#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97756 uniprotkb:P68511 intact:EBI-7277672|uniprotkb:Q794E3|uniprotkb:Q64572|intact:MINT-1203156 intact:EBI-444647|uniprotkb:P11576|uniprotkb:P70198|ensembl:ENSRNOP00000075701 psi-mi:kkcc1_rat(display_long)|uniprotkb:Camkk1(gene name)|psi-mi:Camkk1(display_short)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym) psi-mi:1433f_rat(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7795707|mint:MINT-6491204|imex:IM-11538-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P97756|rgd:62023|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_113850.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1CKK|reactome:R-RNO-111932|reactome:R-RNO-442729|reactome:R-RNO-9619229|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-6491206(identity) rgd:3978|refseq:NP_037184.1|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-5625740|go:"GO:0006886"(intracellular protein transport)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|ensembl:ENSRNOG00000055471(gene)|ensembl:ENSRNOT00000085735(transcript)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68511|reactome:R-RNO-111447|dip:DIP-299N|mint:MINT-6491207(identity) - function:Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death|comment:mint - figure legend:F1A|comment:Interaction is stronger upon forskolin stimulation|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2008/04/01 2014/10/16 rogid:6d6zkDJgWyPXtcxgtgzZHFyZa4g10116 rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10116 intact-crc:8C46056A834BF523|rigid:R54e97ZvgCrrqotb5ezBfVBsSKw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97756 uniprotkb:P35213 intact:EBI-7277672|uniprotkb:Q794E3|uniprotkb:Q64572|intact:MINT-1203156 intact:EBI-917309|ensembl:ENSRNOP00000016981 psi-mi:kkcc1_rat(display_long)|uniprotkb:Camkk1(gene name)|psi-mi:Camkk1(display_short)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym) psi-mi:1433b_rat(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Prepronerve growth factor RNH-1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7795720|mint:MINT-6491236|imex:IM-11538-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P97756|rgd:62023|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_113850.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1CKK|reactome:R-RNO-111932|reactome:R-RNO-442729|reactome:R-RNO-9619229|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-6491242(identity) rgd:61998|refseq:NP_062250.1|ensembl:ENSRNOG00000010945(gene)|ensembl:ENSRNOT00000016981(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P35213|reactome:R-RNO-111447|reactome:R-RNO-165159|reactome:R-RNO-166208|reactome:R-RNO-170968|reactome:R-RNO-2028269|reactome:R-RNO-392517|reactome:R-RNO-450385|reactome:R-RNO-450513|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5675221|reactome:R-RNO-75035|reactome:R-RNO-9614399|mint:MINT-6491238(identity) - function:Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death|comment:mint - figure legend:F1B|comment:Interaction occurs upon forskolin stimulation|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2008/04/01 2014/10/16 rogid:6d6zkDJgWyPXtcxgtgzZHFyZa4g10116 rogid:L/MyYCTZ4ws1GPmT1Jyxa7gVcg010116 intact-crc:D73D6A045FC7B248|rigid:8UAljSwQofRKK9aeJMztS1KUgSM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97756 uniprotkb:P62260 intact:EBI-7277672|uniprotkb:Q794E3|uniprotkb:Q64572|intact:MINT-1203156 intact:EBI-356462|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSRNOP00000007100 psi-mi:kkcc1_rat(display_long)|uniprotkb:Camkk1(gene name)|psi-mi:Camkk1(display_short)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym) psi-mi:1433e_rat(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)|uniprotkb:Mitochondrial import stimulation factor L subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7795720|mint:MINT-6491236|imex:IM-11538-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P97756|rgd:62023|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_113850.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1CKK|reactome:R-RNO-111932|reactome:R-RNO-442729|reactome:R-RNO-9619229|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-6491242(identity) rgd:62000|refseq:NP_113791.1|ensembl:ENSRNOG00000005290(gene)|ensembl:ENSRNOT00000007100(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62260|reactome:R-RNO-111447|reactome:R-RNO-2028269|reactome:R-RNO-205025|reactome:R-RNO-2565942|reactome:R-RNO-3371453|reactome:R-RNO-3371511|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-8876198|dip:DIP-37260N|mint:MINT-6491252(identity) - function:Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death|comment:mint - figure legend:F1B|comment:Interaction occurs upon forskolin stimulation|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2008/04/01 2014/10/16 rogid:6d6zkDJgWyPXtcxgtgzZHFyZa4g10116 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10116 intact-crc:D73D6A045FC7B248|rigid:8UAljSwQofRKK9aeJMztS1KUgSM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97756 uniprotkb:P61983 intact:EBI-7277672|uniprotkb:Q794E3|uniprotkb:Q64572|intact:MINT-1203156 intact:EBI-359821|uniprotkb:A0JPM0|uniprotkb:O70457|uniprotkb:Q9UDP2|uniprotkb:P35214|uniprotkb:Q9UN99|ensembl:ENSRNOP00000001954|ensembl:ENSRNOP00000069671 psi-mi:kkcc1_rat(display_long)|uniprotkb:Camkk1(gene name)|psi-mi:Camkk1(display_short)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym) psi-mi:1433g_rat(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7795720|mint:MINT-6491236|imex:IM-11538-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P97756|rgd:62023|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_113850.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1CKK|reactome:R-RNO-111932|reactome:R-RNO-442729|reactome:R-RNO-9619229|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-6491242(identity) rgd:62002|refseq:NP_062249.1|ensembl:ENSRNOG00000001436(gene)|ensembl:ENSRNOT00000001954(transcript)|ensembl:ENSRNOT00000084730(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61983|reactome:R-RNO-111447|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-9614399|refseq:XP_006249246.2|mint:MINT-6491248(identity) - function:Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death|comment:mint - figure legend:F1B|comment:Interaction occurs upon forskolin stimulation|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2008/04/01 2014/10/16 rogid:6d6zkDJgWyPXtcxgtgzZHFyZa4g10116 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10116 intact-crc:D73D6A045FC7B248|rigid:8UAljSwQofRKK9aeJMztS1KUgSM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N5S9 uniprotkb:Q04917 intact:EBI-6424030|ensembl:ENSP00000323118|uniprotkb:Q9BQH3 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:kkcc1_human(display_long)|uniprotkb:CAMKK1(gene name)|psi-mi:CAMKK1(display_short)|uniprotkb:CAMKKA(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7795796|mint:MINT-6491274|imex:IM-11538-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N5S9|rcsb pdb:6CCF|rcsb pdb:6CD6|reactome:R-HSA-111932|reactome:R-HSA-442729|reactome:R-HSA-9619229|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000004660(gene)|ensembl:ENST00000348335(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|refseq:NP_115670.1|refseq:NP_757344.2|refseq:NP_757343.2|refseq:XP_016880709.1|mint:MINT-6491276(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-6491280(identity) - - - figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/01 2014/10/16 rogid:YtdWptyj6Jr8Jx3VMxa5HfQHXWA9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:0A68857BFE8CCEED|rigid:tglaB2x0ow5bZ+25OJ9woun9/Fw false mutation disrupting interaction:458-458,74-74,52-52,475-475(MINT-6491277) glutathione s tranferase tag:?-?(MINT-6491281) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N5S9 uniprotkb:Q04917 intact:EBI-6424030|ensembl:ENSP00000323118|uniprotkb:Q9BQH3 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:kkcc1_human(display_long)|uniprotkb:CAMKK1(gene name)|psi-mi:CAMKK1(display_short)|uniprotkb:CAMKKA(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7795769|mint:MINT-6491259|imex:IM-11538-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N5S9|rcsb pdb:6CCF|rcsb pdb:6CD6|reactome:R-HSA-111932|reactome:R-HSA-442729|reactome:R-HSA-9619229|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000004660(gene)|ensembl:ENST00000348335(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|refseq:NP_115670.1|refseq:NP_757344.2|refseq:NP_757343.2|refseq:XP_016880709.1|mint:MINT-6491262(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-6491261(identity) - - - figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/01 2014/10/16 rogid:YtdWptyj6Jr8Jx3VMxa5HfQHXWA9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:B340DAB54CBA09AC|rigid:tglaB2x0ow5bZ+25OJ9woun9/Fw false mutation decreasing interaction:458-458,108-108,475-475,52-52(MINT-6491270) glutathione s tranferase tag:?-?(MINT-6491265) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N5S9 uniprotkb:Q04917 intact:EBI-6424030|ensembl:ENSP00000323118|uniprotkb:Q9BQH3 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:kkcc1_human(display_long)|uniprotkb:CAMKK1(gene name)|psi-mi:CAMKK1(display_short)|uniprotkb:CAMKKA(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7795850|mint:MINT-6491300|imex:IM-11538-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N5S9|rcsb pdb:6CCF|rcsb pdb:6CD6|reactome:R-HSA-111932|reactome:R-HSA-442729|reactome:R-HSA-9619229|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000004660(gene)|ensembl:ENST00000348335(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|refseq:NP_115670.1|refseq:NP_757344.2|refseq:NP_757343.2|refseq:XP_016880709.1|mint:MINT-6491302(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-6491306(identity) - - - figure legend:F2D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/01 2014/10/16 rogid:YtdWptyj6Jr8Jx3VMxa5HfQHXWA9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:7CEA52AEACD93BBF|rigid:tglaB2x0ow5bZ+25OJ9woun9/Fw false mutation disrupting interaction:475-475(MINT-6491313)|mutation disrupting interaction:74-74(MINT-6491303) glutathione s tranferase tag:?-?(MINT-6491307) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N5S9 uniprotkb:Q04917 intact:EBI-6424030|ensembl:ENSP00000323118|uniprotkb:Q9BQH3 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:kkcc1_human(display_long)|uniprotkb:CAMKK1(gene name)|psi-mi:CAMKK1(display_short)|uniprotkb:CAMKKA(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7795823|mint:MINT-6491287|imex:IM-11538-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N5S9|rcsb pdb:6CCF|rcsb pdb:6CD6|reactome:R-HSA-111932|reactome:R-HSA-442729|reactome:R-HSA-9619229|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000004660(gene)|ensembl:ENST00000348335(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|refseq:NP_115670.1|refseq:NP_757344.2|refseq:NP_757343.2|refseq:XP_016880709.1|mint:MINT-6491293(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-6491289(identity) - - - figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/01 2014/10/16 rogid:YtdWptyj6Jr8Jx3VMxa5HfQHXWA9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:EF4D8459FCE2BF40|rigid:tglaB2x0ow5bZ+25OJ9woun9/Fw false mutation disrupting interaction:475-475,108-108,74-74,52-52(MINT-6491294) glutathione s tranferase tag:?-?(MINT-6491290) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N5S9 uniprotkb:Q04917 intact:EBI-6424030|ensembl:ENSP00000323118|uniprotkb:Q9BQH3 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:kkcc1_human(display_long)|uniprotkb:CAMKK1(gene name)|psi-mi:CAMKK1(display_short)|uniprotkb:CAMKKA(gene name synonym)|uniprotkb:CaM-kinase IV kinase(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase alpha(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ichimura et al. (2008) pubmed:18242179|imex:IM-11538|mint:MINT-6491196 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7795942|mint:MINT-6491322|imex:IM-11538-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N5S9|rcsb pdb:6CCF|rcsb pdb:6CD6|reactome:R-HSA-111932|reactome:R-HSA-442729|reactome:R-HSA-9619229|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSG00000004660(gene)|ensembl:ENST00000348335(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|refseq:NP_115670.1|refseq:NP_757344.2|refseq:NP_757343.2|refseq:XP_016880709.1|mint:MINT-6491324(identity) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-6491328(identity) - - - figure legend:F2D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/04/01 2014/10/16 rogid:YtdWptyj6Jr8Jx3VMxa5HfQHXWA9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:BAE916648F261874|rigid:tglaB2x0ow5bZ+25OJ9woun9/Fw false mutation disrupting interaction:475-475(MINT-6491334)|mutation disrupting interaction:74-74(MINT-6491325) flag tag:?-?(MINT-6491329) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)