#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7FRS8 uniprotkb:Q9LDI3 intact:EBI-2026616|uniprotkb:O82641|uniprotkb:Q2HIW7|uniprotkb:Q8GYR3|uniprotkb:Q8GZD7|ensemblplants:AT4G33000.1 intact:EBI-537551|uniprotkb:Q9LKR2|ensemblplants:AT5G35410.1 psi-mi:cnbla_arath(display_long)|uniprotkb:SOS3-like calcium binding protein 8(gene name synonym)|uniprotkb:F26P21_120(orf name)|uniprotkb:At4g33000(locus name)|uniprotkb:CBL10(gene name)|psi-mi:CBL10(display_short) psi-mi:cipko_arath(display_long)|uniprotkb:SNF1-related kinase 3.11(gene name synonym)|uniprotkb:Protein SALT OVERLY SENSITIVE 2(gene name synonym)|uniprotkb:CIPK24(gene name)|psi-mi:CIPK24(display_short)|uniprotkb:SnRK3.11(gene name synonym)|uniprotkb:SOS2(gene name synonym)|uniprotkb:At5g35410(locus name)|uniprotkb:F6I13.1(orf name)|uniprotkb:K21B8.3(orf name) psi-mi:"MI:0018"(two hybrid) Kim et al. (2007) pubmed:17825054|imex:IM-20153 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2026637|imex:IM-20153-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_195026.1|refseq:NP_849485.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|ensemblplants:AT4G33000(gene)|ensemblplants:AT4G33000.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0050801"(ion homeostasis) refseq:NP_198391.1|go:"GO:0009651"(response to salt stress)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR004041(NAF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018451|rcsb pdb:2EHB|rcsb pdb:4D28|go:"GO:0006468"(protein phosphorylation)|ensemblplants:AT5G35410(gene)|ensemblplants:AT5G35410.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-34745N - - - figure legend:Figure 5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/30 2014/10/16 rogid:MSTiLDXo1HYv3JPt4kFnlvlpjBY3702 rogid:RQgXuL8VS8nwPMEDigV1GP36hR43702 intact-crc:FD58E22F60EADB9C|rigid:vRAwjapIsRhl5bR0Dmn9j9oI8QM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7FRS8 uniprotkb:Q9LDI3 intact:EBI-2026616|uniprotkb:O82641|uniprotkb:Q2HIW7|uniprotkb:Q8GYR3|uniprotkb:Q8GZD7|ensemblplants:AT4G33000.1 intact:EBI-537551|uniprotkb:Q9LKR2|ensemblplants:AT5G35410.1 psi-mi:cnbla_arath(display_long)|uniprotkb:SOS3-like calcium binding protein 8(gene name synonym)|uniprotkb:F26P21_120(orf name)|uniprotkb:At4g33000(locus name)|uniprotkb:CBL10(gene name)|psi-mi:CBL10(display_short) psi-mi:cipko_arath(display_long)|uniprotkb:SNF1-related kinase 3.11(gene name synonym)|uniprotkb:Protein SALT OVERLY SENSITIVE 2(gene name synonym)|uniprotkb:CIPK24(gene name)|psi-mi:CIPK24(display_short)|uniprotkb:SnRK3.11(gene name synonym)|uniprotkb:SOS2(gene name synonym)|uniprotkb:At5g35410(locus name)|uniprotkb:F6I13.1(orf name)|uniprotkb:K21B8.3(orf name) psi-mi:"MI:0096"(pull down) Kim et al. (2007) pubmed:17825054|imex:IM-20153 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2026648|imex:IM-20153-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_195026.1|refseq:NP_849485.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|ensemblplants:AT4G33000(gene)|ensemblplants:AT4G33000.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0050801"(ion homeostasis) refseq:NP_198391.1|go:"GO:0009651"(response to salt stress)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR004041(NAF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018451|rcsb pdb:2EHB|rcsb pdb:4D28|go:"GO:0006468"(protein phosphorylation)|ensemblplants:AT5G35410(gene)|ensemblplants:AT5G35410.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-34745N - - - figure legend:Figure 5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/10/30 2014/10/16 rogid:MSTiLDXo1HYv3JPt4kFnlvlpjBY3702 rogid:RQgXuL8VS8nwPMEDigV1GP36hR43702 intact-crc:91E7C0408584D349|rigid:vRAwjapIsRhl5bR0Dmn9j9oI8QM false his tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9CB01 uniprotkb:Q7FRS8 intact:EBI-1572826|ensemblplants:AT3G54840.1|uniprotkb:A8MRL2|uniprotkb:Q9SV33 intact:EBI-2026616|uniprotkb:O82641|uniprotkb:Q2HIW7|uniprotkb:Q8GYR3|uniprotkb:Q8GZD7|ensemblplants:AT4G33000.1 psi-mi:rabf1_arath(display_long)|uniprotkb:RABF1(gene name)|psi-mi:RABF1(display_short)|uniprotkb:At3g54840(locus name)|uniprotkb:ARA-6(gene name synonym)|uniprotkb:RAB5C(gene name synonym)|uniprotkb:Ras-related protein Ara-6(gene name synonym)|uniprotkb:Ras-related protein Rab5C(gene name synonym)|uniprotkb:F28P10.180(orf name) psi-mi:cnbla_arath(display_long)|uniprotkb:SOS3-like calcium binding protein 8(gene name synonym)|uniprotkb:F26P21_120(orf name)|uniprotkb:At4g33000(locus name)|uniprotkb:CBL10(gene name)|psi-mi:CBL10(display_short) psi-mi:"MI:0663"(confocal microscopy) Kim et al. (2007) pubmed:17825054|imex:IM-20153 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2026681|imex:IM-20153-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT3G54840(gene)|ensemblplants:AT3G54840.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010009"(cytoplasmic side of endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045022"(early endosome to late endosome transport)|interpro:IPR027417|refseq:NP_001078287.1|refseq:NP_567008.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase) refseq:NP_195026.1|refseq:NP_849485.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|ensemblplants:AT4G33000(gene)|ensemblplants:AT4G33000.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0050801"(ion homeostasis) go:"GO:0005768"(endosome) - - figure legend:Figure 7c|comment:"The authors concluded \"this calcium sensor (CBL10) localizes to a population of endosomes that may include the PVC\" (pre-vacuolar compartments)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4100(nicbe)|taxid:4100(Nicotiana benthamiana) - 2008/10/30 2014/10/16 rogid:K6q9+eSED3ID5aOL22oY9DssUsY3702 rogid:MSTiLDXo1HYv3JPt4kFnlvlpjBY3702 intact-crc:3A9DFDF98606D881|rigid:nOHTeHc5H8lchgjEKIaJJ16sQgo false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9SN68 uniprotkb:Q7FRS8 intact:EBI-1606501|ensemblplants:AT4G19640.1 intact:EBI-2026616|uniprotkb:O82641|uniprotkb:Q2HIW7|uniprotkb:Q8GYR3|uniprotkb:Q8GZD7|ensemblplants:AT4G33000.1 psi-mi:raf2b_arath(display_long)|uniprotkb:RABF2B(gene name)|psi-mi:RABF2B(display_short)|uniprotkb:ARA-7(gene name synonym)|uniprotkb:RAB5B(gene name synonym)|uniprotkb:At4g19640(locus name)|uniprotkb:Ras-related protein Ara-7(gene name synonym)|uniprotkb:Ras-related protein Rab5B(gene name synonym)|uniprotkb:F24J7.190(orf name) psi-mi:cnbla_arath(display_long)|uniprotkb:SOS3-like calcium binding protein 8(gene name synonym)|uniprotkb:F26P21_120(orf name)|uniprotkb:At4g33000(locus name)|uniprotkb:CBL10(gene name)|psi-mi:CBL10(display_short) psi-mi:"MI:0663"(confocal microscopy) Kim et al. (2007) pubmed:17825054|imex:IM-20153 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2026693|imex:IM-20153-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4G01|refseq:NP_193699.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|rcsb pdb:2EFC|rcsb pdb:2EFD|rcsb pdb:2EFE|rcsb pdb:2EFH|interpro:IPR027417|ensemblplants:AT4G19640(gene)|ensemblplants:AT4G19640.1(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007033"(vacuole organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045324"(late endosome to vacuole transport) refseq:NP_195026.1|refseq:NP_849485.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|ensemblplants:AT4G33000(gene)|ensemblplants:AT4G33000.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0050801"(ion homeostasis) go:"GO:0005768"(endosome) - - figure legend:Figure 7f|comment:"The authors concluded \"this calcium sensor (CBL10) localizes to a population of endosomes that may include the PVC\" (pre-vacuolar compartments)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4100(nicbe)|taxid:4100(Nicotiana benthamiana) - 2008/10/30 2014/10/16 rogid:Qazjn9JOvICKAlfMKnOh+zYphQ03702 rogid:MSTiLDXo1HYv3JPt4kFnlvlpjBY3702 intact-crc:7E8579EC7646C337|rigid:tJxmumnIGEeIgmVsGr5nB6eWlr0 false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q7FRS8 uniprotkb:Q9LDI3 intact:EBI-2026616|uniprotkb:O82641|uniprotkb:Q2HIW7|uniprotkb:Q8GYR3|uniprotkb:Q8GZD7|ensemblplants:AT4G33000.1 intact:EBI-537551|uniprotkb:Q9LKR2|ensemblplants:AT5G35410.1 psi-mi:cnbla_arath(display_long)|uniprotkb:SOS3-like calcium binding protein 8(gene name synonym)|uniprotkb:F26P21_120(orf name)|uniprotkb:At4g33000(locus name)|uniprotkb:CBL10(gene name)|psi-mi:CBL10(display_short) psi-mi:cipko_arath(display_long)|uniprotkb:SNF1-related kinase 3.11(gene name synonym)|uniprotkb:Protein SALT OVERLY SENSITIVE 2(gene name synonym)|uniprotkb:CIPK24(gene name)|psi-mi:CIPK24(display_short)|uniprotkb:SnRK3.11(gene name synonym)|uniprotkb:SOS2(gene name synonym)|uniprotkb:At5g35410(locus name)|uniprotkb:F6I13.1(orf name)|uniprotkb:K21B8.3(orf name) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Kim et al. (2007) pubmed:17825054|imex:IM-20153 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2026711|imex:IM-20153-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_195026.1|refseq:NP_849485.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|ensemblplants:AT4G33000(gene)|ensemblplants:AT4G33000.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0050801"(ion homeostasis) refseq:NP_198391.1|go:"GO:0009651"(response to salt stress)|go:"GO:0009705"(plant-type vacuole membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR004041(NAF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018451|rcsb pdb:2EHB|rcsb pdb:4D28|go:"GO:0006468"(protein phosphorylation)|ensemblplants:AT5G35410(gene)|ensemblplants:AT5G35410.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-34745N go:"GO:0009705"(plant-type vacuole membrane) - - figure legend:Figure 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4100(nicbe)|taxid:4100(Nicotiana benthamiana) - 2008/10/30 2019/08/07 rogid:MSTiLDXo1HYv3JPt4kFnlvlpjBY3702 rogid:RQgXuL8VS8nwPMEDigV1GP36hR43702 intact-crc:4DC2C52ACBAAF122|rigid:vRAwjapIsRhl5bR0Dmn9j9oI8QM false yellow fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)