#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41235 uniprotkb:Q99967 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 intact:EBI-937732|uniprotkb:O95426|uniprotkb:Q5VTF4|ensembl:ENSP00000356623|ensembl:ENSP00000442831 psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:cite2_human(display_long)|uniprotkb:CITED2(gene name)|psi-mi:CITED2(display_short)|uniprotkb:MRG1(gene name synonym)|uniprotkb:MSG-related protein 1(gene name synonym)|uniprotkb:P35srj(gene name synonym) psi-mi:"MI:0096"(pull down) Qu et al. (2007) pubmed:17932483|imex:IM-14051|mint:MINT-6175305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7635916|mint:MINT-6175313|imex:IM-14051-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N|mint:MINT-6175316(identity) refseq:NP_001161860.1|refseq:NP_006070.2|refseq:NP_001161861.2|ensembl:ENSG00000164442(gene)|ensembl:ENST00000367651(transcript)|ensembl:ENST00000536159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003156"(regulation of animal organ formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007530"(sex determination)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035802"(adrenal cortex formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046697"(decidualization)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:1900164"(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR007576(CITED)|mint:Q99967|rcsb pdb:1P4Q|rcsb pdb:1R8U|reactome:R-HSA-1234158|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-9614657|go:"GO:0010629"(negative regulation of gene expression)|mint:MINT-6175315(identity) - - - figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/02/07 2014/10/16 rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 rogid:+PWkzMA5AdgqCJHJOP/tT7tjU8w9606 intact-crc:60E7B66E71A4DC43|rigid:sb2jjOiY/6avNGqoIiVaFKu29ms false myc tag:?-?(MINT-6175317) glutathione s tranferase tag:?-?(MINT-6175321) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99967 uniprotkb:P41235 intact:EBI-937732|uniprotkb:O95426|uniprotkb:Q5VTF4|ensembl:ENSP00000356623|ensembl:ENSP00000442831 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 psi-mi:cite2_human(display_long)|uniprotkb:CITED2(gene name)|psi-mi:CITED2(display_short)|uniprotkb:MRG1(gene name synonym)|uniprotkb:MSG-related protein 1(gene name synonym)|uniprotkb:P35srj(gene name synonym) psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:"MI:0018"(two hybrid) Qu et al. (2007) pubmed:17932483|imex:IM-14051|mint:MINT-6175305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7635982|mint:MINT-6175330|imex:IM-14051-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161860.1|refseq:NP_006070.2|refseq:NP_001161861.2|ensembl:ENSG00000164442(gene)|ensembl:ENST00000367651(transcript)|ensembl:ENST00000536159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003156"(regulation of animal organ formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007530"(sex determination)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035802"(adrenal cortex formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046697"(decidualization)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:1900164"(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR007576(CITED)|mint:Q99967|rcsb pdb:1P4Q|rcsb pdb:1R8U|reactome:R-HSA-1234158|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-9614657|go:"GO:0010629"(negative regulation of gene expression)|mint:MINT-6175332(identity) refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N|mint:MINT-6175336(identity) - - - figure legend:F6b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/07 2014/10/16 rogid:+PWkzMA5AdgqCJHJOP/tT7tjU8w9606 rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 intact-crc:07CACBAD9478ECFB|rigid:sb2jjOiY/6avNGqoIiVaFKu29ms false tag:?-?(MINT-6175333)|binding-associated region:124-270(MINT-6175343) tag:?-?(MINT-6175337) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41235 uniprotkb:Q99967 intact:EBI-1049011|uniprotkb:Q92654|uniprotkb:Q92655|uniprotkb:Q99864|uniprotkb:Q9NQH0|uniprotkb:O00659|uniprotkb:O00723|uniprotkb:Q14540|uniprotkb:Q5QPB8|uniprotkb:Q6B4V5|uniprotkb:Q6B4V6|uniprotkb:Q6B4V7|uniprotkb:Q92653|uniprotkb:A5JW41|uniprotkb:B2RPP8|ensembl:ENSP00000312987 intact:EBI-937732|uniprotkb:O95426|uniprotkb:Q5VTF4|ensembl:ENSP00000356623|ensembl:ENSP00000442831 psi-mi:hnf4a_human(display_long)|uniprotkb:Transcription factor HNF-4(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym)|uniprotkb:Transcription factor 14(gene name synonym)|uniprotkb:HNF4A(gene name)|psi-mi:HNF4A(display_short)|uniprotkb:HNF4(gene name synonym)|uniprotkb:NR2A1(gene name synonym)|uniprotkb:TCF14(gene name synonym) psi-mi:cite2_human(display_long)|uniprotkb:CITED2(gene name)|psi-mi:CITED2(display_short)|uniprotkb:MRG1(gene name synonym)|uniprotkb:MSG-related protein 1(gene name synonym)|uniprotkb:P35srj(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Qu et al. (2007) pubmed:17932483|imex:IM-14051|mint:MINT-6175305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7636014|mint:MINT-6175350|imex:IM-14051-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000448.3|refseq:NP_001025174.1|refseq:NP_001025175.1|refseq:NP_787110.2|refseq:NP_849181.1|refseq:NP_001274111.1|refseq:NP_001274112.1|refseq:NP_001274113.1|refseq:NP_001245284.1|ensembl:ENSG00000101076(gene)|ensembl:ENST00000316099(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060398"(regulation of growth hormone receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR039067|mint:P41235|rcsb pdb:1PZL|rcsb pdb:3CBB|rcsb pdb:3FS1|rcsb pdb:4B7W|rcsb pdb:4IQR|rcsb pdb:6CHT|reactome:R-HSA-210745|reactome:R-HSA-383280|dip:DIP-499N|mint:MINT-6175352(identity) refseq:NP_001161860.1|refseq:NP_006070.2|refseq:NP_001161861.2|ensembl:ENSG00000164442(gene)|ensembl:ENST00000367651(transcript)|ensembl:ENST00000536159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003156"(regulation of animal organ formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007530"(sex determination)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035802"(adrenal cortex formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046697"(decidualization)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050693"(LBD domain binding)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:1900164"(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR007576(CITED)|mint:Q99967|rcsb pdb:1P4Q|rcsb pdb:1R8U|reactome:R-HSA-1234158|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-9614657|go:"GO:0010629"(negative regulation of gene expression)|mint:MINT-6175356(identity) go:"GO:0005634"(nucleus) - - figure legend:SF4|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/02/07 2014/10/16 rogid:lul0rM/fHNAVsH3ZizbMOXPPL0k9606 rogid:+PWkzMA5AdgqCJHJOP/tT7tjU8w9606 intact-crc:54CECE15E913DD4E|rigid:sb2jjOiY/6avNGqoIiVaFKu29ms false myc tag:?-?(MINT-6175353) green fluorescent protein tag:?-?(MINT-6175357) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0396"(predetermined participant)