#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94804	uniprotkb:O94804	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791045|mint:MINT-6505319|imex:IM-11553-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6505321(identity)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6505321(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F2 SF2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	intact-crc:1272887FB5632471|rigid:ku9RAmoGs2c2w8vYwC/5FOskVBs	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H2G2	uniprotkb:Q9H2G2	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791054|mint:MINT-6505322|imex:IM-11553-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6505324(identity)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6505324(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:SF2 F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	intact-crc:CBF5CD6B64B5F23A|rigid:9qfkvm1J/oO1GhR5XX4awisbpNc	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96017	uniprotkb:O96017	intact:EBI-1180783|uniprotkb:Q6QA03|uniprotkb:Q6QA04|uniprotkb:Q6QA05|uniprotkb:Q6QA06|uniprotkb:Q6QA07|uniprotkb:Q6QA08|uniprotkb:Q6QA10|uniprotkb:Q6QA11|uniprotkb:Q6QA12|uniprotkb:Q6QA13|uniprotkb:Q9HCQ8|uniprotkb:Q9UGF0|uniprotkb:Q9UGF1|uniprotkb:B7ZBF3|uniprotkb:B7ZBF4|uniprotkb:B7ZBF5|uniprotkb:Q9HBS5|uniprotkb:A8K3Y9|ensembl:ENSP00000385747|ensembl:ENSP00000386087|ensembl:ENSP00000497000	intact:EBI-1180783|uniprotkb:Q6QA03|uniprotkb:Q6QA04|uniprotkb:Q6QA05|uniprotkb:Q6QA06|uniprotkb:Q6QA07|uniprotkb:Q6QA08|uniprotkb:Q6QA10|uniprotkb:Q6QA11|uniprotkb:Q6QA12|uniprotkb:Q6QA13|uniprotkb:Q9HCQ8|uniprotkb:Q9UGF0|uniprotkb:Q9UGF1|uniprotkb:B7ZBF3|uniprotkb:B7ZBF4|uniprotkb:B7ZBF5|uniprotkb:Q9HBS5|uniprotkb:A8K3Y9|ensembl:ENSP00000385747|ensembl:ENSP00000386087|ensembl:ENSP00000497000	psi-mi:chk2_human(display_long)|uniprotkb:CHEK2(gene name)|psi-mi:CHEK2(display_short)|uniprotkb:CHK2(gene name synonym)|uniprotkb:RAD53(gene name synonym)|uniprotkb:Cds1 homolog(gene name synonym)|uniprotkb:Checkpoint kinase 2(gene name synonym)|uniprotkb:CDS1(gene name synonym)|uniprotkb:CHK2 checkpoint homolog(gene name synonym)	psi-mi:chk2_human(display_long)|uniprotkb:CHEK2(gene name)|psi-mi:CHEK2(display_short)|uniprotkb:CHK2(gene name synonym)|uniprotkb:RAD53(gene name synonym)|uniprotkb:Cds1 homolog(gene name synonym)|uniprotkb:Checkpoint kinase 2(gene name synonym)|uniprotkb:CDS1(gene name synonym)|uniprotkb:CHK2 checkpoint homolog(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791072|mint:MINT-6538431|imex:IM-11553-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016884050.1|refseq:NP_001005735.1|refseq:NP_009125.1|refseq:NP_665861.1|refseq:NP_001244316.1|refseq:XP_011528147.1|dip:DIP-24270N|ensembl:ENSG00000183765(gene)|ensembl:ENST00000404276(transcript)|ensembl:ENST00000405598(transcript)|ensembl:ENST00000650281(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1903416"(response to glycoside)|go:"GO:1903926"(cellular response to bisphenol A)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|mint:O96017|rcsb pdb:1GXC|rcsb pdb:2CN5|rcsb pdb:2CN8|rcsb pdb:2W0J|go:"GO:0090399"(replicative senescence)|rcsb pdb:2W7X|rcsb pdb:2WTC|rcsb pdb:2WTD|rcsb pdb:2XM8|rcsb pdb:2XM9|rcsb pdb:2YCF|rcsb pdb:2YCQ|rcsb pdb:2YCR|rcsb pdb:2YCS|rcsb pdb:2YIQ|rcsb pdb:2YIR|rcsb pdb:2YIT|rcsb pdb:3I6U|rcsb pdb:3I6W|rcsb pdb:3VA4|rcsb pdb:4A9R|rcsb pdb:4A9S|rcsb pdb:4A9T|rcsb pdb:4A9U|rcsb pdb:4BDA|rcsb pdb:4BDB|rcsb pdb:4BDC|rcsb pdb:4BDD|rcsb pdb:4BDE|rcsb pdb:4BDF|rcsb pdb:4BDG|rcsb pdb:4BDH|rcsb pdb:4BDI|rcsb pdb:4BDJ|rcsb pdb:4BDK|reactome:R-HSA-5693565|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75035|rcsb pdb:2WTI|rcsb pdb:2WTJ|rcsb pdb:2XBJ|rcsb pdb:2XK9|mint:MINT-6538433(identity)	refseq:XP_016884050.1|refseq:NP_001005735.1|refseq:NP_009125.1|refseq:NP_665861.1|refseq:NP_001244316.1|refseq:XP_011528147.1|dip:DIP-24270N|ensembl:ENSG00000183765(gene)|ensembl:ENST00000404276(transcript)|ensembl:ENST00000405598(transcript)|ensembl:ENST00000650281(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1903416"(response to glycoside)|go:"GO:1903926"(cellular response to bisphenol A)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|mint:O96017|rcsb pdb:1GXC|rcsb pdb:2CN5|rcsb pdb:2CN8|rcsb pdb:2W0J|go:"GO:0090399"(replicative senescence)|rcsb pdb:2W7X|rcsb pdb:2WTC|rcsb pdb:2WTD|rcsb pdb:2XM8|rcsb pdb:2XM9|rcsb pdb:2YCF|rcsb pdb:2YCQ|rcsb pdb:2YCR|rcsb pdb:2YCS|rcsb pdb:2YIQ|rcsb pdb:2YIR|rcsb pdb:2YIT|rcsb pdb:3I6U|rcsb pdb:3I6W|rcsb pdb:3VA4|rcsb pdb:4A9R|rcsb pdb:4A9S|rcsb pdb:4A9T|rcsb pdb:4A9U|rcsb pdb:4BDA|rcsb pdb:4BDB|rcsb pdb:4BDC|rcsb pdb:4BDD|rcsb pdb:4BDE|rcsb pdb:4BDF|rcsb pdb:4BDG|rcsb pdb:4BDH|rcsb pdb:4BDI|rcsb pdb:4BDJ|rcsb pdb:4BDK|reactome:R-HSA-5693565|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75035|rcsb pdb:2WTI|rcsb pdb:2WTJ|rcsb pdb:2XBJ|rcsb pdb:2XK9|mint:MINT-6538433(identity)	-	-	-	figure legend:SF2 F2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:LaDEJtqjPoEJZoj1f6vlZiiaZoI9606	rogid:LaDEJtqjPoEJZoj1f6vlZiiaZoI9606	intact-crc:F77A603D3864EA41|rigid:4gp2G7Z07IkNQHYNUuzRvBiIiQw	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43293	uniprotkb:O43293	intact:EBI-77293|uniprotkb:A0AVN4|uniprotkb:B3KQE2|uniprotkb:Q05JY4|ensembl:ENSP00000301264|ensembl:ENSP00000442973	intact:EBI-77293|uniprotkb:A0AVN4|uniprotkb:B3KQE2|uniprotkb:Q05JY4|ensembl:ENSP00000301264|ensembl:ENSP00000442973	psi-mi:dapk3_human(display_long)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)	psi-mi:dapk3_human(display_long)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791063|mint:MINT-6505347|imex:IM-11553-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001339.1|refseq:XP_005259565.1|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870|mint:O43293|rcsb pdb:1YRP|rcsb pdb:2J90|rcsb pdb:3BHY|rcsb pdb:3BQR|rcsb pdb:5A6N|rcsb pdb:5A6O|rcsb pdb:5VJA|reactome:R-HSA-418889|mint:MINT-6505349(identity)	refseq:NP_001339.1|refseq:XP_005259565.1|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870|mint:O43293|rcsb pdb:1YRP|rcsb pdb:2J90|rcsb pdb:3BHY|rcsb pdb:3BQR|rcsb pdb:5A6N|rcsb pdb:5A6O|rcsb pdb:5VJA|reactome:R-HSA-418889|mint:MINT-6505349(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F2 SF2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606	rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606	intact-crc:13F60686369F03CE|rigid:Kcxs851tb7Rf+Qs/cxfqy9YYMAI	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H2G2	uniprotkb:Q9H2G2	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791129|mint:MINT-6538487|imex:IM-11553-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6538489(identity)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6538489(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4C F4D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	intact-crc:CCD8279768B6554C|rigid:9qfkvm1J/oO1GhR5XX4awisbpNc	false	mutation disrupting interaction:185-185(MINT-6538495)	mutation disrupting interaction:185-185(MINT-6538495)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94804	uniprotkb:O94804	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791091|mint:MINT-6538437|imex:IM-11553-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6538439(identity)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6538439(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4A|kinetics:kd 140 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	intact-crc:32FB49FD8E80D89D|rigid:ku9RAmoGs2c2w8vYwC/5FOskVBs	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43293	uniprotkb:O43293	intact:EBI-77293|uniprotkb:A0AVN4|uniprotkb:B3KQE2|uniprotkb:Q05JY4|ensembl:ENSP00000301264|ensembl:ENSP00000442973	intact:EBI-77293|uniprotkb:A0AVN4|uniprotkb:B3KQE2|uniprotkb:Q05JY4|ensembl:ENSP00000301264|ensembl:ENSP00000442973	psi-mi:dapk3_human(display_long)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)	psi-mi:dapk3_human(display_long)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791101|mint:MINT-6538449|imex:IM-11553-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001339.1|refseq:XP_005259565.1|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870|mint:O43293|rcsb pdb:1YRP|rcsb pdb:2J90|rcsb pdb:3BHY|rcsb pdb:3BQR|rcsb pdb:5A6N|rcsb pdb:5A6O|rcsb pdb:5VJA|reactome:R-HSA-418889|mint:MINT-6538451(identity)	refseq:NP_001339.1|refseq:XP_005259565.1|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016605"(PML body)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042870|mint:O43293|rcsb pdb:1YRP|rcsb pdb:2J90|rcsb pdb:3BHY|rcsb pdb:3BQR|rcsb pdb:5A6N|rcsb pdb:5A6O|rcsb pdb:5VJA|reactome:R-HSA-418889|mint:MINT-6538451(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4|kinetics:kd 270 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606	rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606	intact-crc:1B83D42F6068D1EF|rigid:Kcxs851tb7Rf+Qs/cxfqy9YYMAI	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94804	uniprotkb:O94804	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	intact:EBI-3951541|uniprotkb:A6ND35|uniprotkb:B2R8F5|uniprotkb:Q9UIW4|intact:EBI-28977778|ensembl:ENSP00000176763|uniprotkb:B3KMY1|uniprotkb:Q6NSK0	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:stk10_human(display_long)|uniprotkb:STK10(gene name)|psi-mi:STK10(display_short)|uniprotkb:LOK(gene name synonym)|uniprotkb:Lymphocyte-oriented kinase(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791172|mint:MINT-6538479|imex:IM-11553-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6538481(identity)	ensembl:ENSP00000176763|ensembl:ENSG00000072786(gene)|ensembl:ENST00000176763(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071593"(lymphocyte aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000401"(regulation of lymphocyte migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|interpro:IPR042743|refseq:NP_005981.3|rcsb pdb:2J7T|rcsb pdb:4AOT|rcsb pdb:4BC6|rcsb pdb:4EQU|rcsb pdb:4USD|rcsb pdb:4USE|rcsb pdb:5AJQ|rcsb pdb:5OWQ|rcsb pdb:5OWR|rcsb pdb:6EIM|rcsb pdb:6GTT|rcsb pdb:6HXF|rcsb pdb:6I2Y|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|mint:O94804|mint:MINT-6538481(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	rogid:6B9/kXefiqOkUpwC5woZNbWRco49606	intact-crc:1FD80AAA89BF456A|rigid:ku9RAmoGs2c2w8vYwC/5FOskVBs	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96017	uniprotkb:O96017	intact:EBI-1180783|uniprotkb:Q6QA03|uniprotkb:Q6QA04|uniprotkb:Q6QA05|uniprotkb:Q6QA06|uniprotkb:Q6QA07|uniprotkb:Q6QA08|uniprotkb:Q6QA10|uniprotkb:Q6QA11|uniprotkb:Q6QA12|uniprotkb:Q6QA13|uniprotkb:Q9HCQ8|uniprotkb:Q9UGF0|uniprotkb:Q9UGF1|uniprotkb:B7ZBF3|uniprotkb:B7ZBF4|uniprotkb:B7ZBF5|uniprotkb:Q9HBS5|uniprotkb:A8K3Y9|ensembl:ENSP00000385747|ensembl:ENSP00000386087|ensembl:ENSP00000497000	intact:EBI-1180783|uniprotkb:Q6QA03|uniprotkb:Q6QA04|uniprotkb:Q6QA05|uniprotkb:Q6QA06|uniprotkb:Q6QA07|uniprotkb:Q6QA08|uniprotkb:Q6QA10|uniprotkb:Q6QA11|uniprotkb:Q6QA12|uniprotkb:Q6QA13|uniprotkb:Q9HCQ8|uniprotkb:Q9UGF0|uniprotkb:Q9UGF1|uniprotkb:B7ZBF3|uniprotkb:B7ZBF4|uniprotkb:B7ZBF5|uniprotkb:Q9HBS5|uniprotkb:A8K3Y9|ensembl:ENSP00000385747|ensembl:ENSP00000386087|ensembl:ENSP00000497000	psi-mi:chk2_human(display_long)|uniprotkb:CHEK2(gene name)|psi-mi:CHEK2(display_short)|uniprotkb:CHK2(gene name synonym)|uniprotkb:RAD53(gene name synonym)|uniprotkb:Cds1 homolog(gene name synonym)|uniprotkb:Checkpoint kinase 2(gene name synonym)|uniprotkb:CDS1(gene name synonym)|uniprotkb:CHK2 checkpoint homolog(gene name synonym)	psi-mi:chk2_human(display_long)|uniprotkb:CHEK2(gene name)|psi-mi:CHEK2(display_short)|uniprotkb:CHK2(gene name synonym)|uniprotkb:RAD53(gene name synonym)|uniprotkb:Cds1 homolog(gene name synonym)|uniprotkb:Checkpoint kinase 2(gene name synonym)|uniprotkb:CDS1(gene name synonym)|uniprotkb:CHK2 checkpoint homolog(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791154|mint:MINT-6538460|imex:IM-11553-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016884050.1|refseq:NP_001005735.1|refseq:NP_009125.1|refseq:NP_665861.1|refseq:NP_001244316.1|refseq:XP_011528147.1|dip:DIP-24270N|ensembl:ENSG00000183765(gene)|ensembl:ENST00000404276(transcript)|ensembl:ENST00000405598(transcript)|ensembl:ENST00000650281(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1903416"(response to glycoside)|go:"GO:1903926"(cellular response to bisphenol A)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|mint:O96017|rcsb pdb:1GXC|rcsb pdb:2CN5|rcsb pdb:2CN8|rcsb pdb:2W0J|go:"GO:0090399"(replicative senescence)|rcsb pdb:2W7X|rcsb pdb:2WTC|rcsb pdb:2WTD|rcsb pdb:2XM8|rcsb pdb:2XM9|rcsb pdb:2YCF|rcsb pdb:2YCQ|rcsb pdb:2YCR|rcsb pdb:2YCS|rcsb pdb:2YIQ|rcsb pdb:2YIR|rcsb pdb:2YIT|rcsb pdb:3I6U|rcsb pdb:3I6W|rcsb pdb:3VA4|rcsb pdb:4A9R|rcsb pdb:4A9S|rcsb pdb:4A9T|rcsb pdb:4A9U|rcsb pdb:4BDA|rcsb pdb:4BDB|rcsb pdb:4BDC|rcsb pdb:4BDD|rcsb pdb:4BDE|rcsb pdb:4BDF|rcsb pdb:4BDG|rcsb pdb:4BDH|rcsb pdb:4BDI|rcsb pdb:4BDJ|rcsb pdb:4BDK|reactome:R-HSA-5693565|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75035|rcsb pdb:2WTI|rcsb pdb:2WTJ|rcsb pdb:2XBJ|rcsb pdb:2XK9|mint:MINT-6538462(identity)	refseq:XP_016884050.1|refseq:NP_001005735.1|refseq:NP_009125.1|refseq:NP_665861.1|refseq:NP_001244316.1|refseq:XP_011528147.1|dip:DIP-24270N|ensembl:ENSG00000183765(gene)|ensembl:ENST00000404276(transcript)|ensembl:ENST00000405598(transcript)|ensembl:ENST00000650281(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1903416"(response to glycoside)|go:"GO:1903926"(cellular response to bisphenol A)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|mint:O96017|rcsb pdb:1GXC|rcsb pdb:2CN5|rcsb pdb:2CN8|rcsb pdb:2W0J|go:"GO:0090399"(replicative senescence)|rcsb pdb:2W7X|rcsb pdb:2WTC|rcsb pdb:2WTD|rcsb pdb:2XM8|rcsb pdb:2XM9|rcsb pdb:2YCF|rcsb pdb:2YCQ|rcsb pdb:2YCR|rcsb pdb:2YCS|rcsb pdb:2YIQ|rcsb pdb:2YIR|rcsb pdb:2YIT|rcsb pdb:3I6U|rcsb pdb:3I6W|rcsb pdb:3VA4|rcsb pdb:4A9R|rcsb pdb:4A9S|rcsb pdb:4A9T|rcsb pdb:4A9U|rcsb pdb:4BDA|rcsb pdb:4BDB|rcsb pdb:4BDC|rcsb pdb:4BDD|rcsb pdb:4BDE|rcsb pdb:4BDF|rcsb pdb:4BDG|rcsb pdb:4BDH|rcsb pdb:4BDI|rcsb pdb:4BDJ|rcsb pdb:4BDK|reactome:R-HSA-5693565|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-69473|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75035|rcsb pdb:2WTI|rcsb pdb:2WTJ|rcsb pdb:2XBJ|rcsb pdb:2XK9|mint:MINT-6538462(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:LaDEJtqjPoEJZoj1f6vlZiiaZoI9606	rogid:LaDEJtqjPoEJZoj1f6vlZiiaZoI9606	intact-crc:6F0764AB33D0FF61|rigid:4gp2G7Z07IkNQHYNUuzRvBiIiQw	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H2G2	uniprotkb:Q9H2G2	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Pike et al. (2008)	pubmed:18239682|imex:IM-11553|mint:MINT-6505313	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7791163|mint:MINT-6538465|imex:IM-11553-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6538467(identity)	refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|mint:MINT-6538467(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:F4B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/04/09	2014/10/16	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606	intact-crc:DC53B4E337A118BF|rigid:9qfkvm1J/oO1GhR5XX4awisbpNc	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)