#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P63038 uniprotkb:O15527 intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4 intact:EBI-721675|uniprotkb:O00390|uniprotkb:O00670|uniprotkb:O00705|uniprotkb:O14876|uniprotkb:O95488|uniprotkb:P78554|uniprotkb:Q9BW42|uniprotkb:Q9UIK0|uniprotkb:Q9UIK1|uniprotkb:Q9UIK2|uniprotkb:Q9UL34|uniprotkb:Q9Y2C0|uniprotkb:Q9Y2C1|uniprotkb:Q9Y6C3|uniprotkb:Q9Y6C4|uniprotkb:A8K1E3|intact:EBI-2560746|ensembl:ENSP00000342851 psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym) psi-mi:ogg1_human(display_long)|uniprotkb:OGG1(gene name)|psi-mi:OGG1(display_short)|uniprotkb:MMH(gene name synonym)|uniprotkb:MUTM(gene name synonym)|uniprotkb:OGH1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Oka et al. (2008) pubmed:18188152|imex:IM-11523|mint:MINT-6179495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7759360|mint:MINT-6179502|imex:IM-11523-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N|mint:MINT-6179504(identity) refseq:NP_002533.1|refseq:NP_058212.1|refseq:NP_058213.1|refseq:NP_058214.1|refseq:NP_058434.1|refseq:NP_058436.1|refseq:NP_058437.1|refseq:NP_058438.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008534"(oxidized purine nucleobase lesion DNA N-glycosylase activity)|go:"GO:0009314"(response to radiation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0032355"(response to estradiol)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034039"(8-oxo-7,8-dihydroguanine DNA N-glycosylase activity)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045007"(depurination)|go:"GO:0045008"(depyrimidination)|go:"GO:0045471"(response to ethanol)|go:"GO:0051593"(response to folic acid)|go:"GO:0071276"(cellular response to cadmium ion)|ensembl:ENSG00000114026(gene)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901291"(negative regulation of double-strand break repair via single-strand annealing)|interpro:IPR003265(HhH-GPD)|interpro:IPR004577(8-oxoguanine DNA-glycosylase)|ensembl:ENST00000344629(transcript)|go:"GO:0002526"(acute inflammatory response)|interpro:IPR011257(DNA glycosylase)|interpro:IPR012904(8-oxoguanine DNA glycosylase, N-terminal)|interpro:IPR023170|mint:O15527|rcsb pdb:1EBM|rcsb pdb:1FN7|rcsb pdb:1HU0|go:"GO:0003684"(damaged DNA binding)|rcsb pdb:1KO9|rcsb pdb:1LWV|rcsb pdb:1LWW|rcsb pdb:1LWY|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|rcsb pdb:1M3H|rcsb pdb:1M3Q|rcsb pdb:1N39|rcsb pdb:1N3A|rcsb pdb:1N3C|rcsb pdb:1YQK|rcsb pdb:1YQL|rcsb pdb:1YQM|rcsb pdb:1YQR|rcsb pdb:2I5W|rcsb pdb:2NOB|rcsb pdb:2NOE|rcsb pdb:2NOF|rcsb pdb:2NOH|rcsb pdb:2NOI|rcsb pdb:2NOL|rcsb pdb:2NOZ|rcsb pdb:2XHI|rcsb pdb:3IH7|rcsb pdb:3KTU|rcsb pdb:5AN4|rcsb pdb:6RLW|rcsb pdb:6W0M|rcsb pdb:6W0R|rcsb pdb:6W13|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-110357|reactome:R-HSA-5649702|reactome:R-HSA-9656255|reactome:R-HSA-9656256|reactome:R-HSA-9657050|mint:MINT-6179505(identity) go:"GO:0005739"(mitochondrion) - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2008/02/14 2014/10/16 rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090 rogid:9cIkOQcFUo6djvZxPtXiDOs8fKQ9606 intact-crc:03B9E0134423BD46|rigid:dJxw8vX/PCA7YfKFJtKVPq5FHfA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0707"(anti tag immunostaining)