#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q91X43	uniprotkb:O08641	intact:EBI-2024543|uniprotkb:O08635|uniprotkb:O35146|uniprotkb:Q8C7I2|ensembl:ENSMUSP00000103291|ensembl:ENSMUSP00000138320|ensembl:ENSMUSP00000158600|ensembl:ENSMUSP00000158775	intact:EBI-2024519|uniprotkb:Q6P7V3|uniprotkb:Q6PDR3|ensembl:ENSMUSP00000020997	psi-mi:sh319_mouse(display_long)|uniprotkb:Sh3d19(gene name)|psi-mi:Sh3d19(display_short)|uniprotkb:Kryn(gene name synonym)	psi-mi:sh3y1_mouse(display_long)|uniprotkb:Sh3yl1(gene name)|psi-mi:Sh3yl1(display_short)	psi-mi:"MI:0018"(two hybrid)	Shimomura et al. (2003)	pubmed:12615363|imex:IM-20142	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2024538|imex:IM-20142-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001075883.2|ensembl:ENSMUSG00000028082(gene)|ensembl:ENSMUST00000107664(transcript)|ensembl:ENSMUST00000182666(transcript)|ensembl:ENSMUST00000238222(transcript)|ensembl:ENSMUST00000238331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-MMU-432722	refseq:NP_001276409.1|refseq:NP_038737.1|ensembl:ENSMUSG00000020669(gene)|ensembl:ENSMUST00000020997(transcript)|interpro:IPR035511|interpro:IPR036028|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1900027"(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/22	2014/10/16	rogid:H9y/y3ClfrgC1SSBI/1pD0CliVs10090	rogid:D/t9mnLnDwPFPX4hBXBKNm5Mn/810090	intact-crc:4C25672428F9B459|rigid:bjT8Ua5pbT2hYoZ2udbdPSj76IE	false	-	binding-associated region:281-340	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O08641	uniprotkb:Q6DFV5	intact:EBI-2024519|uniprotkb:Q6P7V3|uniprotkb:Q6PDR3|ensembl:ENSMUSP00000020997	intact:EBI-2024565|uniprotkb:A1L4L4|uniprotkb:Q8BZZ6|uniprotkb:Q8CHI3|uniprotkb:Q8VDI3|uniprotkb:A2AAU4|ensembl:ENSMUSP00000102357	psi-mi:sh3y1_mouse(display_long)|uniprotkb:Sh3yl1(gene name)|psi-mi:Sh3yl1(display_short)	psi-mi:helz_mouse(display_long)|uniprotkb:Helz(gene name)|psi-mi:Helz(display_short)|uniprotkb:Kiaa0054(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shimomura et al. (2003)	pubmed:12615363|imex:IM-20142	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2024605|imex:IM-20142-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276409.1|refseq:NP_038737.1|ensembl:ENSMUSG00000020669(gene)|ensembl:ENSMUST00000020997(transcript)|interpro:IPR035511|interpro:IPR036028|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1900027"(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643	refseq:NP_938040.1|refseq:XP_006534567.1|refseq:XP_006534568.1|refseq:XP_006534569.1|refseq:XP_006534570.1|ensembl:ENSMUSG00000020721(gene)|ensembl:ENSMUST00000106746(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR027417|interpro:IPR036855|interpro:IPR041677|interpro:IPR041679	-	-	-	figure legend:no figure|caution:The interaction could not be demonstrated by a GST-pull down experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/22	2014/10/16	rogid:D/t9mnLnDwPFPX4hBXBKNm5Mn/810090	rogid:DEMFtw86Nv7VUJf4ukFkMrOj1BE10090	intact-crc:0625D137585068B5|rigid:tJKpm5AkzpHe/RFiXdNXWnGsCKQ	false	binding-associated region:281-340	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O08641	uniprotkb:Q91X43	intact:EBI-2024519|uniprotkb:Q6P7V3|uniprotkb:Q6PDR3|ensembl:ENSMUSP00000020997	intact:EBI-2024543|uniprotkb:O08635|uniprotkb:O35146|uniprotkb:Q8C7I2|ensembl:ENSMUSP00000103291|ensembl:ENSMUSP00000138320|ensembl:ENSMUSP00000158600|ensembl:ENSMUSP00000158775	psi-mi:sh3y1_mouse(display_long)|uniprotkb:Sh3yl1(gene name)|psi-mi:Sh3yl1(display_short)	psi-mi:sh319_mouse(display_long)|uniprotkb:Sh3d19(gene name)|psi-mi:Sh3d19(display_short)|uniprotkb:Kryn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shimomura et al. (2003)	pubmed:12615363|imex:IM-20142	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2024636|imex:IM-20142-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276409.1|refseq:NP_038737.1|ensembl:ENSMUSG00000020669(gene)|ensembl:ENSMUST00000020997(transcript)|interpro:IPR035511|interpro:IPR036028|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1900027"(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643	refseq:NP_001075883.2|ensembl:ENSMUSG00000028082(gene)|ensembl:ENSMUST00000107664(transcript)|ensembl:ENSMUST00000182666(transcript)|ensembl:ENSMUST00000238222(transcript)|ensembl:ENSMUST00000238331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-MMU-432722	-	-	-	figure legend:5A and 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/22	2014/10/16	rogid:D/t9mnLnDwPFPX4hBXBKNm5Mn/810090	rogid:H9y/y3ClfrgC1SSBI/1pD0CliVs10090	intact-crc:034EBB07A6BB476D|rigid:bjT8Ua5pbT2hYoZ2udbdPSj76IE	false	-	glutathione s tranferase tag:?-?|binding-associated region:1-40	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O08641	uniprotkb:Q91X43	intact:EBI-2024519|uniprotkb:Q6P7V3|uniprotkb:Q6PDR3|ensembl:ENSMUSP00000020997	intact:EBI-2024543|uniprotkb:O08635|uniprotkb:O35146|uniprotkb:Q8C7I2|ensembl:ENSMUSP00000103291|ensembl:ENSMUSP00000138320|ensembl:ENSMUSP00000158600|ensembl:ENSMUSP00000158775	psi-mi:sh3y1_mouse(display_long)|uniprotkb:Sh3yl1(gene name)|psi-mi:Sh3yl1(display_short)	psi-mi:sh319_mouse(display_long)|uniprotkb:Sh3d19(gene name)|psi-mi:Sh3d19(display_short)|uniprotkb:Kryn(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shimomura et al. (2003)	pubmed:12615363|imex:IM-20142	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2024646|imex:IM-20142-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276409.1|refseq:NP_038737.1|ensembl:ENSMUSG00000020669(gene)|ensembl:ENSMUST00000020997(transcript)|interpro:IPR035511|interpro:IPR036028|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1900027"(regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643	refseq:NP_001075883.2|ensembl:ENSMUSG00000028082(gene)|ensembl:ENSMUST00000107664(transcript)|ensembl:ENSMUST00000182666(transcript)|ensembl:ENSMUST00000238222(transcript)|ensembl:ENSMUST00000238331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-MMU-432722	-	-	-	figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/22	2014/10/16	rogid:D/t9mnLnDwPFPX4hBXBKNm5Mn/810090	rogid:H9y/y3ClfrgC1SSBI/1pD0CliVs10090	intact-crc:6CD295FB5A116B44|rigid:bjT8Ua5pbT2hYoZ2udbdPSj76IE	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)