#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16706	uniprotkb:Q10045	intact:EBI-7601642|uniprotkb:Q16767|intact:MINT-2807655|ensembl:ENSP00000261483	intact:EBI-7601682|intact:UNK-5887201|ensemblmetazoa:T07A5.2.1	psi-mi:ma2a1_human(display_long)|uniprotkb:MAN2A1(gene name)|psi-mi:MAN2A1(display_short)|uniprotkb:MANA2(gene name synonym)|uniprotkb:Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase(gene name synonym)|uniprotkb:Golgi alpha-mannosidase II(gene name synonym)|uniprotkb:Mannosidase alpha class 2A member 1(gene name synonym)	psi-mi:unc50_caeel(display_long)|uniprotkb:unc-50(gene name)|psi-mi:unc-50(display_short)|uniprotkb:T07A5.2(orf name)|uniprotkb:Uncoordinated protein 50(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Eimer et al. (2007)	pubmed:17853888|imex:IM-10768|mint:MINT-6167083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7601635|mint:MINT-6167093|imex:IM-10768-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002363.2|ensembl:ENSG00000112893(gene)|ensembl:ENST00000261483(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0004559"(alpha-mannosidase activity)|go:"GO:0004572"(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016799"(hydrolase activity, hydrolyzing N-glycosyl compounds)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR027291|interpro:IPR028995|interpro:IPR037094|mint:Q16706|reactome:R-HSA-6811438|reactome:R-HSA-9694548|reactome:R-HSA-975578|mint:MINT-6167096(identity)	mint:Q10045|wormbase:T07A5.2|refseq:NP_499279.2|interpro:IPR007881(UNC-50)|ensemblmetazoa:WBGene00006785(gene)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0015031"(protein transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0097120"(receptor localization to synapse)|ensemblmetazoa:T07A5.2.1(transcript)|mint:MINT-6167095(identity)	go:"GO:0005794"(Golgi apparatus)	comment:mint|function:Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway	comment:mint|function:Required for cell surface expression of acetylcholine receptors in body-wall muscles	figure legend:F7C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-body muscle)|taxid:6239(Caenorhabditis elegans body muscle)	-	2008/01/10	2014/10/16	rogid:ied16ghThYS9/MgF9m9XxYyZ3w49606	rogid:Zg+ECvCmdDuwX3AGa40jUnpb1+o6239	intact-crc:2AF31B50EDB5DF7B|rigid:JDC3rktTM9C8n+tuvRmk6dE2ZFg	false	green fluorescent protein tag:?-?(MINT-6167148)	tag:?-?(MINT-6167144)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P36125	uniprotkb:P47102	intact:EBI-26378|uniprotkb:D6VX95|ensemblfungi:YKR030W	intact:EBI-7539|uniprotkb:D6VWK4|ensemblfungi:YJR031C	psi-mi:gmh1_yeast(display_long)|uniprotkb:YKR030W(locus name)|uniprotkb:GEA1-6 membrane-associated high-copy suppressor protein 1(gene name synonym)|uniprotkb:GMH1(gene name)|psi-mi:GMH1(display_short)|uniprotkb:MSG1(gene name synonym)	psi-mi:gea1_yeast(display_long)|uniprotkb:J1580(orf name)|uniprotkb:YJR031C(locus name)|uniprotkb:GEA1(gene name)|psi-mi:GEA1(display_short)	psi-mi:"MI:0018"(two hybrid)	Eimer et al. (2007)	pubmed:17853888|imex:IM-10768|mint:MINT-6167083	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7601734|mint:MINT-6167101|imex:IM-10768-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012955.1|sgd:S000001738|mint:P36125|dip:DIP-2023N|ensemblfungi:YKR030W(gene)|ensemblfungi:YKR030W_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007881(UNC-50)|mint:MINT-6167104(identity)	refseq:NP_012565.1|sgd:S000003792|mint:P47102|dip:DIP-5697N|ensemblfungi:YJR031C(gene)|ensemblfungi:YJR031C_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005933"(cellular bud)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|rcsb pdb:1RE0|mint:MINT-6167103(identity)	-	-	-	figure legend:F8|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/01/10	2014/10/16	rogid:lmgeWk7CkMQRDAfkDOgwqC9rb/g559292	rogid:TjOE53hvXDYkI/ldVH5qHL6kaZs559292	intact-crc:D3881CC5080AE5E4|rigid:QLOVzN0ABj9+at0loWsi9IT6ngQ	false	tag:?-?(MINT-6167106)	binding-associated region:748-1408(MINT-6167113)|tag:?-?(MINT-6167110)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q53HI1	uniprotkb:P47102	intact:EBI-7601760|uniprotkb:Q5U5U2|intact:MINT-4877084|uniprotkb:Q53S98|intact:MINT-4892643|uniprotkb:D3DVH4|intact:MINT-4910790|uniprotkb:Q6X7B9|uniprotkb:Q53TD6|intact:MINT-3083921|uniprotkb:Q9Y4S6|intact:MINT-8163660|intact:MINT-6167138|intact:MINT-4876135|uniprotkb:Q9UQF4|ensembl:ENSP00000350409	intact:EBI-7539|uniprotkb:D6VWK4|ensemblfungi:YJR031C	psi-mi:unc50_human(display_long)|uniprotkb:UNCL(gene name synonym)|uniprotkb:UNC50(gene name)|psi-mi:UNC50(display_short)|uniprotkb:HSD23(orf name)|uniprotkb:HSD-23(orf name)|uniprotkb:Uncoordinated-like protein(gene name synonym)|uniprotkb:Periodontal ligament-specific protein 22(gene name synonym)|uniprotkb:Protein GMH1 homolog(gene name synonym)	psi-mi:gea1_yeast(display_long)|uniprotkb:J1580(orf name)|uniprotkb:YJR031C(locus name)|uniprotkb:GEA1(gene name)|psi-mi:GEA1(display_short)	psi-mi:"MI:0018"(two hybrid)	Eimer et al. (2007)	pubmed:17853888|imex:IM-10768|mint:MINT-6167083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7601754|mint:MINT-6167116|imex:IM-10768-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054763.2|ensembl:ENSG00000115446(gene)|ensembl:ENST00000357765(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0034394"(protein localization to cell surface)|interpro:IPR007881(UNC-50)|mint:Q53HI1|mint:MINT-6167123(identity)	refseq:NP_012565.1|sgd:S000003792|mint:P47102|dip:DIP-5697N|ensemblfungi:YJR031C(gene)|ensemblfungi:YJR031C_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005933"(cellular bud)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|rcsb pdb:1RE0|mint:MINT-6167118(identity)	-	function:May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA|comment:mint	-	figure legend:F8|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/01/10	2014/10/16	rogid:SEM9kxgM745h3ObIz/L10d/YBWE9606	rogid:TjOE53hvXDYkI/ldVH5qHL6kaZs559292	intact-crc:B3BDCAB7DCC81699|rigid:KTlLZBzu+0v+9kLy55vpYDnyxPA	false	tag:?-?(MINT-6167124)	tag:?-?(MINT-6167121)|binding-associated region:748-1408(MINT-6167119)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q10045	uniprotkb:P47102	intact:EBI-7601682|intact:UNK-5887201|ensemblmetazoa:T07A5.2.1	intact:EBI-7539|uniprotkb:D6VWK4|ensemblfungi:YJR031C	psi-mi:unc50_caeel(display_long)|uniprotkb:unc-50(gene name)|psi-mi:unc-50(display_short)|uniprotkb:T07A5.2(orf name)|uniprotkb:Uncoordinated protein 50(gene name synonym)	psi-mi:gea1_yeast(display_long)|uniprotkb:J1580(orf name)|uniprotkb:YJR031C(locus name)|uniprotkb:GEA1(gene name)|psi-mi:GEA1(display_short)	psi-mi:"MI:0018"(two hybrid)	Eimer et al. (2007)	pubmed:17853888|imex:IM-10768|mint:MINT-6167083	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7601828|mint:MINT-6167126|imex:IM-10768-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q10045|wormbase:T07A5.2|refseq:NP_499279.2|interpro:IPR007881(UNC-50)|ensemblmetazoa:WBGene00006785(gene)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0015031"(protein transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0097120"(receptor localization to synapse)|ensemblmetazoa:T07A5.2.1(transcript)|mint:MINT-6167133(identity)	refseq:NP_012565.1|sgd:S000003792|mint:P47102|dip:DIP-5697N|ensemblfungi:YJR031C(gene)|ensemblfungi:YJR031C_mRNA(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005933"(cellular bud)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000904(SEC7-like)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|rcsb pdb:1RE0|mint:MINT-6167128(identity)	-	comment:mint|function:Required for cell surface expression of acetylcholine receptors in body-wall muscles	-	figure legend:F8|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2008/01/10	2014/10/16	rogid:Zg+ECvCmdDuwX3AGa40jUnpb1+o6239	rogid:TjOE53hvXDYkI/ldVH5qHL6kaZs559292	intact-crc:0E1ACF0225F3D301|rigid:Kl4DPat0ZxJrGW8qQMrBIfLdcCE	false	tag:?-?(MINT-6167134)	tag:?-?(MINT-6167129)|binding-associated region:748-1408(MINT-6167131)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)