#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03330 intact:EBI-1177816 intact:EBI-7458|uniprotkb:Q6B165|uniprotkb:D6VV32|ensemblfungi:YGR252W - psi-mi:gcn5_yeast(display_long)|uniprotkb:YGR252W(locus name)|uniprotkb:GCN5(gene name)|psi-mi:GCN5(display_short)|uniprotkb:ADA4(gene name synonym)|uniprotkb:SWI9(gene name synonym) psi-mi:h3_peptide-2-21(display_short)|psi-mi:EBI-1177816(display_long) psi-mi:"MI:0107"(surface plasmon resonance) Shimada et al. (2008) imex:IM-12025|pubmed:18243098 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1645604|imex:IM-12025-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_011768.1|sgd:S000003484|mint:Q03330|dip:DIP-710N|ensemblfungi:YGR252W(gene)|ensemblfungi:YGR252W_mRNA(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0140068"(histone crotonyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|rcsb pdb:1E6I|rcsb pdb:1YGH|rcsb pdb:6CW2|rcsb pdb:6CW3|reactome:R-SCE-5689880|reactome:R-SCE-9018519 uniprotkb:P84243(multiple parent)|uniprotkb:Q71DI3(multiple parent) go:"GO:0006468"(protein phosphorylation) crc64:3200730DDC7EF70D no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Contains consensus aminoacids 1-21 shared between, human, bovin, mouse and variants of histone H3 from other organisms. kinetics:Kd wild type H3 tail peptide = 3.8E-7m in presence of 0.15mM CoA. In absence of CoA = 3.0E-4M|kinetics:Kd phosphorylated Thr-12 H3 tail peptide = 1.4E-8m in presence of 0.15mM CoA. In absence of CoA = 7.4E-4M.|figure legend:6B|kinetics:Kd phosphorylated Ser-11 H3 tail peptide = 1.3E-8m in presence of 0.15mM CoA.|kinetics:Kd phosphorylated Ser-11/Thr-12 H3 tail peptide = 2.0E-8m in presence of 0.15mM CoA.|comment:In the absence of CoA, binding affinities between GCN5 and the peptide forms was significantly reduced.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/03/05 2014/10/16 rogid:Y8SHidiW4dJo0oxEDksur8MC/L0559292 rogid:6M86IQcphd/YS8g0BNmUqxkx7Bk-1 intact-crc:60D7EF4E280D6233|rigid:53mZnKUFshryIZ2hr86XGouNo04 false sufficient binding region:100-255(IPR000182) O-phospho-L-threonine:12-12 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)