#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P19883-2	uniprotkb:P03950	intact:EBI-1571208|ensembl:ENSP00000380151	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:p19883-2(display_long)|uniprotkb:FST(gene name)|psi-mi:FST(display_short)|uniprotkb:Activin-binding protein(gene name synonym)|uniprotkb:FS288(isoform synonym)|uniprotkb:FS-288(isoform synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gao et al. (2007)	pubmed:17991437|imex:IM-19783	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571220|imex:IM-19783-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1571188(isoform-parent)|ensembl:ENSG00000134363(gene)|ensembl:ENST00000396947(transcript)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	author-identifiers:PREY gene NM_006350|figure legend:Fig. 4 A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/04	2014/10/16	rogid:OCOMgZgjjbuP2jNVwcJEKC7BfhA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	intact-crc:50FCDA2733E93E77|rigid:DyfNv4wZYuoYSvbZzx2RfM7KUZ4	false	sufficient binding region:166-317	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19883-2	uniprotkb:P03950	intact:EBI-1571208|ensembl:ENSP00000380151	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	psi-mi:p19883-2(display_long)|uniprotkb:FST(gene name)|psi-mi:FST(display_short)|uniprotkb:Activin-binding protein(gene name synonym)|uniprotkb:FS288(isoform synonym)|uniprotkb:FS-288(isoform synonym)	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gao et al. (2007)	pubmed:17991437|imex:IM-19783	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571228|imex:IM-19783-2	author score:PREY gene NM_006350	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1571188(isoform-parent)|ensembl:ENSG00000134363(gene)|ensembl:ENST00000396947(transcript)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	-	-	-	figure legend:Fig. 1 A, 4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/01/04	2014/10/16	rogid:OCOMgZgjjbuP2jNVwcJEKC7BfhA9606	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	intact-crc:E52614C7389418A0|rigid:DyfNv4wZYuoYSvbZzx2RfM7KUZ4	false	sufficient binding region:166-317	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03950	uniprotkb:P19883	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-1571188|uniprotkb:Q9BTH0|ensembl:ENSP00000256759|uniprotkb:B5BU94	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:fst_human(display_long)|uniprotkb:Activin-binding protein(gene name synonym)|uniprotkb:FST(gene name)|psi-mi:FST(display_short)	psi-mi:"MI:0096"(pull down)	Gao et al. (2007)	pubmed:17991437|imex:IM-19783	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571245|imex:IM-19783-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	ensembl:ENSG00000134363(gene)|ensembl:ENST00000256759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007389"(pattern specification process)|go:"GO:0008585"(female gonad development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0038102"(activin receptor antagonist activity)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048185"(activin binding)|go:"GO:0051798"(positive regulation of hair follicle development)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR015369(Follistatin)|interpro:IPR017878|interpro:IPR036058|interpro:IPR036773|rcsb pdb:2P6A|rcsb pdb:3HH2|rcsb pdb:5JHW|reactome:R-HSA-2473224|rcsb pdb:2B0U|refseq:NP_006341.1|refseq:NP_037541.1	-	-	-	figure legend:1 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/01/04	2014/10/16	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:+g4SG1U00WzrjZWzOXPDoMP5c/I9606	intact-crc:4908FF300BAA42BC|rigid:G00ejarYfjo0BPA4h6jOYZMCPj8	false	-	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03950	uniprotkb:P19883	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-1571188|uniprotkb:Q9BTH0|ensembl:ENSP00000256759|uniprotkb:B5BU94	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:fst_human(display_long)|uniprotkb:Activin-binding protein(gene name synonym)|uniprotkb:FST(gene name)|psi-mi:FST(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Gao et al. (2007)	pubmed:17991437|imex:IM-19783	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571259|imex:IM-19783-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	ensembl:ENSG00000134363(gene)|ensembl:ENST00000256759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007389"(pattern specification process)|go:"GO:0008585"(female gonad development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0038102"(activin receptor antagonist activity)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048185"(activin binding)|go:"GO:0051798"(positive regulation of hair follicle development)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR015369(Follistatin)|interpro:IPR017878|interpro:IPR036058|interpro:IPR036773|rcsb pdb:2P6A|rcsb pdb:3HH2|rcsb pdb:5JHW|reactome:R-HSA-2473224|rcsb pdb:2B0U|refseq:NP_006341.1|refseq:NP_037541.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 2 C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/01/04	2014/10/16	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:+g4SG1U00WzrjZWzOXPDoMP5c/I9606	intact-crc:A14285128C51A539|rigid:G00ejarYfjo0BPA4h6jOYZMCPj8	false	yellow fluorescent protein tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P03950	uniprotkb:P19883	intact:EBI-525291|uniprotkb:Q8WXE7|uniprotkb:Q05CV1|uniprotkb:Q53X86|uniprotkb:Q6P5T2|ensembl:ENSP00000336762|ensembl:ENSP00000381077	intact:EBI-1571188|uniprotkb:Q9BTH0|ensembl:ENSP00000256759|uniprotkb:B5BU94	psi-mi:angi_human(display_long)|uniprotkb:Ribonuclease 5(gene name synonym)|uniprotkb:ANG(gene name)|psi-mi:ANG(display_short)|uniprotkb:RNASE5(gene name synonym)	psi-mi:fst_human(display_long)|uniprotkb:Activin-binding protein(gene name synonym)|uniprotkb:FST(gene name)|psi-mi:FST(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Gao et al. (2007)	pubmed:17991437|imex:IM-19783	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571302|imex:IM-19783-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001091046.1|refseq:NP_001136.1|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019843"(rRNA binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0032431"(activation of phospholipase A2 activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR001427(Pancreatic ribonuclease)|interpro:IPR023411|interpro:IPR023412|interpro:IPR036816|rcsb pdb:1A4Y|rcsb pdb:1ANG|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016477"(cell migration)|rcsb pdb:1AWZ|rcsb pdb:1B1E|rcsb pdb:1B1I|rcsb pdb:1B1J|rcsb pdb:1GV7|rcsb pdb:1H0D|rcsb pdb:1H52|rcsb pdb:1H53|rcsb pdb:1HBY|rcsb pdb:1K58|rcsb pdb:1K59|rcsb pdb:1K5A|rcsb pdb:1K5B|rcsb pdb:1UN3|rcsb pdb:1UN4|rcsb pdb:1UN5|rcsb pdb:2ANG|rcsb pdb:4AHD|rcsb pdb:4AHE|rcsb pdb:4AHF|rcsb pdb:4AHG|rcsb pdb:4AHH|rcsb pdb:4AHI|rcsb pdb:4AHJ|rcsb pdb:4AHK|rcsb pdb:4AHL|rcsb pdb:4AHM|rcsb pdb:4AHN|rcsb pdb:4AOH|rcsb pdb:4B36|rcsb pdb:5EOP|rcsb pdb:5EPZ|rcsb pdb:5EQO|rcsb pdb:5M9A|rcsb pdb:5M9C|rcsb pdb:5M9G|rcsb pdb:5M9J|rcsb pdb:5M9M|rcsb pdb:5M9P|rcsb pdb:5M9Q|rcsb pdb:5M9R|rcsb pdb:5M9S|rcsb pdb:5M9T|rcsb pdb:5M9V|reactome:R-HSA-418990|reactome:R-HSA-9708296|ensembl:ENSG00000214274(gene)|ensembl:ENST00000336811(transcript)|ensembl:ENST00000397990(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001878"(response to yeast)|go:"GO:0001890"(placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006651"(diacylglycerol biosynthetic process)|go:"GO:0007154"(cell communication)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008201"(heparin binding)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009725"(response to hormone)|go:"GO:0015629"(actin cytoskeleton)	ensembl:ENSG00000134363(gene)|ensembl:ENST00000256759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007389"(pattern specification process)|go:"GO:0008585"(female gonad development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0038102"(activin receptor antagonist activity)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048185"(activin binding)|go:"GO:0051798"(positive regulation of hair follicle development)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR015369(Follistatin)|interpro:IPR017878|interpro:IPR036058|interpro:IPR036773|rcsb pdb:2P6A|rcsb pdb:3HH2|rcsb pdb:5JHW|reactome:R-HSA-2473224|rcsb pdb:2B0U|refseq:NP_006341.1|refseq:NP_037541.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 3|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/01/04	2014/10/16	rogid:CSOTublnrV3DIGJfeyCfT14p8m89606	rogid:+g4SG1U00WzrjZWzOXPDoMP5c/I9606	intact-crc:8FE50429F0580EFC|rigid:G00ejarYfjo0BPA4h6jOYZMCPj8	false	yellow fluorescent protein tag:?-?	cyan fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)