#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9JM55 uniprotkb:P48281 intact:EBI-7859607|ensembl:ENSMUSP00000061390|intact:UNK-5550530 intact:EBI-346797|uniprotkb:Q922X0|ensembl:ENSMUSP00000023119 psi-mi:tob2_mouse(display_long)|uniprotkb:Tob2(gene name)|psi-mi:Tob2(display_short)|uniprotkb:Transducer of erbB-2 2(gene name synonym) psi-mi:vdr_mouse(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Ajima et al. (2008) pubmed:18358842|imex:IM-11547|mint:MINT-6504195 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7859601|mint:MINT-6504201|imex:IM-11547-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000048546(gene)|ensembl:ENSMUST00000050467(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045778"(positive regulation of ossification)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR015676(Transducer of ErbB-2)|interpro:IPR015678(Transducer of ErbB-2, 2)|interpro:IPR036054|mint:Q9JM55|refseq:NP_065253.1|mint:MINT-6504203(identity) refseq:NP_033530.2|dip:DIP-31478N|ensembl:ENSMUSG00000022479(gene)|ensembl:ENSMUST00000023119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P48281|reactome:R-MMU-196791|mint:MINT-6504204(identity) - comment:mint|function:Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases - figure legend:F5|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2008/04/08 2014/10/16 rogid:PmvfXglID6jzdJYfGKfl/HZZfP810090 rogid:AokMBDK0gDfmiuW3AwhWJO7mMgg10090 intact-crc:20DB27918D899C7A|rigid:3dKNZwCBOcFuV3TbxOFfPDKk7Jc false glutathione s tranferase tag:?-?(MINT-6504206) myc tag:?-?(MINT-6504211) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)