#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18847 uniprotkb:P18847 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640185|imex:IM-19428-1 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001030287; PREY gene NM_001030287|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 intact-crc:EF05DCED8B423B6D|rigid:6FNwse4EY8weysJgFRNHcVTRbjE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:P18847 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640191|imex:IM-19428-2 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001030287; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 intact-crc:32BA045835D471C7|rigid:SODyyyOzoUkGtdRDKjxPqlf11OU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:P18847 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640197|imex:IM-19428-3 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001030287; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 intact-crc:1A8BC6CC7DE843CE|rigid:LLwBE4raGYAXcnrJYXqP+fsq2Gc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18848 uniprotkb:Q9UDV6 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640218|imex:IM-19428-4 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001675; PREY gene NM_012256|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:6E4C530557DF874F|rigid:NrGI1ujmOSFm18P/OarDvpp6BZE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:O75175 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640224|imex:IM-19428-5 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_014516; PREY gene NM_002167|comment:The ORF of CNOT3 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 intact-crc:7EE1812B47ED6B35|rigid:4xP6b994mmn6UQ1OXzfkAZvL8F0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41240 uniprotkb:Q02535 intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640233|imex:IM-19428-6 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_004383; PREY gene NM_002167|comment:The ORF of CSK used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:9615F8528B37203B|rigid:+JLBv3UAQr6XlVYXtyg8Vgm1roE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q92785 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640292|imex:IM-19428-7 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_006268; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 intact-crc:3C66194A40460B95|rigid:g/GF41q1fHC/OlptUy026l1SvB0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18847 uniprotkb:Q14192 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640298|imex:IM-19428-8 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_001030287|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:7F91EAC04CB30DE5|rigid:SODyyyOzoUkGtdRDKjxPqlf11OU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41240 uniprotkb:Q14192 intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640308|imex:IM-19428-9 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_004383|comment:The ORF of CSK used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:16E42F940D732E0F|rigid:10Pz+Qmu9yPEQ6OdecZEDYkgyc0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q92785 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640323|imex:IM-19428-10 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_006268|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 intact-crc:9097FBEF9EE7A0A3|rigid:g/GF41q1fHC/OlptUy026l1SvB0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHR5 uniprotkb:Q14192 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640336|imex:IM-19428-11 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_013260|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:6DB557A306F2F3C3|rigid:LRQO9910C1DquVvRixnp6mIS/0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q02535 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640351|imex:IM-19428-12 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:560F0B015CBE5B2A|rigid:FPhqmLL7C9ARyaaoOHdLGhhJyCQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHX1 uniprotkb:Q14192 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640358|imex:IM-19428-13 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_014281|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:768ACB2BF307D0D6|rigid:jVo47p0ZSNJOq3ifSpwv5JOk/9g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:P40763 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640366|imex:IM-19428-14 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N - - crc64:6C00632211C8012D figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_003150|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 intact-crc:AD1EFB4A9418E3BC|rigid:NuoAKdF3BCnm44LOtJSQreWxKQY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQX6 uniprotkb:Q14192 intact:EBI-1640372|uniprotkb:Q96GJ4|ensembl:ENSP00000253144|ensembl:ENSP00000393817|ensembl:ENSP00000421014|ensembl:ENSP00000421728|ensembl:ENSP00000423156|ensembl:ENSP00000425517|ensembl:ENSP00000427439|ensembl:ENSP00000496977|ensembl:ENSP00000497263|ensembl:ENSP00000497652|ensembl:ENSP00000497726|ensembl:ENSP00000498006 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:zn331_human(display_long)|uniprotkb:ZNF331(gene name)|psi-mi:ZNF331(display_short)|uniprotkb:RITA(gene name synonym)|uniprotkb:ZNF463(gene name synonym)|uniprotkb:ZNF361(gene name synonym)|uniprotkb:Zinc finger protein 361(gene name synonym)|uniprotkb:Zinc finger protein 463(gene name synonym)|uniprotkb:C2H2-like zinc finger protein rearranged in thyroid adenomas(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640387|imex:IM-19428-15 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525378.1|refseq:XP_011525380.1|refseq:NP_001073375.1|refseq:NP_001073376.1|refseq:NP_061025.5|refseq:NP_001304042.1|refseq:NP_001304043.1|refseq:NP_001304044.1|refseq:NP_001304045.1|refseq:NP_001304046.1|refseq:NP_001304047.1|refseq:NP_001304048.1|refseq:NP_001304049.1|refseq:NP_001304050.1|refseq:XP_016882425.1|refseq:XP_016882426.1|refseq:XP_016882427.1|refseq:XP_016882428.1|refseq:XP_016882429.1|refseq:NP_001240727.1|refseq:NP_001240728.1|refseq:NP_001240729.1|refseq:NP_001240730.1|ensembl:ENSG00000130844(gene)|ensembl:ENST00000253144(transcript)|ensembl:ENST00000449416(transcript)|ensembl:ENST00000504493(transcript)|ensembl:ENST00000511154(transcript)|ensembl:ENST00000511593(transcript)|ensembl:ENST00000512387(transcript)|ensembl:ENST00000513999(transcript)|ensembl:ENST00000648122(transcript)|ensembl:ENST00000648236(transcript)|ensembl:ENST00000648397(transcript)|ensembl:ENST00000648511(transcript)|ensembl:ENST00000649326(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_018555|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:12iKnN4721K6MdVc3fNps/dbruk9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:53EC62B0E0CEE897|rigid:KZcyzvTuabiaLRIAJUpQ/B6hq/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q9H9D4 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640393|imex:IM-19428-16 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_024741|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:61AA1634940E52A0|rigid:o/mS6KeCnxWwYHRMP9nwS0g1sns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68DY1 uniprotkb:Q14192 intact:EBI-1640399|uniprotkb:Q8N8T4|uniprotkb:Q96QM1|ensembl:ENSP00000469958 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:zn626_human(display_long)|uniprotkb:ZNF626(gene name)|psi-mi:ZNF626(display_short) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640417|imex:IM-19428-17 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070143.1|refseq:NP_660340.1|ensembl:ENSG00000188171(gene)|ensembl:ENST00000601440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_145297|comment:The ORF of ZNF626 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:tF3sX34c5wSVHW6nCDA2edNG6hg9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:CE2F901A5F5E836F|rigid:qLSgYugzZcV9TC8XMyuPrup9NGA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H2S9 uniprotkb:Q14192 intact:EBI-1640423|uniprotkb:Q96JP3|ensembl:ENSP00000262032|ensembl:ENSP00000412101|ensembl:ENSP00000448419 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:ikzf4_human(display_long)|uniprotkb:IKZF4(gene name)|psi-mi:IKZF4(display_short)|uniprotkb:KIAA1782(gene name synonym)|uniprotkb:ZNFN1A4(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 4(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640444|imex:IM-19428-18 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071910.3|refseq:XP_016875294.1|refseq:XP_016875295.1|refseq:XP_016875296.1|refseq:XP_016875297.1|refseq:XP_016875298.1|refseq:XP_016875299.1|refseq:XP_016875300.1|ensembl:ENSG00000123411(gene)|ensembl:ENST00000262032(transcript)|ensembl:ENST00000431367(transcript)|ensembl:ENST00000547167(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MA7 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_022465|comment:The ORF of ZNFN1A4 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Y/VhY1coCpX0QIMQ7xJ//L2CvIo9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:F136F1FE0E269051|rigid:wgFDCmIka+BulHkIKeqp0R0AZyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6FHM2 uniprotkb:Q02535 intact:EBI-1640450 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:q6fhm2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:hCG_20449(orf name) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640459|imex:IM-19428-19 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005264.2|dip:DIP-600N|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_005273; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:1B4C4B2135530638|rigid:uEh0BJsjr0aV/XDbr8eOJs8XgRQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36915 uniprotkb:P31150 intact:EBI-1640465|uniprotkb:Q96CT5|uniprotkb:B0S838|intact:EBI-28985769|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000394290|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000409367|ensembl:ENSP00000411162 intact:EBI-946999|uniprotkb:P50394|uniprotkb:Q7Z2G6|uniprotkb:Q7Z2G9|uniprotkb:Q7Z2H5|uniprotkb:Q7Z2I6|uniprotkb:Q6FG50|ensembl:ENSP00000394071 psi-mi:gnl1_human(display_long)|uniprotkb:GNL1(gene name)|psi-mi:GNL1(display_short)|uniprotkb:HSR1(gene name synonym)|uniprotkb:GTP-binding protein HSR1(gene name synonym) psi-mi:gdia_human(display_long)|uniprotkb:GDI1(gene name)|psi-mi:GDI1(display_short)|uniprotkb:OPHN2(gene name synonym)|uniprotkb:RABGDIA(gene name synonym)|uniprotkb:XAP4(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)|uniprotkb:Oligophrenin-2(gene name synonym)|uniprotkb:Protein XAP-4(gene name synonym)|uniprotkb:GDIL(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640486|imex:IM-19428-20 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005266.2|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000411162|refseq:XP_005249072.1|ensembl:ENSP00000409367|ensembl:ENSP00000394290|ensembl:ENSG00000204590(gene)|ensembl:ENSG00000206492(gene)|ensembl:ENSG00000226882(gene)|ensembl:ENSG00000228581(gene)|ensembl:ENSG00000229470(gene)|ensembl:ENSG00000232143(gene)|ensembl:ENSG00000235986(gene)|ensembl:ENST00000376621(transcript)|ensembl:ENST00000383596(transcript)|ensembl:ENST00000417834(transcript)|ensembl:ENST00000428189(transcript)|ensembl:ENST00000437917(transcript)|ensembl:ENST00000441604(transcript)|ensembl:ENST00000454829(transcript)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358 refseq:NP_001484.1|ensembl:ENSG00000203879(gene)|ensembl:ENST00000447750(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P31150|reactome:R-HSA-8876198 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_005275; PREY gene NM_001493|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Drue+vqGnBPWoJpkTE5SwD93fbs9606 rogid:bE8RgEdzf7V/T+hWdGJkM9WM0yI9606 intact-crc:CE8982ECA3B60DCD|rigid:q9S2uTTp5hAKhbXI4rfwoKFhsTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36915 uniprotkb:Q93096 intact:EBI-1640465|uniprotkb:Q96CT5|uniprotkb:B0S838|intact:EBI-28985769|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000394290|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000409367|ensembl:ENSP00000411162 intact:EBI-1058467|uniprotkb:O00648|uniprotkb:Q49A54|uniprotkb:B2R6C8|intact:EBI-1640492|ensembl:ENSP00000485687|ensembl:ENSP00000497588|ensembl:ENSP00000500859|ensembl:ENSP00000500952 psi-mi:gnl1_human(display_long)|uniprotkb:GNL1(gene name)|psi-mi:GNL1(display_short)|uniprotkb:HSR1(gene name synonym)|uniprotkb:GTP-binding protein HSR1(gene name synonym) psi-mi:tp4a1_human(display_long)|uniprotkb:PTP4A1(gene name)|psi-mi:PTP4A1(display_short)|uniprotkb:PRL1(gene name synonym)|uniprotkb:PTPCAAX1(gene name synonym)|uniprotkb:"PTP(CAAXI)"(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640506|imex:IM-19428-21 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005266.2|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000411162|refseq:XP_005249072.1|ensembl:ENSP00000409367|ensembl:ENSP00000394290|ensembl:ENSG00000204590(gene)|ensembl:ENSG00000206492(gene)|ensembl:ENSG00000226882(gene)|ensembl:ENSG00000228581(gene)|ensembl:ENSG00000229470(gene)|ensembl:ENSG00000232143(gene)|ensembl:ENSG00000235986(gene)|ensembl:ENST00000376621(transcript)|ensembl:ENST00000383596(transcript)|ensembl:ENST00000417834(transcript)|ensembl:ENST00000428189(transcript)|ensembl:ENST00000437917(transcript)|ensembl:ENST00000441604(transcript)|ensembl:ENST00000454829(transcript)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358 refseq:NP_003454.1|ensembl:ENSG00000112245(gene)|ensembl:ENST00000626021(transcript)|ensembl:ENST00000648894(transcript)|ensembl:ENST00000672924(transcript)|ensembl:ENST00000673199(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0007049"(cell cycle)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|rcsb pdb:1RXD|rcsb pdb:1XM2|rcsb pdb:5BX1|refseq:XP_016866759.1|refseq:XP_016866760.1|refseq:XP_011534413.1|refseq:XP_011534414.1 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_005275; PREY gene NM_003463|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Drue+vqGnBPWoJpkTE5SwD93fbs9606 rogid:Eza5NsYNd+5ml6QEEmkQv5pAZ789606 intact-crc:50B6DC30BAE86344|rigid:DemgKP6pGjBQSjSXRKrirQZB+Hs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHR5 uniprotkb:Q9UHX1 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640512|imex:IM-19428-22 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_013260; PREY gene NM_014281|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 intact-crc:61425625FE29FF19|rigid:3KEqUve8URO4XIAne3DOL2ahj9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q14192 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640518|imex:IM-19428-23 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_001450; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:95553A8EB59E29B8|rigid:cbScIT3zUWkGI67kHM7fnKWo70c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:Q02535 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640531|imex:IM-19428-24 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_002167; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:F389BA94A0C256E9|rigid:eEHg3OeKNJrzVm+Z38lV+QyqQXo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25963 uniprotkb:P18848 intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym) psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640592|imex:IM-19428-25 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N - - crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_020529; PREY gene NM_001675|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 intact-crc:E5D98BFD331E0476|rigid:TBZ2z5yGCQTZ8W15YXdIFBN98/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBX8 uniprotkb:Q8TBX8 intact:EBI-1383637|ensembl:ENSP00000347032|ensembl:ENSP00000439878|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44 intact:EBI-1383637|ensembl:ENSP00000347032|ensembl:ENSP00000439878|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44 psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym) psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640610|imex:IM-19428-26 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript)|ensembl:ENST00000540759(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043229"(intracellular organelle)|refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:Q8TBX8|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|rcsb pdb:2GK9|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript)|ensembl:ENST00000540759(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043229"(intracellular organelle)|refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:Q8TBX8|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|rcsb pdb:2GK9|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_024779; PREY gene NM_024779|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 intact-crc:540BF54BBA318599|rigid:Vid85i151i0+nzqOuRRpsqX6giI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70SY1 uniprotkb:Q93096 intact:EBI-1640632|uniprotkb:Q6P454|uniprotkb:Q6ZMR6|ensembl:ENSP00000329140 intact:EBI-1058467|uniprotkb:O00648|uniprotkb:Q49A54|uniprotkb:B2R6C8|intact:EBI-1640492|ensembl:ENSP00000485687|ensembl:ENSP00000497588|ensembl:ENSP00000500859|ensembl:ENSP00000500952 psi-mi:cr3l2_human(display_long)|uniprotkb:CREB3L2(gene name)|psi-mi:CREB3L2(display_short)|uniprotkb:BBF2H7(gene name synonym)|uniprotkb:BBF2 human homolog on chromosome 7(gene name synonym) psi-mi:tp4a1_human(display_long)|uniprotkb:PTP4A1(gene name)|psi-mi:PTP4A1(display_short)|uniprotkb:PRL1(gene name synonym)|uniprotkb:PTPCAAX1(gene name synonym)|uniprotkb:"PTP(CAAXI)"(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640659|imex:IM-19428-27 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_919047.2|refseq:NP_001240704.1|ensembl:ENSG00000182158(gene)|ensembl:ENST00000330387(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051216"(cartilage development)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029804|reactome:R-HSA-8874211 refseq:NP_003454.1|ensembl:ENSG00000112245(gene)|ensembl:ENST00000626021(transcript)|ensembl:ENST00000648894(transcript)|ensembl:ENST00000672924(transcript)|ensembl:ENST00000673199(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0007049"(cell cycle)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|rcsb pdb:1RXD|rcsb pdb:1XM2|rcsb pdb:5BX1|refseq:XP_016866759.1|refseq:XP_016866760.1|refseq:XP_011534413.1|refseq:XP_011534414.1 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_003463; PREY gene NM_194071|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:7ShdjPSg0OzpWR5cof228Ebx+lI9606 rogid:Eza5NsYNd+5ml6QEEmkQv5pAZ789606 intact-crc:97D66EE56331914B|rigid:7Rk6ssyakrZ8hQ3gPksxt0OS2QU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q99623 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640675|imex:IM-19428-28 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_007273; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 intact-crc:A068632F87632FEB|rigid:9cya5OM+GxiFHGFcERayIXRjVTk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92730 uniprotkb:Q70SY1 intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461 intact:EBI-1640632|uniprotkb:Q6P454|uniprotkb:Q6ZMR6|ensembl:ENSP00000329140 psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym) psi-mi:cr3l2_human(display_long)|uniprotkb:CREB3L2(gene name)|psi-mi:CREB3L2(display_short)|uniprotkb:BBF2H7(gene name synonym)|uniprotkb:BBF2 human homolog on chromosome 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640683|imex:IM-19428-29 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273 refseq:NP_919047.2|refseq:NP_001240704.1|ensembl:ENSG00000182158(gene)|ensembl:ENST00000330387(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051216"(cartilage development)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029804|reactome:R-HSA-8874211 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_014470; PREY gene NM_194071|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606 rogid:7ShdjPSg0OzpWR5cof228Ebx+lI9606 intact-crc:96D849BD8B1D00E0|rigid:XgWzT5E5NtN6NZD2AkGuA2JHTvk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:Q92730 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640689|imex:IM-19428-30 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_014470; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606 intact-crc:96372DA1CC83501A|rigid:0KXqs99mh6dN7c3rl/gqHDtwDU8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHX1 uniprotkb:Q9UHR5 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640701|imex:IM-19428-31 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_014281; PREY gene NM_013260|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 intact-crc:D983B7C9E25673E6|rigid:3KEqUve8URO4XIAne3DOL2ahj9E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:Q9UHX1 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640826|imex:IM-19428-32 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_014281; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 intact-crc:AD9D0CD2BA198EE8|rigid:Q7E2KKL5CEAUSdIjSHI0GoAVIsk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHR5 uniprotkb:Q9UH92 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73 psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640839|imex:IM-19428-33 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_198205; PREY gene NM_013260|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606 intact-crc:7BE14B36845B8C9E|rigid:VxCoKuxlpjEePpAEsVSS9mGwbec false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UH92 uniprotkb:Q02535 intact:EBI-741109|intact:EBI-28976799|ensembl:ENSP00000246912|uniprotkb:Q53XM6|uniprotkb:Q96FL2|uniprotkb:Q9H2V0|uniprotkb:Q9H2V1|uniprotkb:Q9H2V2|uniprotkb:Q9NXN3|uniprotkb:B2RAV8|uniprotkb:A8K2J3|uniprotkb:B2RD73 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:mlx_human(display_long)|uniprotkb:Max-like bHLHZip protein(gene name synonym)|uniprotkb:BHLHD13(gene name synonym)|uniprotkb:Protein BigMax(gene name synonym)|uniprotkb:Transcription factor-like protein 4(gene name synonym)|uniprotkb:MLX(gene name)|psi-mi:MLX(display_short)|uniprotkb:TCFL4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 13(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640845|imex:IM-19428-34 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_733752.1|refseq:NP_937847.1|refseq:NP_937848.1|ensembl:ENSG00000108788(gene)|ensembl:ENST00000246912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032647|interpro:IPR036638|reactome:R-HSA-163765|go:"GO:0005654"(nucleoplasm)|ensembl:ENSP00000246912|ensembl:ENST00000346833|ensembl:ENSP00000320913|ensembl:ENST00000435881|ensembl:ENSP00000416627 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_198205; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:5zIr/dC+5Gre7BiEy/8g0MEdppY9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:A11D18746C05B9E1|rigid:F3oCb2uT1HgsQK5UctXXCcsaSgk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:P18847 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640851|imex:IM-19428-35 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_001030287|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 intact-crc:1694C6D34B1C3015|rigid:I6DZ6vlE18jzVKCBTTyIw1b5oHI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q70SY1 uniprotkb:Q9UDV6 intact:EBI-1640632|uniprotkb:Q6P454|uniprotkb:Q6ZMR6|ensembl:ENSP00000329140 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:cr3l2_human(display_long)|uniprotkb:CREB3L2(gene name)|psi-mi:CREB3L2(display_short)|uniprotkb:BBF2H7(gene name synonym)|uniprotkb:BBF2 human homolog on chromosome 7(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640859|imex:IM-19428-36 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_919047.2|refseq:NP_001240704.1|ensembl:ENSG00000182158(gene)|ensembl:ENST00000330387(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051216"(cartilage development)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029804|reactome:R-HSA-8874211 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_194071|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:7ShdjPSg0OzpWR5cof228Ebx+lI9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:97831C776E052A1A|rigid:7K7ifPMJ3Kz2SJ94zeg1zP9lQN0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41240 uniprotkb:Q9UDV6 intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640871|imex:IM-19428-37 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_004383|comment:The ORFs of ZNF212 and CSK used in this study encoded truncated protein products missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:7B43874819D21331|rigid:9HFQzaZUcZf/bDP8eXqopRJOlDY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92785 uniprotkb:Q9UDV6 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640878|imex:IM-19428-38 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_006268|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:F0A42CD37A63281B|rigid:Hw7krU2Cpy1OPp7oQUFM2CvES7o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16828 uniprotkb:Q9UDV6 intact:EBI-746870|uniprotkb:O75109|uniprotkb:Q53Y75|uniprotkb:Q9BSH6|ensembl:ENSP00000279488 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:dus6_human(display_long)|uniprotkb:Mitogen-activated protein kinase phosphatase 3(gene name synonym)|uniprotkb:Dual specificity protein phosphatase PYST1(gene name synonym)|uniprotkb:DUSP6(gene name)|psi-mi:DUSP6(display_short)|uniprotkb:MKP3(gene name synonym)|uniprotkb:PYST1(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640884|imex:IM-19428-39 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001937.2|refseq:NP_073143.2|ensembl:ENSG00000139318(gene)|ensembl:ENST00000279488(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008330"(protein tyrosine/threonine phosphatase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0017017"(MAP kinase tyrosine/serine/threonine phosphatase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR008343(MAP kinase phosphatase)|interpro:IPR020422|interpro:IPR029021|interpro:IPR036873|mint:Q16828|rcsb pdb:1HZM|rcsb pdb:1MKP|reactome:R-HSA-112409|reactome:R-HSA-202670|reactome:R-HSA-5675221|reactome:R-HSA-9652817 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_001946|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:UQP1V1ZGM5snVav5HzVFnLA360o9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:93237C5A88278E7E|rigid:l2Ao/SGL2hDp5X2HyBVPtSwoyWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q9UDV6 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640890|imex:IM-19428-40 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_001450|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:F3C3206AF8C9204E|rigid:a+862TM5vmgThoRHK+0yvt8SoRU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:P36915 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640465|uniprotkb:Q96CT5|uniprotkb:B0S838|intact:EBI-28985769|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000394290|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000409367|ensembl:ENSP00000411162 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:gnl1_human(display_long)|uniprotkb:GNL1(gene name)|psi-mi:GNL1(display_short)|uniprotkb:HSR1(gene name synonym)|uniprotkb:GTP-binding protein HSR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640899|imex:IM-19428-41 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_005266.2|ensembl:ENSP00000365806|ensembl:ENSP00000373090|ensembl:ENSP00000403576|ensembl:ENSP00000409074|ensembl:ENSP00000411162|refseq:XP_005249072.1|ensembl:ENSP00000409367|ensembl:ENSP00000394290|ensembl:ENSG00000204590(gene)|ensembl:ENSG00000206492(gene)|ensembl:ENSG00000226882(gene)|ensembl:ENSG00000228581(gene)|ensembl:ENSG00000229470(gene)|ensembl:ENSG00000232143(gene)|ensembl:ENSG00000235986(gene)|ensembl:ENST00000376621(transcript)|ensembl:ENST00000383596(transcript)|ensembl:ENST00000417834(transcript)|ensembl:ENST00000428189(transcript)|ensembl:ENST00000437917(transcript)|ensembl:ENST00000441604(transcript)|ensembl:ENST00000454829(transcript)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_005275|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:Drue+vqGnBPWoJpkTE5SwD93fbs9606 intact-crc:A4E4369C72AADB87|rigid:cDF9gUQvVun6l9WNWLbkmbRXjiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60381 uniprotkb:Q9UDV6 intact:EBI-954175|ensembl:ENSP00000222574|ensembl:ENSP00000418738|ensembl:ENSP00000420500|ensembl:ENSP00000491311|ensembl:ENSP00000492167|ensembl:ENSP00000492343|uniprotkb:Q8TBM1|uniprotkb:Q8TE93|uniprotkb:Q96AJ2|uniprotkb:B3KVB7 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:hbp1_human(display_long)|uniprotkb:HMG box transcription factor 1(gene name synonym)|uniprotkb:High mobility group box transcription factor 1(gene name synonym)|uniprotkb:HBP1(gene name)|psi-mi:HBP1(display_short) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640911|imex:IM-19428-42 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000105856(gene)|ensembl:ENSG00000283847(gene)|ensembl:ENST00000222574(transcript)|ensembl:ENST00000468410(transcript)|ensembl:ENST00000485846(transcript)|ensembl:ENST00000638303(transcript)|ensembl:ENST00000638893(transcript)|ensembl:ENST00000640195(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036096|interpro:IPR036910|interpro:IPR039655|rcsb pdb:2E6O|rcsb pdb:3QVE|refseq:NP_036389.2|refseq:NP_001231191.1|refseq:XP_005250323.1|refseq:XP_005250324.1|refseq:XP_016867456.1 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_012257|comment:The ORFs of HBP1 and ZNF212 used in this study encoded truncated protein products missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:w0Y0uk7CSIHtVWindV1UDg04WBA9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:E0AB56F601693BAC|rigid:EAZiRn5V74HMfDQMshX7/RAHapM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHR5 uniprotkb:Q9UDV6 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640917|imex:IM-19428-43 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_013260|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:10A01A587711F854|rigid:BPqlZntx+71WlNBixUgbVlXbwnY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:P25963 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640923|imex:IM-19428-44 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_020529|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606 intact-crc:EC5301C01B2DB031|rigid:xN+dvVVcZW8P5wbeNMoJyJrCbj4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q93096 uniprotkb:Q9UDV6 intact:EBI-1058467|uniprotkb:O00648|uniprotkb:Q49A54|uniprotkb:B2R6C8|intact:EBI-1640492|ensembl:ENSP00000485687|ensembl:ENSP00000497588|ensembl:ENSP00000500859|ensembl:ENSP00000500952 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:tp4a1_human(display_long)|uniprotkb:PTP4A1(gene name)|psi-mi:PTP4A1(display_short)|uniprotkb:PRL1(gene name synonym)|uniprotkb:PTPCAAX1(gene name synonym)|uniprotkb:"PTP(CAAXI)"(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 4a1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase of regenerating liver 1(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640940|imex:IM-19428-45 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003454.1|ensembl:ENSG00000112245(gene)|ensembl:ENST00000626021(transcript)|ensembl:ENST00000648894(transcript)|ensembl:ENST00000672924(transcript)|ensembl:ENST00000673199(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0007049"(cell cycle)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR020422|interpro:IPR029021|rcsb pdb:1RXD|rcsb pdb:1XM2|rcsb pdb:5BX1|refseq:XP_016866759.1|refseq:XP_016866760.1|refseq:XP_011534413.1|refseq:XP_011534414.1 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_003463|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Eza5NsYNd+5ml6QEEmkQv5pAZ789606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:7C34B610DBD1BF20|rigid:dlgFNb6WCtiYxJxj/xIW8NTd1ZU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:Q8TAU0 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640929|uniprotkb:Q9NYS6|uniprotkb:B4DUZ4|ensembl:ENSP00000342828 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:nkx23_human(display_long)|uniprotkb:NKX2-3(gene name)|psi-mi:NKX2-3(display_short)|uniprotkb:NKX23(gene name synonym)|uniprotkb:NKX2C(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640947|imex:IM-19428-46 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_660328.2|ensembl:ENSG00000119919(gene)|ensembl:ENST00000344586(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043367"(CD4-positive, alpha-beta T cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048621"(post-embryonic digestive tract morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_145285|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:GfdcZ5et9FuSHHNuZzPzxMc4zbk9606 intact-crc:A03B2F6FFD1D4319|rigid:XIxfaWcFpjGFg8WPEH7RBmV69kI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92730 uniprotkb:Q9UDV6 intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640953|imex:IM-19428-47 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_014470|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:B8844CACB595A90E|rigid:0GfEU+SjYJEQ0JJD8ac7xDg0xao false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:Q9UDV6 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640959|imex:IM-19428-48 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_012256|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:2525FE49EE28FB21|rigid:ttb55+9dOo8LflIQ+4+xatYPlLc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:P17036 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640985|imex:IM-19428-49 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_032924|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:B8241AEC7B025501|rigid:zTa3FfOEigHZwgzxKWTDq1EHO5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQX6 uniprotkb:Q9UDV6 intact:EBI-1640372|uniprotkb:Q96GJ4|ensembl:ENSP00000253144|ensembl:ENSP00000393817|ensembl:ENSP00000421014|ensembl:ENSP00000421728|ensembl:ENSP00000423156|ensembl:ENSP00000425517|ensembl:ENSP00000427439|ensembl:ENSP00000496977|ensembl:ENSP00000497263|ensembl:ENSP00000497652|ensembl:ENSP00000497726|ensembl:ENSP00000498006 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:zn331_human(display_long)|uniprotkb:ZNF331(gene name)|psi-mi:ZNF331(display_short)|uniprotkb:RITA(gene name synonym)|uniprotkb:ZNF463(gene name synonym)|uniprotkb:ZNF361(gene name synonym)|uniprotkb:Zinc finger protein 361(gene name synonym)|uniprotkb:Zinc finger protein 463(gene name synonym)|uniprotkb:C2H2-like zinc finger protein rearranged in thyroid adenomas(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640992|imex:IM-19428-50 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525378.1|refseq:XP_011525380.1|refseq:NP_001073375.1|refseq:NP_001073376.1|refseq:NP_061025.5|refseq:NP_001304042.1|refseq:NP_001304043.1|refseq:NP_001304044.1|refseq:NP_001304045.1|refseq:NP_001304046.1|refseq:NP_001304047.1|refseq:NP_001304048.1|refseq:NP_001304049.1|refseq:NP_001304050.1|refseq:XP_016882425.1|refseq:XP_016882426.1|refseq:XP_016882427.1|refseq:XP_016882428.1|refseq:XP_016882429.1|refseq:NP_001240727.1|refseq:NP_001240728.1|refseq:NP_001240729.1|refseq:NP_001240730.1|ensembl:ENSG00000130844(gene)|ensembl:ENST00000253144(transcript)|ensembl:ENST00000449416(transcript)|ensembl:ENST00000504493(transcript)|ensembl:ENST00000511154(transcript)|ensembl:ENST00000511593(transcript)|ensembl:ENST00000512387(transcript)|ensembl:ENST00000513999(transcript)|ensembl:ENST00000648122(transcript)|ensembl:ENST00000648236(transcript)|ensembl:ENST00000648397(transcript)|ensembl:ENST00000648511(transcript)|ensembl:ENST00000649326(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_018555|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:12iKnN4721K6MdVc3fNps/dbruk9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:293FA77D9DE1C732|rigid:vMiwCGw2DFXHtEyOOu5sO126WEc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:Q9H9D4 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1640998|imex:IM-19428-51 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_012256; PREY gene NM_024741|comment:The ORFs of ZNF408 and ZNF212 used in this study encoded truncated protein products missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:E0BADE8B5A44FDCE|rigid:mOb7OUv6NB0RBSBYF3Rm21AQ4io false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17036 uniprotkb:Q14192 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641012|imex:IM-19428-52 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_032924; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:ED3C95ECA72E36B4|rigid:GvNifQ581QmT30dgvOHS9iZry7A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:P17036 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641027|imex:IM-19428-53 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_032924; PREY gene NM_002167|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:791F60D70CF22239|rigid:/yv5rp3lwj3G8SylpuG9KqdWE7M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UDV6 uniprotkb:P17036 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641033|imex:IM-19428-54 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_032924; PREY gene NM_012256|comment:The ORF of ZNF212 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:226E49577E15C035|rigid:zTa3FfOEigHZwgzxKWTDq1EHO5k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17036 uniprotkb:P17036 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641039|imex:IM-19428-55 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_032924; PREY gene NM_032924|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:559023B4847D9BD9|rigid:+w3Y3aXqa3chRya9bUUGpgXetTY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NQX6 uniprotkb:Q14192 intact:EBI-1640372|uniprotkb:Q96GJ4|ensembl:ENSP00000253144|ensembl:ENSP00000393817|ensembl:ENSP00000421014|ensembl:ENSP00000421728|ensembl:ENSP00000423156|ensembl:ENSP00000425517|ensembl:ENSP00000427439|ensembl:ENSP00000496977|ensembl:ENSP00000497263|ensembl:ENSP00000497652|ensembl:ENSP00000497726|ensembl:ENSP00000498006 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:zn331_human(display_long)|uniprotkb:ZNF331(gene name)|psi-mi:ZNF331(display_short)|uniprotkb:RITA(gene name synonym)|uniprotkb:ZNF463(gene name synonym)|uniprotkb:ZNF361(gene name synonym)|uniprotkb:Zinc finger protein 361(gene name synonym)|uniprotkb:Zinc finger protein 463(gene name synonym)|uniprotkb:C2H2-like zinc finger protein rearranged in thyroid adenomas(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641045|imex:IM-19428-56 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525378.1|refseq:XP_011525380.1|refseq:NP_001073375.1|refseq:NP_001073376.1|refseq:NP_061025.5|refseq:NP_001304042.1|refseq:NP_001304043.1|refseq:NP_001304044.1|refseq:NP_001304045.1|refseq:NP_001304046.1|refseq:NP_001304047.1|refseq:NP_001304048.1|refseq:NP_001304049.1|refseq:NP_001304050.1|refseq:XP_016882425.1|refseq:XP_016882426.1|refseq:XP_016882427.1|refseq:XP_016882428.1|refseq:XP_016882429.1|refseq:NP_001240727.1|refseq:NP_001240728.1|refseq:NP_001240729.1|refseq:NP_001240730.1|ensembl:ENSG00000130844(gene)|ensembl:ENST00000253144(transcript)|ensembl:ENST00000449416(transcript)|ensembl:ENST00000504493(transcript)|ensembl:ENST00000511154(transcript)|ensembl:ENST00000511593(transcript)|ensembl:ENST00000512387(transcript)|ensembl:ENST00000513999(transcript)|ensembl:ENST00000648122(transcript)|ensembl:ENST00000648236(transcript)|ensembl:ENST00000648397(transcript)|ensembl:ENST00000648511(transcript)|ensembl:ENST00000649326(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_018555; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:12iKnN4721K6MdVc3fNps/dbruk9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:39FE7E38DAA4861B|rigid:KZcyzvTuabiaLRIAJUpQ/B6hq/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:Q14192 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641051|imex:IM-19428-57 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_024741; PREY gene NM_001450|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:CB8A174E665D389A|rigid:o/mS6KeCnxWwYHRMP9nwS0g1sns false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHR5 uniprotkb:Q9H9D4 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641057|imex:IM-19428-58 author score:I - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_024741; PREY gene NM_013260|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:1DEE92B01383E4A2|rigid:FIfQL8job9Me+ImvBSMqoil/mgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:Q9NQX6 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-1640372|uniprotkb:Q96GJ4|ensembl:ENSP00000253144|ensembl:ENSP00000393817|ensembl:ENSP00000421014|ensembl:ENSP00000421728|ensembl:ENSP00000423156|ensembl:ENSP00000425517|ensembl:ENSP00000427439|ensembl:ENSP00000496977|ensembl:ENSP00000497263|ensembl:ENSP00000497652|ensembl:ENSP00000497726|ensembl:ENSP00000498006 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:zn331_human(display_long)|uniprotkb:ZNF331(gene name)|psi-mi:ZNF331(display_short)|uniprotkb:RITA(gene name synonym)|uniprotkb:ZNF463(gene name synonym)|uniprotkb:ZNF361(gene name synonym)|uniprotkb:Zinc finger protein 361(gene name synonym)|uniprotkb:Zinc finger protein 463(gene name synonym)|uniprotkb:C2H2-like zinc finger protein rearranged in thyroid adenomas(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641066|imex:IM-19428-59 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:XP_011525378.1|refseq:XP_011525380.1|refseq:NP_001073375.1|refseq:NP_001073376.1|refseq:NP_061025.5|refseq:NP_001304042.1|refseq:NP_001304043.1|refseq:NP_001304044.1|refseq:NP_001304045.1|refseq:NP_001304046.1|refseq:NP_001304047.1|refseq:NP_001304048.1|refseq:NP_001304049.1|refseq:NP_001304050.1|refseq:XP_016882425.1|refseq:XP_016882426.1|refseq:XP_016882427.1|refseq:XP_016882428.1|refseq:XP_016882429.1|refseq:NP_001240727.1|refseq:NP_001240728.1|refseq:NP_001240729.1|refseq:NP_001240730.1|ensembl:ENSG00000130844(gene)|ensembl:ENST00000253144(transcript)|ensembl:ENST00000449416(transcript)|ensembl:ENST00000504493(transcript)|ensembl:ENST00000511154(transcript)|ensembl:ENST00000511593(transcript)|ensembl:ENST00000512387(transcript)|ensembl:ENST00000513999(transcript)|ensembl:ENST00000648122(transcript)|ensembl:ENST00000648236(transcript)|ensembl:ENST00000648397(transcript)|ensembl:ENST00000648511(transcript)|ensembl:ENST00000649326(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_018555; PREY gene NM_024741|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:12iKnN4721K6MdVc3fNps/dbruk9606 intact-crc:88312940F8DA02BC|rigid:ThiFzj4QaWcbRdzHQpb+KkHdwZo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:Q02535 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641072|imex:IM-19428-60 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_024741; PREY gene NM_002167|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 intact-crc:EFDD9B63E389A876|rigid:08pMOcgSfKQvdAzExf/DNAhVts0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9D4 uniprotkb:Q9H9D4 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641078|imex:IM-19428-61 author score:IV - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_024741; PREY gene NM_024741|comment:The ORF of ZNF408 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:6C762F6A0E720BB8|rigid:RaRuqwdAIMlvxmrA8vU68XRwZ1g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02535 uniprotkb:Q68DY1 intact:EBI-1387094|uniprotkb:O75641|uniprotkb:A8K1T8|ensembl:ENSP00000363689|ensembl:ENSP00000489102 intact:EBI-1640399|uniprotkb:Q8N8T4|uniprotkb:Q96QM1|ensembl:ENSP00000469958 psi-mi:id3_human(display_long)|uniprotkb:ID3(gene name)|psi-mi:ID3(display_short)|uniprotkb:1R21(gene name synonym)|uniprotkb:BHLHB25(gene name synonym)|uniprotkb:Inhibitor of DNA binding 3(gene name synonym)|uniprotkb:ID-like protein inhibitor HLH 1R21(gene name synonym)|uniprotkb:Helix-loop-helix protein HEIR-1(gene name synonym)|uniprotkb:HEIR1(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 25(gene name synonym)|uniprotkb:Inhibitor of differentiation 3(gene name synonym) psi-mi:zn626_human(display_long)|uniprotkb:ZNF626(gene name)|psi-mi:ZNF626(display_short) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641084|imex:IM-19428-62 author score:II - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002158.3|dip:DIP-713N|ensembl:ENSG00000117318(gene)|ensembl:ENSG00000283060(gene)|ensembl:ENST00000374561(transcript)|ensembl:ENST00000634790(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001656"(metanephros development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042476"(odontogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901707"(leptomycin B binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|rcsb pdb:2LFH|reactome:R-HSA-9031628 refseq:NP_001070143.1|refseq:NP_660340.1|ensembl:ENSG00000188171(gene)|ensembl:ENST00000601440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_145297; PREY gene NM_002167|comment:The ORF of ZNF626 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:EOy/Sn41BQc0qA/LeWAJGBxXqRI9606 rogid:tF3sX34c5wSVHW6nCDA2edNG6hg9606 intact-crc:6378AF04CFEA70AB|rigid:GdXdR5norax+j9P5ZwPBlkdXOlc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14192 uniprotkb:Q9H2S9 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-1640423|uniprotkb:Q96JP3|ensembl:ENSP00000262032|ensembl:ENSP00000412101|ensembl:ENSP00000448419 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:ikzf4_human(display_long)|uniprotkb:IKZF4(gene name)|psi-mi:IKZF4(display_short)|uniprotkb:KIAA1782(gene name synonym)|uniprotkb:ZNFN1A4(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641090|imex:IM-19428-63 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_071910.3|refseq:XP_016875294.1|refseq:XP_016875295.1|refseq:XP_016875296.1|refseq:XP_016875297.1|refseq:XP_016875298.1|refseq:XP_016875299.1|refseq:XP_016875300.1|ensembl:ENSG00000123411(gene)|ensembl:ENST00000262032(transcript)|ensembl:ENST00000431367(transcript)|ensembl:ENST00000547167(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MA7 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_022465; PREY gene NM_001450|comment:The ORF of ZNFN1A4 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:Y/VhY1coCpX0QIMQ7xJ//L2CvIo9606 intact-crc:26A1F252F5AA1CF6|rigid:wgFDCmIka+BulHkIKeqp0R0AZyo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25963 uniprotkb:Q9H2S9 intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6 intact:EBI-1640423|uniprotkb:Q96JP3|ensembl:ENSP00000262032|ensembl:ENSP00000412101|ensembl:ENSP00000448419 psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym) psi-mi:ikzf4_human(display_long)|uniprotkb:IKZF4(gene name)|psi-mi:IKZF4(display_short)|uniprotkb:KIAA1782(gene name synonym)|uniprotkb:ZNFN1A4(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641096|imex:IM-19428-64 author score:III - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N refseq:NP_071910.3|refseq:XP_016875294.1|refseq:XP_016875295.1|refseq:XP_016875296.1|refseq:XP_016875297.1|refseq:XP_016875298.1|refseq:XP_016875299.1|refseq:XP_016875300.1|ensembl:ENSG00000123411(gene)|ensembl:ENST00000262032(transcript)|ensembl:ENST00000431367(transcript)|ensembl:ENST00000547167(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MA7 - - - figure legend:Fig. 1, Table 1|author-identifiers:BAIT gene NM_022465; PREY gene NM_020529|comment:The ORF of ZNFN1A4 used in this study encoded a truncated protein product missing the C-terminal end.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/02/20 2014/10/16 rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606 rogid:Y/VhY1coCpX0QIMQ7xJ//L2CvIo9606 intact-crc:8A22302FEAA7B25D|rigid:YtkOFujIRfC83WofbuAGe6LZcDQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TBX8 uniprotkb:Q8TBX8 intact:EBI-1383637|ensembl:ENSP00000347032|ensembl:ENSP00000439878|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44 intact:EBI-1383637|ensembl:ENSP00000347032|ensembl:ENSP00000439878|uniprotkb:Q9H6N2|uniprotkb:B2RDL3|uniprotkb:B4DM11|uniprotkb:B4DY44 psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym) psi-mi:pi42c_human(display_long)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641110|imex:IM-19428-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript)|ensembl:ENST00000540759(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043229"(intracellular organelle)|refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:Q8TBX8|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|rcsb pdb:2GK9|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript)|ensembl:ENST00000540759(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043229"(intracellular organelle)|refseq:NP_001139730.1|refseq:NP_001139731.1|refseq:NP_079055.3|refseq:NP_001139732.1|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:Q8TBX8|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|rcsb pdb:2GK9|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_024779; PREY gene NM_024779|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 intact-crc:58B62252B0B6EAC9|rigid:Vid85i151i0+nzqOuRRpsqX6giI false glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P17036 uniprotkb:P17036 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641120|imex:IM-19428-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_032924; PREY gene NM_032924|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:232D00FDA8A3536D|rigid:+w3Y3aXqa3chRya9bUUGpgXetTY false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UDV6 uniprotkb:P17036 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641125|imex:IM-19428-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_032924; PREY gene NM_012256|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 intact-crc:1BC5AD30AB8294D0|rigid:zTa3FfOEigHZwgzxKWTDq1EHO5k false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P18847 uniprotkb:P18847 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641138|imex:IM-19428-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_001030287; PREY gene NM_001030287|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 intact-crc:2B567EC8EBAEA033|rigid:6FNwse4EY8weysJgFRNHcVTRbjE false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P17036 uniprotkb:Q9UDV6 intact:EBI-1640965|uniprotkb:P13683|uniprotkb:Q9NNX8|uniprotkb:Q9NXJ1|uniprotkb:Q9UC15|uniprotkb:Q9UC16|uniprotkb:Q9HBR4|uniprotkb:D6W5U0|ensembl:ENSP00000299667|ensembl:ENSP00000306372|ensembl:ENSP00000415358 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:znf3_human(display_long)|uniprotkb:ZNF3(gene name)|psi-mi:ZNF3(display_short)|uniprotkb:KOX25(gene name synonym)|uniprotkb:Zinc finger protein KOX25(gene name synonym)|uniprotkb:Zinc finger protein HF.12(gene name synonym)|uniprotkb:Zinc finger protein HZF3.1(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641143|imex:IM-19428-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265213.1|refseq:NP_001265216.1|refseq:NP_001265219.1|refseq:NP_060185.2|refseq:NP_116313.3|refseq:NP_001305064.1|refseq:NP_001305065.1|refseq:NP_001305066.1|ensembl:ENSG00000166526(gene)|ensembl:ENST00000299667(transcript)|ensembl:ENST00000303915(transcript)|ensembl:ENST00000424697(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_012256; PREY gene NM_032924|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:W0v1PZr++AseqeMmtx+sp4SOUYg9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:25AEC4DF0A765FD6|rigid:zTa3FfOEigHZwgzxKWTDq1EHO5k false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H9D4 uniprotkb:Q9H9D4 intact:EBI-347633|ensembl:ENSP00000309606 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641152|imex:IM-19428-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_024741; PREY gene NM_024741|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:F9361A060ABBC5AD|rigid:RaRuqwdAIMlvxmrA8vU68XRwZ1g false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UDV6 uniprotkb:Q9UDV6 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 intact:EBI-1640204|uniprotkb:Q13396|uniprotkb:Q8N664|uniprotkb:B2RCF4|ensembl:ENSP00000338572 psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:zn212_human(display_long)|uniprotkb:ZNF212(gene name)|psi-mi:ZNF212(display_short)|uniprotkb:ZNFC150(gene name synonym)|uniprotkb:Zinc finger protein C2H2-150(gene name synonym) psi-mi:"MI:0096"(pull down) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1641413|imex:IM-19428-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 refseq:NP_036388.2|ensembl:ENSG00000170260(gene)|ensembl:ENST00000335870(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|mint:Q9UDV6|reactome:R-HSA-212436 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_012256; PREY gene NM_012256|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/20 2014/10/16 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 rogid:jZtScr5t/MR83+d1tdA9OiP4JCA9606 intact-crc:F40533275B20D4A1|rigid:ttb55+9dOo8LflIQ+4+xatYPlLc false glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14192 uniprotkb:Q9H9D4 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-347633|ensembl:ENSP00000309606 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:zn408_human(display_long)|uniprotkb:ZNF408(gene name)|psi-mi:ZNF408(display_short)|uniprotkb:PFM14(gene name synonym)|uniprotkb:PRDM17(gene name synonym)|uniprotkb:PR domain zinc finger protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641434|imex:IM-19428-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 refseq:NP_001171680.1|refseq:NP_079017.1|ensembl:ENSG00000175213(gene)|ensembl:ENST00000311764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044412 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_001450; PREY gene NM_024741|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:VYheZbRzNxXoFvtRSwYv//yTtOU9606 intact-crc:54B51806C4509AC4|rigid:o/mS6KeCnxWwYHRMP9nwS0g1sns false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P18847 uniprotkb:Q14192 intact:EBI-712767|ensembl:ENSP00000344352|ensembl:ENSP00000355954|uniprotkb:Q5VTZ2|uniprotkb:Q6ICQ9|uniprotkb:Q7Z566|uniprotkb:Q8WYM6 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:atf3_human(display_long)|uniprotkb:Activating transcription factor 3(gene name synonym)|uniprotkb:ATF3(gene name)|psi-mi:ATF3(display_short) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641451|imex:IM-19428-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162772(gene)|ensembl:ENST00000341491(transcript)|ensembl:ENST00000366987(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061394"(regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:1903984"(positive regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029812|mint:P18847|reactome:R-HSA-380994|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_001025458.1|refseq:NP_001665.1|refseq:XP_011507881.1|refseq:NP_001035709.1|refseq:NP_001193413.2|refseq:NP_001193415.1|refseq:NP_001193417.2|refseq:XP_005273203.1|dip:DIP-344N ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_001450; PREY gene NM_001030287|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/20 2014/10/16 rogid:4OpideXaQoVFi+x4P6iN5PG6RKY9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:FAC78D906FF5366D|rigid:SODyyyOzoUkGtdRDKjxPqlf11OU false his tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14192 uniprotkb:Q14192 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641470|imex:IM-19428-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_001450; PREY gene NM_001450|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/20 2014/10/16 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 intact-crc:726D50DE8328D3B3|rigid:cbScIT3zUWkGI67kHM7fnKWo70c false his tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UHX1 uniprotkb:Q9UHR5 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gao et al. (2008) pubmed:18255255|imex:IM-19428 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1641480|imex:IM-19428-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - - - figure legend:Fig. 3|author-identifiers:BAIT gene NM_013260; PREY gene NM_014281|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/02/20 2014/10/16 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 intact-crc:BD72233331B67E50|rigid:3KEqUve8URO4XIAne3DOL2ahj9E false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)