#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60838 uniprotkb:Q80Z96 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750856|imex:IM-19073-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/04/08 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:2D8F8E33F3C81340|rigid:AYkOkoG7fw7C6r5TA1JuCGR4QOY false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q80Z96 uniprotkb:Q60838 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750861|imex:IM-19073-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/04/08 2014/10/16 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 intact-crc:EC1D4D57693E8327|rigid:AYkOkoG7fw7C6r5TA1JuCGR4QOY false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60838 uniprotkb:Q91ZD4 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750866|imex:IM-19073-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2008/04/08 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:17805D20959AC2E5|rigid:jx1iU9MN+ayPpSgFPYOapTqvTr0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51141 uniprotkb:Q80Z96 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750717|imex:IM-19073-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:2|comment:Independent deletion of DIX and DEP regions resulted in loss of interaction. This lead the authors to conclude that PDZ domain is involved in the interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:2350D1BC276D287F|rigid:gXq9dFxnZLkU6e3moM7xc7+RFT8 false sufficient binding region:1-395(IPR001478) sufficient binding region:251-526 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q60838 uniprotkb:Q80Z96 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750726|imex:IM-19073-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:462E7EF878FE784B|rigid:AYkOkoG7fw7C6r5TA1JuCGR4QOY false sufficient binding region:1-418 sufficient binding region:251-526 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61062 uniprotkb:Q80Z96 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750735|imex:IM-19073-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:B651BFA83DC4E5DC|rigid:LUiWRWYx3ngdR8qm6fEMT2NMy8M false sufficient binding region:1-395 sufficient binding region:251-526 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61062 uniprotkb:Q91ZD4 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750761|imex:IM-19073-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:088B37FA380DC581|rigid:1JxAdZi8Y19g+IUzuu5Nd6eyVFY false sufficient binding region:1-395 sufficient binding region:238-521 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91ZD4 uniprotkb:Q60838 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750770|imex:IM-19073-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 intact-crc:F8F4F6AA7D375816|rigid:jx1iU9MN+ayPpSgFPYOapTqvTr0 false sufficient binding region:238-521 sufficient binding region:1-418 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51141 uniprotkb:Q91ZD4 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750779|imex:IM-19073-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:2|comment:Independent deletions of the DIX and DEP did not interact with VANGL2 which lead the authors to conclude that PDZ domain is required for this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/04/08 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:2DFDF55CE418EA6E|rigid:wrsofcqu5iIWs4oxJETI3n5+9sk false sufficient binding region:1-395(IPR001158) sufficient binding region:238-521 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51141 uniprotkb:Q91ZD4 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750794|imex:IM-19073-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:FFCE541129B4CB6D|rigid:wrsofcqu5iIWs4oxJETI3n5+9sk false myc tag:?-? sufficient binding region:238-521|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51141 uniprotkb:Q80Z96 intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750805|imex:IM-19073-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton) refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:m61iD63WqE333GDlyLU6Mlnq50o10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:0EC5E3844BA7CF26|rigid:gXq9dFxnZLkU6e3moM7xc7+RFT8 false myc tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:251-526 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61062 uniprotkb:Q91ZD4 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750812|imex:IM-19073-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:5381889004781E39|rigid:1JxAdZi8Y19g+IUzuu5Nd6eyVFY false ha tag:?-? glutathione s tranferase tag:?-?|sufficient binding region:238-521 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q61062 uniprotkb:Q80Z96 intact:EBI-1538450|uniprotkb:G5E820|ensembl:ENSMUSP00000003318 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl3_mouse(display_long)|uniprotkb:Dvl3(gene name)|psi-mi:Dvl3(display_short)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750823|imex:IM-19073-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031915.2|ensembl:ENSMUSG00000003233(gene)|ensembl:ENSMUST00000003318(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220 refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:+l0INmdRADXIgkikNBGmdG3UfiI10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:ADC96A413192E1B7|rigid:LUiWRWYx3ngdR8qm6fEMT2NMy8M false ha tag:?-? sufficient binding region:251-526|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60838 uniprotkb:Q91ZD4 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-1750744|uniprotkb:Q923Z8|ensembl:ENSMUSP00000027837|ensembl:ENSMUSP00000106894 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:vang2_mouse(display_long)|uniprotkb:Vangl2(gene name)|psi-mi:Vangl2(display_short)|uniprotkb:Lpp1(gene name synonym)|uniprotkb:Ltap(gene name synonym)|uniprotkb:Van Gogh-like protein 2(gene name synonym)|uniprotkb:Loop-tail-associated protein(gene name synonym)|uniprotkb:Loop-tail protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750832|imex:IM-19073-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N refseq:NP_277044.1|refseq:XP_006497114.1|refseq:XP_006497115.1|refseq:XP_006497116.1|refseq:XP_006497117.1|refseq:XP_017168497.1|ensembl:ENSMUSG00000026556(gene)|ensembl:ENSMUST00000027837(transcript)|ensembl:ENSMUST00000111263(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0001947"(heart looping)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032835"(glomerulus development)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035787"(cell migration involved in kidney development)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036514"(dopaminergic neuron axon guidance)|go:"GO:0036515"(serotonergic neuron axon guidance)|go:"GO:0042060"(wound healing)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060187"(cell pole)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061346"(planar cell polarity pathway involved in heart morphogenesis)|go:"GO:0071944"(cell periphery)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090177"(establishment of planar polarity involved in neural tube closure)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090651"(apical cytoplasm)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009539(Strabismus)|mint:Q91ZD4|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:+krVIc5MKw2MU7mV/4VtLy+qCRo10090 intact-crc:083038932827204A|rigid:jx1iU9MN+ayPpSgFPYOapTqvTr0 false ha tag:?-? sufficient binding region:238-521|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60838 uniprotkb:Q80Z96 intact:EBI-641940|uniprotkb:Q7TN14|ensembl:ENSMUSP00000099635|ensembl:ENSMUSP00000140073|ensembl:ENSMUSP00000019362 intact:EBI-1750708|uniprotkb:Q8QZT3|uniprotkb:B2RRP5|ensembl:ENSMUSP00000029453 psi-mi:dvl2_mouse(display_long)|uniprotkb:Dvl2(gene name)|psi-mi:Dvl2(display_short)|uniprotkb:DSH homolog 2(gene name synonym) psi-mi:vang1_mouse(display_long)|uniprotkb:Vangl1(gene name)|psi-mi:Vangl1(display_short)|uniprotkb:Lpp2(gene name synonym)|uniprotkb:Van Gogh-like protein 1(gene name synonym)|uniprotkb:Loop-tail protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Torban et al. (2004) pubmed:15456783|imex:IM-19073 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1750843|imex:IM-19073-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031914.3|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q60838|rcsb pdb:3ML6|rcsb pdb:6VCC|reactome:R-MMU-201688|reactome:R-MMU-2028269|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5099900|reactome:R-MMU-5663220|reactome:R-MMU-8856825|reactome:R-MMU-8856828|ensembl:ENSMUST00000019362(transcript)|ensembl:ENSMUST00000102575(transcript)|ensembl:ENSMUST00000190940(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035282"(segmentation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060029"(convergent extension involved in organogenesis)|ensembl:ENSMUSG00000020888(gene)|dip:DIP-29399N refseq:NP_808213.2|ensembl:ENSMUSG00000027860(gene)|ensembl:ENSMUST00000029453(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043473"(pigmentation)|interpro:IPR009539(Strabismus)|mint:Q80Z96|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-9035034|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273 - - - figure legend:3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/04/08 2014/10/16 rogid:bFjXy0cGGbY8YE60qW3+0NLpqNs10090 rogid:bokoX4rdUNELRjNfit5xoSJyL4s10090 intact-crc:F678DA421DCDDFC4|rigid:AYkOkoG7fw7C6r5TA1JuCGR4QOY false ha tag:?-? sufficient binding region:251-526|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)