#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70032	uniprotkb:Q91876	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824752|mint:MINT-6540571|imex:IM-11561-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540573(identity)	go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562|mint:MINT-6540574(identity)	-	-	-	figure legend:F5C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-)|taxid:8355(Xenopus laevis)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355	intact-crc:AF9661C3AB515A33|rigid:EqpYgX5PJ3fQjBFxJy3DfHx9KIk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0709"(polyclonal antibody immunostaining)
uniprotkb:P70032	uniprotkb:Q91876	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym)	psi-mi:"MI:0096"(pull down)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824773|mint:MINT-6540580|imex:IM-11561-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540582(identity)	go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562|mint:MINT-6540584(identity)	go:"GO:0005634"(nucleus)	-	-	figure legend:F5E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355	intact-crc:5FC127C8AE4DA52C|rigid:EqpYgX5PJ3fQjBFxJy3DfHx9KIk	false	glutathione s tranferase tag:?-?(MINT-6540594)|binding-associated region:411-578(MINT-6540596)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P70032	uniprotkb:Q498J7	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-7824798|intact:MINT-6540683|uniprotkb:Q6AZF4|uniprotkb:O73711	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mc6za_xenla(display_long)|uniprotkb:zmcm6-a(gene name)|psi-mi:zmcm6-a(display_short)|uniprotkb:Zygotic minichromosome maintenance protein 6-A(gene name synonym)|uniprotkb:zmcm6a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824793|mint:MINT-6540600|imex:IM-11561-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540605(identity)	interpro:IPR033762|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|mint:Q498J7|interpro:IPR031327|interpro:IPR027417|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR008049(MCM protein 6)|refseq:NP_001131039.1|interpro:IPR027925|interpro:IPR041024|interpro:IPR041562|mint:MINT-6540695(identity)	-	-	function:Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. The mcm2-mcm7 complex has ATPase activity, which is dispensable for assembly of the pre-replicative complex onto chromatin, but is required for DNA unwinding|comment:mint	figure legend:F5D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:pkcC86VwMKxb28xBFitQaBJOuvI8355	intact-crc:48A62BCE3EFE0EC3|rigid:YihmdHB8VcqdefldDE3OuhMAokM	false	glutathione s tranferase tag:?-?(MINT-6540609)|binding-associated region:411-578(MINT-6540606)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P70032	uniprotkb:Q5XK83	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-1789370|uniprotkb:O42589	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mcm4a_xenla(display_long)|uniprotkb:mcm4-a(gene name)|psi-mi:mcm4-a(display_short)|uniprotkb:Minichromosome maintenance protein 4-A(gene name synonym)|uniprotkb:CDC21 homolog-A(gene name synonym)|uniprotkb:P1-CDC21-A(gene name synonym)|uniprotkb:p98(gene name synonym)	psi-mi:"MI:0096"(pull down)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824793|mint:MINT-6540600|imex:IM-11561-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540605(identity)	interpro:IPR033762|refseq:NP_001079069.1|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027925|interpro:IPR027417|mint:Q5XK83|interpro:IPR041562|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|mint:MINT-6540682(identity)	-	-	-	figure legend:F5D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:VBIiuJghubSRemwMGVBc8alovhI8355	intact-crc:48A62BCE3EFE0EC3|rigid:YihmdHB8VcqdefldDE3OuhMAokM	false	glutathione s tranferase tag:?-?(MINT-6540609)|binding-associated region:411-578(MINT-6540606)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P70032	uniprotkb:Q91876	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-876852|uniprotkb:O42591|uniprotkb:Q6GQ16	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mcm7a_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 7-A(gene name synonym)|uniprotkb:CDC47 homolog A(gene name synonym)|uniprotkb:CDC47p(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:mcm7-a(gene name)|psi-mi:mcm7-a(display_short)|uniprotkb:cdc47(gene name synonym)	psi-mi:"MI:0096"(pull down)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824793|mint:MINT-6540600|imex:IM-11561-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540605(identity)	go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR027925|refseq:NP_001081466.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:Q91876|interpro:IPR041562|mint:MINT-6540603(identity)	-	-	-	figure legend:F5D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:IPLvcG4PDdfeYmVQhOOHEVSG1+s8355	intact-crc:48A62BCE3EFE0EC3|rigid:YihmdHB8VcqdefldDE3OuhMAokM	false	glutathione s tranferase tag:?-?(MINT-6540609)|binding-associated region:411-578(MINT-6540606)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P70032	uniprotkb:P55861	intact:EBI-3511304|uniprotkb:Q7ZWQ6	intact:EBI-876864|uniprotkb:O42588|uniprotkb:Q7ZX05	psi-mi:plk1_xenla(display_long)|uniprotkb:plx1(gene name synonym)|uniprotkb:Plx1(gene name synonym)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)	psi-mi:mcm2_xenla(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:BM28-homolog(gene name synonym)|uniprotkb:p112(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)	psi-mi:"MI:0096"(pull down)	Trenz et al. (2008)	pubmed:18309293|imex:IM-11561|mint:MINT-6540543	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824793|mint:MINT-6540600|imex:IM-11561-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P70032|dip:DIP-42603N|refseq:NP_001080788.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051233"(spindle midzone)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:MINT-6540605(identity)	go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR027925|refseq:NP_001080759.1|interpro:IPR008045(MCM protein 2)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR027417|interpro:IPR033762|mint:P55861|interpro:IPR041562|mint:MINT-6540627(identity)	-	-	-	figure legend:F5D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/07	2014/10/16	rogid:4gWZeyS6h0rrULNgKgIufsQ/bLM8355	rogid:BKavzWA0OlaUmzbdJtq74Bk9qKM8355	intact-crc:48A62BCE3EFE0EC3|rigid:YihmdHB8VcqdefldDE3OuhMAokM	false	glutathione s tranferase tag:?-?(MINT-6540609)|binding-associated region:411-578(MINT-6540606)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0658"(multidimensional protein identification technology)