#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7TNJ9 uniprotkb:P84092 intact:EBI-7772187|intact:UNK-5494601|intact:MINT-4571497 intact:EBI-297693|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSRNOP00000070202 psi-mi:q7tnj9_rat(display_long) psi-mi:ap2m1_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7772202|mint:MINT-6179750|imex:IM-11527-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|interpro:IPR031232|mint:Q7TNJ9|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0030100"(regulation of endocytosis)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR036168|mint:MINT-6179752(identity) go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84092|rcsb pdb:1BW8|rcsb pdb:1BXX|rcsb pdb:1HES|rcsb pdb:1I31|rcsb pdb:2BP5|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2PR9|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:3H85|rcsb pdb:3ML6|rcsb pdb:4UQI|rcsb pdb:5C7Z|rcsb pdb:5FPI|rcsb pdb:5WRK|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:5WRL|rcsb pdb:5WRM|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6RH6|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|ensembl:ENSRNOG00000001709(gene)|ensembl:ENSRNOT00000088821(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|rgd:620135|refseq:NP_446289.1|dip:DIP-29761N|mint:MINT-6179757(identity) go:"GO:0030132"(clathrin coat of coated pit) - - figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-astrocyte)|taxid:10116(Rattus norvegicus astrocyte) - 2008/02/15 2014/10/16 rogid:WGfYfslyYSnxKLa7AjN6BZhWjds10116 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10116 intact-crc:BDC532471366543F|rigid:KnIlYOlGMQXDi1CNzIjUcteP+B8 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q7TNJ9 uniprotkb:P42566 intact:EBI-7772187|intact:UNK-5494601|intact:MINT-4571497 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:q7tnj9_rat(display_long) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7772249|mint:MINT-6179760|imex:IM-11527-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|interpro:IPR031232|mint:Q7TNJ9|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0030100"(regulation of endocytosis)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR036168|mint:MINT-6179765(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179763(identity) go:"GO:0030132"(clathrin coat of coated pit) - - figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-astrocyte)|taxid:10116(Rattus norvegicus astrocyte) - 2008/02/15 2014/10/16 rogid:WGfYfslyYSnxKLa7AjN6BZhWjds10116 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:CD8818C576A6B49D|rigid:JtfUfqc4LY8BNfsCu4qDuDIpKGc false - green fluorescent protein tag:?-?(MINT-6179768)|binding-associated region:1-313(MINT-6179771) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TNJ9 uniprotkb:A7BFV9 intact:EBI-7772187|intact:UNK-5494601|intact:MINT-4571497 intact:EBI-6095043 psi-mi:q7tnj9_rat(display_long) psi-mi:a7bfv9_rat(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7772279|mint:MINT-6179791|imex:IM-11527-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|interpro:IPR031232|mint:Q7TNJ9|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0030100"(regulation of endocytosis)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR036168|mint:MINT-6179801(identity) mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding)|mint:MINT-6179794(identity) - - - figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2008/02/15 2014/10/16 rogid:WGfYfslyYSnxKLa7AjN6BZhWjds10116 rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116 intact-crc:9B25955409002B36|rigid:0hQoPEC9r9QNIoJsPpAQX0KacqA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TNJ9 uniprotkb:P84092 intact:EBI-7772187|intact:UNK-5494601|intact:MINT-4571497 intact:EBI-297693|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSRNOP00000070202 psi-mi:q7tnj9_rat(display_long) psi-mi:ap2m1_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7772279|mint:MINT-6179791|imex:IM-11527-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|interpro:IPR031232|mint:Q7TNJ9|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0030100"(regulation of endocytosis)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR036168|mint:MINT-6179801(identity) go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84092|rcsb pdb:1BW8|rcsb pdb:1BXX|rcsb pdb:1HES|rcsb pdb:1I31|rcsb pdb:2BP5|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2PR9|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:3H85|rcsb pdb:3ML6|rcsb pdb:4UQI|rcsb pdb:5C7Z|rcsb pdb:5FPI|rcsb pdb:5WRK|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:5WRL|rcsb pdb:5WRM|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6RH6|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|ensembl:ENSRNOG00000001709(gene)|ensembl:ENSRNOT00000088821(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|rgd:620135|refseq:NP_446289.1|dip:DIP-29761N|mint:MINT-6179806(identity) - - - figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2008/02/15 2014/10/16 rogid:WGfYfslyYSnxKLa7AjN6BZhWjds10116 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10116 intact-crc:9B25955409002B36|rigid:0hQoPEC9r9QNIoJsPpAQX0KacqA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7772356|mint:MINT-6179779|imex:IM-11527-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179782(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179789(identity) go:"GO:0005886"(plasma membrane) - - figure legend:sF1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nie-115)|taxid:10090(Mus musculus) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:0ACCB3D0DD701F79|rigid:asP8TuKXeU+Yr/GIPk4V4oQyrOU false green fluorescent protein tag:?-?(MINT-6179786)|binding-associated region:1-313(MINT-6179783) ha tag:?-?(MINT-6179845) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P42566 uniprotkb:P21579 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-524909|ensembl:ENSP00000261205|ensembl:ENSP00000376932|ensembl:ENSP00000447575|uniprotkb:Q6AI31 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:syt1_human(display_long)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)|uniprotkb:SYT1(gene name)|psi-mi:SYT1(display_short)|uniprotkb:SYT(gene name synonym)|uniprotkb:SVP65(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7772356|mint:MINT-6179779|imex:IM-11527-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179782(identity) refseq:NP_001129277.1|refseq:NP_001129278.1|refseq:NP_005630.1|ensembl:ENSG00000067715(gene)|ensembl:ENST00000261205(transcript)|ensembl:ENST00000393240(transcript)|ensembl:ENST00000552744(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|refseq:XP_011537012.1|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030424"(axon)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031045"(dense core granule)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060201"(clathrin-sculpted acetylcholine transport vesicle membrane)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070083"(clathrin-sculpted monoamine transport vesicle membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21579|rcsb pdb:2K45|rcsb pdb:2K4A|rcsb pdb:2K8M|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|rcsb pdb:2LHA|rcsb pdb:2N1T|rcsb pdb:2KI6|rcsb pdb:2R83|rcsb pdb:3F00|rcsb pdb:3F01|rcsb pdb:3F04|rcsb pdb:3F05|rcsb pdb:4ISQ|rcsb pdb:4V11|rcsb pdb:6G5F|rcsb pdb:6G5K|rcsb pdb:6QNS|rcsb pdb:6TZ3|rcsb pdb:6U41|rcsb pdb:6U4U|rcsb pdb:6U4W|rcsb pdb:6ZVN|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-5250958|reactome:R-HSA-5250989|reactome:R-HSA-6794361|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-888590|reactome:R-HSA-210500|refseq:XP_016875398.1|dip:DIP-34042N|mint:MINT-6179819(identity) go:"GO:0005886"(plasma membrane) - - figure legend:sF1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nie-115)|taxid:10090(Mus musculus) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:oWQJLjUokM2dCvvO+VHVbHUj/WE9606 intact-crc:0ACCB3D0DD701F79|rigid:asP8TuKXeU+Yr/GIPk4V4oQyrOU false green fluorescent protein tag:?-?(MINT-6179786)|binding-associated region:1-313(MINT-6179783) flag tag:?-?(MINT-6179848) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772437|mint:MINT-6179875|imex:IM-11527-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179881(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179877(identity) - - - figure legend:t1 f3a|kinetics:kd 75 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:78B77EEC0BFE333A|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:1-120(MINT-6179882) binding-associated region:301-340(MINT-6179878) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772396|mint:MINT-6179857|imex:IM-11527-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179860(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179859(identity) - - - figure legend:t1 f3a|kinetics:kd 29.5 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:A79E4617DE738534|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:1-313(MINT-6179867) binding-associated region:301-340(MINT-6179872) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772460|mint:MINT-6179890|imex:IM-11527-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179897(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179892(identity) - - - figure legend:t1 f3a|kinetics:kd 0.16 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:ED1C73F4096BA48F|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:301-340(MINT-6179898) binding-associated region:121-215(MINT-6179893) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772483|mint:MINT-6179905|imex:IM-11527-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179911(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179907(identity) - - - figure legend:t1 f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:798A2E15799F91E1|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:121-215(MINT-6179912) binding-associated region:301-340(MINT-6179908)|mutation disrupting interaction:313-315(MINT-6179919) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772544|mint:MINT-6179923|imex:IM-11527-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179930(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179925(identity) - - - figure legend:t1 f3b|kinetics:kd 7.5 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:1AE2F1A5FB18BA3E|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false mutation decreasing interaction:329-331(MINT-6179931)|binding-associated region:301-340(MINT-6179933) binding-associated region:121-215(MINT-6179926) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772581|mint:MINT-6179941|imex:IM-11527-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179943(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179949(identity) - - - figure legend:t1 f3b|kinetics:kd 6.6 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:045E212BBEED422F|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:312-332(MINT-6179946) binding-associated region:121-215(MINT-6179950) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772675|mint:MINT-6180075|imex:IM-11527-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180081(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180077(identity) - - - kinetics:kd 30.9 micromolar|figure legend:f6c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:B0F48CC7215350B0|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false mutation decreasing interaction:169-169(MINT-6180090)|binding-associated region:121-215(MINT-6180082) binding-associated region:301-340(MINT-6180078) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q9Y6I3 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-713198|intact:EBI-28967658|ensembl:ENSP00000270460|uniprotkb:Q86ST3|uniprotkb:Q9HA18 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:epn1_human(display_long)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)|uniprotkb:EH domain-binding mitotic phosphoprotein(gene name synonym)|uniprotkb:EPN1(gene name)|psi-mi:EPN1(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772650|mint:MINT-6179958|imex:IM-11527-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179960(identity) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048568"(embryonic organ development)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q9Y6I3|rcsb pdb:1INZ|rcsb pdb:1KYD|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000063245(gene)|ensembl:ENST00000270460(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|ensembl:ENST00000085079|ensembl:ENSP00000085079|ensembl:ENSP00000270460|ensembl:ENST00000411543|ensembl:ENSP00000406209|refseq:NP_001123543.1|refseq:NP_001123544.1|refseq:NP_037465.2|refseq:XP_005258886.1|refseq:XP_016882211.1|refseq:XP_011525183.1|mint:MINT-6179965(identity) - - - figure legend:t1 f3b|kinetics:kd 90 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:mp6MIJYGUJryy3Lk5coFqvOt55c9606 intact-crc:468492FF6F4A7436|rigid:24SC2e+EVHR2o6vw7gmnlt/mocs false binding-associated region:121-215(MINT-6179961) binding-associated region:?-?(MINT-6179966) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772765|mint:MINT-6180111|imex:IM-11527-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180117(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180113(identity) - - - figure legend:f6c|kinetics:kd 4.6 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:AB6B9CA306AD4E23|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false mutation decreasing interaction:196-196(MINT-6180121)|binding-associated region:121-215(MINT-6180118) binding-associated region:301-340(MINT-6180114) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772721|mint:MINT-6180093|imex:IM-11527-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180095(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180102(identity) - - - figure legend:f6c|kinetics:kd 4.1 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:EA5DECE121021F15|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false mutation decreasing interaction:193-193(MINT-6180096)|binding-associated region:121-215(MINT-6180098) binding-associated region:301-340(MINT-6180103) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772826|mint:MINT-6180129|imex:IM-11527-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180131(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180138(identity) - - - figure legend:f6c|kinetics:kd 12.5 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:B2D59570B9724C92|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false mutation decreasing interaction:154-154(MINT-6180132)|binding-associated region:121-215(MINT-6180134) binding-associated region:301-340(MINT-6180139) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXE9 uniprotkb:Q9UBC2 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772864|mint:MINT-6180146|imex:IM-11527-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180148(identity) refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1|mint:MINT-6180152(identity) - - - kinetics:kd 0.87 micromolar|figure legend:sf6|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606 intact-crc:795332B764DAFDFE|rigid:KVk92K4F5JxR6L67n1H2hKkPAiQ false binding-associated region:301-340(MINT-6180149) binding-associated region:120-214(MINT-6180153) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H4M9 uniprotkb:Q8WXE9 intact:EBI-490691|uniprotkb:O14611|uniprotkb:Q2M3Q4|uniprotkb:Q9UNR3|ensembl:ENSP00000320516|ensembl:ENSP00000352354 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:ehd1_human(display_long)|uniprotkb:Testilin(gene name synonym)|uniprotkb:CDABP0131(orf name)|uniprotkb:EHD1(gene name)|psi-mi:EHD1(display_short)|uniprotkb:PAST(gene name synonym)|uniprotkb:PAST1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7772998|mint:MINT-6180161|imex:IM-11527-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_006786.2|refseq:XP_011543041.1|refseq:NP_001269373.1|refseq:NP_001269374.1|ensembl:ENSG00000110047(gene)|ensembl:ENST00000320631(transcript)|ensembl:ENST00000359393(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H4M9|rcsb pdb:2JQ6|rcsb pdb:2KFF|rcsb pdb:2KFG|rcsb pdb:2KFH|rcsb pdb:2KSP|reactome:R-HSA-983231|mint:MINT-6180163(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180168(identity) - - - kinetics:kd 23 micromolar|figure legend:sf6|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:txUfRMtv6SbBqKKJ1DVM6K/pj2Y9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:91B5EAF2EF4CE7E6|rigid:lUfK3FISfUPAA2ZB0GEiUySk2QI false binding-associated region:438-534(MINT-6180164) binding-associated region:301-340(MINT-6180169) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96D71 uniprotkb:Q8WXE9 intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7773039|mint:MINT-6180180|imex:IM-11527-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828|mint:MINT-6180182(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180187(identity) - - - figure legend:sf6|kinetics:kd 19 micromolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:378A2E380F6DEA6B|rigid:y+LsunCY/BMnuDa4KgV578xncxg false binding-associated region:226-314(MINT-6180183) binding-associated region:301-340(MINT-6180188) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7773089|mint:MINT-6179977|imex:IM-11527-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6179983(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179979(identity) - - - figure legend:f4 f5|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:9C443B72528F324E|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false binding-associated region:121-215(MINT-6179984) binding-associated region:301-340(MINT-6179980) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773243|mint:MINT-6179996|imex:IM-11527-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6179998(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180002(identity) - - - figure legend:f6d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:B5411B360370C55E|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false ha tag:?-?(MINT-6180007) flag tag:?-?(MINT-6180010)|binding-associated region:121-215(MINT-6180003)|mutation disrupting interaction:154-154(MINT-6180012) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42566 uniprotkb:Q8WXE9 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773289|mint:MINT-6180018|imex:IM-11527-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180020(identity) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180029(identity) - - - figure legend:f6d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/15 2014/10/16 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 intact-crc:51FD6ABAD004B6D7|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false flag tag:?-?(MINT-6180023)|binding-associated region:121-215(MINT-6180025)|mutation disrupting interaction:169-169(MINT-6180021) ha tag:?-?(MINT-6180030) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773317|mint:MINT-6180038|imex:IM-11527-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180040(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180044(identity) - - - figure legend:f6d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:74F1F03308082624|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false ha tag:?-?(MINT-6180041) flag tag:?-?(MINT-6180048)|binding-associated region:217-313(MINT-6180045)|mutation decreasing interaction:266-266(MINT-6180050) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WXE9 uniprotkb:P42566 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rumpf et al. (2008) pubmed:18200045|imex:IM-11527|mint:MINT-6179743 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773380|mint:MINT-6180056|imex:IM-11527-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9|mint:MINT-6180067(identity) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N|mint:MINT-6180058(identity) - - - figure legend:f6d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/15 2014/10/16 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 intact-crc:E3B0B8E42FD987F7|rigid:JqIWSWte8j1PMFeqvQuP7wI/as8 false ha tag:?-?(MINT-6180068) mutation disrupting interaction:169-169(MINT-6180072)|flag tag:?-?(MINT-6180061)|mutation disrupting interaction:154-154(MINT-6180059) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)