#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01227 uniprotkb:P24761 intact:EBI-7736422|intact:MINT-6740407|uniprotkb:Q76ZL8 intact:EBI-7736404|intact:MINT-6740609|uniprotkb:Q76ZP2 psi-mi:b5_vaccw(display_long)|uniprotkb:PS/HR(gene name)|psi-mi:PS/HR(display_short)|uniprotkb:Plaque-size/host range protein(gene name synonym)|uniprotkb:B5R(orf name)|uniprotkb:VACWR187(locus name) psi-mi:a34_vaccw(display_long)|uniprotkb:VACWR157(locus name)|uniprotkb:A34R(orf name)|uniprotkb:SALL4R(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Perdiguero et al. (2008) pubmed:18094186|mint:MINT-6735233 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7736440|mint:MINT-6741146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0055036"(virion membrane)|go:"GO:0001848"(complement binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0045916"(negative regulation of complement activation)|mint:Q01227|refseq:YP_233069.1|interpro:IPR011176(Complement control protein, vaccinia C3L)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|mint:MINT-6741150(identity)|uniprotkb:Q01227(Q01227) go:"GO:0016021"(integral component of membrane)|go:"GO:0055036"(virion membrane)|mint:P24761|interpro:IPR016187(C-type lectin fold)|interpro:IPR001304(C-type lectin)|refseq:YP_233039.1|interpro:IPR016186(C-type lectin-like)|mint:MINT-6741147(identity)|uniprotkb:P24761(P24761) - function:Regulation of plaque size and host range|comment:mint function:Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell|comment:mint figure legend:F2, F4, F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/28 2014/10/16 rogid:AmY2MSPFHQtFmU2fDk0NQO4BdX010254 rogid:1+Wyxxu2Le5uC14+2acAHTFWJpg10254 intact-crc:9804F6D0FFE0087A|rigid:cifu+D76iG8sYFLHUB8hKHqe92g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24761 uniprotkb:P68619 intact:EBI-7736404|intact:MINT-6740609|uniprotkb:Q76ZP2 intact:EBI-7133540|uniprotkb:Q76ZP0|intact:MINT-6740391|uniprotkb:P21059 psi-mi:a34_vaccw(display_long)|uniprotkb:VACWR157(locus name)|uniprotkb:A34R(orf name)|uniprotkb:SALL4R(orf name) psi-mi:a36_vaccw(display_long)|uniprotkb:VACWR159(locus name)|uniprotkb:A36R(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Perdiguero et al. (2008) pubmed:18094186|mint:MINT-6735233 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7736453|mint:MINT-6741152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0055036"(virion membrane)|mint:P24761|interpro:IPR016187(C-type lectin fold)|interpro:IPR001304(C-type lectin)|refseq:YP_233039.1|interpro:IPR016186(C-type lectin-like)|mint:MINT-6741155(identity)|uniprotkb:P24761(P24761) mint:P68619|go:"GO:0016021"(integral component of membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|interpro:IPR010274(Orthopoxvirus A36R)|refseq:YP_233041.1|mint:MINT-6741153(identity)|uniprotkb:P68619(P68619) - function:Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell|comment:mint comment:mint|comment:homomint figure legend:F2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/28 2014/10/16 rogid:1+Wyxxu2Le5uC14+2acAHTFWJpg10254 rogid:aKux1p7Vh0X1KKi8L0KI+Jni4Aw10254 intact-crc:39A084AB09543E7B|rigid:KYVGiW8Tchw2zwI8lHQAulbBtDU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24761 uniprotkb:P68617 intact:EBI-7736404|intact:MINT-6740609|uniprotkb:Q76ZP2 intact:EBI-7133633|uniprotkb:Q76ZP3|intact:MINT-6740399|uniprotkb:P21056 psi-mi:a34_vaccw(display_long)|uniprotkb:VACWR157(locus name)|uniprotkb:A34R(orf name)|uniprotkb:SALL4R(orf name) psi-mi:a33_vaccw(display_long)|uniprotkb:VACWR156(locus name)|uniprotkb:A33R(orf name) psi-mi:"MI:0027"(cosedimentation) Perdiguero et al. (2008) pubmed:18094186|mint:MINT-6735233 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7736544|mint:MINT-6741169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0055036"(virion membrane)|mint:P24761|interpro:IPR016187(C-type lectin fold)|interpro:IPR001304(C-type lectin)|refseq:YP_233039.1|interpro:IPR016186(C-type lectin-like)|mint:MINT-6741170(identity)|uniprotkb:P24761(P24761) interpro:IPR016186(C-type lectin-like)|mint:P68617|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0033644"(host cell membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:3K7B|refseq:YP_233038.1|interpro:IPR009238(Chordopoxvirus A33R)|mint:MINT-6741172(identity)|uniprotkb:P68617(P68617) - function:Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell|comment:mint comment:mint figure legend:F8|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/28 2014/10/16 rogid:1+Wyxxu2Le5uC14+2acAHTFWJpg10254 rogid:Fpzuvc3vwsgelhJXG0WHBN95YIc10254 intact-crc:BAAB0ECF532DDEF3|rigid:23Tu0RyXNH/Bf1RackPPm/A+IUs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24761 uniprotkb:Q01227 intact:EBI-7736404|intact:MINT-6740609|uniprotkb:Q76ZP2 intact:EBI-7736422|intact:MINT-6740407|uniprotkb:Q76ZL8 psi-mi:a34_vaccw(display_long)|uniprotkb:VACWR157(locus name)|uniprotkb:A34R(orf name)|uniprotkb:SALL4R(orf name) psi-mi:b5_vaccw(display_long)|uniprotkb:PS/HR(gene name)|psi-mi:PS/HR(display_short)|uniprotkb:Plaque-size/host range protein(gene name synonym)|uniprotkb:B5R(orf name)|uniprotkb:VACWR187(locus name) psi-mi:"MI:0027"(cosedimentation) Perdiguero et al. (2008) pubmed:18094186|mint:MINT-6735233 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7736477|mint:MINT-6741159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0055036"(virion membrane)|mint:P24761|interpro:IPR016187(C-type lectin fold)|interpro:IPR001304(C-type lectin)|refseq:YP_233039.1|interpro:IPR016186(C-type lectin-like)|mint:MINT-6741160(identity)|uniprotkb:P24761(P24761) go:"GO:0055036"(virion membrane)|go:"GO:0001848"(complement binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0045916"(negative regulation of complement activation)|mint:Q01227|refseq:YP_233069.1|interpro:IPR011176(Complement control protein, vaccinia C3L)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|mint:MINT-6741162(identity)|uniprotkb:Q01227(Q01227) - function:Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell|comment:mint function:Regulation of plaque size and host range|comment:mint figure legend:F8|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/28 2014/10/16 rogid:1+Wyxxu2Le5uC14+2acAHTFWJpg10254 rogid:AmY2MSPFHQtFmU2fDk0NQO4BdX010254 intact-crc:201F50BA8E1ED5C1|rigid:cifu+D76iG8sYFLHUB8hKHqe92g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24761 uniprotkb:P04021 intact:EBI-7736404|intact:MINT-6740609|uniprotkb:Q76ZP2 intact:EBI-7736497|uniprotkb:Q76ZW5|intact:MINT-6740445 psi-mi:a34_vaccw(display_long)|uniprotkb:VACWR157(locus name)|uniprotkb:A34R(orf name)|uniprotkb:SALL4R(orf name) psi-mi:f13_vaccw(display_long)|uniprotkb:Palmitoylated EV membrane protein(gene name synonym)|uniprotkb:F13L(orf name)|uniprotkb:VACWR052(locus name)|uniprotkb:37 kDa protein(gene name synonym)|uniprotkb:p37K(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Perdiguero et al. (2008) pubmed:18094186|mint:MINT-6735233 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7736490|mint:MINT-6741164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0055036"(virion membrane)|mint:P24761|interpro:IPR016187(C-type lectin fold)|interpro:IPR001304(C-type lectin)|refseq:YP_233039.1|interpro:IPR016186(C-type lectin-like)|mint:MINT-6741167(identity)|uniprotkb:P24761(P24761) go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019031"(viral envelope)|go:"GO:0036338"(viral membrane)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|mint:P04021|interpro:IPR032803|refseq:YP_232934.1|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|mint:MINT-6741165(identity)|uniprotkb:P04021(P04021) - function:Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell|comment:mint function:This protein is the major antigen on the envelope of extracellular vaccinia virus|comment:mint figure legend:F8|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation taxid:-3(unknown)|taxid:-3(Unknown) - 2008/07/28 2014/10/16 rogid:1+Wyxxu2Le5uC14+2acAHTFWJpg10254 rogid:+llgJRF/Z3taZZVnd0tajY0ZIQw10254 intact-crc:F58598540ED2CE37|rigid:yOkItr29QwXvbwEWIMXDn/zonhA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)