#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q17390	uniprotkb:Q19213	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1811333|ensemblmetazoa:F08G12.4.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:vhl_caeel(display_long)|uniprotkb:vhl-1(gene name)|psi-mi:vhl-1(display_short)|uniprotkb:F08G12.4(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_509889.1|wormbase:F08G12.4|interpro:IPR024053|interpro:IPR022772|interpro:IPR036208|interpro:IPR037140|mint:Q19213|ensemblmetazoa:F08G12.4.1(transcript)|ensemblmetazoa:WBGene00006922(gene)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|reactome:R-CEL-1234176|reactome:R-CEL-3232142|reactome:R-CEL-8951664|reactome:R-CEL-9706019|reactome:R-CEL-983168	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:ssahaPgjW6jqdgoGQ9PJKRmEWXU6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:Q2WF59	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1811352|uniprotkb:Q2WF58|ensemblmetazoa:T24C4.6b.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:zer1_caeel(display_long)|uniprotkb:zer-1(gene name)|psi-mi:zer-1(display_short)|uniprotkb:zyg-11-related protein(gene name synonym)|uniprotkb:T24C4.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_741089.2|refseq:NP_741090.3|wormbase:T24C4.6a|wormbase:T24C4.6b|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q2WF59|interpro:IPR040368|ensemblmetazoa:T24C4.6b.1(transcript)|ensemblmetazoa:WBGene00020762(gene)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:sYAPyQAgo/z/Z3djkMCnpyqQqC46239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:G5ED41	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1998180|ensemblmetazoa:Y102A5A.1.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:cand1_caeel(display_long)|uniprotkb:cand-1(gene name)|psi-mi:cand-1(display_short)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:Y102A5A.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	uniprotkb:Q9XTJ0(uniprot-removed-ac)|reactome:R-CEL-6798695|interpro:IPR039852|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|refseq:NP_507244.1|wormbase:Y102A5A.1|reactome:R-CEL-8951664|reactome:R-CEL-917937|ensemblmetazoa:WBGene00013606(gene)|ensemblmetazoa:Y102A5A.1.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0060625"(regulation of protein deneddylation)	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:EHWL7rY0EFeJ0YOm0XvMjCDf+To6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:Q23457	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1998112|uniprotkb:Q8WSQ1|ensemblmetazoa:ZK287.5.1|ensemblmetazoa:ZK287.5.2	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:rbx1_caeel(display_long)|uniprotkb:rbx-1(gene name)|psi-mi:rbx-1(display_short)|uniprotkb:Ce-rbx-1(gene name synonym)|uniprotkb:ZK287.5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_505496.1|wormbase:ZK287.5|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:Q23457|ensemblmetazoa:WBGene00004320(gene)|ensemblmetazoa:ZK287.5.1(transcript)|ensemblmetazoa:ZK287.5.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0051301"(cell division)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|reactome:R-CEL-110314|reactome:R-CEL-1234176|reactome:R-CEL-195253|reactome:R-CEL-5632684|reactome:R-CEL-5696394|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-68949|reactome:R-CEL-8854050|reactome:R-CEL-8932339|reactome:R-CEL-8939902|reactome:R-CEL-8951664|reactome:R-CEL-983168|reactome:R-CEL-4641258	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:K9YFXD2x8iuzCtYyPx/bYHJnT4Q6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:P17221	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:P21541	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-314647|ensemblmetazoa:C08B11.1.1|ensemblmetazoa:C08B11.1.2	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:zyg11_caeel(display_long)|uniprotkb:zyg-11(gene name)|psi-mi:zyg-11(display_short)|uniprotkb:C08B11.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_495677.1|wormbase:C08B11.1|mint:P21541|ensemblmetazoa:C08B11.1.1(transcript)|ensemblmetazoa:C08B11.1.2(transcript)|ensemblmetazoa:WBGene00006996(gene)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|dip:DIP-25221N	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:IvEYs/5a9zl+UnC6/ZB36CQuuxY6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:G5ECR7	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:Q9BKS1	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998090|imex:IM-20110-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 1A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:6440EC52EE5571B4|rigid:tKYuXmDJhWveBPCwuFpRIthh0OE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P17221	uniprotkb:Q9BKS1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998208|imex:IM-20110-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:8EFEDFE445CF27C2|rigid:87eZIBxKpHv210ww1xb8djX0HBQ	false	flag tag:n-n|binding-associated region:541-548	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17221	uniprotkb:P34708-1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998284|imex:IM-20110-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 5A, 6A|stimulant:"Interaction is observed only in the presence of the proteasome inhibitor N-acetyl-L-leucinyl- L-leucinal-L-norleucinal (LLnL)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:2A23AD8838AABC48|rigid:eW4/Ez+IPDOjBfr5XWsv4HCyFuA	false	flag tag:n-n	t7 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17221	uniprotkb:Q13617	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998301|imex:IM-20110-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	-	-	-	figure legend:Fig 5B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	intact-crc:DDBD40B94ABDC5CD|rigid:qRB/VbJTpZep5X4mZA4AaIPglo4	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49594	uniprotkb:P34708-1	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998417|imex:IM-20110-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 6A|stimulant:"Interaction is observed only in the presence of the proteasome inhibitor N-acetyl-L-leucinyl- L-leucinal-L-norleucinal (LLnL)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:F575C103A73F9F6E|rigid:WMSsQaUAlSxkdD1m8e8zNXZ2ya8	false	vsv tag:n-n	t7 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34708-1	uniprotkb:P34691	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998426|imex:IM-20110-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6A|stimulant:"Interaction is observed only in the presence of the proteasome inhibitor N-acetyl-L-leucinyl- L-leucinal-L-norleucinal (LLnL)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:B8E5B7B0173A877E|rigid:bw/GxMh6HqJzg89BotOtt99fLOg	false	t7 tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17221	uniprotkb:P49594	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998492|imex:IM-20110-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	intact-crc:3A3D979A647C952B|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	flag tag:n-n	vsv tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17221	uniprotkb:P34691	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998492|imex:IM-20110-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:3A3D979A647C952B|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	flag tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49594	uniprotkb:P17221	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998517|imex:IM-20110-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	intact-crc:3BC9575A2FEA90BD|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	vsv tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49594	uniprotkb:P34691	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998517|imex:IM-20110-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:3BC9575A2FEA90BD|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	vsv tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34691	uniprotkb:P49594	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998528|imex:IM-20110-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	intact-crc:AD019A81DDE78CB4|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	v5 tag:n-n	vsv tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34691	uniprotkb:P17221	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998528|imex:IM-20110-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	intact-crc:AD019A81DDE78CB4|rigid:fTSIL/V9E0AcjCcLzWugamIbLDg	false	v5 tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BKS1	uniprotkb:P49594	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998547|imex:IM-20110-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	-	-	-	figure legend:Fig 6E, 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	intact-crc:15E968115F91C837|rigid:CYQjgRarHFodX0hjUFxnOz7E8v0	false	ha tag:n-n	vsv tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BKS1	uniprotkb:P17221	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998547|imex:IM-20110-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6E, 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	intact-crc:15E968115F91C837|rigid:CYQjgRarHFodX0hjUFxnOz7E8v0	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BKS1	uniprotkb:Q13617	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998547|imex:IM-20110-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	-	-	-	figure legend:Fig 6E, 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	intact-crc:15E968115F91C837|rigid:CYQjgRarHFodX0hjUFxnOz7E8v0	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BKS1	uniprotkb:P34708-1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998547|imex:IM-20110-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 6E, 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:15E968115F91C837|rigid:CYQjgRarHFodX0hjUFxnOz7E8v0	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BKS1	uniprotkb:P34691	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998547|imex:IM-20110-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6E, 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2008/09/25	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:15E968115F91C837|rigid:CYQjgRarHFodX0hjUFxnOz7E8v0	false	ha tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17221	uniprotkb:Q9BKS1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998245|imex:IM-20110-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:F8D2AE0603E9479E|rigid:87eZIBxKpHv210ww1xb8djX0HBQ	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P49594	uniprotkb:P17221	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998435|imex:IM-20110-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	intact-crc:8A4B6A1F2738875D|rigid:KJZo2MznwUUgidlgJuOgmJ5ZXPQ	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P49594	uniprotkb:P34708-1	intact:EBI-1998402|ensemblmetazoa:T19C3.8.1|ensemblmetazoa:T19C3.8.2	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:fem2_caeel(display_long)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase"(gene name synonym)|uniprotkb:fem-2(gene name)|psi-mi:fem-2(display_short)|uniprotkb:Sex-determining protein fem-2(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 2(gene name synonym)|uniprotkb:T19C3.8(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998459|imex:IM-20110-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_497224.1|wormbase:T19C3.8|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|rcsb pdb:4JND|interpro:IPR036457|ensemblmetazoa:T19C3.8.1(transcript)|ensemblmetazoa:T19C3.8.2(transcript)|ensemblmetazoa:WBGene00001412(gene)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:R70Rc3Xej/Sikn9mEg+MTaYT4eE6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:CD2291001465916C|rigid:WMSsQaUAlSxkdD1m8e8zNXZ2ya8	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P34691	uniprotkb:P34708-1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998467|imex:IM-20110-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:87FB67DB1E214BC8|rigid:bw/GxMh6HqJzg89BotOtt99fLOg	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P17221	uniprotkb:P34691	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-445465|ensemblmetazoa:C01F6.4a.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:fem3_caeel(display_long)|uniprotkb:Feminization of XX and XO animals protein 3(gene name synonym)|uniprotkb:Ce-FEM-3(gene name synonym)|uniprotkb:C01F6.4(orf name)|uniprotkb:fem-3(gene name)|psi-mi:fem-3(display_short)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998475|imex:IM-20110-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	ensemblmetazoa:C01F6.4a.1(transcript)|ensemblmetazoa:WBGene00001413(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030238"(male sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043406"(positive regulation of MAP kinase activity)|interpro:IPR030804|refseq:NP_001255365.1|wormbase:C01F6.4a|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1904146"(positive regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1905936"(regulation of germ cell proliferation)	-	-	-	figure legend:Fig 6B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:3WeE4VQ4oQC4FjKX7mUkJ/kWfGo6239	intact-crc:5A2C4E20731BCF47|rigid:C3Zq5KpbKPO/sfUlt2xFR+m9JlM	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P17221	uniprotkb:P34708-1	intact:EBI-1998155|uniprotkb:Q95ZU3|ensemblmetazoa:F35D6.1a.1	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:fem1_caeel(display_long)|uniprotkb:fem-1(gene name)|psi-mi:fem-1(display_short)|uniprotkb:isx-1(gene name synonym)|uniprotkb:Feminization of XX and XO animals protein 1(gene name synonym)|uniprotkb:F35D6.1(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0096"(pull down)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998484|imex:IM-20110-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_500824.1|refseq:NP_500825.1|interpro:IPR020683|wormbase:F35D6.1a|wormbase:F35D6.1b|interpro:IPR002110(Ankyrin)|reactome:R-CEL-8951664|interpro:IPR036770|interpro:IPR011990(Tetratricopeptide-like helical)|ensemblmetazoa:F35D6.1a.1(transcript)|ensemblmetazoa:WBGene00001411(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:1905936"(regulation of germ cell proliferation)	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 6C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/09/25	2014/10/16	rogid:iq2eqvK7y3FrsolQmLrQdqg4gu46239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:F3F6AD6EA24A999C|rigid:eW4/Ez+IPDOjBfr5XWsv4HCyFuA	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q17390	uniprotkb:P34708-1	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-367214|ensemblmetazoa:Y47D3A.6a.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:p34708-1(display_long)|uniprotkb:Tra-1L(isoform synonym)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Starostina et al. (2007)	pubmed:17609115|imex:IM-20110	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1998363|imex:IM-20110-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	intact:EBI-367204(tra1_caeel)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)	-	-	-	figure legend:Fig 5C|stimulant:Interaction is observed only when pbs-4 RNAi is used to inactivate the proteasome.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2008/09/25	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239	intact-crc:28F0A7ABF1D15099|rigid:8NeBvCXwBobZI4LB73fQjCO+0s4	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)