#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01831 uniprotkb:P13288 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 intact:EBI-1630636|uniprotkb:Q777D1 psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0018"(two hybrid) Lu et al. (2007) pubmed:18024891 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1630645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 - - - figure legend:1 A taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/29 2014/10/16 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 intact-crc:E138C67AE5470528|rigid:3N9497lgAx854LhKkfNsfnV9QRg false sufficient binding region:509-835 biological feature:300-300 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01831 uniprotkb:P13288 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 intact:EBI-1630636|uniprotkb:Q777D1 psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0018"(two hybrid) Lu et al. (2007) pubmed:18024891 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1631909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/01/29 2014/10/16 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 intact-crc:F4086BCC9153C8FD|rigid:3N9497lgAx854LhKkfNsfnV9QRg false sufficient binding region:509-835 biological feature:300-300|sufficient binding region:1-293|sufficient binding region:1-429 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01831 uniprotkb:P13288 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 intact:EBI-1630636|uniprotkb:Q777D1 psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lu et al. (2007) pubmed:18024891 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1632296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 - - - figure legend:1 B|delivery method:Q01831; Q777D1 transfection taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/01/29 2014/10/16 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 intact-crc:371E95EF1690750F|rigid:3N9497lgAx854LhKkfNsfnV9QRg false ha tag:?-?|sufficient binding region:509-835 biological feature:102-102 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P13288 uniprotkb:Q01831 intact:EBI-1630636|uniprotkb:Q777D1 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lu et al. (2007) pubmed:18024891 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1632308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N - - - figure legend:1 B|delivery method:Q01831; Q777D1 transfection taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/01/29 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 intact-crc:8F2F8A062B1F8D66|rigid:3N9497lgAx854LhKkfNsfnV9QRg false biological feature:102-102 ha tag:?-?|sufficient binding region:509-835 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13288 uniprotkb:Q01831 intact:EBI-1630636|uniprotkb:Q777D1 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lu et al. (2007) pubmed:18024891 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1632336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N - - - figure legend:1 C|delivery method:Q01831; Q777D1 transfection taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/01/29 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 intact-crc:5670317FBD43F4FF|rigid:3N9497lgAx854LhKkfNsfnV9QRg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13288 uniprotkb:Q01831 intact:EBI-1630636|uniprotkb:Q777D1 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:"MI:0096"(pull down) Lu et al. (2007) pubmed:18024891 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1632350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N - - - figure legend:1 D taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/01/29 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 intact-crc:76087B95A4A3D626|rigid:3N9497lgAx854LhKkfNsfnV9QRg false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q01831 uniprotkb:P13288 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 intact:EBI-1630636|uniprotkb:Q777D1 psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Lu et al. (2007) pubmed:18024891 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1632369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 go:"GO:0005634"(nucleus) - - figure legend:2 A|delivery method:Q01831; Q777D1 transfection taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2008/01/29 2014/10/16 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 intact-crc:DF6B5BF4E5AF3B5F|rigid:3N9497lgAx854LhKkfNsfnV9QRg false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P13288 uniprotkb:Q01831 intact:EBI-1630636|uniprotkb:Q777D1 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Lu et al. (2007) pubmed:18024891 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1632388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N go:"GO:0005634"(nucleus) - - figure legend:2 C|comment:XPC partially colocalized with BGLF4 in the nuclei of NA cells 24 h post-induction of lytic DNA replication.|agonist:Expression of EBV immediate-early transactivator, Rta, is an agonist of this interaction.|delivery method:Q01831 transfection taxid:9606(human-na)|taxid:9606(Homo sapiens NA cell line derived from patient with squamous cell carcinoma of the tongue) - 2008/01/29 2014/10/16 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 intact-crc:195D2D57B5BFFA0D|rigid:3N9497lgAx854LhKkfNsfnV9QRg false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q01831 uniprotkb:P13288 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 intact:EBI-1630636|uniprotkb:Q777D1 psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:kr2_ebvb9(display_long)|uniprotkb:BGLF4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lu et al. (2007) pubmed:18024891 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1632406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044199"(host cell nuclear envelope)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:YP_401688.1 - - - figure legend:3|comment:This result indicates that BGLF4 interacts specifically with XPC in NA cells undergoing lytic DNA replication.|delivery method:Q777D1; Q01831 transfection|agonist:Expression of EBV immediate-early transactivator, Rta, is an agonist of this interaction. taxid:9606(human-na)|taxid:9606(Homo sapiens NA cell line derived from patient with squamous cell carcinoma of the tongue) - 2008/01/29 2014/10/16 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rogid:Hmx17O/ypVbRvMs4w+gkgRjPvRg10377 intact-crc:6D3C5A5B14F9568B|rigid:3N9497lgAx854LhKkfNsfnV9QRg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)