#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P70232	uniprotkb:Q9JMB8	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-7703151|ensembl:ENSMUSP00000086623|ensembl:ENSMUSP00000124025|intact:MINT-6439843|uniprotkb:Q8C6X1	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:cntn6_mouse(display_long)|uniprotkb:Cntn6(gene name)|psi-mi:Cntn6(display_short)|uniprotkb:Neural recognition molecule NB-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703176|mint:MINT-6439870|imex:IM-11535-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439872(identity)	ensembl:ENSMUSG00000030092(gene)|ensembl:ENSMUST00000089215(transcript)|ensembl:ENSMUST00000162872(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR036116|interpro:IPR036179|mint:Q9JMB8|rcsb pdb:5E55|rcsb pdb:5E5U|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_017177167.1|refseq:XP_017177168.1|refseq:NP_059079.2|refseq:XP_006506444.1|refseq:XP_006506445.1|refseq:XP_006506446.1|refseq:XP_006506447.1|mint:MINT-6439873(identity)	-	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	function:"Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination"|comment:mint	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:ff1+buOox6sBrw3AMb7jytEJPDk10090	intact-crc:ECCF9DF1C9216F1A|rigid:ofXpZBaLTf3etEP/5+mJ/gQJuSU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P70232	uniprotkb:P18052	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703205|mint:MINT-6439931|imex:IM-11535-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439933(identity)	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2|mint:MINT-6439937(identity)	-	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	-	figure legend:f6b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	intact-crc:18C04225A08BA148|rigid:fXbryVtu8ReO5I6sQGhKPMAD++A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P70232	uniprotkb:Q9JMB8	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-7703151|ensembl:ENSMUSP00000086623|ensembl:ENSMUSP00000124025|intact:MINT-6439843|uniprotkb:Q8C6X1	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:cntn6_mouse(display_long)|uniprotkb:Cntn6(gene name)|psi-mi:Cntn6(display_short)|uniprotkb:Neural recognition molecule NB-3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703565|mint:MINT-6439892|imex:IM-11535-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439894(identity)	ensembl:ENSMUSG00000030092(gene)|ensembl:ENSMUST00000089215(transcript)|ensembl:ENSMUST00000162872(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR036116|interpro:IPR036179|mint:Q9JMB8|rcsb pdb:5E55|rcsb pdb:5E5U|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_017177167.1|refseq:XP_017177168.1|refseq:NP_059079.2|refseq:XP_006506444.1|refseq:XP_006506445.1|refseq:XP_006506446.1|refseq:XP_006506447.1|mint:MINT-6439898(identity)	-	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	function:"Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination"|comment:mint	figure legend:f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:ff1+buOox6sBrw3AMb7jytEJPDk10090	intact-crc:73AC9543DDC9831D|rigid:ofXpZBaLTf3etEP/5+mJ/gQJuSU	false	ha tag:?-?(MINT-6439895)	myc tag:?-?(MINT-6439899)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9JMB8	uniprotkb:P70232	intact:EBI-7703151|ensembl:ENSMUSP00000086623|ensembl:ENSMUSP00000124025|intact:MINT-6439843|uniprotkb:Q8C6X1	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	psi-mi:cntn6_mouse(display_long)|uniprotkb:Cntn6(gene name)|psi-mi:Cntn6(display_short)|uniprotkb:Neural recognition molecule NB-3(gene name synonym)	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703518|mint:MINT-6439879|imex:IM-11535-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000030092(gene)|ensembl:ENSMUST00000089215(transcript)|ensembl:ENSMUST00000162872(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR036116|interpro:IPR036179|mint:Q9JMB8|rcsb pdb:5E55|rcsb pdb:5E5U|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_017177167.1|refseq:XP_017177168.1|refseq:NP_059079.2|refseq:XP_006506444.1|refseq:XP_006506445.1|refseq:XP_006506446.1|refseq:XP_006506447.1|mint:MINT-6439881(identity)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439883(identity)	-	function:"Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination"|comment:mint	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	figure legend:f1b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/03/04	2014/10/16	rogid:ff1+buOox6sBrw3AMb7jytEJPDk10090	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	intact-crc:4ED62C3BA3562C78|rigid:ofXpZBaLTf3etEP/5+mJ/gQJuSU	false	myc tag:?-?(MINT-6439889)	ha tag:?-?(MINT-6439886)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70232	uniprotkb:P18052	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703598|mint:MINT-6439905|imex:IM-11535-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439911(identity)	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2|mint:MINT-6439907(identity)	-	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	-	figure legend:f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	intact-crc:27FAF34C31DC7D25|rigid:fXbryVtu8ReO5I6sQGhKPMAD++A	false	ha tag:?-?(MINT-6439912)	tag:?-?(MINT-6439908)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70232	uniprotkb:P18052	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703650|mint:MINT-6439918|imex:IM-11535-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439924(identity)	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2|mint:MINT-6439920(identity)	-	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	-	figure legend:f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	intact-crc:1CE46541DA262F0E|rigid:fXbryVtu8ReO5I6sQGhKPMAD++A	false	ha tag:?-?(MINT-6439925)	tag:?-?(MINT-6439921)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P70232	uniprotkb:P18052	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-6597520|ensembl:ENSMUSP00000076533|uniprotkb:A2AHF2|uniprotkb:Q61808	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:ptpra_mouse(display_long)|uniprotkb:Ptpra(gene name)|psi-mi:Ptpra(display_short)|uniprotkb:Lrp(gene name synonym)|uniprotkb:Ptpa(gene name synonym)|uniprotkb:LCA-related phosphatase(gene name synonym)|uniprotkb:PTPTY-28(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703753|mint:MINT-6439945|imex:IM-11535-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439949(identity)	ensembl:ENSMUSG00000027303(gene)|ensembl:ENSMUST00000077303(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|rcsb pdb:1P15|rcsb pdb:1YFO|reactome:R-MMU-375165|reactome:R-MMU-5673001|mint:P18052|refseq:NP_033006.2|mint:MINT-6439947(identity)	go:"GO:0009986"(cell surface)	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	-	figure legend:f6c|comment:Upon CHL1 activation.|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-cerebral_cortical_neuron)|taxid:10090(Mouse cerebral cortical neuron)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:2OLnRSJvcMrmaAF1Jw9t/tpt/L410090	intact-crc:E2AD942DA9DDA5FD|rigid:fXbryVtu8ReO5I6sQGhKPMAD++A	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9JMB8	uniprotkb:P70232	intact:EBI-7703151|ensembl:ENSMUSP00000086623|ensembl:ENSMUSP00000124025|intact:MINT-6439843|uniprotkb:Q8C6X1	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	psi-mi:cntn6_mouse(display_long)|uniprotkb:Cntn6(gene name)|psi-mi:Cntn6(display_short)|uniprotkb:Neural recognition molecule NB-3(gene name synonym)	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703791|mint:MINT-6439957|imex:IM-11535-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000030092(gene)|ensembl:ENSMUST00000089215(transcript)|ensembl:ENSMUST00000162872(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR036116|interpro:IPR036179|mint:Q9JMB8|rcsb pdb:5E55|rcsb pdb:5E5U|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_017177167.1|refseq:XP_017177168.1|refseq:NP_059079.2|refseq:XP_006506444.1|refseq:XP_006506445.1|refseq:XP_006506446.1|refseq:XP_006506447.1|mint:MINT-6439960(identity)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439962(identity)	go:"GO:0043005"(neuron projection)	function:"Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination"|comment:mint	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	figure legend:f1e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-cerebral_cortical_neuron)|taxid:10090(Mouse cerebral cortical neuron)	-	2008/03/04	2014/10/16	rogid:ff1+buOox6sBrw3AMb7jytEJPDk10090	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	intact-crc:363857572CF5C275|rigid:ofXpZBaLTf3etEP/5+mJ/gQJuSU	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P70232	uniprotkb:Q9JMB8	intact:EBI-7703109|ensembl:ENSMUSP00000063933|ensembl:ENSMUSP00000144758|uniprotkb:Q8C823|uniprotkb:Q8BS24|uniprotkb:A2RRK1|intact:MINT-4106227|uniprotkb:Q8C6W0|uniprotkb:Q8VBY7	intact:EBI-7703151|ensembl:ENSMUSP00000086623|ensembl:ENSMUSP00000124025|intact:MINT-6439843|uniprotkb:Q8C6X1	psi-mi:nchl1_mouse(display_long)|uniprotkb:Chl1(gene name)|psi-mi:Chl1(display_short)|uniprotkb:Call(gene name synonym)|uniprotkb:Cell adhesion molecule with homology to L1CAM(gene name synonym)|uniprotkb:Close homolog of L1(gene name synonym)|uniprotkb:Chl1-like protein(gene name synonym)	psi-mi:cntn6_mouse(display_long)|uniprotkb:Cntn6(gene name)|psi-mi:Cntn6(display_short)|uniprotkb:Neural recognition molecule NB-3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Ye et al. (2008)	pubmed:18046458|imex:IM-11535|mint:MINT-6439826	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7703832|mint:MINT-6439979|imex:IM-11535-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P70232|interpro:IPR003598(Immunoglobulin subtype 2)|refseq:XP_017176864.1|refseq:XP_017176865.1|ensembl:ENSMUSG00000030077(gene)|ensembl:ENSMUST00000066905(transcript)|ensembl:ENSMUST00000203830(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002020"(protease binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0035640"(exploration behavior)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050890"(cognition)|refseq:NP_031723.2|refseq:XP_006505535.1|mint:MINT-6439982(identity)	ensembl:ENSMUSG00000030092(gene)|ensembl:ENSMUST00000089215(transcript)|ensembl:ENSMUST00000162872(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0030424"(axon)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR036116|interpro:IPR036179|mint:Q9JMB8|rcsb pdb:5E55|rcsb pdb:5E5U|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_017177167.1|refseq:XP_017177168.1|refseq:NP_059079.2|refseq:XP_006506444.1|refseq:XP_006506445.1|refseq:XP_006506446.1|refseq:XP_006506447.1|mint:MINT-6439984(identity)	go:"GO:0009986"(cell surface)	comment:mint|function:Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane	function:"Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination"|comment:mint	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2008/03/04	2014/10/16	rogid:aA/C3w3sLouQMDeMPF7F9LiDYZY10090	rogid:ff1+buOox6sBrw3AMb7jytEJPDk10090	intact-crc:04CE786AD039ED76|rigid:ofXpZBaLTf3etEP/5+mJ/gQJuSU	false	ha tag:?-?(MINT-6439993)	myc tag:?-?(MINT-6439990)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)