#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14599	uniprotkb:P34082	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027600|imex:IM-20157-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. 1H|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-body_muscle)|taxid:7227(Drosophila melanogaster body wall muscle)	-	2008/11/04	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227	intact-crc:7E130181134FC7F7|rigid:8iilpLKnhyZMAZjOVndm5ikQtfU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GQQ6	uniprotkb:P34082	intact:EBI-2027617	intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633	psi-mi:q9gqq6_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:CG5675(orf name)	psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027632|imex:IM-20157-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0026313|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. 7A|comment:"An appl construct lacking the x11l binding domain (coordinates not given) is not pulled down in this complex."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-body_muscle)|taxid:7227(Drosophila melanogaster body wall muscle)	-	2008/11/04	2014/10/16	rogid:NaO9aPUer/LLNFFjsP8ACKUgP+E7227	rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227	intact-crc:198B9810342D97D2|rigid:x3kN1yslkZOL0C7LDzlxcadyrJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GQQ6	uniprotkb:P14599	intact:EBI-2027617	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	psi-mi:q9gqq6_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:CG5675(orf name)	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027632|imex:IM-20157-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0026313|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	-	-	-	figure legend:Fig. 7A|comment:"An appl construct lacking the x11l binding domain (coordinates not given) is not pulled down in this complex."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-body_muscle)|taxid:7227(Drosophila melanogaster body wall muscle)	-	2008/11/04	2014/10/16	rogid:NaO9aPUer/LLNFFjsP8ACKUgP+E7227	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	intact-crc:198B9810342D97D2|rigid:x3kN1yslkZOL0C7LDzlxcadyrJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P34082	uniprotkb:Q9GQQ6	intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633	intact:EBI-2027617	psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name)	psi-mi:q9gqq6_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:CG5675(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027638|imex:IM-20157-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179	flybase:FBgn0026313|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	-	-	-	figure legend:Fig. 7A|comment:Interaction occurs in appl -/- cells.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-body_muscle)|taxid:7227(Drosophila melanogaster body wall muscle)	-	2008/11/04	2014/10/16	rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227	rogid:NaO9aPUer/LLNFFjsP8ACKUgP+E7227	intact-crc:0BB127527B6A36F1|rigid:vHRBmrRCoVz/AXqgpw9pY1U/r5U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14599	uniprotkb:Q9GQQ6	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-2027617	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:q9gqq6_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:CG5675(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027788|imex:IM-20157-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	flybase:FBgn0026313|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	-	-	-	figure legend:Fig. 7B|caution:The coordinates of the PTB domain of P14599  are not given in the paper so have been inferred from the UniProtKB entry for this protein.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-body_muscle)|taxid:7227(Drosophila melanogaster body wall muscle)	-	2008/11/04	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:NaO9aPUer/LLNFFjsP8ACKUgP+E7227	intact-crc:2DD0327BA44B7B17|rigid:8DsO4873eI2h8XR60Hlx/9PtJ9c	false	necessary binding region:?-?(IPR006020)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14599	uniprotkb:P34082	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027817|imex:IM-20157-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. 7C|delivery method:Q9GQQ6; P34082 transfection|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2008/11/04	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227	intact-crc:40210A2256DCBD30|rigid:x3kN1yslkZOL0C7LDzlxcadyrJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14599	uniprotkb:Q9GQQ6	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-2027617	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:q9gqq6_drome(display_long)|uniprotkb:X11L(gene name)|psi-mi:X11L(display_short)|uniprotkb:CG5675(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027817|imex:IM-20157-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	flybase:FBgn0026313|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0043197"(dendritic spine)|go:"GO:0048749"(compound eye development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034	-	-	-	figure legend:Fig. 7C|delivery method:Q9GQQ6; P34082 transfection|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2008/11/04	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:NaO9aPUer/LLNFFjsP8ACKUgP+E7227	intact-crc:40210A2256DCBD30|rigid:x3kN1yslkZOL0C7LDzlxcadyrJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14599	uniprotkb:P34082	intact:EBI-74135|uniprotkb:Q9TVV0|uniprotkb:Q9U4H3|uniprotkb:Q9W5F1|ensemblmetazoa:FBpp0070104	intact:EBI-868243|uniprotkb:P34083|uniprotkb:Q8IRS5|uniprotkb:Q9W4M6|uniprotkb:Q6IDE4|ensemblmetazoa:FBpp0070633	psi-mi:a4_drome(display_long)|uniprotkb:Appl(gene name)|psi-mi:Appl(display_short)|uniprotkb:CG7727(orf name)	psi-mi:fas2_drome(display_long)|uniprotkb:Fasciclin II(gene name synonym)|uniprotkb:Fas2(gene name)|psi-mi:Fas2(display_short)|uniprotkb:CG3665(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ashley et al. (2005)	pubmed:15976083|imex:IM-20157	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2027824|imex:IM-20157-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476626.2|flybase:FBgn0000108|ensemblmetazoa:FBgn0000108(gene)|ensemblmetazoa:FBtr0070109(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048678"(response to axon injury)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|reactome:R-DME-114608|reactome:R-DME-3000178|reactome:R-DME-381426|reactome:R-DME-416476|reactome:R-DME-8957275|reactome:R-DME-9609523	refseq:NP_726911.1|refseq:NP_726912.1|flybase:FBgn0000635|refseq:NP_525066.1|ensemblmetazoa:FBgn0000635(gene)|ensemblmetazoa:FBtr0070665(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008355"(olfactory learning)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016319"(mushroom body development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035158"(regulation of tube diameter, open tracheal system)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072499"(photoreceptor cell axon guidance)|go:"GO:0072553"(terminal button organization)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904800"(negative regulation of neuron remodeling)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Fig. 7C|delivery method:P34082 transfection|comment:Endogenous x11i removed by siRNA treatment.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2008/11/04	2014/10/16	rogid:xK4csyR7K1DKwXB1+c708E6uWx87227	rogid:QW5g1dqazQzsvEKXYHT1dPOJNjU7227	intact-crc:537361870467A61B|rigid:8iilpLKnhyZMAZjOVndm5ikQtfU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)