#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NS61 uniprotkb:Q9NZV8 intact:EBI-1052975|uniprotkb:Q9HD11|uniprotkb:Q9NS60|uniprotkb:Q9NY10|uniprotkb:Q9NZI1|uniprotkb:Q7Z6F1|uniprotkb:Q96K86|uniprotkb:Q96T41|uniprotkb:Q96T42|uniprotkb:Q96T43|uniprotkb:Q96T44|uniprotkb:Q9H0N4|uniprotkb:Q9HD10|uniprotkb:A6NJE5|uniprotkb:Q3YAC8|uniprotkb:Q3YAC9|uniprotkb:A8MQ75|uniprotkb:Q3YAC6|ensembl:ENSP00000349055 intact:EBI-1646745|uniprotkb:O95012|uniprotkb:O95021|uniprotkb:Q2TBD3|uniprotkb:Q9UBY7|uniprotkb:Q9UN98|uniprotkb:Q9UNH9|ensembl:ENSP00000333496 psi-mi:kcip2_human(display_long)|uniprotkb:Cardiac voltage-gated potassium channel modulatory subunit(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 2(gene name synonym)|uniprotkb:Potassium channel-interacting protein 2(gene name synonym)|uniprotkb:KCNIP2(gene name)|psi-mi:KCNIP2(display_short)|uniprotkb:KCHIP2(gene name synonym) psi-mi:kcnd2_human(display_long)|uniprotkb:KCND2(gene name)|psi-mi:KCND2(display_short)|uniprotkb:KIAA1044(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv4.2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Kim et al. (2004) pubmed:14623880|imex:IM-20015 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1646771|imex:IM-20015-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055406.2|refseq:NP_775283.1|refseq:NP_775284.1|refseq:NP_775285.1|refseq:NP_775286.1|refseq:NP_775287.1|refseq:NP_775289.1|ensembl:ENSG00000120049(gene)|ensembl:ENST00000356640(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0034705"(potassium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045163"(clustering of voltage-gated potassium channels)|go:"GO:0045202"(synapse)|go:"GO:0046923"(ER retention sequence binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1903766"(positive regulation of potassium ion export across plasma membrane)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|reactome:R-HSA-5576894 refseq:NP_036413.1|ensembl:ENSG00000184408(gene)|ensembl:ENST00000331113(transcript)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004055(Potassium channel, voltage dependent, Kv4.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|reactome:R-HSA-1296072|reactome:R-HSA-5576894 - - - figure legend:Fig. 3|delivery method:Q9NZV8 transfection; Q9NS61 transfection|comment:Molar ratio of molecules measured by amino acid analysis, stoichiometry then calculated from the estimated weight of entire complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2008/03/07 2014/10/16 rogid:1QBxTVfJPPxe45IT6nuStlFp0YE9606 rogid:v8IHRYwBvldpx3e1gM58lmmHmjg9606 intact-crc:F704AC23E8EF083F|rigid:kuSYE/LqREQ1iQJ5svGvXRXjCic false - - 4 4 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)