#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646610|imex:IM-20014-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:34C03C3E81622F94|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	sufficient binding region:2167-2701	sufficient binding region:212-424	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646624|imex:IM-20014-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Figs. 1A and 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:799F605C9990D4A0|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	sufficient binding region:2167-2701	necessary binding region:341-424	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BZD4	uniprotkb:Q02224	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646639|imex:IM-20014-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	-	-	-	figure legend:Figs. 1C and 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/03/07	2015/02/12	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	intact-crc:EDEC1EF3F4F6EDB8|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	necessary binding region:341-424|green fluorescent protein tag:?-?	sufficient binding region:2167-2701|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646652|imex:IM-20014-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:E2077C2970D95911|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	sufficient binding region:2167-2701|maltose binding protein tag:?-?	sufficient binding region:281-464|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646673|imex:IM-20014-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:379F015067743845|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646678|imex:IM-20014-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:5EE700C257D18702|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646690|imex:IM-20014-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	-	-	-	figure legend:Fig. 2B|delivery method:Q9BZD4 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:6103185B07D1ADD6|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	-	necessary binding region:341-424|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BZD4	uniprotkb:Q02224	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646707|imex:IM-20014-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	go:"GO:0000776"(kinetochore)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2015/02/12	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	intact-crc:D93D411B4EE79794|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O14777	uniprotkb:Q02224	intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym)	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646715|imex:IM-20014-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	go:"GO:0000776"(kinetochore)	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2014/10/16	rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	intact-crc:F5B1FBFD7F4D147A|rigid:ogxHeJHqNuJnZFA7skZaEdgYfo8	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q02224	uniprotkb:Q9BZD4	intact:EBI-1375040|uniprotkb:A6NKY9|uniprotkb:Q4LE75|uniprotkb:A8K2U7|ensembl:ENSP00000265148	intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78	psi-mi:cenpe_human(display_long)|uniprotkb:CENPE(gene name)|psi-mi:CENPE(display_short)|uniprotkb:Kinesin-related protein CENPE(gene name synonym)|uniprotkb:Centromere protein E(gene name synonym)|uniprotkb:Kinesin-7(gene name synonym)	psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2007)	pubmed:17535814|imex:IM-20014	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1646721|imex:IM-20014-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001804.2|refseq:NP_001273663.1|dip:DIP-38902N|ensembl:ENSG00000138778(gene)|ensembl:ENST00000265148(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0099606"(microtubule plus-end directed mitotic chromosome migration)|go:"GO:0099607"(lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q02224|rcsb pdb:1T5C|rcsb pdb:5JVP|rcsb pdb:6M4I|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-983189	refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N	go:"GO:0000776"(kinetochore)	-	-	figure legend:Fig. 3D|delivery method:Q9BZD4 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/03/07	2015/02/12	rogid:SbcZI5/nK0DHyrfEA5VBMSq4mX49606	rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606	intact-crc:CAC7A0706927B003|rigid:9BhAPJbpObHjuKkcEtByBpzMvGA	false	-	sufficient binding region:341-424|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)