#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7841175|mint:MINT-6178760|imex:IM-13977-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178763(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178762(identity) go:"GO:0030027"(lamellipodium) - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:57E7B2A15DC0F00C|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false - t7 tag:?-?(MINT-6178769) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O55222 uniprotkb:Q9HBI1 intact:EBI-6690138|uniprotkb:Q78KK2|ensembl:ENSMUSP00000033182|ensembl:ENSMUSP00000130341 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:ilk_mouse(display_long)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:Ilk(gene name)|psi-mi:Ilk(display_short) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7841191|mint:MINT-6178779|imex:IM-13977-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155196.1|refseq:NP_034692.2|ensembl:ENSMUSG00000030890(gene)|ensembl:ENSMUST00000033182(transcript)|ensembl:ENSMUST00000163389(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043034"(costamere)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:O55222|reactome:R-MMU-446343|reactome:R-MMU-446353|dip:DIP-41971N|mint:MINT-6178786(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178782(identity) go:"GO:0030027"(lamellipodium) - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:9kMagkwUrtq1XaI+9PXPJ21hHY810090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:2BA02E54DB933677|rigid:E5udrp2DO0vnPSfhnvpYvJTcnDs false - t7 tag:?-?(MINT-6178783) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9ESD7 uniprotkb:Q9HBI1 intact:EBI-7031166|ensembl:ENSMUSP00000132297|uniprotkb:Q80VT0|uniprotkb:Q9QXC0|uniprotkb:Q6KAR3|intact:MINT-274938 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:dysf_mouse(display_long)|uniprotkb:Dysf(gene name)|psi-mi:Dysf(display_short)|uniprotkb:Fer1l1(gene name synonym)|uniprotkb:Dystrophy-associated fer-1-like protein(gene name synonym)|uniprotkb:Fer-1-like protein 1(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7841262|mint:MINT-6178801|imex:IM-13977-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001071162.1|refseq:NP_001297081.1|ensembl:ENSMUSG00000033788(gene)|ensembl:ENSMUST00000168387(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002280"(monocyte activation involved in immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042383"(sarcolemma)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0055001"(muscle cell development)|go:"GO:0061025"(membrane fusion)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098857"(membrane microdomain)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029998|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q9ESD7|reactome:R-MMU-445355|refseq:NP_067444.2|mint:MINT-6178808(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178804(identity) go:"GO:0030027"(lamellipodium) comment:mint|function:Defects in Dysf are the cause of a slowly progressive muscular dystrophy observed in SJL mice. It affects primarily the proximal muscles and it is inherited as autosomal recessive trait - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:3BBj/3m+gTLqU0VMG6RY+5Ov5Yk10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:704766B618D220E0|rigid:i4pmyyjrQDp69hsktBML8/sVr8U false - t7 tag:?-?(MINT-6178805) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8K4I3 uniprotkb:Q9HBI1 intact:EBI-6272809|uniprotkb:Q8C9V4 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg6_mouse(display_long)|uniprotkb:Alpha-PIX(gene name synonym)|uniprotkb:Arhgef6(gene name)|psi-mi:Arhgef6(display_short)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7841207|mint:MINT-6178790|imex:IM-13977-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005911"(cell-cell junction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0035556"(intracellular signal transduction)|rcsb pdb:1V61|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-446388|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013420|interpro:IPR032409|mint:Q8K4I3|refseq:NP_690014.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|interpro:IPR003096(SM22/calponin)|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178797(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178793(identity) go:"GO:0030027"(lamellipodium) - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:3qsyAQpus/hb/97AanKkOKb7+uI10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:AE65FE029594F096|rigid:DsHnxsUV//xSVVVs0TNwKKTIgqU false - t7 tag:?-?(MINT-6178794) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841307|mint:MINT-6178812|imex:IM-13977-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178819(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178815(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:921BA9D032D1DFBF|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false - t7 tag:?-?(MINT-6178816) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8K4I3 uniprotkb:Q9HBI1 intact:EBI-6272809|uniprotkb:Q8C9V4 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg6_mouse(display_long)|uniprotkb:Alpha-PIX(gene name synonym)|uniprotkb:Arhgef6(gene name)|psi-mi:Arhgef6(display_short)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841337|mint:MINT-6178843|imex:IM-13977-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005911"(cell-cell junction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0035556"(intracellular signal transduction)|rcsb pdb:1V61|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-446388|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013420|interpro:IPR032409|mint:Q8K4I3|refseq:NP_690014.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|interpro:IPR003096(SM22/calponin)|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178849(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178845(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:3qsyAQpus/hb/97AanKkOKb7+uI10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:82D7FB7DF49752E2|rigid:DsHnxsUV//xSVVVs0TNwKKTIgqU false - t7 tag:?-?(MINT-6178846) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841322|mint:MINT-6178832|imex:IM-13977-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178838(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178834(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:D3301321EBC68824|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false - t7 tag:?-?(MINT-6178835) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841619|mint:MINT-6179212|imex:IM-13977-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6179218(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6179214(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:EBB2B25CF7224500|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841607|mint:MINT-6179203|imex:IM-13977-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6179209(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6179205(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:1B16B4D961224095|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HBI1 uniprotkb:Q8K4I3 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 intact:EBI-6272809|uniprotkb:Q8C9V4 psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:arhg6_mouse(display_long)|uniprotkb:Alpha-PIX(gene name synonym)|uniprotkb:Arhgef6(gene name)|psi-mi:Arhgef6(display_short)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841631|mint:MINT-6179221|imex:IM-13977-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6179223(identity) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005911"(cell-cell junction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0035556"(intracellular signal transduction)|rcsb pdb:1V61|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-446388|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013420|interpro:IPR032409|mint:Q8K4I3|refseq:NP_690014.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|interpro:IPR003096(SM22/calponin)|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6179227(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2008/02/13 2014/10/16 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 rogid:3qsyAQpus/hb/97AanKkOKb7+uI10090 intact-crc:7847169AAC79E797|rigid:DsHnxsUV//xSVVVs0TNwKKTIgqU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841364|mint:MINT-6178859|imex:IM-13977-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178865(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178861(identity) - - - figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:F5A29A5341FAE2ED|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false ha tag:?-?(MINT-6178869) binding-associated region:53-212(MINT-6178912)|t7 tag:?-?(MINT-6178862) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841428|mint:MINT-6178962|imex:IM-13977-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178971(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178964(identity) - - - figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:80E9AA7362F746DF|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false glutathione s tranferase tag:?-?(MINT-6178972)|binding-associated region:93-273(MINT-6178979) t7 tag:?-?(MINT-6178968) - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7841495|mint:MINT-6179002|imex:IM-13977-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6179008(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6179004(identity) - - - figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:0F8FEE8DEB79E8C1|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false binding-associated region:93-273(MINT-6179011)|glutathione s tranferase tag:?-?(MINT-6179009) binding-associated region:53-212(MINT-6179017) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9HBI1 uniprotkb:Q9ES28 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841464|mint:MINT-6178983|imex:IM-13977-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6178985(identity) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6178989(identity) - - - figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 intact-crc:C31D7373C32ED0BC|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false t7 tag:?-?(MINT-6178986) binding-associated region:295-400(MINT-6178992)|glutathione s tranferase tag:?-?(MINT-6178990) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q13153 uniprotkb:P63001 intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696 intact:EBI-413646|ensembl:ENSMUSP00000079380|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q9BTB4 psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym) psi-mi:rac1_mouse(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:p21-Rac1(gene name synonym) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841565|mint:MINT-6179039|imex:IM-13977-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|mint:MINT-6179041(identity) go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003382"(epithelial cell morphogenesis)|ensembl:ENSMUSG00000001847(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|ensembl:ENSMUST00000080537(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0001891"(phagocytic cup)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0007411"(axon guidance)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021831"(embryonic olfactory bulb interneuron precursor migration)|go:"GO:0021894"(cerebral cortex GABAergic interneuron development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042470"(melanosome)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048532"(anatomical structure arrangement)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060091"(kinocilium)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:2000386"(positive regulation of ovarian follicle development)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|interpro:IPR027417|mint:P63001|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|interpro:IPR005225(Small GTP-binding protein)|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-376172|reactome:R-MMU-389359|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-399954|reactome:R-MMU-4086400|reactome:R-MMU-416550|reactome:R-MMU-5663213|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-5663220|reactome:R-MMU-5668599|reactome:R-MMU-5687128|reactome:R-MMU-6798695|reactome:R-MMU-445144|reactome:R-MMU-6811558|reactome:R-MMU-8849471|reactome:R-MMU-8875555|reactome:R-MMU-9013149|reactome:R-MMU-9032759|reactome:R-MMU-983231|reactome:R-MMU-5218920|reactome:R-MMU-5625740|reactome:R-MMU-5625900|reactome:R-MMU-5625970|reactome:R-MMU-5626467|reactome:R-MMU-5627123|refseq:NP_033033.1|dip:DIP-31545N|mint:MINT-6179042(identity) - - - figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A10090 intact-crc:33E43372C27E463E|rigid:AyecYl76GFAhdiScUknxUYn53ww false glutathione s tranferase tag:?-?(MINT-6179044)|binding-associated region:67-150(MINT-6179046) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ES28 uniprotkb:Q9HBI1 intact:EBI-642580|uniprotkb:O08757|uniprotkb:Q3UTS5|uniprotkb:Q6XPA5|uniprotkb:Q6ZQI5|uniprotkb:Q8C750|uniprotkb:Q91ZZ6|uniprotkb:Q9ES27 intact:EBI-1047679|uniprotkb:Q5TGJ5|uniprotkb:Q86X93|uniprotkb:Q9NSP7|uniprotkb:Q9UGT3|uniprotkb:Q9Y368|uniprotkb:Q9Y3L6|uniprotkb:Q9Y3L7|uniprotkb:B0QYM8|uniprotkb:B2R9X6|uniprotkb:B0QYN1|uniprotkb:Q96PN1|ensembl:ENSP00000342492 psi-mi:arhg7_mouse(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:p85SPR(gene name synonym)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym) psi-mi:parvb_human(display_long)|uniprotkb:Affixin(gene name synonym)|uniprotkb:PARVB(gene name)|psi-mi:PARVB(display_short)|uniprotkb:CGI-56(orf name) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7841537|mint:MINT-6179021|imex:IM-13977-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001106989.1|refseq:NP_001106990.1|refseq:NP_059098.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001452(Src homology-3)|refseq:XP_006508906.2|refseq:XP_006508907.2|interpro:IPR032409|refseq:XP_006508904.2|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|rcsb pdb:2ESW|rcsb pdb:6JMT|reactome:R-MMU-182971|reactome:R-MMU-193648|reactome:R-MMU-3928664|mint:Q9ES28|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:MINT-6179030(identity) refseq:NP_001003828.1|refseq:NP_037459.2|refseq:NP_001230315.1|refseq:NP_001230314.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9HBI1|rcsb pdb:4EDL|rcsb pdb:4EDM|rcsb pdb:4EDN|reactome:R-HSA-446353|reactome:R-HSA-446388|ensembl:ENSG00000188677(gene)|ensembl:ENST00000338758(transcript)|go:"GO:0003779"(actin binding)|mint:MINT-6179023(identity) - - - figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:+Bie+UoaAI9/ldibUxAjNYc3sYs10090 rogid:TgzllMJYQ4Ex1Mgc7Kuk1SdrrR89606 intact-crc:6BF22CFD296D9CD1|rigid:qTp98iRLBdl2fF1tdUsb2eiHdBk false binding-associated region:295-400(MINT-6179031)|glutathione s tranferase tag:?-?(MINT-6179034) binding-associated region:53-212(MINT-6179024)|his tag:?-?(MINT-6179027) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13153 uniprotkb:P60766 intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696 intact:EBI-81763|ensembl:ENSMUSP00000054634|uniprotkb:A2A9U6|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q3THZ7|uniprotkb:Q3TJK6|uniprotkb:Q545V0|uniprotkb:Q6P201|uniprotkb:Q8BQ51 psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym) psi-mi:cdc42_mouse(display_long)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Matsuda et al. (2008) pubmed:18325335|imex:IM-13977|mint:MINT-6178739|doi:10.1016/j.febslet.2008.01.064 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7841586|mint:MINT-6179054|imex:IM-13977-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|mint:MINT-6179056(identity) ensembl:ENSMUSG00000006699(gene)|ensembl:ENSMUST00000051477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|refseq:NP_033991.1|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043209"(myelin sheath)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051647"(nucleus localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071944"(cell periphery)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60766|rcsb pdb:3EG5|rcsb pdb:5C2J|reactome:R-MMU-114604|reactome:R-MMU-182971|reactome:R-MMU-2029482|reactome:R-MMU-389359|reactome:R-MMU-3928662|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-525793|reactome:R-MMU-5625970|reactome:R-MMU-5626467|reactome:R-MMU-5627123|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-983231|go:"GO:0048664"(neuron fate determination)|refseq:NP_001230698.1|dip:DIP-32554N|mint:MINT-6179063(identity) - - - figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/13 2014/10/16 rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU10090 intact-crc:B9006EB2E7583745|rigid:jv8dpBnpyK2fedEVjp0rLyqszQ0 false binding-associated region:67-150(MINT-6179057)|glutathione s tranferase tag:?-?(MINT-6179060) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)