#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49687	uniprotkb:Q04491	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580629|imex:IM-11984-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	crc64:A94388B4B9CB77FE	figure legend:1 C|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states in the yeast-yeast complex, with a small amount of hetero-octamers observed at high concentrations.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	intact-crc:589364A50FF51DBE|rigid:W7eMp+LCTO4QmAKYF1jRKboEM9s	false	sufficient binding region:730-1060	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49687	uniprotkb:Q04491	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580636|imex:IM-11984-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	crc64:A94388B4B9CB77FE	figure legend:1 C|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states in the yeast-yeast complex, with a small amount of hetero-octamers observed at high concentrations.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	intact-crc:8CCE12824BC85C07|rigid:W7eMp+LCTO4QmAKYF1jRKboEM9s	false	sufficient binding region:730-1060	-	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04491	uniprotkb:P49687	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580645|imex:IM-11984-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	psi-mi:"MI:0469"(intact)	crc64:A94388B4B9CB77FE	crc64:59399D86BB553030	figure legend:1 C|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states in the yeast-yeast complex, with a small amount of hetero-octamers observed at high concentrations.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:9474FECCC3B2DF74|rigid:W7eMp+LCTO4QmAKYF1jRKboEM9s	false	-	sufficient binding region:730-1060	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P49687	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580653|imex:IM-11984-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	psi-mi:"MI:0469"(intact)	-	crc64:59399D86BB553030	figure legend:1 D, E|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states for the chimeric human-yeast  complex, although a higher ratio of hetero-octamer and even an additional heterododecamer peak existed\" as compared to the yeast-yeast complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:C131FB27B22E6F54|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:1-316	sufficient binding region:730-1060	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P49687	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580661|imex:IM-11984-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	psi-mi:"MI:0469"(intact)	-	crc64:59399D86BB553030	figure legend:1 D, E|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states for the chimeric human-yeast  complex, although a higher ratio of hetero-octamer and even an additional heterododecamer peak existed\" as compared to the yeast-yeast complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:905C69F73D8F8E7A|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:1-316	sufficient binding region:730-1060	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49687	uniprotkb:P55735	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580669|imex:IM-11984-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	-	figure legend:1 D|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states for the chimeric human-yeast  complex, although a higher ratio of hetero-octamer and even an additional heterododecamer peak existed\" as compared to the yeast-yeast complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:3CEE0A6D5CDB882D|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:730-1060	-	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49687	uniprotkb:P55735	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580677|imex:IM-11984-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	-	figure legend:1 D|comment:"The authors state that \"there was a dynamic equilibrium between heterodimeric and heterotetrameric states for the chimeric human-yeast  complex, although a higher ratio of hetero-octamer and even an additional heterododecamer peak existed\" as compared to the yeast-yeast complex."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:0758D1ED5F9A9045|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:730-1060	-	6	6	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P55735	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580729|imex:IM-11984-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	psi-mi:"MI:0469"(intact)	-	-	figure legend:S2 A, C|comment:"The truncated hSec13 (aa 1 3-16) exists mainly as a monomer with barely detectable levels of dimer."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:853FEDBA98D28941|rigid:XNa2NLmuNPqRCgwDwfsNGrZ9EwY	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04491	uniprotkb:Q04491	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580735|imex:IM-11984-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	psi-mi:"MI:0469"(intact)	crc64:A94388B4B9CB77FE	crc64:A94388B4B9CB77FE	figure legend:S2 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	intact-crc:31D5F1C5ABC85542|rigid:6mv+88/xduCfKHSMgbR6RHVfYxs	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46673	uniprotkb:P53011	intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3	intact:EBI-16940|uniprotkb:D6VU45|ensemblfungi:YGL100W	psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym)	psi-mi:seh1_yeast(display_long)|uniprotkb:SEH1(gene name)|psi-mi:SEH1(display_short)|uniprotkb:Nuclear pore protein SEH1(gene name synonym)|uniprotkb:SEC13 homolog 1(gene name synonym)|uniprotkb:YGL100W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580856|imex:IM-11984-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N	refseq:NP_011415.1|sgd:S000003068|ensemblfungi:YGL100W(gene)|ensemblfungi:YGL100W_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:6X08|mint:P53011|dip:DIP-4193N	psi-mi:"MI:0469"(intact)	crc64:4C0A4AD3DB57A023	crc64:EAF75B9DE074106B	figure legend:6|comment:"The authors state that \"We found that the Seh1-Nup85 complex forms a dynamic equilibrium between heterotetramers and hetero-octamers, very similar to the Sec13-Nup145C complex. In contrast to the Sec13-Nup145C, the Seh1-Nup85 dimers are tightly associated, yielding a sharp heterotetramer peak even at lower concentrations, with no heterodimers detectable.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292	rogid:iDa21gDjE9D0KACE0DdN+kcZP4Y559292	intact-crc:38D49517FB88FE4E|rigid:aXBBZbDhQq32fdU++9ixvlofQ1U	false	binding-associated region:1-570	-	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53011	uniprotkb:P46673	intact:EBI-16940|uniprotkb:D6VU45|ensemblfungi:YGL100W	intact:EBI-12345|ensemblfungi:YJR042W|uniprotkb:D6VWL3	psi-mi:seh1_yeast(display_long)|uniprotkb:SEH1(gene name)|psi-mi:SEH1(display_short)|uniprotkb:Nuclear pore protein SEH1(gene name synonym)|uniprotkb:SEC13 homolog 1(gene name synonym)|uniprotkb:YGL100W(locus name)	psi-mi:nup85_yeast(display_long)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:RAT9(gene name synonym)|uniprotkb:YJR042W(locus name)|uniprotkb:J1624(orf name)|uniprotkb:Nuclear pore protein NUP85(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580888|imex:IM-11984-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011415.1|sgd:S000003068|ensemblfungi:YGL100W(gene)|ensemblfungi:YGL100W_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:6X08|mint:P53011|dip:DIP-4193N	ensemblfungi:YJR042W(gene)|ensemblfungi:YJR042W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR011502(Nucleoporin, Nup85-like)|rcsb pdb:3EWE|rcsb pdb:3F3F|rcsb pdb:3F3G|rcsb pdb:3F3P|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6X08|refseq:NP_012576.1|sgd:S000003803|mint:P46673|dip:DIP-5818N	psi-mi:"MI:0469"(intact)	crc64:EAF75B9DE074106B	crc64:4C0A4AD3DB57A023	figure legend:6|comment:"The authors state that \"We found that the Seh1-Nup85 complex forms a dynamic equilibrium between heterotetramers and hetero-octamers, very similar to the Sec13-Nup145C complex. In contrast to the Sec13-Nup145C, the Seh1-Nup85 dimers are tightly associated, yielding a sharp heterotetramer peak even at lower concentrations, with no heterodimers detectable.\""|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:iDa21gDjE9D0KACE0DdN+kcZP4Y559292	rogid:XmACeptHS3SlfgccMUpRYxEA3sI559292	intact-crc:DEDA617329E0593D|rigid:aXBBZbDhQq32fdU++9ixvlofQ1U	false	-	binding-associated region:1-570	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P49687	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580693|imex:IM-11984-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	psi-mi:"MI:0469"(intact)	-	crc64:59399D86BB553030	figure legend:1 F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:9F0D70DB40E52B9F|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:1-316	sufficient binding region:730-1060	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P49687	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580701|imex:IM-11984-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	psi-mi:"MI:0469"(intact)	-	crc64:59399D86BB553030	figure legend:1 F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:8F4E4997466564A2|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:1-316	sufficient binding region:730-1060	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49687	uniprotkb:Q04491	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-16529|ensemblfungi:YLR208W|uniprotkb:D6VYK9	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_yeast(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:ANU3(gene name synonym)|uniprotkb:YLR208W(locus name)|uniprotkb:L8167.4(orf name)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580715|imex:IM-11984-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	refseq:NP_013309.1|sgd:S000004198|ensemblfungi:YLR208W(gene)|ensemblfungi:YLR208W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0071944"(cell periphery)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|rcsb pdb:2PM6|rcsb pdb:2PM7|rcsb pdb:2PM9|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3MZK|rcsb pdb:3MZL|rcsb pdb:4BZJ|rcsb pdb:4BZK|rcsb pdb:4XMM|rcsb pdb:4XMN|rcsb pdb:6ZG5|rcsb pdb:6ZG6|rcsb pdb:6ZL0|reactome:R-SCE-204005|dip:DIP-1826N|mint:Q04491	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	crc64:A94388B4B9CB77FE	figure legend:S1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:HcczRFhRumq3rcXnLE1Pq2PuyXE559292	intact-crc:497BD3309AAAABF3|rigid:W7eMp+LCTO4QmAKYF1jRKboEM9s	false	sufficient binding region:830-1160	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P49687	uniprotkb:P55735	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580721|imex:IM-11984-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	psi-mi:"MI:0469"(intact)	crc64:59399D86BB553030	-	figure legend:S1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:5874014632B78BEA|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:830-1160	sufficient binding region:1-316	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P49687	uniprotkb:P55735	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580766|imex:IM-11984-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	wwpdb:3BG1(primary-reference)	crc64:59399D86BB553030	-	figure legend:2, Table S1|3d-resolution:3.0 A|complex-properties:"M.W. = 400 kDa (approx.). Sec13-Nup145C hetero-octamer forms a slightly bent rod with overall dimensions of approximately 285 A x 100 A x 50 A."|3d-r-factors:"Rwork/Rfree (%) = 24.7/28.9"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	intact-crc:6EB287EF36C6C373|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:830-1160	sufficient binding region:1-316	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55735	uniprotkb:P49687	intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1	intact:EBI-11730|ensemblfungi:YGL092W|uniprotkb:D6VU53	psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym)	psi-mi:nu145_yeast(display_long)|uniprotkb:YGL092W(locus name)|uniprotkb:NUP145(gene name)|psi-mi:NUP145(display_short)|uniprotkb:RAT10(gene name synonym)|uniprotkb:Nuclear pore protein NUP145(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hsia et al. (2007)	imex:IM-11984|pubmed:18160040	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1580832|imex:IM-11984-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N	ensemblfungi:YGL092W(gene)|ensemblfungi:YGL092W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051664"(nuclear pore localization)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|rcsb pdb:3BG0|rcsb pdb:3BG1|rcsb pdb:3IKO|rcsb pdb:3JRO|rcsb pdb:3JRP|rcsb pdb:3KEP|rcsb pdb:3KES|rcsb pdb:4XMM|rcsb pdb:4XMN|go:"GO:0031509"(subtelomeric heterochromatin assembly)|refseq:NP_011423.1|sgd:S000003060|mint:P49687|dip:DIP-2074N	wwpdb:3BG0(primary-reference)	-	crc64:59399D86BB553030	figure legend:2, Table S2|3d-resolution:3.15 A|complex-properties:"M.W. = 400 kDa (approx.). Sec13-Nup145C hetero-octamer forms a slightly bent rod with overall dimensions of approximately 285 A x 100 A x 50 A."|3d-r-factors:"Rwork/Rfree (%) = 24.7/29.2"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/15	2014/10/16	rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606	rogid:IUF7IKaLKMDpFCcuLTjLBB7rD9U559292	intact-crc:9735F06282B79863|rigid:iaojsUFlGmgOnHfz09Gbc+vpzls	false	sufficient binding region:1-316	sufficient binding region:830-1160	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)