#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16591 uniprotkb:O42486 intact:EBI-1380661|uniprotkb:B4DSQ2|uniprotkb:B2RCR4|uniprotkb:H2FLB8|ensembl:ENSP00000281092 intact:EBI-972394 psi-mi:fer_human(display_long)|uniprotkb:Feline encephalitis virus-related kinase FER(gene name synonym)|uniprotkb:Fujinami poultry sarcoma/Feline sarcoma-related protein Fer(gene name synonym)|uniprotkb:FER(gene name)|psi-mi:FER(display_short)|uniprotkb:TYK3(gene name synonym)|uniprotkb:Proto-oncogene c-Fer(gene name synonym)|uniprotkb:Tyrosine kinase 3(gene name synonym)|uniprotkb:p94-Fer(gene name synonym) psi-mi:o42486_chick(display_long)|uniprotkb:Bcat(gene name)|psi-mi:Bcat(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7212660|mint:MINT-6764543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005237.2|refseq:XP_016864719.1|refseq:XP_016864720.1|refseq:NP_001294957.1|refseq:NP_001294960.1|refseq:NP_001294967.1|refseq:XP_011541573.1|ensembl:ENSG00000151422(gene)|ensembl:ENST00000281092(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036119"(response to platelet-derived growth factor)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050904"(diapedesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR028539|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR037452|mint:P16591|rcsb pdb:2KK6|rcsb pdb:6KC4|reactome:R-HSA-1433557|mint:MINT-6764544(identity)|uniprotkb:P16591(P16591) go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|refseq:NP_990412.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|mint:O42486|mint:MINT-6764553(identity)|uniprotkb:O42486(O42486) - - - figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/18 2014/10/16 rogid:De5RYVRGihPHGxaflmxR8W9jC8M9606 rogid:k+sIhZAa8voPXrmI8KjWdny63XY9031 intact-crc:904AC169443037BA|rigid:3ECnZlt15N4TsfsdiBtS2QICgZQ false binding-associated region:305-380(MINT-6764546)|his tag:?-?(MINT-6764551) binding-associated region:131-156(MINT-6764555)|glutathione s tranferase tag:?-?(MINT-6764557) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16591 uniprotkb:O42486 intact:EBI-1380661|uniprotkb:B4DSQ2|uniprotkb:B2RCR4|uniprotkb:H2FLB8|ensembl:ENSP00000281092 intact:EBI-972394 psi-mi:fer_human(display_long)|uniprotkb:Feline encephalitis virus-related kinase FER(gene name synonym)|uniprotkb:Fujinami poultry sarcoma/Feline sarcoma-related protein Fer(gene name synonym)|uniprotkb:FER(gene name)|psi-mi:FER(display_short)|uniprotkb:TYK3(gene name synonym)|uniprotkb:Proto-oncogene c-Fer(gene name synonym)|uniprotkb:Tyrosine kinase 3(gene name synonym)|uniprotkb:p94-Fer(gene name synonym) psi-mi:o42486_chick(display_long)|uniprotkb:Bcat(gene name)|psi-mi:Bcat(display_short) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7212703|mint:MINT-6792840 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005237.2|refseq:XP_016864719.1|refseq:XP_016864720.1|refseq:NP_001294957.1|refseq:NP_001294960.1|refseq:NP_001294967.1|refseq:XP_011541573.1|ensembl:ENSG00000151422(gene)|ensembl:ENST00000281092(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036119"(response to platelet-derived growth factor)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050904"(diapedesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR028539|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR037452|mint:P16591|rcsb pdb:2KK6|rcsb pdb:6KC4|reactome:R-HSA-1433557|mint:MINT-6792849(identity)|uniprotkb:P16591(P16591) go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|refseq:NP_990412.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|mint:O42486|mint:MINT-6792842(identity)|uniprotkb:O42486(O42486) - - - figure legend:F1|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/18 2014/10/16 rogid:De5RYVRGihPHGxaflmxR8W9jC8M9606 rogid:k+sIhZAa8voPXrmI8KjWdny63XY9031 intact-crc:8D3C0A1F9CB8532B|rigid:3ECnZlt15N4TsfsdiBtS2QICgZQ false mutation decreasing interaction:152-152(MINT-6792852)|binding-associated region:331-360(MINT-6792854)|glutathione s tranferase tag:?-?(MINT-6792850) tag:?-?(MINT-6792843) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13016 uniprotkb:P16591 intact:EBI-6938259|uniprotkb:Q90704|intact:UNK-6008604 intact:EBI-1380661|uniprotkb:B4DSQ2|uniprotkb:B2RCR4|uniprotkb:H2FLB8|ensembl:ENSP00000281092 psi-mi:ptn1_chick(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)|uniprotkb:CPTP1(gene name synonym) psi-mi:fer_human(display_long)|uniprotkb:Feline encephalitis virus-related kinase FER(gene name synonym)|uniprotkb:Fujinami poultry sarcoma/Feline sarcoma-related protein Fer(gene name synonym)|uniprotkb:FER(gene name)|psi-mi:FER(display_short)|uniprotkb:TYK3(gene name synonym)|uniprotkb:Proto-oncogene c-Fer(gene name synonym)|uniprotkb:Tyrosine kinase 3(gene name synonym)|uniprotkb:p94-Fer(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7212744|mint:MINT-6764561 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_990206.1|interpro:IPR029021|mint:O13016|mint:MINT-6764570(identity)|uniprotkb:O13016(O13016) refseq:NP_005237.2|refseq:XP_016864719.1|refseq:XP_016864720.1|refseq:NP_001294957.1|refseq:NP_001294960.1|refseq:NP_001294967.1|refseq:XP_011541573.1|ensembl:ENSG00000151422(gene)|ensembl:ENST00000281092(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036119"(response to platelet-derived growth factor)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050904"(diapedesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR028539|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR037452|mint:P16591|rcsb pdb:2KK6|rcsb pdb:6KC4|reactome:R-HSA-1433557|mint:MINT-6764577(identity)|uniprotkb:P16591(P16591) - function:May play an important role in CKII- and p60c-src-induced signal transduction cascades|comment:mint|comment:homomint - figure legend:F6B|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:e98/zD3vaTow6yAypbMRX7m5/a09031 rogid:De5RYVRGihPHGxaflmxR8W9jC8M9606 intact-crc:9E9F93E2A37C0A5D|rigid:ZRNsZ8NKSn5TB00W6WiswcBsX5g false mutation disrupting interaction:152-152(MINT-6764572)|mutation disrupting interaction:215-215(MINT-6792901)|glutathione s tranferase tag:?-?(MINT-6764575) mutation disrupting interaction:743-743(MINT-6792895) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10288 uniprotkb:P16591 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-1380661|uniprotkb:B4DSQ2|uniprotkb:B2RCR4|uniprotkb:H2FLB8|ensembl:ENSP00000281092 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:fer_human(display_long)|uniprotkb:Feline encephalitis virus-related kinase FER(gene name synonym)|uniprotkb:Fujinami poultry sarcoma/Feline sarcoma-related protein Fer(gene name synonym)|uniprotkb:FER(gene name)|psi-mi:FER(display_short)|uniprotkb:TYK3(gene name synonym)|uniprotkb:Proto-oncogene c-Fer(gene name synonym)|uniprotkb:Tyrosine kinase 3(gene name synonym)|uniprotkb:p94-Fer(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7212795|mint:MINT-6792867 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N|mint:MINT-6792885(identity)|uniprotkb:P10288(P10288) refseq:NP_005237.2|refseq:XP_016864719.1|refseq:XP_016864720.1|refseq:NP_001294957.1|refseq:NP_001294960.1|refseq:NP_001294967.1|refseq:XP_011541573.1|ensembl:ENSG00000151422(gene)|ensembl:ENST00000281092(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036119"(response to platelet-derived growth factor)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050904"(diapedesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR028539|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR037452|mint:P16591|rcsb pdb:2KK6|rcsb pdb:6KC4|reactome:R-HSA-1433557|mint:MINT-6792869(identity)|uniprotkb:P16591(P16591) - - - figure legend:F5|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:De5RYVRGihPHGxaflmxR8W9jC8M9606 intact-crc:DD6B649A66C1F3AB|rigid:NafMq0ZK4TR4KFbUXsKp73I9USU false - glutathione s tranferase tag:?-?(MINT-6792870) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10288 uniprotkb:P16591 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-1380661|uniprotkb:B4DSQ2|uniprotkb:B2RCR4|uniprotkb:H2FLB8|ensembl:ENSP00000281092 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:fer_human(display_long)|uniprotkb:Feline encephalitis virus-related kinase FER(gene name synonym)|uniprotkb:Fujinami poultry sarcoma/Feline sarcoma-related protein Fer(gene name synonym)|uniprotkb:FER(gene name)|psi-mi:FER(display_short)|uniprotkb:TYK3(gene name synonym)|uniprotkb:Proto-oncogene c-Fer(gene name synonym)|uniprotkb:Tyrosine kinase 3(gene name synonym)|uniprotkb:p94-Fer(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7212795|mint:MINT-6792867 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N|mint:MINT-6792885(identity)|uniprotkb:P10288(P10288) refseq:NP_005237.2|refseq:XP_016864719.1|refseq:XP_016864720.1|refseq:NP_001294957.1|refseq:NP_001294960.1|refseq:NP_001294967.1|refseq:XP_011541573.1|ensembl:ENSG00000151422(gene)|ensembl:ENST00000281092(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035426"(extracellular matrix-cell signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0036119"(response to platelet-derived growth factor)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038109"(Kit signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050904"(diapedesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016250(Tyrosine-protein kinase, Fes/Fps)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027267|interpro:IPR028539|interpro:IPR031160|interpro:IPR035849|interpro:IPR036860|interpro:IPR037452|mint:P16591|rcsb pdb:2KK6|rcsb pdb:6KC4|reactome:R-HSA-1433557|mint:MINT-6792879(identity)|uniprotkb:P16591(P16591) - - - figure legend:F5|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:De5RYVRGihPHGxaflmxR8W9jC8M9606 intact-crc:DD6B649A66C1F3AB|rigid:NafMq0ZK4TR4KFbUXsKp73I9USU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10288 uniprotkb:O42486 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-972394 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:o42486_chick(display_long)|uniprotkb:Bcat(gene name)|psi-mi:Bcat(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7212795|mint:MINT-6792867 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N|mint:MINT-6792885(identity)|uniprotkb:P10288(P10288) go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|refseq:NP_990412.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|mint:O42486|mint:MINT-6792881(identity)|uniprotkb:O42486(O42486) - - - figure legend:F5|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:k+sIhZAa8voPXrmI8KjWdny63XY9031 intact-crc:DD6B649A66C1F3AB|rigid:NafMq0ZK4TR4KFbUXsKp73I9USU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10288 uniprotkb:O13016 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-6938259|uniprotkb:Q90704|intact:UNK-6008604 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:ptn1_chick(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)|uniprotkb:CPTP1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7212795|mint:MINT-6792867 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N|mint:MINT-6792885(identity)|uniprotkb:P10288(P10288) go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_990206.1|interpro:IPR029021|mint:O13016|mint:MINT-6792873(identity)|uniprotkb:O13016(O13016) - - function:May play an important role in CKII- and p60c-src-induced signal transduction cascades|comment:mint|comment:homomint figure legend:F5|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:e98/zD3vaTow6yAypbMRX7m5/a09031 intact-crc:DD6B649A66C1F3AB|rigid:NafMq0ZK4TR4KFbUXsKp73I9USU false - mutation disrupting interaction:152-152(MINT-6792876)|glutathione s tranferase tag:?-?(MINT-6792874) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10288 uniprotkb:O13016 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-6938259|uniprotkb:Q90704|intact:UNK-6008604 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:ptn1_chick(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)|uniprotkb:CPTP1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Xu et al. (2004) pubmed:15226396|mint:MINT-6671732 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7212795|mint:MINT-6792867 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N|mint:MINT-6792885(identity)|uniprotkb:P10288(P10288) go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|refseq:NP_990206.1|interpro:IPR029021|mint:O13016|mint:MINT-6792883(identity)|uniprotkb:O13016(O13016) - - function:May play an important role in CKII- and p60c-src-induced signal transduction cascades|comment:mint|comment:homomint figure legend:F5|comment:homomint|comment:mint taxid:9031(chick-retina)|taxid:9031(Gallus gallus) - 2008/09/18 2014/10/16 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:e98/zD3vaTow6yAypbMRX7m5/a09031 intact-crc:DD6B649A66C1F3AB|rigid:NafMq0ZK4TR4KFbUXsKp73I9USU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)