#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q60809	uniprotkb:Q04211	intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933	intact:EBI-7847081|ensembl:ENSMUSP00000020692|intact:MINT-1517995	psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym)	psi-mi:btg2_mouse(display_long)|uniprotkb:Btg2(gene name)|psi-mi:Btg2(display_short)|uniprotkb:Tis21(gene name synonym)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible protein TIS21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mauxion et al. (2008)	pubmed:18337750|imex:IM-11581|mint:MINT-6544442	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7847076|mint:MINT-6544450|imex:IM-11581-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115|mint:MINT-6544452(identity)	ensembl:ENSMUSG00000020423(gene)|ensembl:ENSMUST00000020692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|interpro:IPR036054|mint:Q04211|rcsb pdb:3DJN|go:"GO:0017148"(negative regulation of translation)|reactome:R-MMU-6804115|refseq:NP_031596.1|dip:DIP-41601N|mint:MINT-6544453(identity)	-	-	comment:mint|function:Anti-proliferative protein. Modulates transcription regulation mediated by ESR1	figure legend:F3B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2008/05/20	2014/10/16	rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090	rogid:7BocM19zCEv3H2oW41XX6DMgaTY10090	intact-crc:ECBA24C156FEE071|rigid:rzVHNHSPzgDtLT6xOTOx4uaZG0g	false	glutathione s tranferase tag:?-?(MINT-6544459)	his tag:?-?(MINT-6544455)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q60809	uniprotkb:P78543	intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933	intact:EBI-1047576|uniprotkb:Q3KR25|uniprotkb:Q5VUT0|ensembl:ENSP00000290551|ensembl:ENSP00000433553|uniprotkb:A0A024R986	psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym)	psi-mi:btg2_human(display_long)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible anti-proliferative protein PC3(gene name synonym)|uniprotkb:BTG2(gene name)|psi-mi:BTG2(display_short)|uniprotkb:PC3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mauxion et al. (2008)	pubmed:18337750|imex:IM-11581|mint:MINT-6544442	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7847193|mint:MINT-6544467|imex:IM-11581-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115|mint:MINT-6544469(identity)	refseq:NP_006754.1|ensembl:ENST00000290551(transcript)|ensembl:ENST00000475157(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|mint:P78543|rcsb pdb:3DJU|rcsb pdb:3E9V|reactome:R-HSA-6804115|interpro:IPR036054|ensembl:ENSG00000159388(gene)|mint:MINT-6544473(identity)	-	-	-	figure legend:F3A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/05/20	2014/10/16	rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090	rogid:TV0Y3Baar0Ihame8uOI8vxg3Azs9606	intact-crc:453353A92C7B51BA|rigid:kaAQJsVn337yHVSTHixFuRJ7ASg	false	tag:?-?(MINT-6544470)	tag:?-?(MINT-6544474)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HBU9	uniprotkb:P78543	intact:EBI-7847235|uniprotkb:Q86UE7|intact:MINT-6544493|ensembl:ENSP00000264231	intact:EBI-1047576|uniprotkb:Q3KR25|uniprotkb:Q5VUT0|ensembl:ENSP00000290551|ensembl:ENSP00000433553|uniprotkb:A0A024R986	psi-mi:popd2_human(display_long)|uniprotkb:POPDC2(gene name)|psi-mi:POPDC2(display_short)|uniprotkb:POP2(gene name synonym)	psi-mi:btg2_human(display_long)|uniprotkb:BTG family member 2(gene name synonym)|uniprotkb:NGF-inducible anti-proliferative protein PC3(gene name synonym)|uniprotkb:BTG2(gene name)|psi-mi:BTG2(display_short)|uniprotkb:PC3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mauxion et al. (2008)	pubmed:18337750|imex:IM-11581|mint:MINT-6544442	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7847229|mint:MINT-6544482|imex:IM-11581-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001295262.1|refseq:NP_071418.2|ensembl:ENSG00000121577(gene)|ensembl:ENST00000264231(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030552"(cAMP binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0051146"(striated muscle cell differentiation)|interpro:IPR006916(Popeye protein conserved region)|interpro:IPR018490|mint:Q9HBU9|mint:MINT-6544488(identity)	refseq:NP_006754.1|ensembl:ENST00000290551(transcript)|ensembl:ENST00000475157(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006479"(protein methylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0031175"(neuron projection development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002087(Anti-proliferative protein)|interpro:IPR033328|interpro:IPR033332|mint:P78543|rcsb pdb:3DJU|rcsb pdb:3E9V|reactome:R-HSA-6804115|interpro:IPR036054|ensembl:ENSG00000159388(gene)|mint:MINT-6544484(identity)	-	function:May play an important role in heart development|comment:mint	-	figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/05/20	2014/10/16	rogid:FyaEwQAyais9H4Avz29C0WU1wHk9606	rogid:TV0Y3Baar0Ihame8uOI8vxg3Azs9606	intact-crc:401A300DE948F583|rigid:WIv+nEI0hkluj0MxS4sTBsifBUc	false	tag:?-?(MINT-6544489)	tag:?-?(MINT-6544485)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60809	uniprotkb:P51679	intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933	intact:EBI-7847466|ensembl:ENSP00000332659|uniprotkb:Q9ULY6|intact:MINT-1525168|uniprotkb:Q9ULY7	psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym)	psi-mi:ccr4_human(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:CMKBR4(gene name synonym)|uniprotkb:K5-5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mauxion et al. (2008)	pubmed:18337750|imex:IM-11581|mint:MINT-6544442	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7847460|mint:MINT-6544518|imex:IM-11581-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115|mint:MINT-6544524(identity)	ensembl:ENSG00000183813(gene)|ensembl:ENST00000330953(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002507"(tolerance induction)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009314"(response to radiation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0060326"(cell chemotaxis)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002239(C-C chemokine receptor, type 4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51679|reactome:R-HSA-380108|reactome:R-HSA-418594|interpro:IPR000276(GPCR, rhodopsin-like)|refseq:XP_016861176.1|refseq:NP_005499.1|dip:DIP-5848N|mint:MINT-6544520(identity)	-	-	comment:mint|function:"High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival"	figure legend:F4A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/05/20	2014/10/16	rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090	rogid:UDA9xqLRvwP7SKzO9kkKdKsyhjc9606	intact-crc:122493629C96889F|rigid:YJOpuHoT+RO0UHWo6IecKxhZWro	false	calmodulin binding peptide plus protein a tag:?-?(MINT-6544525)	green fluorescent protein tag:?-?(MINT-6544521)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)