#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UPN7 uniprotkb:O00743 intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521 intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648 psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym) psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stefansson et al. (2006) pubmed:16769727|imex:IM-20107|mint:MINT-8208117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1995803|imex:IM-20107-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/09/23 2014/10/16 rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606 rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606 intact-crc:47153B1B3AE6BC5E|rigid:jvrTcIRGtozAVmhGFQORwsCPGXY false flag tag:?-?|binding-associated region:10-403 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75170 uniprotkb:O00743 intact:EBI-359739|uniprotkb:A6PVG3|uniprotkb:Q7Z5G5|uniprotkb:Q9UGB9|uniprotkb:B7Z7T3|uniprotkb:Q5U5P3|uniprotkb:Q7Z2L2|uniprotkb:Q7Z731|intact:EBI-28971113|ensembl:ENSP00000216061 intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648 psi-mi:pp6r2_human(display_long)|uniprotkb:PP6R2(gene name synonym)|uniprotkb:SAPS domain family member 2(gene name synonym)|uniprotkb:PPP6R2(gene name)|psi-mi:PPP6R2(display_short)|uniprotkb:KIAA0685(gene name synonym)|uniprotkb:SAPS2(gene name synonym) psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stefansson et al. (2006) pubmed:16769727|imex:IM-20107|mint:MINT-8208117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1995811|imex:IM-20107-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229827.1|refseq:NP_001229828.1|refseq:NP_001229829.1|refseq:NP_055493.2|ensembl:ENSP00000216061|ensembl:ENST00000359139|ensembl:ENSP00000352051|ensembl:ENST00000395741|ensembl:ENSP00000379090|ensembl:ENST00000395744|ensembl:ENSP00000379093|ensembl:ENST00000612753|ensembl:ENSP00000478417|ensembl:ENSG00000100239(gene)|ensembl:ENST00000216061(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:XP_006724497.1|refseq:XP_016884612.1|refseq:XP_016884613.1|refseq:XP_016884617.1|refseq:XP_016884620.1|refseq:XP_016884621.1|dip:DIP-27539N refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/09/23 2014/10/16 rogid:DfPIffAldPgUOqg8CaheKSLnQ2E9606 rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606 intact-crc:A08EDCA6AB295E06|rigid:wz2LGItKwyAFCC+KblkDn53gWpM false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P60510 uniprotkb:P78318 intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995 intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661 psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym) psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stefansson et al. (2006) pubmed:16769727|imex:IM-20107|mint:MINT-8208117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1995817|imex:IM-20107-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase) refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1 - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/09/23 2014/10/16 rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606 rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606 intact-crc:CFFFC66907D91454|rigid:POlr1kBAUvdY80HUwcWXGntmNqI false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00221 uniprotkb:Q9UPN7 intact:EBI-355098|uniprotkb:Q5T9V9|intact:EBI-28973237|ensembl:ENSP00000275015 intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521 psi-mi:ikbe_human(display_long)|uniprotkb:IKBE(gene name synonym)|uniprotkb:NFKBIE(gene name)|psi-mi:NFKBIE(display_short)|uniprotkb:I-kappa-B-epsilon(gene name synonym) psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stefansson et al. (2006) pubmed:16769727|imex:IM-20107|mint:MINT-8208117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1995830|imex:IM-20107-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004547.2|ensembl:ENSP00000275015|ensembl:ENST00000275015(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000146232(gene)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1169091|go:"GO:0005829"(cytosol)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|dip:DIP-27533N refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2008/09/23 2014/10/16 rogid:5TEjEGv4jKRrWPpk6jTR+LF97zA9606 rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606 intact-crc:105C15EA8B564BC4|rigid:lBnS54tBNKANsLzm+oUYtIrvsKU false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75170 uniprotkb:O00221 intact:EBI-359739|uniprotkb:A6PVG3|uniprotkb:Q7Z5G5|uniprotkb:Q9UGB9|uniprotkb:B7Z7T3|uniprotkb:Q5U5P3|uniprotkb:Q7Z2L2|uniprotkb:Q7Z731|intact:EBI-28971113|ensembl:ENSP00000216061 intact:EBI-355098|uniprotkb:Q5T9V9|intact:EBI-28973237|ensembl:ENSP00000275015 psi-mi:pp6r2_human(display_long)|uniprotkb:PP6R2(gene name synonym)|uniprotkb:SAPS domain family member 2(gene name synonym)|uniprotkb:PPP6R2(gene name)|psi-mi:PPP6R2(display_short)|uniprotkb:KIAA0685(gene name synonym)|uniprotkb:SAPS2(gene name synonym) psi-mi:ikbe_human(display_long)|uniprotkb:IKBE(gene name synonym)|uniprotkb:NFKBIE(gene name)|psi-mi:NFKBIE(display_short)|uniprotkb:I-kappa-B-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Stefansson et al. (2006) pubmed:16769727|imex:IM-20107|mint:MINT-8208117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1995838|imex:IM-20107-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229827.1|refseq:NP_001229828.1|refseq:NP_001229829.1|refseq:NP_055493.2|ensembl:ENSP00000216061|ensembl:ENST00000359139|ensembl:ENSP00000352051|ensembl:ENST00000395741|ensembl:ENSP00000379090|ensembl:ENST00000395744|ensembl:ENSP00000379093|ensembl:ENST00000612753|ensembl:ENSP00000478417|ensembl:ENSG00000100239(gene)|ensembl:ENST00000216061(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:XP_006724497.1|refseq:XP_016884612.1|refseq:XP_016884613.1|refseq:XP_016884617.1|refseq:XP_016884620.1|refseq:XP_016884621.1|dip:DIP-27539N refseq:NP_004547.2|ensembl:ENSP00000275015|ensembl:ENST00000275015(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000146232(gene)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1169091|go:"GO:0005829"(cytosol)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|dip:DIP-27533N - - - figure legend:7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2008/09/23 2014/10/16 rogid:DfPIffAldPgUOqg8CaheKSLnQ2E9606 rogid:5TEjEGv4jKRrWPpk6jTR+LF97zA9606 intact-crc:7AEBF517278C0CEC|rigid:HZlfd0zsASMwNJgOMOXP2iSVx14 false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)