#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49333	uniprotkb:Q9ZNV9	intact:EBI-1606682|ensemblplants:AT1G66340.1	intact:EBI-1100673|ensemblplants:AT3G21510.1	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:ahp1_arath(display_long)|uniprotkb:AHP1(gene name)|psi-mi:AHP1(display_short)|uniprotkb:ATHP3(gene name synonym)|uniprotkb:At3g21510(locus name)|uniprotkb:MIL23.8(orf name)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Scharein et al. (2008)	pubmed:18384742	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1787947	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	rcsb pdb:4EUK|ensemblplants:AT3G21510(gene)|ensemblplants:AT3G21510.1(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009553"(embryo sac development)|go:"GO:0009736"(cytokinin-activated signaling pathway)|go:"GO:0009825"(multidimensional cell growth)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0043424"(protein histidine kinase binding)|refseq:NP_188788.1|interpro:IPR008207("Signal transduction histidine kinase, phosphotransfer (Hpt) region")|interpro:IPR036641	-	-	-	figure legend:Figure 3 Figure 4|kinetics:"Kd (dissociation constant) 1.43x10exp6 -/+ 0.29 M"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/07/03	2014/10/16	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	rogid:QDjaEO3myNFVWwTQCwsfiseN5NY3702	intact-crc:C9F89B3E2EAD0585|rigid:+H6hpKdzDYln12DSdb3yi3WUzyo	false	his tag:?-?|necessary binding region:610-738	green fluorescent protein tag:c-c|his tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P49333	uniprotkb:P49333	intact:EBI-1606682|ensemblplants:AT1G66340.1	intact:EBI-1606682|ensemblplants:AT1G66340.1	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:etr1_arath(display_long)|uniprotkb:ETR1(gene name)|psi-mi:ETR1(display_short)|uniprotkb:T27F4.9(orf name)|uniprotkb:At1g66340(locus name)|uniprotkb:Protein ETHYLENE RESPONSE 1(gene name synonym)|uniprotkb:Protein ETR1(gene name synonym)	psi-mi:"MI:0841"(phosphotransferase assay)	Scharein et al. (2008)	pubmed:18384742	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1787967	-	-	psi-mi:"MI:0843"(phosphate acceptor)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	rcsb pdb:4PL9|refseq:NP_176808.3|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR011006(CheY-like)|interpro:IPR003018(GAF)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR014525(Signal transduction histidine kinase, hybrid-type, ethylene sensor)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|rcsb pdb:1DCF|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009739"(response to gibberellin)|go:"GO:0010087"(phloem or xylem histogenesis)|go:"GO:0010105"(negative regulation of ethylene-activated signaling pathway)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0010162"(seed dormancy process)|go:"GO:0010182"(sugar mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038199"(ethylene receptor activity)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051301"(cell division)|go:"GO:0051740"(ethylene binding)|go:"GO:0052544"(defense response by callose deposition in cell wall)|go:"GO:1900140"(regulation of seedling development)|interpro:IPR029016|ensemblplants:AT1G66340(gene)|ensemblplants:AT1G66340.1(transcript)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009408"(response to heat)|go:"GO:0009625"(response to insect)|go:"GO:0009651"(response to salt stress)|go:"GO:0009690"(cytokinin metabolic process)|go:"GO:0009723"(response to ethylene)|go:"GO:0009727"(detection of ethylene stimulus)|go:"GO:0009733"(response to auxin)|interpro:IPR036097|interpro:IPR036890	-	-	-	figure legend:Figure 1	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/07/03	2014/10/16	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	rogid:HU7HG7EHvZR/6trEt2M2wmFdHRY3702	intact-crc:EFAD3B0B9E11BD74|rigid:7FcGseyr1uWc5MzLvsd1Gg4uzGE	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)