#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9U2Q9 uniprotkb:Q17941 intact:EBI-330089|uniprotkb:Q9Y0C2|ensemblmetazoa:Y18D10A.5.1 intact:EBI-1770718|uniprotkb:Q17942|uniprotkb:Q8MQE0|ensemblmetazoa:C12D8.10a.1|ensemblmetazoa:C12D8.10a.2 psi-mi:gsk3_caeel(display_long)|uniprotkb:gsk-3(gene name)|psi-mi:gsk-3(display_short)|uniprotkb:sgg-1(gene name synonym)|uniprotkb:Y18D10A.5(orf name) psi-mi:akt1_caeel(display_long)|uniprotkb:akt-1(gene name)|psi-mi:akt-1(display_short)|uniprotkb:C12D8.10(orf name)|uniprotkb:Protein kinase B akt-1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7823016|mint:MINT-6543398|imex:IM-11575-9 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493243.1|wormbase:Y18D10A.5|mint:Q9U2Q9|dip:DIP-25216N|ensemblmetazoa:WBGene00001746(gene)|ensemblmetazoa:Y18D10A.5.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0070986"(left/right axis specification)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-CEL-195253|reactome:R-CEL-196299|reactome:R-CEL-3371453|reactome:R-CEL-399956|reactome:R-CEL-4641262|mint:MINT-6543401(identity) refseq:NP_001023645.1|refseq:NP_001023646.1|refseq:NP_001023647.1|wormbase:C12D8.10a|wormbase:C12D8.10b|wormbase:C12D8.10c|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR039026|mint:Q17941|ensemblmetazoa:C12D8.10a.1(transcript)|ensemblmetazoa:C12D8.10a.2(transcript)|ensemblmetazoa:WBGene00000102(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902074"(response to salt)|reactome:R-CEL-1257604|reactome:R-CEL-1474151|reactome:R-CEL-165158|reactome:R-CEL-165159|reactome:R-CEL-198323|reactome:R-CEL-198693|reactome:R-CEL-199418|reactome:R-CEL-203615|reactome:R-CEL-211163|reactome:R-CEL-389357|reactome:R-CEL-389513|reactome:R-CEL-392451|reactome:R-CEL-450385|reactome:R-CEL-450604|reactome:R-CEL-5218920|reactome:R-CEL-6811558|reactome:R-CEL-69202|reactome:R-CEL-69656|reactome:R-CEL-8849469|reactome:R-CEL-8876198|reactome:R-CEL-8948751|reactome:R-CEL-9009391|reactome:R-CEL-9604323|reactome:R-CEL-9607240|reactome:R-CEL-9614399|reactome:R-CEL-9634638|mint:MINT-6543400(identity) - - - figure legend:f4a sf4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/05/19 2014/10/16 rogid:nP6ix+jIij252trr3joE6r80xYo6239 rogid:Lbru/j15mbtFfQv0kZ3xFS+32Hs6239 intact-crc:6B1FDF3918E9CC3D|rigid:tWWOoKZp2GakzC2jDEAAz/D7KEM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EFM0 uniprotkb:Q17941 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 intact:EBI-1770718|uniprotkb:Q17942|uniprotkb:Q8MQE0|ensemblmetazoa:C12D8.10a.1|ensemblmetazoa:C12D8.10a.2 psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:akt1_caeel(display_long)|uniprotkb:akt-1(gene name)|psi-mi:akt-1(display_short)|uniprotkb:C12D8.10(orf name)|uniprotkb:Protein kinase B akt-1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7822991|mint:MINT-6543392|imex:IM-11575-7 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543394(identity) refseq:NP_001023645.1|refseq:NP_001023646.1|refseq:NP_001023647.1|wormbase:C12D8.10a|wormbase:C12D8.10b|wormbase:C12D8.10c|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR039026|mint:Q17941|ensemblmetazoa:C12D8.10a.1(transcript)|ensemblmetazoa:C12D8.10a.2(transcript)|ensemblmetazoa:WBGene00000102(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902074"(response to salt)|reactome:R-CEL-1257604|reactome:R-CEL-1474151|reactome:R-CEL-165158|reactome:R-CEL-165159|reactome:R-CEL-198323|reactome:R-CEL-198693|reactome:R-CEL-199418|reactome:R-CEL-203615|reactome:R-CEL-211163|reactome:R-CEL-389357|reactome:R-CEL-389513|reactome:R-CEL-392451|reactome:R-CEL-450385|reactome:R-CEL-450604|reactome:R-CEL-5218920|reactome:R-CEL-6811558|reactome:R-CEL-69202|reactome:R-CEL-69656|reactome:R-CEL-8849469|reactome:R-CEL-8876198|reactome:R-CEL-8948751|reactome:R-CEL-9009391|reactome:R-CEL-9604323|reactome:R-CEL-9607240|reactome:R-CEL-9614399|reactome:R-CEL-9634638|mint:MINT-6543395(identity) - - - figure legend:f4a sf6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/05/19 2014/10/16 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 rogid:Lbru/j15mbtFfQv0kZ3xFS+32Hs6239 intact-crc:995C2CEF54BDF645|rigid:oHDi+0D+ySFzewx870AeWP1l6VE false binding-associated region:512-531(MINT-6543488)|mutation disrupting interaction:523-523(MINT-6543492)|phosphorylated residue:523-523(MINT-6543490) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q17941 uniprotkb:G5EFM0 intact:EBI-1770718|uniprotkb:Q17942|uniprotkb:Q8MQE0|ensemblmetazoa:C12D8.10a.1|ensemblmetazoa:C12D8.10a.2 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 psi-mi:akt1_caeel(display_long)|uniprotkb:akt-1(gene name)|psi-mi:akt-1(display_short)|uniprotkb:C12D8.10(orf name)|uniprotkb:Protein kinase B akt-1(gene name synonym) psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:"MI:0424"(protein kinase assay) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7823027|mint:MINT-6543497|imex:IM-11575-8 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023645.1|refseq:NP_001023646.1|refseq:NP_001023647.1|wormbase:C12D8.10a|wormbase:C12D8.10b|wormbase:C12D8.10c|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017892|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR039026|mint:Q17941|ensemblmetazoa:C12D8.10a.1(transcript)|ensemblmetazoa:C12D8.10a.2(transcript)|ensemblmetazoa:WBGene00000102(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902074"(response to salt)|reactome:R-CEL-1257604|reactome:R-CEL-1474151|reactome:R-CEL-165158|reactome:R-CEL-165159|reactome:R-CEL-198323|reactome:R-CEL-198693|reactome:R-CEL-199418|reactome:R-CEL-203615|reactome:R-CEL-211163|reactome:R-CEL-389357|reactome:R-CEL-389513|reactome:R-CEL-392451|reactome:R-CEL-450385|reactome:R-CEL-450604|reactome:R-CEL-5218920|reactome:R-CEL-6811558|reactome:R-CEL-69202|reactome:R-CEL-69656|reactome:R-CEL-8849469|reactome:R-CEL-8876198|reactome:R-CEL-8948751|reactome:R-CEL-9009391|reactome:R-CEL-9604323|reactome:R-CEL-9607240|reactome:R-CEL-9614399|reactome:R-CEL-9634638|mint:MINT-6543507(identity) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543499(identity) - - - figure legend:f4a sf6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/05/19 2014/10/16 rogid:Lbru/j15mbtFfQv0kZ3xFS+32Hs6239 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 intact-crc:F411BFB3023A6802|rigid:oHDi+0D+ySFzewx870AeWP1l6VE false - binding-associated region:?-?(MINT-6543504)|mutation disrupting interaction:672-672(MINT-6543500)|phosphorylated residue:672-672(MINT-6543502) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EFM0 uniprotkb:Q9NGT3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:"MI:0018"(two hybrid) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823082|mint:MINT-6543386|imex:IM-11575-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543389(identity) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543388(identity) - - - figure legend:f4e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/05/19 2014/10/16 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 intact-crc:BD4002553D5C1EA2|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false tag:?-?(MINT-6543525)|mutation disrupting interaction:523-523(MINT-6543528) tag:?-?(MINT-6543532) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NGT3 uniprotkb:G5EFM0 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:"MI:0018"(two hybrid) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823154|mint:MINT-6543550|imex:IM-11575-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543558(identity) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543552(identity) - - - figure legend:f4e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/05/19 2014/10/16 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 intact-crc:82B8FBEA9DA91302|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false tag:?-?(MINT-6543559) mutation decreasing interaction:523-523,672-672(MINT-6543553)|tag:?-?(MINT-6543555) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NGT3 uniprotkb:G5EFM0 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:"MI:0018"(two hybrid) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823132|mint:MINT-6543536|imex:IM-11575-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543538(identity) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543542(identity) - - - figure legend:f4e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/05/19 2014/10/16 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 intact-crc:C429A850FF0882B9|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false tag:?-?(MINT-6543539) mutation increasing interaction:523-523(MINT-6543543)|tag:?-?(MINT-6543545) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EFM0 uniprotkb:Q9NGT3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:"MI:0018"(two hybrid) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823203|mint:MINT-6543583|imex:IM-11575-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543585(identity) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543591(identity) - - - figure legend:f4e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/05/19 2014/10/16 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 intact-crc:91DC503E312FF126|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false mutation decreasing interaction:672-672(MINT-6543586)|tag:?-?(MINT-6543588) tag:?-?(MINT-6543592) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NGT3 uniprotkb:G5EFM0 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:"MI:0018"(two hybrid) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823181|mint:MINT-6543567|imex:IM-11575-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543569(identity) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543573(identity) - - - figure legend:f4e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2008/05/19 2014/10/16 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 intact-crc:324403B94532B2BC|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false tag:?-?(MINT-6543570) tag:?-?(MINT-6543578)|mutation with no effect:672-672(MINT-6543574) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NGT3 uniprotkb:G5EFM0 intact:EBI-328699|ensemblmetazoa:Y69A2AR.30a.1|ensemblmetazoa:Y69A2AR.30a.2|ensemblmetazoa:Y69A2AR.30a.3 intact:EBI-316684|ensemblmetazoa:C50F4.11.1 psi-mi:q9ngt3_caeel(display_long)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:g5efm0_caeel(display_long)|uniprotkb:mdf-1(gene name)|psi-mi:mdf-1(display_short)|uniprotkb:C50F4.11(orf name)|uniprotkb:CELE_C50F4.11(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Watanabe et al. (2008) pubmed:18309291|imex:IM-11575|mint:MINT-6543367 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7823236|mint:MINT-6543382|imex:IM-11575-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023563.1|wormbase:Y69A2AR.30a|dip:DIP-26793N|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-CEL-141405|reactome:R-CEL-141430|ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30a.1(transcript)|ensemblmetazoa:Y69A2AR.30a.2(transcript)|ensemblmetazoa:Y69A2AR.30a.3(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|mint:Q9NGT3|mint:MINT-6543385(identity) uniprotkb:Q9NGT4(uniprot-removed-ac)|mint:G5EFM0|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_505462.1|wormbase:C50F4.11|ensemblmetazoa:C50F4.11.1(transcript)|ensemblmetazoa:WBGene00003160(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|mint:MINT-6543384(identity) - - - figure legend:f4d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-larva)|taxid:6239(Immature form of the adult worm) - 2008/05/19 2014/10/16 rogid:YkqOAnk1TDTVg/syEOotdnoWQ9Q6239 rogid:UNzmKihtVrZ+kMLURzkODNOCidI6239 intact-crc:F561BCAE07C982DA|rigid:1ft3Bo90zRtPBk6bQ89eqXVO0Wk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)