#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12118 uniprotkb:P31539 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-8050|uniprotkb:D6VXX8|ensemblfungi:YLL026W psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:hs104_yeast(display_long)|uniprotkb:HSP104(gene name)|psi-mi:HSP104(display_short)|uniprotkb:YLL026W(locus name)|uniprotkb:L0948(orf name)|uniprotkb:Protein aggregation-remodeling factor HSP104(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 sgd:S000003949|refseq:NP_013074.1|mint:P31539|dip:DIP-2252N|ensemblfungi:YLL026W(gene)|ensemblfungi:YLL026W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0043531"(ADP binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070414"(trehalose metabolism in response to heat stress)|go:"GO:0072380"(TRC complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR028299|interpro:IPR036628|interpro:IPR041546|rcsb pdb:5KNE|rcsb pdb:5U2U|rcsb pdb:5VJH|rcsb pdb:5VY8|rcsb pdb:5VY9|rcsb pdb:5VYA|rcsb pdb:5WBW|rcsb pdb:6AHF|rcsb pdb:6AMN|rcsb pdb:6N8T|rcsb pdb:6N8V|rcsb pdb:6N8Z - crc64:33539B74F742BD3C crc64:4AD0E7E3AF98E318 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:rMl56qonOOODJUyLVkkWwUq8Cj4559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12118 uniprotkb:P25491 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 - crc64:33539B74F742BD3C crc64:E4539F3618DD9CF2 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12118 uniprotkb:P15108 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010 psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N - crc64:33539B74F742BD3C crc64:DBD41524091B1F9B figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12118 uniprotkb:Q12285 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:33539B74F742BD3C crc64:CE6FC4282E0E472C figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12118 uniprotkb:P10591 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-8591|uniprotkb:D6VPL2|ensemblfungi:YAL005C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:hsp71_yeast(display_long)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short)|uniprotkb:Heat shock protein YG100(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_009396.2|sgd:S000000004|mint:P10591|dip:DIP-2253N|ensemblfungi:YAL005C(gene)|ensemblfungi:YAL005C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3LCA|rcsb pdb:5LYN|rcsb pdb:5Z8I|rcsb pdb:5Z8Q - crc64:33539B74F742BD3C crc64:249D8A3BC42527CA figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12118 uniprotkb:P10592 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-8603|uniprotkb:D6VXY0|ensemblfungi:YLL024C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782119|imex:IM-19337-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_013076.1|sgd:S000003947|mint:P10592|dip:DIP-2265N|ensemblfungi:YLL024C(gene)|ensemblfungi:YLL024C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-SCE-3371497|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|reactome:R-SCE-8876725 - crc64:33539B74F742BD3C crc64:129049E21C9DD1F3 figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:FakCbxCBdOtSSqw2C4u76D3opS0559292 intact-crc:B8CD857FBF3707A0|rigid:4Hs0FtfcKGeB2aKQTEPQpkfbIno false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12285 uniprotkb:P25491 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782144|imex:IM-19337-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 - crc64:CE6FC4282E0E472C crc64:E4539F3618DD9CF2 figure legend:"Fig: 5A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 intact-crc:233751C69FFEABAF|rigid:zm42UTrDhttV1ijO4rcZXkW7SI0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12285 uniprotkb:Q12118 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782144|imex:IM-19337-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 - crc64:CE6FC4282E0E472C crc64:33539B74F742BD3C figure legend:"Fig: 5A"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 intact-crc:233751C69FFEABAF|rigid:zm42UTrDhttV1ijO4rcZXkW7SI0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12285 uniprotkb:Q12118 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:"MI:0018"(two hybrid) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782154|imex:IM-19337-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 - crc64:CE6FC4282E0E472C crc64:33539B74F742BD3C figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/06/12 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 intact-crc:F7B5A0EF785FA9E6|rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y false - binding-associated region:1-111 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12118 uniprotkb:Q12285 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0096"(pull down) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1782172|imex:IM-19337-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:33539B74F742BD3C crc64:CE6FC4282E0E472C figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/06/12 2014/10/16 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:A98B421ACFEEB661|rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y false binding-associated region:1-111 glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25491 uniprotkb:Q12285 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:"MI:0096"(pull down) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782180|imex:IM-19337-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK - crc64:E4539F3618DD9CF2 crc64:CE6FC4282E0E472C figure legend:Fig. 5C|comment:The interaction is the same in presence or absence of Sgt2.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/06/12 2014/10/16 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 intact-crc:BC6701C4301A4F09|rigid:IINDZ9K4T/JFGKVFQMNe6edB5w8 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12285 uniprotkb:Q12118 intact:EBI-34904|uniprotkb:D6W1V6|ensemblfungi:YOL111C intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C psi-mi:mdy2_yeast(display_long)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name) psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:"MI:0096"(pull down) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782187|imex:IM-19337-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014530.1|sgd:S000005471|mint:Q12285|dip:DIP-1982N|ensemblfungi:YOL111C(gene)|ensemblfungi:YOL111C_mRNA(transcript)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR031765|interpro:IPR040474|rcsb pdb:2LNZ|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:2WPV|rcsb pdb:3LKU|rcsb pdb:3VEJ|rcsb pdb:3ZDM|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:4PWX|rcsb pdb:5BW8|rcsb pdb:5BWK refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 - crc64:CE6FC4282E0E472C crc64:33539B74F742BD3C figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/06/12 2014/10/16 rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 intact-crc:991072FD89EC453B|rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y false - glutathione s tranferase tag:?-?|necessary binding region:1-68 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25491 uniprotkb:Q12118 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 intact:EBI-31784|uniprotkb:D6W273|ensemblfungi:YOR007C psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) psi-mi:"MI:0096"(pull down) Liou et al. (2007) pubmed:17441508|imex:IM-19337 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1782418|imex:IM-19337-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 refseq:NP_014649.1|sgd:S000005533|dip:DIP-1983N|mint:Q12118|ensemblfungi:YOR007C(gene)|ensemblfungi:YOR007C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072380"(TRC complex)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:3ZDM|rcsb pdb:4ASV|rcsb pdb:4ASW|rcsb pdb:5LYN|rcsb pdb:5LYP|reactome:R-SCE-9609523 - crc64:E4539F3618DD9CF2 crc64:33539B74F742BD3C figure legend:Fig. 6C|comment:The presence of residues 1 to 58 of SGT2 increase the interaction and the presence of Mdy2 also increases slightly the interaction.|stimulant:Mdy2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/06/12 2014/10/16 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 intact-crc:F962C76B9700066A|rigid:0j3ifPV5GEYjdfcKurfa1ehvwqc false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)