#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63244	uniprotkb:P22303	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0018"(two hybrid)	Mor et al. (2008)	pubmed:18194455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1769965	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 A, B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/05/02	2014/10/16	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:B42F6D635B2B82EF|rigid:bFbDhbJO29dveqcAQi6HI5y5iRc	false	sufficient binding region:49-279|sufficient binding region:118-317	sufficient binding region:562-614	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06733	uniprotkb:P22303	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0018"(two hybrid)	Mor et al. (2008)	pubmed:18194455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1769977	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 A, B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/05/02	2014/10/16	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:5D1B9F80949FCAB4|rigid:KpELpgOnr5l/PPSJL0gIVQhuT1E	false	sufficient binding region:186-397	sufficient binding region:562-614	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
chebi:"CHEBI:15355"	uniprotkb:P22303	intact:EBI-1769996	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:acetylcholine(display_short)|psi-mi:"CHEBI:15355"(display_long)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1769992	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 C|comment:Incubation with enolase-alpha increased ACHE's acetylcholinesterase activity.|kinetics:"Km = 4.6 E-5 M; Km (in presence of enolase-alpha = 5.5 E-5. Vmax = 12.6 arbitrary units/min; Vmax (in presence of enolase-alpha) = 15 arbitrary units/min."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:13943CE69C0B6676	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22303	uniprotkb:P06733	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1769992	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:1 C|comment:Incubation with enolase-alpha increased ACHE's acetylcholinesterase activity.|kinetics:"Km = 4.6 E-5 M; Km (in presence of enolase-alpha = 5.5 E-5. Vmax = 12.6 arbitrary units/min; Vmax (in presence of enolase-alpha) = 15 arbitrary units/min."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:13943CE69C0B6676	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17835"	uniprotkb:P22303	intact:EBI-1770328	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:2-phospho-d-glyceric acid(display_short)|psi-mi:"CHEBI:17835"(display_long)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770330	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:4 B|comment:"The enolase-alpha activity of enolase-alpha was stimulated by the peptide ARP26 (GMQGPAGSGWEEGSGSPPGVTPLFSP), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-R. The enolase-alpha activity of enolase-alpha was not stimulated by the peptide ASP23 (WSSYMVHWKQFDHYSKQDRCSDL), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-S."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:9E6221B64C45EECE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17835"	uniprotkb:P06733	intact:EBI-1770328	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:2-phospho-d-glyceric acid(display_short)|psi-mi:"CHEBI:17835"(display_long)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770330	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:4 B|comment:"The enolase-alpha activity of enolase-alpha was stimulated by the peptide ARP26 (GMQGPAGSGWEEGSGSPPGVTPLFSP), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-R. The enolase-alpha activity of enolase-alpha was not stimulated by the peptide ASP23 (WSSYMVHWKQFDHYSKQDRCSDL), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-S."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	intact-crc:9E6221B64C45EECE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17835"	intact:EBI-1778797	intact:EBI-1770328	-	psi-mi:2-phospho-d-glyceric acid(display_short)|psi-mi:"CHEBI:17835"(display_long)	psi-mi:human_arp26_peptide(display_short)|psi-mi:EBI-1778797(display_long)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770330	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0327"(peptide)	-	pubmed:18194455(primary-reference)	-	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt	figure legend:4 B|comment:"The enolase-alpha activity of enolase-alpha was stimulated by the peptide ARP26 (GMQGPAGSGWEEGSGSPPGVTPLFSP), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-R. The enolase-alpha activity of enolase-alpha was not stimulated by the peptide ASP23 (WSSYMVHWKQFDHYSKQDRCSDL), which is at the C-terminus of the form of ACHE referred to by the authors as AChE-S."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:gF8CM+Ei3f1RYsiLOeHUMf10n4A9606	intact-crc:9E6221B64C45EECE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15355"	uniprotkb:P22303	intact:EBI-1769996	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:acetylcholine(display_short)|psi-mi:"CHEBI:15355"(display_long)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1776416	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 C|comment:Incubation with GNB2L1 increased ACHE's acetylcholinesterase activity.|kinetics:"Km = 4.6 E-5 M; Km (in presence of GNB2L1) = 4.8 E-5 M. Vmax = 12.6 arbitrary units/min; Vmax (in presence of GNB2L1) =  15 arbitrary units/min."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:4757B029CB892098	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22303	uniprotkb:P63244	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1776416	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N	-	-	-	figure legend:1 C|comment:Incubation with GNB2L1 increased ACHE's acetylcholinesterase activity.|kinetics:"Km = 4.6 E-5 M; Km (in presence of GNB2L1) = 4.8 E-5 M. Vmax = 12.6 arbitrary units/min; Vmax (in presence of GNB2L1) =  15 arbitrary units/min."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606	intact-crc:4757B029CB892098	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15355"	uniprotkb:P22303	intact:EBI-1769996	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:acetylcholine(display_short)|psi-mi:"CHEBI:15355"(display_long)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0415"(enzymatic study)	Mor et al. (2008)	pubmed:18194455	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1776426	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 C|kinetics:Km = 4.6 E-5 M. Vmax = 12.6 arbitrary units/min.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/05/02	2014/10/16	-	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:685B78AEF5AA68E6	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22303	uniprotkb:P68040	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mor et al. (2008)	pubmed:18194455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770081	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	-	-	-	figure legend:1 D|comment:"This interaction occurred in testicular homogenates from TgR mice, which overexpress human ACHE (hAChE-R)."|expression level:P22303 overexpressed|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis)	-	2008/05/02	2014/10/16	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	intact-crc:B8B5624601D771A6|rigid:L9fWEGRbs6CSEsJPji2mYXFRpNw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17182	uniprotkb:P22303	intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7	intact:EBI-1637793|uniprotkb:Q16169|uniprotkb:Q86TM9|uniprotkb:Q9BXP7|uniprotkb:A4D2E2|uniprotkb:Q29S23|uniprotkb:Q2M324|uniprotkb:Q504V3|uniprotkb:Q86YX9|uniprotkb:D6W5X7|uniprotkb:B7ZKZ0|uniprotkb:Q53F46|ensembl:ENSP00000394976|ensembl:ENSP00000414858|ensembl:ENSP00000241069	psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)	psi-mi:aces_human(display_long)|uniprotkb:ACHE(gene name)|psi-mi:ACHE(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mor et al. (2008)	pubmed:18194455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770088	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2	refseq:XP_011514530.1|refseq:XP_011514531.1|refseq:NP_000656.1|refseq:NP_056646.1|ensembl:ENSG00000087085|refseq:XP_006716058.1|refseq:NP_001289550.1|refseq:NP_001289551.1|refseq:NP_001269378.1|dip:DIP-1119N|ensembl:ENSG00000087085(gene)|ensembl:ENST00000241069(transcript)|ensembl:ENST00000412389(transcript)|ensembl:ENST00000428317(transcript)|go:"GO:0001507"(acetylcholine catabolic process in synaptic cleft)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007416"(synapse assembly)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1B41|rcsb pdb:1F8U|rcsb pdb:1PUV|rcsb pdb:1PUW|rcsb pdb:1VZJ|rcsb pdb:2CLJ|rcsb pdb:2X8B|rcsb pdb:3LII|rcsb pdb:4BDT|rcsb pdb:4EY4|rcsb pdb:4EY5|rcsb pdb:4EY6|rcsb pdb:4EY7|rcsb pdb:4EY8|rcsb pdb:4M0E|rcsb pdb:4M0F|rcsb pdb:4PQE|rcsb pdb:5FOQ|rcsb pdb:5FPQ|rcsb pdb:5HF5|rcsb pdb:5HF6|rcsb pdb:5HF8|rcsb pdb:5HF9|rcsb pdb:5HFA|rcsb pdb:6CQT|rcsb pdb:6CQU|rcsb pdb:6CQV|rcsb pdb:6CQW|rcsb pdb:6CQX|rcsb pdb:6CQY|rcsb pdb:6CQZ|rcsb pdb:6F25|rcsb pdb:6NEA|rcsb pdb:6NTG|rcsb pdb:6NTH|rcsb pdb:6NTK|rcsb pdb:6NTL|rcsb pdb:6NTM|rcsb pdb:6NTN|rcsb pdb:6NTO|rcsb pdb:6O4W|rcsb pdb:6O4X|rcsb pdb:6O50|rcsb pdb:6O52|rcsb pdb:6O5R|rcsb pdb:6O5S|rcsb pdb:6O5V|rcsb pdb:6O66|rcsb pdb:6O69|rcsb pdb:6U34|rcsb pdb:6U37|rcsb pdb:6U3P|rcsb pdb:6WUV|rcsb pdb:6WUY|rcsb pdb:6WUZ|rcsb pdb:6WV1|rcsb pdb:6WVC|rcsb pdb:6WVO|rcsb pdb:6WVP|rcsb pdb:6WVQ|rcsb pdb:6ZWE|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085	-	-	-	figure legend:1 D|expression level:P22303 overexpressed|comment:"This interaction occurred  in testicular homogenates from TgR mice, which overexpress human ACHE (hAChE-R)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis)	-	2008/05/02	2014/10/16	rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090	rogid:7JpI1FosTcbuldkkW4tg62j1piE9606	intact-crc:69F981E1D3550EB6|rigid:U/o3PwhgqxioXHZPGvoguZx3rW0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P68040	uniprotkb:Q9JJP2-1	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	intact:EBI-2325338|ensembl:ENSMUSP00000101269	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:q9jjp2-1(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)|uniprotkb:Alpha(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mor et al. (2008)	pubmed:18194455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770199	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	intact:EBI-1770138(isoform-parent)|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000105644(transcript)	-	-	-	figure legend:3 D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis)	-	2008/05/02	2014/10/16	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	rogid:XUKqmk0uMp4NvED+uCHZJ+XzunQ10090	intact-crc:B9B0B9A3099EE68E|rigid:XlwsgClT+TgLjOWEd8PiCXyh91o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P68040	uniprotkb:Q9JJP2-2	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	intact:EBI-2325342|ensembl:ENSMUSP00000114418	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:q9jjp2-2(display_long)|uniprotkb:Tp73(gene name)|psi-mi:Tp73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:Trp73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)|uniprotkb:dN-Alpha(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mor et al. (2008)	pubmed:18194455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1770199	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	intact:EBI-1770138(isoform-parent)|ensembl:ENSMUSG00000029026(gene)|ensembl:ENSMUST00000133533(transcript)	-	-	isoform-comment:Produced by alternative promoter usage.	figure legend:3 D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis)	-	2008/05/02	2014/10/16	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	rogid:Lw84sml147EgJZG4z9fIPmAtQ0U10090	intact-crc:B9B0B9A3099EE68E|rigid:XlwsgClT+TgLjOWEd8PiCXyh91o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)