#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q54QQ1	uniprotkb:P18613	intact:EBI-1807983|uniprotkb:Q6H9K1|ensemblprotists:EAL65616	intact:EBI-1808055|uniprotkb:Q54EV9|ensemblprotists:EAL61602	psi-mi:phg2_dicdi(display_long)|uniprotkb:phg2(gene name)|psi-mi:phg2(display_short)|uniprotkb:DDB_G0283699(orf name)	psi-mi:rapa_dicdi(display_long)|uniprotkb:rapA(gene name)|psi-mi:rapA(display_short)|uniprotkb:rap1(gene name synonym)|uniprotkb:DDB_G0291237(orf name)|uniprotkb:Ras-related protein rap-1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gebbie et al. (2004)	pubmed:15194808|imex:IM-18868	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1808104|imex:IM-18868-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dictybase:DDB_G0283699|ensemblprotists:DDB_G0283699(gene)|ensemblprotists:EAL65616(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031156"(regulation of sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0048870"(cell motility)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_638972.1	dictybase:DDB_G0291237|ensemblprotists:DDB_G0291237(gene)|ensemblprotists:EAL61602(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0006997"(nucleus organization)|go:"GO:0009409"(response to cold)|go:"GO:0019003"(GDP binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031289"(actin phosphorylation)|go:"GO:0031982"(vesicle)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043520"(regulation of myosin II filament assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060187"(cell pole)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0140220"(pathogen-containing vacuole)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR038851|reactome:R-DDI-354192|reactome:R-DDI-381676|reactome:R-DDI-392517|reactome:R-DDI-6798695|refseq:XP_635131.1|go:"GO:0030587"(sorocarp development)	-	-	-	figure legend:Fig 2B, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/09	2014/10/16	rogid:AtKmdvgkxarUJktZ/u3095lJSo044689	rogid:qSYVh8klciQCxJkVmVB3lifp25w44689	intact-crc:24D641D256FF4443|rigid:5fQfHz43DYMx5n/HTbQq0MhC73U	false	sufficient binding region:594-667	mutation:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15064	uniprotkb:Q54QQ1	intact:EBI-1808115|uniprotkb:Q54BT6|ensemblprotists:EAL60719	intact:EBI-1807983|uniprotkb:Q6H9K1|ensemblprotists:EAL65616	psi-mi:rasg_dicdi(display_long)|uniprotkb:rasG(gene name)|psi-mi:rasG(display_short)|uniprotkb:DDB_G0293434(orf name)	psi-mi:phg2_dicdi(display_long)|uniprotkb:phg2(gene name)|psi-mi:phg2(display_short)|uniprotkb:DDB_G0283699(orf name)	psi-mi:"MI:0018"(two hybrid)	Gebbie et al. (2004)	pubmed:15194808|imex:IM-18868	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1808111|imex:IM-18868-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dictybase:DDB_G0293434|ensemblprotists:DDB_G0293434(gene)|ensemblprotists:EAL60719(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010753"(positive regulation of cGMP-mediated signaling)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019003"(GDP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019954"(asexual reproduction)|go:"GO:0030250"(guanylate cyclase activator activity)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043326"(chemotaxis to folate)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044354"(macropinosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046586"(regulation of calcium-dependent cell-cell adhesion)|go:"GO:0046847"(filopodium assembly)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051591"(response to cAMP)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0140220"(pathogen-containing vacuole)|go:"GO:1901262"(negative regulation of sorocarp spore cell differentiation)|go:"GO:1903666"(positive regulation of asexual reproduction)|go:"GO:1903669"(positive regulation of chemorepellent activity)|go:"GO:1905169"(regulation of protein localization to phagocytic vesicle)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DDI-1169092|reactome:R-DDI-171007|reactome:R-DDI-5218921|reactome:R-DDI-5621575|reactome:R-DDI-5658442|reactome:R-DDI-5673000|reactome:R-DDI-5673001|reactome:R-DDI-5674135|reactome:R-DDI-5675221|reactome:R-DDI-6798695|reactome:R-DDI-8849471|reactome:R-DDI-9648002|refseq:XP_629133.1	dictybase:DDB_G0283699|ensemblprotists:DDB_G0283699(gene)|ensemblprotists:EAL65616(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031156"(regulation of sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0048870"(cell motility)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_638972.1	-	-	-	figure legend:Fig 2B, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/09	2014/10/16	rogid:lSZXKXh0lVMiHRW0T4sl7RX9yo444689	rogid:AtKmdvgkxarUJktZ/u3095lJSo044689	intact-crc:7AAD0AEEAC3F2F04|rigid:lHrMkk2DqODuz+AlO5JUnj+ov44	false	mutation:12-12	sufficient binding region:594-667	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32254	uniprotkb:Q54QQ1	intact:EBI-1808132|uniprotkb:Q54QW0|ensemblprotists:EAL65646	intact:EBI-1807983|uniprotkb:Q6H9K1|ensemblprotists:EAL65616	psi-mi:rass_dicdi(display_long)|uniprotkb:rasS(gene name)|psi-mi:rasS(display_short)|uniprotkb:DDB_G0283537(orf name)	psi-mi:phg2_dicdi(display_long)|uniprotkb:phg2(gene name)|psi-mi:phg2(display_short)|uniprotkb:DDB_G0283699(orf name)	psi-mi:"MI:0018"(two hybrid)	Gebbie et al. (2004)	pubmed:15194808|imex:IM-18868	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1808128|imex:IM-18868-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dictybase:DDB_G0283537|ensemblprotists:DDB_G0283537(gene)|ensemblprotists:EAL65646(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006907"(pinocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019003"(GDP binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044351"(macropinocytosis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-DDI-1169092|reactome:R-DDI-171007|reactome:R-DDI-5218921|reactome:R-DDI-5621575|reactome:R-DDI-5658442|reactome:R-DDI-5673000|reactome:R-DDI-5673001|reactome:R-DDI-5674135|reactome:R-DDI-5675221|reactome:R-DDI-6798695|reactome:R-DDI-8849471|reactome:R-DDI-9648002|refseq:XP_639024.1	dictybase:DDB_G0283699|ensemblprotists:DDB_G0283699(gene)|ensemblprotists:EAL65616(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031156"(regulation of sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0048870"(cell motility)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_638972.1	-	-	-	figure legend:Fig 2B, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/09/09	2014/10/16	rogid:71GGXjoNFT91jvp0AZZLC7/4AOk44689	rogid:AtKmdvgkxarUJktZ/u3095lJSo044689	intact-crc:2072AE2B2D291775|rigid:zG642YdYGWHlgeOiBPlwiPRDAcQ	false	mutation:12-12	sufficient binding region:594-667	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)