#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50052 uniprotkb:P35625 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748097|imex:IM-20022-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 - - - figure legend:S1 A|author-identifiers:PREY gene NM_000686|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/03/25 2014/10/16 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 intact-crc:883E8146F963E3F4|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false sufficient binding region:210-363 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35625 uniprotkb:P50052 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748111|imex:IM-20022-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 - - - figure legend:S1 C|author-identifiers:PREY gene NM_000686|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/03/25 2014/10/16 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 intact-crc:92FB0D3E5D9606A6|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false sufficient binding region:1-144(IPR001134) sufficient binding region:235-363 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50052 uniprotkb:P35625 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748158|imex:IM-20022-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 - - - figure legend:1 A|author-identifiers:BAIT gene NM_000686|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/03/25 2014/10/16 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 intact-crc:3A47F9C45044329B|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50052 uniprotkb:P35625 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748121|imex:IM-20022-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 - - - figure legend:S1 B|author-identifiers:PREY gene NM_000686|delivery method:P50052; P35625 transfection|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/03/25 2014/10/16 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 intact-crc:C8954335D772B3D7|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false his tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50052 uniprotkb:P35625 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748143|imex:IM-20022-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 - - - figure legend:1 B|author-identifiers:PREY gene NM_000686|delivery method:P50052; P35625 transfection|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-skov_3)|taxid:9606(Homo sapiens ovarian adenocarcinoma cell line) - 2008/03/25 2014/10/16 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 intact-crc:A344DD0E37180AD6|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false his tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50052 uniprotkb:P35625 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1748173|imex:IM-20022-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 - - - figure legend:1 E|author-identifiers:BAIT gene NM_000686|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/03/25 2014/10/16 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 intact-crc:84A0442784CDFD14|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35625 uniprotkb:P50052 intact:EBI-1748085|uniprotkb:Q5THV4|uniprotkb:Q9UC74|uniprotkb:Q9UGS2|uniprotkb:B2RBY9|ensembl:ENSP00000266085 intact:EBI-1748067|uniprotkb:Q13016|uniprotkb:Q6FGY7|uniprotkb:B2R9V1|ensembl:ENSP00000360973|ensembl:ENSP00000505750 psi-mi:timp3_human(display_long)|uniprotkb:TIMP3(gene name)|psi-mi:TIMP3(display_short)|uniprotkb:Tissue inhibitor of metalloproteinases 3(gene name synonym)|uniprotkb:Protein MIG-5(gene name synonym) psi-mi:agtr2_human(display_long)|uniprotkb:AGTR2(gene name)|psi-mi:AGTR2(display_short)|uniprotkb:Angiotensin II type-2 receptor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kang et al. (2008) pubmed:18344519|imex:IM-20022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1749967|imex:IM-20022-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000353.1|ensembl:ENSG00000100234(gene)|ensembl:ENST00000266085(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007601"(visual perception)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0034097"(response to cytokine)|go:"GO:0046872"(metal ion binding)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1904684"(negative regulation of metalloendopeptidase activity)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001820(Proteinase inhibitor I35, tissue inhibitor of metalloproteinase)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR015612(Tissue inhibitor of metalloprotease 3)|interpro:IPR027465|interpro:IPR030490|rcsb pdb:3CKI|reactome:R-HSA-114608 refseq:NP_000677.2|refseq:XP_011535835.1|ensembl:ENSG00000180772(gene)|ensembl:ENST00000371906(transcript)|ensembl:ENST00000681852(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032304"(negative regulation of icosanoid secretion)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0035932"(aldosterone secretion)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042311"(vasodilation)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051387"(negative regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000147(AT2 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:6JOD|reactome:R-HSA-375276|reactome:R-HSA-418594 - - - figure legend:1 E|author-identifiers:PREY gene NM_000686|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/03/25 2014/10/16 rogid:PlxF7dY2tocdVIVz1s5j14mViqY9606 rogid:tXWI4w7l3DHAfmhthRZY9Hxrvus9606 intact-crc:2330ED238CCE6231|rigid:OhLncXwypged1nlZqqOCZDnz2Hw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)