#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41932 uniprotkb:Q10666 intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym) psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lo et al. (2004) pubmed:15066285|imex:IM-19448 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811705|imex:IM-19448-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700 reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 - - - figure legend:Fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo) - 2008/09/15 2014/10/16 rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 intact-crc:C41B1D12C32623A3|rigid:AMvi81w/0kovRa/zPPebf9i1YQ4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q10666 uniprotkb:P41932 intact:EBI-317870|uniprotkb:O45007|ensemblmetazoa:W10C8.2.1 intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3 psi-mi:pop1_caeel(display_long)|uniprotkb:pop-1(gene name)|psi-mi:pop-1(display_short)|uniprotkb:W10C8.2(orf name)|uniprotkb:Posterior pharynx defect protein 1(gene name synonym) psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Lo et al. (2004) pubmed:15066285|imex:IM-19448 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1811768|imex:IM-19448-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-4641265|wormbase:W10C8.2|reactome:R-CEL-8853884|reactome:R-CEL-3769402|refseq:NP_491053.4|ensemblmetazoa:W10C8.2.1(transcript)|ensemblmetazoa:WBGene00004077(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007500"(mesodermal cell fate determination)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010085"(polarity specification of proximal/distal axis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061853"(regulation of neuroblast migration)|go:"GO:2000746"(regulation of defecation rhythm)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|interpro:IPR028782|interpro:IPR036910|rcsb pdb:3C2G|go:"GO:1990907"(beta-catenin-TCF complex)|dip:DIP-25683N|reactome:R-CEL-201722|reactome:R-CEL-4086398|reactome:R-CEL-8951430 refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700 - - - figure legend:Fig 2E|stimulant:Interaction between pop-1 and par-5 may require phosphorylation of pop-1 on serine 118 and serine 127.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2008/09/15 2014/10/16 rogid:kzktFe2ZSDObXvcMQsdR9o90wGI6239 rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239 intact-crc:B9A10A1FFC8747FF|rigid:AMvi81w/0kovRa/zPPebf9i1YQ4 false mutation disrupting interaction:107-107,109-109,118-118,120-120,127-127 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)