#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q69ZN7	uniprotkb:Q8BH64	intact:EBI-1994301|uniprotkb:Q8BU64|uniprotkb:Q8BU70|uniprotkb:Q8BUC1|uniprotkb:Q8C0D1|uniprotkb:Q7TMG0|uniprotkb:Q80V33|uniprotkb:Q8BVY6|uniprotkb:Q8R3B4|ensembl:ENSMUSP00000045036	intact:EBI-1994334|uniprotkb:Q8BL28|ensembl:ENSMUSP00000096397	psi-mi:myof_mouse(display_long)|uniprotkb:Myof(gene name)|psi-mi:Myof(display_short)|uniprotkb:Kiaa1207(gene name synonym)|uniprotkb:Fer1l3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	psi-mi:ehd2_mouse(display_long)|uniprotkb:Ehd2(gene name)|psi-mi:Ehd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Doherty et al. (2008)	pubmed:18502764|imex:IM-19176	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1994351|imex:IM-19176-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093104.1|refseq:NP_001289069.1|ensembl:ENSMUSG00000048612(gene)|ensembl:ENSMUST00000041475(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030947"(regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0061025"(membrane fusion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029999|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q69ZN7|go:"GO:0001778"(plasma membrane repair)	refseq:XP_011248884.1|refseq:NP_694708.2|dip:DIP-46806N|ensembl:ENSMUSG00000074364(gene)|ensembl:ENSMUST00000098799(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|rcsb pdb:2QPT|rcsb pdb:4CID|reactome:R-MMU-983231	-	-	-	figure legend:1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2008/09/19	2014/10/16	rogid:FQq1tTfF2Sam8Ae+7rdqAtdvLuk10090	rogid:Y6gH2n3nnVFeqaZE0T6T2gGqtyw10090	intact-crc:027F452969696A03|rigid:poyHnV/f5kBsovRfu65aKzNPYGY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NZM1	uniprotkb:Q8BH64	intact:EBI-1994363|uniprotkb:Q5VWW2|uniprotkb:Q5VWW3|uniprotkb:Q5VWW4|uniprotkb:Q5VWW5|uniprotkb:Q7Z642|uniprotkb:Q8IWH0|uniprotkb:Q9HBU3|uniprotkb:Q9NZM0|uniprotkb:Q9ULL3|uniprotkb:Q9Y4U4|uniprotkb:B3KQN5|ensembl:ENSP00000352208	intact:EBI-1994334|uniprotkb:Q8BL28|ensembl:ENSMUSP00000096397	psi-mi:myof_human(display_long)|uniprotkb:MYOF(gene name)|psi-mi:MYOF(display_short)|uniprotkb:KIAA1207(gene name synonym)|uniprotkb:FER1L3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	psi-mi:ehd2_mouse(display_long)|uniprotkb:Ehd2(gene name)|psi-mi:Ehd2(display_short)	psi-mi:"MI:0047"(far western blotting)	Doherty et al. (2008)	pubmed:18502764|imex:IM-19176	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1994435|imex:IM-19176-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038479.1|refseq:NP_579899.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029999|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q9NZM1|rcsb pdb:2DMH|rcsb pdb:2K2O|rcsb pdb:6EEL|ensembl:ENSG00000138119(gene)|ensembl:ENST00000359263(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006936"(muscle contraction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008015"(blood circulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0061025"(membrane fusion)	refseq:XP_011248884.1|refseq:NP_694708.2|dip:DIP-46806N|ensembl:ENSMUSG00000074364(gene)|ensembl:ENSMUST00000098799(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|rcsb pdb:2QPT|rcsb pdb:4CID|reactome:R-MMU-983231	-	-	-	figure legend:2C and D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/19	2014/10/16	rogid:YbWzqcootZO0/w6OLRqxZEEAu9U9606	rogid:Y6gH2n3nnVFeqaZE0T6T2gGqtyw10090	intact-crc:4D7121D8C5D8F6A4|rigid:UjwZv38fqRPDrBrpDKKYOTf1p8I	false	glutathione s tranferase tag:?-?|binding-associated region:200-306(IPR000008)|binding-associated region:238-240|mutation decreasing interaction:238-238	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q69ZN7	uniprotkb:Q8BH64	intact:EBI-1994301|uniprotkb:Q8BU64|uniprotkb:Q8BU70|uniprotkb:Q8BUC1|uniprotkb:Q8C0D1|uniprotkb:Q7TMG0|uniprotkb:Q80V33|uniprotkb:Q8BVY6|uniprotkb:Q8R3B4|ensembl:ENSMUSP00000045036	intact:EBI-1994334|uniprotkb:Q8BL28|ensembl:ENSMUSP00000096397	psi-mi:myof_mouse(display_long)|uniprotkb:Myof(gene name)|psi-mi:Myof(display_short)|uniprotkb:Kiaa1207(gene name synonym)|uniprotkb:Fer1l3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym)	psi-mi:ehd2_mouse(display_long)|uniprotkb:Ehd2(gene name)|psi-mi:Ehd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Doherty et al. (2008)	pubmed:18502764|imex:IM-19176	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2010908|imex:IM-19176-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001093104.1|refseq:NP_001289069.1|ensembl:ENSMUSG00000048612(gene)|ensembl:ENSMUST00000041475(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030947"(regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0061025"(membrane fusion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029999|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q69ZN7|go:"GO:0001778"(plasma membrane repair)	refseq:XP_011248884.1|refseq:NP_694708.2|dip:DIP-46806N|ensembl:ENSMUSG00000074364(gene)|ensembl:ENSMUST00000098799(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|rcsb pdb:2QPT|rcsb pdb:4CID|reactome:R-MMU-983231	-	-	-	figure legend:1B|comment:14 prey proteins have been captured by MS/MS including eight keratin-related intermediate filament proteins and two RNA-binding proteins which have not been further specified. with the exception of EHD2, the author regarded these proteins as probable contaminants so they have not been included in the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast)	-	2008/09/19	2014/10/16	rogid:FQq1tTfF2Sam8Ae+7rdqAtdvLuk10090	rogid:Y6gH2n3nnVFeqaZE0T6T2gGqtyw10090	intact-crc:1A0EBF8F166F3CEF|rigid:poyHnV/f5kBsovRfu65aKzNPYGY	false	-	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)