#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62495 uniprotkb:P15170 intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7801134|mint:MINT-6539753|imex:IM-11555-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-6539755(identity) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1|mint:MINT-6539766(identity) - - - figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 intact-crc:824D22B556667AE1|rigid:7yfK56E8QB88R/tv5CFEyGFUPFw false flag tag:?-?(MINT-6539758) v5 tag:?-?(MINT-6539767) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62495 uniprotkb:Q92900 intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7801134|mint:MINT-6539753|imex:IM-11555-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-6539755(identity) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539756(identity) - - - figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:824D22B556667AE1|rigid:7yfK56E8QB88R/tv5CFEyGFUPFw false flag tag:?-?(MINT-6539758) v5 tag:?-?(MINT-6539762) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P15170 uniprotkb:Q92900 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801176|mint:MINT-6539771|imex:IM-11555-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1|mint:MINT-6539773(identity) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539777(identity) - - - figure legend:F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:941028CE2A3293F2|rigid:Mnxe+vmPQSy1pd5kWWz+zjbjQGY false flag tag:?-?(MINT-6539774)|binding-associated region:200-450(MINT-6539789) v5 tag:?-?(MINT-6539778) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P11940 uniprotkb:P15170 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801198|mint:MINT-6539792|imex:IM-11555-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N|mint:MINT-6539800(identity) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1|mint:MINT-6539794(identity) - - - figure legend:F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 intact-crc:E0D112C6D9EB3531|rigid:FT2LSlQBYQQwOWNgc900W6fScs0 false v5 tag:?-?(MINT-6539801) binding-associated region:1-200(MINT-6539795)|flag tag:?-?(MINT-6539797) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62495 uniprotkb:P15170 intact:EBI-750990|intact:EBI-1047744|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|ensembl:ENSP00000353741 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:erf1_human(display_long)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801220|mint:MINT-6539807|imex:IM-11555-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004721.1|refseq:NP_001243231.1|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|ensembl:ENSG00000120705(gene)|ensembl:ENST00000360541(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:0043022"(ribosome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR024049|interpro:IPR029064|interpro:IPR042226|mint:P62495|rcsb pdb:1DT9|rcsb pdb:2HST|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:2MQ6|rcsb pdb:2MQ9|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|rcsb pdb:5LZT|rcsb pdb:5LZU|rcsb pdb:5LZV|rcsb pdb:6D90|rcsb pdb:6IP8|rcsb pdb:6XA1|rcsb pdb:6ZME|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|mint:MINT-6539809(identity) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1|mint:MINT-6539813(identity) - - - figure legend:F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 intact-crc:41A9C183FBC7DDAF|rigid:otY7vxMHvTdCYV3mXIPgpNcSeXk false v5 tag:?-?(MINT-6539810) flag tag:?-?(MINT-6539814) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P15170 uniprotkb:Q92900 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801277|mint:MINT-6539822|imex:IM-11555-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1|mint:MINT-6539824(identity) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539830(identity) - - - figure legend:F4B F4C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:8B51B43ED9C76568|rigid:Mnxe+vmPQSy1pd5kWWz+zjbjQGY false v5 tag:?-?(MINT-6539827) binding-associated region:130-250(MINT-6539836)|flag tag:?-?(MINT-6539831) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92900 uniprotkb:Q9HAU5 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801372|mint:MINT-6539859|imex:IM-11555-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539863(identity) ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|mint:MINT-6539861(identity) - - - figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606 intact-crc:8B19F605D37254B3|rigid:mUc5BIzglRjKV98XLq4MJQ06Qh8 false mutation disrupting interaction:184-184(MINT-6539879)|mutation disrupting interaction:181-181(MINT-6539864)|mutation disrupting interaction:182-182(MINT-6539873)|binding-associated region:1-1073(MINT-6539868)|mutation disrupting interaction:183-183(MINT-6539876)|flag tag:?-?(MINT-6539866) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9HAU5 uniprotkb:Q92900 intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801322|mint:MINT-6539840|imex:IM-11555-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|mint:MINT-6539842(identity) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539846(identity) - - - figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:287C6C9762605E37|rigid:mUc5BIzglRjKV98XLq4MJQ06Qh8 false - flag tag:?-?(MINT-6539849)|mutation disrupting interaction:126-126(MINT-6539854)|binding-associated region:1-1073(MINT-6539847) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92900 uniprotkb:Q9HAU5 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7801437|mint:MINT-6539883|imex:IM-11555-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539885(identity) ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|mint:MINT-6539899(identity) - - - figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606 intact-crc:DFCAD5F22C29B55F|rigid:mUc5BIzglRjKV98XLq4MJQ06Qh8 false mutation disrupting interaction:204-204(MINT-6539886)|mutation disrupting interaction:205-205(MINT-6539888)|binding-associated region:1-1073(MINT-6539892)|flag tag:?-?(MINT-6539894) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96Q15 uniprotkb:Q9HAU5 intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515 intact:EBI-372073|uniprotkb:A6NLJ5|uniprotkb:Q5W0J4|uniprotkb:Q14BM1|uniprotkb:Q8N8U1|uniprotkb:Q9H1J2|uniprotkb:Q9NWL1|uniprotkb:Q9P2D9|uniprotkb:Q9Y4M9|uniprotkb:D3DRS0|intact:EBI-28979373|ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244 psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym) psi-mi:rent2_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:UPF2(gene name)|psi-mi:UPF2(display_short)|uniprotkb:KIAA1408(gene name synonym)|uniprotkb:RENT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7801538|mint:MINT-6539908|imex:IM-11555-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)|mint:MINT-6539927(identity) ensembl:ENSP00000348708|ensembl:ENSP00000350221|ensembl:ENSP00000380244|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENSG00000151461(gene)|ensembl:ENST00000356352(transcript)|ensembl:ENST00000357604(transcript)|ensembl:ENST00000397053(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|mint:Q9HAU5|rcsb pdb:1UW4|rcsb pdb:2WJV|rcsb pdb:4CEK|rcsb pdb:4CEM|dip:DIP-31148N|refseq:NP_056357.1|refseq:NP_542166.1|mint:MINT-6539910(identity) - - - figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:u7doCYezlcCUKq//xhk0TZ2TD009606 rogid:+hTMzl+IgYWyiDMSv5s4TeGt3D89606 intact-crc:909ED391B2F4C679|rigid:d981YqRAiQhTjWWUJmEb9oL5/zE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96Q15 uniprotkb:Q92900 intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7801538|mint:MINT-6539908|imex:IM-11555-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)|mint:MINT-6539927(identity) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N|mint:MINT-6539912(identity) - - - figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:u7doCYezlcCUKq//xhk0TZ2TD009606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:909ED391B2F4C679|rigid:d981YqRAiQhTjWWUJmEb9oL5/zE false - flag tag:?-?(MINT-6539915) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96Q15 uniprotkb:Q9H1J1 intact:EBI-1049832|uniprotkb:O43305|uniprotkb:Q13284|uniprotkb:Q8NFX2|uniprotkb:Q96QV0|uniprotkb:Q96RW3|ensembl:ENSP00000402515 intact:EBI-521530|uniprotkb:Q5T8C3|uniprotkb:Q5T8C9|uniprotkb:Q7Z6N3|uniprotkb:Q86YK1|uniprotkb:Q9BZI8|uniprotkb:A2A366|ensembl:ENSP00000364448 psi-mi:smg1_human(display_long)|uniprotkb:Lambda/iota protein kinase C-interacting protein(gene name synonym)|uniprotkb:61E3.4(gene name synonym)|uniprotkb:SMG1(gene name)|psi-mi:SMG1(display_short)|uniprotkb:ATX(gene name synonym)|uniprotkb:KIAA0421(gene name synonym)|uniprotkb:LIP(gene name synonym) psi-mi:ren3a_human(display_long)|uniprotkb:Nonsense mRNA reducing factor 3A(gene name synonym)|uniprotkb:Up-frameshift suppressor 3 homolog A(gene name synonym)|uniprotkb:UPF3A(gene name)|psi-mi:UPF3A(display_short)|uniprotkb:RENT3A(gene name synonym)|uniprotkb:UPF3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ivanov et al. (2008) pubmed:18256688|imex:IM-11555|mint:MINT-6539744 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7801538|mint:MINT-6539908|imex:IM-11555-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055907.3|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR031559|interpro:IPR035175|interpro:IPR036940|interpro:IPR039414|mint:Q96Q15|rcsb pdb:6L53|rcsb pdb:6L54|rcsb pdb:6SYT|rcsb pdb:6Z3R|reactome:R-HSA-975957|ensembl:ENSG00000157106(gene)|ensembl:ENST00000446231(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032204"(regulation of telomere maintenance)|mint:MINT-6539927(identity) refseq:NP_075387.1|refseq:NP_542418.1|dip:DIP-31146N|ensembl:ENSG00000169062(gene)|ensembl:ENST00000375299(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051028"(mRNA transport)|interpro:IPR005120(Nonsense-mediated decay UPF3)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034978|interpro:IPR035979|interpro:IPR039722|mint:Q9H1J1|rcsb pdb:2L08|reactome:R-HSA-9010553|reactome:R-HSA-975957|mint:MINT-6539924(identity) - - - figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/05/05 2014/10/16 rogid:u7doCYezlcCUKq//xhk0TZ2TD009606 rogid:ZshZwJWB3XaNjEP/FJtQpcD99Ws9606 intact-crc:909ED391B2F4C679|rigid:d981YqRAiQhTjWWUJmEb9oL5/zE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)