkbZSn36iAhyT6E5TU243276 intact-crc:5BDAFA51890FCED3|rigid:+ZlnKnzJ36AqDSSJW/q9veEA8/Q false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83877 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1581925|ensemblbacteria:AAC65859 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rimm_trepa(display_long)|uniprotkb:rimM(gene name)|psi-mi:rimM(display_short)|uniprotkb:TP_0907(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605722|imex:IM-9152-904 author score:0.003911351 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011961(16S rRNA processing protein RimM)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR002676(RimM protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblbacteria:AAC65859(transcript)|ensemblbacteria:TP_0907(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043022"(ribosome binding)|interpro:IPR036976 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0907; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:aADqweSwsXSoYTRX/u+uxUcRMt4243276 intact-crc:D03B8A59D5653588|rigid:bTJTpVM6SOy0R3d7kP8ObhwcOs4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83455 uniprotkb:O83958 intact:EBI-1605740|ensemblbacteria:AAC65428 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:nadk_trepa(display_long)|uniprotkb:nadK(gene name)|psi-mi:nadK(display_short)|uniprotkb:ATP-dependent NAD kinase(gene name synonym)|uniprotkb:TP_0441(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605744|imex:IM-9152-907 author score:0.003265941 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR002504(ATP-NAD/AcoX kinase)|refseq:WP_010881889.1|ensemblbacteria:AAC65428(transcript)|ensemblbacteria:TP_0441(gene)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0046872"(metal ion binding) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0441; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Ww8hiYwE9VXfcrBNdVz6gwFTMEA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:2D8B96086F521E20|rigid:MQQe8RKA06gHyBJH5K5U9ZFTWyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83676 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1596649|ensemblbacteria:AAC26568 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:ddl_trepa(display_long)|uniprotkb:ddl(gene name)|psi-mi:ddl(display_short)|uniprotkb:ddlA(gene name synonym)|uniprotkb:D-alanylalanine synthetase(gene name synonym)|uniprotkb:D-Ala-D-Ala ligase(gene name synonym)|uniprotkb:TP_0670(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605728|imex:IM-9152-905 author score:0.003632296 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011127(D-alanine--D-alanine ligase, N-terminal)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR000291(D-alanine--D-alanine ligase/VANA/B/C, conserved site)|interpro:IPR005905(D-alanine--D-alanine ligase)|interpro:IPR011095(D-alanine--D-alanine ligase, C-terminal)|interpro:IPR016185(PreATP-grasp-like fold)|ensemblbacteria:AAC26568(transcript)|ensemblbacteria:TP_0670(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008716"(D-alanine-D-alanine ligase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071555"(cell wall organization)|refseq:WP_010882115.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0670; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:3zdRrMBrjY/9kju33T37PHuMZ3A243276 intact-crc:810F11E103A01211|rigid:+eM0l/xWtqbbMFY//YBAnkvh2Vs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83983 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1586373|ensemblbacteria:AAC65970 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:gata_trepa(display_long)|uniprotkb:gatA(gene name)|psi-mi:gatA(display_short)|uniprotkb:TP_1020(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605734|imex:IM-9152-906 author score:0.003272149 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000120(Amidase signature enzyme)|interpro:IPR020556|interpro:IPR023631|interpro:IPR004412("Glutamyl-tRNA(Gln) amidotransferase A subunit")|ensemblbacteria:AAC65970(transcript)|ensemblbacteria:TP_1020(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|refseq:WP_010882464.1|interpro:IPR036928 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_1020; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:M+KheF38jzx6H71RxIAdEJXnNfQ243276 intact-crc:7771991DD633A6F6|rigid:4cJ8FovoxDzILjpUN8RMKOI/E24 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83491 uniprotkb:O83958 intact:EBI-1605750|ensemblbacteria:AAC65465 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:g6pd_trepa(display_long)|uniprotkb:zwf(gene name)|psi-mi:zwf(display_short)|uniprotkb:TP_0478(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605754|imex:IM-9152-908 author score:0.003027037 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022675|interpro:IPR022674|refseq:WP_010881927.1|ensemblbacteria:AAC65465(transcript)|ensemblbacteria:TP_0478(gene)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0050661"(NADP binding)|interpro:IPR036291 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0478; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:raPYZm8K348/mZw9r+Pdrd3Od94243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1F167C0A890295BC|rigid:WZJA1Dxrcf6KFlpYzuqyvENo+4I false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83307 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605764|ensemblbacteria:AAC65267 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:coad_trepa(display_long)|uniprotkb:coaD(gene name)|psi-mi:coaD(display_short)|uniprotkb:kdtB(gene name synonym)|uniprotkb:Pantetheine-phosphate adenylyltransferase(gene name synonym)|uniprotkb:Dephospho-CoA pyrophosphorylase(gene name synonym)|uniprotkb:TP_0283(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605760|imex:IM-9152-909 author score:0.003009838 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR001980(Coenzyme A biosynthesis protein)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:WP_010881732.1|ensemblbacteria:AAC65267(transcript)|ensemblbacteria:TP_0283(gene)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015937"(coenzyme A biosynthetic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0283; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:T82auSgRhWJppC1kZbbuD9kPnSY243276 intact-crc:1D109597192FC5E4|rigid:/c0RpzDQjUkDbHyjEEUYSGH04VM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83906 uniprotkb:O83958 intact:EBI-1605774|ensemblbacteria:AAC65893|ensemblbacteria:AGN76101 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83906_trepa(display_long)|uniprotkb:TP_0936(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605770|imex:IM-9152-910 author score:0.002992737 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR005170(Transporter-associated region)|refseq:WP_010882379.1|ensemblbacteria:AAC65893(transcript)|ensemblbacteria:AGN76101(transcript)|ensemblbacteria:TP_0936(gene)|ensemblbacteria:TPANIC_0936(gene)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036318|interpro:IPR044751 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0936; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:9HdmdNQvRdj2dOPoTY9j/fsi2/w243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:D2271ADF6FAF8CC3|rigid:Tkxnmv8npehW8R08EEvSacpQdL8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83047 uniprotkb:O83958 intact:EBI-1582316|ensemblbacteria:AAC64999 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605779|imex:IM-9152-911 author score:0.002859367 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0001; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:9B9AF61ADDBC034F|rigid:gu/mfEvtumAEicrRl3uFNABYRys false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83105 uniprotkb:O83958 intact:EBI-1198263|intact:EBI-1581649|ensemblbacteria:AAC65065 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y066_trepa(display_long)|uniprotkb:TP_0066(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605785|imex:IM-9152-912 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010881515.1|ensemblbacteria:AAC65065(transcript)|ensemblbacteria:TP_0066(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0066; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:OgIwnpHkXS1MrqK0JPsRajZYVaM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:84D043CE32B695F9|rigid:8dzUMVq2alU8pN5jNd7g/pmTlFo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83252 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605801|ensemblbacteria:AAC65212|ensemblbacteria:AGN75437 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83252_trepa(display_long)|uniprotkb:TP_0223(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605797|imex:IM-9152-914 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|ensemblbacteria:AAC65212(transcript)|ensemblbacteria:AGN75437(transcript)|ensemblbacteria:TP_0223(gene)|ensemblbacteria:TPANIC_0223(gene)|go:"GO:0008483"(transaminase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0223; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:vkjo8BR1W4VhaLJMZaOl872UMUI243276 intact-crc:B66C5ED6787F818F|rigid:f0hq1KSBZq86pgzDtjyJDwgsbsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83163 uniprotkb:O83958 intact:EBI-1584611|ensemblbacteria:AAC65118 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y126_trepa(display_long)|uniprotkb:TP_0126(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605791|imex:IM-9152-913 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65118(transcript)|ensemblbacteria:TP_0126(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR011250(Outer membrane protein, beta-barrel) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0126; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ciO/q3x+ouX8MJuNI0cs1fC4ZcY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:272AF3A22D6E8D39|rigid:w87kiXZOoY1wEI/KIy65iPgb9nI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83471 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605819|ensemblbacteria:AAC65446|ensemblbacteria:AGN75652 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83471_trepa(display_long)|uniprotkb:TP_0458(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605815|imex:IM-9152-916 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005234(Prokaryotic chromosome segregation and condensation protein ScpB)|refseq:WP_010881907.1|ensemblbacteria:AAC65446(transcript)|ensemblbacteria:AGN75652(transcript)|ensemblbacteria:TP_0458(gene)|ensemblbacteria:TPANIC_0458(gene)|go:"GO:0051304"(chromosome separation)|go:"GO:0051301"(cell division)|interpro:IPR036388|interpro:IPR036390 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0458; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Vg0RSe3x+Sjr9KIuEDGhu0k2u74243276 intact-crc:A1290EFF7FB811DB|rigid:NeG/X10JKLCCZrOYmncKq3vdz5E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83290 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605806|ensemblbacteria:AAC65261 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y266_trepa(display_long)|uniprotkb:TP_0266(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605809|imex:IM-9152-915 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65261(transcript)|ensemblbacteria:TP_0266(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0266; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:kbtfW2E7qsDWLh+56X3PgHE8ZE8243276 intact-crc:93D050D03641F67D|rigid:HzxNwpvnzGKKv36kEljzu/p6/DU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83475 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1584020|uniprotkb:O83476|ensemblbacteria:AAC65455|ensemblbacteria:AAC65456 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y462_trepa(display_long)|uniprotkb:TP_0462/TP_0463(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605824|imex:IM-9152-917 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65455(transcript)|ensemblbacteria:AAC65456(transcript)|ensemblbacteria:TP_0462(gene)|ensemblbacteria:TP_0463(gene)|go:"GO:0005886"(plasma membrane) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0463; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:rm9EmFCXF1hSrjcHRWt6dsY4e9M243276 intact-crc:FE505BED8CDF9428|rigid:imtwuGca7Do0lmrANlqVveIGyGQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83486 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1583663|ensemblbacteria:AAC65467 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y473_trepa(display_long)|uniprotkb:TP_0473(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605830|imex:IM-9152-918 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 ensemblbacteria:AAC65467(transcript)|ensemblbacteria:TP_0473(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:WP_010881922.1 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0473; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Xo9b8/eVrjrXZxeEcrbobakqDg8243276 intact-crc:7808078CB4382B43|rigid:zfeZ0DVI1WIsCUJwnfIySAstQQ8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83562 uniprotkb:O83958 intact:EBI-1605836|ensemblbacteria:AAC65536|ensemblbacteria:AGN75738 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83562_trepa(display_long)|uniprotkb:TP_0551(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605839|imex:IM-9152-919 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|refseq:WP_010881998.1|ensemblbacteria:AAC65536(transcript)|ensemblbacteria:AGN75738(transcript)|ensemblbacteria:TP_0551(gene)|ensemblbacteria:TPANIC_0551(gene)|interpro:IPR036938 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0551; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GPbcu7/JmqUOalpZJYvC7ZVls70243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:EEA216DD116797EB|rigid:8H+OVoEFtRReHMUvEfVRLKxEDPw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83573 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605845|ensemblbacteria:AAC65539|ensemblbacteria:AGN75749 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83573_trepa(display_long)|uniprotkb:TP_0562(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605848|imex:IM-9152-920 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006190(Antifreeze-like/N-acetylneuraminic acid synthase C-terminal)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR013132(N-acetylneuraminic acid synthase, N-terminal)|interpro:IPR013974(SAF domain)|refseq:WP_010882009.1|ensemblbacteria:AAC65539(transcript)|ensemblbacteria:AGN75749(transcript)|ensemblbacteria:TP_0562(gene)|ensemblbacteria:TPANIC_0562(gene)|go:"GO:0003824"(catalytic activity)|go:"GO:0016051"(carbohydrate biosynthetic process) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0562; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Y/jJEhalcxSwkDumJS76yGC+ZFA243276 intact-crc:072A9978E8C26EB7|rigid:IIu1omOdJ4WEd5gp1q8pWhu+6pc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83620 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605854|ensemblbacteria:AAC65587|ensemblbacteria:AGN75792 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83620_trepa(display_long)|uniprotkb:TP_0611(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605857|imex:IM-9152-921 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010230(SUF system FeS cluster assembly, SufC ATPase)|interpro:IPR027417|refseq:WP_010882057.1|ensemblbacteria:AAC65587(transcript)|ensemblbacteria:AGN75792(transcript)|ensemblbacteria:TP_0611(gene)|ensemblbacteria:TPANIC_0611(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0611; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:VFLg5gi/yy9zyi0HU66wCR6ZWuc243276 intact-crc:601E60C25C61FE3E|rigid:Z2StT3xUaEZ/7cnNbebeLonDBfU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83669 uniprotkb:O83958 intact:EBI-1605863|ensemblbacteria:AAC65636 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83669_trepa(display_long)|uniprotkb:TP_0663(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605866|imex:IM-9152-922 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006714(Flagellar filament outer layer protein FlaA)|ensemblbacteria:AAC65636(transcript)|ensemblbacteria:TP_0663(gene)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0055040"(periplasmic flagellum)|go:"GO:0071973"(bacterial-type flagellum-dependent cell motility)|refseq:WP_010882108.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0663; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Nyp+7hJvS8HFMCBxfB0+8D+CCOY243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:42F1602602587AF4|rigid:HGULwidE5ds1VKZ5zQt3QTvJ1vM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83688 uniprotkb:O83958 intact:EBI-1605885|ensemblbacteria:AAC65664 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y690_trepa(display_long)|uniprotkb:TP_0690(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605881|imex:IM-9152-924 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882135.1|ensemblbacteria:AAC65664(transcript)|ensemblbacteria:TP_0690(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0690; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:Tbnh0eN8s03Nbh66yMqMjqRfQ0s243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1A18602F013B1301|rigid:lhBDo6BBFZp8AP+sgUg4Y0QIWmQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83672 uniprotkb:O83958 intact:EBI-1605876|ensemblbacteria:AAC65642 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y666_trepa(display_long)|uniprotkb:TP_0666(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605872|imex:IM-9152-923 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882111.1|ensemblbacteria:AAC65642(transcript)|ensemblbacteria:TP_0666(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0666; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:TUIUvMjW2PT0CdnvVjmWqpS7k4Q243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:2081F72F71104E22|rigid:f5u7ccX7YMqKnTxBFmA188foto8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83694 uniprotkb:O83958 intact:EBI-1605890|ensemblbacteria:AAC65663|ensemblbacteria:AGN75874 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83694_trepa(display_long)|uniprotkb:TP_0696(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605893|imex:IM-9152-925 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882141.1|ensemblbacteria:AAC65663(transcript)|ensemblbacteria:AGN75874(transcript)|ensemblbacteria:TP_0696(gene)|ensemblbacteria:TPANIC_0696(gene)|interpro:IPR036380 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0696; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:lSsrwk3jLMmM4jOZNiusbJQWBeE243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:158051F94B3383EE|rigid:DUiw2o/rdt6khk9w2K+PE7DscGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83715 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1585506|ensemblbacteria:AAC65708 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:y733_trepa(display_long)|uniprotkb:TP_0733(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605899|imex:IM-9152-926 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011250(Outer membrane protein, beta-barrel)|ensemblbacteria:AAC65708(transcript)|ensemblbacteria:TP_0733(gene)|refseq:WP_010882178.1|interpro:IPR027385 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0733; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:JoBcpKMiJuxGO9+5lVaZ/sprnVQ243276 intact-crc:124922B934930842|rigid:g4RXAheBvZMxMiyz+4vk3TyWI1A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83722 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605905|ensemblbacteria:AAC65709|ensemblbacteria:AGN75914 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83722_trepa(display_long)|uniprotkb:TP_0740(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605908|imex:IM-9152-927 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR005249(Conserved hypothetical protein CHP00488)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|ensemblbacteria:AAC65709(transcript)|ensemblbacteria:AGN75914(transcript)|ensemblbacteria:TP_0740(gene)|ensemblbacteria:TPANIC_0740(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0740; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:/M334i4jv3BnU9z+QcorqJ6MRkA243276 intact-crc:CCE85745C0168759|rigid:IhMPBZ+s38w1z3Q+abXqJqD1/Sk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83725 uniprotkb:O83958 intact:EBI-1198423|intact:EBI-1582016|ensemblbacteria:AAC65717 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:rl27_trepa(display_long)|uniprotkb:rpmA(gene name)|psi-mi:rpmA(display_short)|uniprotkb:TP_0743(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605914|imex:IM-9152-928 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001684(Ribosomal protein L27)|interpro:IPR018261|refseq:WP_010882188.1|ensemblbacteria:AAC65717(transcript)|ensemblbacteria:TP_0743(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0743; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:GQ/6oHmhMagaYddfIwAckdCCmUA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:A100F19AF9562360|rigid:Hrt5cs6kD/8lOVgISYSKMqVonLE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:Q56336 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605920|ensemblbacteria:AAC65715 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:cfpa_trepa(display_long)|uniprotkb:cfpA(gene name)|psi-mi:cfpA(display_short)|uniprotkb:tpn83(gene name synonym)|uniprotkb:TP_0748(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605924|imex:IM-9152-929 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 refseq:WP_010882193.1|ensemblbacteria:AAC65715(transcript)|ensemblbacteria:TP_0748(gene)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0748; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Iu6YIdhDrDwVmuH6gnCG8g47luw243276 intact-crc:BB40210669B0EBBC|rigid:qEw3Y6G/qZ5WsO+znr7d+yZz4sY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83740 uniprotkb:O83958 intact:EBI-1605930|ensemblbacteria:AAC65731 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y759_trepa(display_long)|uniprotkb:TP_0759(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605933|imex:IM-9152-947 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65731(transcript)|ensemblbacteria:TP_0759(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0759; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:IBEBuhL/tDijLwQ86/m8mp7PfMU243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:36AFA38B2EAD1D69|rigid:Lnpqz05HxyMDYIf8qj5NJW7dOGM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83742 uniprotkb:O83958 intact:EBI-1587278|ensemblbacteria:AAC65732 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y761_trepa(display_long)|uniprotkb:TP_0761(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605939|imex:IM-9152-931 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65732(transcript)|ensemblbacteria:TP_0761(gene)|refseq:WP_010882206.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0761; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:2iVnAjV5YAmDmbht1QVYHFya8sg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:1080B1025A91DD1D|rigid:rzYPZeKgLuQRC6XoZZbSXmv6pZ4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07643 uniprotkb:O83958 intact:EBI-1586327|ensemblbacteria:AAC65736 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:tmpa_trepa(display_long)|uniprotkb:tmpA(gene name)|psi-mi:tmpA(display_short)|uniprotkb:Membrane protein A(gene name synonym)|uniprotkb:TP_0768(locus name)|uniprotkb:Antigen TmpA(gene name synonym) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605945|imex:IM-9152-932 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC65736(transcript)|ensemblbacteria:TP_0768(gene)|go:"GO:0005886"(plasma membrane)|refseq:WP_010882213.1 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0768; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:JOFboMvIWFcoRVVL+x6PwCJ8v68243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:7380803088D7A2B5|rigid:7aGz6ZjEZVgzksrASICvuDixMOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83818 uniprotkb:O83958 intact:EBI-1605955|ensemblbacteria:AAC65819 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y846_trepa(display_long)|uniprotkb:TP_0846(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605951|imex:IM-9152-933 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007838(Cell division protein ZapA-like)|refseq:WP_010882290.1|ensemblbacteria:AAC65819(transcript)|ensemblbacteria:TP_0846(gene)|interpro:IPR036192 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0846; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:A8AAUyFcHvN8Sa2401LBuzfbrQA243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:101CEF952BC0A062|rigid:xPPdOQA9Hcy1sCnC+Q4hBuXc8Uc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83831 uniprotkb:O83958 intact:EBI-1605960|uniprotkb:O83832|ensemblbacteria:AAC65831|ensemblbacteria:AAC65832 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y859_trepa(display_long)|uniprotkb:TP_0859/TP_0860(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605963|imex:IM-9152-934 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005362(Protein of unknown function UPF0164)|refseq:WP_014342835.1|ensemblbacteria:AAC65831(transcript)|ensemblbacteria:AAC65832(transcript)|ensemblbacteria:TP_0859(gene)|ensemblbacteria:TP_0860(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0860; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:aKHgHhVXxWvT3BFq9vLoKpeUkNQ243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:EDFF1936EA7C79E9|rigid:v2jWqTw5loyV69utWoEz/O4I+L0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83861 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582542|ensemblbacteria:AAC26581 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:if2_trepa(display_long)|uniprotkb:infB(gene name)|psi-mi:infB(display_short)|uniprotkb:TP_0891(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605969|imex:IM-9152-935 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR006847(Translation initiation factor IF-2, N-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR000178(Initiation factor 2)|interpro:IPR023115|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR044145|ensemblbacteria:AAC26581(transcript)|ensemblbacteria:TP_0891(gene)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR027417|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR036925 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0891; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:WX9JOC/Dy+FEJolWvf7M4MEWMwI243276 intact-crc:8C30CC52BD34028F|rigid:Y1EnndSpKAtPDElceuMQhnLAmr0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83867 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1582373|uniprotkb:Q9L8S8|ensemblbacteria:AAC65852 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83867_trepa(display_long)|uniprotkb:TP_0897(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605975|imex:IM-9152-936 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR003872(Major outer sheath protein, C-terminal)|interpro:IPR003857(Major outer sheath protein, N-terminal)|ensemblbacteria:AAC65852(transcript)|ensemblbacteria:TP_0897(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0897; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:y95b2chNjqHprky4Hz7Mtv4aFCg243276 intact-crc:F2168BC93F6A470D|rigid:kNL7Q889QJWPn9AsN3F2lfM3vUs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83872 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1605981|ensemblbacteria:AGN76070|ensemblbacteria:AAC65855 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83872_trepa(display_long)|uniprotkb:TP_0902(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605984|imex:IM-9152-937 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR012354(Esterase/lipase)|refseq:WP_010882345.1|ensemblbacteria:AAC65855(transcript)|ensemblbacteria:AGN76070(transcript)|ensemblbacteria:TP_0902(gene)|ensemblbacteria:TPANIC_0902(gene)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029058 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0902; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:+GtCRywrK31/BTJuAH2b6wR+T/c243276 intact-crc:422AD0CE38AC33AE|rigid:RcI0/Kpmfc1Bb+G9jEl9bkiu1og false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83876 uniprotkb:O83958 intact:EBI-1590563|ensemblbacteria:AAC65858 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y906_trepa(display_long)|uniprotkb:TP_0906(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605990|imex:IM-9152-938 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR020627|interpro:IPR015946(K homology-like, alpha/beta)|ensemblbacteria:AAC65858(transcript)|ensemblbacteria:TP_0906(gene)|go:"GO:0003723"(RNA binding) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0906; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:ztZdpo9fvxIqrxId/E5ul1Vpceg243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:161155DCC4C7B552|rigid:gvM+o1nMjzZYlDlzPPyC+AUnD3c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83914 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1606005|ensemblbacteria:AAC65897|ensemblbacteria:AGN76108 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83914_trepa(display_long)|uniprotkb:TP_0944(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606008|imex:IM-9152-940 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR011990(Tetratricopeptide-like helical)|refseq:WP_010882387.1|ensemblbacteria:AAC65897(transcript)|ensemblbacteria:AGN76108(transcript)|ensemblbacteria:TP_0944(gene)|ensemblbacteria:TPANIC_0944(gene) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0944; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:BTQOPTMSMsEg2W5b3wY+DoViO8o243276 intact-crc:673CE5ACC0369472|rigid:YfT51sHIJqh6CoRgQRlyeIJAJyM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83905 uniprotkb:O83958 intact:EBI-1605996|ensemblbacteria:AAC65892|ensemblbacteria:AGN76100 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:o83905_trepa(display_long)|uniprotkb:TP_0935(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1605999|imex:IM-9152-939 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013094(Alpha/beta hydrolase fold-3)|refseq:WP_010882378.1|ensemblbacteria:AAC65892(transcript)|ensemblbacteria:AGN76100(transcript)|ensemblbacteria:TP_0935(gene)|ensemblbacteria:TPANIC_0935(gene)|go:"GO:0016787"(hydrolase activity)|interpro:IPR029058 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0935; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:7X1I18/UeErDSC6e6hoVZjFwoBc243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:8B12AA093B95692C|rigid:d35VPFzC5FRaqUjcE1wo0mXIcWU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O83923 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1606026|ensemblbacteria:AAC65913|ensemblbacteria:AGN76122 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:o83923_trepa(display_long)|uniprotkb:TP_0957(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606029|imex:IM-9152-943 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR018389|rcsb pdb:3U65|rcsb pdb:4DI3|rcsb pdb:4DI4|interpro:IPR038404|refseq:WP_010882401.1|ensemblbacteria:AAC65913(transcript)|ensemblbacteria:AGN76122(transcript)|ensemblbacteria:TP_0957(gene)|ensemblbacteria:TPANIC_0957(gene)|go:"GO:0055085"(transmembrane transport) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0957; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:0L0iYSi1Pus6lGLFXYzKC0cglhE243276 intact-crc:BC38305034B51D69|rigid:oXR6X7GR848ZLAACibRfcMv7d1M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83958 uniprotkb:O66107 intact:EBI-1581658|ensemblbacteria:AAC65949 intact:EBI-1198932|intact:EBI-1582205|ensemblbacteria:AAC65902 psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:rpe_trepa(display_long)|uniprotkb:rpe(gene name)|psi-mi:rpe(display_short)|uniprotkb:TP_0945(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606014|imex:IM-9152-941 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR000056(Ribulose-phosphate 3-epimerase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR026019|refseq:WP_010882388.1|ensemblbacteria:TP_0945(gene)|go:"GO:0004750"(D-ribulose-phosphate 3-epimerase activity)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0019323"(pentose catabolic process)|go:"GO:0046872"(metal ion binding)|ensemblbacteria:AAC65902(transcript) psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0945; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 rogid:Zt4OFLZhm+dYolU7BOrVpwKzYyI243276 intact-crc:AC90D55616954677|rigid:HucsyGYratWatFeSmDuktigMh04 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83922 uniprotkb:O83958 intact:EBI-1587649|ensemblbacteria:AAC65922 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y956_trepa(display_long)|uniprotkb:TP_0956(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606020|imex:IM-9152-942 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031823|refseq:WP_010882400.1|ensemblbacteria:AAC65922(transcript)|ensemblbacteria:TP_0956(gene)|rcsb pdb:3U64|rcsb pdb:4DI3|rcsb pdb:4DI4|interpro:IPR038537 interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0956; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:NALMbkkfnIBkTf88VZuBrTQwseM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:A936D1148BAFFCD6|rigid:IZw9VI+38ahMFh5Sda1oP+UUXx4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83939 uniprotkb:O83958 intact:EBI-1198653|intact:EBI-1582237|ensemblbacteria:AAC65939 intact:EBI-1581658|ensemblbacteria:AAC65949 psi-mi:y974_trepa(display_long)|uniprotkb:TP_0974(locus name) psi-mi:rlpa_trepa(display_long)|uniprotkb:rlpA(gene name)|psi-mi:rlpA(display_short)|uniprotkb:TP_0993(locus name) psi-mi:"MI:0397"(two hybrid array) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606035|imex:IM-9152-944 author score:0.002146091 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010882418.1|ensemblbacteria:AAC65939(transcript)|ensemblbacteria:TP_0974(gene) interpro:IPR009009(Barwin-related endoglucanase)|interpro:IPR012997(Rare lipoprotein A, bacterial)|ensemblbacteria:AAC65949(transcript)|ensemblbacteria:TP_0993(gene)|go:"GO:0000270"(peptidoglycan metabolic process)|go:"GO:0008932"(lytic endotransglycosylase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0071555"(cell wall organization)|interpro:IPR034718|refseq:WP_010882437.1|interpro:IPR036908 psi-mi:"MI:0469"(intact) - - author-identifiers:BAIT protein TP_0974; PREY protein TP_0993|figure legend:Supplementary table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/18 2014/10/16 rogid:dIYhG7fW7dCmnIWQPBFgtbS6zSM243276 rogid:iFcnJftETtOh5aKgRDyCugHOlzo243276 intact-crc:CC35261DFFE2CA07|rigid:XGu3H4F89vMVCo+rnx9HY0KxbGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O83050 uniprotkb:O08399 intact:EBI-1584836|ensemblbacteria:AAC65005 intact:EBI-1585657|ensemblbacteria:AAC65954 psi-mi:y004_trepa(display_long)|uniprotkb:TP_0004(locus name) psi-mi:gyrb_trepa(display_long)|uniprotkb:gyrB(gene name)|psi-mi:gyrB(display_short)|uniprotkb:TP_1006(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1767849|imex:IM-9152-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007922(Protein of unknown function DUF721)|ensemblbacteria:AAC65005(transcript)|ensemblbacteria:TP_0004(gene)|refseq:WP_010881454.1 interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011557(DNA gyrase, subunit B)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR018522|interpro:IPR006171(TOPRIM)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|ensemblbacteria:AAC65954(transcript)|go:"GO:0006265"(DNA topological change)|ensemblbacteria:TP_1006(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|refseq:WP_010882450.1|interpro:IPR034160|interpro:IPR036890 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:IxAoquYRvbXKT9V9t6ETfHG8dHo243276 rogid:OkQQ4SjHW9+OzASF/QiIYqo75Lg243276 intact-crc:4CF3F849892B5D99|rigid:ssC7IHBmTPrt7x6cvmeugxqSalY false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83634 uniprotkb:O83213 intact:EBI-1198617|intact:EBI-1584700|ensemblbacteria:AAC65598|ensemblbacteria:AGN75807 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:o83634_trepa(display_long)|uniprotkb:sbcD(gene name)|psi-mi:sbcD(display_short)|uniprotkb:TP_0626(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768057|imex:IM-9152-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004843(Metallophosphoesterase)|interpro:IPR004593(Exonuclease SbcD)|interpro:IPR029052|refseq:WP_010882072.1|ensemblbacteria:AAC65598(transcript)|ensemblbacteria:AGN75807(transcript)|ensemblbacteria:TP_0626(gene)|ensemblbacteria:TPANIC_0626(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006310"(DNA recombination)|go:"GO:0008408"(3'-5' exonuclease activity)|interpro:IPR041796 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:aD1a0Pl1LoF6pBzOaVZoimmq0zo243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:792AEB361A356B75|rigid:bJxjfRvJFIl/QaGaSHtm2oX5ofo false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83047 uniprotkb:O83213 intact:EBI-1582316|ensemblbacteria:AAC64999 intact:EBI-1589991|ensemblbacteria:AAC65196 psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:y183_trepa(display_long)|uniprotkb:TP_0183(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768083|imex:IM-9152-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 ensemblbacteria:AAC65196(transcript)|ensemblbacteria:TP_0183(gene)|refseq:WP_010881630.1 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 rogid:ZsiEJEMkd00Bn+NJwrVj/Ew88is243276 intact-crc:ED95397FF8620B34|rigid:MYK+8PdxnZe4sSEfCV87BFFGWkY false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83047 uniprotkb:O83097 intact:EBI-1582316|ensemblbacteria:AAC64999 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:dnaa_trepa(display_long)|uniprotkb:dnaA(gene name)|psi-mi:dnaA(display_short)|uniprotkb:TP_0001(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768113|imex:IM-9152-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024633|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001957(Bacterial chromosomal replication initiator protein, DnaA)|interpro:IPR020591|interpro:IPR018312|interpro:IPR013159(Chromosomal replication initiator, DnaA C-terminal)|interpro:IPR013317(Chromosomal replication initiator, DnaA)|interpro:IPR010921(Trp repressor/replication initiator)|ensemblbacteria:AAC64999(transcript)|ensemblbacteria:TP_0001(gene)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006275"(regulation of DNA replication)|refseq:WP_010881451.1|interpro:IPR038454|interpro:IPR027417 interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:2JwKuSoM0Jci2t8xGC4g3Etimko243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:0D95397E9F181D7E|rigid:tLjbjk5ofFR1L5XW0Wpy3FkF8MY false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83089 uniprotkb:O83097 intact:EBI-1198251|intact:EBI-1581685|ensemblbacteria:AAC65046|ensemblbacteria:AGN75270 intact:EBI-1582320|ensemblbacteria:AAC65054 psi-mi:o83089_trepa(display_long)|uniprotkb:TP_0050(locus name) psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768149|imex:IM-9152-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|refseq:WP_010881499.1|ensemblbacteria:AAC65046(transcript)|ensemblbacteria:AGN75270(transcript)|ensemblbacteria:TP_0050(gene)|ensemblbacteria:TPANIC_0050(gene)|go:"GO:0009116"(nucleoside metabolic process) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:6kpnozteYMX2TDiA1FVX5q9ShGA243276 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 intact-crc:3212EF14DF1A41C4|rigid:dq2QAe1ZspIQ2LaJ0woCRiqx9ns false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83097 uniprotkb:O83130 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1198269|intact:EBI-1581640|ensemblbacteria:AAC65087|ensemblbacteria:AGN75311 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83130_trepa(display_long)|uniprotkb:TP_0092(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768237|imex:IM-9152-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR013249(RNA polymerase sigma factor 70, region 4 type 2)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR039425|refseq:WP_010881541.1|ensemblbacteria:AAC65087(transcript)|ensemblbacteria:AGN75311(transcript)|ensemblbacteria:TP_0092(gene)|ensemblbacteria:TPANIC_0092(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016987"(sigma factor activity)|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:ySAhqn50dr44ZqwSkVXd1PCOyTI243276 intact-crc:0410165B2364A8D2|rigid:VeCEe/WAxKh21feFNrtIpJ7ZhX8 false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83097 uniprotkb:O83970 intact:EBI-1582320|ensemblbacteria:AAC65054 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:dnab_trepa(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:TP_0058(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768263|imex:IM-9152-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|ensemblbacteria:AAC65054(transcript)|ensemblbacteria:TP_0058(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR027417|interpro:IPR036185 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:Ee25WCgKqMDsFUHyz8G8lGwCp84243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:C410165B2203D276|rigid:4RCspZHyl/mfkN07OLrdhQB5u6M false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83107 uniprotkb:O83970 intact:EBI-1585371|ensemblbacteria:AAC65061 intact:EBI-1582351|ensemblbacteria:AAC65953|ensemblbacteria:AGN76169 psi-mi:rlmn_trepa(display_long)|uniprotkb:rlmN(gene name)|psi-mi:rlmN(display_short)|uniprotkb:23S rRNA m2A2503 methyltransferase(gene name synonym)|uniprotkb:"23S rRNA (adenine(2503)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:Ribosomal RNA large subunit methyltransferase N(gene name synonym)|uniprotkb:"tRNA (adenine(37)-C(2))-methyltransferase"(gene name synonym)|uniprotkb:tRNA m2A37 methyltransferase(gene name synonym)|uniprotkb:TP_0068(locus name) psi-mi:o83970_trepa(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:TP_1005(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768271|imex:IM-9152-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR004383(Conserved hypothetical protein CHP00048)|interpro:IPR007197(Radical SAM)|ensemblbacteria:AAC65061(transcript)|ensemblbacteria:TP_0068(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002935"("tRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070040"("rRNA (adenine-C2-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|refseq:WP_010881517.1|interpro:IPR027492|interpro:IPR040072 interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR022754|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|ensemblbacteria:AAC65953(transcript)|ensemblbacteria:AGN76169(transcript)|ensemblbacteria:TP_1005(gene)|ensemblbacteria:TPANIC_1005(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|refseq:WP_010882449.1|interpro:IPR027417 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:N4P6uNVku5oSt8I5AAjzbkzHK3A243276 rogid:80joyY4PtRbNFvd8ALJlyyJf65w243276 intact-crc:32547BCA054729A4|rigid:AuOWDv4jHS58e/ZY2T5uZHitVDk false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O83538 uniprotkb:O83862 intact:EBI-1585740|ensemblbacteria:AAC65513|ensemblbacteria:AGN75714 intact:EBI-1585751|ensemblbacteria:AAC65849|ensemblbacteria:AGN76061 psi-mi:o83538_trepa(display_long)|uniprotkb:TP_0526(locus name) psi-mi:o83862_trepa(display_long)|uniprotkb:nusA(gene name)|psi-mi:nusA(display_short)|uniprotkb:TP_0892(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Titz et al. imex:IM-9152|doi:10.1371/journal.pone.0002292|pubmed:18509523 taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1768289|imex:IM-9152-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|ensemblbacteria:AAC65513(transcript)|ensemblbacteria:AGN75714(transcript)|ensemblbacteria:TP_0526(gene)|ensemblbacteria:TPANIC_0526(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|refseq:WP_010881974.1|interpro:IPR027417 interpro:IPR025249|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|interpro:IPR013735(Transcription factor NusA, N-terminal)|interpro:IPR010213(Transcription termination factor NusA)|ensemblbacteria:AAC65849(transcript)|ensemblbacteria:AGN76061(transcript)|ensemblbacteria:TP_0892(gene)|ensemblbacteria:TPANIC_0892(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0031564"(transcription antitermination)|interpro:IPR030842|refseq:WP_010882335.1|interpro:IPR036555 psi-mi:"MI:0469"(intact) - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2008/01/18 2014/10/16 rogid:Yty5i3EVwVg/KtKLE+dALkOXE1w243276 rogid:Es4UvnovxiVAigRDLtBkmPjV03I243276 intact-crc:2756C4979E04C3DB|rigid:97iGERZV3yTWidUjz1dpo3qJ4RU false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)