#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q46925 uniprotkb:P0AGF2 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 intact:EBI-1130454|uniprotkb:Q2MA23|uniprotkb:Q46926|ensemblbacteria:AAC75853|ensemblbacteria:BAE76883 psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:csde_ecoli(display_long)|uniprotkb:csdE(gene name)|psi-mi:csdE(display_short)|uniprotkb:ygdK(gene name synonym)|uniprotkb:JW2782(locus name)|uniprotkb:b2811(locus name) psi-mi:"MI:0018"(two hybrid) Loiseau et al. (2005) pubmed:15901727|imex:IM-20134 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014156|imex:IM-20134-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N refseq:WP_000184261.1|ensemblbacteria:AAC75853(transcript)|ensemblbacteria:b2811(gene)|ensemblbacteria:BAE76883(gene)|ensemblbacteria:BAE76883(transcript)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR003808(Fe-S metabolism associated SufE)|interpro:IPR017763(Cysteine desulphurase, sulphur acceptor subunit CsdE)|rcsb pdb:1NI7|rcsb pdb:5EEP|rcsb pdb:5FT8|rcsb pdb:5NQ6|refseq:NP_417291.1|dip:DIP-12143N - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/17 2014/10/16 rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 rogid:oGw6kn/cDv3rgBJpnMZd6JmpGNM83333 intact-crc:C0C8D94F6254A0AA|rigid:PD/fqnYOgPnU9RIKyLNmNmQUrFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46925 uniprotkb:P0AGF2 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 intact:EBI-1130454|uniprotkb:Q2MA23|uniprotkb:Q46926|ensemblbacteria:AAC75853|ensemblbacteria:BAE76883 psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:csde_ecoli(display_long)|uniprotkb:csdE(gene name)|psi-mi:csdE(display_short)|uniprotkb:ygdK(gene name synonym)|uniprotkb:JW2782(locus name)|uniprotkb:b2811(locus name) psi-mi:"MI:0018"(two hybrid) Loiseau et al. (2005) pubmed:15901727|imex:IM-20134 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014160|imex:IM-20134-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N refseq:WP_000184261.1|ensemblbacteria:AAC75853(transcript)|ensemblbacteria:b2811(gene)|ensemblbacteria:BAE76883(gene)|ensemblbacteria:BAE76883(transcript)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR003808(Fe-S metabolism associated SufE)|interpro:IPR017763(Cysteine desulphurase, sulphur acceptor subunit CsdE)|rcsb pdb:1NI7|rcsb pdb:5EEP|rcsb pdb:5FT8|rcsb pdb:5NQ6|refseq:NP_417291.1|dip:DIP-12143N - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/17 2014/10/16 rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 rogid:oGw6kn/cDv3rgBJpnMZd6JmpGNM83333 intact-crc:ED26D63B0A144797|rigid:PD/fqnYOgPnU9RIKyLNmNmQUrFM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46925 uniprotkb:Q46925 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:"MI:0018"(two hybrid) Loiseau et al. (2005) pubmed:15901727|imex:IM-20134 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2015937|imex:IM-20134-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N - - - figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/10/17 2014/10/16 rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 intact-crc:179876A7EC361293|rigid:5/YQkR6wS1l+4cWCraSHLfe/UUA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q46925 uniprotkb:P0AGF2 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 intact:EBI-1130454|uniprotkb:Q2MA23|uniprotkb:Q46926|ensemblbacteria:AAC75853|ensemblbacteria:BAE76883 psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:csde_ecoli(display_long)|uniprotkb:csdE(gene name)|psi-mi:csdE(display_short)|uniprotkb:ygdK(gene name synonym)|uniprotkb:JW2782(locus name)|uniprotkb:b2811(locus name) psi-mi:"MI:0415"(enzymatic study) Loiseau et al. (2005) pubmed:15901727|imex:IM-20134 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014171|imex:IM-20134-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0840"(stimulator) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N refseq:WP_000184261.1|ensemblbacteria:AAC75853(transcript)|ensemblbacteria:b2811(gene)|ensemblbacteria:BAE76883(gene)|ensemblbacteria:BAE76883(transcript)|go:"GO:0061504"(cyclic threonylcarbamoyladenosine biosynthetic process)|go:"GO:0097163"(sulfur carrier activity)|interpro:IPR003808(Fe-S metabolism associated SufE)|interpro:IPR017763(Cysteine desulphurase, sulphur acceptor subunit CsdE)|rcsb pdb:1NI7|rcsb pdb:5EEP|rcsb pdb:5FT8|rcsb pdb:5NQ6|refseq:NP_417291.1|dip:DIP-12143N go:"GO:0031071"(cysteine desulfurase activity) - - figure legend:Fig. 2, Table 3|kinetics:The Km value of CsdA for cysteine varied from 0.14 to 0.54 mM upon the addition of CsdE.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/10/17 2014/10/16 rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 rogid:oGw6kn/cDv3rgBJpnMZd6JmpGNM83333 intact-crc:7791D9FC9D0D2213 false his tag:?-? his tag:?-?|mutation decreasing interaction:61-61 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:15356" uniprotkb:Q46925 intact:EBI-2014180 intact:EBI-545660|uniprotkb:Q2MA24|ensemblbacteria:BAE76882|ensemblbacteria:AAC75852 psi-mi:cysteine(display_short)|psi-mi:"CHEBI:15356"(display_long) psi-mi:csda_ecoli(display_long)|uniprotkb:Cysteine sulfinate desulfinase(gene name synonym)|uniprotkb:Selenocysteine lyase(gene name synonym)|uniprotkb:csdA(gene name)|psi-mi:csdA(display_short)|uniprotkb:b2810(locus name)|uniprotkb:ygdJ(gene name synonym)|uniprotkb:JW2781(locus name) psi-mi:"MI:0415"(enzymatic study) Loiseau et al. (2005) pubmed:15901727|imex:IM-20134 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2014171|imex:IM-20134-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_417290.1|refseq:WP_001300698.1|ensemblbacteria:BAE76882(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0009000"(selenocysteine lyase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016783"(sulfurtransferase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010970(Cysteine desulphurase, SufS)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|interpro:IPR022471|ensemblbacteria:AAC75852(transcript)|ensemblbacteria:b2810(gene)|ensemblbacteria:BAE76882(gene)|rcsb pdb:4LW2|rcsb pdb:4LW4|rcsb pdb:5FT4|rcsb pdb:5FT5|rcsb pdb:5FT6|rcsb pdb:5FT8|dip:DIP-9323N go:"GO:0031071"(cysteine desulfurase activity) - - figure legend:Fig. 2, Table 3|kinetics:The Km value of CsdA for cysteine varied from 0.14 to 0.54 mM upon the addition of CsdE.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/10/17 2014/10/16 - rogid:DcnHJFxMg10ZAuuFcv0BDeeZcXA83333 intact-crc:7791D9FC9D0D2213 false - his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)