#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9U2C3 uniprotkb:G5ECW9 intact:EBI-7853654|intact:UNK-5998750|ensemblmetazoa:Y47D3A.25.1 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:q9u2c3_caeel(display_long)|uniprotkb:CELE_Y47D3A.25(orf name)|uniprotkb:rab-35(gene name)|psi-mi:rab-35(display_short)|uniprotkb:Y47D3A.25(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7853671|mint:MINT-6604060|imex:IM-11597-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8876198|mint:Q9U2C3|refseq:NP_499454.1|interpro:IPR001806(Ras GTPase)|wormbase:Y47D3A.25|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|ensemblmetazoa:WBGene00004284(gene)|ensemblmetazoa:Y47D3A.25.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071532"(ankyrin repeat binding)|reactome:R-CEL-8854214|reactome:R-CEL-8873719|interpro:IPR041815|mint:MINT-6604062(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604063(identity) - comment:mint - figure legend:f3e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/06/16 2014/10/16 rogid:2DDHJkKiJARmFgKtetNkOcNs5846239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:710D76992C78D1C5|rigid:dbTWhs54uiTIvr373iR1881by7M false tag:?-?(MINT-6604125) tag:?-?(MINT-6604121) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5ECW9 uniprotkb:Q22601 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3 psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name) psi-mi:"MI:0018"(two hybrid) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7853734|mint:MINT-6604204|imex:IM-11597-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604210(identity) interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)|mint:MINT-6604206(identity) - - - figure legend:f7a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/06/16 2014/10/16 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239 intact-crc:66E8414369B5E4E4|rigid:VTEtVPK24aM/G2f7Wo7l/Y1i4ps false tag:?-?(MINT-6604211) binding-associated region:682-925(MINT-6604219)|tag:?-?(MINT-6604207) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9U2C3 uniprotkb:G5ECW9 intact:EBI-7853654|intact:UNK-5998750|ensemblmetazoa:Y47D3A.25.1 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:q9u2c3_caeel(display_long)|uniprotkb:CELE_Y47D3A.25(orf name)|uniprotkb:rab-35(gene name)|psi-mi:rab-35(display_short)|uniprotkb:Y47D3A.25(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7853766|mint:MINT-6604129|imex:IM-11597-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8876198|mint:Q9U2C3|refseq:NP_499454.1|interpro:IPR001806(Ras GTPase)|wormbase:Y47D3A.25|interpro:IPR027417|interpro:IPR005225(Small GTP-binding protein)|ensemblmetazoa:WBGene00004284(gene)|ensemblmetazoa:Y47D3A.25.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071532"(ankyrin repeat binding)|reactome:R-CEL-8854214|reactome:R-CEL-8873719|interpro:IPR041815|mint:MINT-6604131(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604135(identity) - comment:mint - figure legend:f3f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2008/06/16 2014/10/16 rogid:2DDHJkKiJARmFgKtetNkOcNs5846239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:B2A4DD035C48A34E|rigid:dbTWhs54uiTIvr373iR1881by7M false ha tag:?-?(MINT-6604132)|mutation increasing interaction:24-24(MINT-6604143) green fluorescent protein tag:?-?(MINT-6604136) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q22601 uniprotkb:G5ECW9 intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7853789|mint:MINT-6604222|imex:IM-11597-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)|mint:MINT-6604224(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604230(identity) - - - figure legend:f7c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2008/06/16 2014/10/16 rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:31A1E38B46233740|rigid:VTEtVPK24aM/G2f7Wo7l/Y1i4ps false - green fluorescent protein tag:?-?(MINT-6604231) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:G5ECW9 uniprotkb:P34574 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7853870|mint:MINT-6604180|imex:IM-11597-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604183(identity) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N|mint:MINT-6604198(identity) go:"GO:0005938"(cell cortex) - - figure legend:f6|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-oocyte)|taxid:6239(Caenorhabditis elegans oocyte) - 2008/06/16 2014/10/16 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:3B83658A87F3216A|rigid:fkKAZfPcR4Nc0Y1/p+ohl/yK0Do false green fluorescent protein tag:?-?(MINT-6604184) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q22601 uniprotkb:G5ECW9 intact:EBI-5323248|ensemblmetazoa:T20B5.1.1|ensemblmetazoa:T20B5.1.2|ensemblmetazoa:T20B5.1.3 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:q22601_caeel(display_long)|uniprotkb:T20B5.1(orf name)|uniprotkb:apa-2(gene name)|psi-mi:apa-2(display_short)|uniprotkb:CELE_T20B5.1(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sato et al. (2008) pubmed:18354496|imex:IM-11597|mint:MINT-6604044 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7853897|mint:MINT-6604240|imex:IM-11597-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:Q22601|refseq:NP_509572.1|wormbase:T20B5.1|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|go:"GO:0006886"(intracellular protein transport)|ensemblmetazoa:T20B5.1.1(transcript)|ensemblmetazoa:T20B5.1.2(transcript)|ensemblmetazoa:T20B5.1.3(transcript)|ensemblmetazoa:WBGene00000161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0045202"(synapse)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-6798695|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|go:"GO:0008022"(protein C-terminus binding)|mint:MINT-6604242(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|mint:MINT-6604244(identity) - - - figure legend:f7b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2008/06/16 2014/10/16 rogid:h1D5aAR/42LZEGamNt9ibHcovUg6239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:39CF739D923B9619|rigid:VTEtVPK24aM/G2f7Wo7l/Y1i4ps false - green fluorescent protein tag:?-?(MINT-6604245) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)