#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P14904 uniprotkb:Q12421 intact:EBI-2571|uniprotkb:P22060|uniprotkb:D6VXI5|ensemblfungi:YKL103C intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C psi-mi:ampl_yeast(display_long)|uniprotkb:APE1(gene name)|psi-mi:APE1(display_short)|uniprotkb:API(gene name synonym)|uniprotkb:Aminopeptidase yscI(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:Leucine aminopeptidase IV(gene name synonym)|uniprotkb:Lysosomal aminopeptidase III(gene name synonym)|uniprotkb:Polypeptidase(gene name synonym)|uniprotkb:Vacuolar aminopeptidase I(gene name synonym)|uniprotkb:YSC1(gene name synonym)|uniprotkb:YKL455(orf name)|uniprotkb:YKL103C(locus name) psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:"MI:0416"(fluorescence microscopy) Kabeya et al. (2007) pubmed:17362880|imex:IM-19018 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-2014191|imex:IM-19018-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012819.1|sgd:S000001586|dip:DIP-1409N|ensemblfungi:YKL103C(gene)|ensemblfungi:YKL103C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034270"(Cvt complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4R8F|rcsb pdb:5JGE|rcsb pdb:5JGF|rcsb pdb:5JH9|rcsb pdb:5JHC|rcsb pdb:5JM9 refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 - crc64:702A8C88A2124C24 crc64:CC2396854F29D250 figure legend:Fig.3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/17 2014/10/16 rogid:MbMMYXKaMfqP7VgVhjt5sN+tyq0559292 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 intact-crc:5B3CF5FE5A7ACA60|rigid:TklabOVS0zNO8qJMzp8j8j6X6ZY false red fluorescent protein tag:n-n green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06410 uniprotkb:Q12421 intact:EBI-30856|uniprotkb:D6VZ59|ensemblfungi:YLR423C intact:EBI-34768|uniprotkb:Q03939|uniprotkb:D6VS08|ensemblfungi:YDR022C psi-mi:atg17_yeast(display_long)|uniprotkb:ATG17(gene name)|psi-mi:ATG17(display_short)|uniprotkb:APG17(gene name synonym)|uniprotkb:YLR423C(locus name) psi-mi:atg31_yeast(display_long)|uniprotkb:ATG31(gene name)|psi-mi:ATG31(display_short)|uniprotkb:CIK1 suppressor protein 1(gene name synonym)|uniprotkb:CIS1(gene name synonym)|uniprotkb:Protein CIS1(gene name synonym)|uniprotkb:PZD196(orf name)|uniprotkb:YD9335.08c(orf name)|uniprotkb:YDR022C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kabeya et al. (2007) pubmed:17362880|imex:IM-19018 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-2014205|imex:IM-19018-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004415|refseq:NP_013527.3|dip:DIP-1490N|mint:Q06410|ensemblfungi:YLR423C(gene)|ensemblfungi:YLR423C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045772"(positive regulation of autophagosome size)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR007240(Autophagy protein 17) refseq:NP_010305.1|sgd:S000002429|mint:Q12421|dip:DIP-2667N|ensemblfungi:YDR022C(gene)|ensemblfungi:YDR022C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000741"(karyogamy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006914"(autophagy)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018621 - crc64:71504B6C76549B75 crc64:CC2396854F29D250 figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/17 2014/10/16 rogid:cOX1btuNKiBhY8roD022C0NYxG4559292 rogid:qwAx0SPS9A+ufGaQrt+hF2/tggg559292 intact-crc:B75A122DE44BB947|rigid:bjhIW1HyWYMdxOAK03FqqYfnOQ0 false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)