#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O57209 uniprotkb:O57215 intact:EBI-7685240|intact:MINT-6178060 intact:EBI-7685221|intact:MINT-6178046 psi-mi:mcel_vacca(display_long)|uniprotkb:mRNA-capping enzyme large subunit(gene name synonym)|uniprotkb:Virus termination factor large subunit(gene name synonym)|uniprotkb:mRNA-capping enzyme 97 kDa subunit(gene name synonym)|uniprotkb:mRNA-capping enzyme D1 subunit(gene name synonym)|uniprotkb:ACAM3000_MVA_098(locus name)|uniprotkb:MVA098R(locus name) psi-mi:mces_vacca(display_long)|uniprotkb:Virus termination factor small subunit(gene name synonym)|uniprotkb:mRNA-capping enzyme 33 kDa subunit(gene name synonym)|uniprotkb:mRNA-capping enzyme D12 subunit(gene name synonym)|uniprotkb:mRNA-capping enzyme small subunit(gene name synonym)|uniprotkb:ACAM3000_MVA_109(locus name)|uniprotkb:MVA109L(locus name) psi-mi:"MI:0114"(x-ray crystallography) De et al. (2007) pubmed:17989694|imex:IM-11511|mint:MINT-6178037 taxid:126794(vacv)|taxid:126794("Vaccinia virus (strain Ankara)") taxid:126794(vacv)|taxid:126794("Vaccinia virus (strain Ankara)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7685213|mint:MINT-6178056|imex:IM-11511-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004484"(mRNA guanylyltransferase activity)|go:"GO:0004651"(polynucleotide 5'-phosphatase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0046872"(metal ion binding)|mint:O57209|interpro:IPR004971(mRNA capping enzyme, large subunit)|interpro:IPR019602|interpro:IPR029063|interpro:IPR039753|mint:MINT-6178069(identity) go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0006353"(DNA-templated transcription, termination)|mint:O57215|interpro:IPR005009(Poxvirus mRNA capping enzyme, small subunit)|interpro:IPR043096|mint:MINT-6178058(identity) - function:Catalyzes the first two reactions in the mRNA cap formation pathway|comment:mint function:Catalyzes the last reaction in the mRNA cap formation pathway|comment:mint figure legend:f1|comment:"The authors report the crystal structure(2.7 Å resolution)of the heterodimer of the N7-MT domain of vaccinia virus D1 with bound S-adenosyl-homocysteine (AdoHcy) in complex with its stimulatory D12 subunit."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/12 2014/10/16 rogid:kYFHN8AUuUaeHp5naYBVV1Bhsaw126794 rogid:sT6OdPeCGDpdpLqP6CaD4D74krM126794 intact-crc:74D6C5D8583496B0|rigid:skUSy8GTyrOpXPeyJ2Ch1wnZ/MI false binding-associated region:545-844(MINT-6178072) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)