#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q62968 uniprotkb:P05943 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800369|imex:IM-20067-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:/MGaZckvZx44usKBC50esHsGgy810116 intact-crc:86E47B922CFCAAB6|rigid:v5G8DBsJuf5yjfOxu+zAZcQkOfI false sufficient binding region:1-127 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q8VHU1 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800375 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:q8vhu1_rat(display_long) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800382|imex:IM-20067-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 interpro:IPR030224|interpro:IPR002558(I/LWEQ)|interpro:IPR030554|interpro:IPR035964|go:"GO:0003779"(actin binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0030276"(clathrin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0030136"(clathrin-coated vesicle) - - - figure legend:Table 1|caution:For prey protein Hip1 a human protein is given in table I which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:4MDiHb5Q0Z33aYReM2C7D2hP7tA10116 intact-crc:4322C4A5C58AC15B|rigid:7XdCWT1SHCDg0BQ6GZKD2nXUiKo false sufficient binding region:400-660 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1WC42 uniprotkb:Q62968 intact:EBI-1800394|ensembl:ENSRNOP00000064918 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:b1wc42_rat(display_long)|uniprotkb:Trip6(gene name)|psi-mi:Trip6(display_short)|uniprotkb:LOC686323(gene name synonym)|uniprotkb:rCG_21591(orf name) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800388|imex:IM-20067-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1583180|refseq:NP_001121042.1|ensembl:ENSRNOG00000048580(gene)|ensembl:ENSRNOT00000072838(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|caution:For prey protein Trip6/LOC686323 a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:6GHHnFO41iuefTvu/618g3FbteY10116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:E8C3E28EBFD346A7|rigid:OdvM6AsYuaab8+Gf+sgXQLd7wiE false - sufficient binding region:400-660 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q62632 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800400|ensembl:ENSRNOP00000072839 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:fstl1_rat(display_long)|uniprotkb:Fstl1(gene name)|psi-mi:Fstl1(display_short)|uniprotkb:Frp(gene name synonym)|uniprotkb:Follistatin-like protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800413|imex:IM-20067-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:68955|refseq:NP_077345.1|ensembl:ENSRNOG00000002746(gene)|ensembl:ENSRNOT00000091057(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR011992(EF-Hand type)|interpro:IPR015369(Follistatin)|interpro:IPR036058 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:mwvHeKBWdN3wbhuVLq6GMxkaXg410116 intact-crc:56DF6AC8C852FF45|rigid:1hZgeqdBs6T8S+78JElLQ6v4CQo false sufficient binding region:400-660 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q810W7 uniprotkb:Q62968 intact:EBI-1800424|uniprotkb:Q810W8|ensembl:ENSRNOP00000004646 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:mast1_rat(display_long)|uniprotkb:Mast1(gene name)|psi-mi:Mast1(display_short)|uniprotkb:Sast(gene name synonym)|uniprotkb:Syntrophin-associated serine/threonine-protein kinase(gene name synonym) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800419|imex:IM-20067-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:631372|refseq:NP_851603.1|ensembl:ENSRNOG00000003469(gene)|ensembl:ENSRNOT00000004646(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028777|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489 rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|caution:For prey protein Mast1 a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:ezIgemx0obzyUnCVAR3zgWMut/810116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:0229C12D6899A8A3|rigid:UTTHQ9tq54zzbTmRfc8S5GdQKZ8 false - sufficient binding region:893-1148 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q9QZR8 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800461 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:pdzd2_rat(display_long)|uniprotkb:Pdzd2(gene name)|psi-mi:Pdzd2(display_short)|uniprotkb:Papin(gene name synonym)|uniprotkb:Pdzk3(gene name synonym)|uniprotkb:Pin1(gene name synonym)|uniprotkb:PDZ domain-containing protein 3(gene name synonym)|uniprotkb:Plakophilin-related armadillo repeat protein-interacting PDZ protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800480|imex:IM-20067-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:619958|refseq:NP_075229.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q9QZR8|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0045177"(apical part of cell) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:b0MP8ZEAaMACPmr8rh74d6r0hgs10116 intact-crc:9683E9F7F5B5B707|rigid:vKqbC7kgbGqYsKFpEuhQLwBTTGY false sufficient binding region:893-1148 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63425 uniprotkb:Q62968 intact:EBI-1800492 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:prax_rat(display_long)|uniprotkb:Prx(gene name)|psi-mi:Prx(display_short) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800486|imex:IM-20067-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:619960|refseq:NP_076466.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008366"(axon ensheathment)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021675"(nerve development)|go:"GO:0030054"(cell junction)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0019233"(sensory perception of pain) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:kzZhWc2v9VjCCN2+FXd5hJKjbys10116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:02A2FA0E2125E146|rigid:UUoxzWHHc5MJ3MfkY7MZOKC3hgw false - sufficient binding region:1420-1472 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q63692 uniprotkb:Q62968 intact:EBI-1800513|uniprotkb:Q8CH95 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:cdc37_rat(display_long)|uniprotkb:Cdc37(gene name)|psi-mi:Cdc37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800526|imex:IM-20067-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:71006|refseq:NP_446195.1|interpro:IPR004918(Cdc37)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR038189|mint:Q63692|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|reactome:R-RNO-1227986|reactome:R-RNO-5675482|reactome:R-RNO-8863795|reactome:R-RNO-9013418|reactome:R-RNO-9652282 rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:Wpdi09JErCrAgGUvJfw5BpqN8cc10116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:BDDB227D9A2CB733|rigid:TxaKRD671T8AJ7psrpHHtvmUjkc false - sufficient binding region:1420-1472 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q9Z336 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-920359|ensembl:ENSRNOP00000024656 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:dylt1_rat(display_long)|uniprotkb:Dynlt1(gene name)|psi-mi:Dynlt1(display_short)|uniprotkb:Tctex1(gene name synonym)|uniprotkb:Tctex-1(gene name synonym)|uniprotkb:Activator of G-protein signaling 2(gene name synonym)|uniprotkb:Tctel1(gene name synonym)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800533|imex:IM-20067-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:620261|refseq:NP_112608.1|ensembl:ENSRNOG00000018207(gene)|ensembl:ENSRNOT00000024656(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043657"(host cell)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061564"(axon development)|go:"GO:0099503"(secretory vesicle)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|reactome:R-RNO-6798695 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:sq62mczk30/7gL8RkXNO2CBiTEQ10116 intact-crc:0DE712DD3E2825BD|rigid:HExNpmoLLL1YHsE9++khRdSOrN8 false sufficient binding region:1420-1472 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:B0BN20 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800585|ensembl:ENSRNOP00000005165 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:b0bn20_rat(display_long)|uniprotkb:Tspan6(gene name)|psi-mi:Tspan6(display_short)|uniprotkb:rCG_38183(orf name) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800592|imex:IM-20067-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:1560160|refseq:NP_001094142.1|ensembl:ENSRNOG00000003786(gene)|ensembl:ENSRNOT00000005165(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0039532"(negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503 - - - figure legend:Table 1|caution:For prey protein Tspan6/TM4SF a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:hlP+XaQm8IUHIJoNCvilas5pOEA10116 intact-crc:C33760FFAD29753F|rigid:3XIppzsEI8ErSPrdbn03RCuVFhg false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q5PPL0 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800599 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:q5ppl0_rat(display_long)|uniprotkb:Ndn(gene name)|psi-mi:Ndn(display_short) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800605|imex:IM-20067-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 interpro:IPR030086|interpro:IPR002190(MAGE protein)|rgd:1310526|refseq:NP_001008558.1|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007409"(axonogenesis)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042995"(cell projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0048675"(axon extension)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0071514"(genomic imprinting)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:1990841"(promoter-specific chromatin binding) - - - figure legend:Table 1|caution:For prey protein Ndn a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:cYMXbsQBOoe7NuC+qFaQoeRQfAY10116 intact-crc:52F7007A9A9E9A23|rigid:2ObwFSy5TOsZ6sL3wNqhJvgy32Q false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q62871 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-918392|uniprotkb:Q62872|uniprotkb:Q62873 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:dc1i2_rat(display_long)|uniprotkb:Dync1i2(gene name)|psi-mi:Dync1i2(display_short)|uniprotkb:Dnci2(gene name synonym)|uniprotkb:Dncic2(gene name synonym)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800639|imex:IM-20067-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:620174|dip:DIP-36880N|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9646399|reactome:R-RNO-9648025|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007420"(brain development)|go:"GO:0010970"(transport along microtubule)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031982"(vesicle)|go:"GO:0036157"(outer dynein arm)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|rcsb pdb:2PG1 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:ptqIy3scl8hjZOu5DWFducDvmqY10116 intact-crc:C3B7A882A3274671|rigid:hWUH9vytBES6gpO5a3ds0hMH8Hg false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:P08050 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-476947|uniprotkb:Q53ZE1|ensembl:ENSRNOP00000001054 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:cxa1_rat(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800647|imex:IM-20067-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSRNOT00000001054(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSRNOG00000000805(gene)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1905867"(epididymis development)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P08050|rcsb pdb:1R5S|rcsb pdb:2N8T|rcsb pdb:3CYY|reactome:R-RNO-190840|reactome:R-RNO-190861|reactome:R-RNO-190873|reactome:R-RNO-191650|reactome:R-RNO-196025|reactome:R-RNO-9013406|go:"GO:0005916"(fascia adherens)|go:"GO:0008584"(male gonad development)|go:"GO:0009268"(response to pH)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016020"(membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0007154"(cell communication)|go:"GO:0030054"(cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|rgd:2690|refseq:NP_036699.1|dip:DIP-34793N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:qRGPHCApRj9/xiPxo1KW9D/xE5w10116 intact-crc:1075AD1F06F3E1A3|rigid:cfe3doct45V9gezOnWLZsXEvvU4 false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q5XIP1 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800655|ensembl:ENSRNOP00000075562 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:pelo_rat(display_long)|uniprotkb:Pelo(gene name)|psi-mi:Pelo(display_short) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800667|imex:IM-20067-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:1359591|refseq:NP_001007635.1|ensembl:ENSRNOG00000061128(gene)|ensembl:ENSRNOT00000091499(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226 - - - figure legend:Table 1|caution:For prey protein Pelo a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:JGhMJZGtGBhScRWEviAFBLY4VQ010116 intact-crc:3802A1775E778909|rigid:CLvLeqauD0C2K2u8N2u+N9c3ZjM false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:O35763 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-915533 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:moes_rat(display_long)|uniprotkb:Msn(gene name)|psi-mi:Msn(display_short)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800676|imex:IM-20067-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019747|rgd:621260|refseq:NP_110490.1|interpro:IPR019749|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR029071|mint:O35763|interpro:IPR035963|interpro:IPR041789|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031143"(pseudopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042098"(T cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|reactome:R-RNO-437239 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:5JGEl/oxEgX4eh5kE9+J394ontE10116 intact-crc:47AA66790779FB31|rigid:sAG8b+Luqa1sn+gf2s0FX4Iwt1w false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:P68370 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800684|imex:IM-20067-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116 intact-crc:7FAB9D78F450E7D8|rigid:JnJnrandcbZQFC6AFQvVNrnhJsQ false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G3V7G9 uniprotkb:Q62968 intact:EBI-1800690|uniprotkb:Q498D2|ensembl:ENSRNOP00000014817 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:g3v7g9_rat(display_long)|uniprotkb:Eif3l(gene name)|psi-mi:Eif3l(display_short)|uniprotkb:Eif3s6ip(gene name synonym) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800697|imex:IM-20067-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1308230|refseq:NP_001029306.1|ensembl:ENSRNOG00000011020(gene)|ensembl:ENSRNOT00000014817(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|reactome:R-RNO-156827|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706 rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|caution:"For prey protein Eif3s6ip a mouse protein (XM_110140)is given in Table 1 which has been mapped to the corresponding rat protein."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:9v95mEC3uFsGZr6gDg/18HwVKsc10116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:31FFCD35E1B94F4B|rigid:sAz1Vsdl9eG1bjXQCgiG0tYB5MQ false - sufficient binding region:1724-1844 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A7U7N4 uniprotkb:Q62968 intact:EBI-1800717|ensembl:ENSRNOP00000039441 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 psi-mi:a7u7n4_rat(display_long)|uniprotkb:rCG_26908(orf name)|uniprotkb:Prnd(gene name)|psi-mi:Prnd(display_short) psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800723|imex:IM-20067-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1306618|refseq:NP_001095901.1|refseq:XP_006235120.1|ensembl:ENSRNOG00000021260(gene)|ensembl:ENSRNOT00000050900(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007338"(single fertilization)|go:"GO:0007340"(acrosome reaction)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR021566|interpro:IPR022416|interpro:IPR036924|reactome:R-RNO-163125 rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 - - - figure legend:Table 1|caution:For prey protein Prnp a mouse protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:T2zDlsiYYqgs7juSx0WLaBRbW7w10116 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 intact-crc:C5DD0538CB1F9B0C|rigid:tcv8Jjr4zma6TsO7aIJYMfnp1sQ false - sufficient binding region:1724-1844 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q9JLS3 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800729|uniprotkb:A6BM05 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:taok2_rat(display_long)|uniprotkb:Taok2(gene name)|psi-mi:Taok2(display_short)|uniprotkb:Tao2(gene name synonym)|uniprotkb:Thousand and one amino acid protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800747|imex:IM-20067-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:621590|refseq:NP_073193.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:1U5Q|rcsb pdb:1U5R|rcsb pdb:2GCD|go:"GO:0000165"(MAPK cascade)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007409"(axonogenesis)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038191"(neuropilin binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150019"(basal dendrite morphogenesis)|go:"GO:0150020"(basal dendrite arborization)|go:"GO:0044294"(dendritic growth cone) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:++NpdKNc2qP1w/h5WEuhasVMdno10116 intact-crc:961FAE07BBDE3924|rigid:MSKCpSTxteDOCV4RvfeE48sdiPE false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q5BK07 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800753|ensembl:ENSRNOP00000003685 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:ccd43_rat(display_long)|uniprotkb:Ccdc43(gene name)|psi-mi:Ccdc43(display_short) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800759|imex:IM-20067-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:1311929|refseq:NP_001094198.1|ensembl:ENSRNOG00000002748(gene)|ensembl:ENSRNOT00000003685(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR037666 - - - figure legend:Table 1|caution:"For prey protein Ccdc43 a mouse protein (AK011254) is given in Table 1 which has been mapped to the corresponding rat protein."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:viuPANnXDml4XGD6OzR9RlTphaw10116 intact-crc:E958A7C1C0E3D338|rigid:8xCsYVvoItvhOMu/e8gohLNa0uo false sufficient binding region:1724-1844 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:P62161 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800765|imex:IM-20067-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116 intact-crc:A1D5832F34719440|rigid:t8Uw6WjuzLGfzxjZYQsMcSVFTU8 false sufficient binding region:1842-1956 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:P60711 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800814|imex:IM-20067-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116 intact-crc:828F3D6ECC73CB21|rigid:xPgUTq/4AA2FlftLSyzD4909+xs false sufficient binding region:1842-1956 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:P69735 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800832 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:rb3gp_rat(display_long)|uniprotkb:Rab3gap1(gene name)|psi-mi:Rab3gap1(display_short)|uniprotkb:Rab3gap(gene name synonym)|uniprotkb:RAB3 GTPase-activating protein 130 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p130(gene name synonym) psi-mi:"MI:0018"(two hybrid) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800843|imex:IM-20067-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 reactome:R-RNO-6811436|reactome:R-RNO-8876198|rgd:1306487|interpro:IPR026147|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0007420"(brain development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021854"(hypothalamus development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060325"(face morphogenesis)|go:"GO:0061646"(positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098794"(postsynapse)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly) - - - figure legend:Table 1|caution:For prey protein Rab3gap1 a human protein is given in Table 1 which has been mapped to the corresponding rat protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:bebbfMZUY3wLu5BvCnusBHMBaso10116 intact-crc:E41E5355EA2A5BAA|rigid:nBmo43ZFII4lM4FahAJ3bEE5ynA false sufficient binding region:1842-1956 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q62968 uniprotkb:Q63425 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-1800492 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:prax_rat(display_long)|uniprotkb:Prx(gene name)|psi-mi:Prx(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800867|imex:IM-20067-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:619960|refseq:NP_076466.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008366"(axon ensheathment)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021675"(nerve development)|go:"GO:0030054"(cell junction)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0019233"(sensory perception of pain) - - - figure legend:Fig 3|comment:"A Scn10a fusion construct comprising the intracellular loop IV (aa 1420-1470) and the immunoreactive C-terminus has been used."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:kzZhWc2v9VjCCN2+FXd5hJKjbys10116 intact-crc:C0DA691256DDF337|rigid:UUoxzWHHc5MJ3MfkY7MZOKC3hgw false - ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q62968 uniprotkb:Q9Z336 intact:EBI-1800320|uniprotkb:Q63554|uniprotkb:Q6EWG6|ensembl:ENSRNOP00000047944 intact:EBI-920359|ensembl:ENSRNOP00000024656 psi-mi:scnaa_rat(display_long)|uniprotkb:Scn10a(gene name)|psi-mi:Scn10a(display_short)|uniprotkb:Sns(gene name synonym)|uniprotkb:Sodium channel protein type X subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.8(gene name synonym)|uniprotkb:Peripheral nerve sodium channel 3(gene name synonym)|uniprotkb:Sensory neuron sodium channel(gene name synonym) psi-mi:dylt1_rat(display_long)|uniprotkb:Dynlt1(gene name)|psi-mi:Dynlt1(display_short)|uniprotkb:Tctex1(gene name synonym)|uniprotkb:Tctex-1(gene name synonym)|uniprotkb:Activator of G-protein signaling 2(gene name synonym)|uniprotkb:Tctel1(gene name synonym)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Malik-Hall et al. (2003) pubmed:12591166|imex:IM-20067 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1800891|imex:IM-20067-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3629|refseq:NP_058943.1|ensembl:ENSRNOG00000032473(gene)|ensembl:ENSRNOT00000046864(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044299"(C-fiber)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0061337"(cardiac conduction)|go:"GO:0071439"(clathrin complex)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028809|interpro:IPR043203|interpro:IPR044564|reactome:R-RNO-5576892 rgd:620261|refseq:NP_112608.1|ensembl:ENSRNOG00000018207(gene)|ensembl:ENSRNOT00000024656(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043657"(host cell)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061564"(axon development)|go:"GO:0099503"(secretory vesicle)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|reactome:R-RNO-6798695 - - - figure legend:Fig. 3|comment:"A Scn10a fusion construct comprising the intracellular loop IV (aa 1420-1470) and the immunoreactive C-terminus has been used."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2008/08/08 2014/10/16 rogid:pOcv5fn4mMg5YmWNsvdrWdN18I410116 rogid:sq62mczk30/7gL8RkXNO2CBiTEQ10116 intact-crc:2D236808DCFB493B|rigid:HExNpmoLLL1YHsE9++khRdSOrN8 false - ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)