#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q3TYD6	uniprotkb:P41236	intact:EBI-2008910|uniprotkb:A6BLY9|uniprotkb:Q6PDK6|uniprotkb:Q6ZPY9|uniprotkb:Q8CA34|ensembl:ENSMUSP00000048238	intact:EBI-1056517|ensembl:ENSP00000484580	psi-mi:lmtk2_mouse(display_long)|uniprotkb:Lmtk2(gene name)|psi-mi:Lmtk2(display_short)|uniprotkb:Brek(gene name synonym)|uniprotkb:Kiaa1079(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)	psi-mi:ipp2_human(display_long)|uniprotkb:PPP1R2(gene name)|psi-mi:PPP1R2(display_short)|uniprotkb:IPP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2008906|imex:IM-20116-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001074578.1|ensembl:ENSMUSG00000038970(gene)|ensembl:ENSMUST00000041804(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:NP_006232.1|ensembl:ENSG00000184203(gene)|ensembl:ENST00000618156(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)")|refseq:NP_001303254.1|dip:DIP-781N	-	-	-	caution:The authors describe the prey as a human protein but as they used a murine library, it has been assumed they mapped a mouse sequence onto a human.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/06	2014/10/16	rogid:LNtGJwWsdlqp/3OURg3hQ+2qRfc10090	rogid:Kf816t+iy7T4OA28eT6cN4v471s9606	intact-crc:CEC8F7A150EEE4EC|rigid:NpQDXufbQpJjuRzn2upLL1hDZMw	false	sufficient binding region:1344-1450	sufficient binding region:1-197	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWU2	-	intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293	-	psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym)	-	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:9606(human)|taxid:9606(Homo sapiens)	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2008963|imex:IM-20116-2	-	-	psi-mi:"MI:0499"(unspecified role)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2	-	go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Autophosphorylation of LMTK2|figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/06	2014/10/16	rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606	-	intact-crc:81D5619F94062BB6	false	sufficient binding region:94-600|his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	-
uniprotkb:Q8IWU2	uniprotkb:P41236	intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293	intact:EBI-1056517|ensembl:ENSP00000484580	psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym)	psi-mi:ipp2_human(display_long)|uniprotkb:PPP1R2(gene name)|psi-mi:PPP1R2(display_short)|uniprotkb:IPP2(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2008972|imex:IM-20116-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2	refseq:NP_006232.1|ensembl:ENSG00000184203(gene)|ensembl:ENST00000618156(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)")|refseq:NP_001303254.1|dip:DIP-781N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of PPP1R2|comment:PPP1R2 was a relatively poor substrate for LMTK2|figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/06	2014/10/16	rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606	rogid:Kf816t+iy7T4OA28eT6cN4v471s9606	intact-crc:A52F8A4A50B31836|rigid:jUh7IUuMhoobHr0PHNa+cpxNF7g	false	sufficient binding region:94-600	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62139	uniprotkb:Q8IWU2	intact:EBI-2008988|uniprotkb:P08128|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802	intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293	psi-mi:pp1a_rabit(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009044|imex:IM-20116-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_001095176.1|rcsb pdb:1FJM|interpro:IPR031675|interpro:IPR029052|interpro:IPR037979|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901567"(fatty acid derivative binding)|go:"GO:1904886"(beta-catenin destruction complex disassembly)	refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	figure legend:Fig. 4B|comment:Although PPP1C was purified, probably as a complex, phosphorylation of the alpha subunit was confirmed by site-specific antibodies.|resulting-ptm:P62139  Thr-320 O-phospho-L-tyrosine|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2008/10/06	2014/10/16	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9986	rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606	intact-crc:927565B3B8773317|rigid:r6t2nmEQfZteTnvRED+rw61fz58	false	-	his tag:?-?|sufficient binding region:94-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IWU2	uniprotkb:P41236	intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293	intact:EBI-1056517|ensembl:ENSP00000484580	psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym)	psi-mi:ipp2_human(display_long)|uniprotkb:PPP1R2(gene name)|psi-mi:PPP1R2(display_short)|uniprotkb:IPP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009085|imex:IM-20116-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2	refseq:NP_006232.1|ensembl:ENSG00000184203(gene)|ensembl:ENST00000618156(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)")|refseq:NP_001303254.1|dip:DIP-781N	-	-	-	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2008/10/06	2014/10/16	rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606	rogid:Kf816t+iy7T4OA28eT6cN4v471s9606	intact-crc:D0AD4A25F90208B8|rigid:jUh7IUuMhoobHr0PHNa+cpxNF7g	false	flag tag:?-?|sufficient binding region:1099-1503	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWU2	uniprotkb:P41236	intact:EBI-2008933|uniprotkb:Q75MG7|uniprotkb:Q9UPS3|uniprotkb:A4D272|ensembl:ENSP00000297293	intact:EBI-1056517|ensembl:ENSP00000484580	psi-mi:lmtk2_human(display_long)|uniprotkb:LMTK2(gene name)|psi-mi:LMTK2(display_short)|uniprotkb:AATYK2(gene name synonym)|uniprotkb:BREK(gene name synonym)|uniprotkb:KIAA1079(gene name synonym)|uniprotkb:KPI2(gene name synonym)|uniprotkb:LMR2(gene name synonym)|uniprotkb:Lemur tyrosine kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase KPI-2(gene name synonym)|uniprotkb:Kinase/phosphatase/inhibitor 2(gene name synonym)|uniprotkb:Apoptosis-associated tyrosine kinase 2(gene name synonym)|uniprotkb:Brain-enriched kinase(gene name synonym)|uniprotkb:CDK5/p35-regulated kinase(gene name synonym)	psi-mi:ipp2_human(display_long)|uniprotkb:PPP1R2(gene name)|psi-mi:PPP1R2(display_short)|uniprotkb:IPP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2002)	pubmed:12393858|imex:IM-20116	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2009116|imex:IM-20116-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055731.2|ensembl:ENSG00000164715(gene)|ensembl:ENST00000297293(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030426"(growth cone)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0070853"(myosin VI binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8IWU2	refseq:NP_006232.1|ensembl:ENSG00000184203(gene)|ensembl:ENST00000618156(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007062("Protein phosphatase inhibitor 2 (IPP-2)")|refseq:NP_001303254.1|dip:DIP-781N	-	-	-	figure legend:Fig. 8|comment:In yeast PPP1R2 appeared to require the presence of PPP1C for binding to LMTK2, in Cos-7 cells this was not the case.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2008/10/06	2014/10/16	rogid:oD9P04WV3KZ1/8TW4eDYqqNqDkA9606	rogid:Kf816t+iy7T4OA28eT6cN4v471s9606	intact-crc:7C92A54032E433A0|rigid:jUh7IUuMhoobHr0PHNa+cpxNF7g	false	sufficient binding region:1099-1503|mutation disrupting interaction:1356-1356,1358-1358	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)