#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q79V61	uniprotkb:Q79V60	intact:EBI-7570699|intact:MINT-5224299|uniprotkb:Q8RR34|ensemblbacteria:BAC08034	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaib_theeb(display_long)|uniprotkb:kaiB(gene name)|psi-mi:kaiB(display_short)|uniprotkb:tlr0482(locus name)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0276"(blue native page)	Pattanayek et al. (2008)	pubmed:18497745|imex:IM-9564|mint:MINT-6798379|doi:10.1038/emboj.2008.104	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7934738|mint:MINT-6798386|imex:IM-9564-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011056333.1|mint:Q79V61|refseq:NP_681272.1|ensemblbacteria:BAC08034(gene)|ensemblbacteria:BAC08034(transcript)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042326"(negative regulation of phosphorylation)|interpro:IPR013474(Circadian clock protein KaiB)|interpro:IPR036249|interpro:IPR039022|rcsb pdb:1VGL|rcsb pdb:2QKE|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:5JYT|rcsb pdb:5JYV|interpro:IPR011649(KaiB)|dip:DIP-29356N|mint:MINT-6798389(identity)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798388(identity)	-	crc64:BC6B71EFBE6254E3|comment:mint|function:Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of kaiC. It has no effect on kaiC by itself, but instead needs the presence of both kaiA and kaiC, suggesting that it acts by antagonizing the interaction between kaiA and kaiC	crc64:34E4CDF9DE9C1824	figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2014/10/16	rogid:c4FTkp1XxfvbyRhMGe2Mh+zZJaU197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:F0FDD71EBCC477DD|rigid:VlmjpCA25QymY4/4Txtig6PJT0g	false	-	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q79V61	uniprotkb:Q79V60	intact:EBI-7570699|intact:MINT-5224299|uniprotkb:Q8RR34|ensemblbacteria:BAC08034	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaib_theeb(display_long)|uniprotkb:kaiB(gene name)|psi-mi:kaiB(display_short)|uniprotkb:tlr0482(locus name)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0276"(blue native page)	Pattanayek et al. (2008)	pubmed:18497745|imex:IM-9564|mint:MINT-6798379|doi:10.1038/emboj.2008.104	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7934749|mint:MINT-6798395|imex:IM-9564-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011056333.1|mint:Q79V61|refseq:NP_681272.1|ensemblbacteria:BAC08034(gene)|ensemblbacteria:BAC08034(transcript)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042326"(negative regulation of phosphorylation)|interpro:IPR013474(Circadian clock protein KaiB)|interpro:IPR036249|interpro:IPR039022|rcsb pdb:1VGL|rcsb pdb:2QKE|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:5JYT|rcsb pdb:5JYV|interpro:IPR011649(KaiB)|dip:DIP-29356N|mint:MINT-6798397(identity)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798399(identity)	-	crc64:BC6B71EFBE6254E3|comment:mint|function:Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of kaiC. It has no effect on kaiC by itself, but instead needs the presence of both kaiA and kaiC, suggesting that it acts by antagonizing the interaction between kaiA and kaiC	crc64:34E4CDF9DE9C1824	figure legend:F3b f3d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2014/10/16	rogid:c4FTkp1XxfvbyRhMGe2Mh+zZJaU197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:021835414A18152C|rigid:VlmjpCA25QymY4/4Txtig6PJT0g	false	glutathione s tranferase tag:?-?(MINT-6798413)	binding-associated region:?-?(MINT-6798416)|glutathione s tranferase tag:?-?(MINT-6798410)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q79V60	uniprotkb:Q79V62	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	intact:EBI-701584|uniprotkb:Q8RR35|ensemblbacteria:BAC08033	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaia_theeb(display_long)|uniprotkb:kaiA(gene name)|psi-mi:kaiA(display_short)|uniprotkb:tlr0481(locus name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Pattanayek et al. (2008)	pubmed:18497745|imex:IM-9564|mint:MINT-6798379|doi:10.1038/emboj.2008.104	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7934782|mint:MINT-6798457|imex:IM-9564-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798461(identity)	refseq:NP_681271.1|refseq:WP_011056332.1|dip:DIP-29355N|mint:Q79V62|ensemblbacteria:BAC08033(gene)|ensemblbacteria:BAC08033(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042802"(identical protein binding)|interpro:IPR011006(CheY-like)|interpro:IPR011648(KaiA)|interpro:IPR017944|interpro:IPR020844|interpro:IPR020856|rcsb pdb:1Q6A|rcsb pdb:1Q6B|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:1V2Z|rcsb pdb:5JWR|mint:MINT-6798459(identity)	-	crc64:34E4CDF9DE9C1824	crc64:D3B0DCBE8A580B4E	figure legend:F3F|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	rogid:CeRDujd+nzKBpU7pTDOvj5aG1aQ197221	intact-crc:83228BCA9C486CA0|rigid:z1+X3JbI7AV4LMiQo0zHCO5Aa9c	false	binding-associated region:?-?(MINT-6798466)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q79V61	uniprotkb:Q79V60	intact:EBI-7570699|intact:MINT-5224299|uniprotkb:Q8RR34|ensemblbacteria:BAC08034	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaib_theeb(display_long)|uniprotkb:kaiB(gene name)|psi-mi:kaiB(display_short)|uniprotkb:tlr0482(locus name)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0040"(electron microscopy)	Pattanayek et al. (2008)	pubmed:18497745|imex:IM-9564|mint:MINT-6798379|doi:10.1038/emboj.2008.104	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7934809|mint:MINT-6798425|imex:IM-9564-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011056333.1|mint:Q79V61|refseq:NP_681272.1|ensemblbacteria:BAC08034(gene)|ensemblbacteria:BAC08034(transcript)|go:"GO:0007623"(circadian rhythm)|go:"GO:0042326"(negative regulation of phosphorylation)|interpro:IPR013474(Circadian clock protein KaiB)|interpro:IPR036249|interpro:IPR039022|rcsb pdb:1VGL|rcsb pdb:2QKE|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:5JYT|rcsb pdb:5JYV|interpro:IPR011649(KaiB)|dip:DIP-29356N|mint:MINT-6798433(identity)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798427(identity)	-	crc64:BC6B71EFBE6254E3|comment:mint|function:Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of kaiC. It has no effect on kaiC by itself, but instead needs the presence of both kaiA and kaiC, suggesting that it acts by antagonizing the interaction between kaiA and kaiC	crc64:34E4CDF9DE9C1824	figure legend:SF4 SF5 F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2014/10/16	rogid:c4FTkp1XxfvbyRhMGe2Mh+zZJaU197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:5A07CCF13DC9A9F6|rigid:VlmjpCA25QymY4/4Txtig6PJT0g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q79V60	uniprotkb:Q79V60	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	intact:EBI-701595|uniprotkb:Q8RR33|ensemblbacteria:BAC08035	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:kaic_theeb(display_long)|uniprotkb:tlr0483(locus name)|uniprotkb:kaiC(gene name)|psi-mi:kaiC(display_short)	psi-mi:"MI:0040"(electron microscopy)	Pattanayek et al. (2008)	pubmed:18497745|imex:IM-9564|mint:MINT-6798379|doi:10.1038/emboj.2008.104	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	taxid:197221(theeb)|taxid:197221("Thermosynechococcus elongatus (strain BP-1)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7934820|mint:MINT-6798443|imex:IM-9564-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798447(identity)	refseq:NP_681273.1|refseq:WP_011056334.1|dip:DIP-29357N|mint:Q79V60|ensemblbacteria:BAC08035(gene)|ensemblbacteria:BAC08035(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016301"(kinase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR010624(Circadian clock protein KaiC)|interpro:IPR013503(Circadian clock, KaiC)|interpro:IPR014774(Circadian clock protein KaiC, central region)|interpro:IPR027417|interpro:IPR030665|rcsb pdb:1SUY|rcsb pdb:1SV1|rcsb pdb:4O0M|rcsb pdb:5JWO|rcsb pdb:5JWQ|rcsb pdb:5JWR|rcsb pdb:6X61|mint:MINT-6798447(identity)	-	crc64:34E4CDF9DE9C1824|comment:"Stoichiometry: 6.0"	crc64:34E4CDF9DE9C1824|comment:"Stoichiometry: 6.0"	figure legend:F3A F3C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/11/10	2014/10/16	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	rogid:a1ZoONc+Pzygqkgy0Sg69my2G9o197221	intact-crc:EBC8E805B4D70A6F|rigid:J34Cs6aVH71mufKg+r4ucWerICo	false	binding-associated region:1-250(MINT-6798452)	binding-associated region:1-250(MINT-6798452)	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)