#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68451	uniprotkb:Q16611	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066130|mint:MINT-6629237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629238(identity)|uniprotkb:P68451(P68451)	refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N|mint:MINT-6629240(identity)|uniprotkb:Q16611(Q16611)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F9|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606	intact-crc:ED44B4DD10331692|rigid:99csq7eRyeVBGSTRwWbWtLZV1FQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:O43521	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066156|mint:MINT-6629247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629248(identity)|uniprotkb:P68451(P68451)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N|mint:MINT-6629250(identity)|uniprotkb:O43521(O43521)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F10|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	intact-crc:BFD677CF7F2FE4F9|rigid:qehZ61mP/t9hhDq1sS8BG6d/7IE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:Q07812	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-516580|uniprotkb:P55269|uniprotkb:Q07814|uniprotkb:Q07815|uniprotkb:Q8WZ49|uniprotkb:Q9NR76|uniprotkb:Q9UQD6|uniprotkb:Q9NYG7|uniprotkb:Q9UCZ6|uniprotkb:Q9UCZ7|uniprotkb:A8K4W1|intact:EBI-8995042|ensembl:ENSP00000263262	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:bax_human(display_long)|uniprotkb:BAX(gene name)|psi-mi:BAX(display_short)|uniprotkb:BCL2L4(gene name synonym)|uniprotkb:Bcl-2-like protein 4(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066143|mint:MINT-6629242	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629243(identity)|uniprotkb:P68451(P68451)	refseq:NP_004315.1|refseq:NP_620116.1|refseq:NP_620118.1|refseq:NP_620119.2|refseq:XP_016882566.1|refseq:NP_001278357.1|refseq:NP_001278360.1|dip:DIP-232N|ensembl:ENSG00000087088(gene)|ensembl:ENST00000345358(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001764"(neuron migration)|go:"GO:0001777"(T cell homeostatic proliferation)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001822"(kidney development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001844"(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007281"(germ cell development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009651"(response to salt stress)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032976"(release of matrix enzymes from mitochondria)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045136"(development of secondary sexual characteristics)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048087"(positive regulation of developmental pigmentation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048678"(response to axon injury)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051087"(chaperone binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097144"(BAX complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015267"(channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021854"(hypothalamus development)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1990117"(B cell receptor apoptotic signaling pathway)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026304|interpro:IPR036834|mint:Q07812|rcsb pdb:1F16|rcsb pdb:2G5B|rcsb pdb:2K7W|rcsb pdb:2LR1|rcsb pdb:3PK1|rcsb pdb:3PL7|rcsb pdb:4BD2|rcsb pdb:4BD6|rcsb pdb:4BD7|rcsb pdb:4BD8|rcsb pdb:4BDU|rcsb pdb:4S0O|rcsb pdb:4S0P|rcsb pdb:4UF2|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIG|rcsb pdb:4ZIH|rcsb pdb:4ZII|rcsb pdb:5W5X|rcsb pdb:5W5Z|rcsb pdb:5W60|rcsb pdb:5W61|rcsb pdb:6EB6|rcsb pdb:6L8V|rcsb pdb:6L95|rcsb pdb:6TRR|rcsb pdb:6XY6|reactome:R-HSA-111457|reactome:R-HSA-114294|reactome:R-HSA-5620971|reactome:R-HSA-6803204|reactome:R-HSA-6804114|reactome:R-HSA-8878166|reactome:R-HSA-9603505|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|mint:MINT-6629245(identity)|uniprotkb:Q07812(Q07812)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F9|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:+Fz2No3HFxN4vZ+KGhDcgPQhpLo9606	intact-crc:6250092726147A79|rigid:NYGdldSjTPaVWlj1Q/eGU56dnd4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43521	uniprotkb:P10415	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	intact:EBI-77694|ensembl:ENSP00000329623|ensembl:ENSP00000381185|uniprotkb:P10416|uniprotkb:Q13842|uniprotkb:Q16197|uniprotkb:C9JHD5	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:bcl2_human(display_long)|uniprotkb:BCL2(gene name)|psi-mi:BCL2(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066169|mint:MINT-6629252	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N|mint:MINT-6629255(identity)|uniprotkb:O43521(O43521)	interpro:IPR020728|interpro:IPR020731|interpro:IPR026298|interpro:IPR036834|rcsb pdb:4LVT|rcsb pdb:4LXD|rcsb pdb:4MAN|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5FCG|rcsb pdb:5JSN|rcsb pdb:5VAU|rcsb pdb:5VAX|rcsb pdb:5VAY|rcsb pdb:6GL8|rcsb pdb:6IWB|rcsb pdb:6O0K|rcsb pdb:6O0L|rcsb pdb:6O0M|rcsb pdb:6O0O|rcsb pdb:6O0P|rcsb pdb:7LHB|reactome:R-HSA-111447|reactome:R-HSA-111453|reactome:R-HSA-6785807|reactome:R-HSA-844455|reactome:R-HSA-9018519|reactome:R-HSA-9634638|mint:P10415|rcsb pdb:1G5M|rcsb pdb:1GJH|rcsb pdb:1YSW|rcsb pdb:2O21|rcsb pdb:2O22|rcsb pdb:2O2F|rcsb pdb:2W3L|rcsb pdb:2XA0|rcsb pdb:4AQ3|rcsb pdb:4IEH|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015267"(channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016248"(channel inhibitor activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|ensembl:ENSG00000171791(gene)|ensembl:ENST00000333681(transcript)|ensembl:ENST00000398117(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002931"(response to ischemia)|go:"GO:0031103"(axon regeneration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032835"(glomerulus development)|go:"GO:0032848"(negative regulation of cellular pH reduction)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034097"(response to cytokine)|go:"GO:0035094"(response to nicotine)|go:"GO:0035265"(organ growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043375"(CD8-positive, alpha-beta T cell lineage commitment)|go:"GO:0003014"(renal system process)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007015"(actin filament organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009314"(response to radiation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010039"(response to iron ion)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048536"(spleen development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048599"(oocyte development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0048753"(pigment granule organization)|go:"GO:0043583"(ear development)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0046671"(negative regulation of retinal cell programmed cell death)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR004725(Apoptosis regulator Bcl-X protein)|interpro:IPR013278(Apoptosis regulator, Bcl-2)|interpro:IPR020717|interpro:IPR020726|go:"GO:0051924"(regulation of calcium ion transport)|refseq:NP_000624.2|dip:DIP-1043N|refseq:NP_000648.2|mint:MINT-6629253(identity)|uniprotkb:P10415(P10415)	-	-	-	figure legend:F10|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	rogid:XC215VuR7Wf2ACXOm1pTyyuimSU9606	intact-crc:965EA6052BE86DD2|rigid:sH6H+AHuNTu0woxvGjrRc1eNEtI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:O43521	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066221|mint:MINT-6629267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629271(identity)|uniprotkb:P68451(P68451)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N|mint:MINT-6629268(identity)|uniprotkb:O43521(O43521)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F11C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	intact-crc:23DB438148214355|rigid:qehZ61mP/t9hhDq1sS8BG6d/7IE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P68451	uniprotkb:O43521	intact:EBI-7066119|uniprotkb:P21091|intact:MINT-6629061	intact:EBI-526406|uniprotkb:Q0MSE7|uniprotkb:Q0MSE8|uniprotkb:Q0MSE9|uniprotkb:Q53R28|uniprotkb:Q6JTU6|uniprotkb:Q6T851|uniprotkb:Q6TE14|uniprotkb:Q6TE15|uniprotkb:Q6TE16|uniprotkb:Q6V402|uniprotkb:A8K2W2|uniprotkb:Q8WYL6|uniprotkb:Q8WYL7|uniprotkb:Q8WYL8|uniprotkb:Q8WYL9|uniprotkb:Q8WYM0|uniprotkb:Q8WYM1|uniprotkb:O43522|intact:EBI-1002160|ensembl:ENSP00000376943	psi-mi:f1_vaccp(display_long)|uniprotkb:F1L(orf name)	psi-mi:b2l11_human(display_long)|uniprotkb:BCL2L11(gene name)|psi-mi:BCL2L11(display_short)|uniprotkb:BIM(gene name synonym)|uniprotkb:Bcl2-interacting mediator of cell death(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Taylor et al. (2006)	pubmed:17074758|mint:MINT-6629231	taxid:31531(vaccp)|taxid:31531("Vaccinia virus (strain L-IVP) (VACV)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7066193|mint:MINT-6629259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P68451|go:"GO:0019050"(suppression by virus of host apoptotic process)|interpro:IPR021119|interpro:IPR011207(Uncharacterized conserved protein UCP015971, VAC-F1L)|interpro:IPR036834|mint:MINT-6629260(identity)|uniprotkb:P68451(P68451)	refseq:NP_001191035.1|refseq:NP_001191036.1|refseq:NP_001191037.1|refseq:NP_001191038.1|refseq:NP_001191039.1|refseq:NP_001191040.1|refseq:NP_001191041.1|refseq:NP_001191042.1|refseq:NP_006529.1|refseq:NP_619527.1|refseq:NP_619528.1|refseq:NP_619529.1|refseq:NP_619530.1|refseq:NP_619531.1|refseq:NP_619532.1|refseq:NP_619533.1|refseq:NP_996885.1|refseq:NP_996886.1|ensembl:ENSG00000153094(gene)|ensembl:ENST00000393256(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001822"(kidney development)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007127"(meiosis I)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008584"(male gonad development)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0012505"(endomembrane system)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030879"(mammary gland development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0034263"(positive regulation of autophagy in response to ER overload)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035148"(tube formation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043583"(ear development)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097140"(BIM-BCL-xl complex)|go:"GO:0097141"(BIM-BCL-2 complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1902110"(positive regulation of mitochondrial membrane permeability involved in apoptotic process)|reactome:R-HSA-111453|reactome:R-HSA-193648|reactome:R-HSA-6802952|reactome:R-HSA-8862803|reactome:R-HSA-8952158|reactome:R-HSA-9607240|reactome:R-HSA-9614657|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014771(Apoptosis, Bim N-terminal)|interpro:IPR015040(Bcl-x interacting)|interpro:IPR017288(Apoptosis, Bcl-2-like protein 11)|mint:O43521|rcsb pdb:1F95|rcsb pdb:2K7W|rcsb pdb:2NL9|rcsb pdb:2V6Q|rcsb pdb:2VM6|rcsb pdb:2WH6|rcsb pdb:2YQ6|rcsb pdb:2YQ7|rcsb pdb:3D7V|rcsb pdb:3FDL|rcsb pdb:3IO8|rcsb pdb:3IO9|rcsb pdb:3KJ0|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:4A1U|rcsb pdb:4A1W|rcsb pdb:4B4S|rcsb pdb:4D2M|rcsb pdb:4QVF|rcsb pdb:4UF3|rcsb pdb:4YJ4|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIH|rcsb pdb:5AGW|rcsb pdb:5AGX|rcsb pdb:5C3G|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX2|rcsb pdb:5VX3|rcsb pdb:5WOS|rcsb pdb:6QFI|rcsb pdb:6RJP|rcsb pdb:6TQQ|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6VBX|rcsb pdb:6X8O|reactome:R-HSA-111446|dip:DIP-29185N|mint:MINT-6629263(identity)|uniprotkb:O43521(O43521)	-	comment:"fragmentation type: fragment"|comment:mint	-	figure legend:F11B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|curation depth:rapid curation	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2008/06/26	2014/10/16	rogid:8/tlI/TrxzhDdoIWa9PQpYrcPMA31531	rogid:YvDxFP1kVEoSiz67PVpE4ZM5wWI9606	intact-crc:ADD1AC4D7B99624F|rigid:qehZ61mP/t9hhDq1sS8BG6d/7IE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)