#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BXW9	uniprotkb:O00255	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jin et al. (2003)	pubmed:12874027|imex:IM-18979	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1789693|imex:IM-18979-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE	-	-	-	figure legend:2|delivery method:O00255 transfection|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/09	2014/12/08	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606	intact-crc:08CEECDECB211836|rigid:xzY760vOjQ4a7wEsjTXaGK93Ov4	false	-	flag tag:?-?|sufficient binding region:219-395	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00255	uniprotkb:Q9BXW9	intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jin et al. (2003)	pubmed:12874027|imex:IM-18979	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1789715|imex:IM-18979-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:1D|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/09	2014/12/08	rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	intact-crc:70C81BFD8CFFE2E0|rigid:xzY760vOjQ4a7wEsjTXaGK93Ov4	false	flag tag:?-?	identified peptide:10-22	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O00255	uniprotkb:Q9BXW9	intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym)	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jin et al. (2003)	pubmed:12874027|imex:IM-18979	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2010665|imex:IM-18979-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	-	-	-	figure legend:3|comment:IR irradiation increased the interaction of Men1 with Fancd 2 t- 4 hours after treatment.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2008/07/09	2014/12/08	rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	intact-crc:0FCE93760904B697|rigid:xzY760vOjQ4a7wEsjTXaGK93Ov4	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BXW9	uniprotkb:O00255	intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379	intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530	psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym)	psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jin et al. (2003)	pubmed:12874027|imex:IM-18979	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2010683|imex:IM-18979-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N	refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE	-	-	-	figure legend:1C|sample process:FANCD2 endogenous|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2008/07/09	2014/12/08	rogid:9szrKioB24vbUy47a30DPUQhqkA9606	rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606	intact-crc:7CB6EECD6C119594|rigid:xzY760vOjQ4a7wEsjTXaGK93Ov4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)