#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49711 uniprotkb:Q14683 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stedman et al. (2008) pubmed:18219272|imex:IM-11544|mint:MINT-6492388 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7786940|mint:MINT-6492397|imex:IM-11544-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|mint:MINT-6492400(identity) ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N|mint:MINT-6492399(identity) go:"GO:0005634"(nucleus) - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bcbl_1)|taxid:9606(Homo sapiens lymphoma cell line) - 2008/04/04 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:D309DCD68FB08E00|rigid:Ce+Ws+GTxZ+2mjaPC8fMfYTmSXk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49711 uniprotkb:O60216 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Stedman et al. (2008) pubmed:18219272|imex:IM-11544|mint:MINT-6492388 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7786954|mint:MINT-6492407|imex:IM-11544-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|mint:MINT-6492412(identity) ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N|mint:MINT-6492410(identity) go:"GO:0005634"(nucleus) - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-bcbl_1)|taxid:9606(Homo sapiens lymphoma cell line) - 2008/04/04 2014/10/16 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 intact-crc:10CE1E7DD7C80D7A|rigid:hq9ooXON0PrqLg+DvVm0wJrJgEQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)