#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A2A8R7 uniprotkb:Q96CG3 intact:EBI-1606384|ensembl:ENSMUSP00000095538 intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231 psi-mi:a2a8r7_mouse(display_long)|uniprotkb:Tut4(gene name)|psi-mi:Tut4(display_short)|uniprotkb:Zcchc11(gene name synonym) psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym) psi-mi:"MI:0096"(pull down) Minoda et al. (2006) pubmed:16643855|imex:IM-19801 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606380|imex:IM-19801-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017175628.1|ensembl:ENSMUSG00000034610(gene)|ensembl:ENSMUST00000097925(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR036875|interpro:IPR043519 refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N - - - figure legend:Fig. 1A|agonist:"Lipopolysaccharide (1ug/ml)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/01/22 2014/10/16 rogid:MAFEGGfnwaOCCD4barU5/0fjrT410090 rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606 intact-crc:7E9994FD5D3F02A0|rigid:j5/8evMPnNOWjANylyIrRdNNpyU false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q5TAX3-1 uniprotkb:Q96CG3 intact:EBI-1606425|ensembl:ENSP00000360599 intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231 psi-mi:q5tax3-1(display_long)|uniprotkb:TUT4(gene name)|psi-mi:TUT4(display_short)|uniprotkb:KIAA0191(gene name synonym)|uniprotkb:ZCCHC11(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 11(gene name synonym) psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Minoda et al. (2006) pubmed:16643855|imex:IM-19801 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606405|imex:IM-19801-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1606413(isoform-parent)|ensembl:ENSG00000134744(gene)|ensembl:ENST00000371544(transcript) refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N - - - figure legend:Fig. 2D|agonist:"Lipopolysaccharide (1ug/ml)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/01/22 2014/10/16 rogid:tjwo/S3PJ2jrLAKL9gt7muDTO0w9606 rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606 intact-crc:9D305B17A29EB46A|rigid:JDjJJbOL+/y+pkYwjxrSKYhPGp4 false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96CG3 uniprotkb:Q5TAX3-1 intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231 intact:EBI-1606425|ensembl:ENSP00000360599 psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym) psi-mi:q5tax3-1(display_long)|uniprotkb:TUT4(gene name)|psi-mi:TUT4(display_short)|uniprotkb:KIAA0191(gene name synonym)|uniprotkb:ZCCHC11(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Minoda et al. (2006) pubmed:16643855|imex:IM-19801 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1606447|imex:IM-19801-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N intact:EBI-1606413(isoform-parent)|ensembl:ENSG00000134744(gene)|ensembl:ENST00000371544(transcript) - - - figure legend:Fig. 2D, 4A|agonist:"Lipopolysaccharide (1ug/ml)"|caution:The shorter form of ZCCHC11 is probably another isoform as a sequence corresponding to this does exist in the mouse, however these is currently no corresponding human sequence in UniProt so it has been annotated as a fragment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2008/01/22 2014/10/16 rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606 rogid:tjwo/S3PJ2jrLAKL9gt7muDTO0w9606 intact-crc:A32FDF78980A1F0D|rigid:JDjJJbOL+/y+pkYwjxrSKYhPGp4 false myc tag:?-? flag tag:n-n|sufficient binding region:191-625 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)