#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:G5EEN4	uniprotkb:X5M5N0	intact:EBI-7713242|ensemblmetazoa:Y59A8B.23a.1|uniprotkb:B5QSI7|uniprotkb:F9UKV1|intact:MINT-6175745	intact:EBI-6540721|intact:EBI-7713269|intact:UNK-5972656|uniprotkb:H2L282|uniprotkb:H2L283|uniprotkb:H2L284|uniprotkb:H2L285|uniprotkb:H2L286|uniprotkb:H2L288|uniprotkb:H2L289|uniprotkb:H2L290|uniprotkb:H2L291|uniprotkb:H2L292|uniprotkb:H2L293|uniprotkb:Q18657|uniprotkb:Q8I127|uniprotkb:X5LPT1|uniprotkb:X5LPT5|uniprotkb:X5LV40|uniprotkb:X5LV44|uniprotkb:X5LX64|uniprotkb:X5M5N6|uniprotkb:X5M8T1|uniprotkb:X5M8T5|ensemblmetazoa:C46C2.1n.1|ensemblmetazoa:C46C2.1n.2	psi-mi:gck3_caeel(display_long)|uniprotkb:gck-3(gene name)|psi-mi:gck-3(display_short)|uniprotkb:STE20-like serine/threonine kinase(gene name synonym)|uniprotkb:Y59A8B.23(orf name)	psi-mi:wnk_caeel(display_long)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:C46C2.1(orf name)|uniprotkb:wnk-1(gene name)|psi-mi:wnk-1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hisamoto et al. (2008)	pubmed:18049475|imex:IM-13954|mint:MINT-6175684	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7713263|mint:MINT-6175757|imex:IM-13954-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:G5EEN4|ensemblmetazoa:WBGene00013355(gene)|ensemblmetazoa:Y59A8B.23a.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:0106311"|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001129918.1|refseq:NP_001256762.1|wormbase:Y59A8B.23b|wormbase:Y59A8B.23c|refseq:NP_507517.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR024678|interpro:IPR017441(Protein kinase ATP binding, conserved site)|uniprotkb:Q9GRY2(uniprot-removed-ac)|interpro:IPR011009(Protein kinase-like)|wormbase:Y59A8B.23a|mint:MINT-6175759(identity)	wormbase:C46C2.1b|wormbase:C46C2.1c|wormbase:C46C2.1d|wormbase:C46C2.1e|wormbase:C46C2.1f|wormbase:C46C2.1g|wormbase:C46C2.1h|wormbase:C46C2.1i|wormbase:C46C2.1j|wormbase:C46C2.1k|wormbase:C46C2.1l|wormbase:C46C2.1m|wormbase:C46C2.1n|wormbase:C46C2.1o|wormbase:C46C2.1p|wormbase:C46C2.1q|wormbase:C46C2.1r|wormbase:C46C2.1s|wormbase:C46C2.1t|wormbase:C46C2.1u|wormbase:C46C2.1v|ensemblmetazoa:C46C2.1n.1(transcript)|ensemblmetazoa:C46C2.1n.2(transcript)|ensemblmetazoa:WBGene00006941(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|reactome:R-CEL-2672351|refseq:NP_001255367.1|refseq:NP_001255368.1|refseq:NP_001255369.1|refseq:NP_001255370.1|refseq:NP_001255371.1|refseq:NP_001255372.1|refseq:NP_001255373.1|refseq:NP_001255374.1|refseq:NP_001255375.1|refseq:NP_001255376.1|refseq:NP_001255377.1|refseq:NP_001294032.1|refseq:NP_001294033.1|refseq:NP_001294034.1|refseq:NP_001294035.1|refseq:NP_001294036.1|refseq:NP_001294037.1|refseq:NP_001294038.1|refseq:NP_001294039.1|refseq:NP_001294040.1|refseq:NP_501603.3|refseq:NP_872075.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|wormbase:C46C2.1a|mint:X5M5N0|mint:MINT-6175760(identity)	-	comment:mint	-	figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/02/07	2015/07/18	rogid:PreB3E8wmkM77xDXcqc4mvdxfc06239	rogid:H7Hnb9aFa8HucS/PFDKM0vcW8vA6239	intact-crc:8A2DFF70BDAA3206|rigid:i/XNi1FmCUjQ6BhhRlVPQnF7ws8	false	t7 tag:?-?(MINT-6175769)|binding-associated region:500-596(MINT-6175809)	flag tag:?-?(MINT-6175762)|mutation decreasing interaction:1133-1133(MINT-6175765)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EEN4	uniprotkb:X5M5N0	intact:EBI-7713242|ensemblmetazoa:Y59A8B.23a.1|uniprotkb:B5QSI7|uniprotkb:F9UKV1|intact:MINT-6175745	intact:EBI-6540721|intact:EBI-7713269|intact:UNK-5972656|uniprotkb:H2L282|uniprotkb:H2L283|uniprotkb:H2L284|uniprotkb:H2L285|uniprotkb:H2L286|uniprotkb:H2L288|uniprotkb:H2L289|uniprotkb:H2L290|uniprotkb:H2L291|uniprotkb:H2L292|uniprotkb:H2L293|uniprotkb:Q18657|uniprotkb:Q8I127|uniprotkb:X5LPT1|uniprotkb:X5LPT5|uniprotkb:X5LV40|uniprotkb:X5LV44|uniprotkb:X5LX64|uniprotkb:X5M5N6|uniprotkb:X5M8T1|uniprotkb:X5M8T5|ensemblmetazoa:C46C2.1n.1|ensemblmetazoa:C46C2.1n.2	psi-mi:gck3_caeel(display_long)|uniprotkb:gck-3(gene name)|psi-mi:gck-3(display_short)|uniprotkb:STE20-like serine/threonine kinase(gene name synonym)|uniprotkb:Y59A8B.23(orf name)	psi-mi:wnk_caeel(display_long)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:C46C2.1(orf name)|uniprotkb:wnk-1(gene name)|psi-mi:wnk-1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hisamoto et al. (2008)	pubmed:18049475|imex:IM-13954|mint:MINT-6175684	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7713368|mint:MINT-6175773|imex:IM-13954-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:G5EEN4|ensemblmetazoa:WBGene00013355(gene)|ensemblmetazoa:Y59A8B.23a.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:0106311"|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001129918.1|refseq:NP_001256762.1|wormbase:Y59A8B.23b|wormbase:Y59A8B.23c|refseq:NP_507517.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR024678|interpro:IPR017441(Protein kinase ATP binding, conserved site)|uniprotkb:Q9GRY2(uniprot-removed-ac)|interpro:IPR011009(Protein kinase-like)|wormbase:Y59A8B.23a|mint:MINT-6175775(identity)	wormbase:C46C2.1b|wormbase:C46C2.1c|wormbase:C46C2.1d|wormbase:C46C2.1e|wormbase:C46C2.1f|wormbase:C46C2.1g|wormbase:C46C2.1h|wormbase:C46C2.1i|wormbase:C46C2.1j|wormbase:C46C2.1k|wormbase:C46C2.1l|wormbase:C46C2.1m|wormbase:C46C2.1n|wormbase:C46C2.1o|wormbase:C46C2.1p|wormbase:C46C2.1q|wormbase:C46C2.1r|wormbase:C46C2.1s|wormbase:C46C2.1t|wormbase:C46C2.1u|wormbase:C46C2.1v|ensemblmetazoa:C46C2.1n.1(transcript)|ensemblmetazoa:C46C2.1n.2(transcript)|ensemblmetazoa:WBGene00006941(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|reactome:R-CEL-2672351|refseq:NP_001255367.1|refseq:NP_001255368.1|refseq:NP_001255369.1|refseq:NP_001255370.1|refseq:NP_001255371.1|refseq:NP_001255372.1|refseq:NP_001255373.1|refseq:NP_001255374.1|refseq:NP_001255375.1|refseq:NP_001255376.1|refseq:NP_001255377.1|refseq:NP_001294032.1|refseq:NP_001294033.1|refseq:NP_001294034.1|refseq:NP_001294035.1|refseq:NP_001294036.1|refseq:NP_001294037.1|refseq:NP_001294038.1|refseq:NP_001294039.1|refseq:NP_001294040.1|refseq:NP_501603.3|refseq:NP_872075.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|wormbase:C46C2.1a|mint:X5M5N0|mint:MINT-6175779(identity)	-	comment:mint	-	figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/02/07	2015/07/18	rogid:PreB3E8wmkM77xDXcqc4mvdxfc06239	rogid:H7Hnb9aFa8HucS/PFDKM0vcW8vA6239	intact-crc:DECFE16EC349CFB3|rigid:i/XNi1FmCUjQ6BhhRlVPQnF7ws8	false	t7 tag:?-?(MINT-6175776)|binding-associated region:500-596(MINT-6175786)	flag tag:?-?(MINT-6175782)|mutation decreasing interaction:1122-1122(MINT-6175780)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EEN4	uniprotkb:X5M5N0	intact:EBI-7713242|ensemblmetazoa:Y59A8B.23a.1|uniprotkb:B5QSI7|uniprotkb:F9UKV1|intact:MINT-6175745	intact:EBI-6540721|intact:EBI-7713269|intact:UNK-5972656|uniprotkb:H2L282|uniprotkb:H2L283|uniprotkb:H2L284|uniprotkb:H2L285|uniprotkb:H2L286|uniprotkb:H2L288|uniprotkb:H2L289|uniprotkb:H2L290|uniprotkb:H2L291|uniprotkb:H2L292|uniprotkb:H2L293|uniprotkb:Q18657|uniprotkb:Q8I127|uniprotkb:X5LPT1|uniprotkb:X5LPT5|uniprotkb:X5LV40|uniprotkb:X5LV44|uniprotkb:X5LX64|uniprotkb:X5M5N6|uniprotkb:X5M8T1|uniprotkb:X5M8T5|ensemblmetazoa:C46C2.1n.1|ensemblmetazoa:C46C2.1n.2	psi-mi:gck3_caeel(display_long)|uniprotkb:gck-3(gene name)|psi-mi:gck-3(display_short)|uniprotkb:STE20-like serine/threonine kinase(gene name synonym)|uniprotkb:Y59A8B.23(orf name)	psi-mi:wnk_caeel(display_long)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:C46C2.1(orf name)|uniprotkb:wnk-1(gene name)|psi-mi:wnk-1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hisamoto et al. (2008)	pubmed:18049475|imex:IM-13954|mint:MINT-6175684	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7713395|mint:MINT-6175791|imex:IM-13954-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:G5EEN4|ensemblmetazoa:WBGene00013355(gene)|ensemblmetazoa:Y59A8B.23a.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:0106311"|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001129918.1|refseq:NP_001256762.1|wormbase:Y59A8B.23b|wormbase:Y59A8B.23c|refseq:NP_507517.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR024678|interpro:IPR017441(Protein kinase ATP binding, conserved site)|uniprotkb:Q9GRY2(uniprot-removed-ac)|interpro:IPR011009(Protein kinase-like)|wormbase:Y59A8B.23a|mint:MINT-6175799(identity)	wormbase:C46C2.1b|wormbase:C46C2.1c|wormbase:C46C2.1d|wormbase:C46C2.1e|wormbase:C46C2.1f|wormbase:C46C2.1g|wormbase:C46C2.1h|wormbase:C46C2.1i|wormbase:C46C2.1j|wormbase:C46C2.1k|wormbase:C46C2.1l|wormbase:C46C2.1m|wormbase:C46C2.1n|wormbase:C46C2.1o|wormbase:C46C2.1p|wormbase:C46C2.1q|wormbase:C46C2.1r|wormbase:C46C2.1s|wormbase:C46C2.1t|wormbase:C46C2.1u|wormbase:C46C2.1v|ensemblmetazoa:C46C2.1n.1(transcript)|ensemblmetazoa:C46C2.1n.2(transcript)|ensemblmetazoa:WBGene00006941(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|reactome:R-CEL-2672351|refseq:NP_001255367.1|refseq:NP_001255368.1|refseq:NP_001255369.1|refseq:NP_001255370.1|refseq:NP_001255371.1|refseq:NP_001255372.1|refseq:NP_001255373.1|refseq:NP_001255374.1|refseq:NP_001255375.1|refseq:NP_001255376.1|refseq:NP_001255377.1|refseq:NP_001294032.1|refseq:NP_001294033.1|refseq:NP_001294034.1|refseq:NP_001294035.1|refseq:NP_001294036.1|refseq:NP_001294037.1|refseq:NP_001294038.1|refseq:NP_001294039.1|refseq:NP_001294040.1|refseq:NP_501603.3|refseq:NP_872075.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|wormbase:C46C2.1a|mint:X5M5N0|mint:MINT-6175793(identity)	-	comment:mint	-	figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/02/07	2015/07/18	rogid:PreB3E8wmkM77xDXcqc4mvdxfc06239	rogid:H7Hnb9aFa8HucS/PFDKM0vcW8vA6239	intact-crc:641D0633D4916CA7|rigid:i/XNi1FmCUjQ6BhhRlVPQnF7ws8	false	binding-associated region:500-596(MINT-6175800)|t7 tag:?-?(MINT-6175802)	mutation disrupting interaction:1133-1133,1122-1122(MINT-6175796)|flag tag:?-?(MINT-6175794)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)