#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7Z614 uniprotkb:Q14242 intact:EBI-744896|uniprotkb:A8K9D5|uniprotkb:Q08E98|uniprotkb:Q6P4H2|uniprotkb:Q8IV59|ensembl:ENSP00000332062 intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|ensembl:ENSP00000447752|uniprotkb:B7Z5C7|uniprotkb:J3KMX6 psi-mi:snx20_human(display_long)|uniprotkb:SLIC1(gene name synonym)|uniprotkb:Selectin ligand-interactor cytoplasmic 1(gene name synonym)|uniprotkb:SNX20(gene name)|psi-mi:SNX20(display_short) psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:"MI:0018"(two hybrid) Schaff et al. (2008) pubmed:18196517|imex:IM-19096 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2120239|imex:IM-19096-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138444.1|refseq:NP_699168.1|refseq:NP_878274.1|ensembl:ENSG00000167208(gene)|ensembl:ENST00000330943(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937 refseq:NP_001193538.1|refseq:NP_002997.2|go:"GO:0050901"(leukocyte tethering or rolling)|ensembl:ENSG00000110876(gene)|go:"GO:0050902"(leukocyte adhesive activation)|go:"GO:0071354"(cellular response to interleukin-6)|ensembl:ENST00000550948(transcript)|go:"GO:0001618"(virus receptor activity)|interpro:IPR026195|go:"GO:0001931"(uropod)|rcsb pdb:1G1S|reactome:R-HSA-202733|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|dip:DIP-37668N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/11/28 2014/10/16 rogid:YVqRGdZSr/tNPHjn239y9ikgg049606 rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606 intact-crc:02FE4DF2D6AA7951|rigid:w8FfdfsokJuUVXWchJaMdZf3flE false binding-associated region:72-187 binding-associated region:344-412 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7Z614 uniprotkb:Q14242 intact:EBI-744896|uniprotkb:A8K9D5|uniprotkb:Q08E98|uniprotkb:Q6P4H2|uniprotkb:Q8IV59|ensembl:ENSP00000332062 intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|ensembl:ENSP00000447752|uniprotkb:B7Z5C7|uniprotkb:J3KMX6 psi-mi:snx20_human(display_long)|uniprotkb:SLIC1(gene name synonym)|uniprotkb:Selectin ligand-interactor cytoplasmic 1(gene name synonym)|uniprotkb:SNX20(gene name)|psi-mi:SNX20(display_short) psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schaff et al. (2008) pubmed:18196517|imex:IM-19096 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2120253|imex:IM-19096-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138444.1|refseq:NP_699168.1|refseq:NP_878274.1|ensembl:ENSG00000167208(gene)|ensembl:ENST00000330943(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937 refseq:NP_001193538.1|refseq:NP_002997.2|go:"GO:0050901"(leukocyte tethering or rolling)|ensembl:ENSG00000110876(gene)|go:"GO:0050902"(leukocyte adhesive activation)|go:"GO:0071354"(cellular response to interleukin-6)|ensembl:ENST00000550948(transcript)|go:"GO:0001618"(virus receptor activity)|interpro:IPR026195|go:"GO:0001931"(uropod)|rcsb pdb:1G1S|reactome:R-HSA-202733|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|dip:DIP-37668N - - - figure legend:2A and B|delivery method:Q7Z614; Q14242 transfection|comment:"A SELPLG mutant construct on the background of SELPLG/PSGL360 aa344-370) was generated with the ERM binding sequence mutated (346-SRKGH-350 deletion and Ser358Ala mutation). This mutant exhibited enhanced SNX20/SLIC-1 binding activity."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_6)|taxid:9534(African green monkey kidney cell line) - 2008/11/28 2014/10/16 rogid:YVqRGdZSr/tNPHjn239y9ikgg049606 rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606 intact-crc:B1735C4E55587710|rigid:w8FfdfsokJuUVXWchJaMdZf3flE false - sufficient binding region:344-370 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q7Z614 uniprotkb:Q14242 intact:EBI-744896|uniprotkb:A8K9D5|uniprotkb:Q08E98|uniprotkb:Q6P4H2|uniprotkb:Q8IV59|ensembl:ENSP00000332062 intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|ensembl:ENSP00000447752|uniprotkb:B7Z5C7|uniprotkb:J3KMX6 psi-mi:snx20_human(display_long)|uniprotkb:SLIC1(gene name synonym)|uniprotkb:Selectin ligand-interactor cytoplasmic 1(gene name synonym)|uniprotkb:SNX20(gene name)|psi-mi:SNX20(display_short) psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:"MI:0081"(peptide array) Schaff et al. (2008) pubmed:18196517|imex:IM-19096 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-2120265|imex:IM-19096-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138444.1|refseq:NP_699168.1|refseq:NP_878274.1|ensembl:ENSG00000167208(gene)|ensembl:ENST00000330943(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937 refseq:NP_001193538.1|refseq:NP_002997.2|go:"GO:0050901"(leukocyte tethering or rolling)|ensembl:ENSG00000110876(gene)|go:"GO:0050902"(leukocyte adhesive activation)|go:"GO:0071354"(cellular response to interleukin-6)|ensembl:ENST00000550948(transcript)|go:"GO:0001618"(virus receptor activity)|interpro:IPR026195|go:"GO:0001931"(uropod)|rcsb pdb:1G1S|reactome:R-HSA-202733|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|dip:DIP-37668N - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/28 2014/10/16 rogid:YVqRGdZSr/tNPHjn239y9ikgg049606 rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606 intact-crc:AD9213EACBF9C383|rigid:w8FfdfsokJuUVXWchJaMdZf3flE false glutathione s tranferase tag:?-? binding-associated region:352-362|binding-associated region:389-412 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z614 uniprotkb:Q14242 intact:EBI-744896|uniprotkb:A8K9D5|uniprotkb:Q08E98|uniprotkb:Q6P4H2|uniprotkb:Q8IV59|ensembl:ENSP00000332062 intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|ensembl:ENSP00000447752|uniprotkb:B7Z5C7|uniprotkb:J3KMX6 psi-mi:snx20_human(display_long)|uniprotkb:SLIC1(gene name synonym)|uniprotkb:Selectin ligand-interactor cytoplasmic 1(gene name synonym)|uniprotkb:SNX20(gene name)|psi-mi:SNX20(display_short) psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:"MI:0081"(peptide array) Schaff et al. (2008) pubmed:18196517|imex:IM-19096 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-2120275|imex:IM-19096-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138444.1|refseq:NP_699168.1|refseq:NP_878274.1|ensembl:ENSG00000167208(gene)|ensembl:ENST00000330943(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937 refseq:NP_001193538.1|refseq:NP_002997.2|go:"GO:0050901"(leukocyte tethering or rolling)|ensembl:ENSG00000110876(gene)|go:"GO:0050902"(leukocyte adhesive activation)|go:"GO:0071354"(cellular response to interleukin-6)|ensembl:ENST00000550948(transcript)|go:"GO:0001618"(virus receptor activity)|interpro:IPR026195|go:"GO:0001931"(uropod)|rcsb pdb:1G1S|reactome:R-HSA-202733|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|dip:DIP-37668N - - - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/11/28 2014/10/16 rogid:YVqRGdZSr/tNPHjn239y9ikgg049606 rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606 intact-crc:0B53ED5DFB7DC276|rigid:w8FfdfsokJuUVXWchJaMdZf3flE false binding-associated region:74-191(IPR001683)|glutathione s tranferase tag:?-? binding-associated region:390-412|binding-associated region:352-363 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14242 uniprotkb:Q7Z614 intact:EBI-1030190|uniprotkb:Q12775|uniprotkb:Q6GTW7|uniprotkb:Q8N7J7|uniprotkb:B4DQC3|uniprotkb:A8K2Y0|ensembl:ENSP00000447752|uniprotkb:B7Z5C7|uniprotkb:J3KMX6 intact:EBI-744896|uniprotkb:A8K9D5|uniprotkb:Q08E98|uniprotkb:Q6P4H2|uniprotkb:Q8IV59|ensembl:ENSP00000332062 psi-mi:selpl_human(display_long)|uniprotkb:SELPLG(gene name)|psi-mi:SELPLG(display_short)|uniprotkb:Selectin P ligand(gene name synonym) psi-mi:snx20_human(display_long)|uniprotkb:SLIC1(gene name synonym)|uniprotkb:Selectin ligand-interactor cytoplasmic 1(gene name synonym)|uniprotkb:SNX20(gene name)|psi-mi:SNX20(display_short) psi-mi:"MI:0663"(confocal microscopy) Schaff et al. (2008) pubmed:18196517|imex:IM-19096 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2120309|imex:IM-19096-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193538.1|refseq:NP_002997.2|go:"GO:0050901"(leukocyte tethering or rolling)|ensembl:ENSG00000110876(gene)|go:"GO:0050902"(leukocyte adhesive activation)|go:"GO:0071354"(cellular response to interleukin-6)|ensembl:ENST00000550948(transcript)|go:"GO:0001618"(virus receptor activity)|interpro:IPR026195|go:"GO:0001931"(uropod)|rcsb pdb:1G1S|reactome:R-HSA-202733|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0050900"(leukocyte migration)|dip:DIP-37668N refseq:NP_001138444.1|refseq:NP_699168.1|refseq:NP_878274.1|ensembl:ENSG00000167208(gene)|ensembl:ENST00000330943(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR039937 go:"GO:0005768"(endosome) - - figure legend:6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2008/11/28 2014/10/16 rogid:9UTaluLRA9WEeiqsCXJMkKOmbhc9606 rogid:YVqRGdZSr/tNPHjn239y9ikgg049606 intact-crc:F8B9C2418CEB9E71|rigid:w8FfdfsokJuUVXWchJaMdZf3flE false - enhanced green fluorescent protein tag:?-?|mutation disrupting interaction:116-116 - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)