#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75340	uniprotkb:P53355	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	intact:EBI-358616|uniprotkb:Q6ZRZ3|uniprotkb:Q68CP8|uniprotkb:B7ZLD2|uniprotkb:Q1W5W0|ensembl:ENSP00000350785|ensembl:ENSP00000386135|ensembl:ENSP00000417076|ensembl:ENSP00000484267|uniprotkb:Q9BTL8|uniprotkb:Q14CQ7|uniprotkb:B7ZLE7	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:dapk1_human(display_long)|uniprotkb:DAPK1(gene name)|psi-mi:DAPK1(display_short)|uniprotkb:DAPK(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2005)	pubmed:16132846|imex:IM-20026	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1748826|imex:IM-20026-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	ensembl:ENST00000358077(transcript)|ensembl:ENST00000408954(transcript)|ensembl:ENST00000472284(transcript)|ensembl:ENST00000622514(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|ensembl:ENSG00000196730(gene)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020676|interpro:IPR020683|interpro:IPR020859|interpro:IPR027417|interpro:IPR036770|mint:P53355|rcsb pdb:1IG1|rcsb pdb:1JKK|refseq:NP_004929.2|rcsb pdb:1JKL|rcsb pdb:1JKS|rcsb pdb:1JKT|rcsb pdb:1P4F|rcsb pdb:1WVW|rcsb pdb:1WVY|rcsb pdb:1YR5|rcsb pdb:2W4J|rcsb pdb:2W4K|rcsb pdb:2X0G|rcsb pdb:2XUU|rcsb pdb:2XZS|rcsb pdb:1WVX|rcsb pdb:2Y0A|rcsb pdb:2Y4P|rcsb pdb:2Y4V|rcsb pdb:2YAK|rcsb pdb:3DFC|rcsb pdb:3DGK|rcsb pdb:3EH9|rcsb pdb:3EHA|rcsb pdb:3F5G|rcsb pdb:3F5U|rcsb pdb:3GU4|rcsb pdb:3GU5|rcsb pdb:3GU6|rcsb pdb:3GU7|rcsb pdb:3GU8|rcsb pdb:3GUB|rcsb pdb:3ZXT|rcsb pdb:4B4L|rcsb pdb:4PF4|rcsb pdb:4TL0|rcsb pdb:4TXC|rcsb pdb:4UV0|rcsb pdb:4YO4|rcsb pdb:4YPD|rcsb pdb:5AUT|rcsb pdb:5AUU|rcsb pdb:5AUV|rcsb pdb:5AUW|rcsb pdb:5AUX|rcsb pdb:5AUY|rcsb pdb:5AUZ|rcsb pdb:5AV0|rcsb pdb:5AV1|rcsb pdb:5AV2|rcsb pdb:5AV3|rcsb pdb:5AV4|rcsb pdb:6AAR|rcsb pdb:6FHA|rcsb pdb:6FHB|rcsb pdb:6QN4|rcsb pdb:6GY5|rcsb pdb:6IN4|rcsb pdb:6QMO|refseq:NP_001275658.1|refseq:NP_001275659.1|refseq:NP_001275660.1|rcsb pdb:7CCW|rcsb pdb:7CCV|rcsb pdb:7CCU|reactome:R-HSA-418889	-	-	-	author-identifiers:PREY gene NM_004938|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/26	2014/10/16	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rogid:GCxGiQSqtI+M2uqNXe9F4AN1x909606	intact-crc:E57ED84E7AA811C7|rigid:yUNFNCGKS+XqxQ91LmPG/QirAjg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53355	uniprotkb:O75340	intact:EBI-358616|uniprotkb:Q6ZRZ3|uniprotkb:Q68CP8|uniprotkb:B7ZLD2|uniprotkb:Q1W5W0|ensembl:ENSP00000350785|ensembl:ENSP00000386135|ensembl:ENSP00000417076|ensembl:ENSP00000484267|uniprotkb:Q9BTL8|uniprotkb:Q14CQ7|uniprotkb:B7ZLE7	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	psi-mi:dapk1_human(display_long)|uniprotkb:DAPK1(gene name)|psi-mi:DAPK1(display_short)|uniprotkb:DAPK(gene name synonym)	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2005)	pubmed:16132846|imex:IM-20026	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1748839|imex:IM-20026-2	author score:PREY gene NM_004938	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000358077(transcript)|ensembl:ENST00000408954(transcript)|ensembl:ENST00000472284(transcript)|ensembl:ENST00000622514(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|ensembl:ENSG00000196730(gene)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020676|interpro:IPR020683|interpro:IPR020859|interpro:IPR027417|interpro:IPR036770|mint:P53355|rcsb pdb:1IG1|rcsb pdb:1JKK|refseq:NP_004929.2|rcsb pdb:1JKL|rcsb pdb:1JKS|rcsb pdb:1JKT|rcsb pdb:1P4F|rcsb pdb:1WVW|rcsb pdb:1WVY|rcsb pdb:1YR5|rcsb pdb:2W4J|rcsb pdb:2W4K|rcsb pdb:2X0G|rcsb pdb:2XUU|rcsb pdb:2XZS|rcsb pdb:1WVX|rcsb pdb:2Y0A|rcsb pdb:2Y4P|rcsb pdb:2Y4V|rcsb pdb:2YAK|rcsb pdb:3DFC|rcsb pdb:3DGK|rcsb pdb:3EH9|rcsb pdb:3EHA|rcsb pdb:3F5G|rcsb pdb:3F5U|rcsb pdb:3GU4|rcsb pdb:3GU5|rcsb pdb:3GU6|rcsb pdb:3GU7|rcsb pdb:3GU8|rcsb pdb:3GUB|rcsb pdb:3ZXT|rcsb pdb:4B4L|rcsb pdb:4PF4|rcsb pdb:4TL0|rcsb pdb:4TXC|rcsb pdb:4UV0|rcsb pdb:4YO4|rcsb pdb:4YPD|rcsb pdb:5AUT|rcsb pdb:5AUU|rcsb pdb:5AUV|rcsb pdb:5AUW|rcsb pdb:5AUX|rcsb pdb:5AUY|rcsb pdb:5AUZ|rcsb pdb:5AV0|rcsb pdb:5AV1|rcsb pdb:5AV2|rcsb pdb:5AV3|rcsb pdb:5AV4|rcsb pdb:6AAR|rcsb pdb:6FHA|rcsb pdb:6FHB|rcsb pdb:6QN4|rcsb pdb:6GY5|rcsb pdb:6IN4|rcsb pdb:6QMO|refseq:NP_001275658.1|refseq:NP_001275659.1|refseq:NP_001275660.1|rcsb pdb:7CCW|rcsb pdb:7CCV|rcsb pdb:7CCU|reactome:R-HSA-418889	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	-	-	-	figure legend:1 A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/03/26	2014/10/16	rogid:GCxGiQSqtI+M2uqNXe9F4AN1x909606	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	intact-crc:FF4D6FEC0A61366E|rigid:yUNFNCGKS+XqxQ91LmPG/QirAjg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75340	uniprotkb:P53355	intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933	intact:EBI-358616|uniprotkb:Q6ZRZ3|uniprotkb:Q68CP8|uniprotkb:B7ZLD2|uniprotkb:Q1W5W0|ensembl:ENSP00000350785|ensembl:ENSP00000386135|ensembl:ENSP00000417076|ensembl:ENSP00000484267|uniprotkb:Q9BTL8|uniprotkb:Q14CQ7|uniprotkb:B7ZLE7	psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym)	psi-mi:dapk1_human(display_long)|uniprotkb:DAPK1(gene name)|psi-mi:DAPK1(display_short)|uniprotkb:DAPK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2005)	pubmed:16132846|imex:IM-20026	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1748897|imex:IM-20026-3	author score:PREY gene NM_004938	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N	ensembl:ENST00000358077(transcript)|ensembl:ENST00000408954(transcript)|ensembl:ENST00000472284(transcript)|ensembl:ENST00000622514(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|ensembl:ENSG00000196730(gene)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020676|interpro:IPR020683|interpro:IPR020859|interpro:IPR027417|interpro:IPR036770|mint:P53355|rcsb pdb:1IG1|rcsb pdb:1JKK|refseq:NP_004929.2|rcsb pdb:1JKL|rcsb pdb:1JKS|rcsb pdb:1JKT|rcsb pdb:1P4F|rcsb pdb:1WVW|rcsb pdb:1WVY|rcsb pdb:1YR5|rcsb pdb:2W4J|rcsb pdb:2W4K|rcsb pdb:2X0G|rcsb pdb:2XUU|rcsb pdb:2XZS|rcsb pdb:1WVX|rcsb pdb:2Y0A|rcsb pdb:2Y4P|rcsb pdb:2Y4V|rcsb pdb:2YAK|rcsb pdb:3DFC|rcsb pdb:3DGK|rcsb pdb:3EH9|rcsb pdb:3EHA|rcsb pdb:3F5G|rcsb pdb:3F5U|rcsb pdb:3GU4|rcsb pdb:3GU5|rcsb pdb:3GU6|rcsb pdb:3GU7|rcsb pdb:3GU8|rcsb pdb:3GUB|rcsb pdb:3ZXT|rcsb pdb:4B4L|rcsb pdb:4PF4|rcsb pdb:4TL0|rcsb pdb:4TXC|rcsb pdb:4UV0|rcsb pdb:4YO4|rcsb pdb:4YPD|rcsb pdb:5AUT|rcsb pdb:5AUU|rcsb pdb:5AUV|rcsb pdb:5AUW|rcsb pdb:5AUX|rcsb pdb:5AUY|rcsb pdb:5AUZ|rcsb pdb:5AV0|rcsb pdb:5AV1|rcsb pdb:5AV2|rcsb pdb:5AV3|rcsb pdb:5AV4|rcsb pdb:6AAR|rcsb pdb:6FHA|rcsb pdb:6FHB|rcsb pdb:6QN4|rcsb pdb:6GY5|rcsb pdb:6IN4|rcsb pdb:6QMO|refseq:NP_001275658.1|refseq:NP_001275659.1|refseq:NP_001275660.1|rcsb pdb:7CCW|rcsb pdb:7CCV|rcsb pdb:7CCU|reactome:R-HSA-418889	-	-	-	figure legend:1 B|delivery method:O75340; P53355 transfection|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skov_3)|taxid:9606(Homo sapiens ovarian adenocarcinoma cell line)	-	2008/03/26	2014/10/16	rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606	rogid:GCxGiQSqtI+M2uqNXe9F4AN1x909606	intact-crc:2B9A0965FA955E77|rigid:yUNFNCGKS+XqxQ91LmPG/QirAjg	false	green fluorescent protein tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)